protein_name stringlengths 4 4 | structure_title stringlengths 3 322 | main_text stringlengths 0 302k |
|---|---|---|
7EXR | Crystal structure of alkaline alpha-galactosidase D383A mutant from Arabidopsis thaliana complexed with Stachyose. | research papers
154
https://doi.org/10.1107/S2059798323000037
Acta Cryst. (2023). D79, 154–167
Received 7 January 2022
Accepted 3 January 2023
Edited by G. Kurisu, Osaka University, Japan
Keywords: Arabidopsis thaliana; alkaline
-galactosidases; raffinose; RFO synthases;
transferase mechanism.
PDB references: AtAkGal... |
7EXS | Thermomicrobium roseum sarcosine oxidase mutant - S320R | Recreating the natural evolutionary trend in key
microdomains provides an effective strategy for engineering
of a thermomicrobial N-demethylase
Received for publication, November 30, 2021, and in revised form, January 22, 2022 Published, Papers in Press, February 4, 2022,
https://doi.org/10.1016/j.jbc.2022.101656
Yu Xi... |
7EXT | Cryo-EM structure of cyanobacterial phycobilisome from Synechococcus sp. PCC 7002 | ARTICLE
Structural insight into the mechanism of energy
transfer in cyanobacterial phycobilisomes
Lvqin Zheng1,5, Zhenggao Zheng2,3,5, Xiying Li2,5, Guopeng Wang1, Kun Zhang
2, Peijun Wei2,
Jindong Zhao
2,4✉& Ning Gao
1✉
Phycobilisomes (PBS) are the major light-harvesting machineries for photosynthesis in
cyanobacteria... |
7EXY | T-hairpin structure found in the RNA element involved in the piRNA biogenesis | T-hairpin structure found in the RNA element involved
in piRNA biogenesis
NAOMI TAKASE,1 MAINA OTSU,1 SHIGEKI HIRAKATA,2 HIROTSUGU ISHIZU,2,3 MIKIKO C. SIOMI,2
and GOTA KAWAI1
1Department of Life Science, Graduate School of Advanced Engineering, Chiba Institute of Technology, Chiba 275-0016, Japan
2Department of Biolog... |
7EXZ | DgpB-DgpC complex apo 2.5 angstrom | ARTICLE
C-Glycoside metabolism in the gut and in nature:
Identification, characterization, structural analyses
and distribution of C-C bond-cleaving enzymes
Takahiro Mori
1,2,3,8, Takuto Kumano
4,5,8, Haibing He1,8, Satomi Watanabe4,8, Miki Senda
6,
Toshio Moriya
6, Naruhiko Adachi
6, Sanae Hori4, Yuzu Terashita4, Masat... |
7EY0 | Local CryoEM structure of the SARS-CoV-2 S6PV2 in complex with BD-813 Fab and BD-744 Fab | LETTER TO THE EDITOR
OPEN
Structures of SARS-CoV-2 B.1.351 neutralizing antibodies
provide insights into cocktail design against concerning
variants
© The Author(s) 2021
Cell Research (2021) 31:1130–1133; https://doi.org/10.1038/s41422-021-00555-0
Dear Editor,
The spread of the SARS-CoV-2 variants, especially the globa... |
7EY4 | Local CryoEM of the SARS-CoV-2 S6PV2 in complex with BD-667 | LETTER TO THE EDITOR
OPEN
Structures of SARS-CoV-2 B.1.351 neutralizing antibodies
provide insights into cocktail design against concerning
variants
© The Author(s) 2021
Cell Research (2021) 31:1130–1133; https://doi.org/10.1038/s41422-021-00555-0
Dear Editor,
The spread of the SARS-CoV-2 variants, especially the globa... |
7EY5 | Local CryoEM structure of the SARS-CoV-2 S6PV2 in complex with BD-771 Fab and BD-821 Fab | LETTER TO THE EDITOR
OPEN
Structures of SARS-CoV-2 B.1.351 neutralizing antibodies
provide insights into cocktail design against concerning
variants
© The Author(s) 2021
Cell Research (2021) 31:1130–1133; https://doi.org/10.1038/s41422-021-00555-0
Dear Editor,
The spread of the SARS-CoV-2 variants, especially the globa... |
7EY6 | The portal protein (GP8) of bacteriophage T7 | Structural changes in bacteriophage T7 upon
receptor-induced genome ejection
Wenyuan Chena,b,1, Hao Xiaoa,c,1, Li Wangd,1, Xurong Wanga, Zhixue Tana, Zhen Hana, Xiaowu Lie, Fan Yanga,
Zhonghua Liub, Jingdong Songc,2, Hongrong Liua,2, and Lingpeng Chenga,f,2
aKey Laboratory for Matter Microstructure and Function... |
7EY7 | bacteriophage T7 tail complex | Structural changes in bacteriophage T7 upon
receptor-induced genome ejection
Wenyuan Chena,b,1, Hao Xiaoa,c,1, Li Wangd,1, Xurong Wanga, Zhixue Tana, Zhen Hana, Xiaowu Lie, Fan Yanga,
Zhonghua Liub, Jingdong Songc,2, Hongrong Liua,2, and Lingpeng Chenga,f,2
aKey Laboratory for Matter Microstructure and Function... |
7EY8 | portal | Structural changes in bacteriophage T7 upon
receptor-induced genome ejection
Wenyuan Chena,b,1, Hao Xiaoa,c,1, Li Wangd,1, Xurong Wanga, Zhixue Tana, Zhen Hana, Xiaowu Lie, Fan Yanga,
Zhonghua Liub, Jingdong Songc,2, Hongrong Liua,2, and Lingpeng Chenga,f,2
aKey Laboratory for Matter Microstructure and Function... |
7EY9 | tail proteins | Structural changes in bacteriophage T7 upon
receptor-induced genome ejection
Wenyuan Chena,b,1, Hao Xiaoa,c,1, Li Wangd,1, Xurong Wanga, Zhixue Tana, Zhen Hana, Xiaowu Lie, Fan Yanga,
Zhonghua Liub, Jingdong Songc,2, Hongrong Liua,2, and Lingpeng Chenga,f,2
aKey Laboratory for Matter Microstructure and Function... |
7EYA | Local CryoEM structure of the SARS-CoV-2 S6PV2 in complex with BD-804 Fab | LETTER TO THE EDITOR
OPEN
Structures of SARS-CoV-2 B.1.351 neutralizing antibodies
provide insights into cocktail design against concerning
variants
© The Author(s) 2021
Cell Research (2021) 31:1130–1133; https://doi.org/10.1038/s41422-021-00555-0
Dear Editor,
The spread of the SARS-CoV-2 variants, especially the globa... |
7EYB | core proteins | Structural changes in bacteriophage T7 upon
receptor-induced genome ejection
Wenyuan Chena,b,1, Hao Xiaoa,c,1, Li Wangd,1, Xurong Wanga, Zhixue Tana, Zhen Hana, Xiaowu Lie, Fan Yanga,
Zhonghua Liub, Jingdong Songc,2, Hongrong Liua,2, and Lingpeng Chenga,f,2
aKey Laboratory for Matter Microstructure and Function... |
7EYC | Crystal structure of Tau and acetylated tau peptide antigen | The Journal of Clinical Investigation
R E S E A R C H A R T I C L E
1
Introduction
Tau, a naturally soluble protein in cells of the central nervous sys-
tem, promotes microtubule assembly in healthy individuals (1, 2).
Hereditary mutations or posttranslational modifications (PTMs)
cause soluble tau molecules to... |
7EYD | Cryo-EM structure of cyanobacterial phycobilisome from Anabaena sp. PCC 7120 | ARTICLE
Structural insight into the mechanism of energy
transfer in cyanobacterial phycobilisomes
Lvqin Zheng1,5, Zhenggao Zheng2,3,5, Xiying Li2,5, Guopeng Wang1, Kun Zhang
2, Peijun Wei2,
Jindong Zhao
2,4✉& Ning Gao
1✉
Phycobilisomes (PBS) are the major light-harvesting machineries for photosynthesis in
cyanobacteria... |
7EYI | Crystal structure of ZBTB7A in complex with gamma-globin -200 sequence element with C-194A mutation | Structural basis for human ZBTB7A action at the fetal globin
promoter
Yang Yang1,2,5, Ren Ren3,5, Lana C. Ly4,5, John R. Horton3, Fudong Li2, Kate G.R. Quinlan4,
Merlin Crossley4,*, Yunyu Shi1,2,*, Xiaodong Cheng3,6,*
1Hefei National Laboratory for Physical Sciences at Microscale, School of Life Sciences, Division
o... |
7EYR | Fe(II)/(alpha)ketoglutarate-dependent dioxygenase SptF apo | ARTICLE
Molecular insights into the unusually promiscuous
and catalytically versatile Fe(II)/α-ketoglutarate-
dependent oxygenase SptF
Hui Tao1,5, Takahiro Mori
1,2,3,5✉, Heping Chen1, Shuang Lyu1, Akihito Nonoyama4, Shoukou Lee4 &
Ikuro Abe
1,2✉
Non-heme iron and α-ketoglutarate-dependent (Fe/αKG) oxygenases catalyze ... |
7EYS | Complex structure of SptF with Fe, alpha-ketoglutarate, and andiconin D | ARTICLE
Molecular insights into the unusually promiscuous
and catalytically versatile Fe(II)/α-ketoglutarate-
dependent oxygenase SptF
Hui Tao1,5, Takahiro Mori
1,2,3,5✉, Heping Chen1, Shuang Lyu1, Akihito Nonoyama4, Shoukou Lee4 &
Ikuro Abe
1,2✉
Non-heme iron and α-ketoglutarate-dependent (Fe/αKG) oxygenases catalyze ... |
7EYT | Fe(II)/(alpha)ketoglutarate-dependent dioxygenase SptF with andilesin C and NOG | ARTICLE
Molecular insights into the unusually promiscuous
and catalytically versatile Fe(II)/α-ketoglutarate-
dependent oxygenase SptF
Hui Tao1,5, Takahiro Mori
1,2,3,5✉, Heping Chen1, Shuang Lyu1, Akihito Nonoyama4, Shoukou Lee4 &
Ikuro Abe
1,2✉
Non-heme iron and α-ketoglutarate-dependent (Fe/αKG) oxygenases catalyze ... |
7EYU | Fe(II)/(alpha)ketoglutarate-dependent dioxygenase SptF-N65T mutant with andiconin D | ARTICLE
Molecular insights into the unusually promiscuous
and catalytically versatile Fe(II)/α-ketoglutarate-
dependent oxygenase SptF
Hui Tao1,5, Takahiro Mori
1,2,3,5✉, Heping Chen1, Shuang Lyu1, Akihito Nonoyama4, Shoukou Lee4 &
Ikuro Abe
1,2✉
Non-heme iron and α-ketoglutarate-dependent (Fe/αKG) oxygenases catalyze ... |
7EYW | Fe(II)/(alpha)ketoglutarate-dependent dioxygenase SptF with terretonin C | ARTICLE
Molecular insights into the unusually promiscuous
and catalytically versatile Fe(II)/α-ketoglutarate-
dependent oxygenase SptF
Hui Tao1,5, Takahiro Mori
1,2,3,5✉, Heping Chen1, Shuang Lyu1, Akihito Nonoyama4, Shoukou Lee4 &
Ikuro Abe
1,2✉
Non-heme iron and α-ketoglutarate-dependent (Fe/αKG) oxygenases catalyze ... |
7EZ0 | Apo L-21 ScaI Tetrahymena ribozyme | Cryo-EM Structures of Full-Length Tetrahymena Ribozyme at 3.1
Å Resolution
Zhaoming Su#1,2,*, Kaiming Zhang#2,5, Kalli Kappel#3, Shanshan Li2, Michael Z. Palo3,
Grigore D. Pintilie2, Ramya Rangan3, Bingnan Luo1, Yuquan Wei1, Rhiju Das3,*, Wah
Chiu2,4,*
1The State Key Laboratory of Biotherapy and Cancer Center, Depar... |
7EZ2 | Holo L-16 ScaI Tetrahymena ribozyme | Cryo-EM Structures of Full-Length Tetrahymena Ribozyme at 3.1
Å Resolution
Zhaoming Su#1,2,*, Kaiming Zhang#2,5, Kalli Kappel#3, Shanshan Li2, Michael Z. Palo3,
Grigore D. Pintilie2, Ramya Rangan3, Bingnan Luo1, Yuquan Wei1, Rhiju Das3,*, Wah
Chiu2,4,*
1The State Key Laboratory of Biotherapy and Cancer Center, Depar... |
7EZC | Adenosine A2a receptor mutant-I92N | research letters
IUCrJ (2022). 9, 333–341
https://doi.org/10.1107/S2052252522001907
333
IUCrJ
ISSN 2052-2525
BIOLOGYjMEDICINE
Received 21 September 2021
Accepted 17 February 2022
Edited by K. Moffat, University of Chicago, USA
‡ These authors contributed equally to this
work.
Keywords: constitutive active mutants;
aden... |
7EZF | Indole-2-carboxylic acid derivatives as allosteric inhibitors of fructose-1,6-bisphosphatase | Discovery of Novel Indole Derivatives as Fructose-1,6-
bisphosphatase Inhibitors and X‑ray Cocrystal Structures Analysis
Xiaoyu Wang, Rui Zhao, Wenming Ji, Jie Zhou, Quan Liu, Linxiang Zhao, Zhufang Shen, Shuainan Liu,*
and Bailing Xu*
Cite This: ACS Med. Chem. Lett. 2022, 13, 118−127
Read Online
ACCESS
Metrics & More
... |
7EZG | The structure of the human METTL6 enzyme in complex with SAH | ARTICLE
Crystal structure of human METTL6, the m3C
methyltransferase
Ran Chen1,2, Jie Zhou1, Ling Liu1, Xue-Ling Mao3, Xiaolong Zhou3 & Wei Xie
1✉
In tRNA, the epigenetic m3C modification at position 32 in the anticodon loop is highly
conserved in eukaryotes, which maintains the folding and basepairing functions of the
... |
7EZP | Indole-2-carboxylic acid derivatives as allosteric inhibitors of fructose-1,6-bisphosphatase | Discovery of Novel Indole Derivatives as Fructose-1,6-
bisphosphatase Inhibitors and X‑ray Cocrystal Structures Analysis
Xiaoyu Wang, Rui Zhao, Wenming Ji, Jie Zhou, Quan Liu, Linxiang Zhao, Zhufang Shen, Shuainan Liu,*
and Bailing Xu*
Cite This: ACS Med. Chem. Lett. 2022, 13, 118−127
Read Online
ACCESS
Metrics & More
... |
7EZR | Indole-2-carboxylic acid derivatives as allosteric inhibitors of fructose-1,6-bisphosphatase | Discovery of Novel Indole Derivatives as Fructose-1,6-
bisphosphatase Inhibitors and X‑ray Cocrystal Structures Analysis
Xiaoyu Wang, Rui Zhao, Wenming Ji, Jie Zhou, Quan Liu, Linxiang Zhao, Zhufang Shen, Shuainan Liu,*
and Bailing Xu*
Cite This: ACS Med. Chem. Lett. 2022, 13, 118−127
Read Online
ACCESS
Metrics & More
... |
7EZT | The structure and functional mechanism of nucleotide regulated acetylhexosaminidase Am2136 from Akkermansia muciniphila | RESEARCH PAPER
Nucleotide binding as an allosteric regulatory mechanism for Akkermansia
muciniphila β-N-acetylhexosaminidase Am2136
Chang-Cheng Li
a, Huan Yi
b, Yan-Mei Wang
c, Xin-Yue Tang
a, Yi-Bo Zhu
a, Ying-Jie Song
a, Ning-
Lin Zhao
a, Qin Huang
a, Xing-Yu Mou
a, Gui-Hua Luo
a, Tong-Gen Liu
a, Gang-Long Yang
d, ... |
7EZV | local CryoEM structure of the SARS-CoV-2 S6PV2 in complex with BD-812 Fab and BD-836 Fab | LETTER TO THE EDITOR
OPEN
Structures of SARS-CoV-2 B.1.351 neutralizing antibodies
provide insights into cocktail design against concerning
variants
© The Author(s) 2021
Cell Research (2021) 31:1130–1133; https://doi.org/10.1038/s41422-021-00555-0
Dear Editor,
The spread of the SARS-CoV-2 variants, especially the globa... |
7EZW | Cyclic Peptide that Interacts with the eIF4E Capped-mRNA Binding Site | 916 | RSC Chem. Biol., 2022, 3, 916–930
© 2022 The Author(s). Published by the Royal Society of Chemistry
Cite this: RSC Chem. Biol., 2022,
3, 916
Development of a novel peptide aptamer that
interacts with the eIF4E capped-mRNA binding
site using peptide epitope linker evolution (PELE)†
Yuri Frosi,‡a Simon Ng,‡a Yen-C... |
7F00 | Crystal structure of SPD_0310 | Identification and Tetramer Structure of Hemin-Binding Protein
SPD_0310 Linked to Iron Homeostasis and Virulence of
Streptococcus pneumoniae
Kun Cao,a,d Tianlong Zhang,b,c Nan Li,a Xiao-Yan Yang,a Jianping Ding,c Qing-Yu He,a
Xuesong Suna
aMOE Key Laboratory of Tumor Molecular Biology and Key Laboratory of Functional Pr... |
7F02 | Cytochrome c-type biogenesis protein CcmABCD from E. coli | Article
https://doi.org/10.1038/s41467-022-34136-5
Structures of the CcmABCD heme release
complex at multiple states
Jiao Li
1,2,4, Wan Zheng1,4, Ming Gu
1, Long Han2, Yanmei Luo1, Koukou Yu1,
Mengxin Sun1, Yuliang Zong1, Xiuxiu Ma1, Bing Liu1, Ethan P. Lowder
3,
Deanna L. Mendez3, Robert G. Kranz
3
, Kai Zhang
2
& Jia... |
7F03 | Cytochrome c-type biogenesis protein CcmABCD from E. coli in complex with ANP | Article
https://doi.org/10.1038/s41467-022-34136-5
Structures of the CcmABCD heme release
complex at multiple states
Jiao Li
1,2,4, Wan Zheng1,4, Ming Gu
1, Long Han2, Yanmei Luo1, Koukou Yu1,
Mengxin Sun1, Yuliang Zong1, Xiuxiu Ma1, Bing Liu1, Ethan P. Lowder
3,
Deanna L. Mendez3, Robert G. Kranz
3
, Kai Zhang
2
& Jia... |
7F04 | Cytochrome c-type biogenesis protein CcmABCD from E. coli in complex with Heme and ATP. | Article
https://doi.org/10.1038/s41467-022-34136-5
Structures of the CcmABCD heme release
complex at multiple states
Jiao Li
1,2,4, Wan Zheng1,4, Ming Gu
1, Long Han2, Yanmei Luo1, Koukou Yu1,
Mengxin Sun1, Yuliang Zong1, Xiuxiu Ma1, Bing Liu1, Ethan P. Lowder
3,
Deanna L. Mendez3, Robert G. Kranz
3
, Kai Zhang
2
& Jia... |
7F07 | Autonomous VH domain that interacts with eIF4E at the Capped mRNA Binding site. | 916 | RSC Chem. Biol., 2022, 3, 916–930
© 2022 The Author(s). Published by the Royal Society of Chemistry
Cite this: RSC Chem. Biol., 2022,
3, 916
Development of a novel peptide aptamer that
interacts with the eIF4E capped-mRNA binding
site using peptide epitope linker evolution (PELE)†
Yuri Frosi,‡a Simon Ng,‡a Yen-C... |
7F0D | Cryo-EM structure of Mycobacterium tuberculosis 50S ribosome subunit bound with clarithromycin | ANTIMICROBIAL AGENTS
Cryo-EM structure of Mycobacterium tuberculosis 50S ribosomal subunit bound
with clarithromycin reveals dynamic and specific interactions with macrolides
Wen Zhang
a,b†, ZhiFei Lic,d†, Yufan Sune†, Peng Cuif†, Jianhua Liangg, Qinghe Xinga, Jing Wuf, Yanhui Xua,
Wenhong Zhangf, Ying Zhangf,h, Lin Hea... |
7F0J | CryoEM structure of human Kv4.2 | 158 | Nature | Vol 599 | 4 November 2021
Article
Structural basis of gating modulation of Kv4
channel complexes
Yoshiaki Kise1,5 ✉, Go Kasuya2,5 ✉, Hiroyuki H. Okamoto1, Daichi Yamanouchi1, Kan Kobayashi1,3,
Tsukasa Kusakizako1, Tomohiro Nishizawa1,4, Koichi Nakajo2 & Osamu Nureki1 ✉
Modulation of voltage-gated... |
7F0L | STRUCTURE OF PHOTOSYNTHETIC LH1-RC SUPER-COMPLEX OF RHODOBACTER SPHAEROIDES MONOMER | ARTICLE
A previously unrecognized membrane protein in
the Rhodobacter sphaeroides LH1-RC photocomplex
Kazutoshi Tani
1,8✉, Kenji V. P. Nagashima2, Ryo Kanno3, Saki Kawamura4, Riku Kikuchi4, Malgorzata Hall3,
Long-Jiang Yu
5, Yukihiro Kimura
6, Michael T. Madigan7, Akira Mizoguchi1, Bruno M. Humbel3 &
Zheng-Yu Wang-Otom... |
7F0R | Cryo-EM structure of Pseudomonas aeruginosa SutA transcription activation complex | ARTICLE
Pseudomonas aeruginosa SutA wedges RNAP lobe
domain open to facilitate promoter DNA unwinding
Dingwei He1,2,6, Linlin You1,2,6, Xiaoxian Wu1, Jing Shi3, Aijia Wen4, Zhi Yan1, Wenhui Mu1,5, Chengli Fang
1,2,
Yu Feng
4,7✉& Yu Zhang
1,7✉
Pseudomonas aeruginosa (Pae) SutA adapts bacteria to hypoxia and nutrition-li... |
7F0S | A crystal structure of alphavirus nonstructural protein 4 (nsP4) reveals an intrinsically 1dynamic RNA-dependent RNA polymerase | 1000–1016
Nucleic Acids Research, 2022, Vol. 50, No. 2
Published online 17 January 2022
https://doi.org/10.1093/nar/gkab1302
Crystal structures of alphavirus nonstructural protein
4 (nsP4) reveal an intrinsically dynamic
RNA-dependent RNA polymerase fold
Yaw Bia Tan1,2, Laura Sandra Lello3, Xin Liu4, Yee-Song Law1,2, C... |
7F0T | Cryo-EM structure of dopamine receptor 1 and mini-Gs complex with dopamine bound | Teng et al., Sci. Adv. 8, eabo4158 (2022) 10 June 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 11
ST RUCTURAL B IOL OG Y
Structural insights into G protein activation by D1
dopamine receptor
Xiao Teng1,2†, Sijia Chen2,3†, Qing Wang2,4, Zhao Chen1,2, Xiaoying Wang2,
Niu Huang1,2, Sanduo Zheng1,2,3*
... |
7F0U | porcine epidemic diarrhea virus papain-like protease 2 C44S mutant in complex with mono ubiquitin | Structural and Biochemical Characterization of Porcine
Epidemic Diarrhea Virus Papain-Like Protease 2
Hsu-Feng Chu,a,b,c Shu-Chun Cheng,d Chiao-Yin Sun,d Chi-Yuan Chou,a,b,c† Ta-Hsien Lin,b,c,e
Wei-Yi Chend
aBiomedical Industry Ph.D. Program, National Yang Ming Chiao Tung University, Taipei, Taiwan
bDepartment of Life ... |
7F16 | Cryo-EM structure of parathyroid hormone receptor type 2 in complex with a tuberoinfundibular peptide of 39 residues and G protein | Molecular insights into differentiated ligand
recognition of the human parathyroid hormone
receptor 2
Xi Wanga,b,1, Xi Chengc,d,1, Lihua Zhaob,e,1, Yuzhe Wanga,b, Chenyu Yef, Xinyu Zoug, Antao Daia, Zhaotong Congf,
Jian Chenf, Qingtong Zhouh, Tian Xiag, Hualiang Jiangb,c,d, H. Eric Xub,e,2, Dehua Yanga,b,e,2,
and... |
7F1A | Odinarchaeota tubulin (OdinTubulin) H393D mutant, in a protofilament arrangement, bound 78% GTP/22% GDP 1 K+, 1 Mg2+ | Akıl et al., Sci. Adv. 8, eabm2225 (2022) 25 March 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 12
C EL L B IOLOGY
Structure and dynamics of Odinarchaeota
tubulin and the implications for eukaryotic
microtubule evolution
Caner Akıl1,2†, Samson Ali1,3†, Linh T. Tran1†, Jérémie Gaillard4, Wenfei Li... |
7F1B | Odinarchaeota tubulin H393D mutant, in a pseudo protofilament arrangement, after GTP hydrolysis and phosphate release | Akıl et al., Sci. Adv. 8, eabm2225 (2022) 25 March 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 12
C EL L B IOLOGY
Structure and dynamics of Odinarchaeota
tubulin and the implications for eukaryotic
microtubule evolution
Caner Akıl1,2†, Samson Ali1,3†, Linh T. Tran1†, Jérémie Gaillard4, Wenfei Li... |
7F1M | Marburg virus nucleoprotein-RNA complex | ARTICLE
Structural insight into Marburg virus
nucleoprotein–RNA complex formation
Yoko Fujita-Fujiharu
1,2,3, Yukihiko Sugita
1,2,4, Yuki Takamatsu1,9, Kazuya Houri1,2,3, Manabu Igarashi5,
Yukiko Muramoto
1,2,3, Masahiro Nakano
1,2,3, Yugo Tsunoda1,2,3, Ichiro Taniguchi
6, Stephan Becker7,8 &
Takeshi Noda
1,2,3✉
The nu... |
7F1N | Beta-Glucosidase | Frontiers in Microbiology | www.frontiersin.org
1
October 2021 | Volume 12 | Article 723678
ORIGINAL RESEARCH
published: 01 October 2021
doi: 10.3389/fmicb.2021.723678
Edited by:
Sara E Blumer-Schuette,
Oakland University, United States
Reviewed by:
Reeta Rani Singhania,
Université Clermont Auvergne,
France
Jame... |
7F1O | Cryo-EM structure of the GDP-bound dopamine receptor 1 and mini-Gs complex with Nb35 | Teng et al., Sci. Adv. 8, eabo4158 (2022) 10 June 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 11
ST RUCTURAL B IOL OG Y
Structural insights into G protein activation by D1
dopamine receptor
Xiao Teng1,2†, Sijia Chen2,3†, Qing Wang2,4, Zhao Chen1,2, Xiaoying Wang2,
Niu Huang1,2, Sanduo Zheng1,2,3*
... |
7F1Q | Cryo-EM structure of the chemokine receptor CCR5 in complex with MIP-1a and Gi | ARTICLE
Structural basis for chemokine recognition and
receptor activation of chemokine receptor CCR5
Hui Zhang1,2,3,7, Kun Chen1,2,3,7, Qiuxiang Tan1,7, Qiang Shao1,7, Shuo Han
2,7, Chenhui Zhang1,2,3, Cuiying Yi2,
Xiaojing Chu1, Ya Zhu2✉, Yechun Xu
1,3,4✉, Qiang Zhao
2,3,4,5✉& Beili Wu
1,3,4,6✉
The chemokine receptor... |
7F1R | Cryo-EM structure of the chemokine receptor CCR5 in complex with RANTES and Gi | ARTICLE
Structural basis for chemokine recognition and
receptor activation of chemokine receptor CCR5
Hui Zhang1,2,3,7, Kun Chen1,2,3,7, Qiuxiang Tan1,7, Qiang Shao1,7, Shuo Han
2,7, Chenhui Zhang1,2,3, Cuiying Yi2,
Xiaojing Chu1, Ya Zhu2✉, Yechun Xu
1,3,4✉, Qiang Zhao
2,3,4,5✉& Beili Wu
1,3,4,6✉
The chemokine receptor... |
7F1S | Cryo-EM structure of the apo chemokine receptor CCR5 in complex with Gi | ARTICLE
Structural basis for chemokine recognition and
receptor activation of chemokine receptor CCR5
Hui Zhang1,2,3,7, Kun Chen1,2,3,7, Qiuxiang Tan1,7, Qiang Shao1,7, Shuo Han
2,7, Chenhui Zhang1,2,3, Cuiying Yi2,
Xiaojing Chu1, Ya Zhu2✉, Yechun Xu
1,3,4✉, Qiang Zhao
2,3,4,5✉& Beili Wu
1,3,4,6✉
The chemokine receptor... |
7F1T | Crystal structure of the human chemokine receptor CCR5 in complex with MIP-1a | ARTICLE
Structural basis for chemokine recognition and
receptor activation of chemokine receptor CCR5
Hui Zhang1,2,3,7, Kun Chen1,2,3,7, Qiuxiang Tan1,7, Qiang Shao1,7, Shuo Han
2,7, Chenhui Zhang1,2,3, Cuiying Yi2,
Xiaojing Chu1, Ya Zhu2✉, Yechun Xu
1,3,4✉, Qiang Zhao
2,3,4,5✉& Beili Wu
1,3,4,6✉
The chemokine receptor... |
7F1W | X-ray crystal structure of visual arrestin complexed with inositol hexaphosphate | Structural evidence for visual arrestin priming via complexation
of phosphoinositols
Christopher L. Sander1,2, Jennings Luu1,2, Kyumhyuk Kim3, David Furkert4, Kiyoung
Jang5, Joerg Reichenwallner3, MinSoung Kang5,6, Ho-Jun Lee2,12, Bryan T. Eger3,
Hui-Woog Choe7, Dorothea Fiedler4, Oliver P. Ernst3,9, Yong Ju Kim5,8,... |
7F1X | X-ray crystal structure of visual arrestin complexed with inositol 1,4,5-triphosphate | Structural evidence for visual arrestin priming via complexation
of phosphoinositols
Christopher L. Sander1,2, Jennings Luu1,2, Kyumhyuk Kim3, David Furkert4, Kiyoung
Jang5, Joerg Reichenwallner3, MinSoung Kang5,6, Ho-Jun Lee2,12, Bryan T. Eger3,
Hui-Woog Choe7, Dorothea Fiedler4, Oliver P. Ernst3,9, Yong Ju Kim5,8,... |
7F1Z | Cryo-EM structure of the GDP-bound dopamine receptor 1 and mini-Gs complex without Nb35 | Teng et al., Sci. Adv. 8, eabo4158 (2022) 10 June 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 11
ST RUCTURAL B IOL OG Y
Structural insights into G protein activation by D1
dopamine receptor
Xiao Teng1,2†, Sijia Chen2,3†, Qing Wang2,4, Zhao Chen1,2, Xiaoying Wang2,
Niu Huang1,2, Sanduo Zheng1,2,3*
... |
7F23 | Cryo-EM structure of the GTP-bound dopamine receptor 1 and mini-Gs complex with Nb35 | Teng et al., Sci. Adv. 8, eabo4158 (2022) 10 June 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 11
ST RUCTURAL B IOL OG Y
Structural insights into G protein activation by D1
dopamine receptor
Xiao Teng1,2†, Sijia Chen2,3†, Qing Wang2,4, Zhao Chen1,2, Xiaoying Wang2,
Niu Huang1,2, Sanduo Zheng1,2,3*
... |
7F24 | Cryo-EM structure of the GTP-bound dopamine receptor 1 and mini-Gs complex without Nb35 | Teng et al., Sci. Adv. 8, eabo4158 (2022) 10 June 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 11
ST RUCTURAL B IOL OG Y
Structural insights into G protein activation by D1
dopamine receptor
Xiao Teng1,2†, Sijia Chen2,3†, Qing Wang2,4, Zhao Chen1,2, Xiaoying Wang2,
Niu Huang1,2, Sanduo Zheng1,2,3*
... |
7F25 | Crystal structure of SSB from Salmonella enterica serovar Typhimurium LT2. |
Citation: Lin, E.-S.; Huang, Y.-H.;
Luo, R.-H.; Basharat, Z.; Huang, C.-Y.
Crystal Structure of an SSB Protein
from Salmonella enterica and Its
Inhibition by Flavanonol Taxifolin.
Int. J. Mol. Sci. 2022, 23, 4399.
https://doi.org/10.3390/
ijms23084399
Academic Editor: Adel Nefzi
Received: 29 March 202... |
7F26 | Crystal structure of lysozyme | methods communications
Acta Cryst. (2021). F77, 319–327
https://doi.org/10.1107/S2053230X21008104
319
Received 11 June 2021
Accepted 6 August 2021
Edited by J. Newman, Bio21 Collaborative
Crystallisation Centre, Australia
Keywords: in situ diffraction; automatic
sampling; automatic sample loading; crystal
screening; cr... |
7F27 | Crystal structure of polyketide ketosynthase | 1
Vol.:(0123456789)
Scientific Reports | (2021) 11:16340
| https://doi.org/10.1038/s41598-021-95890-y
www.nature.com/scientificreports
Structural basis
of the complementary activity
of two ketosynthases in aryl
polyene biosynthesis
Woo Cheol Lee1, Sungjae Choi1, Ahjin Jang1, Jiwon Yeon1, Eunha Hwang2 & Yang... |
7F28 | Crystal structure of a bacterial ketosynthase | 1
Vol.:(0123456789)
Scientific Reports | (2021) 11:16340
| https://doi.org/10.1038/s41598-021-95890-y
www.nature.com/scientificreports
Structural basis
of the complementary activity
of two ketosynthases in aryl
polyene biosynthesis
Woo Cheol Lee1, Sungjae Choi1, Ahjin Jang1, Jiwon Yeon1, Eunha Hwang2 & Yang... |
7F2B | Crystal structure of SARS-CoV-2 nucleocapsid protein C-terminal RNA binding domain at 2.0A resolution | Crystal structures of the SARS-CoV-2 nucleocapsid
protein C-terminal domain and development of
nucleocapsid-targeting nanobodies
Zhenghu Jia1,2,3, Chen Liu2, Yuewen Chen2, Heng Jiang2, Zijing Wang2, Jialu Yao2, Jie Yang3,
Jiaxing Zhu3, Boqing Zhang3 and Zhiguang Yuchi2
1 The First Affiliated Hospital, Biomedical Transla... |
7F2D | Arabidopsis thaliana protease-associated domain of vacuolar-sorting receptor 1 in complex with cruciferin 1 C-terminal pentapeptide RVAAA (pH9) | Structural insights into how vacuolar sorting
receptors recognize the sorting determinants
of seed storage proteins
Hsi-En Tsaoa,1
, Shu Nga Luia,1
, Anthony Hiu-Fung Loa,1
, Shuai Chena
, Hiu Yan Wonga, Chi-Kin Wonga,
Liwen Jiangb,c,d,e, and Kam-Bo Wonga,2
aCentre for Protein Science and Crystallography, School of Lif... |
7F2E | SARS-CoV-2 nucleocapsid protein C-terminal domain (dodecamer) | Crystal structures of the SARS-CoV-2 nucleocapsid
protein C-terminal domain and development of
nucleocapsid-targeting nanobodies
Zhenghu Jia1,2,3, Chen Liu2, Yuewen Chen2, Heng Jiang2, Zijing Wang2, Jialu Yao2, Jie Yang3,
Jiaxing Zhu3, Boqing Zhang3 and Zhiguang Yuchi2
1 The First Affiliated Hospital, Biomedical Transla... |
7F2I | Arabidopsis thaliana protease-associated domain of vacuolar-sorting receptor 1 in complex with cruciferin 1 C-terminal pentapeptide RVAAA (pH6.5) | Structural insights into how vacuolar sorting
receptors recognize the sorting determinants
of seed storage proteins
Hsi-En Tsaoa,1
, Shu Nga Luia,1
, Anthony Hiu-Fung Loa,1
, Shuai Chena
, Hiu Yan Wonga, Chi-Kin Wonga,
Liwen Jiangb,c,d,e, and Kam-Bo Wonga,2
aCentre for Protein Science and Crystallography, School of Lif... |
7F2N | Crystal structure of SSB from Klebsiella pneumonia. |
International Journal of
Molecular Sciences
Article
Characterization of the Chimeric PriB-SSBc Protein
En-Shyh Lin 1
, Yen-Hua Huang 2
and Cheng-Yang Huang 2,3,*
Citation: Lin, E.-S.; Huang, Y.-H.;
Huang, C.-Y. Characterization of the
Chimeric PriB-SSBc Protein. Int. J.
Mol. Sci. 2021, 22, 10854. h... |
7F2R | Crystal structure of VinK-VinL covalent complex formed with a pantetheineamide cross-linking probe | research communications
294
https://doi.org/10.1107/S2053230X21008761
Acta Cryst. (2021). F77, 294–302
Received 29 June 2021
Accepted 22 August 2021
Edited by S. Sheriff, Bristol-Myers Squibb, USA
Keywords: polyketides; crystal structure;
acyltransferases; carrier proteins; natural
product biosynthesis; VinK–VinL compl... |
7F2U | FmnB complexed with ADP | Received: 29 August 2021
Revised: 5 October 2021
Accepted: 20 October 2021
DOI: 10.1002/mco2.99
O R I G I NA L A RT I C L E
Structural insights into the catalytic and inhibitory
mechanisms of the flavin transferase FmnB in Listeria
monocytogenes
Yanhui Zheng
Weizhu Yan
Chao Dou
Dan Zhou
Yunying Chen
Ying Jin
Lulu Yang
... |
7F2X | Crystal structure of MEK1 C121S mutant | ARTICLE
Qualitative differences in disease-associated MEK
mutants reveal molecular signatures and aberrant
signaling-crosstalk in cancer
Yuji Kubota1, Yuko Fujioka
2,3, Ashwini Patil4,6, Yusuke Takagi1, Daisuke Matsubara5, Masatomi Iijima2,
Isao Momose2, Ryosuke Naka1, Kenta Nakai
4, Nobuo N. Noda
2,3 & Mutsuhiro Takek... |
7F38 | Cyanophage A-1(L) capsid asymmetric unit | Capsid Structure of Anabaena Cyanophage A-1(L)
Ning Cui,a Feng Yang,a Jun-Tao Zhang,a Hui Sun,a Yu Chen,a Rong-Cheng Yu,a Zhi-Peng Chen,a Yong-Liang Jiang,a Shu-Jing Han,a
Xudong Xu,b Qiong Li,a
Cong-Zhao Zhoua
aHefei National Laboratory for Physical Sciences at the Microscale and School of Life Sciences, University of... |
7F39 | The structure of flavin transferase FmnB | Received: 29 August 2021
Revised: 5 October 2021
Accepted: 20 October 2021
DOI: 10.1002/mco2.99
O R I G I NA L A RT I C L E
Structural insights into the catalytic and inhibitory
mechanisms of the flavin transferase FmnB in Listeria
monocytogenes
Yanhui Zheng
Weizhu Yan
Chao Dou
Dan Zhou
Yunying Chen
Ying Jin
Lulu Yang
... |
7F3E | Cryo-EM structure of the minimal protein-only RNase P from Aquifex aeolicus | Minimal protein-only RNase P structure reveals insights into
tRNA precursor recognition and catalysis
Received for publication, June 18, 2021, and in revised form, July 20, 2021 Published, Papers in Press, July 31, 2021,
https://doi.org/10.1016/j.jbc.2021.101028
Takamasa Teramoto1,*,‡ , Takeshi Koyasu1,‡, Naruhiko Adac... |
7F3F | CryoEM structure of human Kv4.2-KChIP1 complex | 158 | Nature | Vol 599 | 4 November 2021
Article
Structural basis of gating modulation of Kv4
channel complexes
Yoshiaki Kise1,5 ✉, Go Kasuya2,5 ✉, Hiroyuki H. Okamoto1, Daichi Yamanouchi1, Kan Kobayashi1,3,
Tsukasa Kusakizako1, Tomohiro Nishizawa1,4, Koichi Nakajo2 & Osamu Nureki1 ✉
Modulation of voltage-gated... |
7F3G | Crystal structure of DCLK1 kinase domain in complex with ruxolitinib |
International Journal of
Molecular Sciences
Article
Structural Basis of Inhibition of DCLK1 by Ruxolitinib
Dong Man Jang †, Hyo Jin Lim †, Hyunggu Hahn
, Yeon Lee
, Hark Kyun Kim * and Hyoun Sook Kim *
Citation: Jang, D.M.; Lim, H.J.;
Hahn, H.; Lee, Y.; Kim, H.K.; Kim,
H.S. Structural Basis of Inhi... |
7F3N | Structure of PopP2 in apo form | ARTICLE
Secondary-structure switch regulates the substrate
binding of a YopJ family acetyltransferase
Yao Xia1,2,8, Rongfeng Zou3,8, Maxime Escouboué4,8, Liang Zhong1,2,8, Chengjun Zhu1,2, Cécile Pouzet5,
Xueqiang Wu6, Yongjin Wang1,2, Guohua Lv7, Haibo Zhou
6, Pinghua Sun
1,2✉, Ke Ding
1,2✉,
Laurent Deslandes
4✉, Shug... |
7F3O | Crystal structure of the GluA2o LBD in complex with glutamate and TAK-653 | 1
Vol.:(0123456789)
Scientific Reports | (2021) 11:14532
| https://doi.org/10.1038/s41598-021-93888-0
www.nature.com/scientificreports
Strictly regulated
agonist‑dependent activation
of AMPA‑R is the key characteristic
of TAK‑653 for robust synaptic
responses and cognitive
improvement
Atsushi Suzuki1, Aki... |
7F3Q | SARS-CoV-2 RBD in complex with A5-10 Fab and A34-2 Fab | Antibody Therapeutics, 2023, Vol. 6, No. 2
76–86
https://doi.org/10.1093/abt/tbad002
Advance Access Publication on 17 February 2023
Research Article
Development of neutralizing antibodies against
SARS-CoV-2, using a high-throughput single-B-cell
cloning method
Yang Dou1,†*
, Ke Xu2,†, Yong-Qiang Deng3,†, Zijing Jia4,†,... |
7F3S | Crystal structure of Sth1 Bromodomain in complex with H3K14bz peptide | ARTICLE
Global profiling of regulatory elements in the
histone benzoylation pathway
Duo Wang1,2,5, Fuxiang Yan1,2,5, Ping Wu3,5, Kexue Ge1,2, Muchun Li1,2,4, Tingting Li1,2, Ying Gao1,
Chao Peng
3✉& Yong Chen
1,2,4✉
Lysine benzoylation (Kbz) is a recently discovered post-translational modification associated
with active ... |
7F3T | Cryo-EM structure of human TMEM120A in the CoASH-bound state | *For correspondence:
zhaoy@ibp.ac.cn (YZ);
xbailong@mail.tsinghua.edu.cn
(BX);
liuzf@ibp.ac.cn (ZL)
†These authors contributed
equally to this work
Competing interests: The
authors declare that no
competing interests exist.
Funding: See page 21
Preprinted: 17 June 2021
Received: 20 June 2021
Accepted: 16 August 2021
Pu... |
7F3U | Cryo-EM structure of human TMEM120A in the CoASH-free state | *For correspondence:
zhaoy@ibp.ac.cn (YZ);
xbailong@mail.tsinghua.edu.cn
(BX);
liuzf@ibp.ac.cn (ZL)
†These authors contributed
equally to this work
Competing interests: The
authors declare that no
competing interests exist.
Funding: See page 21
Preprinted: 17 June 2021
Received: 20 June 2021
Accepted: 16 August 2021
Pu... |
7F3V | Crystal structure of YfiH with C107A mutation in complex with endogenous UDP-MurNAc | Structural Basis for the Peptidoglycan-Editing Activity of YfiH
Meng-Sheng Lee,a,b Kan-Yen Hsieh,a Chiao-I Kuo,a Szu-Hui Lee,a Shambhavi Garde,c Manjula Reddy,c
Chung-I Changa,b
aInstitute of Biological Chemistry, Academia Sinica, Taipei, Taiwan
bInstitute of Biochemical Sciences, College of Life Science, National Taiwa... |
7F3X | Lysophospholipid acyltransferase LPCAT3 in complex with lysophosphatidylcholine | ARTICLE
The structural basis for the phospholipid
remodeling by lysophosphatidylcholine
acyltransferase 3
Qing Zhang1,7, Deqiang Yao2,3,7, Bing Rao2,4,7, Liyan Jian2,4, Yang Chen2, Kexin Hu2, Ying Xia2,4, Shaobai Li2,
Yafeng Shen2, An Qin4, Jie Zhao4, Lu Zhou5, Ming Lei
2, Xian-Cheng Jiang6 & Yu Cao
2,4✉
As the major c... |
7F40 | Lysophospholipid acyltransferase LPCAT3 in a complex with Arachidonoyl-CoA | ARTICLE
The structural basis for the phospholipid
remodeling by lysophosphatidylcholine
acyltransferase 3
Qing Zhang1,7, Deqiang Yao2,3,7, Bing Rao2,4,7, Liyan Jian2,4, Yang Chen2, Kexin Hu2, Ying Xia2,4, Shaobai Li2,
Yafeng Shen2, An Qin4, Jie Zhao4, Lu Zhou5, Ming Lei
2, Xian-Cheng Jiang6 & Yu Cao
2,4✉
As the major c... |
7F49 | von Willebrand factor (VWF) A1 domain with BT-100 aptamer RNA | J Thromb Haemost. 2020;18:1113–1123.
| 1113
wileyonlinelibrary.com/journal/jth
Received: 8 December 2019 | Accepted: 29 January 2020
DOI: 10.1111/jth.14755
O R I G I N A L A R T I C L E
The development and characterization of a long acting anti-
thrombotic von Willebrand factor (VWF) aptamer
Shuhao Zhu1 |... |
7F4A | Crystal structure of Taf14 YEATS domain in complex with H3K9bz peptide | ARTICLE
Global profiling of regulatory elements in the
histone benzoylation pathway
Duo Wang1,2,5, Fuxiang Yan1,2,5, Ping Wu3,5, Kexue Ge1,2, Muchun Li1,2,4, Tingting Li1,2, Ying Gao1,
Chao Peng
3✉& Yong Chen
1,2,4✉
Lysine benzoylation (Kbz) is a recently discovered post-translational modification associated
with active ... |
7F4B | The crystal structure of the immature apo-enzyme of homoserine dehydrogenase from the hyperthermophilic archaeon Sulfurisphaera tokodaii. | ARTICLE
Conformational changes in the catalytic region are
responsible for heat-induced activation of
hyperthermophilic homoserine dehydrogenase
Tatsuya Kubota1, Erika Kurihara2, Kazuya Watanabe1, Kohei Ogata2, Ryosuke Kaneko2, Masaru Goto2,
Toshihisa Ohshima3 & Kazuaki Yoshimune1✉
When overexpressed as an immature enz... |
7F4C | The crystal structure of the immature holo-enzyme of homoserine dehydrogenase complexed with NADP and 1,4-butandiol from the hyperthermophilic archaeon Sulfurisphaera tokodaii. | ARTICLE
Conformational changes in the catalytic region are
responsible for heat-induced activation of
hyperthermophilic homoserine dehydrogenase
Tatsuya Kubota1, Erika Kurihara2, Kazuya Watanabe1, Kohei Ogata2, Ryosuke Kaneko2, Masaru Goto2,
Toshihisa Ohshima3 & Kazuaki Yoshimune1✉
When overexpressed as an immature enz... |
7F4D | Cryo-EM structure of alpha-MSH-bound melanocortin-1 receptor in complex with Gs protein and Nb35 | ARTICLE
Structural mechanism of calcium-mediated hormone
recognition and Gβ interaction by the human melanocortin-1
receptor
Shanshan Ma
1,2,7, Yan Chen1,3,4,7, Antao Dai5, Wanchao Yin
1, Jia Guo1,2, Dehua Yang
1,2,5, Fulai Zhou
1, Yi Jiang1,2,
Ming-Wei Wang
1,2,3,4,5,6✉and H. Eric Xu
1,2,6✉
© CEMCS, CAS 2021
Melanocor... |
7F4E | Crystal structure of Hst2 in complex with H3K9bz peptide | ARTICLE
Global profiling of regulatory elements in the
histone benzoylation pathway
Duo Wang1,2,5, Fuxiang Yan1,2,5, Ping Wu3,5, Kexue Ge1,2, Muchun Li1,2,4, Tingting Li1,2, Ying Gao1,
Chao Peng
3✉& Yong Chen
1,2,4✉
Lysine benzoylation (Kbz) is a recently discovered post-translational modification associated
with active ... |
7F4F | Cryo-EM structure of afamelanotide-bound melanocortin-1 receptor in complex with Gs protein and scFv16 | ARTICLE
Structural mechanism of calcium-mediated hormone
recognition and Gβ interaction by the human melanocortin-1
receptor
Shanshan Ma
1,2,7, Yan Chen1,3,4,7, Antao Dai5, Wanchao Yin
1, Jia Guo1,2, Dehua Yang
1,2,5, Fulai Zhou
1, Yi Jiang1,2,
Ming-Wei Wang
1,2,3,4,5,6✉and H. Eric Xu
1,2,6✉
© CEMCS, CAS 2021
Melanocor... |
7F4H | Cryo-EM structure of afamelanotide-bound melanocortin-1 receptor in complex with Gs protein, Nb35 and scFv16 | ARTICLE
Structural mechanism of calcium-mediated hormone
recognition and Gβ interaction by the human melanocortin-1
receptor
Shanshan Ma
1,2,7, Yan Chen1,3,4,7, Antao Dai5, Wanchao Yin
1, Jia Guo1,2, Dehua Yang
1,2,5, Fulai Zhou
1, Yi Jiang1,2,
Ming-Wei Wang
1,2,3,4,5,6✉and H. Eric Xu
1,2,6✉
© CEMCS, CAS 2021
Melanocor... |
7F4I | Cryo-EM structure of SHU9119-bound melanocortin-1 receptor in complex with Gs protein and Nb35 | ARTICLE
Structural mechanism of calcium-mediated hormone
recognition and Gβ interaction by the human melanocortin-1
receptor
Shanshan Ma
1,2,7, Yan Chen1,3,4,7, Antao Dai5, Wanchao Yin
1, Jia Guo1,2, Dehua Yang
1,2,5, Fulai Zhou
1, Yi Jiang1,2,
Ming-Wei Wang
1,2,3,4,5,6✉and H. Eric Xu
1,2,6✉
© CEMCS, CAS 2021
Melanocor... |
7F4W | Complex structure of HLA2402 with recognizing SARS-CoV-2 epitope pep4 |
Since January 2020 Elsevier has created a COVID-19 resource centre with
free information in English and Mandarin on the novel coronavirus COVID-
19. The COVID-19 resource centre is hosted on Elsevier Connect, the
company's public news and information website.
Elsevier hereby grants permission to make all its C... |
7F4Y | Crystal structure of replisomal dimer of DNA polymerase from bacteriophage RB69 with DNA duplexes | Structure of New Binary and Ternary
DNA Polymerase Complexes From
Bacteriophage RB69
Jongseo Park 1,2†, Hyung-Seop Youn 1,2,3†, Jun Yop An 1,2,4, Youngjin Lee 1,2,5,
Soo Hyun Eom 1,2,6* and Jimin Wang 2,7*
1School of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju, South Korea, 2Steitz Center... |
7F51 | Crystal structure of Hst2 in complex with 2'-O-Benzoyl ADP Ribose | ARTICLE
Global profiling of regulatory elements in the
histone benzoylation pathway
Duo Wang1,2,5, Fuxiang Yan1,2,5, Ping Wu3,5, Kexue Ge1,2, Muchun Li1,2,4, Tingting Li1,2, Ying Gao1,
Chao Peng
3✉& Yong Chen
1,2,4✉
Lysine benzoylation (Kbz) is a recently discovered post-translational modification associated
with active ... |
7F53 | Cryo-EM structure of a-MSH-MC4R-Gs_Nb35 complex | ARTICLE
Structural insights into ligand recognition and activation of the
melanocortin-4 receptor
Huibing Zhang1,2,3,4,16, Li-Nan Chen1,2,3,4,16, Dehua Yang
5,6,7,16, Chunyou Mao
1,2,3,4, Qingya Shen
1,2,3,4, Wenbo Feng8,
Dan-Dan Shen
1,2,3,4, Antao Dai5,6, Shanshan Xie
9, Yan Zhou5,6, Jiao Qin1,2,3,4, Jin-Peng Sun10,1... |
7F54 | Cryo-EM structure of afamelanotide-MC4R-Gs_Nb35 complex | ARTICLE
Structural insights into ligand recognition and activation of the
melanocortin-4 receptor
Huibing Zhang1,2,3,4,16, Li-Nan Chen1,2,3,4,16, Dehua Yang
5,6,7,16, Chunyou Mao
1,2,3,4, Qingya Shen
1,2,3,4, Wenbo Feng8,
Dan-Dan Shen
1,2,3,4, Antao Dai5,6, Shanshan Xie
9, Yan Zhou5,6, Jiao Qin1,2,3,4, Jin-Peng Sun10,1... |
7F55 | Cryo-EM structure of bremelanotide-MC4R-Gs_Nb35 complex | ARTICLE
Structural insights into ligand recognition and activation of the
melanocortin-4 receptor
Huibing Zhang1,2,3,4,16, Li-Nan Chen1,2,3,4,16, Dehua Yang
5,6,7,16, Chunyou Mao
1,2,3,4, Qingya Shen
1,2,3,4, Wenbo Feng8,
Dan-Dan Shen
1,2,3,4, Antao Dai5,6, Shanshan Xie
9, Yan Zhou5,6, Jiao Qin1,2,3,4, Jin-Peng Sun10,1... |
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