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[ ", the association between malaria and intestinal helminth coinfection in pregnancy and stillbirth has not been studied . few studies have studied the association between malaria and helminths in pregnancy , with conflicting results . given that 98% of stillbirths occur in developing countries , especially sub - sa...	objective . the objective of the study was to assess plasmodium / intestinal helminth infection in pregnancy and other risk factors for stillbirth in ghana . methods . a cross - sectional study of women presenting for delivery in two hospitals was conducted during november - december 2006 . data collected included soci...
[ "we previously reported a novel subtype of type 1b diabetes that we referred to fulminant type 1 diabetes . in fulminant type 1 diabetes type 1 diabetes is characterized by insulin deficiency resulting from destruction of pancreatic cells and subclassified into type 1a ( autoimmune ) and type 1b ( idiopathic ) diab...	abstractfulminant type 1 diabetes is characterized by almost complete cell destruction , resulting in scarce insulin secretion . in the present study , we aimed to clarify clinical features related to serum cpeptide levels measured by a high sensitivity method , chemiluminescent enzyme immunoassay , in 12 patients with...
[ "the cnt were functionalized by a 1,3-dipolar cycloaddition reaction of azomethine ylides using a one - pot functionalization procedure described elsewhere13 leading to the formation of pyrrolidine - type groups bonded to the cnt surface . two types of cnt were investigated , nc7000 from nanocyl and mwnt sa from s...	graphene nanoribbons ( gnr ) were generated in ethanol solution by unzipping pyrrolidine - functionalized carbon nanotubes under mild conditions . evaporation of the solvent resulted in regular few - layer stacks of graphene nanoribbons observed by transmission electron microscopy ( tem ) and x - ray diffraction . the ...
[ "this paper focuses on interspecies pathogenic interactions within the red complex , in particular the combinations of p. gingivalis - t . these bacteria are not usually found alone , but in combination in the periodontal pockets , suggesting that some bacteria may cause destruction of the periodontal tissue in a c...	the red complex , which includes porphyromonas gingivalis , treponema denticola , and tannerella forsythia ( formerly bacteroides forsythus ) , are recognized as the most important pathogens in adult periodontal disease . these bacteria are usually found together in periodontal pockets , suggesting that they may cause ...
[ "the cls was developed to continuously monitor habitual iop fluctuations over a 24-hour period by measuring changes in the eye s circumference in the area of the corneoscleral junction.12,13 once a cls is placed on an eye , the iop fluctuation can be measured automatically without interference with the subject s sl...	purposewe investigated correlations between short - term and long - term intraocular pressure ( iop ) fluctuations.methodswe examined 50 eyes of glaucoma patients who were followed for > 2 years . we measured short - term iop fluctuation using a triggerfish contact lens sensor ( cls ) . the short - term iop fluctuation...
[ "the aim of this study was to evaluate the influence of three different luting protocols ( total - etch , self - etch , and self - adhesive ) on shear bond strength of cad / cam rnc material , based on cad / cam technology , to dentin . resin cements have been selected for their advantageous mechanical and adhesive...	background : the purpose of this study was to evaluate the influence of three different luting protocols on shear bond strength of computer aided design / computer aided manufacturing ( cad / cam ) resin nanoceramic ( rnc ) material to dentin.materials and methods : in this in vitro study , 30 disks were milled from rn...
[ "therefore , the goals of this study were to evaluate volume - based care for women with uterine cancer aged 50 years and younger using a statewide population database . recently , there has been an interest in elucidating patterns of care for patients treated with uterine cancer . uterine cancer is the most common...	purpose . to characterize volume - based care of uterine cancer among women aged 50 years . methods . the maryland health service cost review commission database was accessed for uterine cancer surgical cases from 1994 to 2005 . cross - tabulations and logistic regression models were used to evaluate for significant as...
[ "in iden 2012 , many diverse experiences associated with basic procedures to advanced techniques of endoscopic retrograde cholangiopancreatography ( ercp ) were highlighted in great enthusiastic lectures by world renowned experts . interesting cases entitled \" interesting cases in pancreatobiliary endoscopy \" wer...	the pancreatobiliary organ is composed of one of the most complicated structures and complex physiological functions among other digestive organs in our body . this is why endoscopic procedure in pancreaticobiliary system requires rather complicated techniques . in international digestive endoscopy network ( iden ) 201...
[ "regarding to complications related to b19 virus infection during pregnancy and lack of study about its infection prevalence in ardabil county , this study was conducted with the aim of determination of the prevalence of parvovirus and igg in pregnant women in ardabil . , we tried to determine prevalence of serum p...	background and objectives : trans - placental transmission of parvovirus b19 during pregnancy can causes adverse outcomes . regarding its importance in prenatal care , we decided to study prevalence of parvovirus b19 infection among pregnant woman in ardabil , iran.materials and methods : in a community based study wit...
[ "there is both growing recognition and scientific evidence that interventions of physical activity and exercise programs ( paeps ) have a favorable impact on patients with psychiatric disorders.17 these findings have been reported among groups of patients with major depressive disorders ( mdds),6,8,9 schizophrenia,...	backgroundphysical activity and exercise programs ( paeps ) are an important factor in increasing and maintaining physical and mental health . this holds particularly true for patients with psychiatric disorders undergoing treatment in a psychiatric hospital . to understand whether the benefits reported in the literatu...
[ "the aims of this study were to ( 1 ) determine current practice of np 's assessment of and intervention strategies with older adult drivers in southeastern north carolina ; ( 2 ) assess the nps knowledge deficits in assessing safe driving capability of the older adults ; and ( 3 ) assess nps current knowledge of r...	as the silver tsunami continues , assessing and intervening with older adult drivers are becoming an essential aspect of the comprehensive geriatric exam . the current lack of time efficient clinical guidelines is a concern and barrier for nps . the purpose of this study was to identify strategies currently used by nps...
[ "left ventricular noncompaction cardiomyopathy ( lvnc ) is a very rare cardiomyopathy characterized by an increase in the noncompacted , trabeculated myocardium adjacent to compacted myocardium in the left ventricular ( lv ) . we present a case of lvnc in an adult patient with its clinical and imaging findings . th...	left ventricular noncompaction cardiomyopathy is a very rare condition , yet believed to be often overlooked . it is thought to be caused by the developmental arrest in embryogenesis and characterized by an increase in the noncompacted , trabeculated myocardium adjacent to compacted myocardium in the left ventricular ....
[ "the objective of this study was to analyze the clinical records of lung cancer patients who underwent surgical resection to evaluate the clinical characteristics and outcomes of patients with incidentally detected lung cancer and patients with symptomatic lung cancer . there is little information , however , on th...	objective . to evaluate clinical characteristics and outcomes in incidentally detected lung cancer and in symptomatic lung cancer . material and methods . we designed a retrospective study including all patients undergoing pulmonary resection with a curative intention for nsclc . they were classified into two groups ac...
[ "the main objective of our study was to show the long - term effects of fusion on the adjacent joints using our technique . the frequency of these complaints seems to be predicted by the alignment of the fusion which should be optimal [ 3 , 6 , 12 ] . in our clinic , we perform hip fusions with our standard techniq...	even in current orthopaedic practice , some cases are still not suitable candidates for hip replacement and hip fusion remains the only option in these highly selected patients . in this retrospective study we describe the long - term clinical outcome , quality of life and radiological evaluation of all adjacent joints...
[ ", we have divided the current review into two sections focusing on ( 1 ) protozoan infection and ( 2 ) helminth infection . lts play important roles in both th1 and th2 immune responses , which are involved in the defense against protozoan and helminth infections , respectively . in light of the current research o...	leukotrienes ( lts ) , formed by the 5-lipoxygenase-(5-lo- ) catalyzed oxidation of arachidonic acid , are lipid mediators that have potent proinflammatory activities . pharmacologic or genetic inhibition of 5-lo biosynthesis in animals is associated with increased mortality and impaired clearance of bacteria , fungi ,...
[ "we recently provided evidence that deficiencies in enzymes responsible for replicating g quadruplex ( g4 ) structures , such as the specialized dna polymerase rev1 and helicases fancj , wrn , and blm , can lead to localized changes in histone modifications and gene expression ( sarkies et al . we proposed that pe...	summarynucleotide pool imbalance has been proposed to drive genetic instability in cancer . here , we show that slowing replication forks by depleting nucleotide pools with hydroxyurea ( hu ) can also give rise to both transient and permanent epigenetic instability of a reporter locus , bu-1 , in dt40 cells . hu induce...
[ "our strategy utilizes fourier transform ( ft)-based measurements in the solar portion of the optical spectrum , for optimally combining spatial resolution , spectral resolution , speed , and dynamic range . we have developed a set of small area , high - brightness spectroscopies that are appropriate for characteri...	we present a methodology for probing light - matter interactions in prototype photovoltaic devices consisting of an organic semiconductor active layer with a semitransparent metal electrical contact exhibiting surface plasmon - based enhanced optical transmission . we achieve high - spectral irradiance in a spot size o...
[ "based on comprehensive studies of hsps , this review offers important information regarding the mechanism related with the characteristic procedure of signal pathway according to the specifically cared substrate of each hsp , structural characteristics , specifically expressed location and those roles . accumulate...	molecular chaperones are ubiquitous and abundant within cellular environments , functioning as a defense mechanism against outer environment . the range of molecular chaperones varies from 10 to over 100 kda . depending on the size , the specific locations and physiological roles of molecular chaperones vary within the...
[ "adenoid cystic carcinoma was first described by billroth in 1859 and called \" cylindroma \" due to its characteristic histologic appearance1 . in 1953 , adenoid cystic carcinoma is a malignant salivary gland tumour characterized by a deceptive histologic pattern , indolent , locally invasive growth with high prop...	adenoid cystic carcinoma is a rare epithelial tumour , and comprises about 1% of all malignant tumours of the oral and maxillofacial region . it is a malignant tumour which may develop in the trachea , bronchus , lungs or mammary glands , in addition to the head and neck region . occurrences in the head and neck are mo...
[ ", we share the design and implementation of the registry and propose a management information system for diabetes registry in puducherry district . a community - based cohort study showed the incidence of diabetes in rural puducherry to be 21.5 for 1000 person - year follow - up . in this context , a pilot project...	background : diabetes registries monitor the population prevalence and incidence of diabetes , monitor diabetes control program , provide information of quality of care to health service providers , and provide a sampling frame for interventional studies . this study documents the process of establishing a prospective ...
[ "therefore , this study was conducted to understand the association of sh with abnormalities in the serum lipid profile and aip in apparently healthy adult females . the study also aims to find out whether any correlation exists between aip and serum tsh levels among sh cases . thus , though the effect of overt hyp...	background : a controversy exists regarding the association between subclinical hypothyroidism ( sh ) and dyslipidemia . moreover , studies on lipid ratios and atherogenic index of plasma ( aip ) in sh are rare , particularly in the indian scenario.aim:this study aimed to investigate abnormalities in conventional lipid...
[ "this review discusses the regulation of hif- by gsk-3 and compares it with hydroxylase - dependent hif- protein regulation . indeed , different kinases , among them glycogen synthase kinase 3 ( gsk-3 ) , have been identified to directly phosphorylate hif- proteins . the ability of mammals to respond to an inadequa...	hypoxia - inducible factors ( hifs ) , consisting of - and -subunits , are critical regulators of the transcriptional response to hypoxia under both physiological and pathological conditions . to a large extent , the protein stability and the recruitment of coactivators to the c - terminal transactivation domain of the...
[ "of relevance to the current study , there is evidence that fs cells play a role in the absorption of ions and water from the luminal spaces [ 46 ] , which could involve the activity of an apical na / h exchanger . the current results support the view that fs cells play a major role in regulating the ionic compos...	genetic ablation of the nhe2 na+/h+ exchanger causes gastric achlorhydria , absorptive defects in kidney and colon , and low fertility . here we show that nhe2 is expressed in the pituitary , with the highest mrna expression in pars distalis and lower expression in pars intermedia . in pars distalis of nhe2-null mice ,...
[ "autonomic neuropathy ( an ) has long been recognized as a significant health risk and leads to reduced quality of life ( qol ) , increased mortality and morbidity and increased health care costs ( 1 - 2 - 3 ) . our hypotheses are that the beta - blocker , metoprolol , would inhibit sympathetic tone less than the c...	backgroundcardiovascular autonomic neuropathy ( can ) is recognized as a significant health risk , correlating with risk of heart disease , silent myocardial ischemia or sudden cardiac death . beta - blockers are often prescribed to minimize risk.objectivesin this second of two articles , the effects on parasympathetic...
[ "2location of barcelos , state of amazonas , brazil , 2010 , and number of blood samples collected by teams ( a - f ) and city district for screen tests . \n \n the city of barcelos , where this study was conducted , is located on the right bank of the negro river , 490 km from manaus , the capital of am ( \n fig ....	the serology of human trypanosoma cruzi infection in the rio negro microregion is very complex because of the large numbers of false - positive cases that result from low antibody titres and cross - reactions with other infections . in the present study , we collected 4,880 blood samples on filter paper ; of these ...
[ "survival data were evaluated according to the histologic tumor types , presence or absence of lymph node metastasis , number of lymph nodes involved , classification of lymph node metastasis , area of metastasis , number of metastatic foci , maximum diameter of metastasis , and tma . animals that were alive and th...	backgroundas in women , regional lymph node status impacts survival in dogs with malignant mammary tumors . however , few studies have evaluated regional lymph node metastases in dogs with malignant mammary gland tumors.objectivesto estimate overall survival based on the assessments of the lymph node status and the mor...
[ "these lesions though may cause life threatening hemorrhage , watchful observation is still considered as a treatment option in these patients .", "a 71-year - old male presented with pulsatile swelling over the right side of face and over the forehead in october 2009 . patient was evaluated with computed tomogra...	aneurysms of external carotid artery are rare . treatments for these are undertaken for the prevention of complications like hemorrhage or rupture , and embolism . we present a 71-year - old male with idiopathic multiple aneurysm for the past 34 years on conservative management and regular follow up for the past 4 year...
[ "this paper examines the personality of mothers and its relationship to severity of addiction of their sons . offspring interactions can dramatically influence the child s behavior as they age.1 the focus of this study is to examine retrospectively the potential relationship between maternal personality characteris...	drug addicts often come from dysfunctional families . the prevailing view in the literature is that mothers of drug - dependent patients can be characterized by strong emotional bonds and overprotection . studies suggest that maternal rejection could be a major risk factor of developing drug addiction . this work is a ...
[ "could mediate in inflammatory cytokines regulation , we study the effect of our extracts on ox - ldl - activated thp-1 macrophages , measuring the expression and release of several inflammatory mediators . designed to identify natural compounds with anti - inflammatory potential , we have studied thyme oils from t...	properties of thyme extracts from three different species ( thymus vulgaris , thymus zygis , and thymus hyemalis ) were examined . two oil fractions from each species were obtained by co2 supercritical fluid extraction . main compounds presented in the supercritical extracts of the three thyme varieties were 1,8 cineol...
[ "one of its main indices is the number of published articles or science production in a specific field of sciences . in addition , citations of papers is another index that mostly is used as a proxy of application of papers . aim to monitoring and assessment of scientific trends , scientometrics provides reliable ,...	background : researchers , practitioners , and policy - makers call for updated valid evidences to monitor , prevent , and control of alarming trends of obesity . we quantify the trends of obesity / overweight researches outputs of middle east countries.methods:we systematically searched scopus database as the only sou...
[ "the sagittal alignment of the spine has important ramifications to the health - related quality of life.1 it varies with age,2 \n 3 gender,4 spinal disease,5 \n 6 and body position.7 \n 8 \n 9 \n 10 many researchers have evaluated the sagittal alignment of the cervical spine . however , they used different neck po...	study design retrospective radiologic study . objective the sagittal alignment of the cervical spine can be evaluated using either a lateral cervical radiograph or a whole - spine lateral view on which the cervical spine is included . to our knowledge , however , no report has compared the two . the purpose of this...
[ "this \n family is identified by the presence of a cyclohexene ring spiro - linked \n to a tetronic acid moiety ( figure 1 , fragment \n a ) that is embedded in a macrocycle ( figure 1 , fragment b ) . in several cases , the structure also contains a trans - decalin ring ( figure 1 , fragment \n c ) and is decorate...	the discovery of chlorothricin ( 1 ) defined a new family of microbial metabolites with potent antitumor antibiotic properties collectively referred to as spirotetronate polyketides . these microbial metabolites are structurally distinguished by the presence of a spirotetronate motif embedded within a macrocycl...
[ "thus , in order to understand and combat candida pathogenesis , it is important to study candida biology directly , and having access to the phased genome assembly opens up multiple new research opportunities . the candida genome database ( cgd , http://www.candidagenome.org/ ) is a freely available online resourc...	the candida genome database ( cgd , http://www.candidagenome.org/ ) is a freely available online resource that provides gene , protein and sequence information for multiple candida species , along with web - based tools for accessing , analyzing and exploring these data . the mission of cgd is to facilitate and acceler...
[ "the interaction term for osa and obesity on homa- was calculated to determine whether the association between osa and homa- was modified by obesity status . to exclude the potential confounding effect of medication for diabetes or dyslipidemia on glucose metabolism in addition , to examine the additive effect of e...	objectivethe purpose of this study was to investigate whether the impact of obstructive sleep apnea ( osa ) on glucose metabolism was different according to the presence or absence of obesity.research design and methodsa total of 1,344 subjects > 40 years old from the korean genome and epidemiology study were included ...
[ ", we present magnetic resonance imaging ( mri ) and fluorine-18-fluorodeoxyglucose ( f - fdg ) positron emission tomography ( pet)/ct findings in a patient with primary uterine peripheral t - cell lymphoma . however , the diagnosis of primary uterine lymphoma is often delayed due to its low incidence and nonspecif...	abstractprimary uterine non - hodgkin 's lymphoma is extremely rare accounting for < 1% of all extranodal non - hodgkin 's lymphomas . imaging findings of primary uterine lymphoma have rarely been reported before . we present magnetic resonance imaging ( mri ) and fluorine-18-fluorodeoxyglucose ( 18f - fdg ) positron e...
[ "recent data have proposed that this might be a consequence of neurovascular compression on the left ventrolateral medulla . there is evidence for this in the heart , kidney and skeletal muscle but it has not been confirmed in studies of the hepatomesenteric circulation . in other words , it is difficult to provide...	abstractit has been known for some considerable time that sustained hypertension changes the circulatory architecture both in the heart and blood vessels . the histopathological alterations are of considerable interest because once they have developed they appear to carry an adverse prognostic risk . in the heart it is...
[ ", we summarize evidence from both animal models and human studies on the in vivo functions of the annexin a2/s100a10 system . annexin a2 ( a2 ) belongs to the annexin family of ca - regulated phospholipid binding proteins , which are expressed in plants , animals , and protists throughout the phylogenetic tree . ,...	since its discovery as a src kinase substrate more than three decades ago , appreciation for the physiologic functions of annexin a2 and its associated proteins has increased dramatically . with its binding partner s100a10 ( p11 ) , a2 forms a cell surface complex that regulates generation of the primary fibrinolytic p...
[ "", "however , the outcome of pregnancy in dialysis patients has been much improved , and the overall rate of successful fetal outcome is reported to be 76% ( 1 ) . pregnancy in patients with end - stage renal disease ( esrd ) is rare , and kidney disease before pregnancy is associated with poor fetal outcome . w...	recent advances in dialysis and a multidisciplinary approach to pregnant patients with advanced chronic kidney disease provide a better outcome . a 38-yr - old female with autosomal dominant polycystic kidney disease ( adpkd ) became pregnant . she was undergoing hemodialysis ( hd ) and her kidneys were massively enlar...
[ "a 78-year - old woman presented with weakness , fatigue and hemoglobin of 8.3 g / dl , to another clinic in september , 2009 , and she was given erythrocyte suspension replacement . since her transfusion dependency increased , she was considered for lenalidomide treatment in april , 2013 . after 10 days of treatme...	5q - syndrome is a special subgroup of myelodysplastic syndrome in terms of follow - up and treatment . lenalidomide is an immunomodulatory drug that is frequently used in the treatment of multiple myeloma . some clinical studies have shown that lenalidomide treatment is effective in 5q syndrome and significantly decre...
[ "afterwards , many researches conducted on the level of response to hbv vaccine among iranian children and ample data on the coverage rate of vaccine together with evaluation of vaccine responsiveness published in iran so far . in this study , a systematic review and meta - analysis was performed to provide the sta...	context : hepatitis b virus expanded program on immunization ( epi ) started on 1993 in iran . most surveys have assessed the level of response to vaccine by measuring the titers of anti - hbs . this meta- analysis aimed to summarize the iranian published data on the rate of vaccine - responders versus non - responders...
[ "avoiding glenoid component malposition in terms of version and inclination is therefore an important technical goal , which may be very demanding due to a variety of issues related to patient anatomy and surgical technique . it is the most recent development in this field , and its effectiveness in both the versio...	shoulder arthroplasty is a demanding procedure with a known complication rate . most complications are associated with the glenoid component , a fact that has stimulated investigation into that specific component of the implant . avoiding glenoid component malposition is very important and is a key reason for recent de...
[ "despite expanded indications for conservative surgery of urothelial tumors ( ut - formerly transitional cell carcinoma ) of the upper urinary tract ( uut ) , radical nephroureterectomy ( nue ) with complete removal of the distal ureter including the bladder cuff is the standard surgical technique used for most pat...	introductionwe present a cohort of patients with low - stage pelviureteric neoplastic disease who underwent complete laparoscopic nephroureterectomy ( clnue ) with intravesical lockable clip ( ivlc ) . due to the absence of a standard technique of nue , the study was not randomized.materialsfrom 1/2010 to 1/2012 , 21 p...
[ "segmental copy - number variations ( cnvs ) , involving the gain or loss of several hundreds of bases to several hundred kilobases ( kb ) of the genome , can be an important source of genetic variation among human populations of different ethnic groups as well as among individuals . therefore , more data regarding...	segmental copy - number variations ( cnvs ) may contribute to genetic variation in humans . reports of the existence and characteristics of cnvs in a large japanese cohort are quite limited . we report the data from a large japanese population . we conducted population screening for 213 unrelated ja...
[ ", pain is frequently viewed in the elderly as a normal process of aging.1 it is estimated that 49%83% of the 1.8 million residents in long - term care have acute or chronic pain , yet the recognition and treatment of pain still presents a challenge.26 recognizing a spectrum of pain behaviors beyond the traditional...	purposeto examine if a concomitant relationship exists between cognition and pain in an elderly population residing in long - term care.background/significanceprior research has found that cognitive load mediates interpretation of a stimulus . in the presence of decreased cognitive capacity as with dementia , the relat...
[ "the objective of this study is to compare the laparoscopy with laparotomy for the treatment of pic with respect to various demographic , perioperative and postoperative parameters . the advantages of laparoscopic surgery include decreased postoperative pain , a short recovery period and improved cosmesis . periton...	objectives : peritoneal inclusion cyst ( pic ) is defined as a fluid - filled mesothelial - lined cysts of the pelvis and it is most frequently encountered in women of reproductive age . the treatment options are observation , hormonal management , imaging - guided aspiration , image - guided sclerotherapy and surgical...
[ "however , these relationships are complex and have yet to be fully clarified . in this study , we evaluated changes in serum leptin levels during pregnancy in overweight / obese and normal - weight pregnant women . in addition , we evaluated the percent and total body weight gain as possible factors influencing th...	backgroundour objective was to evaluate changes in serum leptin levels during pregnancy in overweight / obese and non - obese women and to assess total and percent weight gain during pregnancy as possible factors that influence leptin levels.material/methodsin a prospective study of 42 low - risk pregnant women receivi...
[ "extracellular superoxide dismutase ( sod3 ) is an enzyme known to catalyze dismutation of the highly reactive , superoxide anion into longer - lived and more stable hydrogen peroxide . our results confirm the previously documented anti - inflammatory role of sod3 and additionally , for the first time , we show tha...	extracellular superoxide dismutase ( sod3 ) , an enzyme mediating dismutation of superoxide into hydrogen peroxide , has been shown to reduce inflammation by inhibiting macrophage migration into injured tissues . in inflamed tissues , superoxide is produced by the phagocytic nox2 complex , which consists of the catalyt...
[ "injury to iliac vessels remains exceedingly rare , given its posterior position within the pelvis , representing only 0.4% of vascular injuries . in this case , we highlight a delayed presentation of external iliac artery occlusion secondary to motor - scooter handlebar syndrome , in a paediatric patient . trauma...	arterial occlusion following blunt trauma is an uncommon occurrence . we report an unusual case of delayed external iliac artery occlusion in a young male following blunt abdominal injury . he was successfully treated with thromboendarterectomy and saphenous vein patch repair . there have only been a handful of documen...
[ "this paper will address the most common secondary causes of resistant hypertension ( drug - induced , obstructive sleep apnea , primary aldosteronism , and chronic kidney disease ) , which are frequently encountered in hypertensive patients and are , therefore , the most interesting from the clinical point of view...	resistant hypertension is defined as uncontrolled blood pressure despite the use of three antihypertensive drugs , including a diuretic , in optimal doses . treatment resistance can be attributed to poor adherence to antihypertensive drugs , excessive salt intake , physician inertia , inappropriate or inadequate medica...
[ ", we evaluated the feasibility of coronary intervention using the sheathless gc in patients with small ras . the use of transradial coronary angiography and intervention ( tri ) is increasing because of its low rates of major vascular access - related complications and the potential for early mobilization.1)2 ) a ...	background and objectivestransradial coronary angiography and intervention are increasing in frequency due to lower major vascular access site complications and the potential for early mobilization . however , the small size of the radial artery ( ra ) is a major limitation of this technique . a sheathless guiding cath...
[ "the most widespread type is the alternative splicing at acceptor sites with the pattern nagnag ( n stands for a , c , g , or t , throughout the paper we write t instead of u also when referring to an rna sequence ) ( 12,15,16 ) . as most of the human genes with multiple exons express more than one transcript , alt...	subtle alternative splice events at tandem splice sites are frequent in eukaryotes and substantially increase the complexity of transcriptomes and proteomes . we have developed a relational database , tassdb ( tandem splice site database ) , which stores extensive data about alternative splice events at gyngyn donors a...
[ "associated bicuspid pulmonary valve , aortic valve atresia and heterotaxy have also been described.9 congenital pulmonary vein stenosis is a very rare association with cor triatriatum.10 the morbidity and mortality of cor triatriatum sinistrum is high in those who are symptomatic in infancy . heart defects are the...	five - chambered heart is extremely rare in children . we report a case of asymptomatic five chamber heart detected in infancy . the patient is 2-day - old and managed in a special care baby unit ( scbu ) for neonatal sepsis . during routine follow - up at the age of 1 month , she was found to have an asymptomatic murm...
[ "our aim was to investigate the mirnas ( oncogene or tumor suppressor ) , whose expression might be altered due to inhibition of tgf- signaling pathway . recently , a new layer of cellular mechanisms as microrna ( mirna)-mediated gene expression has been identified that is implicated in the post transcriptional neg...	objective(s):transforming growth factor- ( tgf- ) is involved in colorectal cancer ( crc ) . the sd-208 acts as an anti - cancer agent in different malignancies via tgf- signaling . this work aims to show the effect of manipulation of tgf- signaling on some mirnas implicated in crc.materials and methods : we investigat...
[ "the aim of this study was to synthesize agnps using aqueous leaves extract of p. betle , characterized the agnps and evaluated the antibacterial activity of ag - extract nanoparticles against some gram positive and gram negative bacteria . the betel ( piper betle ) is the leaf belonging to the family piperaceae...	plants or natural resources have been found to be a good alternative method for nanoparticles synthesis . in this study , polyaniline coated silver nanoparticles ( agnps ) synthesized from piper betle leaves extract were investigated for their antibacterial activity . silver nanoparticles were prepared from the reducti...
[ "there are two major categories ( ridden and in - hand ) with in - hand classes placing more \n emphasis on colouration of horses ( 80% of available marks ) . since the national championship \n has the greatest number of exhibitors and the emphasis on colour is greatest for in - hand \n classes , the investigation ...	although various combinations of parental coat colours can produce a palomino foal , examination of records of the british palomino society suggest that many animals registered with the society resulted from matings which maximise the likelihood or even guarantee a palomino foal . when show records were examined ...
[ ", we describe a case of a 73-year - old woman who developed an abdominal wall hematoma , which is a rare but serious complication of a pci via the femoral approach . abdominal wall hematoma is a rare condition that can give rise to an acute abdomen . in this report vascular complications are the most frequent adve...	abdominal wall hematoma is a rare but potentially serious vascular complication that may develop after coronary angiographic procedures . in particular , an oblique muscle hematoma caused by an injury of the circumflex iliac artery is very rare , yet can be managed by conservative treatment including hydration and tran...
[ "for the invasive treatment of symptomatic aortic stenosis several attractive options became available beyond conventional cardiosurgical implantation of stented bioprostheses or mechanical valves . besides stentless prostheses , in particular transcatheter procedures are of growing importance . nevertheless the ...	introductionbiological stented prostheses are currently the main type of prosthetic valve used for aortic valve replacement . the ratio of bioprotheses to mechanical prostheses has switched in the last 15 years ; the percentage of biological prostheses implanted has risen from 30 % to 85 % . moreover the total number...
[ "the above reasons and need , our study was directed to measure the psychological dependence , which is the root cause of high tobacco consumption among the rural population . this study will help and simplify the job of tobacco cessation centers by high - lighting the risk group in relation to high psychological d...	background : in india most of the tobacco cessation centers are concentrating only on urban population , whereas , literature reveals that it is rural population , which shows high frequency of consumption of tobacco . it is well known that high frequency of tobacco consumption is associated with psychological dependen...
[ " while decreases in both breast cancer incidence and mortality have been apparent in recent years , the societal and economic impact of this malignancy continues to be enormous . positive associations between environmental and individual factors and increased risk of breast cancer development have been alleged fo...	in 1976 , sporn has defined chemoprevention as the use of pharmacologic or natural agents that inhibit the development of invasive breast cancer either by blocking the dna damage that initiates carcinogenesis , or by arresting or reversing the progression of premalignant cells in which such damage has already occurred...
[ "mean daily intake of water , wine , beer or cider , and sweet beverages was categorized in the questionnaire into six mutually exclusive levels : none , < 0.5 , 0.5 to 1 , 1 to 1.5 , 1.5 to 2.0 , and > 2 l. in the present analyses , the levels were grouped into three classes : < 0.5 , 0.5 to 1 , and > 1 l. other c...	objectivewater intake alters vasopressin secretion . recent findings reveal an independent association between plasma copeptin , a surrogate for vasopressin , and risk of diabetes.research design and methodsparticipants were 3,615 middle - aged men and women , with normal baseline fasting glycemia ( fg ) , who were rec...
[ "although patients who undergo dialysis suffer from a complex illness , there are compelling reasons to believe that the inadequate removal of organic waste is an important contributing factor to the illness itself . nevertheless , randomized trials examining the impact of increased clearance of traditional uraemic...	although patients undergoing dialysis have a complex illness , there are compelling reasons to believe that the inadequate removal of organic waste is an important contributing factor to the illness itself . this paper focuses on the transport phenomena that occur within a dialyser . an attempt is made to clarify how t...
[ "finally , our study showed that nf - y up - regulated the expression of dmrt7 by binding to two tandem ccaat - boxes in the proximal promoter region of the gene . deletion and site - directed mutagenesis were used to identify regions of the promoter that are required for transcriptional activity . emsa and chip an...	dmrt7 , a member of the dmrt family of genes , is required for spermatogenesis . however , promoter functions of the gene dmrt7 remain unknown . we have cloned and characterized the proximal promoter region of the mouse dmrt7 gene . functional analysis of the 5 ' flanking region by sequential deletion mutations reveale...
[ "primary retroperitoneal germ cell tumors account for approximately 30% of extragonadal germ cell tumors ( egcts ) and for about 10% of all primary malignant retroperitoneal tumors . we report the cases of a 33- and a 39-year - old man presenting with a retroperitoneal extragonadal tumor and bilateral tm without a ...	many studies have demonstrated an association between diffuse bilateral testicular microlithiasis ( tm ) and gonadal and extragonadal germ cell tumors . nevertheless , it is still uncertain whether ultrasound surveillance is really necessary in patients with tm in the absence of other risk factors such as previous test...
[ "administration of intrathecal chemotherapy is generally reserved for patients with leptomeningeal disease and positivity on cerebrospinal fluid ( csf ) testing , although large retrospective series have been equivocal on this topic.22 \n 23 \n surgical resection of cns lymphoma is generally a last resort and only ...	isolated secondary central nervous system lymphoma ( scnsl ) relapse is a rare disease . consequently , standardized treatment regimens have yet to be developed . we present an interesting case of isolated scnsl presenting with altered mental status and panhypopituitarism in a patient at low risk of developing the dise...
[ "we have applied a previously developed method for quantitative determination of the absolute levels of psh , psox , and pssg on all cellular proteins ( including membrane proteins ) in cultured mammalian cells , and combined these data with quantifications of gsh and gssg in the same cells . in this way , we have ...	plasma cells produce and secrete massive amounts of disulfide - containing antibodies . to accommodate this load on the secretory machinery , the differentiation of resting b cells into antibody - secreting plasma cells is accompanied by a preferential expansion of the secretory compartments of the cells and by an up -...
[ "cutaneous horn ( synonyms ; cornu cutaneum : cornu humanum ) is a conical , hyperkeratotic protrusion that often resembles an animal horn . the earliest documented case of cutaneous horn , or cornu cutaneum , was that of an elderly welsh woman in london who was displayed commercially as an anomaly of nature in 158...	cutaneous horn refers to unusually cohesive keratinized material and not a true pathologic diagnosis . though cutaneous horn has been described at various sites , horn over the penis is very rare and represents the most unusual site . the role of chronic irritation , phimosis , surgical trauma and radiotherapy have bee...
[ "high turnover affects the institution 's ability to consistently provide high - quality care and increases institutional costs related to the recruitment , orientation , and lower productivity of newly hired staff . the turnover rate ( employee separations ) of healthcare workers has created a cycle of exhaustion ...	background : the turnover rate ( employee separations ) of healthcare workers has created a cycle of exhaustion and discontent . high turnover affects the institution 's ability to consistently provide high - quality care and increases institutional costs related to the recruitment , orientation , and lower productivit...
[ "we report our clinical experiences using the ascending aorta and aortic arch replacement with perfusion via the brachial and femoral arteries under moderate hypothermia . we tried to use antegrade and retrograde perfusion at the same time , with the aim of avoiding the fatal problems of either method alone . repor...	backgroundselective antegrade perfusion via axillary artery cannulation along with circulatory arrest under deep hypothermia has became a recent trend for performing surgery on the ascending aorta and aortic arch and when direct aortic cannulation is not feasible . the authors of this study tried using moderate hypothe...
[ "this in vitro study is focused on the toxic nature of a volatile smoke component - acrolein on the proliferation and attachment of human gingival fibroblasts . risk assessment has become increasingly important in the prevention of chronic diseases and has recently been applied to oral diseases due to the realizati...	aim : tobacco and some of its volatile and non - volatile components have been found to affect many types of cells including human gingival fibroblasts . the aim of this present study was to estimate the effect of acrolein , a volatile fraction of cigarette smoke on the attachment , proliferation and ultra structure of...
[ "this paper describes the development of a paediatric analgesia and sedation protocol , tailored to the specific setting of the medical research council ( mrc ) paediatric ward in the gambia , west africa . however , it is important to note , that an iterative process was employed beginning with a recognized need t...	despite recent advances in our understanding of paediatric pain and its management , pain continues to be undertreated globally , particularly in children and in low income countries . this article describes the development of a paediatric analgesia and sedation protocol , tailored to the specific setting of the medica...
[ ", we investigated whether rge protects against h. pylori - induced gastric inflammation in mongolian gerbils . korean red ginseng extract ( rge ) inhibits h. pylori - induced oxidative damage in gastric epithelial cells . previously we showed hepatoprotective effects of korean red ginseng in rats and mouse liver...	helicobacter pylori - induced gastric inflammation includes induction of inflammatory mediators interleukin ( il)-8 and inducible nitric oxide synthase ( inos ) , which are mediated by oxidant - sensitive transcription factor nf-b . high levels of lipid peroxide ( lpo ) and increased activity of myeloperoxidase ( mpo )...
[ "we highlight recent findings that indicate the relevance of the cell wall in the interaction with the host immune cells and how this process is essential to prime and develop a protective immune response ( romani , 2004 ) and contributes significantly to the control and pathology of the infection ( casadevall and ...	summaryfungal infections are a serious health problem . in recent years , basic research is focusing on the identification of fungal virulence factors as promising targets for the development of novel antifungals . the wall , as the most external cellular component , plays a crucial role in the interaction with host ce...
[ "this paper discusses findings from various animal models that reveal the role of ps and fad - linked ps mutations in synapse formation and function . mutations in psen1 and psen2 genes , which encode polytopic proteins termed presenilin 1 ( ps1 ) and presenilin 2 ( ps2 ) , respectively , cause autosomal dominant e...	mutations in psen genes , which encode presenilin proteins , cause familial early - onset alzheimer 's disease ( ad ) . transgenic mouse models based on coexpression of familial ad - associated presenilin and amyloid precursor protein variants successfully mimic characteristic pathological features of ad , including pl...
[ "familial hypocalciuric hypercalcemia ( fhh ) is a heterogenic , autosomal dominantly inherited disorder characterized by hypercalcemia with ( relative ) hyperparathyroidism , and hypocalciuria 1 . we now report a family with fhh3 among whom two brothers had ptx performed due to suspected phpt with one of the broth...	key clinical messagefamilial hypocalciuric hypercalcemia type 3 should be considered as differential diagnosis in patients with suspected primary hyperparathyroidism and/or suspected multiple neoplasia syndrome , as correct diagnosis will spare the patients for going through multiple futile parathyroidectomies and for ...
[ "pathblast a server for querying linear pathways within a protein protein interaction ( ppi ) network ( 1)was subsequently extended to allow searching for more general structures ( 2 ) . the torque server implements a novel method for querying protein networks that does not require information on the interconnect...	torque is a tool for cross - species querying of protein protein interaction networks . it aims to answer the following question : given a set of proteins constituting a known complex or a pathway in one species , can a similar complex or pathway be found in the protein network of another species ? to this end , torque...
[ "we present a case of perforating cutaneous metastasis from breast cancer with mucin 1 ( muci ) expression . skin metastases from internal neoplasms are an uncommon clinical finding with an overall incidence of 5.3% and the most common cause is breast cancer with an incidence of 23.9%.1 in general , skin metastases...	breast cancer is the most common cause of cutaneous metastases from internal malignancies . generally , the neoplastic cells are located in the dermis or hypodermis , while a finding of transepidermal elimination on cutaneous metastases is exceptional . in this report we present a patient with perforating cutaneous met...
[ "the aim of this study was to describe how these clinical findings are associated with a decrease in lung function during exacerbations . patients with copd or asthma frequently experience exacerbations of their illness . studies from norway and the uk we also wanted to find out whether the strength of these associ...	backgroundwhen assessing patients with exacerbation of asthma or copd , it may be useful to know the drop in forced expiratory volume in 1 second ( fev1 ) compared with stable state , in particular when considering treatment with oral corticosteroids . the objective of the study was to identify indicators of drop in fe...
[ "we aimed to verify if dlp resulted in significant changes in cerebral blood flow ( cbf ) that could be visualized by tcd . therefore , we identified a group of subjects who developed plph following dlp and compared their pre- and post - puncture blood flow parameters with respective values of plph - free subjects ...	the aim of this study was to verify if diagnostic lumbar puncture ( dlp ) in post - lumbar puncture headache ( plph ) patients is related to significant changes in cerebral blood flow which could be visualized by transcranial doppler ( tcd ) . sixty - six patients were enrolled in this study . tcd was performed 24 h b...
[ "in addition , we have added enrichment profile of various transcription factors obtained from chip - seq data sets . these promoters along with their annotations are provided as a user - friendly database , where each known and chip - seq promoter is linked to a new interface for visualization of enrichment profil...	mpromdb ( mammalian promoter database ) is a curated database that strives to annotate gene promoters identified from chip - seq results with the goal of providing an integrated resource for mammalian transcriptional regulation and epigenetics . we analyzed 507 million uniquely aligned rnap - ii chip - seq reads from 2...
[ "transplantations of mesenchymal stem cells ( mscs ) have shown great potential as a therapeutic agent for the treatment of a range of disorders , including wound healing , and have become the subject of numerous clinical trials . however , whilst the safety of msc transplantation does not seem to be an issue , the...	mesenchymal stem cells ( mscs ) stimulate angiogenesis within a wound environment and this effect is mediated through paracrine interactions with the endothelial cells present . here we report that human msc - conditioned medium ( n=3 donors ) significantly increased eahy-926 endothelial cell adhesion and cell migratio...
[ "preclinical data suggested that the 5-fu plus oxaliplatin combination is more cytotoxic when 5-fu is given as a short exposure , which gives a rationale for exploring the toxicity and efficacy of such protocols in advanced pancreatic cancer . in the current study , we conducted a randomized trial to compare two pr...	objective . comparing activity of 2 regimens combining oxaliplatin to bolus modulated fluorouracil as second line treatment in advanced pancreatic adenocarcinoma pretreated with gemcitabine - containing schedule . methods . forty eight patients with advanced pancreatic adenocarcinoma were randomly assigned to receive e...
[ "primary peritonitis due to s. pyogenes is an unusual condition because streptococcus pyogenes usually causes pharyngitis , erysipelas , and necrotizing fasciitis . in this report , we present the first case to the best of our knowledge of primary peritonitis due to s. pyogenes in korea . primary peritonitis consti...	we describe the first case of primary peritonitis in korea of a healthy person due to streptococcus pyogenes . in the absence of comorbid conditions , such as liver cirrhosis , immunosuppression , or nephrotic syndrome , primary peritonitis is uncommon in a young healthy woman . abdomen computed tomography revealed asc...
[ "carbon monoxide ( co ) is a colorless , odorless , and nonirritant gas that is lighter than air , and it is a product of incomplete combustion of hydrocarbons.1 ) accidental , suicidal or homicidal intoxications with co have a long history . acute co poisoning is an important clinical problem and may lead large pr...	carbon monoxide is a nonirritant , odorless , colorless gas . its effects are prominent in organs most sensitive to oxygen deprivation , such as the heart , brain , and kidney . although less frequently , an association between thromboembolic events and carbon monoxide poisoning has been shown in the literatures . in t...
[ "the syndrome is a combination of features of inherited blistering skin disorders ( e.g. , dystrophic epidermolysis bullosa ) and congenital poikilodermas ( e.g. , rothmund - thompson syndrome ) and should be differentiated due to clinical overlap with hereditary acrokeratotic poikiloderma ( hap ) and dystrophic ep...	kindler syndrome is a rare hereditary disorder , associated with skin fragility . the syndrome involves the skin and mucous membrane with radiological changes . the genetic defect has been identified on the short arm of chromosome 20 . this report describes a 16-year - old patient with classical features like blisterin...
[ "central serous chorioretinopathy ( cscr ) is a chronic idiopathic condition affecting young to middle - aged patients with men affected more commonly than women . nevertheless , it is associated with psychological stress and systemic corticosteroid therapy , which causes hyperpermeability of choriocapillaries , le...	we report a case of central serous chorioretinopathy after rhinoplasty for deviation of the nasal septum in a 23-year - old caucasian man . the patient complained of deterioration of vision in the right eye 4 days after rhinoplasty . at presentation , visual acuity of the right eye was 6/9 with metamorphopsia . fluores...
[ "the aims of the present study are to ascertain the prevalence of cl / p among live births among four provinces in the west and north - west of iran with different ethnic / cultural . the prevalence of cl / p among live births in yazd province ( center of iran ) was 0.86/1000 births . reported the birth prevalence ...	background : one of the most common anomalies in newborn infants is cleft lip and/or cleft palate ( cl / p ) . in spite of several studies about the prevalence of this , no investigation evaluated this prevalence in the west and north - west of iran . with due attention to different ethnic groups in this area , the aim...
[ "based on the previous experimental studies and existing traditional and folk medicine knowledge about some of the cardiovascular beneficial effects concerning rosa damascena l. ( rd ) and quercus infectoria ( qi ) , we have selected these two herbal drugs for the present study . cardiovascular diseases ( cvds ) ac...	according to the use of quercus infectoria ( qi ) and rosa damascena l. ( rd ) for therapeutic purposes and lack of adequate information about their cardiovascular effects , we investigated the cardiovascular indices of rabbits which chronically pretreated with these agents . animal groups were control group ( ctl ) , ...
[ "multicentric reticulohistiocytosis ( mrh ) is a rare multisystem syndrome characterized by polyarthritis and papulonodular skin lesions with typical dermal infiltration of histiocytes and multinucleated giant cells . an association with hyperlipidemia ( 3058% ) , a positive skin tuberculin test ( 1250% ) , systemi...	we report a unique case of multicentric reticulohistiocytosis ( mrh ) associated with liver carcinoma . a 61-year - old man presented with a 4-month history of nonpruritic , generalized , ruby - red papules and nodules , accompanied by fever , joint swelling and difficulty in swallowing . skin histology showed polymorp...
[ "the prognostic parameters ( tumor size , extra - thyroidal extension of ptc , and lymph node metastasis ) were analyzed . among the subtypes of ptc samples in this group , the immunohistochemistry ( ihc ) of the p27 protein expression in the ptc tumor tissue from all 23 cases was analyzed using paraffin - embedded...	backgroundpapillary thyroid carcinoma ( ptc ) is frequently accompanied by lymphocytic thyroiditis ( lt ) . some reports claim that hashimoto s thyroiditis ( the clinical form of lt ) enhances the likelihood of ptc ; however , others suggest that lt has antitumor activity . this study was aimed to find out the relation...
[ "an 83-year - old woman presented with sudden visual loss that had developed in both eyes ( oculus uterque , ou ) the previous day . her visual acuities included perception of light in the right eye ( oculus dexter , od ) and perception of hand motion in the left eye ( oculus sinister , os ) . fundus examination re...	giant cell arteritis ( gca ) is a rare disease among asians . arteritic anterior ischemic optic neuropathy , which accompanies gca , has not yet been reported in koreans . diagnosis of gca is difficult if typical symptoms other than visual loss are absent . here , we report a case of an 83-year - old korean woman prese...
[ "in addition , we characterized the particles with field \n emission gun scanning electron microscopy ( feg - sem ) and tunneling \n electron microscopy ( tem ) , energy - dispersive x - ray spectroscopy ( edx ) , \n x - ray powder diffraction ( xrd ) , and attenuated total reflection fourier \n transform infrared ...	mineral dusts originating from earth s crust are known to be important atmospheric ice nuclei . in agreement with earlier studies , feldspar was found as the most active of the tested natural mineral dusts . here we investigated in closer detail the reasons for its activity and the difference in the activity of...
[ "phylogenetic relationships among genotypes 14 and wild boar , rabbit , rat , avian , bat , and ferret isolates of hepatitis e virus . genomic structure of strains from the united states was similar to that of 2 strains from the netherlands . the entire genome of strains from the united states shared relatively hig...	the complete genome of hepatitis e virus ( hev ) from laboratory ferrets imported from the united states was identified . this virus shared only 82.4%82.5% nt sequence identities with strains from the netherlands , which indicated that the ferret hev genome is genetically diverse . some laboratory ferrets were contamin...
[ "there are a few recent \n reports regarding the effectiveness of extracorporeal shock wave therapy ( eswt ) on \n neurogenic heterotopic ossification ( ho ) in the lower extremity , but to our knowledge , the \n use of eswt or rswt to treat neurogenic ho in the upper extremity has not been reported in \n the liter...	[ purpose ] to report the effects of radial extracorporeal shock wave therapy ( rswt ) on heterotopic ossification ( ho ) . [ subjects and methods ] two cases of neurogenic ho in the upper extremity were administered rswt using the master plus mp 2000 ( storz , tgerwilen , switzerland ) and ultrasonographic guida...
[ "", "while the majority of these injuries occur when a child steps down the stairs , approximately 3 % of injuries will be associated with a caregiver falling while carrying a child . this specific mechanism has been shown to result in injury patterns that are more likely to necessitate hospitalization and more ...	backgroundthe purpose of this study was to describe fractures sustained by children and to analyze the associated costs when a caretaker falls down stairs while holding a child.materials and methodsbetween 2004 and 2012 , 16 children who sustained a fracture after a fall down stairs while being carried by a caregiver w...
[ "prost - type pg derivatives ( that is , pg derivatives other than unoprostone ) are now the drugs of first choice for the treatment of glaucoma because of their potent intraocular pressure ( iop)-lowering activity , the low likelihood of systemic adverse reactions , the once - daily application , and good patient ...	an elevated intraocular pressure ( iop ) is one of the most important risk factors for the development of glaucoma , which causes progressive optic neuropathy . lowering iop is currently the only therapeutic approach to the treatment of glaucoma . tafluprost , a novel prostaglandin analogue , was recently launched onto...
[ "sleep disorders and diurnal sleepiness are frequent in parkinson s disease.1 polysomnography studies have shown rapid - eye - movement ( rem ) sleep dysregulation with rem sleep onset on diurnal naps2,3 and loss of muscle atonia,4 which is defined as excessive amount of sustained or intermittent elevation of subm...	objectivepatients with parkinson s disease frequently complain of sleep disturbances and loss of muscle atonia during rapid - eye - movement ( rem ) sleep is not rare . the orexin - a ( hypocretin-1 ) hypothalamic system plays a central role in controlling rem sleep . loss of orexin neurons results in narcolepsy - cata...
[ "for example : acu - tens ( tens applied to an acupoint ) and \n teas ( transcutaneous electric acupoint stimulation ) that involves any electric current \n applied to acupoints10 . in this study , two different areas of electrodes , 1 cm and 15 cm , \n te5 ( waiguan ) and pc6 ( neiguan ) acupoints . according to...	[ purpose ] this study assesse the effect of low frequency transcutaneous electrical nerve stimulation ( tens ) of thete5 ( waiguan ) and pc6 ( neiguan ) acupoints on cold - induced pain . [ subjects and methods ] forty - eight subjects were divided by convenience into three groups : tens with electrodes of 1 cm...
[ "the aim of this study was to assess the exercise performance of young patients following the repair of tetralogy of fallot and to assess the influence of different variables related to the surgical repair on exercise testing . tetralogy of fallot ( tof ) is the most common form of cyanotic congenital heart disease...	tetralogy of fallot ( tof ) is the most common form of cyanotic congenital heart disease . the aim of this study was to examine the exercise performance of young patients following the repair of tof and to assess the influence of different variables related to the surgical repair on exercise testing . this study was co...
[ "since its original description by mc burney in 1894 , appendectomy has been one of the most common surgical procedures performed by surgeons . in the last decades , laparoscopic appendectomy was an increasingly accepted treatment method for acute appendicitis , particularly for obese or female patients . however ,...	background . natural orifice transluminal endoscopic surgery ( notes ) is a new approach that allows minimal invasive surgery through the mouth , anus , or vagina . objective . to summarize the recent clinical appraisal , feasibility , complications , and limitations of transvaginal appendectomy for humans and outline ...
[ "control evaluation , the odds of having been screened versus not screened in the case group of breast cancer deaths is compared to the same odds in the control group of invited women from whom the cases originate . we compared the mortality rate in the screened ( ms ) with not screened women ( mns ) . we assume th...	residual confounding , after adjustment for age , is the major criticism of observational studies on breast cancer screening effectiveness . we developed realistic scenarios for the prevalence and strength of risk factors on screened and not screened groups , and explored the impact of residual confounding bias . our r...

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