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[ "we describe herein a successful case of newly diagnosed primary pcl , treated with a regimen that included bortezomib , followed by auto stem cell transplantation ( asct ) and nonmyeloablative allogeneic stem cell transplantation ( allo - sct ) . plasma cell leukemia ( pcl ) is a rare disease that represents appro...	plasma cell leukemia ( pcl ) is a rare disease that represents approximately 4% of plasma cell malignant disorders . pcl consists of two variants : primary pcl presents in patients with no previous history of multiple myeloma , while secondary pcl consists of a leukemic transformation in a previously recognized multipl...
[ "an abdominal computed tomography ( ct ) scan may reveal subcapsular enhancement of the liver in arterial phase ( 4 ) . we herein report a case of fitz hugh curtis syndrome in a male patient that was diagnosed via laparoscopy . fitz hugh curtis syndrome is an extra - pelvic manifestation of pelvic inflammatory ...	fitz hugh curtis syndrome is a condition characterized by inflammation of the liver capsule with concomitant pelvic inflammation without involvement of liver parenchyma . it is classically seen in young women who present with sharp , pleuritic right upper quadrant pain , usually but not always accompanied by symptoms...
[ "although this may seem adequate for example , the talos database contains 186 proteins subdivided into over 24,000 tripeptide fragments ( http://spin.niddk.nih.gov/nmrpipe/talos/)the sequence / conformation search space is very large , and the database coverage is unevenly distributed . as a result , rare combina...	we present simshiftdb , a new program to extract conformational data from protein chemical shifts using structural alignments . the alignments are obtained in searches of a large database containing 13,000 structures and corresponding back - calculated chemical shifts . simshiftdb makes use of chemical shift data to pr...
[ "the data reported here summarize the astigmatic changes produced with a small ( 2.2 mm ) square posterior limbal incision . sutureless clear corneal incisions are now arguably the most common incisions made to perform cataract surgery with phacoemulsification , replacing scleral tunnel and limbal incisions . vasc...	purpose . to compare the surgically induced astigmatism from clear corneal and square posterior limbal incisions at the time of cataract surgery . methods . surgically induced astigmatism was calculated for a set of eyes after cataract surgery using a temporal 2.2 mm square posterior limbal incision . results were com...
[ "the objective of this study is to compare the measurements of transverse cerebellar and anterior - posterior cisterna magna diameter obtained by 2d and 3dus using the software 3d xi in normal pregnant women between 18 and 24 weeks . the measurement of the transverse cerebellar diameter by two - dimensional ultraso...	to compare the fetal cerebellum and cisterna magna length measurements by means of two- ( 2dus ) and three - dimensional ( 3dus ) ultrasonography using the three - dimensional extended imaging ( 3d xi ) , a cross - sectional study with 69 healthy pregnant women between 18 and 24 weeks was performed . for the measuremen...
[ "ten healthy nondiabetic volunteers were recruited to serve as control subjects . finally , five patients with type 1 diabetes awaiting pancreas or islet transplant , all of whom demonstrated no c - peptide production at the time of study inclusion , served as negative control subjects . fifteen islet transplant re...	objective-cells have demonstrated altered proinsulin processing after islet transplantation . we compare -cell metabolic responses and proinsulin processing in pancreas and islet transplant recipients with respect to healthy control subjects.research design and methodswe studied 15 islet and 32 pancreas transplant reci...
[ "we have demonstrated that , melatonin is a bioprecursor of hypnotic acetyl metabolites produced by enzymatic acetylation of melatonin and 2-oxomelatonin under the control of acetyltransferases , most probably the nat enzymes . in 1994 , in our laboratory , we developed a specific and highly sensitive gas chromatog...	pharmacokinetic studies of melatonin in young and elderly human volunteers , and the measurement of hypnotic effects in chicks under alternate light - dark or permanent light conditions , show that melatonin is a bioprecursor of hypnotic acetyl metabolites produced by the enzymatic acetylation of both melatonin and 2-o...
[ "more specifically , the purposes of this study were to ( 1 ) describe sociodemographic variables , health indicators , healthcare - related frustrations , and perceptions of physician support among middle - aged and older adult women with one or more chronic conditions and ( 2 ) identify these factors ' associatio...	previous research emphasizes the importance of reducing healthcare frustrations and enhancing physician supports to help patients engage in recommended healthcare regimens . however , less is known about how these factors are associated with aging women 's knowledge about self - care behavior . this study examined the ...
[ "the purpose of this study was to examine the neural correlates of source memory in schizophrenia . while most previous studies of source memory ( in both controls and schizophrenia ) have used less ecologically valid task ( e.g. identifying the color of the stimuli during encoding ) , we utilized a paradigm involv...	source memory , the ability to identify the context in which a memory occurred , is impaired in schizophrenia and has been related to clinical symptoms such as hallucinations . the neurobiological underpinnings of this deficit are not well understood . twenty - five patients with recent onset schizophrenia ( within the...
[ "moreover , we also found that the signaling pathways used by oncogenic ras to stimulate proliferation and repress differentiation in myogenic cells are distinct and mediated independently . we report that constitutively active ras stimulates mm14 myoblast proliferation via a novel mechanism that is dependent on ex...	constitutively activated ras proteins are associated with a large number of human cancers , including those originating from skeletal muscle tissue . in this study , we show that ectopic expression of oncogenic ras stimulates proliferation of the mm14 skeletal muscle satellite cell line in the absence of exogenously ad...
[ "lipomas represent uncommon neoplasms of the oral cavity ; only 1% to 5% of cases occur at this site . based on their histopathological features of conspicuous multiple components review of the literature and clinicopathological analysis from the files of the oral pathology department , nihon university school of d...	the purpose of this study was to determine the clinicopathological and immunohistochemical features of lipoma / fibrolipoma with rare occasions as osseous and/or chondroid differentiation in the oral cavity . two cases of the tumors , who presented with a painless , relatively hard mass on the oral mucosa , were studie...
[ "leydig cell tumours are rare stromal tumours of the testis accounting for 13% of testicular neoplasms . they exhibit a peak incidence in the preadolescent as well as in the older ( > 50 years ) age groups [ 1 , 2 , 3 , 4 ] . the diagnosis of a malignant leydig cell tumour is not always easy since no definite histo...	leydig cell tumour is a benign testicular non - germ cell tumour , and malignant transformation is rare . we report a case of a 35-year - old man who came to our hospital with a painless left testicular mass measuring 1.2 1 cm . histological evaluation of the tumour showed features of a malignant leydig cell tumour bu...
[ "our study aimed to identify the role of strail in the pathophysiology of allergic rhinoconjunctivitis , and to explore whether allergen - specific subcutaneous immunotherapy treatment of allergic rhinoconjunctivitis patients altered any observed effect of strail . the prevalences of asthma , allergic rhinitis and ...	summarybackgroundallergic rhinitis is a common health problem affecting the immune system . the homeostasis of the immune system is regulated by apoptosis . in this study , serum circulating soluble trail levels of allergic rhinoconjunctivitis patients before and after allergen - specific immunotherapy were evaluated.m...
[ "calcimimetics provide an alternative approach to the traditional therapy with active vitamin d and phosphate binders for the management of secondary hyperparathyroidism ( shpt ) . type ii calcimimetics are positive allosteric modulators of the parathyroid gland calcium - sensing receptor ( car ) that increase its ...	standard therapy for secondary hyperparathyroidism ( shpt ) includes dietary calcium supplementation , active vitamin d , and phosphate binders ; however , these are often insufficient to allow patients to achieve their serum parathyroid hormone ( pth ) , calcium and calcium phosphorus product ( ca p ) targets . rece...
[ "we will mainly focus on those aggregates assembled from tau \n protein , aggregates that could be present in the neurological \n disorders known as tauopathies ( for a review see ) ( table 1 ) . recently , some good reviews have been published on protein \n aggregation and neurodegenerative disorders [ 6 , 7 ] . i...	protein aggregation takes place in many neurodegenerative disorders . however , there is a controversy about the possible toxicity of these protein aggregates . in this review , this controversy is discussed , focussing on the tau aggregation that takes place in those disorders known as tauopathies .
[ "induced abortion that can be the important complication followed by unwanted pregnancy play a significant role in the incidence of infection , fever , risk of the next premature delivery , low birth weight , and infertility [ 1 , 4 ] . therefore , conscious and accurate decision making for pregnancy and precise ca...	we aimed to find the prevalence and some factors relating with unwanted pregnancy . methods . it was a cross - sectional study on 400 randomly pregnant women , who were referring to different health centers in ahwaz city during 20...
[ "at the end of past millennium , flexible bronchoscopy was regarded as one of the most frequently performed procedures by the physicians of multiple disciplines to inspect the airway . in our institute , the fibreoptic bronchoscopies are performed by either the pulmonologists or the anaesthetist . at many places , ...	aim : the aim of the study was to compare transcricoid injection with spray as you go technique for diagnostic fibreoptic bronchoscopy , to perform the procedure without sedation and to record any complication or side effects.methods:sixty patients belonging to the age group 2070 years , undergoing diagnostic bronchosc...
[ "charcot - marie - tooth disease ( cmt ) is the most common hereditary motor and sensory neuropathy , and cmt type 1a ( cmt1a ) neuropathy , which is the most common type of cmt , is subject to a gene dosage effect.1 the primary genetic cause of cmt1a is a duplication of pmp22 resulting from the unequal crossover b...	background and purposecharcot - marie - tooth disease ( cmt ) type 1a ( cmt1a ) is the demyelinating form of cmt that is significantly associated with pmp22 duplication . some studies have found that the disease - related disabilities of these patients are correlated with their compound muscle action potentials ( cmaps...
[ "some scholars have proposed that chronic hcv infection without liver cirrhosis contributes to reduced bone mineral density , whereas other scholars have asserted the opposite . to assess the association between hcv exposure and subsequent development of osteoporosis although the role of osteoporosis as a sequence ...	abstractthe effect of hepatitis c virus ( hcv ) exposure on bone mineral density without advanced liver disease remains debated . thus , we assessed the relation between hcv exposure and the risk of osteoporosis.from 2000 to 2011 , patients aged > 20 years with hcv exposure were identified from the longitudinal health ...
[ "each disaster leaves an imprint on the affected population , a singular signature . a critical unmet need in the field of disaster mental / behavioral health is the capability to tailor mental health and psychosocial support ( mhpss ) to the unique constellation of psychological risk factors operating within eac...	trauma signature ( tsig ) analysis is an evidence - based method that examines the interrelationship between population exposure to a disaster , extreme event , or complex emergency , and the inter - related physical and psychological consequences for the purpose of providing timely , actionable guidance for effective ...
[ ", we evaluated the utility of tens for patients with spasticity due to \n cvd , who were undergoing rehabilitation , was evaluated using clinical scoring systems and \n electrophysiological assessment . spasticity is a major problem in rehabilitation programs , and it hampers patient \n progress and may trigger se...	to investigate whether transcutaneous electrical nerve stimulation ( tens ) mitigates the spasticity of hemiplegic stroke patients , as assessed by electrophysiological variables , and the effects , if any , on the clinical appearance of spasticity . [ subjects and methods ] twenty - seven subjects who had acute ...
[ "the aim of the present study is to investigate roles of thrombin , tryptase , trypsin , elastase , and agonist peptides of pars in the secretion of tnf from purified human t cells and subtypes of t cells . tnf is a major proinflammatory cytokine that is thought to be important in the pathogenesis of asthma , food ...	serine proteinases have been recognized as playing an important role in inflammation via proteinase activated receptors ( pars ) . however , little is known about the influence of serine proteinases and pars on tnf secretion from highly purified t cells . we challenged t cells from human peripheral blood with serine pr...
[ "our findings reveal that hbo2 treatment may effectively modulate the intestinal milieu in inflammatory conditions involving hif-1-mediated regulation of antioxidative gene expression . a recent study revealed increased activity of antioxidative enzymes and reduced oxidative stress in the inflamed gut mucosa follow...	reactive oxygen species ( ros ) and nitrogen species have an indispensable role in regulating cell signalling pathways , including transcriptional control via hypoxia inducible factor-1 ( hif-1 ) . hyperbaric oxygenation treatment ( hbo2 ) increases tissue oxygen content and leads to enhanced ros production . in the pr...
[ "sexuality in women is a complex issue with physiological , psychological , and cultural components . determination of sexual partner involvement , intimate relationships , and past abusive relationships is crucial in female sexual dysfunction ( fsd ) ( 1 , 2 ) . intimate sexual function is one of the best predicto...	backgroundopiate abuse in males has significant effects on their sexual functions . in contrast , sexuality in females is a multidimensional issue that can strongly be affected by several factors in their partners . however , only a limited number of studies have assessed the role of males opioid dependency in their fe...
[ "although laparoscopic appendectomy ( la ) is more expensive than is open appendectomy ( oa ) due to the costs of the disposable equipment , and can be more technically challenging in children , the overall cost of the operation has been shown to be similar to that of open appendectomy . laparoscopic surgery has ga...	background : laparoscopic surgery has reduced the length of hospital stay for common operations like cholecystectomy , gastric fundoplication , and appendectomy . we have noticed a reduction in length of hospital stay for children undergoing laparoscopic appendectomy . we , therefore , looked at our data to assess whet...
[ "a major effort in the nucleocytoplasmic transport field has been directed towards the analysis of all members of the importin family , in particular with the aim of identifying specific transport cargoes . little is known about the gross structure of the genes encoding these nuclear transport receptors , and our ...	the importin--like family of nuclear transport receptors mediates the transport of a large number of substrates between the cytoplasm and the nucleus . the family is made up of importins and exportins which shuttle between the nucleus and the cytoplasm and are regulated by the small gtpase ran .
[ "the overall objective of this research was to create an adaptive home - use robotic rehabilitation system for the upper body . this paper presents results from comparison testing between the customized exercise tasks and the standard exercise tasks , as well as preliminary testing of a pneumatically actuated proto...	robotic rehabilitation systems have been developed to treat musculoskeletal conditions , but limited availability prevents most patients from using them . the objective of this paper was to create a home - use robotic rehabilitation system . data were obtained in real time from a microsoft \documentclass[12pt]{minimal ...
[ "diabetes was related to one million deaths and mortality was higher under age of 60 years . by 2030 there will more than 79 million diabetics , making it one of the major public health challenge to the country . different studies conducted in countries like united states have observed the positive association of p...	introduction : diabetes is an important public health problem of india . studies have shown that increase in patients knowledge regarding the disease results in better compliance to treatment and decrease in complications . this study was planned to assess the knowledge about diabetes and its correlation with pharmacol...
[ "it was the german physician chemist johann joseph scherer who first demonstrated the occurrence of lactic acid in human blood under pathological conditions after death in 1843 and 1851 [ 15 , 17 ] , and carl folwarczny in 1858 who first demonstrated lactic acid in blood of a living patient . in this article lac...	lactic acid was first found and described in sour milk by karl wilhelm scheele ( 17421786 ) in 1780 . the german physician chemist johann joseph scherer ( 18411869 ) demonstrated the occurrence of lactic acid in human blood under pathological conditions in 1843 and 1851 . in this article we honour the forgotten observa...
[ ", we review recent reports investigating the skin - whitening effect of ginseng and its components and the underlying mechanisms of action , and then discuss their potential as candidates for novel skin - whitening agents . several studies have shown that ginsenosides play important roles in the pharmacological ef...	abnormal changes in skin color induce significant cosmetic problems and affect quality of life . there are two groups of abnormal change in skin color ; hyperpigmentation and hypopigmentation . hyperpigmentation , darkening skin color by excessive pigmentation , is a major concern for asian people with yellow brown sk...
[ "the aim of this retrospective investigation was to evaluate ( 1 ) possible associations between tissue kim-1 expression and tubulointerstitial ( tin ) inflammation , atrophy , and fibrosis in different chronic kidney diseases and ( 2 ) possible associations between tissue kim-1 expression and some demographic and ...	objectives . retrospective study was designed to examine the importance of tissue kidney injury molecule-1 ( kim-1 ) expression in predicting kidney function in sixty patients ( 27 males ) aged 34.15 12.23 years with different kidney diseases over three years after kidney biopsy . materials and methods . tissue kim-1 ...
[ ", nasal angiofibromas ( nas ) are the most common and nas occurring in the region other than the nose are called as extranasopharyngeal angiofibromas ( ena ) . angiofibromas are one such group of tumors arising in this region , which present as swellings . of these these range from various slow - growing benign tu...	angiofibromas are rare , benign , locally invasive vascular tumors , which represent 0.05 - 0.5% of all head and neck tumors . most frequent site of occurrence is the posterior nasopharynx , called as nasopharyngeal angiofibromas ( na ) , when these arise outside the nasopharyngeal region they are termed as extranasoph...
[ "atherosclerotic renal artery hypertension is reported in almost 7% of adults older than 65 years1 ) and is associated with cardiovascular events , and may double risk of mortality2 ) . in the 1990s , radiological angioplasty began to replace surgical revascularization . galaria et al . showed that percutaneous and...	atherosclerotic renovascular hypertension is a form of secondary hypertension due to renal artery stenosis . after the introduction of medical therapy such as with statins and angiotensin blocking agents , it has been considered a very slowly progressive disease . in the 1990s , surgical methods were compared to radiol...
[ "the results showed that mice vaccinated with rbcg186 or rbcg486 generally induced higher antigen - specific effector and memory immune responses , as well as protective efficacies compared to mice vaccinated with the parent bcg strain . however , the two rbcg strains between themselves , which expressed the chimer...	one approach for improving bcg efficacy is to utilize bcg as vehicle to develop recombinant bcg ( rbcg ) strains overexpressing mycobacterium tuberculosis ( m. tb ) antigens . also expression level of a candidate antigen should impact the final t cell responses conferred by rbcg . in this study , based on our previousl...
[ "ct now shows a hypodense body surrounded by secondary granulomatous inflammation pre - operative ( a ) and post - operative ( b ) photographs of 12-year - old boy with a history of penetrating injury by a 2 inch wooden foreign body ( c ) sustained while pond - diving a 6-year - old boy presented with a history of ...	diving into lakes and ponds is a common activity of rural children . we present two cases of penetrating orbital injuries from plant matter sustained in this manner . such injuries pose a particular challenge because wooden foreign bodies are often missed during orbital exploration , and current imaging modalities can ...
[ "the purpose of this review is to provide an evidence - based review and synthesis of the literature regarding the risks of icc when administered for the prevention of postcataract surgery endophthalmitis , thereby informing decisions regarding best practices for cataract surgery . the categories of risk to be revi...	background : endophthalmitis after cataract surgery is a rare but vision - threatening complication . intracameral cefuroxime ( icc ) has been reported to be effective at reducing the risk , but concerns regarding the risks associated with this intervention remain.methods:systematic review and synthesis of the literatu...
[ "medullary thyroid carcinoma ( mtc ) is a rare neoplasm of the calcitonin - secreting thyroid cells and accounts for 510% of all thyroid cancers . it seems , two of these ret snps ( g691s and s904s ) may modify the age at onset of mtc tumor in family members ( 5 , 15 ) but fabienne lesueur et al . have rejected thi...	abstractbackgroundmedullary thyroid carcinoma ( mtc ) occurs in both sporadic ( 75% ) and hereditary ( 25% ) forms . the missense mutations of the rearranged during transfection ( ret ) proto - oncogene in mtc development have been well demonstrated . the aim of this study was to investigate frequency of g691s / s904s ...
[ "after initial establishment and derivation of human embryonic stem cells ( hesc ; thomson et al . , 1998 ; reubinoff et al . , 2000 ) steps have been taken ; initially , hesc were grown on irradiated mouse feeders , later human fore - skin fibroblast were used ( hovatta et al . , 2003 ) , now we can use gmp compli...	human embryonic stem cells ( hesc ) and induced pluripotent stem cells ( hipsc ) are an attractive cell source for regenerative medicine . these cells can be expanded to vast numbers and can be differentiated to many desired pluripotent stem cells ( psc ) derived therapeutic cells . cell replacement bears promises , bu...
[ "to report two cases of femtosecond laser - assisted small incision deep lamellar endothelial keratoplasty ( dlek ) for patients with corneal endothelial decompensation by fuchs dystrophy and glaucoma", "irvine , ca ) with 15 khz of repetition rate , was used for a 9.5 mm diameter by 400 m thickness donor corneal...	purposeto report two cases of femtosecond laser - assisted small incision deep lamellar endothelial keratoplasty ( dlek ) for patients with corneal endothelial decompensation by fuchs dystrophy and glaucomamethodsfemtosecond laser ( intralase ; intralase corp . , irvine , ca ) with 15 khz of repetition rate , was used ...
[ "dipeptidyl peptidase-4 inhibitors ( dpp4i ) have been recently introduced in clinic as a new oral hypoglycemic agent . therefore , in this study , we investigated the effects of pacap on kidney cells and the mechanisms of how pacap decreases the expression of inflammatory cytokines . these results indicated that p...	diabetic nephropathy ( dn ) is a leading cause of end - stage kidney disease ; however , there are few treatment options . inflammation plays a crucial role in the initiation and/or progression of dn . pituitary adenylate cyclase - activating polypeptide ( pacap ) is a neuropeptide , which was originally isolated from ...
[ "dancing eye syndrome , is a serious , rare , and often chronic neurological disorder . international consensus has described three of the following four diagnostic criteria should be present to describe the typical syndrome : ( 1 ) opsoclonus , ( 2 ) myoclonus / ataxia , ( 3 ) behavioral change and/or sleep distu...	the opsoclonus - myoclonus ataxia syndrome ( omas ) also called kinsbourne syndrome or dancing eye syndrome is a rare but serious disorder characterized by opsoclonus , myoclonus , and ataxia , along with extreme irritability and behavioural changes . data on its epidemiology , clinical features , and outcome are li...
[ ". if antagonism between the two classes of drugs is really the biological basis for the aforementioned negative experience , then an optimal combination of tkis and chemotherapy should be in an intermittent , rather than a continuous schedule . this brief report presents a single - institution experience on interm...	background . intermittent application of chemotherapy and tyrosine kinase inhibitors may avoid antagonism between the two classes of drugs . this hypothesis was tested in a phase ii clinical trial . patients and methods . eligible patients were nonsmokers or light smokers , chemo - nave , with metastatic adenocarcinoma...
[ "fpv , feline parvovirus ; mev , mink enteritis virus ; cpv , canine parvovirus ; rapv , raccoon parvovirus ; rpv1 , rat parvovirus 1 ; mvmp , minute virus of mice , prototype ; hapv , hamster parvovirus ; ppv - kr , porcine parvovirus kresse ; simian bupv , simian bufavirus ; bupv1 , bufavirus 1 ; bupv2 , bufaviru...	a divergent parvovirus genome was the only eukaryotic viral sequence detected in feces of a tunisian child with unexplained diarrhea . tusavirus 1 shared 44% and 39% identity with the nonstructural protein 1 and viral protein 1 , respectively , of the closest genome , kilham rat parvovirus , indicating presence of a ne...
[ "mpi was originally derived from data collected from 1253 patients with peritonitis treated between 1963 and 1979 and was developed by discriminant analysis of 17 possible risk factors , by wacha , 8 of these were of prognostic relevance and was currently employed widely for predicting mortality from peritonitis . ...	introduction : peritonitis is one of the most common problems in general surgery practice with high mortality rate . one of the reasons for high mortality is that peritonitis affects the general condition and leads to complications causing multiple organ failure , renal failure , sepsis , and postoperative ventilatory ...
[ "maximum - likelihood phylogenetic tree of dengue virus type 1 , including isolates from key west , florida , usa , and representative isolates from 5 genotypes with global geographic distribution . during 20092010 , serum samples from patients with suspected dengue were received by the fdoh for dengue diagnostic t...	sequencing of dengue virus type 1 ( denv-1 ) strains isolated in key west / monroe county , florida , indicate endemic transmission for > 2 years of a distinct and predominant sublineage of the american african genotype . denv-1 strains isolated elsewhere in florida grouped within a separate central american lineage ....
[ "previous studies used confocal microscopy to measure epithelial thickness , but the number of points measured was limited and the measurement was time consuming . very high - frequency digital ultrasound was also used to map corneal epithelium and stromal thickness [ 4 , 5 ] . however , because ultrasound can no...	purpose . to quantify corneal epithelial thickness changes after myopic lasik by oct . methods . epithelial thickness before and after myopic lasik were measured by a fourier - domain oct system . average central ( within 1 mm diameter ) and paracentral epithelial thickness ( 5~6 mm diameter ) before and after lasik ...
[ "this is particularly the case of the health of people living in contaminated site(s ) ( cs ) which is affected by the legacy of past industrialization and current industrial activities , often in absence of environmental remediation . european community legislation addresses the concept of cs only in the context o...	sentieri project ( epidemiological study of residents in italian contaminated sites ) studied mortality in the sites of national interest for environmental remediation ( national priority contaminated sites npcss ) . sentieri described mortality of residents in npcsss , and it specifically focused on causes of death fo...
[ "the study population included 1177 patients who underwent different types of cardiac surgeries with cardiopulmonary bypass method at sina private hospital ( isfahan , iran ) , between april 2008 and september 2009 . postoperative renal risk was assessed using 2 different risk scores of a simplified predictive inde...	background : there is limited data about the influence of timing of cardiac surgery in relation to diagnostic angiography and/or the impact of the amount of contrast media used during angiography on the occurance of acute renal failure ( arf ) . therefore , in the present study the effect of the time interval between d...
[ "we investigated , through a case - control study , the relation between polymorphisms within a series of candidate genes involved in colorectal tumorigenesis and putatively in the formation and the development of colorectal adenomas such carcinogen metabolism enzymes , methylation enzymes , dna repair genes , onco...	predisposition to sporadic colorectal tumours is influenced by genes with minor phenotypic effects . a case - control study was set up on 295 patients treated for a large adenoma matched with polyp - free individuals on gender , age , and geographic origin in a 1 : 2 proportion . a second group of 302 patients treated ...
[ "our patient experienced hypovolemic shock following massive gastrointestinal hemorrhage caused by a burst - through of a pancreatic pseudocyst to the stomach . the site of origin of hemorrhage was suspected at the gastroesophageal junction , although no peptic ulcer could be discovered . gastroscopy was performed ...	acute upper gastrointestinal tract hemorrhage represents a frequent morbidity which can be localized and treated endoscopically . when endoscopic treatment alone is failing , radiological or surgical treatment may be warranted . a case history will be presented regarding a rare cause of intestinal hemorrhage with an ex...
[ "today , implant therapy is regarded as an extremely reliable approach to replace missing teeth . in the united states , emineralised bone matrix ( dbm ) is considered a transplantable tissue and therefore , is regulated primarily by the american association of tissue banks.10 treatment of dehiscence and fenestrati...	background : decalcified freeze - dried bone allograft ( dfdba ) may have the potential to enhance bone formation around dental implants . our aim in this study was the evaluation and comparison of two types of dfdba in treatment of dehiscence defects around euroteknika implants in dogs.methods:in this prospective clin...
[ "children are treated with medicines not tested for safety and efficacy and are frequently supported by the low quality of evidence . in the absence of standard prescribing information , clinicians prescribe drugs in an off - label manner . most of these studies have been conducted outside india and may not be appl...	background . in the absence of standard pediatric prescribing information , clinicians often use medicines in an off - label way . many studies have been published across the globe reporting different rates of off - label use . there is currently no study based on indian drug formulary . methods . the prospective obser...
[ "the role of the thyroid gland in pregnancy and the impact of thyroid disorders on the course of pregnancy and development of the offspring have drawn a considerable interest in the recent years , both in the medical and in the general society . about 2 and 4% american thyroid association in its recently published ...	objective : to determine the importance of screening for thyriod disorders in the first trimester of pregnancy.materials and methods : the study was conducted on 305 patients which were were randomly selected and screened on opd basis by tsh levels ( cut off level 0.10 - 2.50 miu / ml).results : in the 305 women screen...
[ "this paper demonstrates the use of surgical treatment using the laparoscopic approach in the palliative care of a patient with advanced esophageal cancer . this factor prevents curative treatment in the majority of them , thus making palliative care a more realistic option [ 1 , 3 ] . however , surgical procedures...	esophageal cancer is a devastating disease with rapidly increasing incidence in western countries . dysphagia is the most common complication , causing severe malnutrition and reduced quality of life . a 69-year - old male with persistent esophageal cancer after radiation therapy was subjected to palliative by - pass s...
[ "a provisional diagnosis of orbital dermoid was made and \n the patient was taken up for an excision biopsy . a 35-year - old female presented with a painless , slowly growing \n mass in the right inferior orbit for the past four years . the right side demonstrated a solid , non - tender , \n freely mobile mass in ...	a rare case of unilateral orbital schwannoma arising from the infraorbital nerve is presented . an excision biopsy with complete removal of the mass in the inferior orbit was performed . a definitive diagnosis was made on histopathological examination . the clinical and histological features of schwannoma are d...
[ "risperidone has been reported to be effective in management of disruptive behaviors , including hyperactivity , irritability , aggression , and temper tantrums . increased appetite , weight gain , headache , and sedation literature search revealed only four published reports of risperidone - related bleeding , inc...	there are several case reports on risperidone - related bleeding ; however , to our knowledge , there is no report about gingival bleeding associated with risperidone in the literature . we presented a case who experienced gingival bleeding when risperidone dose was increased to 0.5 mg / day , and subsided after decrea...
[ "intestinal obstruction can be a result of mechanical or functional obstruction of the intestines , thereby preventing the normal transit of the products of digestion . intestinal pseudo - obstruction ( adynamic ) , characterized by abdominal pain , nausea , vomiting , constipation , and severe abdominal distension...	baclofen is a gamma- aminobutyric acid b ( gaba b ) agonist used for the management of spasticity associated with spinal cord injury . oral baclofen might cause constipation , but intestinal pseudo - obstruction is very rare . we report a 50-year - old male with spasticity following cervical discectomy ( c3 - 4 ) on or...
[ "this sparked the interest in how excessive lipid affects -oxidation and mitochondrial biogenesis , which may have a great impact on glucose utilization and insulin resistance [ 710 ] . therefore , in this study , by establishing a mouse model , we directly explored this issue . with specific knockout of carnitine ...	objective . by specific knockout of carnitine palmitoyl transferase 1b ( cpt1b ) in skeletal muscles , we explored the effect of cpt1b deficiency on lipids and insulin sensitivity . methods . mice with specific knockout of cpt1b in skeletal muscles ( cpt1b m/ ) were used for the experiment group , with littermate c57bl...
[ "pelvic organ prolapse ( pop ) is a major healthcare problem in middle - aged and elderly women and is usually accompanied by pelvic floor dysfunction ( pfd ) . the introduction of mesh repair in vaginal prolapse surgery showed possible advantageous results in early reports . we analyzed clinical data to identify p...	background : mesh exposure after surgery continues to be a clinical challenge for urogynecological surgeons . the purpose of this study was to explore the risk factors for polypropylene ( pp ) mesh exposure after transvaginal mesh ( tvm ) surgery.methods:this study included 195 patients with advanced pelvic organ prola...
[ "5-fluorouracil ( 5-fu ) is a widely used chemotherapeutic drug and cardiac complications are not rare . however myocardial infarction , tako - tsubo - like syndrome and cardiogenic shock are also described .", ", we decided to treat this condition by the use of an extracorporeal membrane oxygenation ( ecmo ) sup...	a 50-year - old man with no previous history of cardiovascular disease or risk factors was admitted for syncope and orthopnea . importantly , he underwent recent chemotherapy with 5-fluorouracil ( 5-fu ) until 1 day before his acute presentation . in the emergency room , patient developed asystole and was successfully ...
[ "the in vivo detoxification efficacy was tested through intravenous injection of nanosponges before or after administration of a lethal dose of -toxin to icr mice , followed by monitoring the survival rate of the mice . the in vivo toxin neutralization ability of the nanosponges was tested through subcutaneous inje...	detoxification treatments such as toxin - targeted anti - virulence therapy1 , 2 offer ways to cleanse the body of virulence factors that are caused by bacterial infections , venomous injuries , and biological weaponry . because existing detoxification platforms such as antisera3 , monoclonal antibodies4 , small - mole...
[ ", we report a fatal case of enterovirus 71-induced hfmd that progressed rapidly with massive pulmonary hemorrhage and convulsion . however , to our knowledge , no cases of hfmd with sudden - onset massive pulmonary hemorrhage have been reported in korea . here pulmonary hemorrhage in enterovirus 71-infected hfmd p...	hand , foot , and mouth disease ( hfmd ) is an acute , mostly self - limiting infection . patients usually recover without any sequelae . however , a few cases are life threatening , especially those caused by enterovirus 71 ( ev71 ) . a 12-month - old boy was admitted to a primary hospital with high fever and vesicula...
[ "therefore , the present study was designed to investigate the effects of four different types of meals ( normal , high - fat , hgi , and lgi ) on fat and cho metabolism during exercise in elderly male subjects . generally , a high - fat , low - cho meal increases fat oxidation during subsequent exercise [ 46 ] , w...	the present study was designed to investigate the effects of four different meals on fat and cho metabolism during subsequent exercise in elderly males . eight healthy males ( age : 63.3 5.2 years ) reported to the physiology laboratory on four separate occasions , each of which was allocated for the performance of a ...
[ "therefore , the purpose of this study was to examine the effect of trampoline training intervention on anthropometric variables and physical fitness components of 1114-year - old male students , iran . . showed improvement in motor performance of participants with intellectual disabilities after applying trampolin...	background : physical exercises can influence some anthropometric and fitness components differently . the aim of present study was to evaluate how a relatively long - term training program in 11 - 14-year - old male iranian students affects their anthropometric and motor performance measures.methods:measurements were ...
[ "the dynamic behaviors of solitons and gaussian pulses are well described by tasakorn et al.12 by using the proposed system , the transceiver can be integrated and performed by using a single device . here , the use of the transceiver to form the transportation of microscopic volumes of matter , especially13 for mo...	a novel design of molecular buffer for molecule storage and delivery using a panda ring resonator is proposed . the optical vortices can be generated and controlled to form the trapping tools in the same way as the optical tweezers . in theory , the trapping force is formed by the combination between the gradient field...
[ "assessment of effects of different assisted reproductive techniques ( art ) like in vitro fertilization ( ivf ) and intra cytoplasmic sperm injection ( icsi ) on speech and language development needs comprehensive studies . the aim of this study is to evaluate prelinguistic behavior of 9 month old art infants of r...	objectivethe aim of this study is assessment of effects of different assisted reproductive techniques ( art ) like in vitro fertilization ( ivf ) and intra cytoplasmic sperm injection ( icsi ) on prelinguistic behavior of infants conceived by these techniques.methodsin this descriptive , cross sectional study , preling...
[ "therefore , given the importance of the cysteine proteases , this paper will focus on structural - functional relationship of falcipains , major cysteine proteases of p. falciparum . in cases of malaria , specifically , this paper will survey available information on structure and function of different domains o...	evidence indicates that cysteine proteases play essential role in malaria parasites ; therefore an obvious area of investigation is the inhibition of these enzymes to treat malaria . studies with cysteine protease inhibitors and manipulating cysteine proteases genes have suggested a role for cysteine proteases in hemog...
[ ", this information could be applied to the design of therapeutic options and prevention strategies for this devastating disease . in this review , we first summarized data on the properties of calpains and the mechanisms underlying their activation . then , we reviewed findings on the dysregulation of calpain i...	alzheimer 's disease ( ad ) is characterized by the presence of senile plaques and neurofibrillary tangles in the neocortex and hippocampus of ad patients . in addition , a marked decrease in synaptic contacts has been detected in these affected brain areas . due to its prevalence in the aging population , this disease...
[ "the research presented here provides a better understanding of how well pepfar advanced that fight and whether the allocation of a large amount of dollars for pepfar was crucial in saving lives and decreasing hiv infection rates in sub - saharan africa . the rampant level of government corruption may prevent gover...	background : hiv and aids continue to have a calamitous effect on individuals living on the continent of africa . u.s . president george w. bush implemented the president s emergency plan for aids relief ( pepfar ) with the objective of committing approximately $ 15 billion from 2004 through 2008 to assist with the red...
[ "descriptive investigation of a cluster of 5 sfts cases following exposure to an index patient who died from the disease was performed . a 77-year - old male farmer who died from sfts as for risk assessment of transmission factors , all contactors of the index patient during the period from the beginning ( 25 septe...	severe fever with thrombocytopenia syndrome bunyavirus is a newly discovered bunyavirus with high pathogenicity to human . the transmission model has been largely uncharacterized . investigation on a cluster of severe fever with thrombocytopenia syndrome cases provided evidence of person - to - person transmission thro...
[ "several studies have revealed that the mothers level of education has a positive impact on her knowledge and how she deals with child health care issues.[213 ] our experience in pediatric practice has revealed significant gaps pertaining to child health issues in the mothers knowledge . therefore , the mother 's k...	background : child care is mostly the responsibility of mothers . several studies have revealed that the mothers education has a positive impact on their knowledge and practice in child health matters.objectives:the study was undertaken to assess the level of mothers knowledge on certain aspects of child health care an...
[ "indications for covered self - expandable metallic airway stent removal include recurrent mucous plugging of the stent , excessive or recurrent granuloma formation , migration of the stent , stent infection , recurrence of stenosis , stent failure , stent fractures and accomplishment of treatment . usually , it is...	covered self expandable metallic airway stents ( sems ) have been used for benign tracheal stenosis , post intubation tracheal stenosis , tracheal burn or trauma , tracheo - broncho - malacia , and extrinsic compression of trachea . their placement is considered to be permanent , with open surgery the only way to remov...
[ "the role of meticulous monitoring and importance of anticipation of such disease for prompt diagnosis and management is emphasized . takayasu 's arteritis ( ta ) is a chronic idiopathic occlusive inflammation of aorta and its major branches predominantly affecting females in over 85% of cases . this case report de...	hemorrhagic shock is the most common reason to explain the inability to feel pulse in a trauma patient . however , clinicians should always suspect atypical causes for differential pulses in this population and takayasu 's arteritis ( ta ) is one such example . we report a case of aorto - arteritis in a patient who pre...
[ "ep , glu , and gaba in the brain samples , the present study was performed using a high efficiency hilic column for bh4 and da , a luna 3 c18 ( 3.0 mm 150 mm , i.d . , 3 m ) column for 5-ht , ne , ep , glu , and gaba with reversed - phase hplc separation and an esi - ms / ms , which could minimize the sample...	a simple and rapid liquid chromatography tandem mass spectrometry method has been developed for the determination of bh4 , da , 5-ht , ne , ep , glu , and gaba in mouse brain using epsilon - acetamidocaproic acid and isotopically labeled neurotransmitters as internal standards . proteins in the samples were precipitate...
[ "although increasing studied are focused on the roles of gper-1 in different types of cancers , the functions of gper-1 in cancers remain unclear yet . increasing attention has been paid to revealing of the functions of estrogen in physiological and pathological conditions . characteristics and functions of reprodu...	the g - protein - coupled estrogen receptor-1 ( gper-1 ) , also known as gpr30 , is a novel estrogen receptor mediating estrogen receptor signaling in multiple cell types . the progress of estrogen - related cancer is promoted by gper-1 activation through mitogen - activated protein kinases ( mapk ) , phosphoinositide ...
[ "we used male , mouse , spleenic cd4 t cells , differentiated in vitro to t helper ( th1 ) cells to produce a population of cells ( > 95% cd4 ) , of which 69% have 2n genome content , reflecting mature cell withdrawal from the cell cycle . visualization of the single cell maps suggested that despite their inherent ...	large - scale chromosome structure and spatial nuclear arrangement have been linked to control of gene expression and dna replication and repair . genomic techniques based on chromosome conformation capture assess contacts for millions of loci simultaneously , but do so by averaging chromosome conformations from millio...
[ "the external guide sequence rna for cleavage of etheo and efmn had the sequence 5-cguaaguugcggucucacca-3 , and for etheo and efmn had the sequence 5-auauucaugcggucucacca-3 ( nucleotides complementary to the target rna underlined ) . for the second pair of etheo and etheo molecules used in the multiplex experimen...	rna enzymes have been developed that undergo self - sustained replication at a constant temperature in the absence of proteins1 . these rna molecules amplify exponentially through a cross - replicative process , whereby two enzymes catalyze each other s synthesis by joining component oligonucleotides . other rna enzyme...
[ "neoadjuvant chemotherapy actually takes an important place in treatment of operable breast cancer in the hope of improving conservative surgery rate of female patients . this last decade , fnac technique is improved by the development of new cytological methods allowing standardization of fixation and assuring con...	despite the fact that cnb has been progressively replaced by fnac in the investigation of nonpalpable lesions or microcalcifications without a clinical or radiological mass lesion , fnac has yet a role in palpable lesions provided it is associated with the triple diagnosis and experienced cytologist . in these conditio...
[ "documented information about individual and household risk factors associated with malaria transmission is lacking in botswana . in order to address this paucity of information we assessed household and individual risk factors that may be contributing to malaria transmission in tubu village community in the okavan...	this study investigated potential risk factors associated with malaria transmission in tubu village , okavango subdistrict , a malaria endemic area in northern botswana . data was derived from a census questionnaire survey , participatory rural appraisal workshop , field observations , and mosquito surveys . history of...
[ "endoscopic ultrasound ( eus ) plays a pivotal role in the evaluation of patients with pancreatic cysts but eus and cross - sectional imaging alone have proven to be inaccurate in identifying the exact nature of the cysts . the prevalence of pancreatic cystic neoplasms ( pcns ) is around 2.5%.1,2 pancreatic cysts a...	incidental pancreatic cysts are being increasingly recognized recently with incremented concern about health and frequent health check - up . endoscopic ultrasound ( eus ) has emerged as the principal modality for imaging pancreas for various pancreatic diseases including pancreatic cyst . but imaging alone can not acc...
[ "brucellosis is a zoonotic disease mostly transmitted to humans through consumption of unpasteurized dairy products and can lead to a systemic disease with any organ involvement . in this report , we describe a case of brucellosis - induced avascular necrosis of the hip . the patient was treated with a combination ...	backgroundbrucellosis is a zoonotic disease mostly transmitted to humans through consumption of unpasteurized dairy products and can lead to a systemic disease with any organ involvement . in this report , we describe a case of brucellosis - induced avascular necrosis of the hip . brucellosis was diagnosed through sero...
[ "therefore , the present study was conducted on a large registry of 6,084 patients from 18 different clinics to better characterize dtm index of vascular reactivity ( vri ) in relation to patients ' phenotypes . we and other researchers have previously reported the relationships between dtm and cvd risk factors , c...	background . endothelial function is viewed as a barometer of cardiovascular health and plays a central role in vascular reactivity . several studies showed digital thermal monitoring ( dtm ) as a simple noninvasive method to measure vascular reactivity that is correlated with atherosclerosis risk factors and coronary ...
[ "however , no studies to date have evaluated the bond strength between glass - ionomers and giomers ; therefore , the aim of the present study was to evaluate the effect of three surface preparation methods on the shear bond strength of giomer to different surface treated conventional glass - ionomer . the success ...	background : an appropriate bond between glass - ionomer and the superficial resin materials is very important for the success of sandwich technique . the aim of the present in vitro study was to evaluate the effect of three surface treatments of conventional glass - ionomer on its shear bond strength to giomer.materia...
[ "the present study was designed to examine the social network size of the tehran province residents and the demographic factors affecting it in order to prepare the grounds for estimating the size of hidden populations . however , tehran , as a megacity and the capital of iran , has unique demographic , cultural , ...	abstractbackgroundnetwork scale - up is an indirect method for estimating the size of hidden , hard - to - count or high risk populations . social network size estimation is the first step in this method . the present study was conducted with the purpose of estimating the social network size of the tehran province resi...
[ "", "therefore , in the present study , the authors aimed to estimate the amount of health care utilization due to bph by surveying the records of patients who visited the designated medical institutions by the health insurance review and assessment service ( hira ) of korea . the hira monitors and analyzes reimb...	using the korean public health insurance database , we analyzed patients diagnosed as benign prostatic hyperplasia ( bph ) from 2004 to 2008 . age and year - specific amount and seasonal variation of hospital visits ( hv ) , duration of treatment ( dt ) , the total and per capita amount of insurance payment ( taip , pc...
[ "the present case is a patient with giant retroperitoneal cavernous hemangioma originating from the ilium with atypical clinical course who was referred for surgical treatment . primary retroperitoneal tumors ( prts ) of vascular origin are a diverse group of rare abdominal neoplasms , both benign and malignant an ...	retroperitoneal hemangiomas are very rare . this paper presents the case of a 71-year - old female patient with giant cavernous hemangioma of the retroperitoneum who underwent surgical treatment for abdominal pain and left lower limb edema . interventional staged treatment with percutaneous transcatheter arterial embol...
[ "in the current study , we aimed to evaluate the applicability of the 50-g gct for the detection of gmd in non - diabetic continuous ambulatory pd patients with normal fasting glucose levels . the pathogenesis of gmd in pd patients is related to factors such as weight gain and insulin resistance evoked by peritonea...	background the aim was to evaluate the clinical utility of the oral glucose tolerance screening test ( 50-g gct glucose challenge test ) for the detection of glucose metabolism disorders ( gmd ) in peritoneal dialysis ( pd ) patients with normal fasting glucose levels . methods the 50-g gct was performed in 20 pre...
[ "using proteins in aqueous solution , we demonstrated that \n the majority of protein formaldehyde adducts and cross - links were \n consistently reversed with mild heating following the removal of excess \n formaldehyde by dialysis . consequently , \n we hypothesized that the combined effects of heat and elevated ...	formaldehyde - fixed , paraffin - embedded ( ffpe ) tissue repositories represent a valuable resource for the retrospective study of disease progression and response to therapy . however , the proteomic analysis of ffpe tissues has been hampered by formaldehyde - induced protein modifications , which reduce pro...
[ "the present study was thus designed to investigate the association between polymorphisms of the vegf gene ( rs2010963 ) and the kdr gene ( rs2071559 ) and markers of carotid atherosclerosis ( such as carotid intima - media thickness ( cimt ) , the number of affected segments of carotid arteries , and the sum of pl...	background . the current study was designed to reveal possible associations between the polymorphisms of the vascular endothelial growth factor ( vegf ) gene ( rs2010963 ) and its receptor , kinase insert domain - containing receptor ( kdr ) gene polymorphism ( rs2071559 ) , and markers of carotid atherosclerosis in pa...
[ "we describe a young girl , in whom nodular hidradenoma developed at the age of 6 years . hidradenomas are benign cutaneous tumors of sweat gland origin , with the clear cell type constituting the most frequent histologic variety . usually , they are diagnosed in the elderly population , the peak incidence being th...	a 10-year - old girl presented with a swelling on her left thigh that was associated with dripping of serous fluid from the lesion . based on histological features of the excised tumor , a diagnosis of nodular hidradenoma was made . atypical features including large size of the tumor , location on the lower limb , a we...
[ "the gothenburg osteoporosis and obesity determinants ( good ) study was initiated with the aim to determine both environmental and genetic factors involved in the regulation of fat mass as previously described ( 23 ) . to be included in the good study , subjects had to be male , 18 to 20 years of age , and willing...	objectivethe amount of visceral adipose tissue is a risk factor for the metabolic syndrome . it is unclear how bmi changes during childhood and adolescence predict adult fat distribution . we hypothesized that there are critical periods during development for the prediction of adult subcutaneous and visceral fat mass b...
[ "this study is aimed at testing the efficacy of hyaluronan gel as an adjunct to caf in root coverage . however , evidence regarding the beneficial impact of these procedures on the stability of root coverage is inconclusive . hence despite sctg being the gold standard for root coverage research is always aimed at f...	background : the purpose of this study was to assess the efficacy of hyaluronic acid ( ha ) in root coverage procedures as an adjunct to coronally advanced flap ( caf ) procedure.materials and methods : this was a randomized clinical trial with split mouth design , where 10 patients with 20 sites of millers class i rec...
[ "the aim of this study is to explore the pharmacokinetic differences of the four flavonoids after oral administration of pure baicalin , radix scutellariae extract and scutellariae - paeoniae couple extract to rats and to compare the pharmacokinetic parameters of uc rats with those of normal rats . however , to the...	the aim of this study was to investigate the pharmacokinetic profiles of baicalin , wogonoside , baicalein and wogonin after oral administration of pure baicalin , radix scutellariae and scutellariae - paeoniae couple extracts were administered and the pharmacokinetics profiles were compared between normal and ulcerati...
[ "similar \n correlation of egfr with ccr was reported by khosla , et al . , although the analyzed patients were \n restricted to the population with a difference between two measurements of ccr of less than \n 25% . to clarify the actual utility of egfr in peritoneal dialysis practice weekly creatinine clearance ( ...	objective : the usefulness of estimated glomerular filtration rate may not be restricted to pre - dialysis patients , since we reported that estimated glomerular filtration rate was well correlated with measured total creatinine clearance in peritoneal dialysis patients . to clarify the clinical usefulness of est...
[ "mesenchymal stem cells ( mscs ) , also referred to as multipotent mesenchymal stromal cells , have been a focus of recent research , partially because they are an extraordinary model for investigating the biological mechanisms that allow a cellular population to generate diverse cell types and because they are a p...	mesenchymal stem cells ( mscs ) are multipotent cells capable of differentiation into mesenchymal lineages and that can be isolated from various tissues and easily cultivated in vitro . currently , mscs are of considerable interest because of the biological characteristics that confer high potential applicability in th...
[ "carpal instability is broad category consisting of various patterns of injury , with dissociative type more common .", "patient had sustained a closed distal one -third both bones fracture forearm fixed with k -wire , and volar lunate instability was found during sequential follow -up . a 13 -year -old boy prese...	introduction : carpal instability is broad category consisting of various patterns of injury , with dissociative type more common.case report : a 13 -year -old boy presented at 6 months following a fall with restriction of wrist movements . patient had sustained a closed distal one -third both bones fracture forearm fi...
[ "we sought to study the use of podocyturia to diagnose preeclampsia and differentiate it from other conditions that may have a similar presentation in a high risk pregnancy population . \n preeclampsia is a disorder affecting 5 to 10% of pregnancies and is clinically characterized by new - onset hypertension and pr...	urinary podocyte ( podocyturia ) has been studied as a diagnostic marker for preeclampsia . we sought to validate its use in preeclampsia and in differentiating it from other high risk pregnancy states . we studied an obstetric population at high risk to develop preeclampsia ( study group ) and uncomplicated pregnancie...
[ "the increasing prevalence of chronic diseases , the very different but constant environmental challenges faced by people in the developing and developed world alike , provide us with constant salutogenetic opportunities . illness is a challenge to our physical , psychological and spiritual wellbeing that has reper...	the purpose of this review is to discuss how a salutogenetic approach that takes into consideration the human being as physical , psychological and spiritual entity may provide some answers to the difficulties faced by healthcare systems . the choice of medical intervention needs to take into account the technological ...
[ "recent studies have also examined potential cross - talk between the signaling pathways that regulate autophagy and those that regulate distinct forms of regulated cell death such as apoptosis . macroautophagy ( abbreviated as autophagy ) is a genetically regulated and evolutionarily conserved pathway for the de...	autophagy represents a homeostatic cellular mechanism for the turnover of organelles and proteins , through a lysosome - dependent degradation pathway . during starvation , autophagy facilitates cell survival through the recycling of metabolic precursors . additionally , autophagy can modulate other vital processes suc...
[ "systemic symptoms are present in a third of patients at presentation and among them fever is the most common followed by night sweats and weight loss . on review of literature , we found 18 case reports with similar finding of hypotension and hypothermia associated with hl . we report the case of a patient who pre...	hypotension is an extremely rare manifestation of hodgkin lymphoma . we report the case of a patient who presented with new onset hypotension and was diagnosed with urosepsis and septic shock requiring pressor support for maintaining his blood pressure . computed tomography ( ct ) scan of abdomen showed liver lesions ,...

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