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[ "postoperative pulmonary complications are found to be associated with increased morbidity and mortality following abdominal surgeries . this study aims at evaluating the effect of preoperative counseling regarding postoperative mobilization and its impact on reducing pulmonary complications in a developing world ....	background and objectives . preoperative counseling is effective to foster early postoperative mobilization that reduces pulmonary complications following abdominal surgery . this study aims at evaluating the effect of preoperative counseling regarding postoperative mobilization and its impact on reducing pulmonary com...
[ "the majority of patients diagnosed with incompetent cervix can be treated successfully with a transvaginal cerclage . a select group of patients who have failed the vaginal approach , or have extremely short cervices , anatomically deformed cervix , deeply lacerated cervices , or severely scarred from previous fai...	abdominal cerclages are necessary when the standard transvaginal cerclages fail or anatomical abnormalities preclude the vaginal placement . the disadvantage of the transabdominal approach is that it requires at least 2 laparotomies with significant morbidity and hospital stays . we discuss a case of abdominal cerclage...
[ "the present study was conducted to investigate the efficiency of spiritual group therapy in enhancing patients well - being and spiritual health . the results of a research carried out by meraviglia under the title of effects of spirituality in breast cancer survivors on 84 women aged between 34 and 80 years suf...	cancer is deemed the century s major health problem , and its increasing growth during the last decades has made experts concerned more than ever . of all types of cancer , breast cancer is regarded as the second most common disease among women . the aim of this study was to determine the effectiveness of spiritual gro...
[ "breast cancer , as the most common malignancy , is the major cause of cancer - related deaths of women worldwide [ 1 - 3 ] . age plays a critical role in the incidence of this type of cancer , as it has been found that young breast cancer patients have worse outcomes than older premenopausal or postmenopausal pati...	breast cancer is the most common malignancy , and it is also the major cause of cancer - related deaths of women worldwide . breast cancer treatment involves surgery , chemotherapy , radiation therapy , or combination therapy , and novel strategies are needed to boost the oncologic outcome . the non - metabolizable glu...
[ "even with this sensitive and specific technique , 30 - 60% of patients with encephalitis remain undiagnosed ( 4 ) . encephalitis is one cause of epilepsy in the united states , as the central nervous system ( cns ) trauma ; however , there are 1.4 million cases of head injury in comparison with less than 50000 cas...	background : encephalitis is swelling and inflammation of brain , usually due to viral infection . viral encephalitis symptoms could be fever , headache , altered level of consciousness , and seizures.objectives:the aim of this study was detection of human herpesvirus-6 ( hhv-6 ) dna in cerebrospinal fluid ( csf ) of p...
[ "we review the expression , localization and operation of various functional snare complexes in both murine and human mast cells . we evaluate the published functional data that has been used to implicate specific snares and snare complexes as indispensable mediators of mast cell degranulation . soluble n - ethylma...	mast cell function and dysregulation is important in the development and progression of allergic and autoimmune disease . identifying novel proteins involved in mast cell function and disease progression is the first step in the design of new therapeutic strategies . soluble n - ethylmaleimide - sensitive factor attach...
[ "our primary hypothesis was that a positive fh would be associated with greater rate of atrophy in brain regions known to degenerate early in ad such as the hippocampus , amygdala , entorhinal cortex , and cortical gray matter . the goal of this present analysis was to use adni data to test the effect of fh on long...	a positive family history ( fh ) raises the risk for late - onset alzheimer 's disease though , other than the known risk conferred by apolipoprotein 4 ( apoe4 ) , much of the genetic variance remains unexplained . we examined the effect of family history on longitudinal regional brain atrophy rates in 184 subjects ( 4...
[ "aneurysms of the internal carotid artery ( ica ) in the middle ear are uncommon vascular anomalies and are difficult to detect and treat we describe an asymptomatic case of aneurysm of ica treated successfully by middle ear surgery . the causes of aneurysms are multiple and include atherosclerosis and dysplastic...	middle ear aneurysms are rare and difficult to treat . the case of a 50-year - old female who presented with left otorrhagia caused by an internal carotid aneurysm is reported . she had no medical history of tinnitus , vertigo , otalgia or otorrhea . middle ear surgery was effective in resolving bleeding and did not ca...
[ "one program that is showing great promise in engaging urban teens of various ethnicities in meaningful science activities , including some citizen - science work , and steering them into science , technology , engineering , and mathematics ( stem ) careers is the science career continuum ( scc ) at the chicago bot...	the science career continuum at the chicago botanic garden is a model program for successfully encouraging youth from diverse backgrounds into stem careers . this program has shown that when students are given an opportunity to participate in real scientific research under the mentorship of a caring professional over m...
[ "recently , we showed that kca1.1 channels also form a physical complex with low voltage - activated ( lva ) cav3 t - type ca channels , as shown through coimmunoprecipitation . calcium - dependent potassium ( kca ) channels are known to form complexes with voltage - gated calcium ( ca ) sources . these interaction...	high voltage - activated ( hva ) cav channels form complexes with kca1.1 channels , allowing reliable activation of kca1.1 current through a nanodomain interaction . we recently found that low voltage - activated cav3 calcium channels also create kca1.1-cav3 complexes . while coimmunoprecipitation studies again support...
[ ". however , the ligaments injured vary greatly from one patient to another due to discrepancy in the magnitude of trauma , direction of the violent forces and position of the affected limb at the time of injury.56 additionally , each patient who suffers from multiple ligament injured knee has his own individual ch...	background : multiple ligament injured knee is generally described for a scenario when at least 2 of the 4 major ligaments are ruptured . the most effective treatment for these injuries remains controversial . this study presents the clinical outcome of 3 surgical strategies based on personalized treatment.materials an...
[ "the primary objectives in rehabilitating the maxillofacial defect patients are to restore the function of mastication , deglutition , speech , and to achieve normal orofacial appearance . the case reported in this article is a large facial defect resulted from rare severe fungal infection mucormycosis . the defect...	rehabilitation of maxillofacial defect patients is a challenging task . the most common prosthetic treatment problem with such patients is , getting adequate retention , stability , and support . in cases of large maxillofacial defect , movement of the prosthesis is inevitable . the primary objectives in rehabilitating...
[ "corneal lamellar keratoplasty ( lk ) is a surgical technique that allows preserving healthy portions of the cornea while selectively replacing the dysfunctional segments . deep anterior lamellar keratoplasty ( dalk ) is a surgical technique that is considered the best for treating the patients with anterior layer ...	descemet membrane endothelial keratoplasty ( dmek ) is a corneal surgical technique which selectively replaces the damaged posterior part of the cornea with a healthy donor graft retaining the rest of the tissue intact . there is a need to validate and standardize the donor tissue before grafting due to certain issues ...
[ "hence , the aim of our study was an evaluation of the periodontal parameters ; pd , and al , on the distobuccal aspect of the second molar after surgical extraction of the impacted third molar . there is controversy about the incidence of periodontal defect at the distal aspect of the second molars after surgical ...	background : several conflicting findings have been published in the previous literature regarding the effects of impacted third molar surgery on the periodontal parameters of the adjacent second molar ; some authors have shown improvement of periodontal health distal to the adjacent second molar , whilst others have d...
[ "autologous peripheral blood hematopoietic cell transplantation ( auto - pbhct ) is a well - established therapeutic option for patients with a variety of hematologic malignancies . herein we report our experience from two north american transplant centers in a series of patients who received plerixafor salvage whi...	the combination of filgrastim ( g - csf ) and plerixafor is currently approved for mobilizing peripheral blood progenitor cells in patients with non - hodgkin lymphoma and multiple myeloma undergoing autologous peripheral blood hematopoietic cell transplantation . however , chemotherapy and g - csf - based mobilization...
[ "we report on a large right middle cerebral artery ( mca ) aneurysm , which induced subarachnoid hemorrhage ( sah ) after rupture and showed spontaneous occlusion after a wrapping operation . the characteristics and causes of the aneurysm and possible spontaneous cure many studies on unruptured aneurysms have repor...	there are few observation papers regarding the natural history of an aneurysm . we report on a case of a completely occluded middle cerebral artery ( mca ) aneurysm . a 47-year - old female patient presented with a headache and was diagnosed with rupture of a right mca aneurysm . due to a high risk of direct neck clipp...
[ "", "we studied 27 patients in stable neuromuscular condition who initially received niv to manage fatal arf to identify differences in factors immediately before the onset of arf among patients who receive continuous niv support , patients who are switched from niv to invasive ventilation , and patients in whom ...	if invasive ventilation can be avoided by performing noninvasive mechanical ventilation ( niv ) in patients with acute respiratory failure ( arf ) , the disease can be effectively managed . it is important to clarify the characteristics of patients with neuromuscular diseases in whom initial niv is likely to be unsucce...
[ ". a better understanding of metallic hardware failure during removal procedures may help surgeons in the preoperative planning stages of these cases , in terms of surgical tool selection and staff availability . the distal humerus of the elbow is unique in that is has a high ratio of cortical to cancellous bone . ...	a retrospective review of 21 patients that underwent bone screw removal from the elbow was studied in relation to the type of metal , duration of implantation , and the location of the screws about the elbow . screw failure during extraction was the dependent variable . five of 21 patients experienced hardware failure ...
[ "the h37rv - atcc 25618 ( susceptible to all drugs ) , atcc 35822 ( resistant to inh ) , atcc \n 35838 ( resistant to rif ) and atcc 35820 ( resistant to str ) strains were used for quality \n control . nineteen isolates were multidrug - resistant ( mdr ) , eight \n isolates were only resistant to inh and the remai...	early detection of drug resistance in mycobacterium tuberculosis isolates allows for earlier and more effective treatment of patients . the aim of this study was to investigate the performance of the malachite green decolourisation assay ( mgda ) in detecting isoniazid ( inh ) and rifampicin ( rif ) resistance in...
[ "this paper presents characteristics of ethoxyquin with regard to its properties , metabolism , toxicity , possible carcinogenicity , and antioxidant activity . the use of ethoxyquin is not permitted in foods intended for human , except preserving powdered paprika and chili colour and using it as an antiscald agent...	ethoxyquin ( eq , 6-ethoxy-1,2-dihydro-2,2,4-trimethylquinoline ) is widely used in animal feed in order to protect it against lipid peroxidation . eq can not be used in any food for human consumption ( except spices , e.g. , chili ) , but it can pass from feed to farmed fish , poultry , and eggs , so human beings can ...
[ "seizures are the most common neurological events of childhood with approximately 35% of children experiencing a seizure at some point in their lives 25% of whom subsequently go on to develop epilepsy . comprises of children and adolescents . intractable epilepsy is defined as a failure to respond to at least two...	objectives : to study the outcome of disconnective epilepsy surgery for intractable hemispheric and sub - hemispheric pediatric epilepsy . methods : a retrospective analysis of the epilepsy surgery database was done in all children ( age < 18 years ) who underwent a peri - insular hemispherotomy ( pih ) or a peri - ins...
[ "mutations in codons 12 and 13 of kirsten rat sarcoma viral oncogene homolog ( kras ) and b - raf murine sarcoma viral oncogene homolog b1 ( braf ) genes are frequently present in tumors of patients with metastatic colorectal cancer ( crc ) ; they are observed in 30 - 45% and 5 - 20% of cases respectively 1 . rarel...	kras mutations occur frequently in colorectal cancers ( crc ) and predict lack of response to anti - epidermal growth factor receptor ( egfr ) monoclonal antibody therapy . crc braf mutations , most commonly at v600e , occur less than 10% of the time , and occur usually in kras wild - type tumors , and more frequently ...
[ "apolipoprotein ( apo ) a - v - is an enigmatic modulator of plasma triacylglycerol ( tg ) homeostasis . genome wide association studies ( gwas ) have identified apoa5 as a determinant of plasma tg concentrations . apoa - v is expressed solely in the liver and , following secretion , circulates at extremely low con...	abstractapolipoprotein ( apo ) a - v is a novel member of the class of exchangeable apo 's involved in triacylglycerol ( tg ) homeostasis . whereas a portion of hepatic - derived apoa - v is secreted into plasma and functions to facilitate lipoprotein lipase - mediated tg hydrolysis , another portion is recovered intra...
[ "twenty - two patients had been treated with copper chelators , d - penicillamine ( n = 16 ) , or trientine ( n = 6 ) ( median duration of treatment : 6 years , range : 0.5 - 12 years ) at the time of mr imaging . the two readers evaluated the mr images for ( a ) the presence and pattern of intrahepatic nodules , (...	objectiveto determine whether there is a correlation between liver mr findings and the clinical manifestations and severity of liver dysfunction in patients with wilson 's disease.materials and methodstwo radiologists retrospectively evaluated mr images of the liver in 50 patients with wilson 's disease . the instituti...
[ "the truth is that most medical breakthroughs have ultimately come from basic research , and i think that we as scientists need to do a better job of telling these success stories . it s a beautiful example of something entirely unanticipated coming out of left field . that s why it s important to maintain funding ...	the genetics society of america medal is awarded to an individual for outstanding contributions to the field of genetics in the past 15 years . recipients of the gsa medal are recognized for elegant and highly meaningful contributions to modern genetics . the 2014 recipient , angelika b. amon , has uncovered key princi...
[ "we submitted each pulmonary nodule individually , as if it were a solitary metastasis , as well as all the nodules of the same patient combined , to both the who and the recist criteria and compared the response evaluations in each setting . the selection of one or a few nodules , instead of including all identifi...	objective : with the introduction of cross - sectional imaging methods the number of lesions per patient that can be evaluated is frequently large and most oncologists and study protocols use only one lesion or a few representative lesions to evaluate chemotherapy response . intra - patient response variability can th...
[ "lumbar degenerative kyphosis ( ldk ) is a common cause of lumbar spinal deformity in asian \n women aged 40 years and older . the ability of nmes to stimulate the deep lumbar stabilizing muscles of ldk \n patients was investigated , using real - time ultrasound imaging ( rusi ) . however , no report to date has b...	[ purpose ] to investigate the effectiveness of three different neuromuscular electrical stimulation ( nmes ) protocols for the deep lumbar stabilizing muscles of patients with lumbar degenerative kyphosis ( ldk ) . [ subjects and methods ] twenty patients with ldk were recruited . three stimulation protocols wer...
[ "many randomized controlled trials ( rcts ) about the role of isoflavones in men with pca have been developed ; however , these results are inconsistent . in this study , we review some critical issues involving the effects of isoflavones on psa , sex steroid hormone levels and risk of pca , and the difference in c...	objective : the purpose of this review is to discuss some critical issues of isoflavones protective against the development of prostate cancer ( pca).data sources : data cited in this review were obtained primarily from pubmed and embase from 1975 to 2015.study selection : articles were selected with the search terms ...
[ "the spinal dural arteriovenous fistula ( sdavf ) is the most common type of spinal vascular malformation , but it is rare condition in overall incidence561013171820 ) . we present a patient with sdavf and a history of paraparesis during spinal angiography who was treated successfully using stereotactic radiosurger...	the spinal dural arteriovenous fistula ( sdavf ) is rare , presenting with progressive , insidious symptoms , and inducing spinal cord ischemia and myelopathy , resulting in severe neurological deficits . if physicians have accurate and enough information about vascular anatomy and hemodynamics , they achieve the good ...
[ "incompetence in locating , cleaning and shaping or obturating the complete root canal system causes primary and post - treatment infections which often lead to endodontic treatment failures . however , the most significant reason for the root canal treatment failure is insufficient knowledge about the root canal m...	it is important to assess the root canal morphology and its variations before initiating the endodontic procedure . this is because the inability to clean the complete root canal system forms the seat for the persistent infection which ultimately leads to endodontic treatment failure . this case reports the use of dent...
[ "thus the aim of the present study was to assess the knowledge , attitude and practice regarding the risk of hiv infection among dental students after an accidental needlestick injury and to make relevant suggestions . there is confusion regarding correct responses to such accidents both at the administrative level...	background : injuries from occupational accidents are associ - ated with agents of biological risk , as they are the gateway to serious and potentially lethal infectious diseases that can be spread by contact between people . several studies have demonstrated that dental students are among the most vulnerable to blood ...
[ "the reported studies focus on both routine clinical isolates and specific genetically modified species such as p. aeruginosa . to date is the initial measure of the potential of a compound , and for the three examples of siderophore agents , in vitro data are presented in tables 2 and 3 . , there have been no hea1...	antibiotic resistance has been emerged as a major global health problem . in particular , gram - negative species pose a significant clinical challenge as bacteria develop or acquire more resistance mechanisms . often , these bacteria possess multiple resistance mechanisms , thus nullifying most of the major classes of...
[ "phylogenetic trees of the 7 gene segments of d / bovine / france/2986/2012 influenza virus at the nucleotide level . in addition , the splicing pattern of the matrix gene segment and the reduced 5-n - acetyl binding pocket in the hemagglutinin - esterase ( he ) protein of d / bovine / france/2986/2012 was similar ...	a new influenza virus , genus d , isolated in us pigs and cattle , has also been circulating in cattle in france . it was first identified there in 2011 , and an increase was detected in 2014 . the virus genome in france is 94%99% identical to its us counterpart , which suggests intercontinental spillover .
[ "ventriculo - peritoneal ( vp ) shunting is the preferred and most successful method for managing congenital hydrocephalus . an uncommon but recognized complication is formation of an abdominal pseudocyst , with cerebrospinal fluid ( csf ) collecting and being poorly absorbed or not absorbed across the serosa . exp...	insertion of a ventriculo - peritoneal ( vp ) shunt is the most common operative procedure for the treatment of hydrocephalus in children . of the several causes of shunt malfunction , cerebrospinal fluid ( csf ) pseudocyst is relatively uncommon . there are several modalities to treat a csf pseudocyst . laparotomy is ...
[ "the study evaluated the concentration of 25(oh)d3 and the indices of calcium phosphate metabolism depending on the sex , number of relapses , degree of motor disability and the applied treatment at different stages of relapsing remitting ms ( rrms ) . to provide complex medical care , it is important to determin...	introduction and objectivesthe purpose of this study was to evaluate the concentration of 25-hydroxycholecalciferol and parameters of calcium phosphate metabolism at different periods of relapsing remitting multiple sclerosis ( rrms).materials and methodsforty - five patients , residents of poland ( 4950 , n ) , were...
[ "the aim of the present study was to determine the incidence of severe rop requiring laser treatment and the overall incidence of rop , and to evaluate the risk factors for developing severe rop requiring laser treatment in elbw infants in turkey . recent studies report many systemic risk factors ( respiratory dist...	backgroundthe aim of this study was to identify the incidence of severe retinopathy of prematurity ( rop ) requiring laser treatment and the overall incidence of rop in extremely low birth weight ( elbw ) infants , and to evaluate the associated risk factors for developing severe rop in elbw infants in turkey.material/...
[ "we hypothesized that subjects who received the \n neurocognitive protocol would show greater improvements on motor , sensory and cognitive \n functional aspects when compared with those treated with a conventional protocol , and these \n positive changes would also demonstrate clinical and significant improvements...	[ purpose ] this study aims to describe a protocol based on neurocognitive therapeutic exercises and determine its feasibility and usefulness for upper extremity functionality when compared with a conventional protocol . [ subjects and methods ] eight subacute stroke patients were randomly assigned to a conventio...
[ "readings in micromoles per liter obtained from the glucose analyzer were then converted to micromoles per gram of tissue based on the total volume of homogenate and the corresponding tissue weight ( early - onset uncontrolled diabetic mode [ with or without phlorizin ] ; whole - body and hypothalamic sustained hyp...	objectivecirculating glucose inhibits glucose production in normal rodents and humans , but this glucose effectiveness is disrupted in diabetes due partly to sustained hyperglycemia . we hypothesize that hyperglycemia in diabetes impairs hypothalamic glucose sensing to lower glucose production , and changes of glucose ...
[ "the aim of this work is to test the efficiency of our light - activated ds - dna - cleavers towards intracellular dna using single cell gel electrophoresis assay which can measure dna damage in individual eukaryote cells [ 2125 ] . the cleaved dna fragments are able to migrate out of the cell under an electric fie...	previously , we reported the design and properties of alkyne c - lysine conjugates , a powerful and tunable family of dna cleaving reagents . we also reported that , upon photoactivation , these molecules are capable of inducing cancer cells death . to prove that the cell death stems from dna cleavage by the conjugates...
[ "patients with any substance dependence were recruited from outpatient setting at their first contact at ddtc from 1 january , 2010 - 31 december , 2010 . a cross - sectional design was employed and written informed consent was obtained from the patients taken up for the study . the study was conducted at the drug ...	background : substance abuse , alcohol in particular , is associated with increased risk of diabetes and metabolic syndrome ( ms ) . the relationship between the substance abuse and ms is complex and the literature is sparse.objectives:the present research was aimed to study the prevalence and predictors of ms among ou...
[ "as there is scant evidence regarding the assessment of hospital teams in iran and due to researches on team performance in non - hospital sectors in other countries , we decided to conduct this research because knowing the attitudes of team members in an iranian context can have a significant effect on managing he...	introduction : patients health and safety is not only a function of complex treatments and advanced therapeutic technologies but also a function of a degree based on which health care professionals fulfill their duties effectively as a team . the aim of this study was to determine the attitude of hospital committee mem...
[ "present study was designed to assess whether srage levels alter in prediabetes and correlate with ir and beta cell function in prediabetes and newly diagnosed t2 dm . the ir and beta cell dysfunction are two core defects of t2 dm , and the prediabetes is a category of increased risk of developing t2 dm in subjec...	this study examined whether circulating levels of soluble receptor for advanced glycation end products ( srage ) alter in prediabetes and correlate with insulin resistance ( ir ) and beta cell function in prediabetes and newly diagnosed type 2 diabetes mellitus ( t2 dm ) . subjects without previous history of diabetes ...
[ "radicular low back pain is one of the most common medical problems that cause decreased work competence and a heavy cost . there is little research comparing the accuracy of mri with electrodiagnostic methods in the diagnosis of lower extremity radicular pain ; therefore , the aim of this study was to do this in r...	introduction . radicular low back pain is one of the most common medical problems . the aim of this study was to evaluate the diagnostic accuracy of mri and electrodiagnosis in lower extremity radicular pain in relation to history and clinical findings . methods . in this cross - sectional study , we studied 165 sciata...
[ "the standard treatment of choice is anterior cervical discectomy and fusion ( acdf ) . although most patients wish to treat both the posterior neck pain and associated arm pain , some patients wish to be treated with less invasive methods , even though some tolerable symptoms may persist , due to their social / ph...	anterior cervical discectomy and fusion ( acdf ) is currently the standard treatment for cervical disc disease . some patients wish to be treated with a less invasive method , because of their social / physical situations . here we present one method of treatments for socially / physically active patients . three patie...
[ "this article evaluates the prevalence of ntis and describes the relationship between ntis and frailty . we observe a progressive reduction in serum triiodothyronine ( t3 ) concentrations , while the levels of thyroxine ( t4 ) and thyroid stimulating hormone ( tsh ) do not change significantly.9 these values are su...	introductionfrailty is associated with a functional decline of multiple physiological systems , of which they may be a cause or consequence . the objective of the study was to evaluate the prevalence of thyroid hormone modifications in elderly frail subjects and its relationship with frailty.study population and method...
[ "nedd41 is a positive regulator of neurite growth and may have additional roles in regulating axon pathfinding , spine formation , and synaptic plasticity . nedd41 is a positive regulator of neurite growth and may have additional roles in regulating axon pathfinding , spine formation , and synaptic plasticity . \n ...	we found recently that mtorc1 regulates the biosynthesis of the ubiquitin e3 ligase nedd41 , but not the close homolog nedd42 . this regulatory process plays a key role in promoting neurite growth in neurons of the mammalian central nervous system . the molecular mechanism underlying this rather specific regulation lik...
[ "hypothermia defined as a core body temperature < 35 can be a life - threatening emergency , especially in cold winter climates , but can be used therapeutically . therapeutic hypothermia ( th ) it is not pathognomonic of hypothermia , but usually occurs in patients with a core temperature < 32 and the magnitude of...	therapeutic hypothermia ( th ) has been used to protect neurological functions in cardiac arrest patient . although osborn wave is not pathognomonic of hypothermia , it is a well - known electrocardiogram finding of hypothermic patients . the cellular and ionic mechanisms of the osborn wave have been suggested , and it...
[ "recent genome - wide association analyses have identified multiple loci that are associated with af.1,2 one of the strongest associations with af , confirmed by validation studies , involves two non - coding single nucleotide polymorphisms ( snps ) on chromosome 4q25 ( rs2200733 and rs10033464).2 polymorphisms at ...	aimsrecent studies have shown that several genetic variants near the pitx2 locus on chromosome 4q25 are associated with atrial fibrillation ( af ) . however , the mechanism that mediates this association remains unclear . basic murine studies suggest that reduced pitx2 expression is associated with left atrial dilatati...
[ "multiple studies have demonstrated significantly better outcomes with multimodality approaches compared to surgery or radiotherapy alone , emphasizing the fact that completion of the planned treatment protocol plays an important role in determining the outcomes of the patients . the purpose of the present audit is...	background : the aim of this study is to identify the factors responsible for interruption of planned treatment in patients of carcinoma mid - thoracic esophagus and also discuss the strategies for improving treatment completion rates.materials and methods : patients with nonmetastatic mid - thoracic esophageal cancer ...
[ "response curve for iop lowering , with an optimal concentration between 0.25% and 0.5%.32 removal of bak from 0.5% timolol ophthalmic solution formulations could reduce timolol bioavailability enough to achieve a concentration that optimizes intraocular efficacy.32 this literature review aims to explain the findin...	purposemany patients with glaucoma require combination therapies to achieve target intraocular pressure ( iop ) and preserve visual function . ocular hypotensives often contain a preservative ( eg , benzalkonium chloride [ bak ] ) , but preservative - free ( pf ) formulations have been developed for patients with sensi...
[ "we report a case of late onset angioma serpiginosum localised to the breast , an unusual site . angioma serpiginosum is a benign vascular nevoid disorder with proliferation and ectatic dilatation of capillaries in the papillary dermis . most cases are sporadic but familial cases suggesting an autosomal dominant in...	angioma serpiginosum is a cutaneous vascular nevoid disorder that presents as red , nonblanchable and grouped macules distributed in a serpiginous pattern and resembles purpura . it usually begins in childhood and commonly affects the lower limbs and the buttocks . late onset of the lesions is unusual . we report a 46-...
[ "we report a case of acute cmv colitis in an immunocompetent adult that was complicated by vascular thrombosis and pulmonary embolism . symptoms , when they occur , include fever , cervical lymphadenitis , and arthralgia.3 rarely , acute cmv infection may be complicated by pneumonia , colitis , myocarditis , perica...	acute cytomegalovirus ( cmv ) infection occurs commonly in immunocompromised and immunocompetent patients , but is usually asymptomatic in the latter . vascular events associated with acute cmv infection have been described , but are rare . hence , such events are rarely reported in the literature . we report a case of...
[ "insulinoma is a rare neuroendocrine tumor of the pancreas , accounting for 2% of all pancreatic tumors . we report a case of an insulinoma in an 11-year - old child who subsequently developed multifocal nodular lesions of the liver after resections of the insulinoma . its occurrence is 1:100,000 and it is more com...	insulinoma , which arises from insulin - producing pancreatic beta cells , is a rare tumor in children . only 5%-10% of insulinomas are malignant and undergo metastasis . we report a case of an 11-year - old girl who experienced hypoglycemia - related seizures induced by an insulinoma ; after resection of the primary t...
[ "prostate cancer is the most common cancer in males , followed by lung and colorectal . for women cancer is the second leading killer in the usa , accounting for 25% of all deaths . diet and inactivity play a major role in the development of these common cancers . in order to understand how lifestyle changes might ...	cancer is the second leading cause of death in the usa and an abundance of evidence suggests that lifestyle factors including smoking , the typical high - fat , refined - sugar diet and physical inactivity account for the majority of cancer . this review focuses on diet and inactivity as major factors for cancer promot...
[ "( family saxifragaceae ) , a high value plant of the sikkim himalaya , has been investigated for antioxidant , antimicrobial activity and bioactive compounds . extensive investigation of medicinal plants for biological activities and bioactive compounds is the crucial and the foremost step in development of effect...	bergenia ciliata sternb . , commonly known as paashaanbhed , is a well known herb of sikkim himalaya with various pharmaceutical properties . however , scientific exploration of b. ciliata , growing in the sikkim himalaya , for phytochemicals and pharmacological properties is in infancy . with this view , the present ...
[ "dyskeratosis congenita ( dc ) is a rare multisystem disorder first described in the early 20 century ( 1906 ) ; it is also known as zinsser - engman - cole syndrome.1 it is characterised by the classic triad of mococutaneous pigmentary disorder , nail dystrophy and oral leukoplakia seen in 89% , 80% and 45% of cas...	dyskeratosis congenita is a rare hereditary disease . it mainly affects males and manifest between 5 years and 12 years . its classic manifestation consists of skin pigmentary changes , nail dystrophy , oral leukoplakia , bone marrow failure and predisposition to malignany . we report the case of a 9-year - old boy who...
[ "we present a case of ttp developed after a htr in the setting of cardiac bypass surgery . secondary thrombotic ttp is a life - threatening condition and is characterized by an aggressive course , it requires prompt treatment at the outset . in case of delayed or inadequate treatment mortality rate may be close to ...	the triggers of secondary thrombotic thrombopcytopenic purpura ( ttp ) include drug toxicity , radiation and high - dose chemotherapy , angioinvasive infections , surgery and acute graft versus host disease . ttp secondary to surgery have been reported in a number of cases . most of the cases have been occurred after o...
[ "transurethral resection of bladder tumor ( turbt ) is well - established modality for treating non - muscle - invasive bladder cancer . , we demonstrate the easy resection technique for superficial bladder tumors that we have termed the \" grasp and bite \" turbt technique and compare it with conventional turbt . ...	purposetransurethral resection of bladder tumor ( turbt ) can be a challenging procedure for an inexperienced surgeon . we suggest an easy technique for turbt , which we have named the " grasp and bite " technique . we describe this technique and compare its effectiveness and safety with that of conventional turbt.mate...
[ ", medicinal plants are used traditionally to treat various ailments . among the promising medicinal plants , ziziphus mucronata(zm ) in the family ramnaceae the use of natural remedies has been recently observed to be a good means of curbing oxidative stress by boosting the natural antioxidant defence system . in ...	objective : the study was carried out to evaluate the hepatoprotective and antioxidant potential of ziziphus mucronata ( zm ) fruit extract.methods:the different types of fruit extract were prepared by soaking the dry powdered fruit in different solvents followed by rotary evaporation . each extract was tested for its ...
[ "once considered diseases of affluence , the prevalence of non - communicable chronic health conditions , including overweight , has increased substantially in many low - and middle - income countries ( 13 ) . as chronic conditions increase in these countries , we use china as a case study to investigate the socia...	objectivewe test whether a disparity by socioeconomic status ( ses ) ( represented by educational attainment ) in overweight has emerged among men or women during a recent 17 year period in china.methodsdata from the china health and nutrition survey ( chns ) , a panel study including 7,314 women and 6,492 men , are us...
[ "stenosis was observed in the first and third finger artery in the area of radial artery and palmer arch , and greater than 90% stenosis was also observed in distal ulnar artery . at the time of referral , after the spinal cord stimulation insertion , the ulcers on both hands began gradual recovery and were complet...	buerger 's disease ( thromboangiitis obliterans ) is known as a segmental inflammatory vasculitis that involves the small - sized and medium - sized arteries , veins , and nerves . most effective treatment for buerger 's disease is smoking cessation . except for the cessation of tobacco use , surgical revascularization...
[ "the purpose of this article is to outline the present status of simulation related to wounds , in terms of their creation and management . pari passu with the progress of science in medical education , simulation in medical education is also progressing in leaps and bounds . simulation in relation to wounds can be...	simulation in medical education is progressing in leaps and bounds . the need for simulation in medical education and training is increasing because of a ) overall increase in the number of medical students vis - - vis the availability of patients ; b ) increasing awareness among patients of their rights and consequen...
[ "the purpose of this review is to present an overview of the current disease status with respect to the prevalence , mortality rate , socioeconomic burden , quality of life and the treatment patterns of asthma in korea , to identify barriers to improvements in asthma care and to provide recommendations for action a...	a systematic review of english and korean articles published between 1990 and 2004 and a search of database and various online resources was conducted to determine the prevalences , mortality rates , socioeconomic burden , quality of life , and treatment pattern of asthma in korean adults and children . asthma morbidit...
[ "asthma in adults is a heterogeneous disease usually characterized by chronic airway inflammation with hyperresponsiveness of airways to various stimuli . , we believe that the spanish experience may be useful and potentially applicable to other settings , in particular with similar health care systems . however , ...	this paper , developed by consensus of staff physicians of accredited asthma units for the management of severe asthma , presents information on the process and requirements for already - existing asthma units to achieve official accreditation by the spanish society of pneumology and thoracic surgery ( separ ) . three ...
[ "these diseases may increase the likelihood of cardiovascular events ( 18 ) and may predispose children to the development of cardiomyopathy . based on these considerations , we reviewed the published literature on endothelial function in pre - pubertal children to evaluate the endothelial function in pre - puberta...	although it is known that obesity , diabetes , and kawasaki 's disease play important roles in systemic inflammation and in the development of both endothelial dysfunction and cardiomyopathy , there is a lack of data regarding the endothelial function of pre - pubertal children suffering from cardiomyopathy . in this s...
[ ", it is proposed that liquid chromatography with fluorescence ( lc - fl ) seems to be useful for the determination of acetone in the saliva . in this paper , we present a rapid and simple hplc technique using 2,4-dnph as a derivatizing reagent for quantitative determination and metabolomic research of acetone in b...	using high - performance liquid chromatography ( hplc ) and 2,4-dinitrophenylhydrazine ( 2,4-dnph ) as a derivatizing reagent , an analytical method was developed for the quantitative determination of acetone in human blood . the determination was carried out at 365 nm using an ultraviolet - visible ( uv - vis ) diode...
[ "this situation , in which obesity seems to protect patients with acute coronary syndrome ( acs ) , has been called the obesity paradox and has been described in other facilities . , the goal of this study is to determine the relationship between bmi and intrahospital mortality in patients admitted consecutively ...	although obesity is a well - established cardiovascular risk factor , some controversy has arisen with regard to its effect on hospital mortality in patients admitted for acute coronary syndrome . methods . clinical and anthropometric variables were analyzed in patients consecutively admitted for acute coronary syndrom...
[ ", we evaluated the candidial / streptococci carriage and the various species of candida / streptococci isolated from the down syndrome patients and correlated it with normal oral micro flora from health subjects . down syndrome ( trisomy 21 ) is the most common and best known of all malformation syndromes . it is ...	aim : we aimed to evaluate the prevalence of candida and streptococci species in the oral cavity of down syndrome patients.materials and methods:50 children / adolescents with down syndrome with a karyotype of 47 xx , 21 + ( female ) and 47 xy , 21 + ( male ) , and 50 normal children / adolescents were included in our ...
[ "the goal of this study was to determine a reliable association between changes in cvp and pvp in patients with burns and to assess the long - term correlation in varied hemodynamic status during the first 10 h. although controversy still exists concerning the role of peripheral veins and their contribution to the ...	background : optimizing cardiovascular function to ensure adequate tissue oxygen delivery is a key objective in the care of critically ill patients with burns . hemodynamic monitoring may be necessary to optimize resuscitation in serious burn patients with reasonable safety . invasive central venous pressure ( cvp ) mo...
[ "schizophrenia is a chronic disorder with serious physical , social , and economic consequences , with an impact on public health that has been unappreciated . thus , it is a devastating illness that reflects in the productivity of individuals affected by it and requires permanent spending with hospitalizations , t...	antipsychotics have provided a great improvement in the management of people with schizophrenia . the first generation antipsychotics could establish the possibility of managing many psychotic subjects in an outpatient setting . with the advent of the second ( sga ) and third generation antipsychotics ( tga ) , other p...
[ "the objective of this study is to compare iodine clearance following iodinated contrast administration in thyroidectomised thyroid cancer patients and euthyroid individuals . the duration of time required for body iodine stores to return to normal following iodinated contrast administration has not been well studi...	purpose . to compare iodine clearance following iodinated contrast administration in thyroidectomised thyroid cancer patients and euthyroid individuals . methods . a convenience population ( 6 thyroidectomised thyroid cancer patients and 7 euthyroid controls ) was drawn from patients referred for iodinated contrast - e...
[ "we sought to determine knowledge and attitudes of hpv and the vaccine in the bahamas and determine whether differences exist between different cultures of african descent . , we reported that the general population was aware of hpv as well as the hpv vaccine ; however , the benefits of the vaccine to the study pop...	objective . to compare knowledge and attitudes of human papillomavirus ( hpv ) and the vaccine between different cultures of african descent . methods . a cross - sectional survey of 555 african - americans and afro - caribbeans residing in the us and the bahamas ( bhm ) was conducted . results . general knowledge abou...
[ "( 1 ) . in this report of a 2009 national conference designed to develop a blueprint for real change in biology education , the ability to understand the relationship between science and society is identified as a core competency in the practice of science with one example being evaluating ethical implications ...	with the rise of biomedicine and biotechnology , there has been a corresponding growth in the need for better understanding of consequent ethical questions . increasingly , biologists are being asked not only to offer technical clarifications but also to venture ethical opinions , for which most feel poorly equipped . ...
[ "real - time monitoring of the circadian gene expression was performed using rat-1 cells expressing a luciferase reporter under the control of the upstream region of bmal1 gene . the substrate proteins , gst - sp , mbp - nt , gst or mbp ( each 100 ng ) were prepared as described previously . the in vitro kinase as...	molecular oscillation of the circadian clock is based on e - box - mediated transcriptional feedback loop formed with clock genes and their encoding products , clock proteins . the clock proteins are regulated by post - translational modifications such as phosphorylation . we investigated the effects of a series of kin...
[ "meanwhile , after four decades of development , the clinical application of allogeneic hematopoietic stem cells in transplantation for the treatment of congenital bone marrow diseases was moving ahead reasonably briskly ( sans gigantic regulatory hurdles ) . both the science and the regulatory apparatus seemed to ...	though the field has moved with glacial speed , gene therapies have been carried out successfully in patients with bone marrow disorders including immune deficiencies . the field may be poised to move forward more rapidly , but many barriers have yet to be surmounted .
[ "periodontal disease is a multifactorial disease , characterized by periodontal pocket formation , loss of clinical attachment , and alveolar bone resorption . however , dynamic interactions between bacterial factors and host response with genetic and environmental factors are considered as the primary cause for ti...	periodontal disease is a multifactorial disease having various risk factors , but a dynamic interaction between bacterial products and host response in association with genetic and environmental factors is considered as the primary cause for periodontal tissue destruction in periodontitis . this bacterial - host intera...
[ "a 61-year - old woman was referred to department of thoracic and cardiovascular surgery with thrill on the right wrist . two years earlier , she had visited the emergency department of smg - snu boramae hospital with a recently aggravated chest pain . she underwent emergency coronary angiography ( cag ) via the ri...	transradial access is a widely accepted method for percutaneous coronary diagnostic and interventional procedures , and it has dramatically reduced access site vascular complications compared to transfemoral access . arteriovenous fistula formation at the access site is an especially rare complication in transradial ac...
[ "objectivethe primary objective of this study was to evaluate the impact of the prospective team resource management methodology ( trm ) , based on the semi - p instrument , ( with and without the use of a practice enhancement associate ( pea ) ) onthe number of preventable ades in a vulnerable population aged 65 a...	background . most safety issues in primary care arise from adverse drug events . team resource management intervention was developed to identify systemic safety issues to design and implement interventions to address prioritized issues . objectives . evaluate impact of intervention on rates of events and preventable ev...
[ "usually , a slight increase in the liver function tests and mild hepatosplenomegaly occur , and sometimes , acute hepatitis develops , but hepatic abscess is a rare manifestation of that disease 1 , 2 , 3 . brucellosis is a systemic infection that may affect any organ or system of the human body .", "1).with the...	key clinical messagehepatic abscess due to brucella species is an extremely rare complication especially in acute illness . here , we report a case of hepatic microabscesses probably caused by brucella in a 33yearold woman with acute infection who was successfully treated with a combination of doxycycline and rifampici...
[ "this enables one to exert and to control forces acting on a small object in the range between 10 to 100 pn with an extraordinary high resolution of 50 fn . by incorporating additional optical systems to determine the position of a microscopic particle in 3d - space with nanometer precision , the novel experiment...	optical tweezers are microscopic tools with extraordinary precision in the determination of the position ( 2 nm ) of a colloid ( diameter : 2.0 m ) in 3d - space and in the measurement of small forces in the range between 0.1 and 100 pn ( pn=1012 n ) . experiments are reported in which single double - stranded ( ds...
[ "available published data regarding the efficacy and safety of lmwh in this clinical setting have been derived from small case series , and usually enoxaparin has been used . here in pregnant women with mechanical heart valves , the frequency of valve thrombosis increases due to pregnancy - related hypercoagulabili...	no definitive recommendation is available concerning optimal antithrombotic therapy in pregnant women with a mechanical heart valve . the purpose of the current study was to evaluate the clinical results of nadroparin treatment with respect to pregnancy outcome and maternal complications . from 1997 to 2005 , 31 pregna...
[ "the study population included patients over 18 years old who had an initial cabg or combined cabg and open chest aortic valve replacement ( avr ) , from april 1 , 1998 to october 31 , 2011 in ontario . the date of first cardiac surgery was the index date , and eligible patients were followed for 1 year with resp...	backgroundthe obesity paradox reflects an observed relationship between obesity and decreased morbidity and mortality , suggesting improved health outcomes for obese individuals . studies examining the relationship between high body mass index ( bmi ) and adverse outcomes after cardiac surgery have reported conflicti...
[ "a 7month old baby girl was brought to our hospital with a 2 months history of an ill defined mass involving entire abdomen . contrast enhanced computed tomography ( cect ) of the abdomen and pelvis revealed a small left kidney with a dilated renal pelvis that continued as a hugely dilated and tortuous ureter ( fi...	herein we present a case of a 7month old baby girl , with left single system ectopic ureter , in whom the ureter was dilated to such an extent that it presented as an abdominal mass . diagnosis was established by means of computed tomography . work up was completed with renal scan and micturating cystourethrography . ...
[ "the study was aimed at comparing the clinical and electrocardiographic findings in sickle - cell anaemia patients with raised pulmonary artery pressure with those of patients without pulmonary hypertension . pulmonary hypertension is an increasingly recognized complication of sickle - cell anaemia and a risk fac...	pulmonary hypertension is an emerging complication of sickle cell anaemia with associated increased risk of mortality . in order to evaluate the clinical and electrocardiographic findings in adult sickle - cell patients with pulmonary hypertension , a cross sectional study was conducted on sixty two sickle cell anaemia...
[ "as such , the purpose of our study was to evaluate the efficacy of the foley catheter in bladder drainage . , it would seem logical that we can reduce the incidence of cauti by addressing the problem of inadequate bladder drainage by foley catheters . one of the main complications of its use is catheter - associat...	abstractintroduction : the foley catheter has been widely assumed to be an effective means of draining the bladder . however , recent studies have brought into question its efficacy . the objective of our study is to further assess the adequacy of foley catheter for complete drainage of the bladder.materials and method...
[ "rhabdomyolysis postconvulsive seizure may limit kidney excretion of muscle breakdown products like creatine phosphokinase ( cpk ) . in this case report , levetiracetam ( lev ) is used to treat generalized and partial seizures of various etiologies .", "epilepsy etiology was due to a right frontal arteriovenous m...	a 19-year - old muscular male with a history of epilepsy presented following two convulsive events . levetiracetam ( lev ) was given as an additional therapy , resulting in a marked boost in creatine phosphokinase ( cpk ) that could not easily be explained by renal dysfunction or rhabdomyolysis alone . levetiracetam di...
[ "retinoblastoma ( rb ) is the most common intraocular malignant tumor in childhood , with an incidence of 1 in 15000 live births . although extensive epidemiologic studies have been done to study this tumor , the results have been more often misinterpreted at the expense of mutation theory which has prevailed...	retinoblastoma ( rb ) is considered to represent the prototype of cancer linked to the sequential loss or inactivation of both alleles of a so - called tumor suppressor gene , the rb1 gene . the pathogenetic mechanism behind this tumor was first hypothesized by knudson in 1971 and further confirmed by others who id...
[ "we present an adult case of acquired open bite associated with tmj - oa treated using miniscrew anchorage . if the joint collapse occurs in both tmjs , condylar resorption causes morphologic collapse of the tmjs and a subsequent decrease in ramus height , which results in progressive mandibular retrusion with ante...	this article reports the orthodontic treatment of a patient with skeletal mandibular retrusion and an anterior open bite due to temporomandibular joint osteoarthritis ( tmj - oa ) using miniscrew anchorage . a 46-year - old woman had a class ii malocclusion with a retropositioned mandible . her overjet and overbite wer...
[ "raskin coined the term thunderclap headache to refer to a similar type of headache occurring in a patient who had three severe , acute episodes of headache within 1 week . the authors concluded that unruptured intracranial aneurysms can present with thunderclap headache and that angiography is necessary in ...	thunderclap headache ( tch ) is an excruciating headache characterized by a very sudden onset . recognition and accurate diagnosis of tch are important in order to rule out the various , serious underlying brain disorders that , in a high percentage of cases , are the real cause of the headache . primary tch , which ma...
[ "this report describes a case of a one stage single - bundle revision acl reconstruction after a failed double - bundle acl reconstruction with vertical and widened tunnels . although double - bundle acl reconstruction has theoretical benefits , such as more accurate reproduction of acl anatomy , it is a more techn...	although double - bundle anterior cruciate ligament ( acl ) reconstruction has theoretical benefits such as more accurate reproduction of acl anatomy , it is technically more demanding surgery . this report describes the case of a one stage revision single - bundle acl reconstruction after primary double - bundle acl r...
[ "electronic health records ( ehrs ) are increasingly used by medical providers and offer a wide - reaching source of information on utilization of preventive services . ehr - derived measures of screening test use are subject to error due to misclassification of screening and diagnostic tests . the implications of ...	background : electronic health records ( ehrs ) are increasingly used by medical providers and offer a wide - reaching source of information on utilization of preventive services . numerous measures used for quality assessment and public reporting are estimated based on ehr data . however , sources of error and misclas...
[ "failed treatment of encrusted pyelitis in a transplanted kidney can cause graft failure or nephrectomy . to overcome urinary stasis with encrusted pyelitis in a transplanted kidney , we report surgical treatment by ileo - pelvic anastomosis without nephrectomy . corynebacterium urealyticum , a gram - positive baci...	infection stones are more likely to form after urinary diversion as the result of urinary stasis . to prevent urinary stasis due to encrusted pyelitis in a transplanted kidney , we describe an alternative a surgical treatment : ileo - pelvic anastomosis . in our patient with a transplanted kidney , the ileal conduit ha...
[ "the main drawback of sils is the loss of triangulation of surgical instruments in the operative field , which despite recent development of curved instruments and flexible endoscopes enhances technical difficulty and requires a long learning curve . laparoscopic surgery ( ls ) for both benign and neoplastic coloni...	laparoscopic colorectal resections have been shown to provide short - term advantages in terms of postoperative pain , general morbidity , recovery , and quality of life . to date , long - term results have been proved to be comparable to open surgery irrefutably only for colon cancer . recently , new trends keep arisi...
[ "this study aimed to examine the risk of vte , including both dvt and pe , in patients with gout . we hypothesized that the modest but persistent inflammation in gout may promote atherosclerosis and thrombogenesis and thus the development of cvd and vte . gout is the most common form of inflammatory arthritis and p...	abstractprevious studies indicated that gout is a risk factor of cardiovascular diseases . this study aimed to determine if patients with gout have an increased risk of deep vein thrombosis ( dvt ) or pulmonary embolism ( pe).we used the longitudinal health insurance database , a subset of the national insurance claim ...
[ "the presence of bat activity is routinely included in the radiology report at our institution . the 154 patients with bat activity constituted the study group . although serial suvmax measurements are more reproducible in individuals , a semiquantitative method of analyzing the intensity of bat depots was also dev...	objectivebrown adipose tissue ( bat ) is present in adult humans where it may be important in the prevention of obesity , although the main factors regulating its abundance are not well established . bat demonstrates seasonal variation relating to ambient temperature and photoperiod in mammals . the objective of our st...
[ "therefore , the purpose of this study was to : ( a ) describe the extent to which providers discuss , educate , and ask children and their caregivers questions about control medications and ( b ) examine how child , caregiver , and provider characteristics are associated with provider communication about control m...	background . few studies have explored how providers communicate about control medications during pediatric asthma visits . objectives . the purpose of this study was to : ( a ) describe the extent to which providers discuss , educate , and ask children and their caregivers questions about control medications and ( b )...
[ "also reduces the probability of fecal oral transmission to close contacts , such as neighbours , friends or members of the child s household . , we review the scientific evidence supporting the who - recommended antibiotics ciprofloxacin , ceftriaxone and pivmecillinam for the effective treatment of dysentery . a...	background ciprofloxacin , ceftriaxone and pivmecillinam are the antibiotics currently recommended by the world health organization ( who ) for the treatment of dysentery in children ; yet there have been no reviews of the clinical effectiveness of these antibiotics in recent years.methods we reviewed all literature re...
[ "however , a small number of hcm patients progress to lv remodeling and systolic dysfunction . such a condition is referred to as end - stage hcm , which has attracted considerable interest because of its high risk of substantial cardiovascular mortality . the reported prevalence of end - stage hcm varies from 2.4%...	background : end - stage hypertrophic cardiomyopathy ( hcm ) is complicated by substantial adverse events . however , few studies have focused on electrocardiographic features and their prognostic values in hcm . this study aimed to evaluate the clinical manifestations and prognostic value of electrocardiography in pat...
[ "thus , the aim of the present research work was to design , develope , and characterization of pentoxifylline loaded floating microballoons . it is of a wise candidate drug to be formulated in sustained release oral dosage form . rapid gastrointestinal transit could result in incomplete drug release from the drug ...	the floating microballoons have been utilized to obtain prolonged and uniform release in the stomach . the objective of the present study involves design , development , and characterization of pentoxifylline loaded floating microballoons to prolong their gastric residence time . pentoxifylline ( trisubstituted xanthin...
[ "hemimandibular hypertrophy along with its variants was first described by obwegeser and makek as a developmental deformity of unknown etiology affecting the mandible unilaterally . various studies have assumed lowered genetic control over the formation and development of bilateral structures of the face or environ...	hemimandibular hypertrophy and its variants result from unilateral excessive growth of the mandible and involve both the body and ramus of mandible . this causes facial asymmetry and in turn accompanying psychological problems . in this report we discuss use of imaging in diagnosis of these lesions and investigate the ...

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