protein_name stringlengths 4 4 | structure_title stringlengths 3 322 | main_text stringlengths 0 302k |
|---|---|---|
7ZJH | TRPV2-C16+Pro-2 | Article
https://doi.org/10.1038/s41467-022-35163-y
Cannabinoid non-cannabidiol site
modulation of TRPV2 structure and function
Liying Zhang1,2,3,11, Charlotte Simonsen1,11, Lucie Zimova
4, Kaituo Wang
3,
Lavanya Moparthi
5,6, Rachelle Gaudet
7, Maria Ekoff8, Gunnar Nilsson
8,
Ute A. Hellmich
9,10, Viktorie Vlachova
4, ... |
7ZJI | Transient receptor potential cation channel subfamily V member 2,Enhanced green fluorescent protein | Article
https://doi.org/10.1038/s41467-022-35163-y
Cannabinoid non-cannabidiol site
modulation of TRPV2 structure and function
Liying Zhang1,2,3,11, Charlotte Simonsen1,11, Lucie Zimova
4, Kaituo Wang
3,
Lavanya Moparthi
5,6, Rachelle Gaudet
7, Maria Ekoff8, Gunnar Nilsson
8,
Ute A. Hellmich
9,10, Viktorie Vlachova
4, ... |
7ZJJ | CspZ (BbCRASP-2) from Borrelia burgdorferi strain B379 | PNAS 2023 Vol. 120 No. 27 e2301549120
https://doi.org/10.1073/pnas.2301549120 1 of 9
RESEARCH ARTICLE |
Significance
Changes to pathogens’ ability to
infect particular hosts (“host
tropism”) often dictate modern
infectious disease outbreaks. Lyme
disease bacteria present a suitable
model to study the molec... |
7ZJK | CspZ (BbCRASP-2) from Borrelia burgdorferi strain B408 | PNAS 2023 Vol. 120 No. 27 e2301549120
https://doi.org/10.1073/pnas.2301549120 1 of 9
RESEARCH ARTICLE |
Significance
Changes to pathogens’ ability to
infect particular hosts (“host
tropism”) often dictate modern
infectious disease outbreaks. Lyme
disease bacteria present a suitable
model to study the molec... |
7ZJM | Crystal structure of a complex between CspZ from Borrelia burgdorferi strain B408 and human FH SCR domains 6-7 | PNAS 2023 Vol. 120 No. 27 e2301549120
https://doi.org/10.1073/pnas.2301549120 1 of 9
RESEARCH ARTICLE |
Significance
Changes to pathogens’ ability to
infect particular hosts (“host
tropism”) often dictate modern
infectious disease outbreaks. Lyme
disease bacteria present a suitable
model to study the molec... |
7ZJS | Structural basis of centromeric cohesion protection by SGO1 | Nature Structural & Molecular Biology | Volume 30 | June 2023 | 853–859
853
nature structural & molecular biology
https://doi.org/10.1038/s41594-023-00968-y
Article
Structural basis of centromeric
cohesion protection
Alberto García-Nieto1,5, Amrita Patel2,5, Yan Li3,5, Roel Oldenkamp1,
Leonardo Feletto2, Joshua J. G... |
7ZJU | Structure of human USPL1 in covalent complex with SUMO3-2Br probe | Native Semisynthesis of Isopeptide-Linked Substrates for Specificity
Analysis of Deubiquitinases and Ubl Proteases
Zhou Zhao, Rachel O’Dea, Kim Wendrich, Nafizul Kazi, and Malte Gersch*
Cite This: J. Am. Chem. Soc. 2023, 145, 20801−20812
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Supporting Informat... |
7ZJV | Structure of human USPL1 in covalent complex with DeltaN-SUMO2/3-PA probe | Native Semisynthesis of Isopeptide-Linked Substrates for Specificity
Analysis of Deubiquitinases and Ubl Proteases
Zhou Zhao, Rachel O’Dea, Kim Wendrich, Nafizul Kazi, and Malte Gersch*
Cite This: J. Am. Chem. Soc. 2023, 145, 20801−20812
Read Online
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Metrics & More
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Supporting Informat... |
7ZJW | Rabbit 80S ribosome as it decodes the Sec-UGA codon | Structure of the mammalian ribosome as it decodes the
selenocysteine UGA codon
Tarek Hilal1,*,†, Benjamin Y. Killam2, Milica Grozdanović2,‡, Malgorzata Dobosz-
Bartoszek2,§, Justus Loerke1, Jörg Bürger1,3, Thorsten Mielke3, Paul R. Copeland4, Miljan
Simonović2,*,¶, Christian M. T. Spahn1,*
1Institut für Medizinische ... |
7ZJX | Rabbit 80S ribosome programmed with SECIS and SBP2 | Structure of the mammalian ribosome as it decodes the
selenocysteine UGA codon
Tarek Hilal1,*,†, Benjamin Y. Killam2, Milica Grozdanović2,‡, Malgorzata Dobosz-
Bartoszek2,§, Justus Loerke1, Jörg Bürger1,3, Thorsten Mielke3, Paul R. Copeland4, Miljan
Simonović2,*,¶, Christian M. T. Spahn1,*
1Institut für Medizinische ... |
7ZJY | The NMR structure of the MAX67 effector from Magnaporthe Oryzae | RESEARCH ARTICLE
The structural landscape and diversity of
Pyricularia oryzae MAX effectors revisited
Mounia LahfaID1, Philippe BartheID1, Karine de Guillen1, Stella CesariID2, Mouna Raji1,
Thomas KrojID2, Marie Le Naour—VernetID2, Franc¸ois HohID1, Pierre GladieuxID2,
Christian RoumestandID1, Je´roˆme GracyID1, Nathal... |
7ZK0 | The NMR structure of the MAX60 effector from Magnaporthe Oryzae | RESEARCH ARTICLE
The structural landscape and diversity of
Pyricularia oryzae MAX effectors revisited
Mounia LahfaID1, Philippe BartheID1, Karine de Guillen1, Stella CesariID2, Mouna Raji1,
Thomas KrojID2, Marie Le Naour—VernetID2, Franc¸ois HohID1, Pierre GladieuxID2,
Christian RoumestandID1, Je´roˆme GracyID1, Nathal... |
7ZK1 | Crystal structure of cystinosin from Arabidopsis thaliana bound to sybody and nanobody | nature communications
Article
https://doi.org/10.1038/s41467-022-32589-2
Structural basis for proton coupled cystine
transport by cystinosin
Mark Löbel
1, Sacha P. Salphati
1,2, Kamel El Omari
3, Armin Wagner
3,
Stephen J. Tucker
2,4, Joanne L. Parker
1
& Simon Newstead
1,4
Amino acid transporters play a key role contr... |
7ZK2 | Crystal Structure of human Brachyury G177D variant in complex with CSC027898502 | Article
https://doi.org/10.1038/s41467-025-56213-1
Structural insights into human brachyury
DNA recognition and discovery of
progressible binders for cancer therapy
Joseph A. Newman
1
, Angeline E. Gavard1,5, Nergis Imprachim
1,6,
Hazel Aitkenhead1,7, Hadley E. Sheppard2,8, Robert te Poele
2, Paul A. Clarke
2,
Mohammad... |
7ZK3 | Structure of 1PBC- and calcium-bound mTMEM16A(ac) chloride channel at 2.85 A resolution | ARTICLE
Inhibition mechanism of the chloride channel
TMEM16A by the pore blocker 1PBC
Andy K. M. Lam
1✉, Sonja Rutz
1 & Raimund Dutzler
1✉
TMEM16A, a calcium-activated chloride channel involved in multiple cellular processes, is a
proposed target for diseases such as hypertension, asthma, and cystic fibrosis. Despite th... |
7ZK4 | The ABCB1 L335C mutant (mABCB1) in the outward facing state | Gewering, Waghray et al. eLife 2023;12:RP90174. DOI: https://doi.org/10.7554/eLife.90174
1 of 21
Tracing the substrate translocation
mechanism in P-glycoprotein
Theresa Gewering1,2†, Deepali Waghray3†, Kristian Parey1,2,4, Hendrik Jung5,
Nghi NB Tran6, Joel Zapata6, Pengyi Zhao7, Hao Chen7, Dovile Januliene1,2,4, ... |
7ZK5 | ABCB1 L335C mutant (mABCB1) in the outward facing state bound to AAC | Gewering, Waghray et al. eLife 2023;12:RP90174. DOI: https://doi.org/10.7554/eLife.90174
1 of 21
Tracing the substrate translocation
mechanism in P-glycoprotein
Theresa Gewering1,2†, Deepali Waghray3†, Kristian Parey1,2,4, Hendrik Jung5,
Nghi NB Tran6, Joel Zapata6, Pengyi Zhao7, Hao Chen7, Dovile Januliene1,2,4, ... |
7ZK6 | ABCB1 L335C mutant (mABCB1) in the outward facing state bound to 2 molecules of AAC | Gewering, Waghray et al. eLife 2023;12:RP90174. DOI: https://doi.org/10.7554/eLife.90174
1 of 21
Tracing the substrate translocation
mechanism in P-glycoprotein
Theresa Gewering1,2†, Deepali Waghray3†, Kristian Parey1,2,4, Hendrik Jung5,
Nghi NB Tran6, Joel Zapata6, Pengyi Zhao7, Hao Chen7, Dovile Januliene1,2,4, ... |
7ZK8 | ABCB1 L971C mutant (mABCB1) in the outward facing state bound to AAC | Gewering, Waghray et al. eLife 2023;12:RP90174. DOI: https://doi.org/10.7554/eLife.90174
1 of 21
Tracing the substrate translocation
mechanism in P-glycoprotein
Theresa Gewering1,2†, Deepali Waghray3†, Kristian Parey1,2,4, Hendrik Jung5,
Nghi NB Tran6, Joel Zapata6, Pengyi Zhao7, Hao Chen7, Dovile Januliene1,2,4, ... |
7ZK9 | ABCB1 L971C mutant (mABCB1) in the inward facing state | Gewering, Waghray et al. eLife 2023;12:RP90174. DOI: https://doi.org/10.7554/eLife.90174
1 of 21
Tracing the substrate translocation
mechanism in P-glycoprotein
Theresa Gewering1,2†, Deepali Waghray3†, Kristian Parey1,2,4, Hendrik Jung5,
Nghi NB Tran6, Joel Zapata6, Pengyi Zhao7, Hao Chen7, Dovile Januliene1,2,4, ... |
7ZKA | ABCB1 V978C mutant (mABCB1) in the outward facing state bound to AAC | Gewering, Waghray et al. eLife 2023;12:RP90174. DOI: https://doi.org/10.7554/eLife.90174
1 of 21
Tracing the substrate translocation
mechanism in P-glycoprotein
Theresa Gewering1,2†, Deepali Waghray3†, Kristian Parey1,2,4, Hendrik Jung5,
Nghi NB Tran6, Joel Zapata6, Pengyi Zhao7, Hao Chen7, Dovile Januliene1,2,4, ... |
7ZKB | ABCB1 V978C mutant (mABCB1) in the inward facing state | Gewering, Waghray et al. eLife 2023;12:RP90174. DOI: https://doi.org/10.7554/eLife.90174
1 of 21
Tracing the substrate translocation
mechanism in P-glycoprotein
Theresa Gewering1,2†, Deepali Waghray3†, Kristian Parey1,2,4, Hendrik Jung5,
Nghi NB Tran6, Joel Zapata6, Pengyi Zhao7, Hao Chen7, Dovile Januliene1,2,4, ... |
7ZKC | Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum (apo form) | iScience
Article
A quinolin-8-ol sub-millimolar inhibitor of UGGT,
the ER glycoprotein folding quality control
checkpoint
Kevin P. Guay,
Roberta Ibba, J.L.
Kiappes, ..., Daniel
N. Hebert, Nicole
Zitzmann, Pietro
Roversi
cpmode@gmail.com (C.P.M.)
dhebert@biochem.umass.edu
(D.N.H.)
nicole.zitzmann@bioch.ox.ac.uk
(N.Z.)
p... |
7ZKD | The NMR structure of the MAX47 effector from Magnaporthe Oryzae | RESEARCH ARTICLE
The structural landscape and diversity of
Pyricularia oryzae MAX effectors revisited
Mounia LahfaID1, Philippe BartheID1, Karine de Guillen1, Stella CesariID2, Mouna Raji1,
Thomas KrojID2, Marie Le Naour—VernetID2, Franc¸ois HohID1, Pierre GladieuxID2,
Christian RoumestandID1, Je´roˆme GracyID1, Nathal... |
7ZKE | Mot1:TBP:DNA - pre-hydrolysis state | Structural basis for TBP displacement from TATA box DNA by
the Swi2/Snf2 ATPase Mot1
Stephan Woike1,2, Sebastian Eustermann#1,2,3, James Jung#1,2, Simon Josef Wenzl1,2, Götz
Hagemann1,2, Joseph Bartho1,2, Katja Lammens1,2, Agata Butryn1,2,4, Franz Herzog2,5,
Karl-Peter Hopfner1,2,*
1Department of Biochemistry, Ludwi... |
7ZKF | Crystal Structure of human Brachyury G177D variant in complex with CF-5-86 | Article
https://doi.org/10.1038/s41467-025-56213-1
Structural insights into human brachyury
DNA recognition and discovery of
progressible binders for cancer therapy
Joseph A. Newman
1
, Angeline E. Gavard1,5, Nergis Imprachim
1,6,
Hazel Aitkenhead1,7, Hadley E. Sheppard2,8, Robert te Poele
2, Paul A. Clarke
2,
Mohammad... |
7ZKI | Cryo-EM structure of aIF1A:aIF5B:Met-tRNAiMet complex from a Pyrococcus abyssi 30S initiation complex | 6532–6548
Nucleic Acids Research, 2022, Vol. 50, No. 11
Published online 13 June 2022
https://doi.org/10.1093/nar/gkac490
Role of aIF5B in archaeal translation initiation
Ramy Kazan1, Gabrielle Bourgeois1, Christine Lazennec-Schurdevin1, Eric Larquet2,
Yves Mechulam1,*, Pierre-Damien Coureux1,* and Emmanuelle Schmitt
1... |
7ZKL | X-ray structure of the complex between human alpha thrombin and a pseudo-cyclic thrombin binding aptamer (TBA-NNp/DDp) - Crystal form alpha | Original Article
A terminal functionalization strategy
reveals unusual binding abilities
of anti-thrombin anticoagulant aptamers
Romualdo Troisi,1 Claudia Riccardi,1 Kévan Pérez de Carvasal,2 Michael Smietana,2 François Morvan,2
Pompea Del Vecchio,1 Daniela Montesarchio,1 and Filomena Sica1
1Department of Chemical Scie... |
7ZKM | X-ray structure of the complex between human alpha thrombin and a pseudo-cyclic thrombin binding aptamer (TBA-NNp/DDp) - Crystal form beta | Original Article
A terminal functionalization strategy
reveals unusual binding abilities
of anti-thrombin anticoagulant aptamers
Romualdo Troisi,1 Claudia Riccardi,1 Kévan Pérez de Carvasal,2 Michael Smietana,2 François Morvan,2
Pompea Del Vecchio,1 Daniela Montesarchio,1 and Filomena Sica1
1Department of Chemical Scie... |
7ZKN | X-ray structure of the complex between human alpha thrombin and a pseudo-cyclic thrombin binding aptamer (TBA-NNp/DDp) - Crystal form gamma | Original Article
A terminal functionalization strategy
reveals unusual binding abilities
of anti-thrombin anticoagulant aptamers
Romualdo Troisi,1 Claudia Riccardi,1 Kévan Pérez de Carvasal,2 Michael Smietana,2 François Morvan,2
Pompea Del Vecchio,1 Daniela Montesarchio,1 and Filomena Sica1
1Department of Chemical Scie... |
7ZKO | X-ray structure of the complex between human alpha thrombin and a pseudo-cyclic thrombin binding aptamer (TBA-NNp/DDp) - Crystal form delta | Original Article
A terminal functionalization strategy
reveals unusual binding abilities
of anti-thrombin anticoagulant aptamers
Romualdo Troisi,1 Claudia Riccardi,1 Kévan Pérez de Carvasal,2 Michael Smietana,2 François Morvan,2
Pompea Del Vecchio,1 Daniela Montesarchio,1 and Filomena Sica1
1Department of Chemical Scie... |
7ZKP | Late assembly intermediate of the proximal proton pumping module of complex I with assembly factors NDUFAF1 and CIA84 | ST RUCTURAL BIOLOGY
Insights into complex I assembly: Function of NDUFAF1
and a link with cardiolipin remodeling
Jonathan Schiller1,2†, Eike Laube3†, Ilka Wittig4, Werner Kühlbrandt3, Janet Vonck3*,
Volker Zickermann1,2*
Respiratory complex I is a ~1-MDa proton pump in mitochondria. Its structure has been reveal... |
7ZKQ | Early Pp module assembly intermediate of complex I | ST RUCTURAL BIOLOGY
Insights into complex I assembly: Function of NDUFAF1
and a link with cardiolipin remodeling
Jonathan Schiller1,2†, Eike Laube3†, Ilka Wittig4, Werner Kühlbrandt3, Janet Vonck3*,
Volker Zickermann1,2*
Respiratory complex I is a ~1-MDa proton pump in mitochondria. Its structure has been reveal... |
7ZKR | Human GABARAP in complex with stapled peptide Pen3-ortho | Structure-Based Design of Stapled Peptides That Bind
GABARAP and Inhibit Autophagy
Hawley Brown,
Department of Chemistry, Tufts University, Medford, Massachusetts 02155, United States
Mia Chung,
Department of Chemistry, Tufts University, Medford, Massachusetts 02155, United States
Alina Üffing,
Institute of Biological... |
7ZKW | Crystal structure of cystinosin from Arabidopsis thaliana in complex with Cystine and sybody | nature communications
Article
https://doi.org/10.1038/s41467-022-32589-2
Structural basis for proton coupled cystine
transport by cystinosin
Mark Löbel
1, Sacha P. Salphati
1,2, Kamel El Omari
3, Armin Wagner
3,
Stephen J. Tucker
2,4, Joanne L. Parker
1
& Simon Newstead
1,4
Amino acid transporters play a key role contr... |
7ZKY | Amyloid fibril from human systemic AA amyloidosis (vascular variant) | Article
https://doi.org/10.1038/s41467-022-34636-4
Amyloid fibril structure from the vascular
variant of systemic AA amyloidosis
Sambhasan Banerjee
1, Julian Baur1, Christoph Daniel
2,
Peter Benedikt Pfeiffer1, Manuel Hitzenberger3, Lukas Kuhn1, Sebastian Wiese
4,
Johan Bijzet5, Christian Haupt1, Kerstin U. Amann2, Mart... |
7ZKZ | Crystal structure of cystinosin from Arabidopsis thaliana bound to two nanobodies | nature communications
Article
https://doi.org/10.1038/s41467-022-32589-2
Structural basis for proton coupled cystine
transport by cystinosin
Mark Löbel
1, Sacha P. Salphati
1,2, Kamel El Omari
3, Armin Wagner
3,
Stephen J. Tucker
2,4, Joanne L. Parker
1
& Simon Newstead
1,4
Amino acid transporters play a key role contr... |
7ZL1 | PTX3 Pentraxin Domain | PTX3 structure determination using a hybrid cryoelectron
microscopy and AlphaFold approach offers insights into ligand
binding and complement activation
Dylan P. Noonea, Douwe J. Dijkstrab, Teun T. van der Klugta
, Peter A. van Veelenc, Arnoud H. de Ruc, Paul J. Hensbergenc
, Leendert A. Trouwb, and
Thomas H. Sharpa,1
... |
7ZL2 | Crystal Structure of human Brachyury G177D variant in complex with Molpolrt-039-246-810 | Article
https://doi.org/10.1038/s41467-025-56213-1
Structural insights into human brachyury
DNA recognition and discovery of
progressible binders for cancer therapy
Joseph A. Newman
1
, Angeline E. Gavard1,5, Nergis Imprachim
1,6,
Hazel Aitkenhead1,7, Hadley E. Sheppard2,8, Robert te Poele
2, Paul A. Clarke
2,
Mohammad... |
7ZL3 | Signal peptide mimicry primes Sec61 for client-selective inhibition | Nature Chemical Biology | Volume 19 | September 2023 | 1054–1062
1054
nature chemical biology
Article
https://doi.org/10.1038/s41589-023-01326-1
Signal peptide mimicry primes Sec61 for
client-selective inhibition
Shahid Rehan1, Dale Tranter1, Phillip P. Sharp
2, Gregory B. Craven
2,
Eric Lowe3, Janet L. Anderl3... |
7ZL4 | Cryo-EM structure of archaic chaperone-usher Csu pilus of Acinetobacter baumannii | Nature | Vol 609 | 8 September 2022 | 335
Article
Archaic chaperone–usher pili self-secrete
into superelastic zigzag springs
Natalia Pakharukova1,9, Henri Malmi1,9, Minna Tuittila1, Tobias Dahlberg2, Debnath Ghosal3,7,
Yi-Wei Chang3,8, Si Lhyam Myint4, Sari Paavilainen1, Stefan David Knight5, Urpo Lamminmäki6, ... |
7ZL7 | Human GABARAP in complex with stapled peptide Pen8-ortho | Structure-Based Design of Stapled Peptides That Bind
GABARAP and Inhibit Autophagy
Hawley Brown,
Department of Chemistry, Tufts University, Medford, Massachusetts 02155, United States
Mia Chung,
Department of Chemistry, Tufts University, Medford, Massachusetts 02155, United States
Alina Üffing,
Institute of Biological... |
7ZL8 | NME1 in complex with succinyl-CoA | L IF E S CIEN CE S
Nucleoside diphosphate kinases 1 and 2 regulate a
protective liver response to a high-fat diet
Domenico Iuso1†, Isabel Garcia-Saez2, Yohann Couté3, Yoshiki Yamaryo-Botté1,
Elisabetta Boeri Erba2, Annie Adrait3, Nour Zeaiter4, Malgorzata Tokarska-Schlattner4,
Zuzana Macek Jilkova1,5, Fayçal Boussouar1... |
7ZL9 | Crystal structure of human GPCR Niacin receptor (HCA2) | Article
https://doi.org/10.1038/s41467-023-37177-6
Structural insights into the human niacin
receptor HCA2-Gi signalling complex
Yang Yang
1,2,3,9, Hye Jin Kang4,5,9, Ruogu Gao
2,3,9, Jingjing Wang1,
Gye Won Han6, Jeffrey F. DiBerto4, Lijie Wu1, Jiahui Tong1, Lu Qu1, Yiran Wu
1,
Ryan Pileski4,8, Xuemei Li2,3, Xuejun Ca... |
7ZLA | Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the half-closed conformation | Published online 28 June 2023
Nucleic Acids Research, 2023, Vol. 51, No. 15 8237–8254
https://doi.org/10.1093/nar/gkad552
Structural insights into the DNA recognition
mechanism by the bacterial transcription factor PdxR
Ida Freda 1 , † , C ´ecile Exertier 2 , † , Anna Barile 2 , Antonio Chaves-Sanjuan 3 ,
Mirella... |
7ZLG | Cryo-EM structure of C-mannosyltransferase CeDPY19, in complex with acceptor peptide and bound to CMT2-Fab and anti-Fab nanobody | Nature Chemical Biology | Volume 19 | May 2023 | 575–584
575
nature chemical biology
https://doi.org/10.1038/s41589-022-01219-9
Article
Structure, sequon recognition
and mechanism of tryptophan
C-mannosyltransferase
Joël S. Bloch
1,7, Alan John
2,3, Runyu Mao
2,3, Somnath Mukherjee4,
Jérémy Boilevin5, Rossi... |
7ZLH | Cryo-EM structure of C-mannosyltransferase CeDPY19, in apo state, bound to CMT2-Fab and anti-Fab nanobody | Nature Chemical Biology | Volume 19 | May 2023 | 575–584
575
nature chemical biology
https://doi.org/10.1038/s41589-022-01219-9
Article
Structure, sequon recognition
and mechanism of tryptophan
C-mannosyltransferase
Joël S. Bloch
1,7, Alan John
2,3, Runyu Mao
2,3, Somnath Mukherjee4,
Jérémy Boilevin5, Rossi... |
7ZLI | Cryo-EM structure of C-mannosyltransferase CeDPY19, in complex with Dol25-P-Man and bound to CMT2-Fab and anti-Fab nanobody | Nature Chemical Biology | Volume 19 | May 2023 | 575–584
575
nature chemical biology
https://doi.org/10.1038/s41589-022-01219-9
Article
Structure, sequon recognition
and mechanism of tryptophan
C-mannosyltransferase
Joël S. Bloch
1,7, Alan John
2,3, Runyu Mao
2,3, Somnath Mukherjee4,
Jérémy Boilevin5, Rossi... |
7ZLJ | Cryo-EM structure of C-mannosyltransferase CeDPY19, in ternary complex with Dol25-P-C-Man and acceptor peptide, bound to CMT2-Fab and anti-Fab nanobody | Nature Chemical Biology | Volume 19 | May 2023 | 575–584
575
nature chemical biology
https://doi.org/10.1038/s41589-022-01219-9
Article
Structure, sequon recognition
and mechanism of tryptophan
C-mannosyltransferase
Joël S. Bloch
1,7, Alan John
2,3, Runyu Mao
2,3, Somnath Mukherjee4,
Jérémy Boilevin5, Rossi... |
7ZLK | AMC009 SOSIPv5.2 in complex with Fabs ACS114 and ACS122 | RESEARCH ARTICLE
Complementary antibody lineages achieve
neutralization breadth in an HIV-1 infected
elite neutralizer
Jelle van SchootenID1, Anna Schorcht1, Elinaz Farokhi2, Jeffrey C. Umotoy1,
Hongmei Gao3, Tom L. G. M. van den Kerkhof1,4, Jessica Dorning5, Tim G. Rijkhold
Meesters1, Patricia van der Woude1, Judith A... |
7ZLL | Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with the 5-[(morpholin-4-yl)methyl]quinolin-8-ol inhibitor | iScience
Article
A quinolin-8-ol sub-millimolar inhibitor of UGGT,
the ER glycoprotein folding quality control
checkpoint
Kevin P. Guay,
Roberta Ibba, J.L.
Kiappes, ..., Daniel
N. Hebert, Nicole
Zitzmann, Pietro
Roversi
cpmode@gmail.com (C.P.M.)
dhebert@biochem.umass.edu
(D.N.H.)
nicole.zitzmann@bioch.ox.ac.uk
(N.Z.)
p... |
7ZLM | Crystal structure of SOCS2:ElonginB:ElonginC in complex with compound MN551 | Article
https://doi.org/10.1038/s41467-023-41894-3
Structure-based design of a
phosphotyrosine-masked covalent
ligand targeting the E3 ligase SOCS2
Sarath Ramachandran
1,4, Nikolai Makukhin1,3,4, Kevin Haubrich
1,
Manjula Nagala1, Beth Forrester1, Dylan M. Lynch1, Ryan Casement1,
Andrea Testa1,3, Elvira Bruno1, Rosaria... |
7ZLN | Crystal structure of SOCS2:ElonginB:ElonginC in complex with compound 11 | Article
https://doi.org/10.1038/s41467-023-41894-3
Structure-based design of a
phosphotyrosine-masked covalent
ligand targeting the E3 ligase SOCS2
Sarath Ramachandran
1,4, Nikolai Makukhin1,3,4, Kevin Haubrich
1,
Manjula Nagala1, Beth Forrester1, Dylan M. Lynch1, Ryan Casement1,
Andrea Testa1,3, Elvira Bruno1, Rosaria... |
7ZLO | Crystal structure of SOCS2:ElonginB:ElonginC in complex with compound 12 | Article
https://doi.org/10.1038/s41467-023-41894-3
Structure-based design of a
phosphotyrosine-masked covalent
ligand targeting the E3 ligase SOCS2
Sarath Ramachandran
1,4, Nikolai Makukhin1,3,4, Kevin Haubrich
1,
Manjula Nagala1, Beth Forrester1, Dylan M. Lynch1, Ryan Casement1,
Andrea Testa1,3, Elvira Bruno1, Rosaria... |
7ZLP | Crystal structure of SOCS2:ElonginB:ElonginC in complex with compound 9 | Article
https://doi.org/10.1038/s41467-023-41894-3
Structure-based design of a
phosphotyrosine-masked covalent
ligand targeting the E3 ligase SOCS2
Sarath Ramachandran
1,4, Nikolai Makukhin1,3,4, Kevin Haubrich
1,
Manjula Nagala1, Beth Forrester1, Dylan M. Lynch1, Ryan Casement1,
Andrea Testa1,3, Elvira Bruno1, Rosaria... |
7ZLR | Crystal structure of SOCS2:ElonginB:ElonginC in complex with compound 13 | Article
https://doi.org/10.1038/s41467-023-41894-3
Structure-based design of a
phosphotyrosine-masked covalent
ligand targeting the E3 ligase SOCS2
Sarath Ramachandran
1,4, Nikolai Makukhin1,3,4, Kevin Haubrich
1,
Manjula Nagala1, Beth Forrester1, Dylan M. Lynch1, Ryan Casement1,
Andrea Testa1,3, Elvira Bruno1, Rosaria... |
7ZLS | co-crystal structure of SOCS2:ElonginB:ElonginC in complex with compound 13 | Article
https://doi.org/10.1038/s41467-023-41894-3
Structure-based design of a
phosphotyrosine-masked covalent
ligand targeting the E3 ligase SOCS2
Sarath Ramachandran
1,4, Nikolai Makukhin1,3,4, Kevin Haubrich
1,
Manjula Nagala1, Beth Forrester1, Dylan M. Lynch1, Ryan Casement1,
Andrea Testa1,3, Elvira Bruno1, Rosaria... |
7ZLU | Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP-2-deoxy-2-fluoro-D-glucose | iScience
Article
A quinolin-8-ol sub-millimolar inhibitor of UGGT,
the ER glycoprotein folding quality control
checkpoint
Kevin P. Guay,
Roberta Ibba, J.L.
Kiappes, ..., Daniel
N. Hebert, Nicole
Zitzmann, Pietro
Roversi
cpmode@gmail.com (C.P.M.)
dhebert@biochem.umass.edu
(D.N.H.)
nicole.zitzmann@bioch.ox.ac.uk
(N.Z.)
p... |
7ZLV | Tail tip of siphophage T5 : central fibre protein pb4 | ST RUCTURAL BIOLOGY
Structural basis of bacteriophage T5 infection trigger
and E. coli cell wall perforation
Romain Linares, Charles-Adrien Arnaud, Grégory Effantin, Claudine Darnault,
Nathan Hugo Epalle, Elisabetta Boeri Erba, Guy Schoehn, Cécile Breyton*
Most bacteriophages present a tail allowing host recognition, c... |
7ZLW | NME1 in complex with ADP | L IF E S CIEN CE S
Nucleoside diphosphate kinases 1 and 2 regulate a
protective liver response to a high-fat diet
Domenico Iuso1†, Isabel Garcia-Saez2, Yohann Couté3, Yoshiki Yamaryo-Botté1,
Elisabetta Boeri Erba2, Annie Adrait3, Nour Zeaiter4, Malgorzata Tokarska-Schlattner4,
Zuzana Macek Jilkova1,5, Fayçal Boussouar1... |
7ZLY | Crystal structure of human GPCR Niacin receptor (HCA2) expressed from Spodoptera frugiperda | Article
https://doi.org/10.1038/s41467-023-37177-6
Structural insights into the human niacin
receptor HCA2-Gi signalling complex
Yang Yang
1,2,3,9, Hye Jin Kang4,5,9, Ruogu Gao
2,3,9, Jingjing Wang1,
Gye Won Han6, Jeffrey F. DiBerto4, Lijie Wu1, Jiahui Tong1, Lu Qu1, Yiran Wu
1,
Ryan Pileski4,8, Xuemei Li2,3, Xuejun Ca... |
7ZLZ | Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor | Structure Based Discovery of Inhibitors of CYP125 and
CYP142 from Mycobacterium tuberculosis
Mona M. Katariya+,[b] Matthew Snee+,[c] Richard B. Tunnicliffe,[c] Madeline E. Kavanagh,[b, d]
Helena I. M. Boshoff,[e] Cecilia N. Amadi,[c] Colin W. Levy,[c] Andrew W. Munro,[c] Chris Abell,[b]
David Leys,[c] Anthony G. Coyne,... |
7ZM0 | Structure of UCHL1 in complex with GK13S inhibitor | Article
https://doi.org/10.1038/s41467-022-33559-4
Structural basis for specific inhibition of the
deubiquitinase UCHL1
Christian Grethe
1,2,4, Mirko Schmidt
1,2,4, Gian-Marvin Kipka1,2,
Rachel O’Dea1,2, Kai Gallant1,2, Petra Janning3 & Malte Gersch
1,2
Ubiquitination regulates protein homeostasis and is tightly control... |
7ZM5 | Structure of Mossman virus receptor binding protein | | Structural Biology | Research Article
Crystal structure and solution state of the C-terminal head
region of the narmovirus receptor binding protein
Alice J. Stelfox,1,2 Kasopefoluwa Y. Oguntuyo,3 Ilona Rissanen,1,4 Karl Harlos,1 Robert Rambo,5 Benhur Lee,3 Thomas A. Bowden1
AUTHOR AFFILIATIONS See affiliation list ... |
7ZM6 | Nariva virus receptor binding protein | | Structural Biology | Research Article
Crystal structure and solution state of the C-terminal head
region of the narmovirus receptor binding protein
Alice J. Stelfox,1,2 Kasopefoluwa Y. Oguntuyo,3 Ilona Rissanen,1,4 Karl Harlos,1 Robert Rambo,5 Benhur Lee,3 Thomas A. Bowden1
AUTHOR AFFILIATIONS See affiliation list ... |
7ZM7 | CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (inhibited by DDM) | Laube et al., Sci. Adv. 8, eadc9952 (2022) 25 November 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 14
ST RUCTURAL B IOL OG Y
Conformational changes in mitochondrial
complex I of the thermophilic eukaryote
Chaetomium thermophilum
Eike Laube1*, Jakob Meier-Credo1,2, Julian D. Langer1,2, Werner Kühl... |
7ZM8 | CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (inhibited by DDM) - membrane arm | Laube et al., Sci. Adv. 8, eadc9952 (2022) 25 November 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 14
ST RUCTURAL B IOL OG Y
Conformational changes in mitochondrial
complex I of the thermophilic eukaryote
Chaetomium thermophilum
Eike Laube1*, Jakob Meier-Credo1,2, Julian D. Langer1,2, Werner Kühl... |
7ZM9 | Ketosynthase domain 3 of Brevibacillus Brevis orphan BGC11 | Tittes et al., Sci. Adv. 8, eabo6918 (2022) 21 September 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 9
ST RUCTURAL B IOL OG Y
The structure of a polyketide synthase bimodule core
Yves U. Tittes, Dominik A. Herbst†, Solène F. X. Martin, Hugo Munoz-Hernandez,
Roman P. Jakob, Timm Maier*
Polyketide syn... |
7ZMA | Ketosynthase domain of module 4 from Brevibacillus Brevis orphan BGC11 | Tittes et al., Sci. Adv. 8, eabo6918 (2022) 21 September 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 9
ST RUCTURAL B IOL OG Y
The structure of a polyketide synthase bimodule core
Yves U. Tittes, Dominik A. Herbst†, Solène F. X. Martin, Hugo Munoz-Hernandez,
Roman P. Jakob, Timm Maier*
Polyketide syn... |
7ZMB | CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 2) | Laube et al., Sci. Adv. 8, eadc9952 (2022) 25 November 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 14
ST RUCTURAL B IOL OG Y
Conformational changes in mitochondrial
complex I of the thermophilic eukaryote
Chaetomium thermophilum
Eike Laube1*, Jakob Meier-Credo1,2, Julian D. Langer1,2, Werner Kühl... |
7ZMC | Ketosynthase domain of module 4 from Brevibacillus Brevis orphan BGC11 | Tittes et al., Sci. Adv. 8, eabo6918 (2022) 21 September 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 9
ST RUCTURAL B IOL OG Y
The structure of a polyketide synthase bimodule core
Yves U. Tittes, Dominik A. Herbst†, Solène F. X. Martin, Hugo Munoz-Hernandez,
Roman P. Jakob, Timm Maier*
Polyketide syn... |
7ZMD | Ketosynthase domain of module 3 from Brevibacillus Brevis orphan BGC11 | Tittes et al., Sci. Adv. 8, eabo6918 (2022) 21 September 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 9
ST RUCTURAL B IOL OG Y
The structure of a polyketide synthase bimodule core
Yves U. Tittes, Dominik A. Herbst†, Solène F. X. Martin, Hugo Munoz-Hernandez,
Roman P. Jakob, Timm Maier*
Polyketide syn... |
7ZME | CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 2) - membrane arm | Laube et al., Sci. Adv. 8, eadc9952 (2022) 25 November 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 14
ST RUCTURAL B IOL OG Y
Conformational changes in mitochondrial
complex I of the thermophilic eukaryote
Chaetomium thermophilum
Eike Laube1*, Jakob Meier-Credo1,2, Julian D. Langer1,2, Werner Kühl... |
7ZMF | Dehydratase domain of module 3 from Brevibacillus Brevis orphan BGC11 | Tittes et al., Sci. Adv. 8, eabo6918 (2022) 21 September 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 9
ST RUCTURAL B IOL OG Y
The structure of a polyketide synthase bimodule core
Yves U. Tittes, Dominik A. Herbst†, Solène F. X. Martin, Hugo Munoz-Hernandez,
Roman P. Jakob, Timm Maier*
Polyketide syn... |
7ZMG | CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 1) | Laube et al., Sci. Adv. 8, eadc9952 (2022) 25 November 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 14
ST RUCTURAL B IOL OG Y
Conformational changes in mitochondrial
complex I of the thermophilic eukaryote
Chaetomium thermophilum
Eike Laube1*, Jakob Meier-Credo1,2, Julian D. Langer1,2, Werner Kühl... |
7ZMH | CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 1) - membrane arm | Laube et al., Sci. Adv. 8, eadc9952 (2022) 25 November 2022
SCIE N C E A D V A NCES | RESEA R CH A RT ICL E
1 of 14
ST RUCTURAL B IOL OG Y
Conformational changes in mitochondrial
complex I of the thermophilic eukaryote
Chaetomium thermophilum
Eike Laube1*, Jakob Meier-Credo1,2, Julian D. Langer1,2, Werner Kühl... |
7ZMJ | SFX structure of dye-type peroxidase DtpB R243A variant in the ferric state | Serial Femtosecond Crystallography Reveals the Role of Water in
the One- or Two-Electron Redox Chemistry of Compound I in the
Catalytic Cycle of the B‑Type Dye-Decolorizing Peroxidase DtpB
Marina Lučić, Michael T. Wilson, Takehiko Tosha, Hiroshi Sugimoto, Anastasya Shilova, Danny Axford,
Robin L. Owen, Michael A. Hou... |
7ZMK | Structure of human MFAP4 in complex with the Fab fragment of the AS0326 monoclonal antibody | Original Article
Pharmacological blocking
of microfibrillar-associated protein 4 reduces
retinal neoangiogenesis and vascular leakage
Anders Schlosser,1 Bartosz Pilecki,1 Claire Allen,2 Andrew V. Benest,2 Amy P. Lynch,2 Jing Hua,2 Nikita Ved,2
Zoe Blackley,2 Thomas L. Andersen,3,4,5 Dorle Hennig,1 Jonas H. Graversen,1 S... |
7ZMU | 14-3-3s binding to non-natural peptide 2d | Functional mapping of the 14-3-3 hub protein as
a guide to design 14-3-3 molecular glues†
Bente A. Somsen,
Fenna W. B. Craenmehr,
Wei-Hong W. Liu, Auke A. Koops,
Marloes A. M. Pennings,
Emira J. Visser,
Christian Ottmann,
Peter J. Cossar
* and Luc Brunsveld
*
Molecular glues represent an evolution in drug discovery, ho... |
7ZMW | 14-3-3s binding to non-natural peptide 2c | Functional mapping of the 14-3-3 hub protein as
a guide to design 14-3-3 molecular glues†
Bente A. Somsen,
Fenna W. B. Craenmehr,
Wei-Hong W. Liu, Auke A. Koops,
Marloes A. M. Pennings,
Emira J. Visser,
Christian Ottmann,
Peter J. Cossar
* and Luc Brunsveld
*
Molecular glues represent an evolution in drug discovery, ho... |
7ZN2 | Tail tip of siphophage T5 : full complex after interaction with its bacterial receptor FhuA | ST RUCTURAL BIOLOGY
Structural basis of bacteriophage T5 infection trigger
and E. coli cell wall perforation
Romain Linares, Charles-Adrien Arnaud, Grégory Effantin, Claudine Darnault,
Nathan Hugo Epalle, Elisabetta Boeri Erba, Guy Schoehn, Cécile Breyton*
Most bacteriophages present a tail allowing host recognition, c... |
7ZN4 | Tail tip of siphophage T5 : bent fibre after interaction with its bacterial receptor FhuA | ST RUCTURAL BIOLOGY
Structural basis of bacteriophage T5 infection trigger
and E. coli cell wall perforation
Romain Linares, Charles-Adrien Arnaud, Grégory Effantin, Claudine Darnault,
Nathan Hugo Epalle, Elisabetta Boeri Erba, Guy Schoehn, Cécile Breyton*
Most bacteriophages present a tail allowing host recognition, c... |
7ZN5 | Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the closed conformation, C2 symmetry. | Published online 28 June 2023
Nucleic Acids Research, 2023, Vol. 51, No. 15 8237–8254
https://doi.org/10.1093/nar/gkad552
Structural insights into the DNA recognition
mechanism by the bacterial transcription factor PdxR
Ida Freda 1 , † , C ´ecile Exertier 2 , † , Anna Barile 2 , Antonio Chaves-Sanjuan 3 ,
Mirella... |
7ZN6 | Crystal structure of laccase-like multicopper oxidase (LMCO) from Thermothelomyces thermophilus | research papers
Acta Cryst. (2023). D79, 641–654
https://doi.org/10.1107/S2059798323004175
641
Received 3 March 2023
Accepted 12 May 2023
Edited by M. Czjzek, Station Biologique de
Roscoff, France
Keywords: laccase-like multicopper oxidases;
LMCOs; biocatalysts; crystal structure;
Thermothelomyces thermophila; molecula... |
7ZN7 | Cryo-EM structure of RCMV-E E27 bound to human DDB1 (deltaBPB) and rat STAT2 CCD | Article
Structural mechanism of CRL4-instructed
STAT2 degradation via a novel cytomegaloviral
DCAF receptor
Vu Thuy Khanh Le-Trilling1,†
, Sofia Banchenko2,†
, Darius Paydar1,3, Pia Madeleine Leipe1,
Lukas Binting2, Simon Lauer2
, Andrea Graziadei4
, Robin Klingen1
, Christine Gotthold2,
Jörg B€urger2,5
, Thilo Bracht6... |
7ZNJ | Structure of an ALYREF-exon junction complex hexamer | mRNA recognition and packaging by the human transcription-
export complex
Belén Pacheco-Fiallos#1,2, Matthias K. Vorländer#1, Daria Riabov-Bassat1, Laura Fin1,
Francis J. O’Reilly3, Farja I. Ayala1,2, Ulla Schellhaas1,2, Juri Rappsilber3,4, Clemens
Plaschka1,*
1Research Institute of Molecular Pathology (IMP), Vienna ... |
7ZNK | Structure of an endogenous human TREX complex bound to mRNA | mRNA recognition and packaging by the human transcription-
export complex
Belén Pacheco-Fiallos#1,2, Matthias K. Vorländer#1, Daria Riabov-Bassat1, Laura Fin1,
Francis J. O’Reilly3, Farja I. Ayala1,2, Ulla Schellhaas1,2, Juri Rappsilber3,4, Clemens
Plaschka1,*
1Research Institute of Molecular Pathology (IMP), Vienna ... |
7ZNL | Structure of the human TREX core THO-UAP56 complex | mRNA recognition and packaging by the human transcription-
export complex
Belén Pacheco-Fiallos#1,2, Matthias K. Vorländer#1, Daria Riabov-Bassat1, Laura Fin1,
Francis J. O’Reilly3, Farja I. Ayala1,2, Ulla Schellhaas1,2, Juri Rappsilber3,4, Clemens
Plaschka1,*
1Research Institute of Molecular Pathology (IMP), Vienna ... |
7ZNM | Artificial Unspecific Peroxygenase expressed in Pichia pastoris at 2.01 Angstrom resolution | Comparing the Catalytic and Structural Characteristics of
a ‘Short’ Unspecific Peroxygenase (UPO) Expressed in
Pichia pastoris and Escherichia coli
Wendy X. Q. Robinson,[a] Tamara Mielke,[a] Benjamin Melling,[a] Anibal Cuetos,[a]
Alison Parkin,[a] William P. Unsworth,[a] Jared Cartwright,[b] and Gideon Grogan*[a]
Unspe... |
7ZNN | Cryo-EM structure of RCMV-E E27 bound to human DDB1 (deltaBPB) and full-length rat STAT2 | Article
Structural mechanism of CRL4-instructed
STAT2 degradation via a novel cytomegaloviral
DCAF receptor
Vu Thuy Khanh Le-Trilling1,†
, Sofia Banchenko2,†
, Darius Paydar1,3, Pia Madeleine Leipe1,
Lukas Binting2, Simon Lauer2
, Andrea Graziadei4
, Robin Klingen1
, Christine Gotthold2,
Jörg B€urger2,5
, Thilo Bracht6... |
7ZNO | Crystal Structure of Unlinked NS2B_NS3 Protease from Zika Virus in Complex with Boronate Inhibitor MI-2270 | Boroleucine-Derived Covalent Inhibitors of the ZIKV
Protease
Niklas J. Braun+,[a] Simon Huber+,[a] Luna C. Schmacke,[a] Andreas Heine,[a] and
Torsten Steinmetzer*[a]
The Zika virus (ZIKV) remains a potential threat to the public
health due to the lack of both an approved vaccination or a
specific treatment. In this wor... |
7ZNT | CRYSTAL STRUCTURE OF AT7 IN COMPLEX WITH THE SECOND BROMODOMAIN OF HUMAN BRD4 AND PVHL:ELONGINC:ELONGINB | Functional E3 ligase hotspots and resistance mechanisms to
small-molecule degraders
Alexander Hanzl1, Ryan Casement#2, Hana Imrichova#1, Scott J. Hughes2,3, Eleonora
Barone1, Andrea Testa2,3, Sophie Bauer1,4, Jane Wright2, Matthias Brand1,4, Alessio Ciulli2,
✉, Georg E. Winter1,✉
1CeMM Research Center for Molecular M... |
7ZNV | Artificial Unspecific Peroxygenase expressed in Pichia pastoris at 1.21 Angstrom resolution | Comparing the Catalytic and Structural Characteristics of
a ‘Short’ Unspecific Peroxygenase (UPO) Expressed in
Pichia pastoris and Escherichia coli
Wendy X. Q. Robinson,[a] Tamara Mielke,[a] Benjamin Melling,[a] Anibal Cuetos,[a]
Alison Parkin,[a] William P. Unsworth,[a] Jared Cartwright,[b] and Gideon Grogan*[a]
Unspe... |
7ZNW | Artificial Unspecific Peroxygenase expressed in Escherichia coli at 2.09 Angstrom resolution | Comparing the Catalytic and Structural Characteristics of
a ‘Short’ Unspecific Peroxygenase (UPO) Expressed in
Pichia pastoris and Escherichia coli
Wendy X. Q. Robinson,[a] Tamara Mielke,[a] Benjamin Melling,[a] Anibal Cuetos,[a]
Alison Parkin,[a] William P. Unsworth,[a] Jared Cartwright,[b] and Gideon Grogan*[a]
Unspe... |
7ZNX | Crystal structure of cocaprin 1, inhibitor of cysteine and aspartic proteases from Coprinopsis cinerea | Citation: Renko, M.; Zupan, T.; Plaza,
D.F.; Schmieder, S.S.; Periši´c Nanut,
M.; Kos, J.; Turk, D.; Künzler, M.;
Sabotiˇc, J. Cocaprins, β-Trefoil Fold
Inhibitors of Cysteine and Aspartic
Proteases from Coprinopsis cinerea. Int.
J. Mol. Sci. 2022, 23, 4916. https://
doi.org/10.3390/ijms23094916
Academic Editors: Claud... |
7ZNY | Cryo-EM structure of the canine distemper virus tetrameric attachment glycoprotein | PNAS 2023 Vol. 120 No. 6 e2208866120
https://doi.org/10.1073/pnas.2208866120 1 of 7
RESEARCH ARTICLE |
Significance
Canine distemper virus (CDV) is
an enveloped RNA morbillivirus
related to the human pathogen
measles virus. CDV induces
severe outbreaks in wild and
endangered animals as well as in
domestic... |
7ZNZ | Crystal structure of unliganded form of FucOB, a GH95 family alpha-1,2-fucosidase from Akkermansia muciniphila | Article
https://doi.org/10.1038/s41467-023-37324-z
Turning universal O into rare Bombay
type blood
Itxaso Anso
1,2,8, Andreas Naegeli3,8, Javier O. Cifuente
1,2,8, Ane Orrantia4,
Erica Andersson3, Olatz Zenarruzabeitia4, Alicia Moraleda-Montoya1,
Mikel García-Alija1,2, Francisco Corzana
5, Rafael A. Del Orbe
6,
Francis... |
7ZO0 | Crystal structure of catalytic inactive unliganded form of FucOB, a GH95 family alpha-1,2-fucosidase from Akkermansia muciniphila | Article
https://doi.org/10.1038/s41467-023-37324-z
Turning universal O into rare Bombay
type blood
Itxaso Anso
1,2,8, Andreas Naegeli3,8, Javier O. Cifuente
1,2,8, Ane Orrantia4,
Erica Andersson3, Olatz Zenarruzabeitia4, Alicia Moraleda-Montoya1,
Mikel García-Alija1,2, Francisco Corzana
5, Rafael A. Del Orbe
6,
Francis... |
7ZO1 | SpCas9 bound to CD34 off-target9 DNA substrate | Structural basis for Cas9 off-target activity
Martin Pacesa1, Chun-Han Lin2,3, Antoine Cléry4, Aakash Saha5, Pablo R. Arantes5, Katja
Bargsten1,6, Matthew J. Irby2,7, Frédéric H.T. Allain4, Giulia Palermo5, Peter Cameron2,8,
Paul D. Donohoue2, Martin Jinek1,9
1Department of Biochemistry, University of Zurich, Wintert... |
7ZO2 | L1 metallo-beta-lactamase complex with hydrolysed doripenem | Interactions of hydrolyzed β-lactams with the L1 metallo-β-
lactamase: Crystallography supports stereoselective binding
of cephem/carbapenem products
Received for publication, October 5, 2022, and in revised form, February 25, 2023 Published, Papers in Press, March 15, 2023,
https://doi.org/10.1016/j.jbc.2023.104606
Ph... |
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