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metadata
language:
  - en
license: mit
pretty_name: Pharma Pharmacological vs Contextual Signal Separation v0.1
dataset_name: pharma-pharmacological-vs-contextual-signal-separation-v0.1
tags:
  - clarusc64
  - pharma
  - placebo
  - nocebo
  - clinical-trials
  - signal-separation
task_categories:
  - tabular-regression
  - tabular-classification
size_categories:
  - n<1K
configs:
  - config_name: default
    data_files:
      - split: train
        path: data/train.csv
      - split: test
        path: data/test.csv

What this dataset tests

Whether a system can separate pharmacological effect from contextual modulation
in placebo-controlled clinical trial settings.

It treats context as a learnable component of the outcome manifold.

Required outputs

  • pure_pharmacological_effect
  • contextual_amplification_factor
  • nocebo_risk_index
  • signal_separation_confidence
  • effect_stability_score

Use case

Second layer of the Placebo/Nocebo Response Disentanglement Matrix.

Improves efficacy estimation by preventing:

  • placebo lift being counted as drug effect
  • nocebo effects being misread as toxicity
  • unstable effects being over-trusted