messages listlengths 2 2 | source stringclasses 2
values | protein_id stringlengths 6 11 ⌀ |
|---|---|---|
[
{
"role": "user",
"content": "Tapasin\nWhat is the consequence of the downregulation of Tapasin molecules?"
},
{
"role": "assistant",
"content": "The downregulation of Tapasin molecules blocks the transportation of TAP-bound peptides to the ER to bind SLA I molecules."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Glutathione-specific gamma-glutamylcyclotransferase 1\nHow does the protein contribute to the process of hemoglobin biosynthesis?"
},
{
"role": "assistant",
"content": "The protein plays a role in blocking protein synthesis necessary for hemoglobin biosynthesis."
... | Protein2Text-QA | null |
[
{
"role": "user",
"content": "protein disulfide-isomerase\nIs the protein typically found inside the cell or on its surface?"
},
{
"role": "assistant",
"content": "The protein is found in extracellular vesicles, which are outside the cell."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Myelin P2 protein\nWhat are the known genetic causes of Charcot-Marie-Tooth disease type 1?"
},
{
"role": "assistant",
"content": "There are five known genetic causes."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Latent-transforming growth factor beta-binding protein 4\nWhat type of cells does this protein interact with?"
},
{
"role": "assistant",
"content": "It interacts with innate immune cells, such as tumor-associated macrophages."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Transcription factor AP-2-beta\nCan you describe its relationship with clear cell renal cell carcinoma (ccRCC)?"
},
{
"role": "assistant",
"content": "It may function as an oncogene in ccRCC."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Interleukin-17 receptor E\nWhat happens to wound closure in mice that are deficient in this protein?"
},
{
"role": "assistant",
"content": "Wound closure is significantly delayed"
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Fibroblast growth factor 5\nWhat is the relationship between this protein and inflammatory factors?"
},
{
"role": "assistant",
"content": "There is a significant causal relationship between this protein and inflammatory factors, with the protein being one of the 3 i... | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Dysbindin\nWhat is the role of this protein in the brain?"
},
{
"role": "assistant",
"content": "This protein is involved in the regulation of appetitive motivation, which is the desire for rewards or pleasure."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Aminopeptidase\nWhat is the relationship between the protein's activity and viscosity?"
},
{
"role": "assistant",
"content": "Its catalytic rate is highly dependent on viscosity."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Helicase POLQ-like\nWhat are the clinically relevant roles of the protein?"
},
{
"role": "assistant",
"content": "Its critical roles in the regulation of various DNA processes and participation in tumorigenesis are clinically relevant."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Transmembrane protease serine 6\nCan you tell me about the relationship between the protein and serum ferritin levels?"
},
{
"role": "assistant",
"content": "Carriers of the BTBD9 C/T and TT genotypes have lower serum ferritin values, but those with the protein's A/... | Protein2Text-QA | null |
[
{
"role": "user",
"content": "P2Y purinoceptor 1\nWhat is the primary function of this protein?"
},
{
"role": "assistant",
"content": "It acts as a G protein–coupled receptor, which is involved in cell signaling."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Serine/arginine-rich splicing factor 5\nIs the expression of this protein different in individuals with a certain disease?"
},
{
"role": "assistant",
"content": "Yes, its expression is different in individuals with bipolar disorder."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Myeloid-derived growth factor\nIs there a specific signaling pathway involved in the protein's protective effect on non-alcoholic fatty liver disease?"
},
{
"role": "assistant",
"content": "Yes, IKKβ/NF-κB signaling is involved."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Rab-interacting lysosomal protein\nWhat is the correlation between the protein and the development of endometrial carcinoma?"
},
{
"role": "assistant",
"content": "According to the research, Mendelian randomization analysis revealed a negative correlation between th... | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Synaptotagmin-14\nWhat was the specific polymorphism found in the protein that was associated with polyphasia?"
},
{
"role": "assistant",
"content": "The polymorphism p.Glu270del was identified in JME patients and their relatives presenting polyphasia."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Pyruvate kinase\nWhat role does this protein play in maintaining cell integrity?"
},
{
"role": "assistant",
"content": "It improves cell integrity, as seen in red blood cells with sickle cell disease."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Serine/threonine-protein kinase ULK1\nWhat type of kinase is the protein?"
},
{
"role": "assistant",
"content": "It is a serine/threonine-protein kinase."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Natural cytotoxicity triggering receptor 3\nCan the function of this protein be affected by other proteins?"
},
{
"role": "assistant",
"content": "Yes, the function of this protein can be influenced by the presence of other proteins, such as NKG2D."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Persephin\nHow does this protein's effect lead to an increase in dopaminergic neurons?"
},
{
"role": "assistant",
"content": "By upregulating tyrosine hydroxylase expression."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Sulfhydryl oxidase 2\nWhat happened to the formation of the corpus luteum in female Qsox2 knockout mice?"
},
{
"role": "assistant",
"content": "a drastic decrease"
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Cholesteryl ester transfer protein\nWhat is the primary function of this protein?"
},
{
"role": "assistant",
"content": "This protein is involved in the transfer of cholesteryl esters between lipoproteins."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Poly(A) polymerase beta\nWhat is the general function of the protein in the cell?"
},
{
"role": "assistant",
"content": "The protein plays a crucial role in the base excision repair pathway, helping to repair damaged DNA."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Catenin delta-1\nDoes the protein play a role in the migration and invasion of HCC cell lines?"
},
{
"role": "assistant",
"content": "Silencing it inhibited the migration and invasion of HCC cell lines."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Caspase-3\nDoes this protein have a specific location within the cell where it is active?"
},
{
"role": "assistant",
"content": "Yes, this protein is primarily found in the cytosol of cells, where it can interact with other proteins and enzymes."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Thyrotroph embryonic factor\nHow is the expression level of the protein related to PTSS severity?"
},
{
"role": "assistant",
"content": "The expression level of the protein is positively associated with PTSS severity."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Caspase-3\nCan the activation of Caspase-3 lead to cell death?"
},
{
"role": "assistant",
"content": "Yes, Caspase-3 activation is associated with TNFα-mediated apoptosis."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Transcription factor AP-2 gamma\nWhat happens to the protein's expression level in bladder cancer tissues compared to adjacent normal tissues?"
},
{
"role": "assistant",
"content": "The protein's expression level is significantly upregulated in most bladder cancer t... | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Homeobox protein Hox-A5\nWhat is the relationship between the protein and oxidative stress?"
},
{
"role": "assistant",
"content": "The protein helps to reduce oxidative stress, which is associated with cell death."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "GTP-binding nuclear protein Ran\nDoes this protein play a role in protein expression?"
},
{
"role": "assistant",
"content": "Yes, this protein's expression is affected by the treatment with ZAD-1 and andrographolide."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Galectin-12\nWhat is the primary role of the protein in fat development?"
},
{
"role": "assistant",
"content": "The protein acts as an important regulator of fat deposition."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "TYRO protein tyrosine kinase-binding protein\nIs the protein involved in immune response?"
},
{
"role": "assistant",
"content": "Yes, it is related to biological processes and metabolic pathways related to immune response."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Vexin\nWhat happens to muscle cell proliferation when the protein is overexpressed?"
},
{
"role": "assistant",
"content": "It is inhibited."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Spartin\nCan a protein from a different species also localize to lipid droplets in plant cells?"
},
{
"role": "assistant",
"content": "Yes, a protein from a different species, such as spartin from humans, can also localize to lipid droplets in plant cells."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "G-protein coupled receptor 3\nIs this protein constitutively active?"
},
{
"role": "assistant",
"content": "Yes, it is a constitutively active receptor."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Transcription factor 7-like 2\nHow does the expression of this protein differ between old and young patients with type 2 diabetes?"
},
{
"role": "assistant",
"content": "The expression of this protein is significantly higher in old patients compared to young patient... | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Legumain\nWhat type of cells internalize and activate this protein?"
},
{
"role": "assistant",
"content": "Osteogenic cells do."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Phosphoethanolamine/phosphocholine phosphatase\nWhat is the primary focus of the current knowledge about this protein?"
},
{
"role": "assistant",
"content": "The primary focus is on its role in regulating energy metabolism."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "G1/S-specific cyclin-D2\nCan the protein be found in stress granules?"
},
{
"role": "assistant",
"content": "Yes, the protein was found to be associated with stress granules, which suggests a possible role in the origin of Rosenthal fibers."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Muscarinic acetylcholine receptor M3\nWhat type of receptor is this protein?"
},
{
"role": "assistant",
"content": "It is a G-protein-coupled receptor."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "JTB protein\nWhat pathways is the protein associated with?"
},
{
"role": "assistant",
"content": "The protein is associated with mitotic spindle assembly, estrogen response early and late, epithelial-to-mesenchymal transition (EMT), and other pathways."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Sodium/glucose cotransporter 1\nWhat is the role of this protein in intestinal cells?"
},
{
"role": "assistant",
"content": "It is critical for glucose uptake in intestinal cells."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Roundabout homolog 2\nDoes this protein have a role in cellular processes that are closely related to vascular responses?"
},
{
"role": "assistant",
"content": "Yes, this protein is implicated in pathways involved in vascular or platelet derived growth factor signal... | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Tektin-2\nIs this protein a structural component of cells?"
},
{
"role": "assistant",
"content": "Yes, it is likely a structural component of cells, given its involvement in sperm development and function."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Cytidine deaminase\nWhat is the role of this protein in the formation of translocations associated with a subtype of acute lymphoblastic leukemia (ALL)?"
},
{
"role": "assistant",
"content": "It is involved in the process."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "DNA nucleotidylexotransferase\nWhat is the primary function of this protein?"
},
{
"role": "assistant",
"content": "This protein is involved in DNA replication, specifically adding nucleotides to the 3' end of a DNA strand."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Pentraxin-related protein PTX3\nIs this protein involved in cardiovascular disease?"
},
{
"role": "assistant",
"content": "Yes, it is one of the biomarkers of cardiovascular disease measured in this study."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "DNA (cytosine-5)-methyltransferase 3B\nWhat is the primary function of the protein in eukaryotic cells?"
},
{
"role": "assistant",
"content": "Maintaining the DNA methylation pattern."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Tumor necrosis factor receptor superfamily member 13B\nWhat is the primary function of this protein?"
},
{
"role": "assistant",
"content": "The primary function of this protein is to regulate the immune system."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Immunoglobulin lambda-like polypeptide 1\nWhat is the general function of the protein in an organism?"
},
{
"role": "assistant",
"content": "The protein is involved in B lymphocyte development and may play essential roles in the development of the bursa of Fabricius... | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Galectin-12\nDoes the protein interact with multiple signaling pathways?"
},
{
"role": "assistant",
"content": "Yes, the protein is associated with multiple signaling pathways."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Diacylglycerol kinase iota\nWhat is the role of the protein in cancer?"
},
{
"role": "assistant",
"content": "The protein might be a promising prognostic molecular marker in patients with THCA."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Serine hydrolase RBBP9\nWas this discovery made in collaboration with other researchers?"
},
{
"role": "assistant",
"content": "Yes, it was conducted in collaboration with the Molecular Libraries Screening Center Network (MLSCN)."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Ras-related protein Rab-22A\nIs this protein typically found in normal tissues?"
},
{
"role": "assistant",
"content": "No, the expression of this protein was found to be decreased in normal tissues compared to non-small cell lung cancer tissues."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "small monomeric GTPase\nHow is the function of this protein related to the growth of muscles during adult myogenesis?"
},
{
"role": "assistant",
"content": "It is essential for growth of these muscles during the later half of adult myogenesis."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Complement factor I\nWhat types of assays are used to measure the protein's function?"
},
{
"role": "assistant",
"content": "C3b and C4b fluid phase cleavage assays and a novel bead-based functional assay (BBFA) of C3b cleavage."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Ephrin-A2\nWhat happens to the expression of this protein when a tumor becomes resistant to bevacizumab treatment?"
},
{
"role": "assistant",
"content": "The expression of this protein increases when a tumor becomes resistant to bevacizumab treatment."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Chromobox protein homolog 8\nWhat kind of processes does this protein participate in?"
},
{
"role": "assistant",
"content": "This protein is involved in various biological processes such as cell differentiation, aging, and cell cycle progression."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Tumor protein p53-inducible nuclear protein 2\nHow does the protein affect reactive oxygen species production in muscles?"
},
{
"role": "assistant",
"content": "Reducing ROS production is one of the benefits of activating autophagy with this protein."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Calcineurin subunit B type 1\nWhat is the general function of this protein?"
},
{
"role": "assistant",
"content": "This protein plays a role in various cellular processes, including the regulation of the immune system and cellular signaling."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Zinc-alpha-2-glycoprotein\nWhat happens to the level of this protein in prediabetic conditions?"
},
{
"role": "assistant",
"content": "It decreases in prediabetic conditions."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Regulator of G-protein signaling 2\nWhat is the function of this protein in the heart?"
},
{
"role": "assistant",
"content": "This protein is a Gq inhibitor, meaning it plays a role in regulating the activity of Gq proteins, which are involved in cell growth and sig... | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Zinc finger protein 750\nCan the protein's function be influenced by external factors, such as chemical manipulation?"
},
{
"role": "assistant",
"content": "Yes, its function can be influenced by chemical manipulation, such as all-trans retinoic acid."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Mitochondrial-derived peptide MOTS-c\nWhat is the primary function of this protein in the body?"
},
{
"role": "assistant",
"content": "The primary function of this protein is to promote cold adaptation and improve metabolic function."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Prelamin-A/C\nCan a protein like this one be used as a potential therapeutic target for a disease like canine diabetes?"
},
{
"role": "assistant",
"content": "While not explicitly stated, proteins like this one may potentially be used as a therapeutic target in the ... | Protein2Text-QA | null |
[
{
"role": "user",
"content": "D-3-phosphoglycerate dehydrogenase\nIs this protein directly involved in protecting the photosynthetic machinery?"
},
{
"role": "assistant",
"content": "This protein is not directly involved in protecting the photosynthetic machinery, but its loss in combination wit... | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Excitatory amino acid transporter 1\nCan the protein's reduction be reversed?"
},
{
"role": "assistant",
"content": "Yes, with the administration of arundic acid, which prevents the loss of motor neurons and preserves motor functions."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Cortactin-binding protein 2\nCan the defects caused by knocking down the protein be rescued by overexpressing cortactin?"
},
{
"role": "assistant",
"content": "Yes, the defects caused by knocking down the protein were rescued by overexpressing cortactin."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Transcription factor AP-2-beta\nIs this protein involved in inflammation?"
},
{
"role": "assistant",
"content": "It is associated with genes involved in inflammation."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "G-protein coupled estrogen receptor 1\nWhat effect does the protein have on lipid accumulation in the liver?"
},
{
"role": "assistant",
"content": "The protein helps to mitigate lipid accumulation in the liver."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "DNA nucleotidylexotransferase\nWhat percentage of TdT+ bone marrow cells from normal and athymic mice express Lyt antigens after treatment?"
},
{
"role": "assistant",
"content": "More than 80%."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Cytochrome P450 26A1\nHow does the protein affect the subsets of NK cells?"
},
{
"role": "assistant",
"content": "It affects the subsets of NK cells, specifically, the two most variable subpopulations after its knockdown were trNKp and trNK2 cells."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Cysteine-rich secretory protein 3\nDoes the protein bind to MSP through a covalent or non-covalent interaction?"
},
{
"role": "assistant",
"content": "It binds through a non-covalent interaction."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Rhodopsin\nHow is this protein related to insecticide resistance?"
},
{
"role": "assistant",
"content": "It is overexpressed in resistant strains and is thought to act as a trans-regulatory factor for P450-mediated resistance"
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Fibroblast growth factor 14\nCan you tell me about its role in a particular disease or condition?"
},
{
"role": "assistant",
"content": "It may represent a therapeutic target for mitigating consequences of TNF-mediated neuroinflammation."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Phosducin\nIs the protein's interaction with the substrate dependent on other factors?"
},
{
"role": "assistant",
"content": "Yes, the protein's interaction with the substrate is part of a larger process that involves TRiC subunits and other cochaperones."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "G-protein coupled estrogen receptor 1\nWhat is the importance of understanding this protein's mechanism of action?"
},
{
"role": "assistant",
"content": "It is of high importance due to the detrimental effects experienced during its absence with aging and the increa... | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Melanopsin\nWhat is the protein responsible for in terms of labeling cells?"
},
{
"role": "assistant",
"content": "The protein is responsible for labeling ipRGCs with minimal recombination escape."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Protein smoothened\nWhere is GRK2 phosphorylated of this protein critical?"
},
{
"role": "assistant",
"content": "GRK2 phosphorylation of this protein is critical for initiating events for the intracellular steps in Hh signaling."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Guanylate-binding protein 1\nHow does the protein oligomerize?"
},
{
"role": "assistant",
"content": "A surface-exposed helix in the large GTPase domain contributes to the oligomerization interface."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Trace amine-associated receptor 1\nHow does blocking dopamine receptors affect this protein's effect on REM sleep?"
},
{
"role": "assistant",
"content": "Blocking dopamine receptors does not affect this protein's suppression of REM sleep."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Polyprotein\nCan you describe the components of this structural polyprotein?"
},
{
"role": "assistant",
"content": "The structural polyprotein consists of multiple subunits, including capsid, envelope 3, envelope 2, 6 K, and envelope 1."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Cyclin-dependent kinase 2\nWhat is the role of the protein in cell division?"
},
{
"role": "assistant",
"content": "The protein plays a role in regulating cell-cycle genes."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Neurotrophin-3\nWhat is the result of increased expression of this protein on synapse density?"
},
{
"role": "assistant",
"content": "It increases synapse density."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Transmembrane protein 45A\nWhat is the function of the protein in relation to tumours?"
},
{
"role": "assistant",
"content": "It is identified as a diagnostic biomarker for osteosarcoma."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Transcription elongation factor SPT6\nWhere is the protein enriched in a specific type of cell?"
},
{
"role": "assistant",
"content": "It is enriched at super-enhancers."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Metabotropic glutamate receptor 8\nHow is the protein's function related to neurodevelopmental disorders?"
},
{
"role": "assistant",
"content": "Disturbed glutamate signaling during development might partly cause neurodevelopmental disorders."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Ras and Rab interactor 3\nCan dysregulation of this protein contribute to disease conditions?"
},
{
"role": "assistant",
"content": "Yes, increasing evidence suggests that dysregulation of this protein"
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "TNF receptor-associated factor 5\nHow does the protein differ between patients in the low-risk and high-risk groups?"
},
{
"role": "assistant",
"content": "Patients in the low-risk group exhibited high sensitivity toward immunotherapy and chemotherapy, whereas those... | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Cytochrome c\nWhat are some of the key functions of protein in cellular processes?"
},
{
"role": "assistant",
"content": "The protein is involved in regulating mitochondrial dynamics, including electron transport chain function and the release of cytochrome c."
}
... | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Advillin\nIs the protein's function altered in mice that are obese due to global deletion of another protein?"
},
{
"role": "assistant",
"content": "Yes, the protein"
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Cold-inducible RNA-binding protein\nHow does this protein undergo changes in response to environmental stressors?"
},
{
"role": "assistant",
"content": "This protein itself also undergoes conformational changes in response to diverse environmental stress."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Ubiquitin-conjugating enzyme E2 C\nIs this protein a potential target for treating lymph node-metastatic bladder cancer?"
},
{
"role": "assistant",
"content": "Yes, it is identified as a promising target for treating lymph node-metastatic bladder cancer."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Enhancer of rudimentary homolog\nIs the protein involved in cell cycle regulation?"
},
{
"role": "assistant",
"content": "yes."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "RNA ligase 1\nWhat is the impact of this protein on the spatial organization of exopolysaccharides in biofilms?"
},
{
"role": "assistant",
"content": "This protein impairs the three-dimensional biofilm architecture and affects the spatial organization of exopolysacc... | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Coronin-2B\nWhat is the impact of this protein's malfunction on cortical development?"
},
{
"role": "assistant",
"content": "It results in increased seizure susceptibility, suggesting the malfunction of cortical development."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "inositol-3-phosphate synthase\nWhat is the primary function of the protein?"
},
{
"role": "assistant",
"content": "The primary function of the protein is likely related to the synthesis of inositol-3-phosphate, which is a crucial component in various cellular proces... | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Ankyrin-1\nIs the protein activated by a specific agonist?"
},
{
"role": "assistant",
"content": "Yes, it is activated by cinnamaldehyde."
}
] | Protein2Text-QA | null |
[
{
"role": "user",
"content": "Persephin\nWhat type of biological molecule is the protein?"
},
{
"role": "assistant",
"content": "A ligand, which is a type of signaling molecule that binds to receptors."
}
] | Protein2Text-QA | null |
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