Datasets:
PranavHarshan
/
sharegpt_formatted_pubmed_rct_convo

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[ { "from": "human", "value": "Text: ['information regarding prognostic factors and survival in elderly women with metastatic breast cancer treated with tamoxifen is limited .', 'the data from @ prospective clinical trials were analyzed , including information on @ postmenopausal women with advanced breast ca...
[ { "from": "human", "value": "Text: ['to evaluate unattended full polysomnography ( psg ) recorded in the home by the digitrace home sleep system ( dhss ) and to assess the ability to acquire , store and analyze polysomnographic data using the dhss compared to standard paper psg .', 'part @ used a prospectiv...
[ { "from": "human", "value": "Text: ['ppis are widely used in peptic diseases , and this paper is to investigate the kinetic characteristics of a new ppi ilaprazole in chinese healthy subjects and the association with cyp@a@ and cyp@c@ polymorphisms .', '@ subjects were selected and treated with @mg ilaprazo...
[ { "from": "human", "value": "Text: ['gd-dtpa is a well-characterized , safe contrast agent frequently used in magnetic resonance imaging ( mri ) of the central nervous system .', 'the purpose of this double-blind , comparative mri study of brain , spine , trunk , and limbs was to evaluate the safety and eff...
[ { "from": "human", "value": "Text: ['this study included @-month-old children with a history of institutional care .', 'our goal was to : ( @ ) examine differences in indiscriminate social behaviors in children with a history of institutional care compared with home-reared children ; ( @ ) test whether fost...
[ { "from": "human", "value": "Text: ['to compare the effect of delapril/manidipine vs olmesartan/hydrochlorothiazide ( hctz ) combination on insulin sensitivity and plasma fibrinogen in obese hypertensive patients .', 'after a @-week placebo period , @ obese , hypertensive ( dbp > @ and < @ mmhg ) outpatient...
[ { "from": "human", "value": "Text: ['to test whether consumption of a beverage containing active ingredients will increase @-hour energy metabolism in healthy , young , lean individuals .', 'thirty-one male and female subjects consumed @ x @-ml servings of a beverage containing green tea catechins , caffein...
[ { "from": "human", "value": "Text: ['dexlansoprazole mr , a modified-release formulation of dexlansoprazole , an enantiomer of lansoprazole , effectively heals erosive oesophagitis .', 'to assess dexlansoprazole mr in maintaining healed erosive oesophagitis .', 'patients ( n = @ ) with erosive oesophagitis ...
[ { "from": "human", "value": "Text: ['the pathophysiology of anemia in coastal east africa is complex .', 'impaired erythropoietin production is one possible mechanism .', 'plasmodium falciparum malaria has been found to blunt erythropoietin production , whereas vitamin a stimulates erythropoietin production...
[ { "from": "human", "value": "Text: ['an external straightener for colonoscopy which enables proper compression of the abdomen during the entire examination has been developed .', 'beginning january @ , @ , patients undergoing outpatient colonoscopy were subjected to either manual abdominal compression or co...
[ { "from": "human", "value": "Text: ['intravenous acetaminophen injection ( paracetamol ) is marketed in europe for the management of acute pain .', 'a repeated-dose , randomized , double-blind , placebo-controlled , three-parallel group study was performed to evaluate the analgesic efficacy and safety of in...
[ { "from": "human", "value": "Text: ['to assess whether heat trapped under ophthalmic drapes is responsible for patient reports of being hot during cataract surgery using local anesthesia .', 'departments of anaesthesia and intensive care medicine and of ophthalmology and optometry , innsbruck university hos...
[ { "from": "human", "value": "Text: ['combining targeted treatments for renal cell carcinoma has been suggested as a possible method to improve treatment efficacy .', 'we aimed to assess the potential synergistic or additive effect of the combination of bevacizumab , directed against the vegf receptor , and ...
[ { "from": "human", "value": "Text: ['wound pain is a serious problem for people with chronic wounds .', 'the aim of this real-life study was to compare the effect of a foam dressing that releases ibuprofen ( biatain ibu ) with local best practice on the treatment of painful exuding wounds .', 'a total of @ ...
[ { "from": "human", "value": "Text: ['to determine if a @-month course of therapy with imreg-@ , a leukocyte-derived immunomodulator , slows disease progression in patients with aids-related complex .', 'randomized , double-blind trial .', 'five academic - and three community-based clinics .', 'immunocomprom...
[ { "from": "human", "value": "Text: ['tracheal intubation in the lateral position is difficult because the laryngeal view is compromised during direct laryngoscopy .', 'the airway scope facilitates intubation even when laryngeal views are poor with direct laryngoscopy , as they often are in the lateral posit...
[ { "from": "human", "value": "Text: ['to evaluate the effect of veno-venous continuous renal replacement therapy ( crrt ) on the plasma levels of endotoxin and cytokines in severely burned patients with sepsis .', 'twenty adult severely burned patients with sepsis were studied .', 'for the diagnosis of sepsi...
[ { "from": "human", "value": "Text: ['to study the effect of shenqi fuzheng injection ( sfi ) on cellular immune in patients with mammary cancer ( mc ) after chemotherapy .', 'one hundred and ten patients with mc were randomly assigned to two groups .', 'the @ patients in the tested group were treated with s...
[ { "from": "human", "value": "Text: ['probiotics are microbial supplements that have shown efficacy in a wide range of applications .', 'to assess the safety and effects of enteral probiotics in critically ill neonates .', 'a double-blind , randomized controlled trial was conducted in @ full-term infants wit...
[ { "from": "human", "value": "Text: ['decreases in prefrontal electroencephalogram ( eeg ) cordance that are detectable as early as @ hours after the start of medication have been related to clinical outcome in treatment trials for major depressive disorder .', 'the relationship between brain changes during ...
[ { "from": "human", "value": "Text: [\"late onset hypogonadism negatively impacts on men 's psychological well-being .\", 'this study was conducted to examine the interrelationship among symptoms of testosterone deficiency , psychological well-being , and quality of life .', \"eligible subjects were randomiz...
[ { "from": "human", "value": "Text: ['methyl aminolaevulinate-photodynamic therapy ( mal-pdt ) is an effective treatment in facial/scalp actinic keratosis ( ak ) .', 'the aims of this study were to compare efficacy , safety , cosmetic outcome and patient preference of mal-pdt vs. cryotherapy in patients with...
[ { "from": "human", "value": "Text: ['to determine whether patients with borderline semen should be treated with conventional ivf or intracytoplasmic sperm injection ( icsi ) .', 'randomized study .', 'a university medical center in the netherlands .', 'one hundred six couples with borderline semen who were ...
[ { "from": "human", "value": "Text: ['to explore the quality of data recording by practices and identify issues to be considered and addressed before such data can be used as a continuous measure of immunisation delivery .', 'one hundred and twenty-four randomly selected general practices visited to measure ...
[ { "from": "human", "value": "Text: ['the impact of preoperative gabapentin on tramadol consumption using patient-controlled analgesia ( pca ) and postoperative pain was assessed in patients undergoing radical retropubic prostatectomy ( rrp ) .', 'in this prospective , randomized trial , @ patients undergoin...
[ { "from": "human", "value": "Text: ['to evaluate and compare the safety and efficacy of cisatracurium ( @w@ ) and atracurium administered by continuous infusion to critically ill patients requiring neuromuscular blocking agents to facilitate mechanical ventilation .', 'open , randomized , multicenter study ...
[ { "from": "human", "value": "Text: ['to compare the efficacy of standard medical therapy ( st ) and noninvasive mechanical ventilation additional to standard medical therapy in hypercapnic acute respiratory failure ( harf ) .', 'single center , prospective , randomized , controlled study .', 'pulmonary medi...
[ { "from": "human", "value": "Text: [\"patients with crohn 's disease ( cd ) often require surgery over their clinical course .\", 'however , endoscopic and clinical recurrence of disease appear respectively in up to @ % and @ % of patients after one year .', 'thus , a prophylactic treatment is needed to red...
[ { "from": "human", "value": "Text: ['immediate loading of osseointegrating implants shortens the treatment time and makes it possible to give the patient an esthetic appearance during the whole treatment period .', 'a previous retrospective clinical study showed a success rate of @ % after @ year of immedia...
[ { "from": "human", "value": "Text: ['to compare intracameral levels and clinical efficacy of lidocaine @ % gel with lidocaine @ % unpreserved drops .', 'double-blind , randomized , one-surgeon , controlled trial .', 'one hundred seven consecutive cataract cases eligible for topical anesthesia .', 'patients ...
[ { "from": "human", "value": "Text: ['psychosocial stress profoundly impacts long-term cardiovascular health through adverse effects on sympathetic nervous system activity , endothelial dysfunction , and atherosclerotic development .', 'recreational music making ( rmm ) is a unique stress amelioration strate...
[ { "from": "human", "value": "Text: ['the goal of this study was to determine whether azimilide , as compared with placebo , will reduce the number of emergency department ( ed ) visits and hospitalizations caused by arrhythmias or cardiac events in patients with an implantable cardioverter-defibrillator ( i...
[ { "from": "human", "value": "Text: ['our aim was to test the hypothesis that acetylsalicylate ( aspirin ) treatment reduces the incidence or severity of pregnancy-associated hypertension .', \"patients were nulliparous , healthy , and with a singleton gestation at between @ and @ weeks ' gestation .\", 'a s...
[ { "from": "human", "value": "Text: ['to assess the efficacy and safety of interferon-alpha ( ifn-alpha ) in children with hepatitis b e antigen-positive chronic hepatitis b virus infection .', 'pubmed and chinese biomedical database were searched from the beginning of operation of the databases to april @ ,...
[ { "from": "human", "value": "Text: ['submassive pulmonary embolism ( pe ) has a low mortality rate but can degrade functional capacity .', 'the present study aims to provide rationale , methodology , and initial findings of a multicentre , randomised trial of fibrinolysis for pe that used a composite end-po...
[ { "from": "human", "value": "Text: ['to compare in vivo bitewing film quality using the holder versus the paper loop technique .', 'four bitewing films were taken from the right and left premolar and molar regions of @ dental students using both the bitewing holder and paper loop techniques .', 'a total of ...
[ { "from": "human", "value": "Text: ['to evaluate clinical efficacy and toxicity of low-dose oral natural human interferon-alpha ( nhuifn alpha ) on cd@ + lymphocyte counts and clinical symptoms in patients with hiv-@ infection .', 'double-blind , randomized , placebo-controlled trial with crossover .', 'pri...
[ { "from": "human", "value": "Text: ['blue-light light-emitting diode ( led ) therapy has become widely used for the treatment of inflammatory acne .', 'in this study we evaluated the efficacy of a home use blue-light led application in improving lesions and shortening their time to clearance .', 'this was a...
[ { "from": "human", "value": "Text: ['few treatments are available for isolated pulmonary hypertension ( pht ) , which has a high morbidity and mortality .', 'this trial was designed to assess the hemodynamic effects of bosentan , an endothelin receptor antagonist , in patients with pht , in which local over...
[ { "from": "human", "value": "Text: ['to compare the prophylactic administration of ondansetron plus droperidol , droperidol plus metoclopramide , and perphenazine to determine effects on postoperative nausea , vomiting , and sedation after laparoscopic cholecystectomy .', 'prospective , randomized , double-...
[ { "from": "human", "value": "Text: ['in prior studies , pregabalin reduced rectal or colonic pain in patients with irritable bowel syndrome and healthy adults , suggesting reduction of afferent function .', 'to assess effects of pregabalin on colonic compliance , sensory and motor functions in patients with...
[ { "from": "human", "value": "Text: ['topical corticosteroids , commonly used for psoriasis , show diminished response on continuous use .', 'we tested efficacy of topical corticosteroid and calcipotriene used on alternate weeks versus daily corticosteroid in patients with psoriasis .', 'in a randomized , ob...
[ { "from": "human", "value": "Text: ['ghrelin stimulates gh secretion and regulates energy and glucose metabolism .', 'the two circulating isoforms , acyl ( ag ) and des-acyl ( dag ) ghrelin , have distinct metabolic effects and are under active investigation for their therapeutic potentials .', 'however , t...
[ { "from": "human", "value": "Text: ['chest physiotherapy ( cpt ) is an integral part of the treatment of patients with cystic fibrosis ( cf ) .', 'cpt imposes additional respiratory work that may carry a risk of respiratory muscle fatigue .', \"inspiratory pressure support ventilation ( psv ) is a new mode ...
[ { "from": "human", "value": "Text: ['comparing efficacy and safety of ibutilide vs. transoesophageal atrial pacing ( atp ) for the termination of type i atrial flutter ( afl ) .', \"eighty-seven patients affected by afl lasting between @ h and @ days were randomized in two groups : group @-i.v. ibutilide tr...
[ { "from": "human", "value": "Text: ['this study aimed to describe the short-term effects of low-intensity laser treatment in eyes with drusen at risk of having choroidal neovascularization ( cnv ) develop secondary to age-related macular degeneration .', 'the study design was a multicentered , randomized cl...
[ { "from": "human", "value": "Text: ['the objective of this trial was to compare the effectiveness of intraarticular injection of highly cross-linked hyaluronic acid ( ha ) with intraarticular injection of gaseous oxygen ( o @ ) in patients with clinical symptoms of cartilage damage in the knee .', 'based on...
[ { "from": "human", "value": "Text: ['to evaluate the safety and tolerability of adjunctive brivaracetam ( brv ) , a high-affinity synaptic vesicle protein @a ( sv@a ) ligand , in adults with uncontrolled epilepsy .', 'efficacy was also assessed in patients with focal seizures as a secondary objective , and ...
[ { "from": "human", "value": "Text: ['whether continuous renal replacement therapy is better than intermittent haemodialysis for the treatment of acute renal failure in critically ill patients is controversial .', 'in this study , we compare the effect of intermittent haemodialysis and continuous venovenous ...
[ { "from": "human", "value": "Text: ['this study clinically evaluates the @-year results of connective tissue graft ( ctg ) and guided tissue regeneration ( gtr ) therapies using bioabsorbable barriers for root coverage ( i.e. , the reduction of recession depth ) .', 'in @ patients , @ miller class i and ii ...
[ { "from": "human", "value": "Text: ['to compare the quality of real-time sonographic images obtained from the examinations using two different sound media , ultrasound gel and olive oil .', 'a randomized controlled trial was conducted on the study population recruited from the routine ultrasound service wit...
[ { "from": "human", "value": "Text: ['because the source of protein may play a role in its satiating effect , we investigated the effect of different proteins on satiation and short-term satiety .', 'two randomized single-blind cross-over studies were completed .', 'in the first study , we investigated the e...
[ { "from": "human", "value": "Text: ['irregularity measures have been suggested as risk indicators in patients with atrial fibrillation ( af ) ; however , it is not known to what extent they are affected by commonly used rate-control drugs .', 'we aimed at evaluating the effect of metoprolol , carvedilol , d...
[ { "from": "human", "value": "Text: ['internal medicine residents must be competent in advanced cardiac life support ( acls ) for board certification .', 'the purpose was to use a medical simulator to assess baseline proficiency in acls and determine the impact of an intervention on skill development .', 'th...