protein_name stringlengths 4 4 | structure_title stringlengths 3 322 | main_text stringlengths 0 302k |
|---|---|---|
7ET5 | Crystal structure of Arabidopsis TEM1 AP2 domain | TEM1 combinatorially binds to FLOWERING LOCUS T
and recruits a Polycomb factor to repress the
floral transition in Arabidopsis
Hongmiao Hua,b,c,1, Shu Tiana,c,1, Guohui Xieb, Rui Liub, Nana Wangb, Sisi Lib, Yuehui Hea,d,e,2, and Jiamu Dub,2
aNational Key Laboratory of Plant Molecular Genetics and Shanghai Center f... |
7ET6 | Crystal structure of Arabidopsis TEM1 B3-DNA complex | TEM1 combinatorially binds to FLOWERING LOCUS T
and recruits a Polycomb factor to repress the
floral transition in Arabidopsis
Hongmiao Hua,b,c,1, Shu Tiana,c,1, Guohui Xieb, Rui Liub, Nana Wangb, Sisi Lib, Yuehui Hea,d,e,2, and Jiamu Dub,2
aNational Key Laboratory of Plant Molecular Genetics and Shanghai Center f... |
7ET7 | Co-crystal structure of Human Nicotinamide N-methyltransferase (NNMT) with tricyclic small molecule inhibitor JBSNF-000028 | 1
Vol.:(0123456789)
Scientific Reports | (2022) 12:15440
| https://doi.org/10.1038/s41598-022-19634-2
www.nature.com/scientificreports
Novel tricyclic small molecule
inhibitors of Nicotinamide
N‑methyltransferase
for the treatment of metabolic
disorders
Sven Ruf1,7, Sridharan Rajagopal2,7, Sanjay Venkatach... |
7ET8 | Crystal structure of thermostable AbHpaI, a class II metal dependent pyruvate aldolase, HpaI from Acinetobacter baumannii | Catalytic and structural insights into a stereospecific and
thermostable Class II aldolase HpaI from Acinetobacter
baumannii
Received for publication, May 28, 2021, and in revised form, October 1, 2021 Published, Papers in Press, October 5, 2021,
https://doi.org/10.1016/j.jbc.2021.101280
Pratchaya Watthaisong1,‡, Asween... |
7ET9 | Crystal structure of AbHpaI-Zn-pyruvate complex, Class II aldolase, HpaI from Acinetobacter baumannii | Catalytic and structural insights into a stereospecific and
thermostable Class II aldolase HpaI from Acinetobacter
baumannii
Received for publication, May 28, 2021, and in revised form, October 1, 2021 Published, Papers in Press, October 5, 2021,
https://doi.org/10.1016/j.jbc.2021.101280
Pratchaya Watthaisong1,‡, Asween... |
7ETA | Crystal structure of AbHpaI-Co-pyruvate complex, Class II aldolase, HpaI from Acinetobacter baumannii | Catalytic and structural insights into a stereospecific and
thermostable Class II aldolase HpaI from Acinetobacter
baumannii
Received for publication, May 28, 2021, and in revised form, October 1, 2021 Published, Papers in Press, October 5, 2021,
https://doi.org/10.1016/j.jbc.2021.101280
Pratchaya Watthaisong1,‡, Asween... |
7ETB | Crystal structure of AbHpaI-Mn-pyruvate complex, Class II aldolase, HpaI from Acinetobacter baumannii | Catalytic and structural insights into a stereospecific and
thermostable Class II aldolase HpaI from Acinetobacter
baumannii
Received for publication, May 28, 2021, and in revised form, October 1, 2021 Published, Papers in Press, October 5, 2021,
https://doi.org/10.1016/j.jbc.2021.101280
Pratchaya Watthaisong1,‡, Asween... |
7ETC | Crystal structure of AbHpaI-Zn-(4R)-KDGal complex, Class II aldolase, HpaI from Acinetobacter baumannii | Catalytic and structural insights into a stereospecific and
thermostable Class II aldolase HpaI from Acinetobacter
baumannii
Received for publication, May 28, 2021, and in revised form, October 1, 2021 Published, Papers in Press, October 5, 2021,
https://doi.org/10.1016/j.jbc.2021.101280
Pratchaya Watthaisong1,‡, Asween... |
7ETD | Crystal structure of AbHpaI-Zn-(4S)-KDGlu complex, Class II aldolase, HpaI from Acinetobacter baumannii | Catalytic and structural insights into a stereospecific and
thermostable Class II aldolase HpaI from Acinetobacter
baumannii
Received for publication, May 28, 2021, and in revised form, October 1, 2021 Published, Papers in Press, October 5, 2021,
https://doi.org/10.1016/j.jbc.2021.101280
Pratchaya Watthaisong1,‡, Asween... |
7ETE | Crystal structure of AbHpaI-Mg-(4R)-KDGal complex, Class II aldolase, HpaI from Acinetobacter baumannii | Catalytic and structural insights into a stereospecific and
thermostable Class II aldolase HpaI from Acinetobacter
baumannii
Received for publication, May 28, 2021, and in revised form, October 1, 2021 Published, Papers in Press, October 5, 2021,
https://doi.org/10.1016/j.jbc.2021.101280
Pratchaya Watthaisong1,‡, Asween... |
7ETF | Crystal structure of AbHpaI-Mn-pyruvate-succinic semialdehyde complex, Class II aldolase, HpaI from Acinetobacter baumannii | Catalytic and structural insights into a stereospecific and
thermostable Class II aldolase HpaI from Acinetobacter
baumannii
Received for publication, May 28, 2021, and in revised form, October 1, 2021 Published, Papers in Press, October 5, 2021,
https://doi.org/10.1016/j.jbc.2021.101280
Pratchaya Watthaisong1,‡, Asween... |
7ETG | Crystal structure of AbHpaI-Co-pyruvate-succinic semialdehyde complex, Class II aldolase, HpaI from Acinetobacter baumannii | Catalytic and structural insights into a stereospecific and
thermostable Class II aldolase HpaI from Acinetobacter
baumannii
Received for publication, May 28, 2021, and in revised form, October 1, 2021 Published, Papers in Press, October 5, 2021,
https://doi.org/10.1016/j.jbc.2021.101280
Pratchaya Watthaisong1,‡, Asween... |
7ETH | Crystal structure of AbHpaI-Zn-pyruvate-propionaldehyde complex, Class II aldolase, HpaI from Acinetobacter baumannii | Catalytic and structural insights into a stereospecific and
thermostable Class II aldolase HpaI from Acinetobacter
baumannii
Received for publication, May 28, 2021, and in revised form, October 1, 2021 Published, Papers in Press, October 5, 2021,
https://doi.org/10.1016/j.jbc.2021.101280
Pratchaya Watthaisong1,‡, Asween... |
7ETI | Crystal structure of AbHpaI-Zn-pyruvate-4-hydroxybenzaldehyde complex, Class II aldolase, HpaI from Acinetobacter baumannii | Catalytic and structural insights into a stereospecific and
thermostable Class II aldolase HpaI from Acinetobacter
baumannii
Received for publication, May 28, 2021, and in revised form, October 1, 2021 Published, Papers in Press, October 5, 2021,
https://doi.org/10.1016/j.jbc.2021.101280
Pratchaya Watthaisong1,‡, Asween... |
7ETJ | C5 portal vertex in the partially-enveloped virion capsid | ARTICLE
Structural basis for genome packaging, retention,
and ejection in human cytomegalovirus
Zhihai Li
1,3, Jingjing Pang
1,2,3, Lili Dong
1,3 & Xuekui Yu
1,2✉
How the human cytomegalovirus (HCMV) genome—the largest among human herpes-
viruses—is packaged, retained, and ejected remains unclear. We present the in sit... |
7ETM | C6 portal vertex in the enveloped virion capsid | ARTICLE
Structural basis for genome packaging, retention,
and ejection in human cytomegalovirus
Zhihai Li
1,3, Jingjing Pang
1,2,3, Lili Dong
1,3 & Xuekui Yu
1,2✉
How the human cytomegalovirus (HCMV) genome—the largest among human herpes-
viruses—is packaged, retained, and ejected remains unclear. We present the in sit... |
7ETO | C1 CVSC-binding penton vertex in the virion capsid of Human Cytomegalovirus | ARTICLE
Structural basis for genome packaging, retention,
and ejection in human cytomegalovirus
Zhihai Li
1,3, Jingjing Pang
1,2,3, Lili Dong
1,3 & Xuekui Yu
1,2✉
How the human cytomegalovirus (HCMV) genome—the largest among human herpes-
viruses—is packaged, retained, and ejected remains unclear. We present the in sit... |
7ETR | Crystal structure of SO_1444-SO_1445 complex from Shewanella oneidensis | microorganisms
Article
Insights into the Neutralization and DNA Binding of
Toxin–Antitoxin System ParESO-CopASO by
Structure-Function Studies
Juan Zhou 1, Xue-Jian Du 1, Ying Liu 2, Zeng-Qiang Gao 2, Zhi Geng 2, Yu-Hui Dong 2,3,* and Heng Zhang 2,*
Citation: Zhou, J.; Du, X.-J.; Liu, Y.;
Gao, Z.-Q.; G... |
7ETT | The FK1 domain of FKBP51 in complex with peptide-inhibitor hit QFPFV | Discovery of pentapeptide-inhibitor hits targeting FKBP51 by combining
computational modeling and X-ray crystallography
Jian-Ting Han a, Yongchang Zhu a, Da-Bo Pan b, Hong-Xiang Xue c, Shuang Wang a, Yali Peng c,
Huanxiang Liu d,⇑, Yong-Xing He c,⇑, Xiaojun Yao a,e,⇑
a State Key Laboratory of Applied Organic Chemistry ... |
7ETU | The FK1 domain of FKBP51 in complex with peptide-inhibitor hit SFPFT | Discovery of pentapeptide-inhibitor hits targeting FKBP51 by combining
computational modeling and X-ray crystallography
Jian-Ting Han a, Yongchang Zhu a, Da-Bo Pan b, Hong-Xiang Xue c, Shuang Wang a, Yali Peng c,
Huanxiang Liu d,⇑, Yong-Xing He c,⇑, Xiaojun Yao a,e,⇑
a State Key Laboratory of Applied Organic Chemistry ... |
7ETV | The FK1 domain of FKBP51 in complex with peptide-inhibitor hit DFPFV | Discovery of pentapeptide-inhibitor hits targeting FKBP51 by combining
computational modeling and X-ray crystallography
Jian-Ting Han a, Yongchang Zhu a, Da-Bo Pan b, Hong-Xiang Xue c, Shuang Wang a, Yali Peng c,
Huanxiang Liu d,⇑, Yong-Xing He c,⇑, Xiaojun Yao a,e,⇑
a State Key Laboratory of Applied Organic Chemistry ... |
7EU2 | Complex structure of HLA0201 with recognizing SARS-CoV-2 epitope S1 |
Since January 2020 Elsevier has created a COVID-19 resource centre with
free information in English and Mandarin on the novel coronavirus COVID-
19. The COVID-19 resource centre is hosted on Elsevier Connect, the
company's public news and information website.
Elsevier hereby grants permission to make all its C... |
7EU5 | Co-crystal structure of Human Nicotinamide N-methyltransferase (NNMT) with tricyclic small molecule inhibitor JBSNF-000107 | 1
Vol.:(0123456789)
Scientific Reports | (2022) 12:15440
| https://doi.org/10.1038/s41598-022-19634-2
www.nature.com/scientificreports
Novel tricyclic small molecule
inhibitors of Nicotinamide
N‑methyltransferase
for the treatment of metabolic
disorders
Sven Ruf1,7, Sridharan Rajagopal2,7, Sanjay Venkatach... |
7EU9 | Crystal structure of the selenomethionine(SeMet)-derived Cas12i1 R-loop complex before target DNA cleavage | ARTICLE
Mechanistic insights into the R-loop formation and
cleavage in CRISPR-Cas12i1
Bo Zhang
1,2, Diyin Luo1,2, Yu Li1,2, Vanja Perčulija
1, Jing Chen1, Jinying Lin1, Yangmiao Ye1 &
Songying Ouyang
1✉
Cas12i is a newly identified member of the functionally diverse type V CRISPR-Cas effectors.
Although Cas12i has the p... |
7EUK | Crystal structure of N(omega)-hydroxy-L-arginine hydrolase in complex with L-Orn | F U L L - L E N G T H P A P E R
Catalytic mechanism of DcsB: Arginase framework used for
hydrolyzing its inhibitor
Kosuke Oda1
|
Takemasa Sakaguchi1
|
Yasuyuki Matoba2
1Department of Virology, Institute of
Biomedical and Health Sciences,
Hiroshima University, Hiroshima, Japan
2Faculty of Pharmacy, Yasuda Women's
Univer... |
7EUL | Crystal structure of C86H-H196S mutant of N(omega)-hydroxy-L-arginine hydrolase | F U L L - L E N G T H P A P E R
Catalytic mechanism of DcsB: Arginase framework used for
hydrolyzing its inhibitor
Kosuke Oda1
|
Takemasa Sakaguchi1
|
Yasuyuki Matoba2
1Department of Virology, Institute of
Biomedical and Health Sciences,
Hiroshima University, Hiroshima, Japan
2Faculty of Pharmacy, Yasuda Women's
Univer... |
7EUN | Crystal structure of N(omega)-hydroxy-L-arginine hydrolase in complex with ABH | F U L L - L E N G T H P A P E R
Catalytic mechanism of DcsB: Arginase framework used for
hydrolyzing its inhibitor
Kosuke Oda1
|
Takemasa Sakaguchi1
|
Yasuyuki Matoba2
1Department of Virology, Institute of
Biomedical and Health Sciences,
Hiroshima University, Hiroshima, Japan
2Faculty of Pharmacy, Yasuda Women's
Univer... |
7EUO | The structure of formyl peptide receptor 1 in complex with Gi and peptide agonist fMLF | nature communications
Article
https://doi.org/10.1038/s41467-022-32822-y
Structural basis for recognition of N-formyl
peptides as pathogen-associated molecular
patterns
Geng Chen1,8, Xiankun Wang
1,8, Qiwen Liao
1,8, Yunjun Ge
1,2,8,
Haizhan Jiao1,2, Qiang Chen1, Yezhou Liu
1,3, Wenping Lyu4, Lizhe Zhu
4,
Gydo C. P. va... |
7EUQ | Crystal structure of C86H-Y124N-G126H-H196S mutant of N(omega)-hydroxy-L-arginine hydrolase | F U L L - L E N G T H P A P E R
Catalytic mechanism of DcsB: Arginase framework used for
hydrolyzing its inhibitor
Kosuke Oda1
|
Takemasa Sakaguchi1
|
Yasuyuki Matoba2
1Department of Virology, Institute of
Biomedical and Health Sciences,
Hiroshima University, Hiroshima, Japan
2Faculty of Pharmacy, Yasuda Women's
Univer... |
7EUX | Crystal structure of the Lon-like protease MtaLonC with D581A mutation in complex with substrate polypeptide | Li et al., Sci. Adv. 7, eabj9537 (2021) 10 November 2021
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 10
ST RUCTURAL B IOL OG Y
Processive cleavage of substrate at individual
proteolytic active sites of the Lon protease complex
Shanshan Li1†, Kan-Yen Hsieh2†, Chiao-I Kuo2, Shih-Chieh Su2, Kai-Fa Huang2, ... |
7EUY | Crystal structure of the Lon-like protease MtaLonC with D582A mutation in complex with substrate polypeptide | Li et al., Sci. Adv. 7, eabj9537 (2021) 10 November 2021
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 10
ST RUCTURAL B IOL OG Y
Processive cleavage of substrate at individual
proteolytic active sites of the Lon protease complex
Shanshan Li1†, Kan-Yen Hsieh2†, Chiao-I Kuo2, Shih-Chieh Su2, Kai-Fa Huang2, ... |
7EV1 | Crystal structure of LI-Cadherin EC1-2 | Mechanism of dimerization and structural features of human
LI-cadherin
Received for publication, June 5, 2021, and in revised form, July 2, 2021 Published, Papers in Press, August 6, 2021,
https://doi.org/10.1016/j.jbc.2021.101054
Anna Yui1 , Jose M. M. Caaveiro1,2,* , Daisuke Kuroda1,3 , Makoto Nakakido1, Satoru Nagat... |
7EV4 | Crystal structure of the Lon-like protease MtaLonC with S582A mutation in complex with F-b20-Q | Li et al., Sci. Adv. 7, eabj9537 (2021) 10 November 2021
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 10
ST RUCTURAL B IOL OG Y
Processive cleavage of substrate at individual
proteolytic active sites of the Lon protease complex
Shanshan Li1†, Kan-Yen Hsieh2†, Chiao-I Kuo2, Shih-Chieh Su2, Kai-Fa Huang2, ... |
7EV5 | Crystal structure of BLEG-1 B3 metallo-beta-lactamase |
International Journal of
Molecular Sciences
Article
Dual Activity BLEG-1 from Bacillus lehensis G1 Revealed
Structural Resemblance to B3 Metallo-β-Lactamase
and Glyoxalase II: An Insight into Its Enzyme Promiscuity
and Evolutionary Divergence
Shaw Xian Au 1,2
, Nur Syazana Dzulkifly 2, Noor Dina Muhd Noor 1,3, Hiroyo... |
7EV6 | Crystal structure of the Lon-like protease MtaLonC with D581A mutation in complex with F-b20-Q | Li et al., Sci. Adv. 7, eabj9537 (2021) 10 November 2021
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 10
ST RUCTURAL B IOL OG Y
Processive cleavage of substrate at individual
proteolytic active sites of the Lon protease complex
Shanshan Li1†, Kan-Yen Hsieh2†, Chiao-I Kuo2, Shih-Chieh Su2, Kai-Fa Huang2, ... |
7EV8 | Structure of Human Parainfluenza Virus 3 Unassembled Nucleoprotein in Complex with its viral chaperone | Structural Basis of Human Parainfluenza Virus 3 Unassembled
Nucleoprotein in Complex with Its Viral Chaperone
Xiaofei Dong,a Xue Wang,a Mengjia Xie,a Wei Wu,a
Zhongzhou Chena
aState Key Laboratory of Agrobiotechnology and Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Biological Scien... |
7EVB | Odinarchaeota tubulin (OdinTubulin) H393D mutant, in a protofilament arrangement, bound to 77% GTP/23% and 2 Na+ | Akıl et al., Sci. Adv. 8, eabm2225 (2022) 25 March 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 12
C EL L B IOLOGY
Structure and dynamics of Odinarchaeota
tubulin and the implications for eukaryotic
microtubule evolution
Caner Akıl1,2†, Samson Ali1,3†, Linh T. Tran1†, Jérémie Gaillard4, Wenfei Li... |
7EVC | Odinarchaeota tubulin (OdinTubulin) H393D mutant, in a protofilament arrangement, bound to 60% GTP/40% GDP and 2 Na+ | Akıl et al., Sci. Adv. 8, eabm2225 (2022) 25 March 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 12
C EL L B IOLOGY
Structure and dynamics of Odinarchaeota
tubulin and the implications for eukaryotic
microtubule evolution
Caner Akıl1,2†, Samson Ali1,3†, Linh T. Tran1†, Jérémie Gaillard4, Wenfei Li... |
7EVD | Odinarchaeota tubulin (OdinTubulin) H393D mutant, in a protofilament arrangement, bound to 53% GTP/47% and 2 Na+ | Akıl et al., Sci. Adv. 8, eabm2225 (2022) 25 March 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 12
C EL L B IOLOGY
Structure and dynamics of Odinarchaeota
tubulin and the implications for eukaryotic
microtubule evolution
Caner Akıl1,2†, Samson Ali1,3†, Linh T. Tran1†, Jérémie Gaillard4, Wenfei Li... |
7EVE | Odinarchaeota tubulin (OdinTubulin) H393D mutant, in a protofilament arrangement, bound to 100% GDP and 2 Na+ | Akıl et al., Sci. Adv. 8, eabm2225 (2022) 25 March 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 12
C EL L B IOLOGY
Structure and dynamics of Odinarchaeota
tubulin and the implications for eukaryotic
microtubule evolution
Caner Akıl1,2†, Samson Ali1,3†, Linh T. Tran1†, Jérémie Gaillard4, Wenfei Li... |
7EVG | Apo Odinarchaeota tubulin (OdinTubulin) H393D mutant, in a psuedo-protofilament arrangement | Akıl et al., Sci. Adv. 8, eabm2225 (2022) 25 March 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 12
C EL L B IOLOGY
Structure and dynamics of Odinarchaeota
tubulin and the implications for eukaryotic
microtubule evolution
Caner Akıl1,2†, Samson Ali1,3†, Linh T. Tran1†, Jérémie Gaillard4, Wenfei Li... |
7EVH | Odinarchaeota tubulin H393D mutant, in a psuedo protofilament arrangement, bound to 59% GDP, 41% phosphate | Akıl et al., Sci. Adv. 8, eabm2225 (2022) 25 March 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 12
C EL L B IOLOGY
Structure and dynamics of Odinarchaeota
tubulin and the implications for eukaryotic
microtubule evolution
Caner Akıl1,2†, Samson Ali1,3†, Linh T. Tran1†, Jérémie Gaillard4, Wenfei Li... |
7EVI | Odinarchaeota tubulin (OdinTubulin) H393D mutant, in a protofilament arrangement, bound to 79% GTP, 21% GDP, Na+, Mg2+ | Akıl et al., Sci. Adv. 8, eabm2225 (2022) 25 March 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 12
C EL L B IOLOGY
Structure and dynamics of Odinarchaeota
tubulin and the implications for eukaryotic
microtubule evolution
Caner Akıl1,2†, Samson Ali1,3†, Linh T. Tran1†, Jérémie Gaillard4, Wenfei Li... |
7EVK | Odinarchaeota tubulin (OdinTubulin) H393D mutant, in a protofilament arrangement, bound to 78% GTP, 22% GDP, Na+ | Akıl et al., Sci. Adv. 8, eabm2225 (2022) 25 March 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 12
C EL L B IOLOGY
Structure and dynamics of Odinarchaeota
tubulin and the implications for eukaryotic
microtubule evolution
Caner Akıl1,2†, Samson Ali1,3†, Linh T. Tran1†, Jérémie Gaillard4, Wenfei Li... |
7EVL | Odinarchaeota tubulin (OdinTubulin) H393D mutant, in a protofilament arrangement, bound to 64% GTP/36% GDP and 2 Na+ in a small unit cell | Akıl et al., Sci. Adv. 8, eabm2225 (2022) 25 March 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 12
C EL L B IOLOGY
Structure and dynamics of Odinarchaeota
tubulin and the implications for eukaryotic
microtubule evolution
Caner Akıl1,2†, Samson Ali1,3†, Linh T. Tran1†, Jérémie Gaillard4, Wenfei Li... |
7EVM | Cryo-EM structure of the compound 2-bound human GLP-1 receptor-Gs complex | ARTICLE
Molecular insights into ago-allosteric modulation of
the human glucagon-like peptide-1 receptor
Zhaotong Cong1,2,13, Li-Nan Chen3,13, Honglei Ma2,13, Qingtong Zhou4,13, Xinyu Zou5, Chenyu Ye1,2, Antao Dai6,
Qing Liu
6, Wei Huang7, Xianqiang Sun7, Xi Wang2,8, Peiyu Xu
2, Lihua Zhao2, Tian Xia5, Wenge Zhong7,
Deh... |
7EVP | Cryo-EM structure of the Gp168-beta-clamp complex | Published online 6 October 2021
Nucleic Acids Research, 2021, Vol. 49, No. 19
11367–11378
https://doi.org/10.1093/nar/gkab875
Bacteriophage Twort protein Gp168 is a -clamp
inhibitor by occupying the DNA sliding channel
Bing Liu
1,2,*,†, Shanshan Li3,†, Yang Liu1,†, Huan Chen1, Zhenyue Hu1, Zhihao Wang1,2,
Yimin Zhao4,... |
7EVR | Crystal structure of hnRNP L RRM2 in complex with SETD2 | ARTICLE
Structural basis of the interaction between SETD2
methyltransferase and hnRNP L paralogs for
governing co-transcriptional splicing
Saikat Bhattacharya
1,5, Suman Wang2,3,5, Divya Reddy1, Siyuan Shen2,3, Ying Zhang1, Ning Zhang1, Hua Li1,
Michael P. Washburn
4, Laurence Florens
1, Yunyu Shi2,3, Jerry L. Workman
... |
7EVS | Crystal structure of hnRNP LL RRM2 in complex with SETD2 | ARTICLE
Structural basis of the interaction between SETD2
methyltransferase and hnRNP L paralogs for
governing co-transcriptional splicing
Saikat Bhattacharya
1,5, Suman Wang2,3,5, Divya Reddy1, Siyuan Shen2,3, Ying Zhang1, Ning Zhang1, Hua Li1,
Michael P. Washburn
4, Laurence Florens
1, Yunyu Shi2,3, Jerry L. Workman
... |
7EVT | Crystal structure of the N-terminal degron-truncated human glutamine synthetase | research communications
Acta Cryst. (2021). F77, 427–434
https://doi.org/10.1107/S2053230X21010748
427
Received 6 July 2021
Accepted 16 October 2021
Edited by A. Nakagawa, Osaka University, Japan
Keywords: glutamine synthetase; N-terminal
degron; crystal structure.
PDB reference: N-terminal degron-truncated
human gluta... |
7EVU | Co-crystal Structure of Toxoplasma gondii Prolyl tRNA Synthetase (TgPRS) in complex with HFG and JE6 | RESEARCH ARTICLE
Double drugging of prolyl-tRNA synthetase
provides a new paradigm for anti-infective
drug development
Yogavel Manickam1☯, Nipun MalhotraID1☯¤, Siddhartha MishraID1,2,3☯, Palak Babbar1☯,
Abhishek DusaneID1, Benoıˆt Laleu4, Valeria BelliniID5, Mohamed-Ali Hakimi5,
Alexandre Bougdour5*, Amit SharmaID1,2,3... |
7EVV | Co-crystal Structure of Toxoplasma gondii Prolyl tRNA Synthetase (TgPRS) in complex with JE6 and L-pro | RESEARCH ARTICLE
Double drugging of prolyl-tRNA synthetase
provides a new paradigm for anti-infective
drug development
Yogavel Manickam1☯, Nipun MalhotraID1☯¤, Siddhartha MishraID1,2,3☯, Palak Babbar1☯,
Abhishek DusaneID1, Benoıˆt Laleu4, Valeria BelliniID5, Mohamed-Ali Hakimi5,
Alexandre Bougdour5*, Amit SharmaID1,2,3... |
7EVY | Cryo-EM structure of siponimod -bound Sphingosine-1-phosphate receptor 1 in complex with Gi protein | ARTICLE
Structures of signaling complexes of lipid receptors S1PR1 and
S1PR5 reveal mechanisms of activation and drug recognition
Yuan Yuan1,4, Guowen Jia1,4, Chao Wu1,4, Wei Wang1,4, Lin Cheng1, Qian Li1, Ziyan Li1, Kaidong Luo1, Shengyong Yang1, Wei Yan1,2✉,
Zhaoming Su
1,3✉and Zhenhua Shao
1,2✉
© CEMCS, CAS 2021
Sph... |
7EVZ | Cryo-EM structure of cenerimod -bound Sphingosine-1-phosphate receptor 1 in complex with Gi protein | ARTICLE
Structures of signaling complexes of lipid receptors S1PR1 and
S1PR5 reveal mechanisms of activation and drug recognition
Yuan Yuan1,4, Guowen Jia1,4, Chao Wu1,4, Wei Wang1,4, Lin Cheng1, Qian Li1, Ziyan Li1, Kaidong Luo1, Shengyong Yang1, Wei Yan1,2✉,
Zhaoming Su
1,3✉and Zhenhua Shao
1,2✉
© CEMCS, CAS 2021
Sph... |
7EW0 | Cryo-EM structure of ozanimod -bound Sphingosine-1-phosphate receptor 1 in complex with Gi protein | ARTICLE
Structures of signaling complexes of lipid receptors S1PR1 and
S1PR5 reveal mechanisms of activation and drug recognition
Yuan Yuan1,4, Guowen Jia1,4, Chao Wu1,4, Wei Wang1,4, Lin Cheng1, Qian Li1, Ziyan Li1, Kaidong Luo1, Shengyong Yang1, Wei Yan1,2✉,
Zhaoming Su
1,3✉and Zhenhua Shao
1,2✉
© CEMCS, CAS 2021
Sph... |
7EW1 | Cryo-EM structure of siponimod -bound Sphingosine-1-phosphate receptor 5 in complex with Gi protein | ARTICLE
Structures of signaling complexes of lipid receptors S1PR1 and
S1PR5 reveal mechanisms of activation and drug recognition
Yuan Yuan1,4, Guowen Jia1,4, Chao Wu1,4, Wei Wang1,4, Lin Cheng1, Qian Li1, Ziyan Li1, Kaidong Luo1, Shengyong Yang1, Wei Yan1,2✉,
Zhaoming Su
1,3✉and Zhenhua Shao
1,2✉
© CEMCS, CAS 2021
Sph... |
7EW2 | Cryo-EM structure of pFTY720-bound Sphingosine 1-phosphate receptor 3 in complex with Gi protein | LETTER TO THE EDITOR
Structural insights into sphingosine-1-phosphate recognition
and ligand selectivity of S1PR3–Gi signaling complexes
© CEMCS, CAS 2021
Cell Research (2022) 32:218–221; https://doi.org/10.1038/s41422-021-00567-w
Dear Editor,
Lipids are essential for all life on earth and play critical roles in
energy... |
7EW3 | Cryo-EM structure of S1P-bound Sphingosine 1-phosphate receptor 3 in complex with Gi protein | LETTER TO THE EDITOR
Structural insights into sphingosine-1-phosphate recognition
and ligand selectivity of S1PR3–Gi signaling complexes
© CEMCS, CAS 2021
Cell Research (2022) 32:218–221; https://doi.org/10.1038/s41422-021-00567-w
Dear Editor,
Lipids are essential for all life on earth and play critical roles in
energy... |
7EW4 | Cryo-EM structure of CYM-5541-bound Sphingosine 1-phosphate receptor 3 in complex with Gi protein | LETTER TO THE EDITOR
Structural insights into sphingosine-1-phosphate recognition
and ligand selectivity of S1PR3–Gi signaling complexes
© CEMCS, CAS 2021
Cell Research (2022) 32:218–221; https://doi.org/10.1038/s41422-021-00567-w
Dear Editor,
Lipids are essential for all life on earth and play critical roles in
energy... |
7EW7 | Cryo-EM structure of SEW2871-bound Sphingosine-1-phosphate receptor 1 in complex with Gi protein | ARTICLE
Structures of signaling complexes of lipid receptors S1PR1 and
S1PR5 reveal mechanisms of activation and drug recognition
Yuan Yuan1,4, Guowen Jia1,4, Chao Wu1,4, Wei Wang1,4, Lin Cheng1, Qian Li1, Ziyan Li1, Kaidong Luo1, Shengyong Yang1, Wei Yan1,2✉,
Zhaoming Su
1,3✉and Zhenhua Shao
1,2✉
© CEMCS, CAS 2021
Sph... |
7EW8 | Legionella pneumophila effector AnkD | M I CROB IOLOGY
Atypical Legionella GTPase effector hijacks host
vesicular transport factor p115 to regulate host
lipid droplet
Tao-Tao Chen1,2†, Yanling Lin1†, Shijun Zhang1†, Shuxin Liu3, Lei Song3, Wenhong Zhong2,
Zhao-Qing Luo4*, Aidong Han1*
The intracellular bacterial pathogen Legionella pneumophila uses h... |
7EW9 | GDP-bound KRAS G12D in complex with TH-Z816 | Mao et al. Cell Discovery (2022) 8:5
Cell Discovery
https://doi.org/10.1038/s41421-021-00368-w
www.nature.com/celldisc
A R T I C L E
O p e n A c c e s s
KRAS(G12D) can be targeted by potent inhibitors
via formation of salt bridge
Zhongwei Mao1, Hongying Xiao1,2, Panpan Shen3, Yu Yang3, Jing Xue1, Yunyun Yang1, Yanguo... |
7EWA | GDP-bound KRAS G12D in complex with TH-Z827 | Mao et al. Cell Discovery (2022) 8:5
Cell Discovery
https://doi.org/10.1038/s41421-021-00368-w
www.nature.com/celldisc
A R T I C L E
O p e n A c c e s s
KRAS(G12D) can be targeted by potent inhibitors
via formation of salt bridge
Zhongwei Mao1, Hongying Xiao1,2, Panpan Shen3, Yu Yang3, Jing Xue1, Yunyun Yang1, Yanguo... |
7EWB | GDP-bound KRAS G12D in complex with TH-Z835 | Mao et al. Cell Discovery (2022) 8:5
Cell Discovery
https://doi.org/10.1038/s41421-021-00368-w
www.nature.com/celldisc
A R T I C L E
O p e n A c c e s s
KRAS(G12D) can be targeted by potent inhibitors
via formation of salt bridge
Zhongwei Mao1, Hongying Xiao1,2, Panpan Shen3, Yu Yang3, Jing Xue1, Yunyun Yang1, Yanguo... |
7EWC | Mycobacterium tuberculosis HigA2 (Form I) | research papers
IUCrJ (2021). 8, 823–832
https://doi.org/10.1107/S2052252521007715
823
IUCrJ
ISSN 2052-2525
BIOLOGYjMEDICINE
Received 26 May 2021
Accepted 28 July 2021
Edited by Z.-J. Liu, Chinese Academy of
Sciences, China
Keywords: toxin–antitoxin systems;
Mycobacterium tuberculosis; transcription
factors; HigBA; Hig... |
7EWD | Mycobacterium tuberculosis HigA2 (Form II) | research papers
IUCrJ (2021). 8, 823–832
https://doi.org/10.1107/S2052252521007715
823
IUCrJ
ISSN 2052-2525
BIOLOGYjMEDICINE
Received 26 May 2021
Accepted 28 July 2021
Edited by Z.-J. Liu, Chinese Academy of
Sciences, China
Keywords: toxin–antitoxin systems;
Mycobacterium tuberculosis; transcription
factors; HigBA; Hig... |
7EWE | Mycobacterium tuberculosis HigA2 (Form III) | research papers
IUCrJ (2021). 8, 823–832
https://doi.org/10.1107/S2052252521007715
823
IUCrJ
ISSN 2052-2525
BIOLOGYjMEDICINE
Received 26 May 2021
Accepted 28 July 2021
Edited by Z.-J. Liu, Chinese Academy of
Sciences, China
Keywords: toxin–antitoxin systems;
Mycobacterium tuberculosis; transcription
factors; HigBA; Hig... |
7EWF | Selenomethionine-substituted structure of S. cerevisiae Csn12 in complex with Thp3 and Sem1 | 8882–8897
Nucleic Acids Research, 2022, Vol. 50, No. 15
Published online 29 July 2022
https://doi.org/10.1093/nar/gkac634
Structural assembly of the nucleic-acid-binding
Thp3–Csn12–Sem1 complex functioning in mRNA
splicing
Zhiling Kuang1,2, Jiyuan Ke
3,*, Jiong Hong
2, Zhongliang Zhu1,2,* and Liwen Niu1,2,*
1Hefei Nati... |
7EWI | Toxin protein from Staphylococcus aureus | Published online 10 February 2022
Nucleic Acids Research, 2022, Vol. 50, No. 4
2319–2333
https://doi.org/10.1093/nar/gkab1288
Role of PemI in the Staphylococcus aureus PemIK
toxin–antitoxin complex: PemI controls PemK by
acting as a PemK loop mimic
Do-Hee Kim
1,2,3,†, Sung-Min Kang
4,†, Sung-Min Baek3, Hye-Jin Yoon5, D... |
7EWJ | Toxin-antitoxin complex from Staphylococcus aureus | Published online 10 February 2022
Nucleic Acids Research, 2022, Vol. 50, No. 4
2319–2333
https://doi.org/10.1093/nar/gkab1288
Role of PemI in the Staphylococcus aureus PemIK
toxin–antitoxin complex: PemI controls PemK by
acting as a PemK loop mimic
Do-Hee Kim
1,2,3,†, Sung-Min Kang
4,†, Sung-Min Baek3, Hye-Jin Yoon5, D... |
7EWL | cryo-EM structure of apo GPR158 | ARTICLE
Structure of the class C orphan GPCR GPR158 in
complex with RGS7-Gβ5
Eunyoung Jeong
1,2, Yoojoong Kim
1,2, Jihong Jeong
1 & Yunje Cho
1✉
GPR158, a class C orphan GPCR, functions in cognition, stress-induced mood control, and
synaptic development. Among class C GPCRs, GPR158 is unique as it lacks a Venus flytrap-... |
7EWM | Native crystal structure of S. cerevisiae Csn12 in complex with Thp3 and Sem1 | 8882–8897
Nucleic Acids Research, 2022, Vol. 50, No. 15
Published online 29 July 2022
https://doi.org/10.1093/nar/gkac634
Structural assembly of the nucleic-acid-binding
Thp3–Csn12–Sem1 complex functioning in mRNA
splicing
Zhiling Kuang1,2, Jiyuan Ke
3,*, Jiong Hong
2, Zhongliang Zhu1,2,* and Liwen Niu1,2,*
1Hefei Nati... |
7EWP | Cryo-EM structure of human GPR158 in complex with RGS7-Gbeta5 in a 2:1:1 ratio | ARTICLE
Structure of the class C orphan GPCR GPR158 in
complex with RGS7-Gβ5
Eunyoung Jeong
1,2, Yoojoong Kim
1,2, Jihong Jeong
1 & Yunje Cho
1✉
GPR158, a class C orphan GPCR, functions in cognition, stress-induced mood control, and
synaptic development. Among class C GPCRs, GPR158 is unique as it lacks a Venus flytrap-... |
7EWQ | Structure of Mumps virus nucleocapsid ring | ARTICLE
Structural plasticity of mumps virus nucleocapsids
with cryo-EM structures
Hong Shan1,2,7, Xin Su1,7, Tianhao Li1,7, Yuqi Qin1,7, Na Zhang1,3, Liuyan Yang4,5, Linsha Ma6, Yun Bai6, Lei Qi2,
Yunhui Liu1 & Qing-Tao Shen
1,2✉
Mumps virus (MuV) is a highly contagious human pathogen and frequently causes world-
wide... |
7EWR | Cryo-EM structure of human GPR158 in complex with RGS7-Gbeta5 in a 2:2:2 ratio | ARTICLE
Structure of the class C orphan GPCR GPR158 in
complex with RGS7-Gβ5
Eunyoung Jeong
1,2, Yoojoong Kim
1,2, Jihong Jeong
1 & Yunje Cho
1✉
GPR158, a class C orphan GPCR, functions in cognition, stress-induced mood control, and
synaptic development. Among class C GPCRs, GPR158 is unique as it lacks a Venus flytrap-... |
7EWT | The crystal structure of Lysophospholipid acyltransferase LPCAT3 (MOBAT5) in its monomeric and apo form | ARTICLE
The structural basis for the phospholipid
remodeling by lysophosphatidylcholine
acyltransferase 3
Qing Zhang1,7, Deqiang Yao2,3,7, Bing Rao2,4,7, Liyan Jian2,4, Yang Chen2, Kexin Hu2, Ying Xia2,4, Shaobai Li2,
Yafeng Shen2, An Qin4, Jie Zhao4, Lu Zhou5, Ming Lei
2, Xian-Cheng Jiang6 & Yu Cao
2,4✉
As the major c... |
7EWU | Crystal structure of Ebinur Lake virus cap snatching endonuclease (WT) | Insights into Two-Metal-Ion Catalytic Mechanism of Cap-
Snatching Endonuclease of Ebinur Lake Virus in Bunyavirales
Wenhua Kuang,a Huanyu Zhang,b Yan Cai,c,e Guilin Zhang,d
Fei Deng,b Hailong Li,d Zhihong Hu,b
Yu Guo,c Manli Wang,b
Yiwu Zhou,a
Peng Gongf,g
aDepartment of Forensic Medicine, Tongji Medical College, Huazh... |
7EWV | Crystal structure of Ebinur Lake virus cap snatching endonuclease (H34A mutant) | Insights into Two-Metal-Ion Catalytic Mechanism of Cap-
Snatching Endonuclease of Ebinur Lake Virus in Bunyavirales
Wenhua Kuang,a Huanyu Zhang,b Yan Cai,c,e Guilin Zhang,d
Fei Deng,b Hailong Li,d Zhihong Hu,b
Yu Guo,c Manli Wang,b
Yiwu Zhou,a
Peng Gongf,g
aDepartment of Forensic Medicine, Tongji Medical College, Huazh... |
7EWW | Crystal structure of Ebinur Lake virus cap snatching endonuclease (N52A mutant) | Insights into Two-Metal-Ion Catalytic Mechanism of Cap-
Snatching Endonuclease of Ebinur Lake Virus in Bunyavirales
Wenhua Kuang,a Huanyu Zhang,b Yan Cai,c,e Guilin Zhang,d
Fei Deng,b Hailong Li,d Zhihong Hu,b
Yu Guo,c Manli Wang,b
Yiwu Zhou,a
Peng Gongf,g
aDepartment of Forensic Medicine, Tongji Medical College, Huazh... |
7EWX | Crystal structure of Ebinur Lake virus cap snatching endonuclease (P78A mutant) | Insights into Two-Metal-Ion Catalytic Mechanism of Cap-
Snatching Endonuclease of Ebinur Lake Virus in Bunyavirales
Wenhua Kuang,a Huanyu Zhang,b Yan Cai,c,e Guilin Zhang,d
Fei Deng,b Hailong Li,d Zhihong Hu,b
Yu Guo,c Manli Wang,b
Yiwu Zhou,a
Peng Gongf,g
aDepartment of Forensic Medicine, Tongji Medical College, Huazh... |
7EWY | Crystal structure of Ebinur Lake virus cap snatching endonuclease (D79A mutant) | Insights into Two-Metal-Ion Catalytic Mechanism of Cap-
Snatching Endonuclease of Ebinur Lake Virus in Bunyavirales
Wenhua Kuang,a Huanyu Zhang,b Yan Cai,c,e Guilin Zhang,d
Fei Deng,b Hailong Li,d Zhihong Hu,b
Yu Guo,c Manli Wang,b
Yiwu Zhou,a
Peng Gongf,g
aDepartment of Forensic Medicine, Tongji Medical College, Huazh... |
7EWZ | Crystal structure of Ebinur Lake virus cap snatching endonuclease (D92A mutant) | Insights into Two-Metal-Ion Catalytic Mechanism of Cap-
Snatching Endonuclease of Ebinur Lake Virus in Bunyavirales
Wenhua Kuang,a Huanyu Zhang,b Yan Cai,c,e Guilin Zhang,d
Fei Deng,b Hailong Li,d Zhihong Hu,b
Yu Guo,c Manli Wang,b
Yiwu Zhou,a
Peng Gongf,g
aDepartment of Forensic Medicine, Tongji Medical College, Huazh... |
7EX0 | Crystal structure of Ebinur Lake virus cap snatching endonuclease (K108A mutant) | Insights into Two-Metal-Ion Catalytic Mechanism of Cap-
Snatching Endonuclease of Ebinur Lake Virus in Bunyavirales
Wenhua Kuang,a Huanyu Zhang,b Yan Cai,c,e Guilin Zhang,d
Fei Deng,b Hailong Li,d Zhihong Hu,b
Yu Guo,c Manli Wang,b
Yiwu Zhou,a
Peng Gongf,g
aDepartment of Forensic Medicine, Tongji Medical College, Huazh... |
7EX1 | Crystal structure of Ebinur Lake virus cap snatching endonuclease (Y109A mutant) | Insights into Two-Metal-Ion Catalytic Mechanism of Cap-
Snatching Endonuclease of Ebinur Lake Virus in Bunyavirales
Wenhua Kuang,a Huanyu Zhang,b Yan Cai,c,e Guilin Zhang,d
Fei Deng,b Hailong Li,d Zhihong Hu,b
Yu Guo,c Manli Wang,b
Yiwu Zhou,a
Peng Gongf,g
aDepartment of Forensic Medicine, Tongji Medical College, Huazh... |
7EX2 | Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with L-742,001 (methyl ester form) | Structural and Biochemical Basis for Development of Diketo
Acid Inhibitors Targeting the Cap-Snatching Endonuclease of
the Ebinur Lake Virus (Order: Bunyavirales)
Wenhua Kuang,a,b Huanyu Zhang,b Yan Cai,c,e Guilin Zhang,d
Fei Deng,b Hailong Li,d Yiwu Zhou,a Manli Wang,b
Peng Gong,f,g
Yu Guo,c
Zhihong Hub
aDepartment of... |
7EX3 | Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 3 | Structural and Biochemical Basis for Development of Diketo
Acid Inhibitors Targeting the Cap-Snatching Endonuclease of
the Ebinur Lake Virus (Order: Bunyavirales)
Wenhua Kuang,a,b Huanyu Zhang,b Yan Cai,c,e Guilin Zhang,d
Fei Deng,b Hailong Li,d Yiwu Zhou,a Manli Wang,b
Peng Gong,f,g
Yu Guo,c
Zhihong Hub
aDepartment of... |
7EX4 | Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 5 | Structural and Biochemical Basis for Development of Diketo
Acid Inhibitors Targeting the Cap-Snatching Endonuclease of
the Ebinur Lake Virus (Order: Bunyavirales)
Wenhua Kuang,a,b Huanyu Zhang,b Yan Cai,c,e Guilin Zhang,d
Fei Deng,b Hailong Li,d Yiwu Zhou,a Manli Wang,b
Peng Gong,f,g
Yu Guo,c
Zhihong Hub
aDepartment of... |
7EX6 | Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 11 | Structural and Biochemical Basis for Development of Diketo
Acid Inhibitors Targeting the Cap-Snatching Endonuclease of
the Ebinur Lake Virus (Order: Bunyavirales)
Wenhua Kuang,a,b Huanyu Zhang,b Yan Cai,c,e Guilin Zhang,d
Fei Deng,b Hailong Li,d Yiwu Zhou,a Manli Wang,b
Peng Gong,f,g
Yu Guo,c
Zhihong Hub
aDepartment of... |
7EX7 | Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 16 | Structural and Biochemical Basis for Development of Diketo
Acid Inhibitors Targeting the Cap-Snatching Endonuclease of
the Ebinur Lake Virus (Order: Bunyavirales)
Wenhua Kuang,a,b Huanyu Zhang,b Yan Cai,c,e Guilin Zhang,d
Fei Deng,b Hailong Li,d Yiwu Zhou,a Manli Wang,b
Peng Gong,f,g
Yu Guo,c
Zhihong Hub
aDepartment of... |
7EX8 | Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 27 | Structural and Biochemical Basis for Development of Diketo
Acid Inhibitors Targeting the Cap-Snatching Endonuclease of
the Ebinur Lake Virus (Order: Bunyavirales)
Wenhua Kuang,a,b Huanyu Zhang,b Yan Cai,c,e Guilin Zhang,d
Fei Deng,b Hailong Li,d Yiwu Zhou,a Manli Wang,b
Peng Gong,f,g
Yu Guo,c
Zhihong Hub
aDepartment of... |
7EX9 | Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 28 | Structural and Biochemical Basis for Development of Diketo
Acid Inhibitors Targeting the Cap-Snatching Endonuclease of
the Ebinur Lake Virus (Order: Bunyavirales)
Wenhua Kuang,a,b Huanyu Zhang,b Yan Cai,c,e Guilin Zhang,d
Fei Deng,b Hailong Li,d Yiwu Zhou,a Manli Wang,b
Peng Gong,f,g
Yu Guo,c
Zhihong Hub
aDepartment of... |
7EXA | Structure of mumps virus nucleoprotein without C-arm | ARTICLE
Structural plasticity of mumps virus nucleocapsids
with cryo-EM structures
Hong Shan1,2,7, Xin Su1,7, Tianhao Li1,7, Yuqi Qin1,7, Na Zhang1,3, Liuyan Yang4,5, Linsha Ma6, Yun Bai6, Lei Qi2,
Yunhui Liu1 & Qing-Tao Shen
1,2✉
Mumps virus (MuV) is a highly contagious human pathogen and frequently causes world-
wide... |
7EXB | DfgA-DfgB complex apo 2.4 angstrom | ARTICLE
C-Glycoside metabolism in the gut and in nature:
Identification, characterization, structural analyses
and distribution of C-C bond-cleaving enzymes
Takahiro Mori
1,2,3,8, Takuto Kumano
4,5,8, Haibing He1,8, Satomi Watanabe4,8, Miki Senda
6,
Toshio Moriya
6, Naruhiko Adachi
6, Sanae Hori4, Yuzu Terashita4, Masat... |
7EXD | Lasmiditan-bound serotonin 1F (5-HT1F) receptor-Gi protein complex | LETTER TO THE EDITOR
Structural basis for recognition of anti-migraine drug lasmiditan
by the serotonin receptor 5-HT1F–G protein complex
© CEMCS, CAS 2021
Cell Research (2021) 31:1036–1038; https://doi.org/10.1038/s41422-021-00527-4
Dear Editor,
The serotonin 5-HT1 receptor subtypes, including 5-HT1A, 5-HT1B,
5-HT1D, ... |
7EXF | Crystal structure of wild-type from Arabidopsis thaliana complexed with Galactose | research papers
154
https://doi.org/10.1107/S2059798323000037
Acta Cryst. (2023). D79, 154–167
Received 7 January 2022
Accepted 3 January 2023
Edited by G. Kurisu, Osaka University, Japan
Keywords: Arabidopsis thaliana; alkaline
-galactosidases; raffinose; RFO synthases;
transferase mechanism.
PDB references: AtAkGal... |
7EXG | Crystal structure of D383A mutant from Arabidopsis thaliana complexed with Galactose. | research papers
154
https://doi.org/10.1107/S2059798323000037
Acta Cryst. (2023). D79, 154–167
Received 7 January 2022
Accepted 3 January 2023
Edited by G. Kurisu, Osaka University, Japan
Keywords: Arabidopsis thaliana; alkaline
-galactosidases; raffinose; RFO synthases;
transferase mechanism.
PDB references: AtAkGal... |
7EXH | Crystal structure of D383A mutant from Arabidopsis thaliana complexed with Galactinol. | research papers
154
https://doi.org/10.1107/S2059798323000037
Acta Cryst. (2023). D79, 154–167
Received 7 January 2022
Accepted 3 January 2023
Edited by G. Kurisu, Osaka University, Japan
Keywords: Arabidopsis thaliana; alkaline
-galactosidases; raffinose; RFO synthases;
transferase mechanism.
PDB references: AtAkGal... |
7EXJ | Crystal structure of alkaline alpha-galctosidase D383A mutant from Arabidopsis thaliana complexed with Raffinose | research papers
154
https://doi.org/10.1107/S2059798323000037
Acta Cryst. (2023). D79, 154–167
Received 7 January 2022
Accepted 3 January 2023
Edited by G. Kurisu, Osaka University, Japan
Keywords: Arabidopsis thaliana; alkaline
-galactosidases; raffinose; RFO synthases;
transferase mechanism.
PDB references: AtAkGal... |
7EXM | The N-terminal crystal structure of SARS-CoV-2 NSP2 | RESEARCH ARTICLE
Structure and Function of N-Terminal Zinc Finger Domain
of SARS-CoV-2 NSP2
Jun Ma1 • Yiyun Chen2 • Wei Wu1 • Zhongzhou Chen1
Received: 14 June 2021 / Accepted: 15 July 2021 / Published online: 16 August 2021
Wuhan Institute of Virology, CAS 2021
Abstract
SARS-CoV-2 has become a global pandemic threat... |
7EXQ | Crystal structure of alkaline alpha-galactosidase D383A mutant from Arabidopsis thaliana complexed with product-galactose and sucrose. | research papers
154
https://doi.org/10.1107/S2059798323000037
Acta Cryst. (2023). D79, 154–167
Received 7 January 2022
Accepted 3 January 2023
Edited by G. Kurisu, Osaka University, Japan
Keywords: Arabidopsis thaliana; alkaline
-galactosidases; raffinose; RFO synthases;
transferase mechanism.
PDB references: AtAkGal... |
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