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[ "twenty to 42% of cough do not respond to conventional medications and are referred to as refractory cough and these are often a medical challenge . cough is one of the most distressing symptoms in cancer patients with lung or mediastinal metastasis or due to complications of cancer treatment . gabapentin is known ...	vagal sensory neuropathy or vagal hypersensitivity has been implicated in the pathophysiology of chronic cough . earlier reports have shown gabapentin to be effective in sensory laryngeal neuropathy and symptom conditions that have a proven neural origin . we present a case report of a patient with chronic refractory c...
[ "recent studies have shown associations of dpp4 inhibitors efficacy with age and fasting plasma glucose levels , as well as baseline glycated hemoglobin ( hba1c ) and body mass index ( bmi ) , but clinical parameters that predict the efficacy of dpp4 inhibitors are largely unknown . dipeptidyl peptidase4 ( dpp4 ) i...	abstractthis study was initiated to identify clinical and dietary parameters that predict efficacy of dipeptidyl peptidase4 inhibitors . a total of 72 untreated japanese patients with type 2 diabetes who received dpp4 inhibitors ( sitagliptin , alogliptin or vildagliptin ) for 4 months were examined for changes of gly...
[ "for patients with non - small cell lung cancer ( nsclc ) , physicians have long been puzzled by the task of identifying candidates who may suffer major postoperative cardiopulmonary complications if they were to undergo lung resection surgery . among the few available tests , , we used statistical methods to asses...	backgroundthere is currently no reliable method to predict major postoperative cardiopulmonary complications for patients with non - small cell lung cancer ( nsclc ) . in this study , we hypothesized that exercise oxygen desaturation ( eod ) and heart rate change results in a stair - climbing test ( sct ) would predict...
[ "joint replacements are more and more frequent and routine these days thanks to , for example , the consequent aging of the general population , increased functional requirements , and the development and use of new materials and more sophisticated surgical techniques . in this context , there is a need to develop ...	surgeries for total knee replacement ( tkr ) are increasing and in this context there is a need to develop new protocols for management and use of blood transfusion therapy . autologous blood reduces the need for allogeneic blood transfusion and the aim of the present study was to verify the safety and the clinical eff...
[ "this may be spontaneous or secondary to mechanical factors like vigorous scratching or combing the hair .", "a 19-year - old female patient presented with short , rough , and unruly hair on the scalp since childhood . short curly hair on the scalp small nodules on the distal portion of hair shaft sparse hair in ...	trichonodosis is characterized by knotted hair on the distal portion of the hair shaft . this may be spontaneous or secondary to mechanical factors like vigorous scratching or combing the hair . we report a case of spontaneous trichonodosis with abnormal scalp and body hair .
[ "standard eeg techniques have been used to investigate the effect of performance level on the allocation of cortical resources during motor tasks . during the preparation of a shot , haufler et al additionally , the authors examine if resting eeg predicts brain cortical activity during exercise . in line with the n...	the neural efficiency hypothesis suggests that experts are characterized by a more efficient cortical function in cognitive tests . although this hypothesis has been extended to a variety of movement - related tasks within the last years , it is unclear whether or not neural efficiency is present in cyclists performin...
[ "the goal of the present study is to assess the perception of family medicine pcps in a university based family medicine network surrounding the barriers of preventing and treating obesity in the young child and to analyze pcps reported behaviors at well - child checks . in addition , the present study allows for a...	childhood obesity is a complex problem that warrants early intervention . general recommendations for obesity prevention and nutrition counseling exist . however , these are notably imprecise with regard to early and targeted interventions to prevent and treat obesity in pediatric populations . this study examines fami...
[ "we also evaluated its association with biochemical recurrence - free survival of patients with prostate cancer in order to analyze its potential as a biomarker in this disease . , we analyzed the methylation status of protocadherin8 in localized prostate cancer tissues using methylation - specific pcr ( msp ) . ms...	backgroundprotocadherin8 has been demonstrated to play critical roles in initiation and progression of several human cancers . it is frequently inactivated by promoter methylation in cancers and may be used as a potential biomarker . however , the methylation status of protocadherin8 and its clinical significance in pr...
[ "the local injections of phosphatidylcholine / deoxycholate solution have been gaining an increasing consensus as a non - invasive method to shrink localized adiposities . madelung 's disease is characterised by multiple disfiguring abnormal fat masses in the head , the neck , and the radix of upper limbs ; in 90% ...	madelung 's disease is characterised by multiple symmetric abnormal fat masses in the head , neck and upper limbs . surgical excision or liposuction is the only realistic available option , although palliative in nature . the serial intralipotherapy with phosphatidylcholine / deoxycholate has been proposed as a non - i...
[ "the primary purpose of this paper is to describe the clinical correlates of awareness of balance in addition to the more commonly measured awareness of function in basic and instrumental activities of daily living ( badls and iadls , resp . ) and awareness of memory . this paper provides further support for the mo...	awareness in dementia is increasingly recognized not only as multifactorial , but also as domain specific . we demonstrate differential clinical correlates for awareness of daily function , awareness of memory , and the novel exploration of awareness of balance . awareness of function was higher for participants with m...
[ "here we present three cases with definite or probable involvement of anaerobic bacteria , where hbo was used with a favourable outcome . severe skin and soft tissue infections of the head and neck are rare conditions that may emerge secondarily to oropharyngeal infections . the role of adjuvant treatment with hype...	necrotizing infections of the head and neck are rare conditions in our hospital . clinical and microbiological characteristics of three consecutive cases treated in haukeland university hospital in western norway in the year 2010 are described . two cases of lemierre 's syndrome and one case with a descending necrotizi...
[ "we report that il-6 triggers activation of pi3-k / akt signaling in 7td1 cells , and that il-6-induced pi 3-k / akt activation is essential for the optimal growth of 7td1 cells . the roles of jak / stats pathway and ras / erk pathway in the biological effects of il-6 have been extensively investigated . however , ...	backgroundrecently , growing evidence suggests the involvement of pi 3-k / akt in il-6-dependent survival and proliferative responses in several types of cells . however , whether pi 3-k / akt plays the same role in il-6-dependent growth of 7td1 mouse - mouse b cell hybridoma is not known.methodswe investigated the act...
[ "the location and characteristics of the lesion , endosonographer 's experience , needle size and type , sampling technique , sample preparation , presence of a cytopathologist for rapid on - site examination ( rose ) , and cytologist 's expertise are considered some of the important factors.1,2 issues related to n...	endoscopic ultrasound ( eus)-guided tissue acquisition is an indispensable technique for the diagnosis of many diseases of the gastrointestinal tract and adjacent structures . eus - guided fine - needle aspiration ( eus - fna ) is known for its high accuracy and low complication rate . however , the outcome of eus - fn...
[ "the titles of the final list consisting of 101 results were reviewed , 85 articles were excluded because they were not related to epidemiology of autism , and the abstracts of the remaining 16 articles were obtained . after reviewing the 16 abstracts , 6 more articles were eliminated : reviews ( n=3 ) , 2 were qua...	objective : to assess the current state of knowledge on the epidemiology of autism in arab gulf countries , and identify gaps for future research.methods:pubmed and sciencedirect databases were used to identify relevant articles published until the 3rd of april 2013 ( date of search ) . the search was conducted using t...
[ "anterior cervical discectomy and fusion ( acdf ) is a safe and standard operation for the treatment of degenerative cervical disc disease concerned with radiculopathy or myelopathy29 ) . short term clinical follow up data has been published less than 18 months after acdf with the polyetheretherketone ( peek ) cage...	objectiveto evaluate the utility of anterior cervical discectomy and fusion ( acdf ) with polyetheretherketone ( peek ) cage and autograft through long term(average 36 months ) follow-up.methodsthirty selected patients ( male:20/female:10 ) who suffered from cervical radiculopathy , myelopathy or radiculomyelopathy und...
[ "so , keeping in mind this fact , present study was conducted to analyze the effect of caries on pulpal tissue stained with quinacrine hydrochloride with the application of fluorescent microscope . developed a technique using pulpal tissue stained with quinacrine mustard , specific for y chromosome to determine sex...	aims : to determine and compare the reliability of pulp tissue in determination of sex and to analyze whether caries have any effect on fluorescent body test.materials and methods : this study was carried on 50 maxillary and mandibular teeth ( 25 male teeth and 25 female teeth ) , which were indicated for extraction . ...
[ "it is a relatively rare odontogenic lesion which exists either as a cystic or a solid variant and is characterised by varied clinical , radiographical and biological features . ccot are cysts of primordial origin and not associated with crown of any impacted tooth . is a developmental cyst of odontogenic origin an...	calcifying cystic odontogenic tumour ( ccot ) has been classified as an odontogenic tumour . ghost cell odontogenic carcinoma ( gcoc ) is the malignant counterpart of ccot . this paper aims to review the literature regarding malignant transformation of ccot.a literature search was done via the national library of medic...
[ "this retrospective study aims to get a clear view on the detection rate of adrenal incidentalomas on abdominal ct scans in our hospital , and the subsequent diagnostic procedures used after detection of this incidental finding . an adrenal incidentaloma is an adrenal mass , larger than 1 cm in diameter , detected...	objectives . the aim of this study was to investigate the detection rate of adrenal incidentalomas and subsequent workup . design . retrospective cohort study . methods . two investigators evaluated the adrenals on abdominal ct scans . abnormalities were compared to the original radiology reports and an experienced abd...
[ "we show that our implementation , with its current generative models , \n provides an improvement over the existing scoring system as measured \n by area under the curve ( auc ) on the resulting roc chart ( auc of 0.99 versus 0.78 for a complex human \n example and auc 0.85 versus 0.80 in pseudomonas ) . we descri...	the automated processing of data generated by top down proteomics would benefit from improved scoring for protein identification and characterization of highly related protein forms ( proteoforms ) . here we propose the c - score ( short for characterization score ) , a bayesian approach to the proteoform iden...
[ "a unique sliding venturi , called a phasitron , which is powered by compressed gas at 0.6 to 6 bar , generates these oscillations in the range of 80 to 650 cycles per minute.5 although several studies have addressed the physiological effects of ipv when used in copd patients , there is need for confirmation of its...	objective : chest physiotherapy enhances sputum evacuation in copd patients . it can be applied as a single technique or as a combination of techniques including intrapulmonary percussive ventilation ( ipv ) . recently developed assessment techniques may provide new insights into the effect of airway clearance techniqu...
[ "the prognosis of patients with inoperable or metastatic gists was poor until the beginning of the 21st century , when significant progress in understanding the molecular pathogenesis of gists resulted in development of a treatment that has become a model of targeted therapy in oncology . radical surgery is the tre...	on the basis of the recently published results of a clinical trial comparing 12 and 36 months of imatinib in adjuvant therapy for gastrointestinal stromal tumors ( gists ) , which demonstrated clinical benefit of longer imatinib treatment in terms of delaying recurrences and improving overall survival , both the us fo...
[ "the qol measurements are being considered increasingly important with regard to evaluating disease progression , treatment and the management of care provided to ms patients [ 2 , 3 ] . the us food and drug administration ( fda ) and the european medicines agency encourage the use of qol assessment in patients wit...	while the physical disability aspect of multiple sclerosis ( ms ) is of great importance , quality of life ( qol ) measurements are being considered increasingly important with regard to evaluating disease progression , treatment , and the management of care provided to ms patients . despite the acknowledged need to co...
[ "therefore , the aim of our present investigation was to examine whether obestatin administration exhibits any effect on the healing of chronic gastric ulcers and whether obestatin affects mucosal expression of pro - inflammatory cytokines . obestatin is a 23-amino acid peptide derived from proghrelin , a common pr...	summarybackgroundprevious studies have shown that administration of obestatin exhibits a protective effect in the pancreas , attenuating the development of acute pancreatitis . the aim of the present study was to investigate the influence of obestatin administration on the healing of chronic gastric ulcers.material/met...
[ "this report describes the design , implementation , and feasibility of the interstitial cystitis : elucidation of psychophysiologic and autonomic characteristics ( icepac ) study . typical symptoms and findings support this hypothesis ( table 1 ) , and suggest ic / bps is better conceptualized as either a chronic ...	background and purposeinterstitial cystitis / bladder pain syndrome ( ic / bps ) is relatively common and associated with severe pain , yet effective treatment remains elusive . research typically emphasized the bladder s role , but given the high presence of systemic comorbidities , the authors hypothesized a pathophy...
[ "a study developed in kindergartens and schools demonstrated that children 's voices produce considerable noise levels . over an 8-hour period , the authors recorded average noise levels of 80.1 db ( a ) near the teacher 's ear and 70.87 db ( a ) in the classroom . thus , the aim of this study was to evaluate the...	summary aim : to evaluate the sound pressure level to which preschool students are exposed . method : this was a prospective , quantitative , nonexperimental , and descriptive study . to achieve the aim of the study we used an audio dosimeter . the sound pressure level ( spl ) measurements were obtained for 2 age...
[ "the aims of this cross - sectional study were to assess the periodontal status of a group of postmenopausal women receiving hrt , and to evaluate the association between hrt and clinical measures of periodontal disease including attachment level , pocket depth and gingival bleeding . it has also been suggested tha...	summarybackgroundthe risks / benefits balance of hormone replacement therapy ( hrt ) is controversial . the aim of this study was to assess the periodontal status of a postmenopausal women group receiving hrt and to determine the effects of hrt on clinical measures of periodontal disease.material/methodsninety-one post...
[ "after all conventional methods of reversing the visual loss in our patient had failed , we resorted to a therapeutic trial of dabigatran etexilate , and the results are reported here . pars plana vitrectomy ( ppv ) is a proven and basically safe procedure with a low incidence of complications [ 1 , 2 ] . however ,...	a 46-year - old caucasian female underwent pars plana vitrectomy ( ppv ) for retinal detachment . after the procedure , the patient could only distinguish hand movements ; the condition was tentatively diagnosed as nonarteritic anterior ischemic optic neuropathy . conventional treatment with systemic corticosteroids an...
[ "the aim of this study is to estimate and compare the prevalence of smoking in 3 groups of male teachers , clergymen and university students and also their knowledge , attitude and prediction of future smoking . this is the first study in iran , which compares not only the prevalence of smoking but also evaluates k...	background : students , clergymen and teachers as role models can be very important in encouragement or prevention of cigarette smoking in young people . the aim of this study was to compare prevalence of smoking in 3 male groups of teachers , clergymen and university students . also , study their knowledge and attitud...
[ "the aim of this study is to investigate the correlation between the morning level of serum cortisol and perceptive experience of optimism in a selected group of patients with newly diagnosed cancer . results of the study investigating the influence of optimism onto the immune system have shown that optimists posse...	the aim : the aim of this study is to investigate the correlation between the morning level of serum cortisol and perceptive experience of optimism in a selected group of 60 patients with newly diagnosed cancer who were treated at mostar university clinical hospital during a one - month period.patients and methods : th...
[ "we hereby report a case of patient with primary hypothyroidism presenting with af and pericardial effusion which resolved with levothyroxine therapy . hyperthyroidism is commonly associated with atrial fibrillation ( af ) , particularly in the elderly .", "patient was treated with levothyroxine which lead to res...	a 72-year - old man presented with palpitation , dyspnea , and chest discomfort . initial investigations revealed atrial fibrillation ( af ) and pericardial effusion , further investigations unraveled primary hypothyroidism ( thyroid stimulating hormone ) of 34.7 iu / ml and total thyroxine ( t4 ) of 5.57 g / dl ) . tr...
[ "we analyzed 179 snps in 27 genes in the ber pathway in 470 recipients of allogeneic hct using alkylating agents and ionizing radiation based conditioning regimes for hematologic malignancies at university of minnesota , for association with acute and chronic gvhd . graft versus host disease ( gvhd ) remains a majo...	graft - versus - host disease ( gvhd ) is a frequent complication after hematopoietic cell transplant ( hct ) . tissue damage as a result of chemo - radiation injury is the initiating event in the pathogenesis of acute gvhd . variations in dna repair can influence the amount of tissue damage in response to alkylating a...
[ "these leaf galls are harvested and used to make kakad shringi ; a herbal medicine used to treat diarrhea in northern india . traditionally , herbs and herbal products have been considered to be nontoxic and have been used by the general public and traditional medicinal doctors worldwide to treat a range of ailment...	objectives : the goals of this research were to evaluate acute ( single - dose ) and sub - acute ( repeated - dose ) toxicity profiles of methanolic extract of pistacia integerrima j. l. stewart ex brandis ( pi ) for wistar rats and to assess the safety profile of pi by observing physiological changes , mortality , cha...
[ "this is due to the rarity of the disease in most countries where rcts have been performed and difficulty in recruiting patients , resulting in underpowered studies . a recent cochrane review comparing treatments for pemphigus found significant heterogeneity amongst the rcts with respect to the study designs , prim...	pemphigus is an autoimmune blistering disease characterized by cutaneous and mucosal blisters and erosions . though systemic corticosteroids have been the mainstay of treatment for pemphigus over the years , more recently research has focused on steroid - sparing agents . this review looks at the commonly used steroid ...
[ "participants of this study were included if they were diagnosed with a neurological condition resulting in a major physical disability ( e.g. , cerebral palsy , spina bifida , and traumatic brain injury ) . in order to achieve a homogenous sample , individuals with a medical condition that was progressive by natur...	the objective of this study was to investigate the internal consistency and the construct validity of the dutch version of the supports intensity scale ( sis - nl1.0 ; buntinx 2006 ) in individuals with physical disabilities ( n = 65 ) . to investigate the construct validity , the relationship between sis subscales a...
[ "we report a patient with purtschers - like retinopathy following childbirth who received a sub - tenon s capsule injection of triamcinolone with subsequent increase in visual acuity and decrease in retinal swelling . similar clinical findings have been reported in association with childbirth ( blodi et al 1990 ; s...	sub - tenon s injection of triamcinolone was performed in the right eye of a patient with bilateral purtschers - like retinopathy after childbirth . the response of macular edema to local triamcinolone was investigated with optical coherence tomography . five weeks following the injection , optical coherence tomography...
[ "two milk samples of 60 ml ( one at the morning milking and one at the evening milking ) were also individually collected in a plastic vial on \n the same days as the blood samples . on postpartum days 20 , \n 35 , 50 , 65 and 80 , venous blood samples were collected from the goats via jugular punctures into vacuta...	the main objectives of our study were to measure the major adipokines adiponectin , leptin and resistin in goat milk , to assess their interrelationships and to assess their relationships with the plasma and serum concentrations of total protein , cholesterol , total lipids , plasma c - reactive protein ( crp ) , mil...
[ "outcomes are time to 12-month remission and time to second treatment failure , both measured from date of first treatment failure due to inadequate seizure control or unacceptable adverse events . twelve - month remission is defined as time to 365 days of continuous seizure freedom . the methods for the sanad tria...	objectives : we assessed the likelihood of 12-month seizure remission and treatment failure after failure of a first antiepileptic drug , and identified factors influencing these outcomes.methods:sanad ( standard and new antiepileptic drug ) was a randomized controlled trial comparing monotherapy with standard and new ...
[ "we herein report a case of post - transplant vzv meningitis and myelitis that developed after the cessation of immunosuppressant therapy , which was successfully treated with the intravenous administration of foscarnet . are only rarely reported ; however , they represent severely life threatening conditions and m...	infections of the central nervous system ( cns ) with varicella zoster virus ( vzv ) is a rare occurrence after allogeneic hematopoietic stem cell transplantation . we herein report a case of vzv meningitis , radiculitis and myelitis that developed 8 months after cord blood transplantation , shortly after the cessation...
[ "therefore , we performed a series of experiments to investigate the feasibility of the endopat to evaluate acute changes in endothelial function and arterial stiffness with repeated measurements and to assess the discriminating power of the endopat in different populations . first , we investigated the variability...	endothelial dysfunction is a potential target for ( pharmaceutical ) intervention of several systemic pathological conditions . we investigated the feasibility of the endopat to evaluate acute changes in endothelial function with repeated noninvasive measurements and assessed its discriminating power in different popul...
[ "adiponectin has recently attracted much attention with particular emphasis on the role of adiponectin in the regulation of insulin sensitivity and the development of insulin resistance . adipose tissue products are reported to affect systemic metabolism ; among these are adiponectin , leptin , plasminogen activato...	background : the clustering of cardiovascular risk factors is termed the metabolic syndrome ( ms ) , which strongly predicts the risk of diabetes and cardiovascular disease ( cvd ) . adipokines may contribute to the development of obesity and insulin resistance and may be a causal link between ms , diabetes and cvd . h...
[ "in india , 23.9 lakh people were living with hiv / aids ( plha ) in 2009 and children under 15 years accounted for 3.5% of all infections . according to who / unaids estimates , 450,000 children were receiving antiretroviral therapy ( art ) and more than 2 million children still needed art in 2010 . , we report a ...	zidovudine is an important component of first - line antiretroviral treatment ( art ) regimens used to manage pediatric hiv . nail pigmentation with zidovudine is a well - documented occurrence in adults , especially dark - skinned individuals . but it has so far not been reported in children . here , we report a pedia...
[ "several chemoprotective properties of lycopene on prostate cancer have been proposed , including potent antioxidant properties , decreased lipid oxidation , inhibition of cancerous cell proliferation at the g0-g1 cell cycle transition , and protection of lipoproteins and dna [ 1 , 2 ] . the study of this relations...	lycopene has been proposed to protect against prostate cancer through various properties including decreased lipid oxidation , inhibition of cancer cell proliferation , and most notably potent antioxidant properties . epidemiologic studies on the association between lycopene and prostate cancer incidence have yielded m...
[ "various flaps used for the closure of bpf and reported in the literature are intercostal muscle flap , pericardial flap , latissimusdorsi muscle flap , serratus anterior muscle flap , rectus abdominis muscle flap and omentum . bpf is an important cause of morbidity and mortality and its management depends on vario...	a 50-year - old male patient , a known case of chronic obstructive pulmonary disease ( copd ) , presented with the features of bronchopleural fistula ( bpf ) on the right side for 1 month . the patient was a chronic smoker and did not give any history suggestive of pulmonary koch 's . the patient had sudden - onset bre...
[ "parenteral nutrition controls performed in the hospital pharmacy department are now routinely assayed for lm isolation . since the last lm outbreak in november 2006 , analysis of the 6 strains isolated in the 2006 outbreak showed different dna band patterns from those corresponding to genotype 1 ( figure 2 ) . of ...	from july 2003 through october 2004 , 42 patients became infected by strains of leuconostoc mesenteroides subsp . mesenteroides ( genotype 1 ) in different departments of juan canalejo hospital in northwest spain . during 2006 , 6 inpatients , also in different departments of the hospital , became infected ( genotypes ...
[ "the immunosuppressive receptor pd-1 and its ligand pd - l1 have been identified by dr . these findings have \n revealed the importance of the pd-1/pd - l1 pathway as an immunosuppression mechanism in a variety of tumors . based on the series of studies on pd-1/pd - l1 in tumor \n diseases , therapeutic means targe...	recently , dysfunction of antigen - specific t cells is well documented as t - cell exhaustion and has been defined by the loss of effector functions during chronic infections and cancer in human . the exhausted t cells are characterized phenotypically by the surface expression of immunoinhibitory receptors , such as...
[ "herein , we describe a woman diagnosed with repeated placenta accreta that was complicated by spontaneous rupture of the uterus . placenta accreta is a pathology characterized by abnormal and firm attachment of the placenta to the myometrium.1 the depth of penetration of the placental villi into the myometrium def...	placenta percreta is an obstetric condition in which the placenta invades through the myometrium . this is the most severe form of placenta accreta and may result in spontaneous uterine rupture , a rare complication that threatens the life of both mother and fetus . in this case report , we describe a 32-year - old wom...
[ "the online version of this article ( doi:10.1007/s40121 - 014 - 0040-z ) contains supplementary material , which is available to authorized users .", "we have suggested that a novel method for maximizing the reporting of adverse events due to drug shortages would be simple , anonymous , use standardized terminol...	introductionthe number of drug shortages in the united states has increased in recent years . while some literature exists on factors that contribute to antimicrobial shortages , the need remains to accurately gage the level of patient harm incurred as a result of realized antimicrobial shortages . furthermore , curren...
[ ", it was necessary to perform a meta - analysis to determine the association of cav1 rs3807989 polymorphism with the risk of af in the present study . however , the findings from the study of li et al . conflict with the results above ; they showed that the snp rs3807989 in cav1 gene may not be a risk factor for...	backgroundatrial fibrillation ( af ) is the most common sustained arrhythmia affected by multiple cardiovascular risk factors . it is reported that caveolin-1 gene ( cav1 ) rs3807989 polymorphism might be associated with af risk . the goal of this meta - analysis was to confirm the association between cav1 rs3807989 po...
[ "we report a case of young indian female suffering from ofd type ii ( mohr 's syndrome ) with otolaryngological manifestations . oro - facial - digital syndromes ( ofds ) are a rare heterogeneous group of development disorders in which at least nine different forms have been described . ofd ii mohr 's syndrome is t...	we present a case of oro - facial - digital syndrome type ii ( mohr 's syndrome ) which is characterized by malformations of the oral cavity , face and digits . the facial and oral features include tongue nodules , cleft or high - arched palate , missing teeth , broad nose ; cleft lip . the digital features include cli...
[ "the aim of the present study was to evaluate the change of leptin concentration in peripheral blood in patients with agp , and to explore the relationship between leptin and systemic inflammation markers . these results suggested that the systemic leptin level could be greatly influenced by the periodontal conditi...	background : increasing evidence supports an association between periodontitis and systemic diseases . leptin is involved both in the energy metabolism and inflammatory processes and is suggested to be a link between periodontal infection and systemic health . the present study aimed to evaluate the peripheral leptin c...
[ "this paper presents a report on this new system called vision that was designed , developed , and refined for breast cancer brachytherapy treatment planning . vision is based on the technique of adjuvant partial breast irradiation , uses \\documentclass[12pt]{minimal } \n\t\t\t\t \\usepackage{amsmath } \n\t\t\t\t ...	purpose brachytherapy is an option for treatment of breast cancer in some cases . this modality requires patient - specific dosimetry based on ct simulator scans . a 3d computer - assisted breast brachytherapy treatment planning system called vision was developed and tested.methods the brachytherapy treatment planning ...
[ "the histologic confirmation is necessary for the definite diagnosis and is essential in determining the treatment for patients with cardiac tumors . depending on the various clinical situations , tissue diagnosis can be made with less invasive methods including cytologic evaluation of pericardial or pleural fluids...	pathologic diagnosis of a cardiac mass is vital in determining the proper treatment modality . open heart surgery or transesophageal echocardiography guided biopsy can be feasible methods to confirm the pathology . however , the former is highly invasive and both methods require general anesthesia . the introduction of...
[ "we report a rare case of endogenous endophthalmitis caused by streptococcus equisimilis , a ggs organism . the lancefield group g beta - hemolytic streptococci ( ggs ) have been recognized as pathogens causing serious infections in humans , although ggs can have a commensal relationship when present on the skin , ...	we report a rare case of endogenous endophthalmitis caused by streptococcus equisimilis . a 74-year - old woman with endocarditis developed endogenous endophthalmitis . the patient underwent emergency mitral valvuloplasty , and intravitreal and subconjunctival injections of vancomycin and meropenem . after the surgery ...
[ "polycystic ovary syndrome ( pcos ) is the most common endocrine disorder in women of reproductive age . pcos is a medical condition , in which there is an imbalance of the female sex hormones i.e. elevated levels of testosterone , dhea - s , androstenedione , prolactin , and lh along with a normal , high or low es...	use of metformin throughout pregnancy in women with polycystic ovary syndrome ( pcos ) has shown to reduce the rates of early pregnancy loss , preterm labor , and prevention of fetal growth restriction . metformin has been shown to have encouraging effects on several metabolic aspects of polycystic ovarian syndrome , s...
[ "factorial designs , where all the factors are studied in all possible combinations , are considered the most efficient in estimating the influence of individual variables and their interactions performing minimum numbers of experiments . a computer - aided optimization technique based on 3 ( two factors and three ...	the current study deals with the development and optimization of ispaghula ( plantago ovata f. ) husk mucilage- ( ihm- ) alginate mucoadhesive beads containing glibenclamide by ionotropic gelation technique . the effects of sodium alginate ( sa ) to ihm and cross - linker ( cacl2 ) concentration on the drug encapsulati...
[ "", "this study was designed to determine the ability of plasma ptx3 levels to predict future cardiovascular events in patients with hfnef . we recently demonstrated that plasma levels of ptx3 , but not highsensitivity crp ( hscrp ) , were significantly higher in patients with hfnef than in nonhf patients . infla...	backgroundpentraxin 3 ( ptx3 ) is a novel inflammatory marker produced by various cell types including those of the vasculature and the heart . the relationship between inflammatory markers and prognosis of patients with heart failure with normal ejection fraction ( hfnef ) remains unknown . we investigated whether pla...
[ "therefore , the purpose of this study \n was to test the hypothesis that toe flexor muscle strength is related to the anatomical and \n physiological csa of intrinsic toe flexor muscles and that these morphological and \n functional variables associate with physical performance . muscle morphological characteristi...	[ purpose ] to investigate the relationships between toe flexor muscle strength with ( tfs-5-toes ) and without ( tfs-4-toes ) the contribution of the great toe , anatomical and physiological muscle cross - sectional areas ( csa ) of intrinsic toe flexor muscle and physical performance were measured . [ subjects ...
[ "cardiomyogenesis ( generation of cardiomyocytes ) had not been convincingly demonstrated in the adult mammalian heart until very recently ; the potential for myocardial regeneration was only recognized in organisms such as fish and amphibians . , controversy surrounds the putative cellular sources of postnatal car...	in recent years , several landmark studies have provided compelling evidence that cardiomyogenesis occurs in the adult mammalian heart . however , the rate of new cardiomyocyte formation is inadequate for complete restoration of the normal mass of myocardial tissue , should a significant myocardial injury occur , such ...
[ "statistical analyses were performed with stata 12.0 ( stata corp lp , college station , tx ) . the difference in the mean age of ad diagnosis between those with and without diabetes was compared with the student t test , and differences in the duration of diabetes and age at diabetes diagnosis between case and con...	objectivetype 2 diabetes in midlife or late life increases the risk of alzheimer disease ( ad ) , and type 1 diabetes has been associated with a higher risk of detrimental cognitive outcomes , although studies from older adults are lacking . we investigated whether individuals with ad were more likely to have a history...
[ "the interventions for carotid artery stenosis , vein graft and acute myocardial infarction could embolize a large amount of plaque debris , especially unstable , ulcerative , and thrombus containing lesions ( 1 ) . distal protection devices such as filterwire ex we present a case of pseudo no - reflow phenomenon a...	distal protection devices such as filterwire ex have been widely used in carotid artery stenting , however , the large amount of atherothrombotic debris entrapped in the filter could reduce or stop antegrade flow . we present a case of pseudo - no - reflow phenomenon after postdilatation of the stent in a patient with ...
[ "in this study we have evaluated the potential correlations between the histopathological features of three different skin lesions ( dysplastic nevi , thin and thick cutaneous melanomas ) and the detected number of hev blood vessels ( assessed by the expression levels of the meca-79 ) . recently , some studies repo...	purpose : tumor infiltrating lymphocytes are playing an important role in cutaneous melanoma being a strong prognostic parameter . our goal was to study the presence of high endothelial vessels in correlation with the histopathological features in different pigmented skin lesions . material and methods : our study grou...
[ "fracture of stems in primary cemented hip arthroplasty is a known complication and has been attributed to varus positioning , excessive weight of the patient , resorbtion of the femoral calcar and failure of the cement mantle . we summarize the variables affecting our patients especially regarding poor proximal su...	introduction : fracture of stems in primary total hip arthroplasty is a known complication and has been attributed to varus positioning , excessive weight of the patient , resorption of the femoral calcar and failure of the cement mantle . fractures in uncemented revision femoral stems are rare and are attributed to re...
[ "we describe our combined technique of laparoscopic and gastroscopic transgastric cystogastrostomy for pseudopancreatic cysts in children . these include open , laparoscopic , or endoscopic approaches . however , there are disadvantages and limitations with each of these techniques . the open method requires a larg...	a 15-year - old girl presented with gallstone pancreatitis . subsequently , a pseudopancreatic cyst developed that was diagnosed on computed tomographic scan . she underwent a laparoscopic and gastroscopic transgastric cystogastrostomy . in the following report , we describe our novel approach and technique for the abo...
[ "the ct reconstruction algorithm is \n overviewed , and then each of our acceleration techniques is \n described . in section 3 , numerical experiments on \n various datasets and different pcs are presented to \n evaluate the speedups with our scheme and the conventional \n implementation . in section 4 , relevant ...	expensive computational cost is a severe limitation in ct reconstruction for clinical applications that need real - time feedback . a primary example is bolus - chasing computed tomography ( ct ) angiography ( bca ) that we have been developing for the past several years . to accelerate the reconstruction process using...
[ "mechanistic data from the stoichiometric reactions \n of isolated copper amidate or imidate complexes indicate that the \n transformation of alkanes to n - alkyl products likely \n occurs by the reactions of a alkyl radicals with copper(ii ) amidate \n and imidate complexes . we sought an alternative route to the ...	we report a set of rare copper - catalyzed reactions of alkanes with simple amides , sulfonamides , and imides ( i.e. , benzamides , tosylamides , carbamates , and phthalimide ) to form the corresponding n - alkyl products . the reactions lead to functionalization at secondary c h bonds over tertiary c h bonds...
[ "the aim of this study was to investigate 1 ) whether high emotional demands or low job control were associated with suicidal ideation , and 2 ) the interactive effects of high emotional demands and low job control on suicidal ideation . therefore , we hypothesized that emotional demands and job control in the work...	we examined the relationship of high emotional demands and low job control to suicidal ideation among service and sales workers in korea . a total of 1,995 service and sales workers participated in this study . suicidal ideation and level of emotional demand and job control were assessed by self - reported questionnair...
[ "moreover , due to their affinity towards living close to river banks brings about malaria and water - borne diseases and they developed traditional healing practices to protect themselves from different diseases and traditional healing practices of those days are still preferred by the people of this community in ...	assam and arunachal pradesh have very rich tradition of herbal medicines used in the treatment of various ailments . tribal communities practice different types of traditional healing practices . enough documentation is available on the healing practices in other tribal communities except mishing community of assam and...
[ "to differentiate between the individual diagnoses of patients presenting at memory clinics with cognitive complaints and often depressive symptoms , more accurate diagnostic measures are needed . the second hypothesis is that cognitive complaints are associated with depressive symptoms and csf biomarkers are assoc...	aimsto improve early diagnosis of dementia disease , this study investigates correlates of cognitive complaints and cognitive test performance in patients with subjective ( sci ) and mild ( mci ) cognitive impairment.methodsseventy patients from a memory clinic , aged 45 - 79 , with a score of 2 ( n = 23 ) or 3 ( n = 4...
[ "the aim of the present investigation is to formulate an in situ gel using novel gum system . in situ gel solution increases the residence time and also sustain the release mechanism of the drug . the primitive ophthalmic solution , suspension , and ointment dosage forms are clearly no longer sufficient to combat t...	background / aim : the aim of the present investigation is to prepare and evaluate in situ gel - forming ophthalmic drug delivery system of moxifloxacin hydrochloride.materials and methods : sodium alginate , a novel ophthalmic gel - forming mucoadhesive polymer , which gets converted to gel in the presence of divalent...
[ "most often , it is the result of nondisjunction on chromosome 21 during maternal meiotic division . neurofibromatosis affects 1:3,000 individuals , and characterized by largely benign but often debilitating tumors that grow in the nervous system . down 's syndrome is one of the most common and easily recognized ge...	we report a patient with down 's syndrome and neurofibromatosis who presented with a keloid , sebaceous cyst and acanthosis nigricans , along with dental and ophthalmological defects . the coexistence of neurofibromatosis type 1 and down 's syndrome which are two unrelated genetic conditions is itself a rarity .
[ "modelling and analysis of the dynamics of micropolar fluids have been the field of very active research due to their application in a number of processes that occur in chemical , pharmaceutical , and food industry . the essence of the theory of micropolar fluids lies in the extension of the constitutive equations ...	an analysis study is presented to study the effects of hall current and soret effect on unsteady hydromagnetic natural convection of a micropolar fluid in a rotating frame of reference with slip - flow regime . a uniform magnetic field acts perpendicularly to the porous surface which absorbs the micropolar fluid with v...
[ "we report a case of sle - associated myopericarditis in a young male without clear evidence of viral infection based on viral markers in blood . the patient 's cardiac function dramatically improved after treatment with steroids without any additional complications .", "we concluded that the patient had sle acco...	myocardial involvement with clinical symptoms is a rare manifestation of systemic lupus erythematosus ( sle ) , despite the relatively high prevalence of myocarditis at autopsies of sle patients . in this review , we report the case of a 19-year - old male sle patient who initially presented with myopericarditis and wa...
[ "there are also reported risks such as increased incidence of hemolymphatic cancers that can be caused by microwaves generated by radars or ionizing radiation produced by electronic devices producing the microwaves ( 8) . on the other hand , there are published reports that could not show any detrimental effect in ...	backgroundradar transmitters emit high - power radiofrequency radiation by creation of a high - voltage and high - frequency alternating electrical current.methods:health effects of occupational exposure to military radar were investigated . visual reaction time was recorded with a simple blind computer - assisted - vi...
[ "the microbial population consisted of pasteurella multocida , actinomyces canis , fusobacterium and bacteroides species . re - examination 3 months after the initial incident indicated no recurrence of effusion and the cat remained free of clinical signs 2 years after presentation . conservative management was ele...	case summarya 4-year - old male neutered domestic shorthair cat was presented to the oregon state university cardiology service for suspected pericardial effusion . cardiac tamponade was documented and pericardiocentesis yielded purulent fluid with cytologic results supportive of bacterial pericarditis . the microbial ...
[ "we report a 38-year - old japanese women diagnosed with brca2 mutation that underwent prophylactic bilateral ssm with excision of the nipple to preserve the areola skin . the safety and feasibility of nipple - sparing mastectomy ( nsm ) or skin - sparing mastectomy ( ssm ) in brca mutation carriers is debatable , ...	women with brca1/2 mutations have a high risk of breast cancer and may opt for risk - reducing mastectomy ( rrm ) . we report a 38-year - old japanese woman who was diagnosed as a brca2 mutation carrier . she underwent prophylactic bilateral skin - sparing mastectomy ( ssm ) with excision of the nipple and preservation...
[ "the surveyed hmos include 15 hmos currently serving rural medicare risk enrollees , 1 hmo that recently dropped its medicare risk contract to serve rural enrollees , and 11 hmos that have commercial enrollees in 5 or more rural counties , but no rural medicare risk enrollees . the risk sample consisted of hmos s...	this article identifies factors that influence health maintenance organizations ' ( hmos ) decisions about offering a medicare risk product in rural areas ; describes hmos ' recent experiences serving rural medicare risk enrollees ; and assesses the potential impact of medicare program changes on the future willingness...
[ "randomized patients received double - blind dapagliflozin 5 or 10 mg or placebo every day ( oral administration ) with open - label pioglitazone 30 or 45 mg / day , stratified by pre - enrollment diabetes treatment group a and b. to ensure adequate representation from group a , randomization was set to recruit at ...	objectiveto examine the safety and efficacy of dapagliflozin , a sodium - glucose cotransporter-2 inhibitor , added on to pioglitazone in type 2 diabetes inadequately controlled on pioglitazone.research design and methodstreatment - naive patients or those receiving metformin , sulfonylurea , or thiazolidinedione enter...
[ "despite the large number of patients affected and the devastating consequences of medication related problems , our understanding of the impact of kidney disease on drug disposition is incomplete , particularly for those drugs eliminated primarily by non - renal pathways . obviously , clearance of drugs that depen...	the pharmacokinetics of non - renally cleared drugs in patients with chronic kidney disease is often unpredictable . some of this variability may be due to alterations in the expression and activity of extra - renal drug metabolizing enzymes and transporters , primarily localized in the liver and intestine . studies co...
[ "in this article we will use the term variable number tandem repeat ( vntr ) to encompass both microsatellites and minisatellites however not all tandem repeat domains are polymorphic in repeat copy number .", "sva elements only represent 0.13% of the genome , representing ~2700 elements , constituting the younge...	endogenous mobile genetic elements can give rise to de novo germline or somatic mutations that can have dramatic consequences for genome regulation both local and possibly more globally based on the site of integration . however if we consider them as normal genetic components of the reference genome then they are li...
[ "our goal was to evaluate the impact of bicycle riding on luts and sexual dysfunction in men with the use of amateur marathoners as a control group of physically equivalent individuals with a low level of perineal pressure or trauma . bicycling is an ideal form of aerobic , nonimpact exercise with established prote...	purposethis study was designed to determine whether men who engaged in recreational bicycle riding are more likely to be affected by lower urinary tract symptoms ( luts ) and sexual dysfunction than are man who exercised by amateur marathon running with less perineal impact.materials and methodsa total of 22 healthy ma...
[ "however , it is difficult to determine an appropriate resection line using only the laparoscopic approach . for more appropriate resection , laparoscopic and endoscopic cooperative surgery ( lecs ) on the other hand , gastric plexiform angiomyxoid myofibroblastic tumor ( pamt ) has recently emerged as a new entity...	plexiform angiomyxoid myofibroblastic tumor ( pamt ) is a recently described distinctive gastric mesenchymal entity with a peculiar plexiform pattern , bland spindle cells and a myxoid stroma rich in arborizing blood vessels . in this study , we report a new case of this rare gastric tumor resected by laparoscopic and ...
[ "myelodysplastic syndromes ( mdss ) represent a group of clonal hematological disorders characterized by progressive cytopenia reflecting defects in erythroid , myeloid and megakaryocytic maturation . we are reporting a unique case of t - pll developing in h - mds , and this is probably the first case report in the...	myelodysplastic syndrome ( mds ) represents one of the most challenging health - related problems in the elderly , characterized by dysplastic morphology in the bone marrow in association with ineffective hematopoiesis . hypoplastic mds ( h - mds ) accounts for 1217% of all patients with mds and has yet to be shown to ...
[ "567 here we describe a unique foreign body within the brain : the bristled end of an electric toothbrush , which entered the parenchyma of a patient 's right temporal lobe as a projectile through the medial orbit . intracranial foreign bodies via the transorbital route are rare.1 amongst cases of transorbital intr...	objectives intracranial penetration by foreign bodies entering via the orbit represent an unusual form of traumatic brain injury . nevertheless , much is at stake with high risk for cranial nerve and neurovascular injury . we present a case where the bristled end of a toothbrush entered the brain as a projectile via th...
[ "because \n of the therapeutic potential of inhibiting fatty acid amide \n hydrolase ( faah ) for the treatment of pain , inflammatory , or sleep disorders , there is a continuing interest in the development \n of selective inhibitors of the enzyme . herein , we report results of a systematic study of candidate inh...	a series of -ketooxazoles incorporating electrophiles at the c5 position of the pyridyl ring of 2 ( ol-135 ) and related compounds were prepared and examined as inhibitors of fatty acid amide hydrolase ( faah ) that additionally target the cytosolic port cys269 . from this series , a subset of the candidate i...
[ "to introduce a case of iridoschisis patient who underwent cataract surgery successfully without pupil device .", "a 64-year - old female who showed iridoschisis of her both eyes underwent cataract operation at her right eye without a pupillary device . the preoperative and postoperative ophthalmologic examinatio...	purposeto introduce a case of iridoschisis patient who underwent cataract surgery successfully without pupil device.methodsa 64-year - old female who showed iridoschisis of her both eyes underwent cataract operation at her right eye without a pupillary device . the preoperative and postoperative ophthalmologic examinat...
[ "this article details the design of a highly configurable , high compliance voltage , 32-electrode neurostimulator , known as neurobi , and its application in determining whether visual percepts could be elicited using a prototype suprachoroidal electrode array implanted in one patient with approximately 20 years o...	to evaluate the efficacy of a suprachoroidal retinal prosthesis , a highly configurable external neurostimulator is required . in order to meet functional and safety specifications , it was necessary to develop a custom device . a system is presented which can deliver charge - balanced , constant - current biphasic pul...
[ "urolithiasis in children remains endemic in our region afflicting children of < 1 year to 15 years of age . in developed countries , management of pediatric stone disease has shifted from the historic open surgical procedures to newer minimally invasive techniques ( mis ) , e.g. , shockwave lithotripsy ( swl ) , p...	objectivesto describe decision factors and outcome of open surgical procedures in the management of children with stone.materials and methodsbetween january 2004 and december 2008 , 3969 surgical procedures were performed in 3053 children with stone disease . procedures employed included minimally invasive techniques s...
[ "the choices of anesthesia are as varied as the operations done through the scope , and include general blocks , central neuraxial blocks , peripheral nerve blocks , and intra - articular local anesthetic techniques.1 in the last decade , bupivacaine has been the most frequently used agent for spinal and epidural a...	objectiveto determine the dose of hyperbaric bupivacaine 0.5% required for unilateral spinal anesthesia during diagnostic knee arthroscopy.patients and methodsthis prospective , randomized , clinical study was performed in 80 patients who were assigned to four groups to receive different doses of intrathecal hyperbaric...
[ "noncompaction cardiomyopathy ( nccm ) is a recently recognized rare disorder [ 1 , 2 ] . this study was designed to examine aortic stiffness in nccm patients and to compare these results to age- and gender - matched controls . it is characterized by prominent myocardial trabecularizations , and deep intertrabecula...	backgroundnoncompaction cardiomyopathy ( nccm ) is a recently recognized disorder frequently associated with systolic and diastolic heart failures . this study was designed to examine aortic stiffness in nccm patients and to compare these results to age- and gender - matched controls.methodsa total of 20 patients with ...
[ "we present a case of a patient awaiting olt , with a new finding of intrahepatic biliary ductal dilatation initially thought to be secondary to cca , but ultimately diagnosed as multiple peribiliary cysts . peribiliary cysts are often under diagnosed , however , as they are usually asymptomatic and the reported pr...	peribiliary cysts are cystic dilatations of peribiliary glands in the liver . they are present in ~50% of cirrhotic patients , but are underrecognized because they are usually asymptomatic and rarely present as obstructive jaundice . a 63-year - old male with hepatitis c cirrhosis , awaiting liver transplantation , had...
[ ", this case study describes a new concept in the management of a roc patient who has received 7 different lines of chemotherapy and has experienced recurrent disease . trabectedin + pld combination was effective as a non - platinum / non - taxane alternative to intercalate between platinum - based therapies . the ...	the goal of recurrent ovarian cancer ( roc ) treatment is no longer just palliation , but prolonging survival . this is usually through administering a new line of chemotherapy at each relapse . a novel treatment sequencing strategy to achieve this is through the intercalation of an effective non - platinum alternative...
[ ", we investigated the surgical anatomy of the alt flap in a series of eight cases , focusing on the pattern of perforators and variation in pedicle course compared with previous studies . recently , the alt flap has become a popular option for soft tissue reconstruction of the oral cavity23 . song et al.1 first re...	objectivesto gain information on anatomical variation in anterolateral thigh ( alt ) flaps in a series of clinical cases , with special focus on perforators and pedicles , for potential use in reconstruction of oral and maxillofacial soft tissue defects.materials and methodseight patients who underwent microvascular re...
[ "diabetic retinopathy is the most common complication in diabetes.1,2 it is a chronic , progressive , potentially sight - threatening disease of the retinal microvasculature that is associated with prolonged hyperglycemia and other conditions linked to diabetes mellitus such as hypertension.3 the threat to sight is...	aim of databaseto monitor the development of diabetic eye disease in denmark and to evaluate the accessibility and effectiveness of diabetic eye screening programs with focus on interregional variations.target populationthe target population includes all patients diagnosed with diabetes . denmark ( 5.5 million inhabita...
[ ", we analyzed wt1 expression in a cohort of 126 patients with aml using real - time quantitative reverse transcription polymerase chain reaction ( rq - rt - pcr ) and considered the usefulness of this marker for predicting relapse in our regions . . low expression of wt1 and high expression of it are accompanied w...	background : the wilms tumor 1 ( wt1 ) gene is originally defined as a tumor suppressor gene and a transcription factor that overexpressed in leukemic cells . it is highly expressed in more than 80% of acute myeloid leukemia ( aml ) patients , both in bone marrow ( bm ) and in peripheral blood ( pb ) , and it is used a...
[ ". these methods of assessing bioavailable and free testosterone have been used in previous studies from our research team and have determined to be reliable for the assessment of men with diabetes and vascular disease ( 17 ) . patients were seen in the morning between 8:00 and 10:00 a.m. symptoms of hypogonadism w...	objectivethere is a high prevalence of hypogonadism in men with type 2 diabetes . this will lead to an increase in assessments of hypogonadism . statins could potentially decrease testosterone levels by reducing the availability of cholesterol for androgen synthesis . we compared testosterone levels and hypogonadal sym...
[ "the aim of this work was to evaluate the use of zimomonas mobilis levans insolubilized and ferromagnetized ( fmzag-12l ) , to purify fructose / specific lectins using lectin preparations of c. mollis seeds . lectins complexed specifically to the composite were separated from other contaminant proteins by washing w...	a simple and inexpensive procedure used magnetite and levan to synthesize a composite recovered by a magnetic field . lectins from canavalia ensiformis ( con a ) and cratylia mollis ( cramoll 1 and cramoll 1 , 4 ) did bind specifically to composite . the magnetic property of derivative favored washing out contaminating...
[ "we hypothesized that the selected genetic polymorphisms ( fto rs9939609 , mc4r rs17782313 , and ppar rs1801282 ) may contribute to the occurrence and increase in metabolic and androgen disorders in aging men . we aimed to examine the relationships between the fto rs9939609 , mc4r rs17782313 , and ppar rs1801282 an...	purposemetabolic disorders , including mets , obesity , and lipid disorders , may be related to genetic factors . metabolic disorders are associated with decreased ts levels in aging men . the aim of this study was to evaluate the relationship between fto rs9939609 , mc4r rs17782313 , and ppar rs1801282 polymorphisms a...
[ "therefore , the present study was designed to evaluate the antioxidant effects of ace inhibitors with or without a sh group ( captopril and enalapril , respectively ) and to identify the involved mechanisms . there have been numerous attempts to decrease the major complications associated with cardiac surgery , an...	backgroundreactive oxygen species ( ros ) are known to be related to cardiovascular diseases . many studies have demonstrated that angiotensin - converting enzyme inhibitors have beneficial effects against ros . we investigated the antioxidant effect of captopril and enalapril in nitric oxide mediated vascular endothel...
[ "therefore , we review rehabilitation nutrition for stroke , hip fracture , hospital - associated deconditioning , and sarcopenic dysphagia , and then assess the level of research interest in rehabilitation nutrition . sarcopenic dysphagia is an important current and future public health issue , because it is commo...	malnutrition and sarcopenia often occur in rehabilitation settings . the prevalence of malnutrition and sarcopenia in older patients undergoing rehabilitation is 4967 % and 4046.5 % , respectively . malnutrition and sarcopenia are associated with poorer rehabilitation outcome and physical function . therefore , a com...
[ "nothing galvanizes the team as when the code for a foreign body ( fb ) is communicated , especially if the case is a kid where such situation is usually encountered . presentations vary , complications differ and yet , management remains the same , which is removal . presentation is acute in vegetable foreign body...	16 years old boy with childhood history of chronic respiratory symptoms requiring several admissions presented with recent worsening of symptoms . chest x - ray showed left lower lobe collapse and flexible bronchoscopy revealed stenosis of left main bronchus . foreign body was seen beyond the stenosis , which was remov...

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