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10.1261_rna.079608.123
Comparison of TRIBE and STAMP for identifying targets of RNA binding proteins in human and Drosophila cells KATHARINE C. ABRUZZI,1 CORRIE RATNER,1 and MICHAEL ROSBASH Howard Hughes Medical Institute, Brandeis University, Waltham, Massachusetts 02454, USA ABSTRACT RNA binding proteins (RBPs) perform a myriad of func...
10.1371_journal.pbio.3002472
RESEARCH ARTICLE Dynamics of bacterial recombination in the human gut microbiome Zhiru Liu1, Benjamin H. GoodID 1,2,3* 1 Department of Applied Physics, Stanford University, Stanford, California, United States of America, 2 Department of Biology, Stanford University, Stanford, California, United States of America, 3...
10.1371_journal.pcbi.1011739
RESEARCH ARTICLE Explaining the flaws in human random generation as local sampling with momentum Lucas CastilloID 1*, Pablo Leo´ n-Villagra´ ID 2, Nick Chater3, Adam Sanborn1 1 Department of Psychology, University of Warwick, Coventry, United Kingdom, 2 Cognitive, Linguistic & Psychological Sciences, Brown Univers...
10.1371_journal.pdig.0000467
RESEARCH ARTICLE Clinical gait analysis using video-based pose estimation: Multiple perspectives, clinical populations, and measuring change Jan StenumID 1,2, Melody M. Hsu1,3, Alexander Y. Pantelyat4, Ryan T. RoemmichID 1,2* a1111111111 a1111111111 a1111111111 a1111111111 a1111111111 OPEN ACCESS Citation: Stenu...
10.1126_science.abn5887
A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t HHS Public Access Author manuscript Science. Author manuscript; available in PMC 2023 May 15. Published in final edited form as: Science. 2023 April 28; 380(6643): eabn5887. doi:10.1...
10.1126_science.adh1720
A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t HHS Public Access Author manuscript Science. Author manuscript; available in PMC 2023 August 04. Published in final edited form as: Science. 2023 July 28; 381(6656): eadh1720. doi:10...
10.1371_journal.pbio.3002512
RESEARCH ARTICLE Cross-frequency coupling in cortico- hippocampal networks supports the maintenance of sequential auditory information in short-term memory Arthur Borderie1,2, Anne Caclin3, Jean-Philippe Lachaux3, Marcela Perrone-Bertollotti4, Roxane S. Hoyer1, Philippe Kahane5, He´ lène Catenoix3,6, Barbara Tillmann...
10.1371_journal.pbio.3002555
RESEARCH ARTICLE Specification of distinct cell types in a sensory- adhesive organ important for metamorphosis in tunicate larvae Christopher J. Johnson1☯, Florian Razy-Krajka1☯, Fan Zeng2, Katarzyna M. Piekarz1, Shweta Biliya3, Ute Rothba¨ cher2*, Alberto StolfiID 1* 1 School of Biological Sciences, Georgia Instit...
10.1371_journal.pclm.0000325
RESEARCH ARTICLE Climate change impact on Spodoptera frugiperda (Lepidoptera: Noctuidae) life cycle in Mozambique Telmo Cosme A. SumilaID 1*, Simone E. T. Ferraz1, Angelica Durigon2 1 Physics Department, Federal University of Santa Maria, Santa Maria, RS, Brazil, 2 Department of Plant Science, Federal University of...
10.1371_journal.pbio.3002514
RESEARCH ARTICLE Engineering of Cas12a nuclease variants with enhanced genome-editing specificity Peng Chen1☯, Jin Zhou1☯, Huan Liu1☯, Erchi Zhou2☯, Boxiao He1, Yankang Wu1, Hongjian Wang1, Zaiqiao Sun1, Chonil Paek1,3, Jun Lei1, Yongshun Chen1*, Xinghua Zhang2*, Lei YinID 1* 1 State Key Laboratory of Virology, Hub...
10.1126_science.add6162
H H M I A u t h o r M a n u s c r i p t H H M I A u t h o r M a n u s c r i p t H H M I A u t h o r M a n u s c r i p t Published as: Science. 2023 July 07; 381(6653): 54–59. Cortical polarity ensures its own asymmetric inheritance in the stomatal lineage to pattern the leaf surface Andrew Muroyama1,2,*, ...
10.1093_nar_gkad331
Published online 1 May 2023 Nucleic Acids Research, 2023, Vol. 51, Web Server issue W419–W426 https://doi.org/10.1093/nar/gkad331 PANGEA: a new gene set enrichment tool for Drosophila and common research organisms Yanhui Hu 1 , 2 ,* , Aram Comjean 1 , 2 , Helen Attrill 3 , Giulia Antonazzo 3 , Jim Thurm...
10.1093_hmg_ddad091
Human Molecular Genetics, 2023, Vol. 32, 16, 2600–2610 https://doi.org/10.1093/hmg/ddad091 Advance access publication date 1 June 2023 Original Article Continuous, but not intermittent, regimens of hypoxia prevent and reverse ataxia in a murine model of Friedreich’s ataxia Tslil Ast 1,2,3,4,†,‡, Hong Wang1,2,3,4,‡,...
10.1126_sciadv.adg1671
S C I E N C E A D VA N C E S | R E S E A R C H A R T I C L E D E V E LO P M E N TA L B I O LO G Y Atoh1 drives the heterogeneity of the pontine nuclei neurons and promotes their differentiation Sih-Rong Wu1,2, Jessica C. Butts2,3,4, Matthew S. Caudill1,2, Jean-Pierre Revelli2,3, Ryan S. Dhindsa2,3, Mark A. Durham2,5,6...
10.1126_science.adg6518
A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t HHS Public Access Author manuscript Science. Author manuscript; available in PMC 2023 June 15. Published in final edited form as: Science. 2023 April 21; 380(6642): eadg6518. doi:10....
10.1093_nar_gkad501
7438–7450 Nucleic Acids Research, 2023, Vol. 51, No. 14 https://doi.org/10.1093/nar/gkad501 Published online 9 June 2023 Rarely acquired type II-A CRISPR-Cas spacers mediate anti-viral immunity through the targeting of a non-canonical PAM sequence Claire T. K enne y 1 and Luciano A. Marraffini 1 , 2 , ...
10.1126_scitranslmed.adh9917
A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t HHS Public Access Author manuscript Sci Transl Med. Author manuscript; available in PMC 2023 September 14. Published in final edited form as: Sci Transl Med. 2023 July 26; 15(706): e...
10.1093_mnras_stab3539
Downloaded from orbit.dtu.dk on: Mar 07, 2025 Rapid build-up of the stellar content in the protocluster core SPT2349−56 at z = 4.3 Chapman, Ryley Hill Scott; Phadke, Kedar A.; Aravena, Manuel; Archipley, Melanie; Ashby, Matthew L N; Béthermin, Matthieu; Canning, Rebecca E A; Gonzalez, Anthony; Greve, Thomas R; Gurura...
10.1371_journal.pcbi.1011928
RESEARCH ARTICLE HormoneBayes: A novel Bayesian framework for the analysis of pulsatile hormone dynamics Margaritis VoliotisID 1 S. Dhillo2, Krasimira Tsaneva-AtanasovaID 1*, Ali Abbara2, Julia K. Prague2,3,4, Johannes D. Veldhuis5, Waljit 1 Department of Mathematics and Living Systems Institute, College of Enginee...
10.1093_nar_gkad439
6528–6539 Nucleic Acids Research, 2023, Vol. 51, No. 13 https://doi.org/10.1093/nar/gkad439 Published online 30 May 2023 NAR Breakthrough Article Enhanced nonenzymatic RNA copying with in-situ activation of short oligonucleotides Dian Ding 1 , 2 , † , Stephanie J. Zhang 1 , 2 , † and Jack W. Szostak 1 , 2...
10.1126_science.adc9498
A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t HHS Public Access Author manuscript Science. Author manuscript; available in PMC 2023 June 16. Published in final edited form as: Science. 2023 April 07; 380(6640): eadc9498. doi:10....
10.1128_mbio.01039-23
| Bacteriology | Research Article Structural disruption of Ntox15 nuclease effector domains by immunity proteins protects against type VI secretion system intoxication in Bacteroidales Dustin E. Bosch,1 Romina Abbasian,1 Bishal Parajuli,1 S. Brook Peterson,2,3 Joseph D. Mougous2,3,4 AUTHOR AFFILIATIONS See affilia...
10.1128_mbio.00782-23
| Editor’s Pick | Virology | Research Article APOBEC3 degradation is the primary function of HIV-1 Vif determining virion infectivity in the myeloid cell line THP-1 Terumasa Ikeda,1 Ryo Shimizu,1,2 Hesham Nasser,1,3 Michael A. Carpenter,4,5 Adam Z. Cheng,6,7 William L. Brown,6,7 Daniel Sauter,8 Reuben S. Harris4,5 ...
10.1093_ijrl_eeac041
Utterly unbelievable: the discourse of ‘fake’ SOGI asylum claims as a form of Utterly unbelievable: the discourse of ‘fake’ SOGI asylum claims as a form of epistemic injustice epistemic injustice Nuno Ferreira Publication date Publication date 01-02-2023 Licence Licence This work is made available under the CC BY 4....
10.1126_science.adg7883
A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t HHS Public Access Author manuscript Science. Author manuscript; available in PMC 2023 September 13. Published in final edited form as: Science. 2023 April 21; 380(6642): 301–308. doi...
10.1371_journal.pbio.3002483
RESEARCH ARTICLE GABAergic regulation of striatal spiny projection neurons depends upon their activity state Michelle Day1, Marziyeh Belal1, William C. Surmeier1, Alexandria Melendez2, David Wokosin1, Tatiana Tkatch1,3, Vernon R. J. ClarkeID 1,3, D. James SurmeierID 1,3* a1111111111 a1111111111 a1111111111 a111111...
10.1371_journal.pgen.1011003
RESEARCH ARTICLE Kombucha Tea-associated microbes remodel host metabolic pathways to suppress lipid accumulation Rachel N. DuMez-KornegayID M. DeLoachID 2, Robert H. DowenID 1, Lillian S. BakerID 1,2,3,4* 2, Alexis J. Morris2, Whitney L. a1111111111 a1111111111 a1111111111 a1111111111 a1111111111 OPEN ACCESS Ci...
10.1128_jvi.00781-23
| Virology | Full-Length Text Human cytomegalovirus mediates APOBEC3B relocalization early during infection through a ribonucleotide reductase- independent mechanism Elisa Fanunza,1,2 Adam Z. Cheng,3 Ashley A. Auerbach,1 Bojana Stefanovska,1,4 Sofia N. Moraes,3 James R. Lokensgard,5 Matteo Biolatti,6...
10.1371_journal.pbio.3002093
RESEARCH ARTICLE Fibroblast-induced mammary epithelial branching depends on fibroblast contractility Jakub Sumbal1,2,3, Silvia Fre2, Zuzana Sumbalova KoledovaID 1¤* 1 Masaryk University, Faculty of Medicine, Department of Histology and Embryology, Brno, Czech Republic, 2 Institut Curie, Laboratory of Genetics and D...
10.1099_mgen.0.001019
SHORT COMMUNICATION Narunsky et al., Microbial Genomics 2023;9:001019 DOI 10.1099/mgen.0.001019 A conserved uORF in the ilvBNC mRNA of Corynebacterium species regulates ilv operon expression Aya Narunsky1†, Kumari Kavita1†, Shanker S. S. Panchapakesan1†, Megan E. Fris2‡ and Ronald R. Breaker1,2,3,* Abstract Computa...
10.1093_nar_gkad633
Published online 31 July 2023 Nucleic Acids Research, 2023, Vol. 51, No. 17 8957–8969 https://doi.org/10.1093/nar/gkad633 Linking folding dynamics and function of SAM / SAH riboswitches at the single molecule level Ting-Wei Liao 1 , Lin Huang 2 , Timothy J. Wilson 3 , Laura R. Ganser 1 , David M.J. Lill...
10.1126_sciadv.aat9488
M A T E R I A L S C I E N C E Nanoscale strain engineering of giant pseudo-magnetic fields, valley polarization, and topological channels in graphene C.-C. Hsu1*, M. L. Teague1*, J.-Q. Wang1*, N.-C. Yeh1,2† The existence of nontrivial Berry phases associated with two inequivalent valleys in graphene provides intere...
10.1126_science.add5327
A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t HHS Public Access Author manuscript Science. Author manuscript; available in PMC 2023 July 03. Published in final edited form as: Science. 2023 May 12; 380(6645): eadd5327. doi:10.11...
10.1126_sciimmunol.ade2860
A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t HHS Public Access Author manuscript Sci Immunol. Author manuscript; available in PMC 2023 July 21. Published in final edited form as: Sci Immunol. 2023 April 21; 8(82): eade2860. doi...
10.1093_molbev_msad085
Evolution of the SARS-CoV-2 Mutational Spectrum Jesse D. Bloom ,*,1,2,3 Annabel C. Beichman,2 Richard A. Neher ,4,5 and Kelley Harris2 1Basic Sciences Division and Computational Biology Program, Fred Hutchinson Cancer Center, Seattle, WA 2Department of Genome Sciences, University of Washington, Seattle, WA 3Howa...
10.1093_nar_gkad329
Published online 5 May 2023 Nucleic Acids Research, 2023, Vol. 51, No. 12 6355–6369 https://doi.org/10.1093/nar/gkad329 Translational fidelity screens in mammalian cells reveal eIF3 and eIF4G2 as regulators of start codon selectivity Richard She 1 ,* , Jingchuan Luo 1 and Jonathan S. Weissman 1 , 2 , 3...
10.1093_nar_gkad460
Published online 1 June 2023 Nucleic Acids Research, 2023, Vol. 51, No. 13 e69 https://doi.org/10.1093/nar/gkad460 A method to generate capture baits for targeted sequencing Balaji Sundararaman 1 , 3 ,* , Alisa O. Vershinina 2 , Samantha Hershauer 1 , 3 , Joshua D. Kapp 2 , Shelby Dunn 2 , Beth Shapiro 1 ,...
10.1371_journal.pcbi.1011899
RESEARCH ARTICLE Tipping points emerge from weak mutualism in metacommunities Jonas DenkID 1,2, Oskar HallatschekID 1,2,3* 1 Department of Physics, University of California, Berkeley, California, United States of America, 2 Department of Integrative Biology, University of California, Berkeley, California, United S...
10.1126_science.adf4197
A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t HHS Public Access Author manuscript Science. Author manuscript; available in PMC 2023 September 05. Published in final edited form as: Science. 2023 July 21; 381(6655): 319–324. doi:...
10.1073_pnas.2300360120
RESEARCH ARTICLE | MICROBIOLOGY OPEN ACCESS Structure-based design of a SARS-CoV-2 Omicron-specific inhibitor Kailu Yanga,b,c,d,e Tomas Kirchhausenf,g,h , Richard A. Pfuetznera,b,c,d,e, Luis Esquiviesa,b,c,d,e, , Chuchu Wanga,b,c,d,e, Alex J. B. Kreutzbergerf,g , and Axel T. Brungera,b,c,d,e,1 , K. Ian Whitea,b,...
10.1093_gbe_evad119
GBE Rapid Evolution of Glycan Recognition Receptors Reveals an Axis of Host–Microbe Arms Races beyond Canonical Protein–Protein Interfaces Zoë A. Hilbert Ellen M. Leffler 1,2,*, Paige E. Haffener1, Hannah J. Young1,2, Mara J.W. Schwiesow1,2, 1, and Nels C. Elde1,2,* 1Department of Human Genetics, University of Utah...
10.1093_gbe_evad099
GBE Automatic Differentiation is no Panacea for Phylogenetic Gradient Computation Mathieu Fourment Marc A. Suchard 1, Christiaan J. Swanepoel2,3, Jared G. Galloway4, Xiang Ji5, Karthik Gangavarapu6, 4,9,10,11,* 6,7,8,*, and Frederick A. Matsen IV 1Australian Institute for Microbiology and Infection, University of ...
10.1103_physrevd.103.104047
University of Southern Denmark Constraints on black-hole charges with the 2017 EHT observations of M87* Kocherlakota, Prashant; Rezzolla, Luciano; Falcke, Heino; Fromm, Christian M.; Kramer, Michael; Mizuno, Yosuke; Nathanail, Antonios; Olivares, Hector; Younsi, Ziri; Akiyama, Kazunori; Alberdi, Antxon; Alef, Walter;...
10.1073_pnas.2309151120
BRIEF REPORT | IMMUNOLOGY AND INFLAMMATION OPEN ACCESS Innate immune responses yield tissue- specific bottlenecks that scale with pathogen dose , Katherine G. Daileya,b Karthik Hullahallia,b,1 , and Matthew K. Waldora,b,c,1 Edited by Lawrence Steinman, Stanford University, Stanford, CA; received June 14, 2023; acc...
10.1073_pnas.2301121120
RESEARCH ARTICLE | BIOCHEMISTRY OPEN ACCESS Gβγ activates PIP2 hydrolysis by recruiting and orienting PLCβ on the membrane surface Maria E. Falzonea,b and Roderick MacKinnona,b,1 Edited by James Hurley, University of California, Berkeley, CA; received January 19, 2023; accepted April 6, 2023 Phospholipase C-βs ...
10.1093_beheco_arad033
Behavioral Ecology The official journal of the ISBE International Society for Behavioral Ecology Behavioral Ecology (2023), 34(4), 642–652. https://doi.org/10.1093/beheco/arad033 Original article Conditional indirect genetic effects of caregivers on brood in the clonal raider ant Patrick K. Piekarski,a, Stepha...
10.1073_pnas.2301852120
INAUGURAL ARTICLE | BIOPHYSICS AND COMPUTATIONAL BIOLOGY OPEN ACCESS Quantification of gallium cryo-FIB milling damage in biological lamellae Bronwyn A. Lucasa,1,2,3 and Nikolaus Grigorieff a,b,1 This contribution is part of the special series of Inaugural Articles by members of the National Academy of Sciences e...
10.1093_pnasnexus_pgad113
PNAS Nexus, 2023, 2, 1–13 https://doi.org/10.1093/pnasnexus/pgad113 Advance access publication 30 March 2023 Research Report Depicting pseudotime-lagged causality across single-cell trajectories for accurate gene-regulatory inference Caleb C. Reagor a,b,c,*, Nicolas Velez-Angel a and A. J. Hudspeth a aHoward Hug...
10.1073_pnas.2219624120
RESEARCH ARTICLE | NEUROSCIENCE OPEN ACCESS Structural basis for severe pain caused by mutations in the S4-S5 linkers of voltage-gated sodium channel NaV1.7 Goragot Wisedchaisria , Tamer M. Gamal El-Dina, Ning Zhenga,b,1 , and William A. Catteralla,1 Contributed by William A. Catterall; received November 16, 2022...
10.1073_pnas.2302191120
RESEARCH ARTICLE | IMMUNOLOGY AND INFLAMMATION OPEN ACCESS Circular RNA vaccine induces potent T cell responses Laura Amayaa,b,1 , Zhijian Lid, Audrey Leec, Paul A. Wenderd,e , Bali Pulendranc,2, and Howard Y. Changa,f,2 , Lilit Grigoryanc,1 Contributed by Howard Y. Chang; received February 9, 2023; accepted Apr...
10.1073_pnas.2221809120
RESEARCH ARTICLE | MEDICAL SCIENCES OPEN ACCESS Proxalutamide reduces SARS- CoV- 2 infection and associated inflammatory response Yuanyuan Qiaoa,b,c,1 Abhijit Paroliaa, Tongchen Hea, Caleb Chenga, Xuhong Caoa, Rui Wanga Qianxiang Zhoug, Liandong Mag, Jonathan Z. Sextond,e,h,i,j, and Arul M. Chinnaiyana,b,c,k,l,2 , C...
10.1073_pnas.2221064120
RESEARCH ARTICLE | BIOPHYSICS AND COMPUTATIONAL BIOLOGY EVOLUTION OPEN ACCESS Passive endocytosis in model protocells Stephanie J. Zhanga,b,1 and Anna Wangc,d,e,2 , Palapuravan Aneesf,g, Yamuna Krishnanf,g,h , Lauren A. Lowec,d,e , Thomas G. Faii,2 , Jack W. Szostaka,b,g,j,2 , Edited by Gerald Joyce, Salk Inst...
10.1073_pnas.2304730120
RESEARCH ARTICLE | GENETICS OPEN ACCESS split-intein Gal4 provides intersectional genetic labeling that is repressible by Gal80 Ben Ewen-Campena,1 and Norbert Perrimona,f,2 , Haojiang Luanb,1, Jun Xua,c,1, Rohit Singhd,1, Neha Joshia, Tanuj Thakkara, Bonnie Bergerd,e, Benjamin H. Whiteb , Contributed by Norbert P...
10.1073_pnas.2220537120
RESEARCH ARTICLE | BIOPHYSICS AND COMPUTATIONAL BIOLOGY OPEN ACCESS Multiple RNA- and DNA- binding proteins exhibit direct transfer of polynucleotides with implications for target- site search Wayne O. Hemphilla,b,c , James A. Goodricha, and Thomas R. Cecha,b,c,1 , Regan Fenskea,b,c , Calvin K. Voonga Edited by...
10.1073_pnas.2221163120
RESEARCH ARTICLE | EVOLUTION OPEN ACCESS Marginal specificity in protein interactions constrains evolution of a paralogous family Dia A. Ghosea , Kaitlyn E. Przydziala, Emily M. Mahoneya , and Michael T. Lauba,d,1 , Amy E. Keatinga,b,c Edited by William DeGrado, University of California San Francisco, San Franci...
10.1073_pnas.2217885120
RESEARCH ARTICLE | MEDICAL SCIENCES OPEN ACCESS Chromophore supply modulates cone function and survival in retinitis pigmentosa mouse models , Gayle B. Collinf, Vladimir J. Kefalovd,1,2 Yunlu Xuea,b,c,d,1 , Xiaomei Suna, Sean K. Wangb,c,e , and Constance L. Cepkob,c,e,1 Contributed by Constance L. Cepko; received...
10.1073_pnas.2301985120
RESEARCH ARTICLE | BIOCHEMISTRY OPEN ACCESS The membrane electric field regulates the PIP2-binding site to gate the KCNQ1 channel Venkata Shiva Mandalaa,b and Roderick MacKinnona,b,1 Edited by David Clapham, HHMI, Ashburn, VA; received February 3, 2023; accepted April 13, 2023 Voltage-dependent ion channels underl...
10.1103_physrevd.107.023530
Editors' Suggestion Featured in Physics PHYSICAL REVIEW D 107, 023530 (2023) Joint analysis of Dark Energy Survey Year 3 data and CMB lensing from SPT and Planck. II. Cross-correlation measurements and cosmological constraints C. Chang ,1,2 Y. Omori,1,2,3,4 E. J. Baxter,5 C. Doux,6 A. Choi,7 S. Pandey,6 A. Alarcon,...
10.1073_pnas.2302325120
RESEARCH ARTICLE | BIOCHEMISTRY OPEN ACCESS Membrane protein isolation and structure determination in cell-derived membrane vesicles Xiao Taoa,b,1 , and Roderick MacKinnona,b,2 , Chen Zhaoa,b,1 Edited by Donald Engelman, Yale University, New Haven, CT; received February 9, 2023; accepted March 27, 2023 Integral ...
10.1089_crispr.2023.0015
The CRISPR Journal Volume 6, Number 3, 2023 Mary Ann Liebert, Inc. DOI: 10.1089/crispr.2023.0015 RESEARCH ARTICLE The Transposon-Encoded Protein TnpB Processes Its Own mRNA into xRNA for Guided Nuclease Activity Suchita P. Nety,1–5 Han Altae-Tran,1–5 Soumya Kannan,1–5 F. Esra Demircioglu,1–5 Guilhem Faure,1–5 Seiichi...
10.1073_pnas.2221613120
RESEARCH ARTICLE | GENETICS OPEN ACCESS The retrotransposon R2 maintains Drosophila ribosomal DNA repeats Jonathan O. Nelsona,b,1, Alyssa Slickoa,b , and Yukiko M. Yamashitaa,b,c,1 Edited by R. Scott Hawley, Stowers Institute for Medical Research, Kansas City, MO; received December 20, 2022; accepted May 3, 2023 ...
10.1073_pnas.2306965120
RESEARCH ARTICLE | IMMUNOLOGY AND INFLAMMATION OPEN ACCESS IL- 6 trans- signaling in a humanized mouse model of scleroderma , Kriti Agrawalc,d, Esen Sefikb, Anahi V. Odellb, Elizabeth Cavese, Nancy C. Kirkiles- Smithb, Valerie Horsleya,e, Monique Hinchclifff, Ian D. Odella,b Jordan S. Pobera,b,g , Yuval Klugerc,d...
10.1073_pnas.2218085120
RESEARCH ARTICLE | BIOCHEMISTRY OPEN ACCESS In diverse conditions, intrinsic chromatin condensates have liquid-like material properties Bryan A. Gibsona,b,1, Claudia Blaukopfc, Tracy Loud, Lifeng Chena,b, Lynda K. Doolittlea,b, Ilya Finkelsteine,f,g and Michael K. Rosena,b,2 , Geeta J. Narlikard, Daniel W. Gerlichc...
10.1073_pnas.2108421118
BRCA1/Trp53 heterozygosity and replication stress drive esophageal cancer development in a mouse model Ye Hea,1, Joshua Riverab,1, Miklos Diossyc,d, Haohui Duanb, Christian Bowman-Colina, Rachel Reeda, Rebecca Jenningse, Jesse Novake, Stevenson V. Tranb, Elizabeth F. Cohena, David Szutsf, Anita Giobbie-Hurderg, Roder...
10.1073_pnas.2300099120
RESEARCH ARTICLE | IMMUNOLOGY AND INFLAMMATION OPEN ACCESS B cell peripheral tolerance is promoted by cathepsin B protease Marissa Y. Choua,b, Dan Liua,b, Jinping Ana,b, Ying Xua,b, and Jason G. Cystera,b,1 Contributed by Jason Cyster; received January 4, 2023; accepted March 14, 2023; reviewed by Robert Brink and ...
10.1073_pnas.2221652120
RESEARCH ARTICLE | IMMUNOLOGY AND INFLAMMATION OPEN ACCESS Enhanced inhibition of MHC-I expression by SARS-CoV-2 Omicron subvariants Miyu Moriyamaa, Carolina Lucasa, Valter Silva Monteiroa , Yale SARS-CoV-2 Genomic Surveillance Initiative1, and Akiko Iwasakia,b,c,2 Contributed by Akiko Iwasaki; received December 2...
10.1073_pnas.2221175120
RESEARCH ARTICLE | MEDICAL SCIENCES OPEN ACCESS Targeting SWI/SNF ATPases in H3.3K27M diffuse intrinsic pontine gliomas Mateus Motaa,b, Stefan R. Swehaa,b, Matt Puna,b,c,d, Siva Kumar Natarajana,b, Yujie Dinga,b, Chan Chunge Alexander R. Judkinsf, Susanta Samajdarg, Xuhong Caoh, Lanbo Xiaoh, Abhijit Paroliah, Arul M...
10.1021_acssynbio.3c00078
pubs.acs.org/synthbio This article is licensed under CC-BY 4.0 Research Article Tuning Methylation-Dependent Silencing Dynamics by Synthetic Modulation of CpG Density Yitong Ma, Mark W. Budde, Junqin Zhu, and Michael B. Elowitz* Cite This: ACS Synth. Biol. 2023, 12, 2536−2545 Read Online ACCESS Metrics & More A...
10.1073_pnas.2301987120
RESEARCH ARTICLE | MICROBIOLOGY OPEN ACCESS A role for the Gram- negative outer membrane in bacterial shape determination Elayne M. Fivensona , Andrea Vettigera, Marios F. Sardisa , Patricia D. A. Rohsa , Grasiela Torresa, Alison Forchoha, and Thomas G. Bernhardta,b,1 Edited by Thomas Silhavy, Princeton Universi...
10.1073_pnas.2305556120
RESEARCH ARTICLE | BIOCHEMISTRY OPEN ACCESS Changing protein–DNA interactions promote ORC binding- site exchange during replication origin licensing Annie Zhanga,b , and Stephen P. Bella,b,1 , Larry J. Friedmanc , Jeff Gellesc,1 Edited by James Berger, Johns Hopkins University, Baltimore, MD; received April 17, 2...
10.1073_pnas.2220576120
RESEARCH ARTICLE | GENETICS OPEN ACCESS Derepression of Y-linked multicopy protamine-like genes interferes with sperm nuclear compaction in D. melanogaster Jun I. Parka,b,c , and Yukiko M. Yamashitad,e,f,1 , George W. Belld Edited by Mariana Wolfner, Cornell University, Ithaca, NY; received December 3, 2022; acce...
10.1016_j.jmb.2023.168145
A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t HHS Public Access Author manuscript J Mol Biol. Author manuscript; available in PMC 2023 July 01. Published in final edited form as: J Mol Biol. 2023 July 01; 435(13): 168145. doi:10...
10.1084_jem.20221816
ARTICLE Dietary protein shapes the profile and repertoire of intestinal CD4+ T cells Ainsley Lockhart1, Aubrey Reed1, Tiago Rezende de Castro1, Calvin Herman1, Maria Cecilia Campos Canesso1, and Daniel Mucida1,2 The intestinal immune system must tolerate food antigens to avoid allergy, a process requiring CD4+...
10.1021_jacs.3c01003
pubs.acs.org/JACS Article Environmentally Ultrasensitive Fluorine Probe to Resolve Protein Conformational Ensembles by 19F NMR and Cryo-EM Yun Huang,* Krishna D. Reddy, Clay Bracken, Biao Qiu, Wenhu Zhan, David Eliezer,* and Olga Boudker* Cite This: J. Am. Chem. Soc. 2023, 145, 8583−8592 Read Online ACCESS Metric...
10.1073_pnas.2306564120
RESEARCH ARTICLE | IMMUNOLOGY AND INFLAMMATION OPEN ACCESS Contribution of the IGCR1 regulatory element and the 3′Igh CTCF- binding elements to regulation of Igh V(D)J recombination Zhuoyi Lianga,b,c,1,2, Lijuan Zhaoa,b,c,1, Adam Yongxin Yea,b,c,1, Sherry G. Lina,b,c,1, Yiwen Zhanga,b,c, Chunguang Guoa,b,c, Hai- Qia...
10.1073_pnas.2300052120
RESEARCH ARTICLE | NEUROSCIENCE OPEN ACCESS Glial dysregulation in the human brain in fragile X-associated tremor/ataxia syndrome Caroline M. Diasa,b,c,d,1, Biju Issace, Liang Sune, Abigail Lukowiczd, Maya Talukdarb,f Shira Rockowitzb,e, and Christopher A. Walshb,c,i,j,1 , Michael B. Millerb,h , Shyam K. Akulab,g ...
10.1016_j.cell.2023.06.002
A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t HHS Public Access Author manuscript Cell. Author manuscript; available in PMC 2023 July 27. Published in final edited form as: Cell. 2023 July 20; 186(15): 3148–3165.e20. doi:10.1016...
10.1016_j.cell.2023.03.031
A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t HHS Public Access Author manuscript Cell. Author manuscript; available in PMC 2023 July 05. Published in final edited form as: Cell. 2023 May 11; 186(10): 2127–2143.e22. doi:10.1016/...
10.1073_pnas.2221415120
RESEARCH ARTICLE NEUROSCIENCE Reward expectations direct learning and drive operant matching in Drosophila Adithya E. Rajagopalana,b ID , Ran Darshana,c, Karen L. Hibbarda, James E. Fitzgeralda, and Glenn C. Turnera,1 ID Edited by Leslie C. Griffith, Brandeis University, Waltham, MA; received January 3, 2023; accepte...
10.1073_pnas.2217096120
RESEARCH ARTICLE | BIOPHYSICS AND COMPUTATIONAL BIOLOGY OPEN ACCESS Structure of WNT inhibitor adenomatosis polyposis coli down-regulated 1 (APCDD1), a cell-surface lipid-binding protein Fu-Lien Hsieha,b,1, Tao-Hsin Changa,b,1,2 , and Jeremy Nathansa,b,f,g,2 , Sandra B. Gabellic,d,e,3 Contributed by Jeremy Nathan...
10.1016_j.isci.2022.105093
iScience ll OPEN ACCESS Article NOX-like ROS production by glutathione reductase Julia M. Diaz, Xinying Shi j2diaz@ucsd.edu Highlights Glutathione reductase expressed from a microbial phototroph is found to produce ROS This promiscuous reaction shows similar kinetics and inhibition as NOX-derived ROS The GR pat...
10.1016_j.aim.2022.108778
Burness, T., & Guralnick, R. (2022). Fixed point ratios for finite primitive groups and applications. Advances in Mathematics, 411(A), Article 108778. https://doi.org/10.1016/j.aim.2022.108778 Publisher's PDF, also known as Version of record License (if available): CC BY Link to published version (if available): 10....
10.1080_15476286.2023.2231280
RNA BIOLOGY 2023, VOL. 20, NO. 1, 444–456 https://doi.org/10.1080/15476286.2023.2231280 RESEARCH PAPER SARS-CoV-2 Nsp1 mediated mRNA degradation requires mRNA interaction with the ribosome Soraya I. Shehata a and Roy Parker b aDepartment of Molecular, Cellular, and Developmental Biology...
10.1021_acscentsci.2c01385
http://pubs.acs.org/journal/acscii Research Article Enzymatic Fluoromethylation Enabled by the S‑Adenosylmethionine Analog Te- Adenosyl‑L‑(fluoromethyl)homotellurocysteine Syam Sundar Neti, Bo Wang,* David F. Iwig, Elizabeth L. Onderko, and Squire J. Booker* Cite This: ACS Cent. Sci. 2023, 9, 905−914 Read Online A...
10.1016_j.celrep.2023.112408
A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t HHS Public Access Author manuscript Cell Rep. Author manuscript; available in PMC 2023 August 22. Published in final edited form as: Cell Rep. 2023 May 30; 42(5): 112408. doi:10.1016...
10.1016_j.cell.2023.07.039
Phage-assisted evolution and protein engineering yield compact, efficient prime editors Resource Graphical abstract Authors Jordan L. Doman, Smriti Pandey, Monica E. Neugebauer, ..., Jakub Tolar, Mark J. Osborn, David R. Liu Correspondence drliu@fas.harvard.edu In brief Phage-assisted continuous evolution and prote...
10.1016_j.str.2023.03.011
A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t HHS Public Access Author manuscript Structure. Author manuscript; available in PMC 2023 May 15. Published in final edited form as: Structure. 2023 May 04; 31(5): 518–528.e6. doi:10.1...
10.1073_pnas.2220528120
RESEARCH ARTICLE | BIOPHYSICS AND COMPUTATIONAL BIOLOGY OPEN ACCESS PRC2 direct transfer from G-quadruplex RNA to dsDNA has implications for RNA-binding chromatin modifiers Wayne O. Hemphilla,b , and Thomas R. Cecha,b,1 , Anne R. Goodinga,b , Regan Fenskea,b Edited by John Kuriyan, Vanderbilt University, Nashvil...
10.1073_pnas.2220159120
RESEARCH ARTICLE | CELL BIOLOGY OPEN ACCESS Osteolectin increases bone elongation and body length by promoting growth plate chondrocyte proliferation Jingzhu Zhanga , Liming Dua, Bethany Davisa, Zhimin Gua,1, Junhua Lyua, Zhiyu Zhaoa, Jian Xua , and Sean J. Morrisona,b,c,2 Contributed by Sean J. Morrison; receive...
10.1021_acschembio.3c00413
pubs.acs.org/acschemicalbiology This article is licensed under CC-BY 4.0 Articles Direct Modulators of K‑Ras−Membrane Interactions Johannes Morstein,* Rebika Shrestha, Que N. Van, César A. López, Neha Arora, Marco Tonelli, Hong Liang, De Chen, Yong Zhou, John F. Hancock, Andrew G. Stephen, Thomas J. Turbyville, and ...
10.1002_advs.202300445
RESEARCH ARTICLE www.advancedscience.com Cellular Composition and 5hmC Signature Predict the Treatment Response of AML Patients to Azacitidine Combined with Chemotherapy Guanghao Liang, Linchen Wang, Qiancheng You, Kirk Cahill, Chuanyuan Chen, Wei Zhang, Noreen Fulton, Wendy Stock, Olatoyosi Odenike,* Chuan He,* and...
10.1021_acscentsci.3c00547
http://pubs.acs.org/journal/acscii This article is licensed under CC-BY 4.0 Article Molecular Crowding Facilitates Ribozyme-Catalyzed RNA Assembly Saurja DasGupta,* Stephanie Zhang, and Jack W. Szostak* Cite This: ACS Cent. Sci. 2023, 9, 1670−1678 Read Online ACCESS Metrics & More Article Recommendations *sı S...
10.1016_j.cell.2023.05.028
A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t A u t h o r M a n u s c r i p t HHS Public Access Author manuscript Cell. Author manuscript; available in PMC 2023 August 18. Published in final edited form as: Cell. 2023 June 22; 186(13): 2765–2782.e28. doi:10.10...
10.1016_j.jbc.2023.105073
RESEARCH ARTICLE Mitochondrial double-stranded RNA triggers induction of the antiviral DNA deaminase APOBEC3A and nuclear DNA damage , Rémi Buisson4,5 Received for publication, May 8, 2023, and in revised form, June 27, 2023 Published, Papers in Press, July 19, 2023, https://doi.org/10.1016/j.jbc.2023.105073 Chloe W...
10.1016_j.isci.2021.102204
UC San Diego UC San Diego Previously Published Works Title Sensitivity of the mangrove-estuarine microbial community to aquaculture effluent Permalink https://escholarship.org/uc/item/3229890c Journal iScience, 24(3) ISSN 2589-0042 Authors Erazo, Natalia G Bowman, Jeff S Publication Date 2021-03-01 DOI 1...
10.1016_j.jbc.2023.105109
RESEARCH ARTICLE Structural insight into G-protein chaperone-mediated maturation of a bacterial adenosylcobalamin-dependent mutase , Daphne A. Faber2 Received for publication, May 23, 2023, and in revised form, July 20, 2023 Published, Papers in Press, July 28, 2023, https://doi.org/10.1016/j.jbc.2023.105109 Frances...
10.1016_j.xgen.2023.100356
Article Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions Graphical abstract Authors Eduardo A. Maury, Maxwell A. Sherman, Giulio Genovese, ..., Jonathan Sebat, Eunjung A. Lee, Christopher A. Walsh Correspondence christopher.walsh@childrens.harvar...
10.1021_acscentsci.3c00160
http://pubs.acs.org/journal/acscii Research Article Macrocyclization and Backbone Rearrangement During RiPP Biosynthesis by a SAM-Dependent Domain-of-Unknown-Function 692 Richard S. Ayikpoe, Lingyang Zhu, Jeff Y. Chen, Chi P. Ting, and Wilfred A. van der Donk* Cite This: ACS Cent. Sci. 2023, 9, 1008−1018 Read Onlin...
10.1021_acschembio.2c00840
pubs.acs.org/acschemicalbiology Articles Trapoxin A Analogue as a Selective Nanomolar Inhibitor of HDAC11 Thanh Tu Ho, Changmin Peng, Edward Seto, and Hening Lin* Cite This: ACS Chem. Biol. 2023, 18, 803−809 Read Online ACCESS Metrics & More Article Recommendations *sı Supporting Information ABSTRACT: Histone ...
10.1093_gbe_evad100
GBE No Transcriptional Compensation for Extreme Gene Dosage Imbalance in Fragmented Bacterial Endosymbionts of Cicadas Noah Spencer 1, Piotr Łukasik2,3, Mariah Meyer2,4, Claudio Veloso5, and John P. McCutcheon1,2,6,* 1Biodesign Center for Mechanisms of Evolution and School of Life Sciences, Arizona State University...