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[ "two recent studies in bmc evolutionary biology on the effects of inbreeding in a seed beetle ( bilde et al . ) and in drosophila ( vermeulen et al . ) , respectively , provide additional insight into the genetic factors involved . differences in life span between males and females are commonly observed across many...	several possible and potentially overlapping genetic mechanisms have been suggested to explain differences in life span between males and females . two recent papers in bmc evolutionary biology on the effects of inbreeding provide additional insight into the genetic architecture underlying life span differences between...
[ "the present study was an attempt to assess the usefulness of serum pct as a marker of sepsis in critically ill patients , using the semi - quantitative , rapid immunochromatographic kit , in apollo hospitals , bangalore . sepsis can be difficult to distinguish from non - infectious conditions in critically ill or ...	sepsis can sometimes be difficult to substantiate , and its distinction from non - infectious conditions in critically ill patients is often a challenge . serum procalcitonin ( pct ) assay is one of the biomarkers of sepsis . the present study was aimed to assess the usefulness of pct assay in critically ill patients w...
[ "we used monthly reports of slide - confirmed malaria and annual census based population data from 434 counties ( municpios ) in the brazilian amazon region for 19961999 , during which no coordinated national malaria interventions occurred ( 12 ) . to study the relationship of reported malaria cases to climate , w...	climate changes are altering patterns of temperature and precipitation , potentially affecting regions of malaria transmission . we show that areas of the amazon basin with few wetlands show a variable relationship between precipitation and malaria , while areas with extensive wetlands show a negative relationship with...
[ "the clavicle is a rare site for bone tumours . according to the world health organisation , the giant cell tumor is an aggressive potentially malignant lesion which means that its evolution based on histological features is unpredictable . sites commonly affected by giant cell tumour are proximal tibia , distal fe...	highlightsgiant cell tumour of clavicle is a rare entity.the differntial diagnosis of giant cell tumour of clavicle which pose a diagnostic challenege gor both surgeon and histopathologist are aneurysmal bone cyst , non ossifying fibroma , tubercular osteomyelitis and eosniophilic granuloma.claviculecomy is a good opti...
[ "the aetiology of the development of pathological gambling in parkinson 's disease is still unclear , however , research suggests an association with dopamine replacement therapy , specifically with dopamine agonists ( voon et al . , 2006 ; this review summarizes evidence in this field of research attempting to re...	abstractthe incidence of pathological gambling in parkinson 's patients is significantly greater than in the general population . a correlation has been observed between dopamine agonist medication and the development of pathological gambling . however , scientists conjecture that the affected patients have underlying ...
[ "suicide is one of the leading causes of death throughout the world ; it ranks among the top 10 causes of death for individuals of all ages and is the leading cause of death in males under 35 years old.1,2 a decrease in the concentrations of serotonin metabolites ( in particular the serotonin 5-hydroxyindoleacetic ...	backgroundthe aim of this case control study was to explore the association by gender between the htr2c gene variants and suicidal behavior in a mexican population.subjects and methodsa total of 183 suicide attempters and 208 healthy volunteers were included in this study . we genotyped five polymorphisms of htr2c ( r...
[ "the deposition of glucan and mannoprotein - rich cell wall material on the mother and daughter side of the primary septum later completes the trilaminar septum that can be observed under normal culture conditions . a disturbance in the assembly of the septation apparatus the cohesive functional unit that construc...	boric acid ( ba ) has broad antimicrobial activity that makes it a popular treatment for yeast vaginitis in complementary and alternative medicine . in the model yeast s. cerevisiae , ba disturbs the cytoskeleton at the bud neck and impairs the assembly of the septation apparatus . ba treatment causes cells to form irr...
[ "although these objects are extracted either by endoscopy or laparoscopic gastrostomy , we devised an innovative technique by using pneumatic gastric insufflation and extracted the toothbrush by a tiny gastrotomy under local anesthesia . the pylorus , duodenal c - loop , and ileocecal valve are the three physiologi...	most of the ingested foreign bodies pass uneventfully through the gastrointestinal tract . however , long and rigid foreign bodies are associated with an increased risk of gastrointestinal impaction , perforation , and bleeding . spontaneous passage of a toothbrush has not been reported till date and the technique of i...
[ ", this study was performed to compare the effect of concept mapping with traditional nursing care plan on nursing students ct in clinical pediatric course . in iran , it can be stated that although ct is important in clinical judgments and decisions but during the training period , have had no significant developm...	introduction : concept map is a useful cognitive tool for enhancing a student 's critical thinking ( ct ) by encouraging students to process information deeply for understanding . however , the evidence regarding its effectiveness on nursing students ct is contradictory . this paper compares the effectiveness of concep...
[ "these include the \n intrinsic flexor pollicis brevis , flexor pollicis longus , lumbricalis , flexor brevis , and \n flexor longus muscles1 . we \n believe it is important to elucidate the contribution of femoral muscles to toe - gripping \n strength . in the present study , we investigated femoral muscle activit...	[ purpose ] in the present study , we investigated femoral muscle activity during toe - gripping , and the role of the femoral muscles in toe - gripping strength . [ subjects ] fourteen healthy young women were selected . [ methods ] we measured the maximum voluntary contraction of the rectus femoris and long hea...
[ "hence , in the present study we addressed the question if affective evaluations of dementia patients can be manipulated using a standard evaluative conditioning paradigm . thus , explicit knowledge about the cs - ucs relation seems crucial in fear conditioning while evaluative conditioning can be demonstrated in t...	we present results of a study investigating evaluative learning in dementia patients with a classic evaluative conditioning paradigm . picture pairs of three unfamiliar faces with liked , disliked , or neutral faces , that were rated prior to the presentation , were presented 10 times each to a group of dementia patien...
[ "internal herniation of a small bowel behind the external iliac artery after lymphadenectomy is a very rare complication to this procedure and to our knowledge only reported twice in the literature . in the first paper published in 1978 the author described how they managed their patient with laparotomy and resecti...	introductioninternal herniation of a small bowel behind pelvic vessels is a rare complication seen after pelvic lymphadenectomy.presentation of casea 56-year - old woman was operated due to a gynecological cancer . 4 years thereafter she presented with a 2 days history of abdominal pain and vomiting . clinical and radi...
[ "herein , we report ( i ) the modified synthetic approach to 3-(1h - benzimidazol-2-yl)-1h - pyrazolo[3,4-b]pyridines ( recall chart 1 : l1 , x = h , y = h ; l2 , x = br ; y = h ; l3 , x = br ; y = ch2och3 ) ; ( ii ) the synthesis and characterization of a new family of organoruthenium(ii ) ( 11a , 12a , 13a ) and ...	six organometallic complexes of the general formula [ miicl(6-p - cymene)(l)]cl , where m = ru ( 11a , 12a , 13a ) or os ( 11b , 12b , 13b ) and l = 3-(1h - benzimidazol-2-yl)-1h - pyrazolo[3,4-b]pyridines ( l1l3 ) have been synthesized . the latter are known as potential cyclin - dependent kinase ( cdk ) inhibitors . ...
[ "this paper highlights a rare entity of psjof involving the maxillary sinus and nasal cavity on the left side . fibro - osseous lesions of the jaws represent a diverse group of entities which include developmental ( hamartomatous ) lesions , reactive or dysplastic processes and neoplasms . the term juvenile psammom...	juvenile ossifying fibroma ( jof ) is an uncommon , benign , bone - forming neoplasm with an aggressive local growth that is distinguished from other fibro - osseous lesions primarily by its age of onset , clinical presentation and aggressive behaviour . jof is considered as a variant of the ossifying fibroma ( of ) an...
[ "when possible an endoscopic approach should generally be attempted in all patients with pseudocysts , and for pancreatic fluid collections endoscopic transmural drainage is the treatment of choice . endoscopic methods are among the most important and frequently employed means of treating pancreatic pseudocysts . t...	endoscopic drainage is a widely used treatment for pancreatic pseudocysts . drainage - related complications may be related directly to the procedure or may occur later as stents migrate or erode into adjacent structures . migration of a self - expanding metal stent into peritoneal cavity and incorporation in the oment...
[ "adenomyoepithelioma has been described as a rare benign neoplasm that occurs almost exclusively in the breast . in the breast we present the case of a 53-year - old woman with a clinically benign nodular cutaneous lesion that revealed histopathologic and immunohistochemical features of adenomyoepithelioma . it is ...	analogous to adenomyoepitheliomas of the breast , cutaneous adenomyoepithelioma is composed of two components , one being myoepithelial , the other ductal epithelial , and it lies in the spectrum of neoplasms having a pure myoepithelioma at one end and a mixed apocrine tumor at the other . we present the case of a 53...
[ "consequently , a more accurate , robust and faster method that does not rely on sequence alignment is needed to distinguish ncrnas , especially lncrnas , from protein - coding genes . here , we present coding - potential assessment tool ( cpat ) , an alignment - free program , which uses logistic regression to dis...	thousands of novel transcripts have been identified using deep transcriptome sequencing . this discovery of large and hidden transcriptome rejuvenates the demand for methods that can rapidly distinguish between coding and noncoding rna . here , we present a novel alignment - free method , coding potential assessment to...
[ "beyond its role of cellular energy currency and phosphate donor , atp plays a potent signaling role through its extracellular release and activation of cell surface purinergic receptors . do release other nucleotides including utp and udp - sugars but our focus here is atp release . mechanisms of atp release durin...	release and reception of extracellular atp by leukocytes plays a critical role in immune responses to infection , injury and cardiovascular disease . leukocytes of both the innate , adaptive immune and central nervous system express a repertoire of cell surface receptors for atp ( p2x and p2y receptors ) and its metabo...
[ "also , transfection of pon1-deficient peritoneal macrophages ( isolated from pon1 knockout mice ) with human pon1 decreased level of peroxides , lowered release of superoxide , and increased intracellular level of reduced glutathione , key observations are summarized in table 1 . summary of key facts on pon1 expre...	paraoxonase 1 ( pon1 ) is a hydrolytic enzyme with wide range of substrates , and capability to protect against lipid oxidation . despite of the large number of compounds that can be hydrolyzed by paraoxonase , the biologically relevant substrates are still not clearly determined . there is a massive in vitro and in vi...
[ "although uterine infarction is a relatively common occurrence after uae for the treatment of fibroids or adenomyosis , uterine infarction after ivf - et in a patient with adenomyosis is very rare . to our knowledge , this is the first report of uterine infarction after ivf - et in a patient with uterine adenomyosi...	adenomyosis is a common gynecological disorder characterized by the presence of endometrial glands and stroma deep within the myometrium associated with myometrial hypertrophy and hyperplasia . focal uterine infarction after ivf - et in a patient with adenomyosis following biochemical pregnancy has not been previously ...
[ ", transumbilical single - port surgery uses an umbilical single incision technique to access the peritoneal cavity and target organs . owing to the nature of umbilicus , single - port laparoscopy through the umbilicus offers an exciting opportunity to perform laparoscopic surgery with no visible scar . however , t...	objectives . to present our initial experiences with laparoscopically assisted vaginal hysterectomy performed using homemade transumbilical single - port system . materials and methods . we reviewed the medical records of one hundred patients who underwent single - port access laparoscopically assisted vaginal hysterec...
[ "drug eruptions are common , affecting 23% of all hospitalized patients , and complications associated with medications make up the largest proportion of adverse events seen in hospitals . we present 3 cases that highlight these difficulties and the broad spectrum of drug eruptions in the setting of lymphoma patien...	cutaneous drug reactions make up the largest proportion of adverse events in the medical field . causality , in particular , is difficult to determine , and therefore , preventing recurrent reactions can be challenging . bendamustine was initially thought to be a well - tolerated chemotherapy agent with few side effect...
[ "although indomethacin is usually well tolerated , some patients developed gastrointestinal side effects , specially those patients who require long term therapy . therefore , the use of cyclo - oxygenase-2 specific inhibitors could reduce secondary effects and they are essentially equipotent to indomethacin in vit...	paroxysmal hemicrania and hemicrania continua are both indomethacin - responsive headaches . although indomethacin use to be well tolerated , some patients developed gastrointestinal side effects . we report four cases of hemicrania continua and a patient suffering chronic paroxysmal hemicrania completely responsive to...
[ "according to early treatment of diabetic retinopathy study ( etdrs ) , protocol panretinal photocoagulation ( prp ) can prevent severe visual loss in proliferative diabetic retinopathy ( pdr ) . several studies have shown histopathologic changes in choroid of diabetic patients [ 24 ] . meanwhile , using panretinal...	purpose . to compare subfoveal choroidal , central retinal , and peripapillary nerve fiber layer ( rnfl ) thickness after panretinal photocoagulation ( prp ) with red and green laser in diabetic patients . study design . randomized clinical trial . methods . a total of 50 patients with bilateral proliferative diabetic ...
[ "the objective of this analysis was to estimate the cost - effectiveness of erlotinib versus best supportive care when used as first - line maintenance therapy for patients with locally advanced or metastatic nsclc and stable disease following first - line therapy in three european countries , ie , france , germany...	backgroundplatinum - doublet , first - line treatment of locally advanced or metastatic non - small cell lung cancer ( nsclc ) is limited to 46 cycles . an alternative strategy used to prolong the duration of first - line treatment and extend survival in metastatic nsclc is first - line maintenance therapy . erlotinib ...
[ "therefore , we hypothesised that if we administer la and the adjuvants separately , it may minimise the effect of the changes in densities and also hence their actions . thus , in this study we aimed to compare block characteristics , intra - operative haemodynamics and post - operative pain relief in parturients ...	background and aims : mixing adjuvants with hyperbaric bupivacaine in a single syringe before injecting the drugs intrathecally is an age old practice . in doing so , the density of the hyperbaric solution and also of the adjuvant drugs may be altered , thus affecting the spread of drugs . administering local anaesthet...
[ "thus , we report the perioperative outcomes of 106 consecutive patients treated with partial nephrectomy by a single surgeon using all three surgical approaches opn , lpn , and rpn . in experienced hands , laparoscopic partial nephrectomy ( lpn ) is associated with similar oncologic outcomes to open partial nephr...	objective . to report the perioperative outcomes of patients treated with partial nephrectomy by a single surgeon using three surgical modalities open , laparoscopic , and robotic . methods . between august 2006 and february 2012 , 106 consecutive patients underwent open partial nephrectomy ( opn ) ( n = 23 ) , laparos...
[ "job syndrome is one of the hyper immunoglobulin e ( ige ) syndrome ( hies ) conditions characterized by signal transducer and activator of transcription 3 ( stat3 ) signaling mutations . , it was hypothesized that there would be a lower incidence of clinical anaphylaxis among pediatric job syndrome patients . pati...	patients with autosomal - dominant ( ad ) hyper immunoglobulin e ( ige ) syndrome ( hies ) or job syndrome develop frequent dermatologic and pulmonary infections . as patients have an extreme elevation of ige levels , this database analysis study sought to study the association between ad hies , job syndrome , and anap...
[ ", the exhibition of markers of apoptosis by the parasite could be a contributing factor during host - parasite interactions as a possible immunosuppressive mechanism of dcl . once infecting mammalian hosts , these organisms , from free - living protozoa , become obligate intracellular parasites , residing and prol...	leishmania amazonensis parasites cause progressive disease in most inbred mouse strains and are associated with the development of diffuse cutaneous leishmaniasis in humans . the poor activation of an effective cellular response is correlated with the ability of these parasites to infect mononuclear phagocytic cells wi...
[ "despite of presentation of medical ethics as a new science in academic teaching , the ethical concepts have been alongside the medicine , and its antiquity back to the medicine history . taken together , we decided to evaluate the nurses knowledge about patients rights in one of the teaching hospitals of tehran ci...	patients rights observance is one of the effective measures of patients satisfaction of health care services . we performed this study at the aim of evaluation of nurses awareness of patients rights in a teaching hospital in tehran.this cross - sectional study was conducted in 2010 . in this study 156 nurses were rando...
[ "our study cohort consisted of 5,465 singleton children of european ancestry with recorded birth weight information . we performed high - throughput genome - wide single nucleotide polymorphism ( snp ) genotyping using the illumina infinium ii humanhap550 or human 610 beadchip technology ( illumina , san diego , ca...	objectivea number of studies have found that reduced birth weight is associated with type 2 diabetes later in life ; however , the underlying mechanism for this correlation remains unresolved . recently , association has been demonstrated between low birth weight and single nucleotide polymorphisms ( snps ) at the cdka...
[ "the aim of this study was to determine how physical ( weight , volume , and density ) and morphological ( md and bl dimensions ) properties affect the fracture resistance of roots , and which criteria are important for standardization in fracture resistance evaluated studies . the null hypothesis was that differen...	objective : the aim of this study was to determine how physical and morphological properties affect the fracture resistance of roots , and which criteria are important for root specimen standardization in fracture resistance studies.materials and methods : seventy - five freshly extracted human canine teeth were select...
[ "intensive insulin therapy using basal - bolus insulin regimen is the standard therapy for patients with type 1 diabetes mellitus . by mimicking the endogenous insulin secretion profile in healthy subjects , could provide great benefit to patients with type 1 diabetes . in this study , to evaluate the efficacy of i...	the aim of this study was to investigate the efficacy of insulin degludec used for basal - bolus insulin regimen after switching from twice - daily basal insulin in japanese patients with type 1 diabetes mellitus . the subjects were 22 type 1 diabetes patients treated with basal - bolus insulin regimen with twice - dai...
[ "a 33 year old healthy male of afro - caribbean origin presented to the emergency department with acute generalised abdominal pain of three hours duration . he was subsequently referred to a specialist in a distant tertiary unit for further evaluation of the residual tumour and for the prospect of further elective ...	desmoid tumours are benign tumours originating from the musculoaponeurotic structures of the body . they are mainly composed of collagen . these tumours commonly occur in post - partum women in whom they originate from the rectus abominus and in old surgical incisions . here we present a case report of a young gentlema...
[ "the technical success of tae was defined as the complete disappearance of arterial bleeding following tae . technically impossible or incomplete the following items were documented retrospectively : the presumptive causes and locations of arterial bleeding , the technical and clinical success rates of tae , and th...	objectiveto analyze the causes of arterial bleeding after living donor liver transplantation ( ldlt ) and to evaluate the efficacy of transcatheter arterial embolization ( tae).materials and methodsforty - two sessions of conventional arteriography were performed in 32 of the 195 patients who underwent ldlt during the ...
[ "fibrodysplasia ossificans progressiva ( fop ) is a rare genetic disoder characterized by bone formation within muscles tendons and ligaments . we hereby report a case of fop in a four year male child from a tribal family in orissa .", "4 yr old male child presented with gradual development of stiffness of neck a...	introduction : fibrodysplasia ossificans progressiva ( fop ) is a rare genetic disoder characterized by bone formation within muscles tendons and ligaments . it has an incidence of one in two million . we hereby report a case of fop in a four year male child from a tribal family in orissa.case report:4 yr old male chil...
[ ". herein we report transfection efficiencies , cytotoxicity profiles , and biophysical structure / activity studies for a new class of water - soluble c60 vectors prepared using the hirschbingel reaction which is one of the simplest , highest - yielding , and most versatile c60 functionalization methods known . as...	a new class of water - soluble c60 transfecting agents has been prepared using hirschbingel chemistry and assessed for their ability to act as gene - delivery vectors in vitro . in an effort to elucidate the relationship between the hydrophobicity of the fullerene core , the hydrophilicity of the water - solubilizing g...
[ "previously we reported that deletion of neutral endopeptidase ( nep ) provides protection from obesity- and diabetes - induced neural complications . however , little information is available about the effect of vasopeptidase inhibitors in animal models of diet - induced obesity . in order to further elucidate the...	we have demonstrated that treating diet - induced obese ( dio ) mice with the vasopeptidase inhibitor ilepatril improved neural function . vasopeptidase inhibitors block angiotensin - converting enzyme ( ace ) and neutral endopeptidase ( nep ) activity . we propose that increased activity of ace and nep contributes to ...
[ "they are effective against both gram - positive and gram - negative bacteria and , due to the relative lack of major side effects and cheap cost , have been used extensively in the treatment of infections as well as growth promoters in animal husbandry . bacterial resistance to , a study by caryl et al . reported ...	first reported in 2003 , mosaic tetracycline resistance genes are a subgroup of the genes encoding ribosomal protection proteins ( rpps ) . they are formed when two or more rpp - encoding genes recombine resulting in a functional chimera . to date , the majority of mosaic genes are derived from sections of three rpp ge...
[ "metastasis to skull and skin as the presenting feature of ftc is infrequently reported in the literature . skull and skin are uncommon sites and usually manifest well after the diagnosis of primary malignancy . follicular thyroid cancer ( ftc ) metastasizes most commonly to the lungs and non - cranial bones .", ...	backgroundfollicular thyroid cancer ( ftc ) metastasizes most commonly to the lungs and non - cranial bones . skull and skin are uncommon sites and usually manifest well after the diagnosis of primary malignancy . metastasis to skull and skin as the presenting feature of ftc is infrequently reported in the literature.c...
[ "thus , the aims of this study were to investigate whether metal interferes with the surface hardness and roughness of a visible light - polymerized acrylic resin and to compare these values to those of water - bath- and microwave - polymerized resins . in addition , light - polymerized resins can be processed dire...	although visible light - polymerized acrylic resins have been used in removable partial dentures , it is not clear whether the presence of a metal framework could interfere with their polymerization , by possibly reflecting the light and affecting important properties , such as roughness and hardness , which would cons...
[ "however , some studies debate on the effective and beneficial method of skin cancer screening as mass screening or high risk group screening and the real impact of skin cancer screening result on the society health . in iran , there are limited studies about prevalence and incidence of skin cancers . the two most ...	background : early detection of skin cancers by screening could be very beneficial to decrease their morbidity or mortality . there is limited study about skin cancer screening in iran.aim:this essay was planned as a pilot skin cancer screening campaign in tehran , iran to evaluate its profit and failure and further de...
[ "there is no report about the effects of combination therapy after avf creation using clopidogrel in combination with prostacycline analog as a potent vasodilator agent after autogenous avf creation . on the basis of these considerations , we performed a study to test the hypothesis that clopidogrel as an irreversi...	vascular access is used as a lifeline for hemodialysis in patients with end stage renal disease failure ( esrd ) . failure of arteriovenous fistula ( avf ) maturation is still high . the purpose of this study was to research the effects of clopidogrel in combination with oral iloprost , a synthetic analog of prostacycl...
[ "the objective of this study was to determine the efficacy and complication associated with transurethral removal ( tur ) of the intravesical or intraurethral mesh following midurethral sling procedures . tension - free vaginal tape ( tvt ) is now the treatment of choice for female stress urinary incontinence becau...	purposeto present outcomes of transurethral removal ( tur ) of intravesical or intraurethral mesh after midurethral slings.materials and methodsthis was a retrospective chart review of 23 consecutive women : 20 with intravesical mesh and 3 with intraurethral mesh.resultsto remove the mesh , transurethral resection with...
[ "finally , self - reported quality of life , disability and other patient - reported - outcomes were studied as a measure of the overall well - being of gad patients . the current study examined prospectively the evolution of gad symptoms in two groups of diagnosed patients in public and private mental healthcare s...	objective : to elucidate the consequences of broadening dsm - iv criteria for generalized anxiety disorder ( gad ) , we examined prospectively the evolution of gad symptoms in two groups of patients ; one group diagnosed according to dsm - iv criteria and the other , according to broader criteria.method:multicentre , p...
[ "the aim of this study was to determine whether a minimum set of criteria could be established to identify suspected hereditary renal cell cancer patients when there is restricted information about the familial occurrence of disease . renal clear cell carcinomas represent about 3% of all visceral cancers and accoun...	renal clear cell carcinomas represent about 3% of all visceral cancers and account for approximately 85% of renal cancers in adults . environmental and genetic factors are involved in the development of renal cancer . although to date there are 19 hereditary syndromes described in which renal cell cancer may occur , on...
[ "we report a case of a 54-year - old man who was successfully treated with epidural blood patches for intracranial hypotension due to csf leakage into the lumbosacral area after l4 - 5 discectomy . intracranial hypotension syndrome ( ihs ) is characterized by a postural headache that is aggravated in the erect or s...	intracranial hypotension syndrome typically occurs spontaneously or iatrogenically . it can be associated with headache , drowsy mentality and intracranial heamorrhage . iatrogenic intracranial hypotension can occur due to dural pucture , trauma and spine surgery . treatment may include conservative therapy and operati...
[ "we report the cases of two children with \n xanthogranuloma of the sellar region , presenting central diabetes insipidus ( di ) . , there is no detailed clinical report of xanthogranuloma of the \n sellar region in cases of pediatric age . here , pituitary insufficiency in childhood is often secondary to pituitary...	we report the cases of two japanese children with cystic pituitary enlargement on magnetic resonance imaging ( mri ) causing central diabetes insipidus ( di ) . in the first patient , endocrinological examination demonstrated slightly impaired growth hormone and thyroid stimulating hormone secretions , but normal...
[ "a 52-year - old female patient visited the hospital complaining of pain in both breasts . the patient was laid on her side and the epidural space was checked using the loss - of - resistance method with a 22-gauge epidural needle ( hakko , japan ) in between the t4 and t5 , applying an aseptic technique in the int...	breast surgery is a common procedure performed in women . many women who undergo breast surgery suffer from ill - defined pain syndromes . a nerve block is used in the treatment of the acute and chronic pain , but the effectiveness of the treatment has been limited because of its short duration . recently , the advent ...
[ "the algorithm uses the translation reading frames predicted by using blastx ( 2 ) as a guide for the identification of the coding region in sequences that have a hit ( 3 ) and predicts a coding region ab initio for sequences without a hit . we have implemented a web server called orfpredictor for the prediction of...	orfpredictor is a web server designed for identifying protein - coding regions in expressed sequence tag ( est)-derived sequences . for query sequences with a hit in blastx , the program predicts the coding regions based on the translation reading frames identified in blastx alignments , otherwise , it predicts the mos...
[ "we tested our apparatus by measuring absorption spectra on the eyespot and chloroplast of the unicellular alga dunaliella and emission spectra on the photoreceptor and chloroplast of the unicellular alga euglena gracilis . the photosynthetic and the photoreceptive compartments are the main location of chromophores...	a microspectrophotometer is a digital microscope used to measure absorption and fluorescence spectra . in this paper we describe a polychromator - based microspectrophotometer that performs in vivo absorption or emission measurements at the same time on different subcellular compartments such as photoreceptive and phot...
[ "the mammalian target of rapamycin ( mtor ) , a conserved serine - threonine protein kinase that is inhibited by the effective clinical immunosuppressant rapamycin , regulates several intracellular processes in response to various extracellular signals and thereby modulates mrna translation . accordingly , we used ...	the mammalian target of rapamycin ( mtor ) , a serine - threonine protein kinase , integrates extracellular signals , thereby modulating several physiological and pathological processes , including pain . previous studies have suggested that rapamycin ( an mtor inhibitor ) can attenuate nociceptive behaviors in many pa...
[ "while negative laparotomy was previously accepted as the inevitable and innocuous result of this policy , recent reports by renz and others have highlighted the 6 - 40% incidence of complications that accompany nontheraputic abdominal exploration . in view of these data , and how should the stable patient with pen...	background : how should the stable patient with penetrating abdominal or lower chest trauma be evaluated ? evolving trends have recently included the use of diagnostic laparoscopy . in september 1995 we instituted a protocol of diagnostic laparoscopy to identify those patients who could safely avoid surgical interventi...
[ "the aim of this work was to use a simple , rapid , and sensitive spectrophotometric method ( dithizone as chromogenic reagent ) for determination of trace amounts of selenium ( iv ) ( 5100 ng ml ) in micellar medium ( triton x-100 ) in cosmetic and pharmaceutical products . to improve the detection limit of this...	a simple , rapid , and sensitive spectrophotometric method for the determination of trace amounts of selenium ( iv ) was described . in this method , all selenium spices reduced to selenium ( iv ) using 6 m hcl . cloud point extraction was applied as a preconcentration method for spectrophotometric determination of s...
[ "data on individuals aged 029 years diagnosed with any type of diabetes ( excluding gestational ) from 1 january 1991 to 31 december 2006 were extracted from clinical notes by a dedicated register manager and entered onto the population - based yorkshire register of diabetes in children and young people for residen...	objectiveto investigate incidence trends of all diabetes types in all children and young people and in the south asian subpopulation.research design and methodsannual incidence per 100,000 and time trends ( 19912006 ) were analyzed for 2,889 individuals aged 029 years diagnosed with diabetes while resident in west york...
[ "familial adenomatous polyposis ( fap ) is a rare cause of colorectal cancer and is caused by a wide spectrum of mutations in the apc gene.1 \n 2 fap usually presents with a 100 to 1,000 of precancerous colonic polyps . without colectomy , although it is most frequently observed in the first decade of life , with 7...	gardner fibromas ( gfs ) have only recently been described as poorly circumscribed tumor - like lesions , which are exceedingly rare in children . gfs are associated with apc gene mutations and therefore with familial adenomatous polyposis ( fap ) . so far there is only very limited literature on gf in the neonatal per...
[ "we present two cases of type 2 dm with ds and believe that this is the first report of type dm with ds . down 's syndrome ( ds ) is one of the common chromosomal disorders and the most common cause of mental retardation . it is well - known that patients with ds have an increased prevalence of autoimmune disorders...	down 's syndrome ( ds ) is known to be associated with autoimmune disease including type 1 diabetes . to the best of our knowledge , there are no reports of ds with type 2 diabetes mellitus in the literature . we hereby report two cases of ds with type 2 diabetes .
[ "the challenge that remains is how to unlock the neurogenic potentials of the mammalian mg in vivo . recent progress in our understanding of brain development has significantly altered concepts for treating neurodegenerative diseases , including those that affect the retina to cause blindness . contrary to previous...	mller glia ( mg ) are the primary support cells in the vertebrate retina , regulating homeostasis in one of the most metabolically active tissues . in lower vertebrates such as fish , they respond to injury by proliferating and reprogramming to regenerate retinal neurons . in mammals , mg may also react to injury by pr...
[ "recently our own group has started to investigate the use of diamines in a bimetallic context , reporting in a communication the synthesis of the diazaethene zincate complex ( tmeda)li[(ipr)nch = chn(ipr)]zn(tbu ) 1 . the field of utility organometallics is increasingly turning to more complex mixed - metal system...	the surprising transformation of the saturated diamine ( ipr)nhch2ch2nh(ipr ) to the unsaturated diazaethene [ ( ipr)nch = chn(ipr)]2- via the synergic mixture nbum , ( tbu)2zn and tmeda ( where m = li , na ; tmeda = n , n , n,n-tetramethylethylenediamine ) has been investigated by multinuclear nmr spectroscopic studie...
[ "a gestational age of 40 weeks was assigned to 3 ( 27% ) of 11 infants with bacteremia and 4 ( 14% ) of 28 infants with meningitis who were reported as born following term gestation without a specific gestational age mentioned . we reviewed the literature for reports of e. sakazakii disease in infants . using medic...	enterobacter sakazakii kills 40%80% of infected infants and has been associated with powdered formula . we analyzed 46 cases of invasive infant e. sakazakii infection to define risk factors and guide prevention and treatment . twelve infants had bacteremia , 33 had meningitis , and 1 had a urinary tract infection . com...
[ "the aim of the present study was to evaluate the effect of sterilization with dry heat and steam on load - deflection characteristics of -ti wires , with different brands . . however , some manufacturers have used different methods to solve this problem , including incorporation of a titanium nitride and titanium ...	background : sterilization techniques could affect the characteristics of orthodontic wires . the aim of the present study was to evaluate the effect of steam and dry heat sterilization techniques on load - deflection behavior of five types of -titanium alloy wires.materials and methods : the samples consisted of 30 st...
[ "we present a case in which sd - oct was used to diagnose an asymptomatic pituitary macroadenoma . most pituitary adenomas are clinically inactive . in patients with long - standing compression of the optic chiasm , ganglion cells may undergo axonal degeneration . spectral domain optical coherence tomography ( sd -...	introductionmost pituitary adenomas are clinically inactive . in patients with long - standing compression of the optic chiasm , ganglion cells may undergo axonal degeneration . spectral domain optical coherence tomography ( sd - oct ) is able to identify retinal nerve fiber layer ( rnfl ) and ganglion cell loss in the...
[ "complications of this procedure are well reported ; however , to our knowledge no mention has occurred in the literature of a retained nephrostomy tube after pcnl . percutaneous nephrolithotomy ( pcnl ) is a widely accepted treatment for urinary calculi > 2 cm or resistant to other modalities . thus , we will pres...	percutaneous nephrolithotomy is a widely accepted treatment for urinary calculi , but it is not without complications . we present the case of a 76-year - old male with a retained council tip catheter after percutaneous nephrolithotomy . fluoroscopic guidance was used to perform percutaneous puncture of the catheter ba...
[ "radical prostatectomy ( rp ) is a common curative surgical treatment option in localized prostate cancer ( pca ) . , we investigated the histopathologic evaluation outcomes of anterior periprostatic fat ( appf ) tissues that were separately sent for pathologic evaluation in order to examine presence of lns and met...	introductionwe investigated whether anterior periprostatic fat ( appf ) tissue removed during robotic radical prostatectomy ( rarp ) contains any lymph nodes ( lns).material and methodsappf tissues removed during rarp in 129 patients were evaluated histopathologically . correlation with postoperative pathologic stage w...
[ "this study reviews previous parasite prevalence reports from american marten in north america , presents data from the parasitological examination of live - trapped american marten in michigan , and identifies a possible association between hookworm infection and anaemia in affected american marten . the aim of th...	the american marten ( martes americana ) was reintroduced to both the upper ( up ) and northern lower peninsula ( nlp ) of michigan during the 20th century . this is the first report of endoparasites of american marten from the nlp . faeces from live - trapped american marten were examined for the presence of parasitic...
[ "there are currently insufficient studies examining the effects of osteoarthritis on the frp \n of the erector spinae and on how the frp of the erector spinae observed in young adults is \n different from that of the elderly in whom osteoarthritis has occurred . therefore , the \n present study compared the frps of...	[ purpose ] this study investigated the flexion - relaxation phenomenon of the erector spinae in elderly women with chronic knee osteoarthritis and determined whether the flexion - relaxation phenomenon can be used as a pain evaluation tool in such cases . [ subjects and methods ] seventeen elderly females with c...
[ "though some data suggests metformin is safe in the setting of chronic kidney disease , the use of metformin in kidney transplant patients is still quite controversial due to the concern about lactic acidosis and lack of data regarding metformin use in this patient population [ 911 ] . however , evidence supporting...	new - onset diabetes after transplantation ( nodat ) is a common comorbidity after renal transplantation . though metformin is the first - line agent for the treatment of type 2 diabetes , in renal transplant recipients , metformin is frequently avoided due to concerns about renal dysfunction and risk for lactic acidos...
[ "although cm remains the most common cause of adult meningitis in the overall population in sub - saharan africa , there are only a few recognized , reported cases of gastrointestinal ( gi ) involvement with cryptococcus in the literature . substantial improvement in survival of people living with hiv has been obse...	the introduction of antiretroviral therapy ( art ) may lead to unusual paradoxical and unmasking presentations of opportunistic infections . intra - abdominal cryptococcosis is a rare manifestation of cryptococcus . we present the case of an hiv - infected patient on art , with a history of cryptococcal meningitis who ...
[ "the present study was conducted to know the prevalence , etiology and common clinical presentations of dermatophytosis involving skin and hair . dermatophytic infections are of major importance , as they are widespread and cause discomfort . reactions to dermatophyte infection may range from mild to severe . these...	introduction : dermatophytic infections are commonly encountered a problem and constitute more than 50% of cases in dermatology outpatient departments . diagnosis of these infections requires the proper use of laboratory methods.objectives:this study was conducted to know the etiology of dermatophytosis in patients att...
[ "the esr results clearly identify the c3 formation \n in one - electron oxidized gemcitabine and the production of c2 \n in one - electron oxidized mefdc . these calculations show \n that in the case of one - electron oxidized mefdc , the lowest energy \n path is the rapid formation of c2 from c3 \n via f loss . th...	gemcitabine is a modified cytidine analog having two fluorine atoms at the 2-position of the ribose ring . it has been proposed that gemcitabine inhibits rnr activity by producing a c3 intermediate via direct h3-atom abstraction followed by loss of hf to yield a c2 with 3-keto moiety . direct detection of c...
[ "the present study reports our intermediate experience in men who underwent implantation of adjustable perineal male sling using a tissue expander for ppi . it has a significant impact on the patient s quality of life ( 1 ) . mild degrees of ppi in the early postoperative period may be improved by pelvic muscle exe...	purpose to report our intermediate experience in treating patients with severe incontinence using an adjustable perineal male sling with a tissue expander.materials and methods an adjustable male sling procedure was performed on 21 patients with severe incontinence . the underlying etiology of urinary incontinence was ...
[ "we aimed to study the reliability and validity of the turkish version of the first by \n correlating this tool with the acr 2013altcr and the hospital anxiety and depression scale \n ( hads ) . fibromyalgia syndrome ( fms ) is a prevalent chronic pain condition among middle - aged females \n and is characterized b...	[ purpose ] an easy - to - use , psychometrically validated screening tool for fibromyalgia is needed . this study aims to evaluate the reliability and validity of the turkish version of the fibromyalgia rapid screening tool by correlating it with 2013 american college of rheumatology alternative diagnostic crite...
[ "based on this premise , this study was designed to examine the students possible role in changing their own negative practices , by first assessing their perceptions of the obstacles to positive dietary practices and increased physical activity . overweight and obesity are conditions that have been increasing in t...	this study was designed to assess students perceptions of the obstacles to positive dietary practices and increased physical activity and to solicit the students recommendations for addressing and possibly reducing the negative practices that are associated with the rise in obesity and the development of cardiovascular...
[ "this review focuses on the role of emps in angiogenesis , coagulation , and inflammation during age - related vascular diseases and the contribution of estrogen to these diseases . vascular diseases are among the most common causes of morbidity and mortality , and both number and severity of morbid vascular condit...	endothelial microparticles ( emps ) are complex vesicular structures that originate from plasma membranes of activated or apoptotic endothelial cells . emps play a significant role in vascular function by altering the processes of inflammation , coagulation , and angiogenesis , and they are key players in the pathogene...
[ ", we assessed the effects of eight weeks of three grams per day cinnamon supplementation ( cinnamomum zeylanicum ) on glycemic status , lipid profiles , blood pressure and body composition in type 2 diabetic patients . the present study investigated the proposed benefit of cinnamon use in patients with type 2 diab...	objective : type 2 diabetes is the most common metabolic disorder worldwide . traditional herbs and spices can be used to control blood glucose concentrations . the objective of this study was to evaluate the effects of the daily intake of three grams cinnamon over eight weeks on glycemic status , lipid profiles and bo...
[ "management of an unexpectedly difficult airway consists of laryngeal mask ventilation , gum - elastic bougie and video laryngoscopy - assisted intubation . . failed endotracheal intubation and inadequate ventilation with insufficient oxygenation may lead to serious complications , even death . gum - elastic bougie...	backgrounda critical aspect of safe general anesthesia is providing adequate ventilation and oxygenation . failed endotracheal intubation and inadequate ventilation with insufficient oxygenation may lead to serious complications , even death . anesthesiologists rarely encounter unexpected difficult airway problems in d...
[ "incidence ( cases per 1,000 admissions ) of human listeriosis and serotype distribution of all isolates , national taiwan university hospital , taipei , taiwan , 19962008 . all of the patients with listeriosis lived in northern taiwan , and no obvious geographic correlation was observed between listeriosis patient...	during 19962008 , a total of 48 patients with listeriosis were identified at a taiwan hospital . average annual incidence increased from 0.029 to 0.118 cases per 1,000 admissions before and after january 2005 . serotype 1/2b predominated ; serotype 4b emerged since 2004 . food monitoring and disease surveillance system...
[ "two of the three cats had undergone onychectomy several years before presentation . a permanent flexion of the proximal interphalangeal joint of one or more digits , associated with a difficult and painful extension of the proximal interphalangeal joint , previous anti - inflammatory administrations were unable to...	case series summarythree cats , siamese or siamese cross , were presented with a chronic thoracic limb weightbearing lameness . previous anti - inflammatory administrations were unable to improve lameness consistently in the three cats . two of the three cats had undergone onychectomy several years before presentation ...
[ "therefore , the aim of this study was to investigate the expression of the adiponectin gene by real - time pcr , to determine the concentrations of adiponectin protein in the porcine ovary ( corpora lutea , granulosa and theca interna cells ) and to compare gene and protein expression levels during different stage...	adiponectin is an adipose - secreted hormone that regulates energy homeostasis and is also involved in the control of the reproductive system . the goal of the present study was to investigate changes in adiponectin gene and protein expression in porcine ovarian structures during the oestrous cycle and to examine the e...
[ "molecular and morphological evidence together support the idea that the anterior end of the amphioxus nerve cord contains regions homologous with vertebrate forebrain and hindbrain 1,2 , though it is generally the ventral portion of these regions that are best represented 3 . the quintessential identifying feature...	the mhb ( midbrain - hindbrain boundary ) is a key organizing center in the vertebrate brain characterized by highly conserved patterns of gene expression . the evidence for an mhb homolog in protochordates is equivocal , the " neck " region immediately caudal to the sensory vesicle in ascidian larvae being the best ac...
[ "the patient was posted for partial nephrectomy with the provisional diagnosis of renal tuberculosis or renal infarction involving upper pole . he was put on cisplatin and sunitinib on the suspicion of primary lung tumour and showed no response . a seventy five year old libyan man was seen in the urology department...	a seventy five year old gentleman with the clinical diagnosis of renal tuberculosis was found to have renal squamous cell carcinoma . the clinical presentation and management are being discussed .
[ "the goal of this study was to investigate the chemical composition and in vitro antifungal and antibiofilm activities of essential oils of the leaves of m. piperita collected in the region of fars from iran . mentha piperita , ( family lamiaceae ) is a species found in iran and many parts of the world which has an...	variations in quantity and quality of essential oil ( eo ) from the aerial parts of cultivated mentha piperita were determined . the eo of air - dried sample was obtained by a hydrodistillation method and analyzed by a gas chromatography / mass spectrometry ( gc / ms ) . the antifungal activity of the eo was investigat...
[ "the hardware and software realization of the device is mainly based on a single triaxial accelerometer and gps / gsm module . the device uses an efficient fall detection algorithm with less resource and power consumption , which means that it is a proper design for outdoor application . mems ( microelectro mechani...	fall detection is a major challenge in the public healthcare domain , especially for the elderly as the decline of their physical fitness , and timely and reliable surveillance is necessary to mitigate the negative effects of falls . this paper develops a novel fall detection system based on a wearable device . the sys...
[ "one radiologist retrospectively reviewed the medical records of the patients who received tfesi using the conventional approach at our department during a 1-year period , from june 2003 to may 2004 . a successful outcome required a patient satisfaction score of 3 ( very good ) or 4 ( excellent ) , and a reduction ...	objectivethe present study was undertaken to evaluate the effectiveness of transforaminal epidural steroid injection ( tfesi ) with using a preganglionic approach for treating lumbar radiculopathy when the nerve root compression was located at the level of the supra - adjacent intervertebral disc.materials and methodst...
[ "although the rotation includes both \n photochemical and thermal steps \n that involve different parts of the motor , the structural evolution \n is largely governed by the excited - state properties of the central \n c = c group , which , in turn , are dictated by the potential energy \n surfaces of the excited s...	controlling the excited - state properties of light driven molecular machines is crucial to achieving high efficiency and directed functionality . a key challenge in achieving control lies in unravelling the complex photodynamics and especially in identifying the role played by dark states . here we use the s...
[ "the objective of our study was to determine the impact of knee position and quadriceps contraction on patellofemoral indices measured on mri . the patellofemoral joint is one of the most common sources of knee pain in younger people . differences in the morphology of the patellofemoral joint have been shown to be ...	purposethe purpose of this study was to investigate the impact of varying knee flexion and quadriceps activity on patellofemoral indices measured on magnetic resonance imaging ( mri).materials and methodsmri of the knee was performed in 20 patients for indications other than patellar or patellofemoral pathology . axial...
[ "the elastic fracture theory is a suitable tool to compute the mechanical behaviour in case of coatings , composites , and welded structures . , the interface of solid materials covers a sinusoidal surface layer due to a rotation of successive constraints in tensile and compression stress in the structure . a robus...	the behaviour of materials is governed by the surrounding environment . the contact area between the material and the surrounding environment is the likely spot where different forms of degradation , particularly rust , may be generated . a rust prevention treatment , like bluing , inhibitors , humidity control , coati...
[ "our results establish that targeting mir-134 offers broad anticonvulsant and possibly disease - modifying effects in experimental epilepsy , which may encourage pre - clinical development of ant-134 as a treatment for epilepsy . proof of seizure - suppressive effects of ant-134 in a non - status epilepticus model ...	current anti - epileptic drugs ( aeds ) act on a limited set of neuronal targets , are ineffective in a third of patients with epilepsy , and do not show disease - modifying properties . micrornas are small noncoding rnas that regulate levels of proteins by post - transcriptional control of mrna stability and translat...
[ ", we sought to estimate the association between analgesic use and headache among adults in a large sample of the jordanian population in relation to age , gender and headache frequency . most of the recurrent headache cases are due to benign chronic primary headache disorders , such as tension headache and migrain...	here , we investigated the prevalence of headache among adults in jordan . the study was conducted from january 2007 to november 2008 . a sample of 4,836 participants were permitted to complete a self - conducted screening questionnaire . as much as 82.3% of participants complained from headache at least once per year ...
[ "she has remained disease - free for six years postoperatively , with regular coumadin anticoagulation therapy due to the presence of the prosthetic aortic and mitral valves . based on this finding , we diagnosed the patient with a pseudoaneurysm of the left ventricle , and surgical treatment was planned . ten year...	we present a case of left ventricular pseudoaneurysm , which is a very rare and fatal complication of cardiac procedures such as mitral valve replacement . a 55-year - old woman presented to the department of thoracic and cardiovascular surgery at hanyang university seoul hospital with chest pain . ten years prior , th...
[ "posterior urethral valve ( puv ) is the most common cause of congenital bladder outlet obstruction in boys and causes renal failure in 25% to 30% of cases before adolescence . puv is associated with considerable morbidity , including urinary tract infection ( uti ) , chronic renal failure , urinary incontinence , ...	purposeto find patients at high risk of obstructive remnant leaflets after valve ablation among boys with posterior urethral valve ( puv ) , we evaluated any possible relationship between preoperative findings in our patients and residual obstructive leaflets after valve ablation.materials and methodswe retrospectively...
[ "the objective of this study was to determine whether calculus , hypocalcification , and stain are confounding factors affecting wsl detection with optical coherence tomography and polarized raman spectroscopy . clearly , a new technology is needed that will not be affected by factors in the oral environment . a ne...	optical coherence tomography ( oct ) and polarized raman spectroscopy ( prs ) have been shown as useful methods for distinguishing sound enamel from carious lesions ex vivo . however , factors in the oral environment such as calculus , hypocalcification , and stain could lead to false - positive results . oct and prs w...
[ "the histologic characteristics of i - hca are presence of inflammatory infiltrate , marked sinusoidal dilatation , and thick - walled arteries.8 steatosis may be present in patients with i - hca but is not as extensive as that in patients with h - hca.8 diffuse or focal cytoplasmic immunostaining for saa was inter...	backgroundhepatocellular adenoma ( hca ) is a rare benign tumor of the liver . a subtype classification of hca ( hepatocyte nuclear factor 1 [ hnf1]-mutated , -catenin - mutated hca , inflammatory hca , and unclassified hca ) has recently been established based on a single institutional review of a hca series by the bo...
[ "this article aims to review the use of pet imaging to promote the understanding of activated microglia in neurodegenerative disease . microglia account for approximately 10% of the adult brain cell population and represent the first and main form of immune defense in the central nervous system ( cns ; lawson et al...	microglia constitute the main immune defense in the central nervous system . in response to neuronal injury , microglia become activated , acquire phagocytic properties , and release a wide range of pro - inflammatory mediators that are essential for the annihilation of the neuronal insult . although the role of microg...
[ "to this aim we evaluated also conventional arthritic parameters ( hpv , arthritic score , body weight change , and weight of the liver ) along with changes in plasmatic levels of il-1 and crp and the activity of 12/15-lox in the liver . yet application of a combination therapy of mtx with other potential immunomod...	rheumatoid arthritis ( ra ) is a chronic inflammatory disease , leading to progressive destruction of joints and extra - articular tissues , including organs such as liver and spleen . the purpose of this study was to compare the effects of a potential immunomodulator , natural polyphenol n - feruloylserotonin ( n - f-...
[ "they advised future studies to investigate the direct relationship between psychological health problems and internet dependency ( 8) . in this study we tried to investigate the prevalence of internet , computer games , and dvd and video addiction among high school students in southern iran , shiraz , and its rela...	objective : the objective of this study was to assess the prevalence of addiction to the internet , computer games , dvd , and video and its relationship to anxiety and depression in a sample of iranian high school students . methods : in this cross - sectional study 1020 high school students ( males and females ) were...
[ "the samples are from a cohort of 16 pregnant women , with each subject sampled a median of 18 times . because this represents a significant increase in the number of tests per subject compared to previous studies , we applied the multiplex array approach to evaluate the changes in 42 cytokines in rich detail durin...	several recent studies have shown differences in the maternal immune milieu at different phases of pregnancy , but most studies have been cross - sectional or of relatively few time points . levels of 42 cytokines were determined using a multiplex bead - based assay on archived serum from a cohort of pregnant women ( n...
[ "however , data supporting this hypothesis remain controversial \n . clinical features of this disease include the following nonspecific symptoms : cough , dyspnea , erythema nodosum , febrile arthritis , uveitis , and parotitis sarcoidosis - related granulomatous reaction of the immune system could be attributed t...	sarcoidosis is a benign systematic granulomatous disorder of unknown etiology and is associated with various malignancies . however , granulomatous and metastatic lymph node lesions are difficult to distinguish even when using precise and modern diagnostic methods , such as positron emission tomography . thus , histolo...
[ "formation of the plateau at 5 years was characterized by the loss of the overlying rpe causing marked thinning of the hyperreflective rpe - basal lamina complex now reduced to just blamd , compared with at 4 years . at 7 years amd eyes were identified through an ex vivo imaging screen of eyes accessioned for resea...	purposehistologic details of progression routes to geographic atrophy ( ga ) in amd are becoming available through optical coherence tomography ( oct ) . we studied the origins and evolution of an oct signature called plateau in eyes with ga and suggested a histologic correlate.methodsserial eye - tracked oct scans and...
[ "pulmonary arterial endarteritis is a rare event , even in patients with congenital heart disease ( chd ) . endocarditis of the right side of the heart is uncommon by virtue of the low hemodynamic pressure and lack of isolated or significant right - sided valvular deformities . further , a combination of pulmonary ...	endocarditis of the right side of the heart is otherwise uncommon in children . pulmonary endarteritis as a complication of congenital heart disease is even rarer . herein , we report the case of pulmonary endarteritis with a 7 mm 5 mm vegetation , involving the main pulmonary artery in a 4-year - old male child , with...

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