row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:5465145 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,145 | train | mutant | 5,058,548 | 5,064,797 | 5,065,216 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G277E | G277E | 1 | 1 | 0 | 0 | 277 | G | E | 8 | CONSERVATION | null | false | false | null | null | 5,457,027 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.087287 | 0.065211 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906736,"numValue":0.0872868997100796,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906737,"numValue":0.06521059856168,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463213,"numValue":8.0,"position":277,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465146 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,146 | train | mutant | 5,058,549 | 5,064,797 | 5,065,217 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G277F | G277F | 1 | 1 | 0 | 0 | 277 | G | F | 8 | CONSERVATION | null | false | false | null | null | 5,457,028 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.541972 | 0.121108 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906738,"numValue":-0.541971621361651,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906739,"numValue":0.121108304875738,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463213,"numValue":8.0,"position":277,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465147 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,147 | train | mutant | 5,058,889 | 5,064,797 | 5,065,557 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G277H | G277H | 1 | 1 | 0 | 0 | 277 | G | H | 8 | CONSERVATION | null | false | false | null | null | 5,457,369 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.090423 | 0.146986 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907420,"numValue":-0.0904227573442507,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907421,"numValue":0.146986350440564,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463213,"numValue":8.0,"position":277,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465148 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,148 | train | mutant | 5,058,890 | 5,064,797 | 5,065,558 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G277I | G277I | 1 | 1 | 0 | 0 | 277 | G | I | 8 | CONSERVATION | null | false | false | null | null | 5,457,370 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.684607 | 0.188411 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907422,"numValue":-0.684607384001727,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907423,"numValue":0.188411088329175,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463213,"numValue":8.0,"position":277,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465150 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,150 | train | mutant | 5,058,892 | 5,064,797 | 5,065,560 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G277L | G277L | 1 | 1 | 0 | 0 | 277 | G | L | 8 | CONSERVATION | null | false | false | null | null | 5,457,372 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.22063 | 0.06431 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907426,"numValue":-0.220630122930864,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907427,"numValue":0.0643099517590892,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463213,"numValue":8.0,"position":277,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465151 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,151 | train | mutant | 5,058,893 | 5,064,797 | 5,065,561 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G277M | G277M | 1 | 1 | 0 | 0 | 277 | G | M | 8 | CONSERVATION | null | false | false | null | null | 5,457,373 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.068299 | 0.14667 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907428,"numValue":-0.0682990573271924,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907429,"numValue":0.146669740047818,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463213,"numValue":8.0,"position":277,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465152 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,152 | train | mutant | 5,058,894 | 5,064,797 | 5,065,562 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G277N | G277N | 1 | 1 | 0 | 0 | 277 | G | N | 8 | CONSERVATION | null | false | false | null | null | 5,457,374 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.121324 | 0.126333 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907430,"numValue":0.121323736538969,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907431,"numValue":0.12633271784647,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463213,"numValue":8.0,"position":277,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465153 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,153 | train | mutant | 5,058,895 | 5,064,797 | 5,065,563 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G277P | G277P | 1 | 1 | 0 | 0 | 277 | G | P | 8 | CONSERVATION | null | false | false | null | null | 5,457,375 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.764589 | 0.150876 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907432,"numValue":-0.764588730624807,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907433,"numValue":0.150875535915228,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463213,"numValue":8.0,"position":277,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465156 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,156 | train | mutant | 5,058,898 | 5,064,797 | 5,065,566 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G277S | G277S | 1 | 1 | 0 | 0 | 277 | G | S | 8 | CONSERVATION | null | false | false | null | null | 5,457,378 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.090137 | 0.063385 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907438,"numValue":0.090136881088242,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907439,"numValue":0.0633847469177143,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463213,"numValue":8.0,"position":277,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465157 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,157 | train | mutant | 5,058,899 | 5,064,797 | 5,065,567 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G277T | G277T | 1 | 1 | 0 | 0 | 277 | G | T | 8 | CONSERVATION | null | false | false | null | null | 5,457,379 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.138633 | 0.085585 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907440,"numValue":-0.138633397487266,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907441,"numValue":0.0855854188727811,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463213,"numValue":8.0,"position":277,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465158 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,158 | train | mutant | 5,058,900 | 5,064,797 | 5,065,568 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G277V | G277V | 1 | 1 | 0 | 0 | 277 | G | V | 8 | CONSERVATION | null | false | false | null | null | 5,457,380 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.352124 | 0.073096 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907442,"numValue":-0.352124419512956,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907443,"numValue":0.0730962462835263,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463213,"numValue":8.0,"position":277,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465159 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,159 | train | mutant | 5,058,901 | 5,064,797 | 5,065,569 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G277W | G277W | 1 | 1 | 0 | 0 | 277 | G | W | 8 | CONSERVATION | null | false | false | null | null | 5,457,381 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.20848 | 0.132182 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907444,"numValue":-0.208479894207052,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907445,"numValue":0.132182155832898,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463213,"numValue":8.0,"position":277,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465162 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,162 | train | mutant | 5,058,551 | 5,064,797 | 5,065,219 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G278C | G278C | 1 | 1 | 0 | 0 | 278 | G | C | 5 | CONSERVATION | null | false | false | null | null | 5,457,031 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.362363 | 0.108565 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906744,"numValue":-0.362363375206407,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906745,"numValue":0.108565069476431,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463214,"numValue":5.0,"position":278,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465163 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,163 | train | mutant | 5,058,552 | 5,064,797 | 5,065,220 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G278D | G278D | 1 | 1 | 0 | 0 | 278 | G | D | 5 | CONSERVATION | null | false | false | null | null | 5,457,032 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.077291 | 0.147823 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906746,"numValue":0.0772909876185799,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906747,"numValue":0.147823294646722,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463214,"numValue":5.0,"position":278,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465164 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,164 | train | mutant | 5,058,553 | 5,064,797 | 5,065,221 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G278E | G278E | 1 | 1 | 0 | 0 | 278 | G | E | 5 | CONSERVATION | null | false | false | null | null | 5,457,033 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.303262 | 0.147287 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906748,"numValue":-0.30326231323978,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906749,"numValue":0.14728695956847,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463214,"numValue":5.0,"position":278,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465165 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,165 | train | mutant | 5,058,554 | 5,064,797 | 5,065,222 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G278F | G278F | 1 | 1 | 0 | 0 | 278 | G | F | 5 | CONSERVATION | null | false | false | null | null | 5,457,034 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.153553 | 0.213067 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906750,"numValue":-1.15355295975091,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906751,"numValue":0.213066793370015,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463214,"numValue":5.0,"position":278,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465166 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,166 | train | mutant | 5,058,875 | 5,064,797 | 5,065,543 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G278H | G278H | 1 | 1 | 0 | 0 | 278 | G | H | 5 | CONSERVATION | null | false | false | null | null | 5,457,355 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.817623 | 0.257859 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907392,"numValue":-0.817622776430637,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907393,"numValue":0.257859016958245,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463214,"numValue":5.0,"position":278,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465167 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,167 | train | mutant | 5,058,876 | 5,064,797 | 5,065,544 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G278I | G278I | 1 | 1 | 0 | 0 | 278 | G | I | 5 | CONSERVATION | null | false | false | null | null | 5,457,356 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.718726 | 0.248632 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907394,"numValue":-0.718726373665961,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907395,"numValue":0.248631653422575,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463214,"numValue":5.0,"position":278,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465168 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,168 | train | mutant | 5,058,877 | 5,064,797 | 5,065,545 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G278K | G278K | 1 | 1 | 0 | 0 | 278 | G | K | 5 | CONSERVATION | null | false | false | null | null | 5,457,357 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.177227 | 0.098532 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907396,"numValue":-0.177226692048445,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907397,"numValue":0.0985320812834691,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463214,"numValue":5.0,"position":278,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465169 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,169 | train | mutant | 5,058,878 | 5,064,797 | 5,065,546 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G278L | G278L | 1 | 1 | 0 | 0 | 278 | G | L | 5 | CONSERVATION | null | false | false | null | null | 5,457,358 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.621292 | 0.094184 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907398,"numValue":-0.621292330397892,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907399,"numValue":0.0941836692647249,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463214,"numValue":5.0,"position":278,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465170 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,170 | train | mutant | 5,058,879 | 5,064,797 | 5,065,547 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G278M | G278M | 1 | 1 | 0 | 0 | 278 | G | M | 5 | CONSERVATION | null | false | false | null | null | 5,457,359 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.384443 | 0.144339 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907400,"numValue":-0.38444316931384,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907401,"numValue":0.14433940950225,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463214,"numValue":5.0,"position":278,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465171 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,171 | train | mutant | 5,058,880 | 5,064,797 | 5,065,548 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G278N | G278N | 1 | 1 | 0 | 0 | 278 | G | N | 5 | CONSERVATION | null | false | false | null | null | 5,457,360 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.284759 | 0.135954 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907402,"numValue":-0.284759192099163,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907403,"numValue":0.135953673469765,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463214,"numValue":5.0,"position":278,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465172 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,172 | train | mutant | 5,058,881 | 5,064,797 | 5,065,549 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G278P | G278P | 1 | 1 | 0 | 0 | 278 | G | P | 5 | CONSERVATION | null | false | false | null | null | 5,457,361 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.523202 | 0.15994 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907404,"numValue":-0.523201552290508,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907405,"numValue":0.15994005731053,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463214,"numValue":5.0,"position":278,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465173 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,173 | train | mutant | 5,058,882 | 5,064,797 | 5,065,550 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G278Q | G278Q | 1 | 1 | 0 | 0 | 278 | G | Q | 5 | CONSERVATION | null | false | false | null | null | 5,457,362 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.841465 | 0.259552 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907406,"numValue":-0.841465051319142,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907407,"numValue":0.259552419108173,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463214,"numValue":5.0,"position":278,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465175 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,175 | train | mutant | 5,058,884 | 5,064,797 | 5,065,552 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G278S | G278S | 1 | 1 | 0 | 0 | 278 | G | S | 5 | CONSERVATION | null | false | false | null | null | 5,457,364 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.209031 | 0.096075 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907410,"numValue":-0.209031157294577,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907411,"numValue":0.0960751358514093,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463214,"numValue":5.0,"position":278,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465176 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,176 | train | mutant | 5,058,885 | 5,064,797 | 5,065,553 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G278T | G278T | 1 | 1 | 0 | 0 | 278 | G | T | 5 | CONSERVATION | null | false | false | null | null | 5,457,365 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.25969 | 0.09876 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907412,"numValue":-0.25968969825227,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907413,"numValue":0.0987599041700835,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463214,"numValue":5.0,"position":278,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465177 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,177 | train | mutant | 5,058,886 | 5,064,797 | 5,065,554 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G278V | G278V | 1 | 1 | 0 | 0 | 278 | G | V | 5 | CONSERVATION | null | false | false | null | null | 5,457,366 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.234493 | 0.096617 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907414,"numValue":-0.234492682130086,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907415,"numValue":0.0966167786662922,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463214,"numValue":5.0,"position":278,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465178 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,178 | train | mutant | 5,058,887 | 5,064,797 | 5,065,555 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G278W | G278W | 1 | 1 | 0 | 0 | 278 | G | W | 5 | CONSERVATION | null | false | false | null | null | 5,457,367 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.616166 | 0.185947 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907416,"numValue":-0.616165778821282,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907417,"numValue":0.18594650326884,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463214,"numValue":5.0,"position":278,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465179 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,179 | train | mutant | 5,058,888 | 5,064,797 | 5,065,556 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | G278Y | G278Y | 1 | 1 | 0 | 0 | 278 | G | Y | 5 | CONSERVATION | null | false | false | null | null | 5,457,368 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.410547 | 0.186697 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907418,"numValue":-0.410547183960207,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907419,"numValue":0.186696708911315,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463214,"numValue":5.0,"position":278,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465180 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,180 | train | mutant | 5,058,555 | 5,064,797 | 5,065,223 | 743 | 742 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | delS279 | delS279 | 1 | 0 | 1 | 0 | 279 | S | - | 5 | CONSERVATION | null | false | false | null | null | 5,457,035 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.146234 | 0.19214 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906752,"numValue":-1.14623365923576,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906753,"numValue":0.192139675743296,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463215,"numValue":5.0,"position":279,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465182 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,182 | train | mutant | 5,058,557 | 5,064,797 | 5,065,225 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S279C | S279C | 1 | 1 | 0 | 0 | 279 | S | C | 5 | CONSERVATION | null | false | false | null | null | 5,457,037 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.059746 | 0.068246 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906756,"numValue":0.0597461861320643,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906757,"numValue":0.0682456189567433,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463215,"numValue":5.0,"position":279,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465183 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,183 | train | mutant | 5,058,558 | 5,064,797 | 5,065,226 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S279D | S279D | 1 | 1 | 0 | 0 | 279 | S | D | 5 | CONSERVATION | null | false | false | null | null | 5,457,038 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.16289 | 0.070041 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906758,"numValue":0.162889949025263,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906759,"numValue":0.070041029170035,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463215,"numValue":5.0,"position":279,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465184 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,184 | train | mutant | 5,058,559 | 5,064,797 | 5,065,227 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S279E | S279E | 1 | 1 | 0 | 0 | 279 | S | E | 5 | CONSERVATION | null | false | false | null | null | 5,457,039 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.064806 | 0.066685 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906760,"numValue":0.0648060982947309,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906761,"numValue":0.066685066332475,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463215,"numValue":5.0,"position":279,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465186 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,186 | train | mutant | 5,058,561 | 5,064,797 | 5,065,229 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S279G | S279G | 1 | 1 | 0 | 0 | 279 | S | G | 5 | CONSERVATION | null | false | false | null | null | 5,457,041 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.099383 | 0.045361 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906764,"numValue":0.0993834656554596,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906765,"numValue":0.04536093195718,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463215,"numValue":5.0,"position":279,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465187 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,187 | train | mutant | 5,058,562 | 5,064,797 | 5,065,230 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S279H | S279H | 1 | 1 | 0 | 0 | 279 | S | H | 5 | CONSERVATION | null | false | false | null | null | 5,457,042 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.290594 | 0.143548 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906766,"numValue":-0.29059360450763,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906767,"numValue":0.143548225010791,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463215,"numValue":5.0,"position":279,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465188 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,188 | train | mutant | 5,058,563 | 5,064,797 | 5,065,231 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S279I | S279I | 1 | 1 | 0 | 0 | 279 | S | I | 5 | CONSERVATION | null | false | false | null | null | 5,457,043 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.393669 | 0.139136 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906768,"numValue":-0.393669166887877,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906769,"numValue":0.139135973799451,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463215,"numValue":5.0,"position":279,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465189 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,189 | train | mutant | 5,058,564 | 5,064,797 | 5,065,232 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S279K | S279K | 1 | 1 | 0 | 0 | 279 | S | K | 5 | CONSERVATION | null | false | false | null | null | 5,457,044 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.031372 | 0.07555 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906770,"numValue":0.0313722359580371,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906771,"numValue":0.0755497085134225,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463215,"numValue":5.0,"position":279,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465190 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,190 | train | mutant | 5,058,565 | 5,064,797 | 5,065,233 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S279L | S279L | 1 | 1 | 0 | 0 | 279 | S | L | 5 | CONSERVATION | null | false | false | null | null | 5,457,045 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.163274 | 0.082796 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906772,"numValue":-0.16327436965621,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906773,"numValue":0.0827963691403109,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463215,"numValue":5.0,"position":279,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465191 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,191 | train | mutant | 5,058,566 | 5,064,797 | 5,065,234 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S279M | S279M | 1 | 1 | 0 | 0 | 279 | S | M | 5 | CONSERVATION | null | false | false | null | null | 5,457,046 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.269382 | 0.109381 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906774,"numValue":-0.269381879017847,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906775,"numValue":0.109381329120721,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463215,"numValue":5.0,"position":279,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465192 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,192 | train | mutant | 5,058,567 | 5,064,797 | 5,065,235 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S279N | S279N | 1 | 1 | 0 | 0 | 279 | S | N | 5 | CONSERVATION | null | false | false | null | null | 5,457,047 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.130444 | 0.132258 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906776,"numValue":-0.130444457498593,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906777,"numValue":0.13225845454696,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463215,"numValue":5.0,"position":279,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465193 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,193 | train | mutant | 5,058,568 | 5,064,797 | 5,065,236 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S279P | S279P | 1 | 1 | 0 | 0 | 279 | S | P | 5 | CONSERVATION | null | false | false | null | null | 5,457,048 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.042751 | 0.082901 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906778,"numValue":-0.0427506963593129,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906779,"numValue":0.0829012652368416,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463215,"numValue":5.0,"position":279,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465194 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,194 | train | mutant | 5,058,569 | 5,064,797 | 5,065,237 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S279Q | S279Q | 1 | 1 | 0 | 0 | 279 | S | Q | 5 | CONSERVATION | null | false | false | null | null | 5,457,049 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.120792 | 0.14732 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906780,"numValue":-0.120791987189056,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906781,"numValue":0.147320035353721,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463215,"numValue":5.0,"position":279,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465195 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,195 | train | mutant | 5,058,570 | 5,064,797 | 5,065,238 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S279R | S279R | 1 | 1 | 0 | 0 | 279 | S | R | 5 | CONSERVATION | null | false | false | null | null | 5,457,050 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.159095 | 0.045874 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906782,"numValue":-0.159094527059823,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906783,"numValue":0.0458742505819198,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463215,"numValue":5.0,"position":279,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465196 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,196 | train | mutant | 5,058,871 | 5,064,797 | 5,065,539 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S279T | S279T | 1 | 1 | 0 | 0 | 279 | S | T | 5 | CONSERVATION | null | false | false | null | null | 5,457,351 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.097777 | 0.070257 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907384,"numValue":0.0977765093631512,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907385,"numValue":0.0702573194377211,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463215,"numValue":5.0,"position":279,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465198 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,198 | train | mutant | 5,058,873 | 5,064,797 | 5,065,541 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S279W | S279W | 1 | 1 | 0 | 0 | 279 | S | W | 5 | CONSERVATION | null | false | false | null | null | 5,457,353 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.286711 | 0.086866 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907388,"numValue":-0.286711443978507,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907389,"numValue":0.0868658810642425,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463215,"numValue":5.0,"position":279,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465199 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,199 | train | mutant | 5,058,874 | 5,064,797 | 5,065,542 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S279Y | S279Y | 1 | 1 | 0 | 0 | 279 | S | Y | 5 | CONSERVATION | null | false | false | null | null | 5,457,354 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.604684 | 0.198863 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907390,"numValue":-0.604684090748042,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907391,"numValue":0.198863426743408,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463215,"numValue":5.0,"position":279,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465200 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,200 | train | mutant | 5,058,571 | 5,064,797 | 5,065,239 | 743 | 742 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | delH280 | delH280 | 1 | 0 | 1 | 0 | 280 | H | - | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,051 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.792681 | 0.205409 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906784,"numValue":-0.79268060972166,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906785,"numValue":0.205409310025192,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6097,"numValue":null,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463216,"numValue":9.0,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465201 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,201 | train | mutant | 5,058,572 | 5,064,797 | 5,065,240 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H280A | H280A | 1 | 1 | 0 | 0 | 280 | H | A | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,052 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.185521 | 0.073113 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906786,"numValue":-0.185521006220221,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906787,"numValue":0.0731133305608052,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6097,"numValue":null,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463216,"numValue":9.0,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465202 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,202 | train | mutant | 5,058,573 | 5,064,797 | 5,065,241 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H280C | H280C | 1 | 1 | 0 | 0 | 280 | H | C | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,053 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.366401 | 0.110923 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906788,"numValue":-0.366400865086918,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906789,"numValue":0.110922816823343,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6097,"numValue":null,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463216,"numValue":9.0,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465203 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,203 | train | mutant | 5,058,574 | 5,064,797 | 5,065,242 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H280D | H280D | 1 | 1 | 0 | 0 | 280 | H | D | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,054 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.200382 | 0.084529 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906790,"numValue":-0.200381693098272,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906791,"numValue":0.0845292085539513,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6097,"numValue":null,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463216,"numValue":9.0,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465204 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,204 | train | mutant | 5,058,575 | 5,064,797 | 5,065,243 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H280E | H280E | 1 | 1 | 0 | 0 | 280 | H | E | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,055 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.19823 | 0.081039 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906792,"numValue":-0.198230303526602,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906793,"numValue":0.0810391863390001,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6097,"numValue":null,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463216,"numValue":9.0,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465205 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,205 | train | mutant | 5,058,576 | 5,064,797 | 5,065,244 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H280F | H280F | 1 | 1 | 0 | 0 | 280 | H | F | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,056 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.514097 | 0.136129 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906794,"numValue":-0.514097027733102,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906795,"numValue":0.136128809264828,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6097,"numValue":null,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463216,"numValue":9.0,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465206 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,206 | train | mutant | 5,058,577 | 5,064,797 | 5,065,245 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H280G | H280G | 1 | 1 | 0 | 0 | 280 | H | G | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,057 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.164827 | 0.0871 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906796,"numValue":-0.164826687483206,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906797,"numValue":0.0871001239705311,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6097,"numValue":null,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463216,"numValue":9.0,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465207 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,207 | train | mutant | 5,058,858 | 5,064,797 | 5,065,526 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H280I | H280I | 1 | 1 | 0 | 0 | 280 | H | I | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,338 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.366241 | 0.094271 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907358,"numValue":-0.366240852438504,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907359,"numValue":0.0942708078600291,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6097,"numValue":null,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463216,"numValue":9.0,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465208 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,208 | train | mutant | 5,058,859 | 5,064,797 | 5,065,527 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H280K | H280K | 1 | 1 | 0 | 0 | 280 | H | K | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,339 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.11728 | 0.103843 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907360,"numValue":-0.117279514418982,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907361,"numValue":0.103842549837067,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6097,"numValue":null,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463216,"numValue":9.0,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465209 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,209 | train | mutant | 5,058,860 | 5,064,797 | 5,065,528 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H280L | H280L | 1 | 1 | 0 | 0 | 280 | H | L | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,340 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.418515 | 0.077817 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907362,"numValue":-0.418514935733054,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907363,"numValue":0.0778166584392277,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6097,"numValue":null,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463216,"numValue":9.0,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465210 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,210 | train | mutant | 5,058,861 | 5,064,797 | 5,065,529 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H280M | H280M | 1 | 1 | 0 | 0 | 280 | H | M | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,341 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.16965 | 0.073486 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907364,"numValue":-0.169650483420774,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907365,"numValue":0.0734862576002989,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6097,"numValue":null,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463216,"numValue":9.0,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465211 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,211 | train | mutant | 5,058,862 | 5,064,797 | 5,065,530 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H280N | H280N | 1 | 1 | 0 | 0 | 280 | H | N | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,342 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.316088 | 0.140915 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907366,"numValue":-0.316087912422326,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907367,"numValue":0.140914650982741,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6097,"numValue":null,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463216,"numValue":9.0,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465212 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,212 | train | mutant | 5,058,863 | 5,064,797 | 5,065,531 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H280P | H280P | 1 | 1 | 0 | 0 | 280 | H | P | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,343 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.270157 | 0.092509 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907368,"numValue":-0.270156964675776,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907369,"numValue":0.0925091954402806,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6097,"numValue":null,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463216,"numValue":9.0,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465213 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,213 | train | mutant | 5,058,864 | 5,064,797 | 5,065,532 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H280Q | H280Q | 1 | 1 | 0 | 0 | 280 | H | Q | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,344 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.330886 | 0.127629 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907370,"numValue":-0.330886057771332,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907371,"numValue":0.127629210573379,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6097,"numValue":null,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463216,"numValue":9.0,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465214 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,214 | train | mutant | 5,058,865 | 5,064,797 | 5,065,533 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H280R | H280R | 1 | 1 | 0 | 0 | 280 | H | R | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,345 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.188619 | 0.075917 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907372,"numValue":-0.188618812066049,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907373,"numValue":0.0759165472667814,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6097,"numValue":null,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463216,"numValue":9.0,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465216 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,216 | train | mutant | 5,058,867 | 5,064,797 | 5,065,535 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H280T | H280T | 1 | 1 | 0 | 0 | 280 | H | T | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,347 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.219407 | 0.073155 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907376,"numValue":-0.219406611582621,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907377,"numValue":0.0731545435746408,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6097,"numValue":null,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463216,"numValue":9.0,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465217 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,217 | train | mutant | 5,058,868 | 5,064,797 | 5,065,536 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H280V | H280V | 1 | 1 | 0 | 0 | 280 | H | V | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,348 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.226933 | 0.076139 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907378,"numValue":-0.226933060179384,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907379,"numValue":0.0761390331461591,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6097,"numValue":null,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463216,"numValue":9.0,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465218 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,218 | train | mutant | 5,058,869 | 5,064,797 | 5,065,537 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H280W | H280W | 1 | 1 | 0 | 0 | 280 | H | W | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,349 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.427055 | 0.161534 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907380,"numValue":-0.427054830292671,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907381,"numValue":0.161533744261263,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6097,"numValue":null,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463216,"numValue":9.0,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465219 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,219 | train | mutant | 5,058,870 | 5,064,797 | 5,065,538 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | H280Y | H280Y | 1 | 1 | 0 | 0 | 280 | H | Y | 9 | BINDING_SITE|CONSERVATION | null | false | false | null | null | 5,457,350 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.53803 | 0.124864 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907382,"numValue":-0.538029651226748,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907383,"numValue":0.124863821247763,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":6097,"numValue":null,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"BINDING_SITE"},{"id":1463216,"numValue":9.0,"position":280,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465221 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,221 | train | mutant | 5,058,579 | 5,064,797 | 5,065,247 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S281A | S281A | 1 | 1 | 0 | 0 | 281 | S | A | 7 | CONSERVATION | null | false | false | null | null | 5,457,059 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.348916 | 0.054191 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906800,"numValue":-0.348915873206182,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906801,"numValue":0.0541913958267008,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463217,"numValue":7.0,"position":281,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465222 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,222 | train | mutant | 5,058,580 | 5,064,797 | 5,065,248 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S281C | S281C | 1 | 1 | 0 | 0 | 281 | S | C | 7 | CONSERVATION | null | false | false | null | null | 5,457,060 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.102584 | 0.074092 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906802,"numValue":-0.102583718623748,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906803,"numValue":0.0740918957176788,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463217,"numValue":7.0,"position":281,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465223 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,223 | train | mutant | 5,058,581 | 5,064,797 | 5,065,249 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S281D | S281D | 1 | 1 | 0 | 0 | 281 | S | D | 7 | CONSERVATION | null | false | false | null | null | 5,457,061 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.043584 | 0.055963 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906804,"numValue":0.0435839329553247,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906805,"numValue":0.0559627260877799,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463217,"numValue":7.0,"position":281,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465224 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,224 | train | mutant | 5,058,582 | 5,064,797 | 5,065,250 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S281E | S281E | 1 | 1 | 0 | 0 | 281 | S | E | 7 | CONSERVATION | null | false | false | null | null | 5,457,062 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.027577 | 0.064364 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906806,"numValue":-0.0275768139925969,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906807,"numValue":0.0643636633218649,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463217,"numValue":7.0,"position":281,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465225 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,225 | train | mutant | 5,058,583 | 5,064,797 | 5,065,251 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S281F | S281F | 1 | 1 | 0 | 0 | 281 | S | F | 7 | CONSERVATION | null | false | false | null | null | 5,457,063 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.455295 | 0.119 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906808,"numValue":-0.455294623520619,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906809,"numValue":0.11899955282075,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463217,"numValue":7.0,"position":281,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465226 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,226 | train | mutant | 5,058,584 | 5,064,797 | 5,065,252 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S281G | S281G | 1 | 1 | 0 | 0 | 281 | S | G | 7 | CONSERVATION | null | false | false | null | null | 5,457,064 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.220055 | 0.045669 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906810,"numValue":-0.220055443358204,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906811,"numValue":0.0456694148782117,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463217,"numValue":7.0,"position":281,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465227 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,227 | train | mutant | 5,058,585 | 5,064,797 | 5,065,253 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S281H | S281H | 1 | 1 | 0 | 0 | 281 | S | H | 7 | CONSERVATION | null | false | false | null | null | 5,457,065 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.091356 | 0.150522 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906812,"numValue":-0.0913564896889618,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906813,"numValue":0.150521654283643,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463217,"numValue":7.0,"position":281,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465228 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,228 | train | mutant | 5,058,586 | 5,064,797 | 5,065,254 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S281I | S281I | 1 | 1 | 0 | 0 | 281 | S | I | 7 | CONSERVATION | null | false | false | null | null | 5,457,066 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.249612 | 0.076153 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906814,"numValue":-0.24961192603149,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906815,"numValue":0.0761529561979449,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463217,"numValue":7.0,"position":281,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465229 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,229 | train | mutant | 5,058,587 | 5,064,797 | 5,065,255 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S281K | S281K | 1 | 1 | 0 | 0 | 281 | S | K | 7 | CONSERVATION | null | false | false | null | null | 5,457,067 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.038372 | 0.086809 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906816,"numValue":0.0383718136392882,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906817,"numValue":0.0868086472718279,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463217,"numValue":7.0,"position":281,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465230 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,230 | train | mutant | 5,058,588 | 5,064,797 | 5,065,256 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S281L | S281L | 1 | 1 | 0 | 0 | 281 | S | L | 7 | CONSERVATION | null | false | false | null | null | 5,457,068 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.332514 | 0.086484 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906818,"numValue":-0.332514381606326,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906819,"numValue":0.086484250897774,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463217,"numValue":7.0,"position":281,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465231 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,231 | train | mutant | 5,058,589 | 5,064,797 | 5,065,257 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S281M | S281M | 1 | 1 | 0 | 0 | 281 | S | M | 7 | CONSERVATION | null | false | false | null | null | 5,457,069 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.322005 | 0.07897 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906820,"numValue":-0.322005160646955,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906821,"numValue":0.078969891061462,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463217,"numValue":7.0,"position":281,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465232 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,232 | train | mutant | 5,058,590 | 5,064,797 | 5,065,258 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S281N | S281N | 1 | 1 | 0 | 0 | 281 | S | N | 7 | CONSERVATION | null | false | false | null | null | 5,457,070 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.028867 | 0.058476 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906822,"numValue":0.0288666720487182,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906823,"numValue":0.0584763394138636,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463217,"numValue":7.0,"position":281,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465233 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,233 | train | mutant | 5,058,591 | 5,064,797 | 5,065,259 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S281P | S281P | 1 | 1 | 0 | 0 | 281 | S | P | 7 | CONSERVATION | null | false | false | null | null | 5,457,071 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.172247 | 0.072357 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906824,"numValue":-0.172246786209986,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906825,"numValue":0.0723571244440149,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463217,"numValue":7.0,"position":281,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465234 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,234 | train | mutant | 5,058,592 | 5,064,797 | 5,065,260 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S281Q | S281Q | 1 | 1 | 0 | 0 | 281 | S | Q | 7 | CONSERVATION | null | false | false | null | null | 5,457,072 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.031445 | 0.113416 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906826,"numValue":-0.0314454124740802,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906827,"numValue":0.113415696803214,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463217,"numValue":7.0,"position":281,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465235 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,235 | train | mutant | 5,058,593 | 5,064,797 | 5,065,261 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S281R | S281R | 1 | 1 | 0 | 0 | 281 | S | R | 7 | CONSERVATION | null | false | false | null | null | 5,457,073 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.11802 | 0.053309 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906828,"numValue":-0.11802006076134,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906829,"numValue":0.0533087699607943,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463217,"numValue":7.0,"position":281,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465237 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,237 | train | mutant | 5,058,855 | 5,064,797 | 5,065,523 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S281V | S281V | 1 | 1 | 0 | 0 | 281 | S | V | 7 | CONSERVATION | null | false | false | null | null | 5,457,335 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.199285 | 0.05094 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907352,"numValue":-0.199285021044505,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907353,"numValue":0.0509401534620331,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463217,"numValue":7.0,"position":281,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465238 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,238 | train | mutant | 5,058,856 | 5,064,797 | 5,065,524 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S281W | S281W | 1 | 1 | 0 | 0 | 281 | S | W | 7 | CONSERVATION | null | false | false | null | null | 5,457,336 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.050508 | 0.094808 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907354,"numValue":-0.0505083827467719,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907355,"numValue":0.0948078356759669,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463217,"numValue":7.0,"position":281,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465239 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,239 | train | mutant | 5,058,857 | 5,064,797 | 5,065,525 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | S281Y | S281Y | 1 | 1 | 0 | 0 | 281 | S | Y | 7 | CONSERVATION | null | false | false | null | null | 5,457,337 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.569621 | 0.099465 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907356,"numValue":-0.569621221595538,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907357,"numValue":0.0994647403726115,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463217,"numValue":7.0,"position":281,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465240 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,240 | train | mutant | 5,058,594 | 5,064,797 | 5,065,262 | 743 | 742 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | delN282 | delN282 | 1 | 0 | 1 | 0 | 282 | N | - | 6 | CONSERVATION | null | false | false | null | null | 5,457,074 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.651321 | 0.59502 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906830,"numValue":-1.65132116504302,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906831,"numValue":0.595020107333314,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463218,"numValue":6.0,"position":282,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465241 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,241 | train | mutant | 5,058,595 | 5,064,797 | 5,065,263 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | N282A | N282A | 1 | 1 | 0 | 0 | 282 | N | A | 6 | CONSERVATION | null | false | false | null | null | 5,457,075 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.006671 | 0.05912 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906832,"numValue":0.00667077120249741,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906833,"numValue":0.0591204391080757,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463218,"numValue":6.0,"position":282,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465242 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,242 | train | mutant | 5,058,596 | 5,064,797 | 5,065,264 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | N282C | N282C | 1 | 1 | 0 | 0 | 282 | N | C | 6 | CONSERVATION | null | false | false | null | null | 5,457,076 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.062938 | 0.086529 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906834,"numValue":-0.062937657918428,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906835,"numValue":0.0865288397882163,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463218,"numValue":6.0,"position":282,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465244 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,244 | train | mutant | 5,058,598 | 5,064,797 | 5,065,266 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | N282E | N282E | 1 | 1 | 0 | 0 | 282 | N | E | 6 | CONSERVATION | null | false | false | null | null | 5,457,078 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.166534 | 0.121897 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906838,"numValue":-0.166534139524214,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906839,"numValue":0.121896659875244,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463218,"numValue":6.0,"position":282,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465245 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,245 | train | mutant | 5,058,599 | 5,064,797 | 5,065,267 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | N282F | N282F | 1 | 1 | 0 | 0 | 282 | N | F | 6 | CONSERVATION | null | false | false | null | null | 5,457,079 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.274046 | 0.079844 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906840,"numValue":-0.274046345287816,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906841,"numValue":0.0798442235888836,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463218,"numValue":6.0,"position":282,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465246 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,246 | train | mutant | 5,058,600 | 5,064,797 | 5,065,268 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | N282G | N282G | 1 | 1 | 0 | 0 | 282 | N | G | 6 | CONSERVATION | null | false | false | null | null | 5,457,080 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.045042 | 0.051741 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906842,"numValue":-0.0450416091549052,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906843,"numValue":0.0517414753401812,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463218,"numValue":6.0,"position":282,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465247 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,247 | train | mutant | 5,058,601 | 5,064,797 | 5,065,269 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | N282H | N282H | 1 | 1 | 0 | 0 | 282 | N | H | 6 | CONSERVATION | null | false | false | null | null | 5,457,081 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.174183 | 0.08282 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906844,"numValue":-0.174182548981049,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906845,"numValue":0.0828196978136255,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463218,"numValue":6.0,"position":282,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465248 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,248 | train | mutant | 5,058,602 | 5,064,797 | 5,065,270 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | N282I | N282I | 1 | 1 | 0 | 0 | 282 | N | I | 6 | CONSERVATION | null | false | false | null | null | 5,457,082 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.176935 | 0.102036 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906846,"numValue":-0.176934961671153,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906847,"numValue":0.102036163146369,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463218,"numValue":6.0,"position":282,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465249 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,249 | train | mutant | 5,058,603 | 5,064,797 | 5,065,271 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | N282K | N282K | 1 | 1 | 0 | 0 | 282 | N | K | 6 | CONSERVATION | null | false | false | null | null | 5,457,083 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.248493 | 0.133693 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906848,"numValue":-0.248492813179469,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906849,"numValue":0.133692811830094,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463218,"numValue":6.0,"position":282,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465250 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,250 | train | mutant | 5,058,604 | 5,064,797 | 5,065,272 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | N282L | N282L | 1 | 1 | 0 | 0 | 282 | N | L | 6 | CONSERVATION | null | false | false | null | null | 5,457,084 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.21976 | 0.064828 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906850,"numValue":-0.21975981023339,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906851,"numValue":0.0648278658690365,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463218,"numValue":6.0,"position":282,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465251 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,251 | train | mutant | 5,058,605 | 5,064,797 | 5,065,273 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | N282M | N282M | 1 | 1 | 0 | 0 | 282 | N | M | 6 | CONSERVATION | null | false | false | null | null | 5,457,085 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.149242 | 0.058196 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12906852,"numValue":-0.149242040939768,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12906853,"numValue":0.0581958684631732,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463218,"numValue":6.0,"position":282,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465252 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,252 | train | mutant | 5,058,846 | 5,064,797 | 5,065,514 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | N282P | N282P | 1 | 1 | 0 | 0 | 282 | N | P | 6 | CONSERVATION | null | false | false | null | null | 5,457,326 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.108251 | 0.094861 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907334,"numValue":0.108250508026133,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907335,"numValue":0.0948606105793372,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463218,"numValue":6.0,"position":282,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465253 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,253 | train | mutant | 5,058,847 | 5,064,797 | 5,065,515 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | N282Q | N282Q | 1 | 1 | 0 | 0 | 282 | N | Q | 6 | CONSERVATION | null | false | false | null | null | 5,457,327 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.084252 | 0.115624 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907336,"numValue":-0.0842515378246082,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907337,"numValue":0.115623773782645,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463218,"numValue":6.0,"position":282,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465254 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,254 | train | mutant | 5,058,848 | 5,064,797 | 5,065,516 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | N282R | N282R | 1 | 1 | 0 | 0 | 282 | N | R | 6 | CONSERVATION | null | false | false | null | null | 5,457,328 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.181544 | 0.054701 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907338,"numValue":-0.181544106494994,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907339,"numValue":0.054700577539067,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463218,"numValue":6.0,"position":282,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465256 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,256 | train | mutant | 5,058,850 | 5,064,797 | 5,065,518 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | N282T | N282T | 1 | 1 | 0 | 0 | 282 | N | T | 6 | CONSERVATION | null | false | false | null | null | 5,457,330 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.04189 | 0.080546 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907342,"numValue":-0.041890140530645,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907343,"numValue":0.0805457717266241,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463218,"numValue":6.0,"position":282,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465257 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,257 | train | mutant | 5,058,851 | 5,064,797 | 5,065,519 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | N282V | N282V | 1 | 1 | 0 | 0 | 282 | N | V | 6 | CONSERVATION | null | false | false | null | null | 5,457,331 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.036952 | 0.062932 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907344,"numValue":0.0369521892280504,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907345,"numValue":0.0629324379936169,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463218,"numValue":6.0,"position":282,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5465258 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,465,258 | train | mutant | 5,058,852 | 5,064,797 | 5,065,520 | 743 | 743 | 8,260 | Dystrobrevin alpha | Homo sapiens | 1 | 8260 | Dystrobrevin alpha | Homo sapiens | 1 | Q9Y4J8 | IPR017432|IPR011992|IPR015153|IPR015154|IPR050774|IPR000433|IPR043145 | N282W | N282W | 1 | 1 | 0 | 0 | 282 | N | W | 6 | CONSERVATION | null | false | false | null | null | 5,457,332 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.531805 | 0.091999 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12907346,"numValue":-0.53180545190949,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12907347,"numValue":0.0919993600177044,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1463218,"numValue":6.0,"position":282,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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