metadata
license: cc0-1.0
language:
- en
tags:
- neuroinflammation
- depression
- biomarkers
- IL-6
- TNF-alpha
- CRP
- mental-health
- psychiatry
pretty_name: Neuroinflammation Biomarkers in Depression (2020-2024)
doi: 10.7910/DVN/QBQXKL
Neuroinflammation Biomarkers in Depression (2020-2024)
Author: Juan Moises de la Serna | ORCID: 0000-0002-8401-8018
Full dataset: Harvard Dataverse doi.org/10.7910/DVN/QBQXKL
Description
Global meta-analysis of neuroinflammation biomarkers (IL-6, TNF-α, CRP, IL-1β) in depression (MDD), bipolar disorder (BD), and healthy controls. 147 studies, 15,000+ participants, 2020–2024.
| Biomarker | MDD | HC | Ratio |
|---|---|---|---|
| IL-6 | 7.8 pg/mL | 2.4 pg/mL | 3.25× |
| TNF-α | 18.5 pg/mL | 8.2 pg/mL | 2.26× |
| CRP | 4.2 mg/L | 1.2 mg/L | 3.50× |
Quick Start
# pip install neuroinflammation-biomarkers-depression
from neuroinflammation_biomarkers import load_dataset, get_biomarker_summary
df = load_dataset()
summary = get_biomarker_summary()
Citation
de la Serna, J.M. (2024). Neuroinflammation Biomarkers in Depression. Harvard Dataverse. https://doi.org/10.7910/DVN/QBQXKL