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[ [ "neuroendocrine tumors ( nets ) comprise a heterogeneous group of neoplasms that are frequently metastatic at the time of diagnosis , and distance of metastatic disease is , next to grading , one of the most important prognostic factors ( 1)(3 ) .", "the availability of modern imaging methods for diagnosi...	neuroendocrine tumors are a heterogeneous group of malignancies that present a diagnostic challenge . the majority of patients ( more than 60% ) present with metastatic disease at diagnosis . the diagnosis is based on histopathology , imaging , and circulating biomarkers . the histopathology should contain specific neu...
[ [ "members of the burkholderia cepacia complex ( bcc ) are gram - negative bacteria of the -proteobacteria subdivision and include plant , animal , and human pathogens , with a widespread distribution in natural and man - made inhabitats .", "have attracted significant commercial interest as biocontrol , bi...	the burkholderia cepacia complex ( bcc ) comprises at least 17 closely - related species of the -proteobacteria subdivision , widely distributed in natural and man - made inhabitats . bcc bacteria are endowed with an extraordinary metabolic diversity and emerged in the 1980s as life - threatening and difficult - to - t...
[ [ "a 36-year - old man presented with sudden severe occipital headache , and neck stiffness in may 1999 . after several weeks , the headache subsided , however , blurred vision subsequently developed .", "t1-weighted ( 665/14/2 [ repetition time / echo time / excitation ] ) and t2-weighted ( 4200/99/2 ) mr ...	herein , we report on an unusual case of craniopharyngioma arising in the temporal lobe with no prior history of surgery and with no connection to the craniopharyngeal duct . mr images showed a cystic tumor with a small solid portion . to the best of our knowledge , this is the first case of a craniopharyngioma occurri...
[ [ "a 22-year - old female reported with complaints of multiple missing teeth in upper and lower anterior region .", "the panoramic radiograph confirmed presence of retained primary teeth in both the arches . with the above findings and orthopantomogram ( opg ) figure , we came to a conclusion and diagnosed ...	ectodermal dysplasia represents a group of rare inherited conditions in which two or more ectodermally derived anatomical structures fail to develop . early dental intervention can improve patients appearance , thereby minimizing associated emotional and psychological problems in these patients . treatment requires a t...
[ [ ", we examined the effects and severity of \n pandemic h1n1 \n influenza during the 2009 influenza season , in patients with cancer and sct in two cities of argentina .", "the first cases of pandemic \n influenza a ( h1n1 ) in argentina were reported in may 2009 , in travelers returning from mexico and th...	background : during march 2009 a novel influenza a virus emerged in mexico . we describe the clinical picture of the pandemic influenza a ( h1n1 ) influenza in cancer patients during the 2009 influenza season . methods : twelve centers participated in a multicenter retrospective observational study of cancer patien...
[ [ "here , we analyze early patterns of hcv sequence diversity in epidemiologically linked , viral sequence confirmed , donor - recipient , acute - to - acute transmission pairs , including human - to - human and human - to - chimpanzee infections .", "our results illustrate how t / f analysis in hcv infecti...	abstractdespite the recent development of highly effective anti - hepatitis c virus ( hcv ) drugs , the global burden of this pathogen remains immense . control or eradication of hcv will likely require the broad application of antiviral drugs and development of an effective vaccine . a precise molecular identification...
[ [ ", we studied the acute effects of exenatide , a short - acting glp-1 analog , on glucose tolerance to a mixed - meal tolerance test ( mmtt ) and an intravenous glucose tolerance test ( ivgtt ) .", "we analyzed insulin secretion rates ( isrs ) , gastric emptying , and hormonal responses including glucagon...	objectiveglucagon - like peptide 1 ( glp-1 ) is an incretin hormone that is released from the gastrointestinal tract . treatment with glp-1 analogs has proven to be of clinical use for patients with type 2 diabetes . patients with type 1 diabetes , particularly those with residual -cell function , may also respond to t...
[ [ "this intermediate interacts with appropriate trna molecule , and amino acid is transferred to 3 end of the trna .", "there are 20 distinct aminoacyl - trnas , with each one of them being responsible for aminoacylating its cognate trna with unique amino acid in a two - step catalytic reaction .", "thi...	arginine residues are very important for the structure of proteins and their action . arginine is essential for many natural processes because it has unique ionizable group under physiological conditions . numerous mimetics of arginine were synthesized and their biological effects were evaluated , but the mechanisms of...
[ [ "the lingual tonsils develop at 6.5 weeks between the second and third arches ventrally while palatine tonsils develop at 8 weeks from second pouch ( ventral and dorsal ) .", "tonsils are particularly designed for direct transport of foreign material from the exterior to the lymphoid cells .", "both a...	objectives . tonsillitis is a common infection in all age groups , especially under the age of five . organisms causing this condition vary from place to place . our aim is to find out the main causative agents of this condition in our hospital . patients and methods . fifty - two consenting patients who needed tonsill...
[ [ "the present paper is aimed at reviewing findings of published studies investigating the prevalence of pei in diabetic patients and possible risk factors and mechanisms associated with its occurrence and severity .", "the cases of patients with type i and type ii diabetes will be discussed separately , in...	pancreas is a doubled - entity organ , with both an exocrine and an endocrine component , reciprocally interacting in a composed system whose function is relevant for digestion , absorption , and homeostasis of nutrients . thus , it is not surprising that disorders of the exocrine pancreas also affect the endocrine sys...
[ [ "seminal vesicle cysts are rarely diagnosed , but symptomatic congenital seminal vesicle cysts are reported in the literature describing zinner syndrome ." ], [ "a left seminal vesicle cyst and left kidney agenesis were found on examination , and the patient qualified for laparoscopic removal of the l...	introduction : seminal vesicle cysts are rarely diagnosed , but symptomatic congenital seminal vesicle cysts are reported in the literature describing zinner syndrome.case description : we present the case of a 26-year - old patient admitted to the urology department because of abdominal pain . a left seminal vesicle c...
[ [ "approximately 225,000 primary total hip arthroplasties ( thas ) are performed in the united states per year , and projections indicate that more than 4 million thas will be performed annually by 2030.1 neurologic injury after tha is reported to occur in 0.09 to 3.7% of primary thas and 0 to 7.4% of revision ...	background total hip arthroplasty ( tha ) is an established treatment for end - stage arthritis , congenital deformity , and trauma with good long - term clinical and functional outcomes . delayed sciatic nerve injury is a rare complication after tha that requires prompt diagnosis and management.methods we present ...
[ [ "therefore , the purpose of this study is to examine the effect of a 12-week pilates intervention on wellness of the elderly .", "considering the positive effects of physical activities in wellness for the elderly , in this study researcher introduces a new form of exercise known as pilates developed by j...	the purpose of this study is to examine the efficiency of 12-week pilates exercises on wellness in the elderly . before pilates exercises training , the 88 elderly ( 63 females , 25 males ) were given and completed a wellness scale . then , the elderly participated in pilates exercises and completed the same scale afte...
[ [ "this review presents a brief summary of their role in immunity with specific reference to human and animal tuberculosis and explores their potential as a novel approach to therapy or prophylaxis .", "tuberculosis remains the most important infectious disease globally , and mycobacterium tuberculosis is t...	human tuberculosis remains a huge global public health problem with an estimated 1/3rd of the population being infected . defensins are antibacterial cationic peptides produced by a number of cell types , most notably neutrophil granulocytes and epithelial cells . all three defensin types ( - , - , and -defensins ) hav...
[ [ "a comparison of their in vitro efficacy properties \n to those of jdtic show that several of the analogues were potent and \n selective opioid receptor antagonists .", ", we report the synthesis and in vitro efficacy as determined \n by [ s]gtps assay of jdtic analogues 415 ( see table 2 for structures ...	jdtic analogues 415 which have the hydroxyl groups replaced with other groups were synthesized and their in vitro efficacy at the , , and opioid receptors determined and compared to jdtic using [ 35s]gtps assays . compounds 4 , 5 , 6 , 13 , 14 , and 15 had ke = 0.024 , 0.01 , 0.039 , 0.02 , 0.11 , and 0.041 ...
[ [ "the most popular approach is the incorporation of the active poorly water soluble component into inert lipid vehicles such as oils , surfactant dispersions , solid dispersions , solid lipid nanoparticles , emulsions , microemulsions , nanoemulsions , self - emulsifying formulations ( sef ) , micro / nanoemul...	poorly water - soluble drug candidates are becoming more prevalent . it has been estimated that approximately 6070% of the drug molecules are insufficiently soluble in aqueous media and/or have very low permeability to allow for their adequate and reproducible absorption from the gastrointestinal tract ( git ) followin...
[ [ "our second purpose was to compare the anatomy of the maxillary sinus septa in dentate and edentate patients to determine if immediate implant placement in maxillary sinus septa is more favorable than delayed implant placement .", "the aim of this investigation was therefore to evaluate , in 3d , the maxi...	backgroundthe aim of our study was to investigate , in 3 dimensions , the maxillary sinus septa as an alternative site for dental implant placement to avoid sinus lift procedures.material/methodswe selected 100 dentate and 100 edentate patients with the presence of a maxillary sinus septum by reviewing a larger cone be...
[ [ "accumulation of smooth muscle cells ( smcs ) in the tunica intima plays a crucial role in the pathogenesis of vascular lesions , including atherosclerosis and restenosis following angioplasty or stenting procedures ( 1 , 2 ) . in the classical pathogenetic hypothesis of atherosclerosis , following injury gro...	intimal accumulation of smooth muscle cells contributes to the development and progression of atherosclerotic lesions and restenosis following endovascular procedures . arterial smooth muscle cells display heterogeneous phenotypes in both physiological and pathological conditions . in response to injury , dedifferentia...
[ [ "subjects in the present study are part of a longitudinal study of the etiology of type 2 diabetes among the gila river indian community in arizona , where most of the residents are pima indians or of the closely related tohono o'odham tribe . diabetes status was determined by an oral glucose tolerance test a...	objectivembl2 encodes the mannose - binding lectin , which is a key player in the innate immune system and has recently been found to play a role in insulin resistance and development of type 1 diabetes and gestational diabetes mellitus . to assess the role of mbl2 in diabetes susceptibility , this gene was analyzed in...
[ [ "histopathologically , basal cell hyperplasia , appearance of suprabasal cells with new proliferation capacity are observed in cholesteatoma , resulting in disruption of epidermal homeostasis between proliferation and terminal differentiation rate.2 - 4 ) involucrin is precursor of human cornified envelope an...	background and objectivesthe aim of this study is to determine whether the hyperproliferative and hyperkeratotic characters of cholesteatoma are associated with differentiation of keratinocytes in cholesteatoma by examining the localization of marker proteins , such as involucrin , filaggrin , and cytokeratins.material...
[ [], [ "we report a case of a 43-year - old male who sustained an electrical shock injury following which he fell from a height of around 4 feet .", "laboratory investigations revealed the patient had extremely low levels of vitamin d ( 11.1ng / ml ) ." ], [ "we report this case as a rare etiologic...	introduction : simultaneous bilateral fractures of the neck of femur is rare . hypocalcemia , epilepsy , osteoporosis and electrical injuries are known to cause similar injuries.case report : we report a case of a 43-year - old male who sustained an electrical shock injury following which he fell from a height of aroun...
[ [ "a product currently on the market , consisting of a hydro - soluble nail lacquer and containing hydroxypropyl - chitosan ( hpch ) , horsetail extract ( equisetum arvense ) , and methylsulfonylmethane , as its main ingredients , has shown its effectiveness in the management of nail splitting and nail brittlen...	backgroundnail psoriasis occurs in up to 50% of patients affected by psoriasis , with a significant impact on quality of life that leads to a real clinical need for new therapeutic options.aimto confirm whether the strengthening and hardening properties of the hydroxypropyl - chitosan ( hpch ) nail lacquer could improv...
[ [ "wu polyomavirus antigen in respiratory epithelial cells from lungs transplanted into a recipient ( 28-year - old woman ) with job syndrome .", "wu polyomavirus antigen in bronchoalveolar lavage specimens from lungs transplanted into a recipient ( 28-year - old woman ) with job syndrome .", "nn - ab06...	we detected wu polyomavirus ( wupyv ) in a bronchoalveolar lavage sample from lungs transplanted into a recipient with job syndrome by using immunoassays specific for the wupyv viral protein 1 . co - staining for an epithelial cell marker identified most wupyv viral protein 1positive cells as respiratory epithelial cel...
[ [], [ "the purpose of this study was to evaluate short - term ( median 18 months after surgery ) and medium - term ( median 4 years after the surgery ) results after open lateral release in recalcitrant tennis elbow and to determine any prognostic factors .", "tennis elbow ( te)also called lateral epico...	purposethe objectives of this study were to evaluate the results in the outpatient treatment of recalcitrant lateral epicondylitis with release of the common extensor origin according to hohmann and to determine any prognostic factors.methodseighty tennis elbows in 77 patients with a characteristic history of activity ...
[ [ "recent clinical research has provided evidence demonstrating that low - dose intravenous infusions of ketamine , a drug originally developed as an anaesthetic , can improve depressive symptoms within hours in subjects with treatment - resistant depression .", "we focus on three specific molecular mechani...	major depressive disorder is an extremely debilitating condition affecting millions of people worldwide . nevertheless , currently available antidepressant medications still have important limitations , such as a low response rate and a time lag for treatment response that represent a significant problem when dealing w...
[ [ "only two cases has been reported till date with gbs with total paresis of motor cranial nerves . here", "guillian barre syndrome ( gbs ) is associated in 45 - 75% of cases with cranial nerve involvement .", "facial nerve is the commonest to be involved followed by extra ocular muscles and lower crani...	guillian barre syndrome ( gbs ) is associated with cranial nerve involvement . commonest cranial nerves involved were the facial and bulbar ( ixth and xth ) . involvement of twelfth cranial nerve is rare in gbs . we present a case of gbs in a thirteen years old boy who developed severe tongue weakness and wasting at tw...
[ [ "the purpose of this study was to investigate the prevalence , distribution , position , and depth of impacted third molars ( itms ) in turkish orthodontic patients from a single academic institution .", "third molar impaction is the most commonly observed tooth impaction in modern communities , as the th...	objective : we aimed to investigate the prevalence , distribution , angular position , and depth of third molar impaction in a turkish orthodontic patient population.materials and methods : we retrospectively reviewed the panoramic radiographs , intraoral photographs , and dental casts of 207 patients ( 62 men and 145 ...
[ [ "primary hpt ( phpt ) is caused by parathyroid adenomas in 85% of cases , leading to hyperplasia and over - secretion of pth . in most individuals in western society , it is diagnosed at an asymptomatic stage , without signs or symptoms of ( pth ) calcium excess .", "initial symptoms are nonspecific , suc...	we present the case of a 22-year - old male with longstanding progressive fatigue , weakness and pain around his hips due to an undiagnosed parathyroid adenoma . the resultant primary hyperparathyroidism ultimately caused pathologic fractures . he was admitted to the hospital for further assessment and excision of the ...
[ [ "objectives of the study reported here were to identify values for measurement of hba1c percentage in blood samples obtained from nhps ( macaca fascicularis ) to determine whether these percentages varied with respect to glycemic control after diabetes induction and insulin treatment .", "glycated hemoglo...	non - human primates ( nhps ) are a very valuable experimental model for diabetes research studies including experimental pancreatic islet transplantation . in particular nhps are the recipients of choice to validate pigs as possible source of pancreatic islets . the aim of this study was to quantify glycated hemoglobi...
[ [ "this study was designed to compare the effect of dex as an analgesic and sedative drug with remifentanil as an adjuvant drug in anesthesia regiment in spinal operation . \n", "another sedative - hypnotic - analgesic drug with an acceptable effect is dexmedetomidine ( dex ) .", "remifentanil has been ...	background : controlling the hemodynamic situation of patients who have spinal operation is of prime importance , and maintaining the heart rate and blood pressure in normal or low- normal levels in these patients can reduce their bleeding loss . one of the commonly used drugs for this purpose is remifentanil . a...
[ [ "munchausen 's syndrome , in its classic description , is an uncommon subtype of factitious disorder which has received great attention.78 this syndrome is the earliest description of a factitious disorder with predominantly physical signs and symptoms .", "socio - cultural factors are important in the ep...	factitious disorders are characterized by physical or psychological manifestations that are intentionally produced or feigned with no apparent external incentives in order to assume the sick role . these disorders are rarely reported or may be under - reported in saudi patients . we describe here two male and female sa...
[ [ "the authors report the use of foreskin as skin graft to repair a loss of substance due to excision of an interdigital nevus of the foot .", "furthermore , the site of lesion could indicate surgical excision to prevent continuous microtraumas [ 13 ] .", "surgical excision could determine loss of sub...	we report a four - year - old boy with a nevus covering all the plantar side of his second finger on the left foot . he was also affected by congenital phimosis . surgical excision of the nevus was indicated , but the skin defect would have been too large to be directly closed . the foreskin was taken as a full - thi...
[ [ "scott analysis to explore whether the prevalence of established hc awareness , treatment , and control varied significantly among hispanic / latino groups and across categories of sep and acculturation . to assess whether health insurance status confounds the association of sep on hc awareness , treatment ,...	backgroundwe assessed high cholesterol ( hc ) awareness , treatment , and control rates among us hispanic / latino adults and describe factors associated with hc awareness and management.methods and resultsbaseline data ( collected 20082011 ) from a multisite probability sample of hispanic / latino adults in the hispan...
[ [ "gaucher disease ( gd ) is a rare autosomal recessive hereditary disorder of glycosphingolipid metabolism , characterized by the accumulation of glucosylceramide in cells of the reticulo - endothelial system , due to deficient activity of the lysosomal enzyme , beta - glucosidase ( glucocerebrosidase , ec 3.2...	bone complications occur frequently in gaucher disease ( gd ) and reduce the quality of life of these patients . skeletal involvement is an important indication for treatment to ameliorate symptoms and reduce the risk of irreversible and debilitating disease . bone biomarkers have been used to assess disease status and...
[ [ "in addition , the spawning amount , buoyancy rate and fertilization rate among spawned eggs , the size change of egg and oil droplet for buoyant eggs were investigated .", "this study therefore aimed to develop a method for the production of stable , healthy fertilized eggs from yellowtail kingfish . sin...	this study describes results on sexual maturation and characteristics of natural spawned eggs to develop a method for the production of stable , healthy fertilized eggs from captive - reared yellowtail kingfish , seriola lalandi . a total of 59 yellowtail kingfish were captured off the coast of jeju island , after whic...
[ [ "the authors present a case in which misdiagnosis and inappropriate treatment of a buccal cheek laceration due to an ill - fitting denture resulted in a buccal space abscess that progressed into cst .", "cavernous sinus thrombosis ( cst ) was first reported by bright et al . in 18311 .", "cst is an in...	cavernous sinus thrombosis not only presents with constitutional symptoms including fever , pain and swelling but also with specific findings such as proptosis , chemosis , periorbital swelling , and cranial nerve palsies . it is known to occur secondary to the spread of paranasal sinus infections in the nose , ethmoid...
[ [ "the aim of the present hospital - based clinical retrospective study was ( 1 ) to estimate the number of children being diagnosed with g93.3 postviral fatigue syndrome during a 10-year period ( 2002 to 2011 ) and ( 2 ) describe the clinical and laboratory findings in children with postviral fatigue syndrome ...	aim . to estimate number of children being diagnosed with chronic fatigue syndrome ( cfs ) . methods . for a period of 10 years ( 20022011 ) data from children being referred for fatigue symptoms were collected retrospectively . results . thirty - seven children were referred . four were excluded due to incorrect codin...
[ [ "the msqol-54 has been used in the united states and has proven a valuable instrument for measuring hrqol in ms [ 21 - 23 ] . the questionnaire has also been translated into both italian and french . the objective of this study was to translate the msqol-54 into french canadian , and to make it available to...	backgroundmultiple sclerosis ( ms ) is a neurodegenerative disease which runs its course for the remainder of the patient 's life frequently causing disability of varying degrees . negative effects on health - related quality of life ( hrqol ) are well documented and a subject of clinical study . the multiple sclerosis...
[ [ "insulin detemir has now become established as an effective basal insulin preparation and is widely used in the management of both type 1 and type 2 diabetes . although it is similar in efficacy to isophane insulin , we have observed a relative lack of efficacy in two patients with significant hypertriglyceri...	key clinical messageinsulin detemir is commonly used in obese patients with diabetes mellitus as it is considered hepatoselective and causes less weight gain . we describe a relative lack of effectiveness of detemir in patients with significant nafld and hypertriglyceridemia , compared to isophane insulin . this may af...
[ [ "diabetes , sudden nocturnal death ( dead in bed syndrome ) is rare .", "patients with coronary artery disease ( cad ) and diabetes have higher mortality and morbidity than patients without diabetes . data from studies such as", "episodes of severe hypoglycemia are common during intensive therapy in...	hypoglycemia is a very common side effect of insulin therapy and , to a lesser extent , of treatment with oral hypoglycemic agents . severe hypoglycemia can precipitate adverse cardiovascular outcomes such as myocardial ischemia and cardiac arrhythmia . these are mainly secondary to autonomic activation which results i...
[ [ "the purpose of this review is to illustrate the mechanisms in which aberrant fibronectin expression influences tumorigenesis and therapy resistance .", "further , this review will highlight potential strategies whereby fibronectin deposition , engagement with cell surface receptors and activation of cell...	fibronectin is a matrix glycoprotein which has not only been found to be over - expressed in several cancers , but has been shown to participate in several steps of tumorigenesis . the purpose of this review is to illustrate how aberrant fibronectin expression influences tumor growth , invasion , metastasis and therapy...
[ [ "the aim of this case report is to present a patient with rhinocerebral mucormycosis who was successfully treated due to timely diagnosis , effective surgical intervention , and intravenous antifungal treatment .", "it is caused by fungi , which may be found in decaying food , in the soil , or other organ...	this paper presents a case of rhinocerebral mucormycosis in a 22-year - old female patient with type i diabetes mellitus , who was successfully treated with surgery and long - term antifungal medication . the patient had initially been submitted to extraction of an upper third molar by a general dental practitioner but...
[ [ "drug discovery is a complex and expensive endeavor that usually requires seven major steps : disease selection , target hypothesis , lead compound identification ( screening ) , lead optimization , pre - clinical trial , clinical trial and pharmacogenomic optimization . among the various techniques used to f...	in silico screening based on the structures of the ligands or of the receptors has become an essential tool to facilitate the drug discovery process but compound collections are needed to carry out such in silico experiments . it has been recognized that absorption , distribution , metabolism , excretion and toxicity (...
[ [ "aniridia is a rare bilateral congenital malformation of iris due to neuro - ectodermal developmental defect secondary to a mutation in pax6 gene located on chromosome 11p13 .", "the incidence of aniridia is estimated to be 1 in 60,000 - 100,000 live births.1 it exists in both sporadic and familial form ....	aniridia is a rare congenital malformation that may be associated with various ocular and systemic manifestations . we describe two cases of familial total aniridia associated with microcornea , high myopia and dislocated lens . no systemic abnormality was noted in any of the cases .
[ [ "the aim of this study was to compare the efficacy , safety , and predictability of wf and cross - cylinder prk in moderateto- high astigmatism .", "however , data on high myopia are scarce.47 cross - cylinder prk is another technique of interest in astigmatism surgery .", "astigmatism treatment has a...	backgroundalthough there have been many studies of the efficacy and safety of wavefront- guided ( wf ) and cross - cylinder photorefractive keratectomy ( prk ) , there are few studies on moderate - to - high astigmatism cases . the aim of this study was to assess and compare the efficacy of wf and cross - cylinder prk ...
[ [ "compressibility of the tissue is a parameter evaluated by an elastogram and it is expressed as the change in tissue displacement as a function of its distance from the probe which is recognised as strain . among the 400450 lymph nodes ( lns ) of the human body , 6070 are located in the head and neck area .",...	background . it is crucial to differentiate between reactive and malignant lymphadenopathies . elastosonography measures the elasticity of the tissue . having a reference value for benign lymph nodes ( lns ) is important in interpretation . the purpose of this study is to determine the reference elastosonography values...
[ [ "the arthrodesis of the talonavicular joint and calcaneal - cuboid joint is technically complex in the presence of bone defect and there is a high incidence of nonunion .", "midfoot fractures and dislocations are uncommon because of the intrinsic stability of the tarsal structure .", "furthermore , in...	we present a 49-year - old man with a traumatic subamputation of the forefoot , associated with lacerated wound in correspondence of the dorsal surface of the right foot , with injuries of tendinous , ligamentous and vascular structures and with the loss of talus head . the patient underwent salvage arthrodesis of the ...
[ [ "we show how the paralimbic network uses information from both the external world and introspection to balance the resource allocation , and how the access and balance in this system is regulated by emotion and by neurotransmitters such as dopamine .", "we synthesize the evidence from the literature to sh...	consciousness has been proposed to play a key role in shaping flexible learning and as such is thought to confer an evolutionary advantage . attention and awareness are the perhaps most important underlying processes , yet their precise relationship is presently unclear . both of these processes must , however , serve ...
[ [ "the unpredictability of clinical course and the risk of airway compromise with not so high end airway management gears at hand make it more challenging in a rural health setup .", "a rare , potentially fatal and usually self - limiting adverse effect of therapy with enalapril , the angioedema , is always...	angioedema , a rare , potentially fatal and usually self - limiting adverse effect of therapy with enalapril , is always a challenging encounter for an intensive care specialist in a rural setup . here , we present a 74-year - old female , who presented to the emergency department of sekgoma memorial hospital , serowe ...
[ [ "the dosimetric accuracy of brachytherapy delivery is fundamental to the achievement of clinical treatment aims , tumour control and minimised normal tissue toxicity . as early as 1993 van dyk et al . ", "the publication of a comprehensive assessment of current qc practice has several potential benefits ...	purposea survey of quality control ( qc ) currently undertaken in uk radiotherapy centres for high dose rate ( hdr ) and pulsed dose rate ( pdr ) brachytherapy has been conducted . the purpose was to benchmark current accepted practice of tests , frequencies and tolerances to assure acceptable hdr / pdr equipment perfo...
[ [ "therefore , the aim of this study was to investigate the characteristics surrounding readmission for cancer patients after their first ipc admission in taiwan from 2002 to 2010 with the goal of informing future policy discussions .", "in addition , readmission is an indicator of quality of care and is re...	abstractfew studies have reported on readmissions among cancer patients receiving inpatient palliative care ( ipc ) . this study investigated readmissions in cancer patients after their first discharge from ipc in taiwan from 2002 to 2010.this study was a secondary data analysis using information from the national heal...
[ [ "reverse shoulder prosthesis is an excellent surgical option for patients with certain shoulder pathologies , of which rotator cuff arthropathy is one .", "we present a case of treatment of a fracture at the base of the acromion using a 90/90 plating construct that healed in a good position ." ], [ ...	fractures of the acromion and scapula are known to occur after reverse shoulder arthroplasty . we present a case of a fracture at the base of the acromion 5 months after arthroplasty treated successfully with dual plating of the acromion . eighteen months after fracture fixation , the patient had 160 degrees of active ...
[ [ "as the extra - cellular domain of fz , mainly the wnt binding crd , is necessary and sufficient for the non - autonomous function of fz , we revisited these issues and asked systematically , whether and how wnts might function in drosophila pcp generation .", "d ) indicate that the wnt gof pcp phenotypes...	planar cell polarity ( pcp ) is cellular polarity within the plane of an epithelial tissue or organ . pcp is established through interactions of the core frizzled(fz)/pcp factors and although their molecular interactions are beginning to be understood , the upstream input providing directional bias / polarity axis rema...
[ [ "the purpose of this study was to discern if physiological and qol - related benefits of yoga exist in individuals with pd .", "because overall function measured by the unified parkinson 's disease rating scale ( updrs ) was investigated , we wanted to discern whether yoga affects the non - motor aspects ...	background : exercise can be beneficial for cardiopulmonary , musculoskeletal or neurological systems , and other factors including mood , and may be beneficial in reducing fall risks , dementia and variables associated with quality of life ( qol ) . parkinson 's disease ( pd ) produces progressive motor and cognitive ...
[ [ "the purposes of this study were to examine the effect of exposure to af infection and elevated pro - inflammatory cytokine levels on the mortality and pulmonary , intestinal , and neurologic outcomes of preterm infants , and to determine whether these associations persist after adjustments are made for gesta...	to what extent the risks of neonatal morbidities are directly related to premature birth or to biological mechanisms of preterm birth remains uncertain . we aimed to examine the effect of exposure to amniotic fluid ( af ) infection and elevated cytokine levels on the mortality and pulmonary , intestinal , and neurologi...
[ [ "the annual incidence is estimated to be 73,510 . although most patients have non - invasive bladder tumors , 20 - 40% either present with or later develop muscle invasion .", "radical cystectomy ( rc ) is the standard surgical treatment for clinically localized muscle - invasive bladder cancer ( mibc ) ....	introduction : chemotherapy was shown to improve survival in patients undergoing radical cystectomy ( rc ) for muscle - invasive bladder cancer ( mibc ) . the initiation and completion rates for perioperative chemotherapy are variable . our aim is to compare the likelihood of initiating and completing neoadjuvant ( nac...
[ [ "patients with t - cell all and the m4 and m5 subtypes of acute myeloblastic leukemia are at a higher risk for extramedullary disease , including renal parenchymal involvement , which is the most frequent extramedullary metastatic site.1 consequences of leukemic infiltration of the kidneys are asymptomatic bi...	leukemic infiltration of the kidney is usually silent , and the admission of the patients with renal dysfunction or acute kidney injury is uncommon . we present a 34-year old hemodialysis patient with new onset of uncontrolled hypertension , erythropoietin - resistant anemia , thrombocytopenia , and bell s palsy . on a...
[ [ "a 72-year - old man presented with a two - week history of a red painful right eye .", "the cornea continued to heal and topical treatment for acanthamoeba ( including steroids and ofloxacin ) were continued and tailed off over a further three months . in all episodes of infection , antibiotic sensitivit...	recurrence of microbial keratitis in the presence of protozoal infection is very rare and infrequently reported unless predisposing factors are present . the association of recurrent microbial keratitis and synthetic microfibrils has never previously been reported to our knowledge . this single interventional case stud...
[ [ "the aims of this study were to investigate the expression and function of myo6 and related proteins in human macrophages and to test the hypothesis that myo6 plays a role in the endocytosis of ldl and/or oxldl by these cells .", "expression of myo6 ( including splice variants ) , dab2 , ap-22 ( one of th...	myosin vi ( myo6 ) functions in endocytosis in conjunction with binding partners including adaptor protein ( ap)-2 , disabled 2 ( dab2 ) , and gaip interacting protein c terminus 1 ( gipc1 ) . this study aimed to investigate the expression and function of myo6 in macrophages and its possible role in the endocytosis of ...
[ [ "the objective of this study was to analyze and compare the levels of lp - pla2 and hscrp as predictors of ms in subjects without atherosclerotic disease .", "metabolic syndrome ( ms ) is a group of cardiovascular ( cv ) risk factors including abdominal obesity , hypertriglyceridemia , low high - density ...	high sensitivity c - reactive protein ( hscrp ) is a marker of metabolic syndrome ( ms ) and cardiovascular ( cv ) disease . lipoprotein - associated phospholipase a2 ( lp - pla2 ) also predicts cv disease . there are no reports comparing these markers as predictors of ms . methods . cross - sectional study comparing l...
[ [ "spigelian hernias were named after the flemish anatomist , adrian van den spiegel , who was the first to describe the semilunar line .", "there is a weakness in the spigelian fascia that gives rise to a spigelian hernia , and this may be either congenital or acquired .", "a spigelian hernia is define...	highlightsthe combination of physical exam findings and imaging is usually sufficient for the diagnosis of spigelian hernias.patient with chronic lower abdominal pain and with normal physical exam and imaging studies revealed to have a spigelian hernia.diagnostic laparoscopy of patient with chronic lower abdominal pain...
[ [ "in total , we collected 70 horse samples including two european - origin breeds ( thoroughbred ; \n n=4 , selle franais ; n=1 ) , one south american - origin breed ( criollo ; n=5 ) , three native \n japanese breeds , and a native korean breed .", "we amplified 504 base pairs of the exon3 region in equin...	genetic polymorphisms in genes related to neurotransmitters or hormones affect personality or behavioral traits in many animal species including humans . in domestic animals , the allele frequency of such genes has been reported to be different among breeds and it may account for breed differences in behavior . i...
[ [ "\n pilomatricoma usually appears in the first two decadesusually , an asymptomatic lesion with an occasional inflammation . \n ", "pilomatricoma usually appears in the first two decades usually , an asymptomatic lesion with an occasional inflammation .", "usually , they present as a solitary nodule /...	pilomatricoma is a benign tumor arising from the hair matrical cells . most pilomatricomas appear in the first two decades of life as a solitary skin to a bluish colored nodule on head - neck area with an occasional sign of inflammation . here , we present a case of pilomatricoma which appeared at 36 years of age with ...
[ [ "the potential use of the affected upper extremity of children with hemiplegia often fails due to learned non - use phenomenon .", "constraint - induced movement therapy ( cimt ) is one of the treatment strategies which utilizes the principles of neural plasticity to help acquire motor skills of the aff...	infantile hemiplegia is one of the clinical forms of cerebral palsy that refers to impaired motor function of one half of the body owing to contralateral brain damage due to prenatal , perinatal and postnatal causes amongst which vascular lesion is the most common causative factor . we report here the effects of constr...
[ [ "the phosphoinositide 3-kinase ( pi3k)/akt survival pathway functions upstream to positively regulate the activity of the mtor axis .", "thus , mtor serves as a convergence point of the pi3k / akt and mitogen - activated protein kinase ( mapk)/erk signaling pathways , which are often hyperactivated in can...	rapamycin and its derivatives ( rapalogs ) , a group of allosteric inhibitors of mammalian target of rapamycin ( mtor ) , have been actively tested in a variety of cancer clinical trials , and some have been approved by the food and drug administration for the treatment of certain types of cancers . however , the singl...
[ [ ", we have recently shown that an acidic ph had a minor effect on voltage - gated na channels in acutely isolated vmes neurons .", "however , the generation and conduction of action potentials , and synaptic transmission at presynaptic nerve terminals also require other voltage - gated ion channels , such...	the effects of acidic ph on several voltage - dependent ion channels , such as voltage - dependent k+ and ca2 + channels , and hyperpolarization - gated and cyclic nucleotide - activated cation ( hcn ) channels , were examined using a whole - cell patch clamp technique on mechanically isolated rat mesencephalic trigemi...
[ [ "five diagnostic criteria for mets have been identified by the national cholesterol education program adult treatment panel iii ( ncep - atp iii ) , and the presence of any of these three features ", "about 24% of us adults have mets , and the prevalence increases with age ( 44% at age 60 years ) .", ...	metabolic syndrome is associated with increased propensity for diabetes and cardiovascular disease . low - grade inflammation is characteristic of metabolic syndrome . c - reactive protein , the best characterized biomarker of inflammation , is also an independent predictor of future cardiovascular events . this review...
[ [ "we experienced a rare case of myasthenia crisis during antiviral therapy for chc , in whom mediastinal thymoma was discovered and successfully managed with surgical thymectomy and meticulous medical care .", "standard care for chronic hepatitis c ( chc ) has been a combination of pegylated interferon - a...	abstractmyasthenia gravis is occasionally associated with thymoma that needs surgical resection and may progress to severe respiratory failure . we experienced a rare case of myasthenia crisis during antiviral therapy for chronic hepatitis c , in whom mediastinal thymoma was discovered and successfully managed with sur...
[ [ "the present study reports for the first time that mia activation by poly(i : c ) at early gestation , which can lead to impairments in multiple psychological domains , is associated with mitochondrial changes in immune the cells of adult offspring .", ", we sought to determine whether mia in pregnant dam...	maternal immune activation ( mia ) is a potential risk factor for autism spectrum disorder ( asd ) and schizophrenia ( sz ) . in rodents , mia results in changes in cytokine profiles and abnormal behaviors in the offspring that model these neuropsychiatric conditions . given the central role that mitochondria have in i...
[ [ "microscopic techniques like giemsa stained blood smear is the most appropriate for the diagnosis of acute babesiosis but the low sensitivity of these method do not permit to identify the carrier animals ( juyal et al .", "the present study was therefore undertaken to diagnose subclinical cases of babesio...	background : present investigation is based on the clinicopatho - biochemical alteration related to natural tick borne bovine babesiosis in punjab state.methods:blood samples from jugular vein of 542 bovines ( cattle 466 and buffaloes 76 ) having history of tick infestation , fever , hemoglobinurea or anemia were colle...
[ [ "in modern society , more people spend long periods working at computers , and experience \n increased work - related neck and back discomfort1 . remaining seated for long periods can cause problems for the spine , \n circulation , muscles , and joints2 . \n prolonged sitting is a risk factor for low back pai...	[ purpose ] this study examined the effects of a relaxation chair and resting with simple range of motion exercises during computer work and low back muscle strengthening exercises after computer work on pain and the flexion - relaxation ( fr ) ratio of one computer worker with lbp . [ subjects ] the subject of t...
[ [ "these multifaceted features endow hcn channels to work in many functions described below . in this paper", "hyperpolarization - activated and cyclic nucleotide - gated ( hcn ) channels , first identified in 1976 in the heart by noma and irisawa and characterized by brown and difrancesco and weiss and...	hyperpolarization - activated and cyclic nucleotide - gated ( hcn ) channels were first reported in heart cells and are recently known to be involved in a variety of neural functions in healthy and diseased brains . hcn channels generate inward currents when the membrane potential is hyperpolarized . voltage dependence...
[ [ "recently , we have observed internal mammary lymph node metastases diagnosed by f - fdg - pet / ct as a solitary recurrence site in 3 ovarian cancer patients .", "recurrent epithelial ovarian carcinoma has a poor prognosis and is almost always fatal [ 1 , 2 ] .", "although nodal metastases are well k...	internal mammary lymph nodes as solitary site of recurrent ovarian cancer have not been previously described . in this case report , 3 cases of late and very late isolated recurrence in internal mammary lymph nodes are presented . 18f - fdg - pet / ct allowed the diagnosis which was suspected by the increase of the ser...
[ [ "we discuss some of current knowledge about cellular targets and mechanisms through which stress and altered gc levels trigger changes in the brain that may lead towards the development and progression of neurodegenerative pathologies such as alzheimer 's ( ad ) and parkinson ( pd ) disease .", "both vuln...	stress and stress hormones , glucocorticoids ( gcs ) , exert widespread actions in central nervous system , ranging from the regulation of gene transcription , cellular signaling , modulation of synaptic structure , and transmission and glial function to behavior . their actions are mediated by glucocorticoid and miner...
[ [ "herein , we would like to report our efforts directed at deacetylation of n - acetyl purine and pyrimidine nucleoside analogues bearing a variety of protecting groups ( pgs ) at the hydroxyl moiety , commonly used in nucleoside chemistry , such as o - acetyl , o - tert - butyloxycarbonyl , o - tert - butyldi...	protection and deprotection strategies involving the n - acetyl group are widely utilized in nucleoside and nucleotide chemistry . herein , we present a mild and selective n - deacetylation methodology , applicable to purine and pyrimidine nucleosides , by means of schwartz 's reagent , compatible with most of the comm...
[ [ "we report a case of corneal perforation with preseptal cellulitis in a patient treated with systemic chemotherapy for acute lymphocytic leukemia ( all ) .", "systemic chemotherapy can lead to a variety of ocular complications , such as cicatricial ectropion , nasolacrimal duct stenosis , conjunctivitis ,...	we report a case of corneal perforation with preseptal cellulitis in a patient with acute lymphocytic leukemia ( all ) . a 17-yr - old female patient who was undergoing combination chemotherapy for all was referred due to upper lid swelling and pain in the right eye for 2 days . visual acuity in the right eye was 20/20...
[ [ "therefore , this study evaluated the effects of cutting efficacy of different diamond burs on the microleakage of resin composite restorations using total etch and self etch adhesive systems , and it also determined whether or not bur cutting efficacy had an impact on the results .", "studies have evalua...	objective : in this study , the effect of bur cutting efficacy was evaluated on microleakage of class v composite restorations with two adhesive systems.materials and methods : class v cavities were produced on sound extracted human teeth , which had been assigned randomly to one of six groups ( n=15 ) as follows : gro...
[ [ "this rare condition potentially signifies an unstable cervical spine . we will report a case of congenital isthmic defect of cervical spine and describe a cause of cervical isthmic defect , diagnostic radiographic finding and appropriate treatment of cervical spondylolysis or spondylolithesis", "cervical...	we report a case of rare cervical isthmic spondylolisthesis of c6 - 7 combined occult spinal bifida at c6 , and review the radiologic finding , different diagnosis and treatment . a 23-year old female presented nuchal , back pain after traffic accident . radiologic finding showed the 6th cervical isthmic defect , spond...
[ [ "whether hfhd is better than low - flux hemodialysis ( lfhd ) is still under debate . in this study , we compared the efficacy of hfhd and lfhd in reducing vascular calcification and serum fgf-23 levels in patients receiving maintenance hemodialysis .", "a major factor leading to cardiovascular disease in...	backgroundhigh- and low - flux hemodialysis ( hfhd and lfhd , respectively ) are dialysis procedures designed to eliminate blood toxins that accumulate in end - stage renal disease . hfhd may reduce vascular calcification by removing serum fibroblast growth factor 23 ( fgf-23 ) . however , whether hfhd is better than l...
[ [ "location of 3 villages in tengchong county , yunnan province , china , in which study of transmission risk from imported plasmodium vivax malaria was conducted .", "three villages ( manduo , luoping , and tuofeng ; figure ) in tengchong county , located in the westernmost part of yunnan province , were s...	malaria importation and local vector susceptibility to imported plasmodium vivax infection are a continuing risk along the china myanmar border . malaria transmission has been prevented in 3 border villages in tengchong county , yunnan province , china , by use of active fever surveillance , integrated vector control ...
[ [ ", there is not yet available data on diabetes burden at national level but one recent survey in saint - louis city ( northern region ) reported a prevalence of 10.4% with two - thirds of patients uncontrolled .", "the objective of this study was to compare prevalence and risk factors of diabetes in adult...	diabetes represents a challenging global health issue in the 21st century . data from sub - saharan african populations are scarce and are usually restricted to urban settings . the objective of this study was to compare prevalence and risk factors of diabetes in rural and urban areas in senegal . methods . in a commun...
[ [ "this study investigates the effect of prolonged use of stereoscopic display on visual fatigue and dorsolateral prefrontal cortex hemodynamic responses during visual display tasks .", "specifically , the neuroimaging of the brain in relation to visual fatigue can yield rich neurophysiologic data to object...	the purpose of this study was to investigate the effect of stereoscopic display alignment errors on visual fatigue and prefrontal cortical tissue hemodynamic responses . we collected hemodynamic data and perceptual ratings of visual fatigue while participants performed visual display tasks on 8 ft 6 ft nec lt silver...
[ [ "we describe life salvage of ecmo in a patient with cardiogenic shock and malignant arrhythmia caused by acute fulminant myocarditis .", "acute myocarditis is associated with various electrocardiogram ( ecg ) alterations , including st - t changes , q - waves , atrioventricular- and intraventricular - con...	clinical features of acute myocarditis range from a subclinical state to a fulminant state . fulminant myocarditis with ventricular arrhythmia or atrioventricular block is associated with a high mortality rate . in cases in which aggressive medical therapy for fulminant myocarditis is not likely to be successful , inte...
[ [ "moreover , in the last five years , technological advances in radiology and nuclear medicine gave us more understanding of the topography and metabolism of tumors , and a new dimension to optimize radiation therapy , including brachytherapy .", "all those developments are leading to a change in the parad...	this review summarizes the current understanding of the feasibility of functional imaging for brachytherapy . in following subsections the role of ultrasound , power doppler imaging , positron emission tomography , magnetic resonance imaging , dynamic dose calculation and targeted brachytherapy is analyzed . the combin...
[ [ "therefore , we compared the entire genomes of three different rabbit - passaged attenuated zb strains ( zb / cha/58(att ) , zbrf168 , and zbrf188 ) and their virulent parental viruses ( zbcf22 and ynbs/58 ) , in order to identify genomic changes that occurred during the attenuation process of the zb strain ....	the molecular basis of attenuation of foot - and - mouth disease virus ( fmdv ) serotype asia1 zb strain remains unknown . to understand the genetic changes of attenuation , we compared the entire genomes of three different rabbit - passaged attenuated zb strains ( zb / cha/58(att ) , zbrf168 , and zbrf188 ) and their ...
[ [ "agios pharmaceuticals is identifying metabolic pathways of cancer 135 cells and developing drugs to inhibit such enzymes in order to disrupt tumor cell growth and survival .", "l.c.c . owns equity in , receives compensation from , and serves on the board of directors and scientific advisory board of agio...	abstractserine metabolism is likely to play a critical role in cancer cell growth . a recent study reports the identification of a novel small - molecule inhibitor of serine synthesis that targets 3-phosphoglycerate dehydrogenase ( phgdh ) , the first enzyme of the serine synthesis pathway , and selectively abrogates t...
[ [ "this study was a case - control that was conducted in isfahan ; groups included 33 transurethral resection of the prostate ( turp ) patients ( group a ) and 33 patients who underwent open prostatectomy ( group b ) ; the cases were interviewed from 12 weeks to 12 months after undergoing surgery ( a total of 6...	background : irritable bowel syndrome ( ibs ) is a chronic functional bowel disorder that up to 20% of the population is suffering from it . also benign prostatic hyperplasia ( bph ) is a common problem that approximately 90 percent of men may be affected by this condition until the eighth decade of their life . prosta...
[ [ "acute disseminated encephalomyelitis ( adem ) is an autoimmune inflammatory disorder of the central nervous system ( cns ) .", "etiopathogenesis is thought to be immune mediated , because in up to three - fourths of the cases ; it follows an antecedent infection or immunization .", "currently for ade...	acute disseminated encephalomyelitis ( adem ) is a rare disease of central nervous system with myriads of presentation . it is a diagnosis of exclusion and relies on neuroimaging which may be normal at the onset . it is a diagnostic challenge at its first attack . here we present a case of adem which initially presente...
[ [ "colonic necrosis has been described as a rare complication after the administration of kayexalate [ 1 , 2 ] . in this case study , we present a case of calcium polystyrene sulfonate - induced colonic necrosis and perforation to remind clinicians of this rare , but dangerous , toxicity associated with this co...	sodium or calcium polystyrene sulfonate ( kayexalate or analog ) is an ion - exchange resin commonly used to treat hyperkalaemia in patients with chronic kidney disease . it is known to cause digestive complications , such as nausea , vomiting and constipation . although rare , colonic necrosis and perforation are very...
[ [ "these agents are indicated for the treatment of the pain associated with osteoarthritis of the knee in patients who have failed to respond adequately to conservative nonpharmacologic therapy and simple analgesics , eg , acetaminophen .", "have concluded that intra - articular corticosteroid injections pr...	intra - articular corticosteroid and hyaluronic acid injections provide short - term symptom amelioration for arthritic conditions involving structural damage or degenerative changes in the knee . conventional palpation - guided anatomical injections frequently result in inaccurate needle placement into extra - articul...
[ [ "development of spontaneous pneumopericardium is a very rare complication of tuberculosis with coexisting human immunodeficiency virus ( hiv ) infection . to the best of our knowledge", "only three cases of pneumopericardium with pulmonary tuberculosis concomitant with hiv infection[13 ] have been reporte...	pneumopericardium is defined as a collection of air or gas in the pericardial cavity . it is a rare entity and spontaneous pneumopericardium is even rarer . it is a rare complication of tuberculosis and human immunodeficiency virus and just three cases have been reported so far .
[ [ "complication following fracture of a central venous catheter can be catastrophic to both the patient and the attending doctor .", "catheter fracture has been attributed to several factors namely prolong mechanical force acting on the catheter , and forceful removal or insertion of the catheter ." ], ...	backgroundcomplication following fracture of a central venous catheter can be catastrophic to both the patient and the attending doctor . catheter fracture has been attributed to several factors namely prolong mechanical force acting on the catheter , and forceful removal or insertion of the catheter.case detailsin the...
[ [ "we used a computer model of a local neuronal circuit resembling the typical cell population of the hippocampus . in this model , the functional role of synaptic modification of the excitatory input to inhibitory interneurons was explored in a network biophysical simulation of cortical autoassociative memory ...	modulation of recurrent inhibition is critical not only for the normal function of highly excitable regions of the brain , especially the limbic system , but may also be a primary determining factor for the viability of neurons in these regions . standard extracellular and intracellular recordings from in vitro brain s...
[ [ "we report late presentation of crs in a 9 year old with scoliotic deformity with an asymptomatic cervical syrinx , in absence of any systemic abnormality .", "caudal regression syndrome ( crs ) is a rare disorder of distal spinal segments affecting the development of the spinal cord , with attendant sequ...	we report late presentation of caudal regression syndrome in a 9 year old presenting with a scoliotic deformity . she in addition had an asymptomatic cervical syrinx and vitiligo . we discuss the reasons for this unusual constellation of symptomatology present in our case .
[ [ "therefore , the purpose of this study was to investigate how participation in a recreation \n program influences changes in eeg findings in the demented elderly .", "however , there is still a lack of direct research on how \n activities for health promotion change electroencephalogram ( eeg ) findings i...	[ purpose ] this study investigated how participation in a recreation program influences electroencephalogram changes in the demented elderly . [ subjects ] fourteen patients were included in the experimental group and 18 in the control group . [ methods ] they had no regular exercise habits , and walked independ...
[ [ "these results indicate that ( pathologically ) increased theta band connectivity is related to a higher number of epileptic seizures in brain tumor patients , suggesting that theta band connectivity changes are a hallmark of tumor - related epilepsy .", "thus , functional connectivity and brain network a...	brain functions , including cognitive functions , are frequently disturbed in brain tumor patients . these disturbances may result from the tumor itself , but also from the treatment directed against the tumor . surgery , radiotherapy and chemotherapy all may affect cerebral functioning , both in a positive as well as ...
[ [ "the prevalence of diabetes mellitus has continued to rise worldwide with the latest estimation by the international diabetes federation that , by the year 2040 , one in 10 adults or 642 million people will have diabetes . tackling its rise and", "hong kong , returned to the sovereignty of china as a spec...	the hospital authority of hong kong is a statutory body that manages all the public medical care institutions in hong kong . there are currently around 400,000 diabetic patients under its care at 17 hospitals ( providing secondary care for 40% ) and 73 general outpatient clinics ( providing primary care for 60% ) . the...
[ [ "this paper describes the use of an adaptive community based participatory research ( cbpr ) process through which formative research data were collected for development of an sbhc intervention for prevention of metabolic syndrome in multiethnic high school students .", "this partnership led to the creati...	purpose . from our previous clinical work with overweight / obese youth , we identified the need for research to create an effective weight management intervention to address the growing prevalence of adolescent metabolic syndrome . formative assessment through an adaptive community - based participatory research ( cbp...
[ [ "it is caused by trauma , stress , sepsis , adrenal tumors , anticoagulation , hemorrhagic disorders and pregnancy .", ", whether the lesion is benign or malignant is an important issue but is difficult to determine prior to surgery .", "adrenal tumors associated with hemorrhage primarily include pheo...	we report herein a case of idiopathic adrenal hematoma . a 59-year - old japanese man was referred to our hospital for evaluation of a 7.0 cm mass in the right upper abdominal cavity . the tumor was suspected to originate from either the posterior segment of the liver or the right adrenal gland . his chief complaint wa...
[ [ "the aim of this study was to assess the impact of diabetes mellitus and hypertension as well as other demographic and clinical characteristics on perceived health status in primary health centers in oman .", "hypertensive patients with poor self - perceived health tend to have more visits.16 to our knowl...	objectives : this study aimed to assess the impact of diabetes mellitus and hypertension as well as other demographic and clinical characteristics on perceived health status in primary health centers in oman.methods:in a cross - sectional retrospective study , 450 patients ( aged 18 years ) seen at six primary health ...

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