conversations listlengths 2 2 |
|---|
[
{
"from": "human",
"value": "Question: Is obesity associated with increased postoperative complications after operative management of proximal humerus fractures?\nContext: {'contexts': ['Obesity has become a significant public health concern in the United States. The goal of this study was to assess the eff... |
[
{
"from": "human",
"value": "Question: Is radiofrequency ablation a thyroid function-preserving treatment for patients with bilateral benign thyroid nodules?\nContext: {'contexts': ['To evaluate the efficacy and safety of radiofrequency (RF) ablation for treatment of bilateral thyroid nodules as well as pre... |
[
{
"from": "human",
"value": "Question: Does silence of MCL-1 upstream signaling by shRNA abrogate multiple myeloma growth?\nContext: {'contexts': ['Multiple myeloma (MM) is an incurable B-cell cancer with accumulated clonal abnormal plasma cells in bone marrow of patients. MCL-1 (myeloid cell leukemia seque... |
[
{
"from": "human",
"value": "Question: Does pulse oximetry measure a lower heart rate at birth compared with electrocardiography?\nContext: {'contexts': ['To examine the effect of time after birth on heart rate (HR) measured by pulse oximetry (PO) (HRPO) and electrocardiography (ECG) (HRECG).', 'HRECG and H... |
[
{
"from": "human",
"value": "Question: Does brivaracetam differentially affect voltage-gated sodium currents without impairing sustained repetitive firing in neurons?\nContext: {'contexts': ['Brivaracetam (BRV) is an antiepileptic drug in Phase III clinical development. BRV binds to synaptic vesicle 2A (SV2... |
[
{
"from": "human",
"value": "Question: Does ascorbic Acid ameliorate nicotine exposure induced impaired spatial memory performances in rats?\nContext: {'contexts': ['The long lasting behavioural and cognitive impairments in offspring prenatally exposed to nicotine have been confirmed in animal models. In th... |
[
{
"from": "human",
"value": "Question: Are glutathione s-transferase m1 and t1 gene polymorphisms associated with increased risk of gestational diabetes mellitus development?\nContext: {'contexts': ['The aim of this study was to investigate whether the glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) gen... |
[
{
"from": "human",
"value": "Question: Does heterologous expression of mutated HLA-G1 reduce alloreactivity of human dermal fibroblasts?\nContext: {'contexts': ['To engineer a stable HLA-G molecule and evaluate its immunomodulatory properties in transgenic human dermal fibroblasts (HDFs).', \"A mutated HLA-... |
[
{
"from": "human",
"value": "Question: Does a cluster-randomized trial show telephone peer coaching for parents reduces children 's asthma morbidity?\nContext: {'contexts': [\"Childhood asthma morbidity remains significant, especially in low-income children. Most often, asthma management is provided by the ... |
[
{
"from": "human",
"value": "Question: Is lipoprotein internalisation induced by oncogenic AMPK activation essential to maintain glioblastoma cell growth?\nContext: {'contexts': ['Metabolic adaptations are essential during tumour growth to maintain the high proliferation levels exhibited by cancer cells. In... |
[
{
"from": "human",
"value": "Question: Are tools for assessing the content of guidelines needed to enable their effective use -- a systematic comparison?\nContext: {'contexts': ['To ensure that clinical practice guidelines (CPGs) form a sound basis for decision-making in health care, it is necessary to be a... |
[
{
"from": "human",
"value": "Question: Is high blood eosinophil count a risk factor for future asthma exacerbations in adult persistent asthma?\nContext: {'contexts': ['Exacerbation-associated uncontrolled asthma represents a major public health problem. The relationship of elevated blood eosinophils to thi... |
[
{
"from": "human",
"value": "Question: Do phosphorus application and elevated CO2 enhance drought tolerance in field pea grown in a phosphorus-deficient vertisol?\nContext: {'contexts': ['Benefits to crop productivity arising from increasing CO2 fertilization may be offset by detrimental effects of global c... |
[
{
"from": "human",
"value": "Question: Do parental characteristics have a larger effect on children 's health behaviour than their body weight?\nContext: {'contexts': [\"Parents take an important role in a child's development, but there is currently limited information on parental correlates with children's... |
[
{
"from": "human",
"value": "Question: Do elevated levels of preoperative circulating CD44⁺ lymphocytes and neutrophils predict poor survival for non-small cell lung cancer patients?\nContext: {'contexts': ['Certain circulating cells have been shown to predict the clinical outcome of several cancers. The ob... |
[
{
"from": "human",
"value": "Question: Does cardiac-specific ablation of synapse-associated protein SAP97 in mice decrease potassium currents but not sodium current?\nContext: {'contexts': ['Membrane-associated guanylate kinase (MAGUK) proteins are important determinants of ion channel organization in the p... |
[
{
"from": "human",
"value": "Question: Does imaging DNA damage allow detection of preneoplasia in the BALB-neuT model of breast cancer?\nContext: {'contexts': ['A prominent feature of many human cancers is oncogene-driven activation of the DNA damage response (DDR) during early tumorigenesis. It has been sh... |
[
{
"from": "human",
"value": "Question: Does glioma-derived versican promote tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling?\nContext: {'contexts': ['Accumulation and infiltration of microglia/brain macrophages around and into glioma tissue promote tumor invasion ... |
[
{
"from": "human",
"value": "Question: Is care of patients undergoing vascular surgery at safety net public hospitals associated with higher cost but similar mortality to nonsafety net hospitals?\nContext: {'contexts': ['This study compared in-hospital mortality and resource utilization among vascular surgi... |
[
{
"from": "human",
"value": "Question: Does older age limit postbariatric surgery cognitive benefits : a preliminary investigation?\nContext: {'contexts': ['Bariatric surgery is associated with cognitive benefits, but the nature of such gains may be variable across demographically and clinically diverse per... |
[
{
"from": "human",
"value": "Question: Is self-reported sleep disturbance associated with Alzheimer 's disease risk in men?\nContext: {'contexts': ['To study the association between self-reported sleep disturbances and dementia risk.', 'Self-reported sleep disturbances and established risk factors for demen... |
[
{
"from": "human",
"value": "Question: Does a group of segmental premotor interneurons regulate the speed of axial locomotion in Drosophila larvae?\nContext: {'contexts': ['Animals control the speed of motion to meet behavioral demands. Yet, the underlying neuronal mechanisms remain poorly understood. Here ... |
[
{
"from": "human",
"value": "Question: Do plasma membrane-targeted PIN proteins drive shoot development in a moss?\nContext: {'contexts': ['Plant body plans arise by the activity of meristematic growing tips during development and radiated independently in the gametophyte (n) and sporophyte (2n) stages of t... |
[
{
"from": "human",
"value": "Question: Do axonal Charcot-Marie-Tooth disease patient-derived motor neurons demonstrate disease-specific phenotypes including abnormal electrophysiological properties?\nContext: {'contexts': ['Charcot-Marie-Tooth (CMT) disease is a group of inherited peripheral neuropathies as... |
[
{
"from": "human",
"value": "Question: Does gastroprotective effect of the iridoid fraction from Barleria prionitis leave on experimentally-induced gastric ulceration?\nContext: {'contexts': ['To study the gastroprotective effect and in vivo antioxidant potential of a standardized iridoid fraction from B. p... |
[
{
"from": "human",
"value": "Question: Does tetramethylpyrazine protect lymphocytes from radiation-induced apoptosis through nuclear factor-κB?\nContext: {'contexts': ['Radiation induces an important apoptosis response in irradiated organs. The objective of this study was to investigate the radioprotective ... |
[
{
"from": "human",
"value": "Question: Is persistent insomnia associated with mortality risk?\nContext: {'contexts': ['Insomnia has been associated with mortality risk, but whether this association is different in subjects with persistent vs intermittent insomnia is unclear. Additionally, the role of system... |
[
{
"from": "human",
"value": "Question: Does vitamin E attenuate neurotoxicity induced by deltamethrin in rats?\nContext: {'contexts': ['The safety of Deltamethrin (DM) has been raised as a point of concern. The current investigation was envisaged to explore the responsiveness of oxidative stress parameters,... |
[
{
"from": "human",
"value": "Question: Does glial cell line-derived neurotrophic factor promote β-catenin phosphorylation and nuclear translocation in glioma cells?\nContext: {'contexts': ['Glial cell line-derived neurotrophic factor (GDNF) and N-cadherin interact to transduce intracellular signals. However... |
[
{
"from": "human",
"value": "Question: Does statin treatment affect cytokine release and phagocytic activity in primary cultured microglia through two separable mechanisms?\nContext: {'contexts': ['As the primary immune cells of the central nervous system, microglia contribute to development, homeostasis, a... |
[
{
"from": "human",
"value": "Question: Are the Expression of RAC1 and Mineralocorticoid Pathway-Dependent Genes Associated With Different Responses to Salt Intake?\nContext: {'contexts': ['Rac1 upregulation has been implicated in salt-sensitive hypertension as a modulator of mineralocorticoid receptor (MR) ... |
[
{
"from": "human",
"value": "Question: Are statin medications associated with a lower probability of having an abnormal screening prostate-specific antigen result?\nContext: {'contexts': ['To investigate how statin use is associated with the probability of having an abnormal screening prostate-specific anti... |
[
{
"from": "human",
"value": "Question: Does systemic delivery of human bone marrow embryonic-like stem cells improve motor function of severely affected dystrophin/utrophin-deficient mice?\nContext: {'contexts': ['Embryonic-like stem cells (ELSCs) express embryonic stem cell-specific marker genes, such as S... |
[
{
"from": "human",
"value": "Question: Is uRG4 overexpression correlated with cervical cancer progression and poor prognosis in patients with early-stage cervical cancer?\nContext: {'contexts': ['Upregulator of cell proliferation 4 (URG4) has been implicated in the oncogenesis of certain cancers. However, t... |
[
{
"from": "human",
"value": "Question: Is fragmented QRS associated with frequency of premature ventricular contractions in patients without overt cardiac disease?\nContext: {'contexts': ['In this study, we aimed to demonstrate whether the presence of fragmented QRS (fQRS) is associated with the frequency o... |
[
{
"from": "human",
"value": "Question: Does adjustment of sensitisation and challenge protocols restore functional and inflammatory responses to ovalbumin in guinea-pigs?\nContext: {'contexts': ['Inhalation of antigen in atopic asthma induces early (EAR) and late asthmatic responses (LARs), inflammatory cel... |
[
{
"from": "human",
"value": "Question: Is expression of growth arrest and DNA damage inducible 45a in human oral squamous cell carcinoma associated with tumor progression and clinical outcome?\nContext: {'contexts': ['The aim of this study was to examine the growth arrest and DNA damage-inducible (Gadd45a) ... |
[
{
"from": "human",
"value": "Question: Does alteration of inflammatory response by shock wave therapy lead to reduced calcification of decellularized aortic xenografts in mice†?\nContext: {'contexts': ['Tissue-engineered xenografts represent a promising treatment option in heart valve disease. However, infl... |
[
{
"from": "human",
"value": "Question: Does multicenter immunohistochemical ALK-testing of non-small-cell lung cancer show high concordance after harmonization of techniques and interpretation criteria?\nContext: {'contexts': ['Detection of anaplastic lymphoma kinase (ALK)-gene rearrangements in non-small-c... |
[
{
"from": "human",
"value": "Question: Does the novel surfactant protein SP-H enhance the phagocytosis efficiency of macrophage-like cell lines U937 and MH-S?\nContext: {'contexts': ['Surfactant proteins (SP) secreted by alveolar type 2 cells, play an essential role in maintaining the air-liquid barrier of ... |
[
{
"from": "human",
"value": "Question: Does the rtPA increase MMP-9 activity in serum during ischaemic stroke?\nContext: {'contexts': [\"To find the relationship between rtPA treatment vs. MMP-9 activity, MMP-3, and TIMP-1 serum levels related to patients' neurological status during acute ischaemic stroke (... |
[
{
"from": "human",
"value": "Question: Does tRAIL receptor deletion in mice suppress the inflammation of nutrient excess?\nContext: {'contexts': ['Low-grade chronic inflammation is a cardinal feature of the metabolic syndrome, yet its pathogenesis is not well defined. The purpose of this study was to examin... |
[
{
"from": "human",
"value": "Question: Are hospitalisation costs for infant bronchiolitis up to 20 times higher if intensive care is needed?\nContext: {'contexts': ['Up to 3% of infants with bronchiolitis under 12 months of age are hospitalised, and up to 9% require intensive care. We evaluated the costs of... |
[
{
"from": "human",
"value": "Question: Is hospital readmission associated with poor survival after esophagectomy for esophageal cancer?\nContext: {'contexts': ['Hospital readmissions are costly and associated with inferior patient outcomes. There is limited knowledge related to readmissions after esophagect... |
[
{
"from": "human",
"value": "Question: Does polyphenol-enriched diet prevent coronary endothelial dysfunction by activating the Akt/eNOS pathway?\nContext: {'contexts': ['The Mediterranean diet, rich in polyphenols, has shown to be cardioprotective. However the mechanisms involved remain unknown. We investi... |
[
{
"from": "human",
"value": "Question: Is malnutrition a prognostic factor in patients with hepatocellular carcinoma ( HCC )?\nContext: {'contexts': ['Malnutrition is a common, hence frequently underdiagnosed condition in patients with liver cirrhosis as well as in patients with cancer and has been shown to... |
[
{
"from": "human",
"value": "Question: Is histiocytoid Sweet syndrome infiltrated predominantly by M2-like macrophages?\nContext: {'contexts': ['Histiocytoid Sweet syndrome (HSS) is a rare variant of Sweet syndrome (SS). The nature of histiocytoid cells is still uncertain.', 'We sought to offer a comprehens... |
[
{
"from": "human",
"value": "Question: Is sinR a mutational target for fine-tuning biofilm formation in laboratory-evolved strains of Bacillus subtilis?\nContext: {'contexts': ['Bacteria often form multicellular, organized communities known as biofilms, which protect cells from a variety of environmental st... |
[
{
"from": "human",
"value": "Question: Does ancient DNA provide new insight into the maternal lineages and domestication of Chinese donkeys?\nContext: {'contexts': ['The donkey (Equus asinus) is an important domestic animal that provides a reliable source of protein and method of transportation for many hum... |
[
{
"from": "human",
"value": "Question: Do a critical analysis of secondary overtriage to a Level I trauma center?\nContext: {'contexts': ['Trauma centers often receive transfers from lower-level trauma centers or nontrauma hospitals. The aim of this study was to analyze the incidence and pattern of secondar... |
[
{
"from": "human",
"value": "Question: Is fibromyalgia associated with coronary heart disease : a population-based cohort study?\nContext: {'contexts': ['We examined whether patients with a diagnosis of fibromyalgia have an increased risk of coronary heart disease (CHD), compared with age- and sex-matched c... |
[
{
"from": "human",
"value": "Question: Do serum miRNA biomarkers serve as a fingerprint for proliferative diabetic retinopathy?\nContext: {'contexts': ['Diabetic retinopathy (DR) is a retinopathy resulting from diabetes mellitus (DM) which was classified into non-proliferative DR (NPDR) and proliferative DR... |
[
{
"from": "human",
"value": "Question: Does the usage of overtube have a favorable effect on endoscopic submucosal dissection?\nContext: {'contexts': ['Endoscopic submucosal dissection (ESD) may be very time consuming, and depending on the anesthesia, the contents of the stomach may reflux to the esophagus ... |
[
{
"from": "human",
"value": "Question: Do dehydroepiandrosterone and its sulfate predict the 5-year risk of coronary heart disease events in elderly men?\nContext: {'contexts': ['The adrenal sex hormone dehydroepiandrosterone (DHEA), which is present in serum mainly as the sulfate DHEA-S, is the most abunda... |
[
{
"from": "human",
"value": "Question: Does aeromonas piscicola AH-3 express an extracellular collagenase with cytotoxic properties?\nContext: {'contexts': ['The aim of this study was to investigate the presence and the phenotypic expression of a gene coding for a putative collagenase. This gene (AHA_0517) ... |
[
{
"from": "human",
"value": "Question: Does preoperative anemia increase postoperative morbidity in elective cranial neurosurgery?\nContext: {'contexts': ['Preoperative anemia may affect postoperative mortality and morbidity following elective cranial operations.', 'The American College of Surgeons National... |
[
{
"from": "human",
"value": "Question: Does endothelin-Bone morphogenetic protein type 2 receptor interaction induce pulmonary artery smooth muscle cell hyperplasia in pulmonary arterial hypertension?\nContext: {'contexts': ['Endothelin receptor antagonists improve pulmonary arterial hypertension (PAH). Mut... |
[
{
"from": "human",
"value": "Question: Do long-term results from the Contura multilumen balloon breast brachytherapy catheter phase 4 registry trial?\nContext: {'contexts': ['To describe the long-term outcomes from a completed, multi-institutional phase 4 registry trial using the Contura multilumen balloon ... |
[
{
"from": "human",
"value": "Question: Does selenium status in pregnancy influence children 's cognitive function at 1.5 years of age?\nContext: {'contexts': ['Selenium deficiency has been shown to affect the neurological development in animals, but human research in this area is scarce. We aimed to assess ... |
[
{
"from": "human",
"value": "Question: Does dexmedetomidine reduce atrial fibrillation after lung cancer surgery?\nContext: {'contexts': ['To evaluate whether the use of intraoperative dexmedetomidine (DEX) during lung cancer surgery may reduce the incidence of postoperative atrial fibrillation (POAF).', 'A... |
[
{
"from": "human",
"value": "Question: Does extracorporeal shockwave therapy improve short-term functional outcomes of shoulder adhesive capsulitis?\nContext: {'contexts': ['The treatment of adhesive capsulitis is a dilemma for orthopaedic rehabilitation specialists. In this study, we assessed whether extra... |
[
{
"from": "human",
"value": "Question: Do collateral flow and brain changes on computed tomography angiography predict infarct volume on early diffusion-weighted imaging?\nContext: {'contexts': ['We investigated whether a computed tomography (CT)-based score could predict a large infarct (≥ 80 mL) on early ... |
[
{
"from": "human",
"value": "Question: Do angiogenic microvascular endothelial cells release microparticles rich in tissue factor that promotes postischemic collateral vessel formation?\nContext: {'contexts': ['Therapeutic angiogenesis is a promising strategy for treating ischemia. Our previous work showed ... |
[
{
"from": "human",
"value": "Question: Does adenovirus-mediated NDRG2 inhibit the proliferation of human renal cell carcinoma cell line OS-RC-2 in vitro?\nContext: {'contexts': ['To investigate the inhibitory effects of adenovirus-mediated NDRG2 on the proliferation of human renal cell carcinoma cell line O... |
[
{
"from": "human",
"value": "Question: Does introduction of an 8-aminooctanoic acid linker enhance uptake of 99mTc-labeled lactam bridge-cyclized α-MSH peptide in melanoma?\nContext: {'contexts': ['The purpose of this study was to examine the effects of amino acid, hydrocarbon, and polyethylene glycol (PEG)... |
[
{
"from": "human",
"value": "Question: Does bRCAness predict resistance to taxane-containing regimens in triple negative breast cancer during neoadjuvant chemotherapy?\nContext: {'contexts': ['To provide optimal treatment of heterogeneous triple negative breast cancer (TNBC), we need biomarkers that can pre... |
[
{
"from": "human",
"value": "Question: Does classical swine fever virus induce oxidative stress in swine umbilical vein endothelial cells?\nContext: {'contexts': ['Classical swine fever virus (CSFV) infection causes significant losses of pigs, which is characterized by hemorrhage, disseminated intravascular... |
[
{
"from": "human",
"value": "Question: Does e2F4 regulatory program predict patient survival prognosis in breast cancer?\nContext: {'contexts': ['Genetic and molecular signatures have been incorporated into cancer prognosis prediction and treatment decisions with good success over the past decade. Clinicall... |
[
{
"from": "human",
"value": "Question: Do long-term efficacy of the Baerveldt 250 mm2 compared with the Baerveldt 350 mm2 implant?\nContext: {'contexts': ['To investigate the long-term surgical outcomes of the Baerveldt 250 mm2 versus Baerveldt 350 mm2 glaucoma drainage implants (GDIs) (Abbott Laboratories ... |
[
{
"from": "human",
"value": "Question: Is self-reported body fat change in HIV-infected men a marker of decline in physical health-related quality of life with aging , independent of co-morbidity?\nContext: {'contexts': ['Self-perception of changes in body fat among HIV+ persons is associated with decreased... |
[
{
"from": "human",
"value": "Question: Does transcranial magnetic stimulation reveal cortical hyperexcitability in episodic cluster headache?\nContext: {'contexts': ['Evidence shows involvement of the cerebral cortex in the pathophysiology of cluster headache (CH). Here we investigated cortical excitability... |
[
{
"from": "human",
"value": "Question: Is motor cortical activity during motor tasks normal in patients with complex regional pain syndrome?\nContext: {'contexts': ['Motor dysfunction in complex regional pain syndrome (CRPS) is often considered a functional movement disorder. Earlier studies in patients wit... |
[
{
"from": "human",
"value": "Question: Does peripheral group I metabotropic glutamate receptor activation lead to muscle mechanical hyperalgesia through TRPV1 phosphorylation in the rat?\nContext: {'contexts': ['Elevated glutamate levels within injured muscle play important roles in muscle pain and hyperalg... |
[
{
"from": "human",
"value": "Question: Does lipopolysaccharide preconditioning induce neuroprotection against early brain injury after experimental subarachnoid hemorrhage?\nContext: {'contexts': ['Subarachnoid hemorrhage (SAH) is a devastating neurological injury associated with significant morbidity and m... |
[
{
"from": "human",
"value": "Question: Is loss of N-cadherin associated with loss of E-cadherin expression and poor outcomes of liver resection in hepatocellular carcinoma?\nContext: {'contexts': ['Our previous study suggested that N-cadherin was downregulated in hepatocellular carcinoma (HCC). Our aim in t... |
[
{
"from": "human",
"value": "Question: Does the dual mTORC1 and mTORC2 inhibitor PP242 show strong antitumor activity in a pheochromocytoma PC12 cell tumor model?\nContext: {'contexts': ['To assess the activity of mTOR and downstream effector proteins in the mTOR pathway after treatment with a dual mTOR com... |
[
{
"from": "human",
"value": "Question: Does s100A3 suppression inhibit in vitro and in vivo tumor growth and invasion of human castration-resistant prostate cancer cells?\nContext: {'contexts': ['To investigate the role of S100A3 and the effect of S100A3 inhibition on human castration-resistant prostate can... |
[
{
"from": "human",
"value": "Question: Does a common polymorphism within MSLN affect miR-611 binding site and soluble mesothelin levels in healthy people?\nContext: {'contexts': [\"Soluble mesothelin related peptide (SMRP) was proposed as a promising diagnostic marker for malignant pleural mesothelioma (MPM... |
[
{
"from": "human",
"value": "Question: Is [ Ischemia an independent predictive factor of chronic renal failure after partial nephrectomy in a solitary kidney in patients without pre-operative renal insufficiency ]?\nContext: {'contexts': ['To assess the influence of vascular clamping and ischemia time on lo... |
[
{
"from": "human",
"value": "Question: Does regional anesthesia improve outcome in patients undergoing proximal humerus fracture repair?\nContext: {'contexts': ['The purpose of this study was to examine functional outcomes following ORIF of displaced proximal humerus fractures in patients who received brach... |
[
{
"from": "human",
"value": "Question: Are in patients with rheumatoid arthritis , Dickkopf-1 serum levels correlated with parathyroid hormone , bone erosions and bone mineral density?\nContext: {'contexts': ['The objective of this study is to compare the serum levels of Dickkopf-1 (DKK1), a natural inhibit... |
[
{
"from": "human",
"value": "Question: Does multimodal protocol reduce postoperative nausea and vomiting in patients undergoing Le Fort I osteotomy?\nContext: {'contexts': ['To assess the impact of a multimodal antiemetic protocol on postoperative nausea and vomiting (PONV) after Le Fort I osteotomy.', 'Con... |
[
{
"from": "human",
"value": "Question: Is a high body mass index in esophageal cancer patients associated with adverse outcomes following esophagectomy?\nContext: {'contexts': ['There is no consensus about the impact of a high BMI on postoperative morbidity and survival after esophagectomy. The aim of this ... |
[
{
"from": "human",
"value": "Question: Are fascial closure after open abdomen : initial indication and early revisions decisive factors -- a retrospective cohort study?\nContext: {'contexts': ['The surgical treatment method in which the peritoneal cavity is opened anteriorly and deliberately left open, henc... |
[
{
"from": "human",
"value": "Question: Does mR imaging relaxometry allow noninvasive characterization of in vivo differentiation of muscle precursor cells?\nContext: {'contexts': ['To demonstrate the feasibility of in vivo monitoring of the myogenic differentiation process from human muscle precursor cells ... |
[
{
"from": "human",
"value": "Question: Is higher fasting glucose next day after intravenous thrombolysis independently associated with poor outcome in acute ischemic stroke?\nContext: {'contexts': ['We aimed to test the outcome-predictive power of routine fasting glucose (FG) obtained at second day after on... |
[
{
"from": "human",
"value": "Question: Is a newly developed mouse monoclonal SOX10 antibody a highly sensitive and specific marker for malignant melanoma , including spindle cell and desmoplastic melanomas?\nContext: {'contexts': ['Recent immunohistochemical studies have demonstrated Sry-related HMG-Box gen... |
[
{
"from": "human",
"value": "Question: Is abdominal aortic diameter increased in males with a family history of abdominal aortic aneurysms : results from the Danish VIVA-trial?\nContext: {'contexts': ['To investigate, at a population level, whether a family history of abdominal aortic aneurysm (AAA) is inde... |
[
{
"from": "human",
"value": "Question: Does dual-specificity phosphatase 6 predict the sensitivity of progestin therapy for atypical endometrial hyperplasia?\nContext: {'contexts': ['We previously found that Dual-specificity phosphatase 6 (Dusp6) over-expression enhanced the growth-promoting effect of estro... |
[
{
"from": "human",
"value": "Question: Does endoscopic transphenoidal surgery for acromegaly improve quality of life?\nContext: {'contexts': ['Acromegaly has important effects on quality of life (QOL). This is the first study to measure QOL in acromegalic patients after endoscopic transsphenoidal surgery (E... |
[
{
"from": "human",
"value": "Question: Is smoking history , and not depression , related to deficits in detection of happy and sad faces?\nContext: {'contexts': ['Previous research has demonstrated that chronic cigarette smoking and major depressive disorder (MDD) are each associated with cognitive decremen... |
[
{
"from": "human",
"value": "Question: Are fatty acid-amino acid conjugates essential for systemic activation of salicylic acid-induced protein kinase and accumulation of jasmonic acid in Nicotiana attenuata?\nContext: {'contexts': ['Herbivory induces the activation of mitogen-activated protein kinases (MAP... |
[
{
"from": "human",
"value": "Question: Does deficiency in Nrf2 transcription factor decrease adipose tissue mass and hepatic lipid accumulation in leptin-deficient mice?\nContext: {'contexts': ['To evaluate whether Nrf2 deficiency impacts insulin resistance and lipid accumulation in liver and white adipose ... |
[
{
"from": "human",
"value": "Question: Do bone Marrow Stromal Cells Inhibit the Activation of Liver Cirrhotic Fat-Storing Cells via Adrenomedullin Secretion?\nContext: {'contexts': ['Cirrhosis, or liver fibrosis, which is mainly triggered by cirrhosis fat-storing cells (CFSCs) activation, has traditionally ... |
[
{
"from": "human",
"value": "Question: Does obesity increase risk of anticoagulation reversal failure with prothrombin complex concentrate in those with intracranial hemorrhage?\nContext: {'contexts': ['Not all patients with warfarin-related acute intracranial hemorrhage (ICH) achieve full reversal of inter... |
[
{
"from": "human",
"value": "Question: Does rNA-seq analysis of the rat placentation site reveal maternal obesity-associated changes in placental and offspring thyroid hormone signaling?\nContext: {'contexts': ['In animal models, maternal obesity (OB) leads to augmented risk of offspring OB. While placental... |
[
{
"from": "human",
"value": "Question: Is serum free 1,25-dihydroxy-vitamin D more closely associated with fibroblast growth factor 23 than other vitamin D forms in chronic dialysis patients?\nContext: {'contexts': ['Mineral bone disorder (MBD) is prevalent among chronic dialysis patients. However, relation... |
[
{
"from": "human",
"value": "Question: Is synovial T cell hyporesponsiveness to myeloid dendritic cells reversed by preventing PD-1/PD-L1 interactions?\nContext: {'contexts': ['The aim of this study was to investigate PD-1/PD-L1 involvement in the hyporesponsiveness of rheumatoid arthritis (RA) synovial flu... |
[
{
"from": "human",
"value": "Question: Does microRNA-29b regulate migration in oral squamous cell carcinoma and its clinical significance?\nContext: {'contexts': [\"MicroRNA (miRNA) machinery regulates cancer cell behavior, and has been implicated in patients' clinical status and prognosis. We found that mi... |
[
{
"from": "human",
"value": "Question: Are pre-transplant impedance measures of reflux associated with early allograft injury after lung transplantation?\nContext: {'contexts': ['Acid reflux has been associated with poorer outcomes after lung transplantation. Standard pre-transplant reflux assessment has no... |
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