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trial_id
string
site_id
string
week
int64
supply_on_time_pct
float64
shipment_delay_days
int64
dose_interruptions_per_patient
float64
missed_dose_rate
float64
exposure_gap_days
int64
pk_trough_drop_pct
int64
efficacy_change
float64
efficacy_loss_next_60d
int64
label_efficacy_loss_next_60d
int64
TRIAL_SUP01
S01
4
0.96
1
0.2
0.03
1
5
0.12
0
0
TRIAL_SUP01
S01
6
0.94
2
0.3
0.04
2
8
0.1
0
0
TRIAL_SUP01
S02
8
0.9
4
0.5
0.06
3
12
0.07
0
0
TRIAL_SUP01
S02
10
0.84
6
0.8
0.09
5
18
0.03
1
1
TRIAL_SUP01
S03
12
0.78
8
1
0.12
7
24
-0.02
1
1
TRIAL_SUP02
S01
5
0.97
1
0.2
0.02
1
4
0.13
0
0
TRIAL_SUP02
S02
7
0.93
2
0.3
0.04
2
7
0.1
0
0
TRIAL_SUP02
S03
9
0.86
5
0.7
0.08
4
16
0.04
1
1
TRIAL_SUP02
S03
11
0.8
7
0.9
0.11
6
22
-0.01
1
1
TRIAL_SUP02
S04
6
0.91
3
0.4
0.05
3
10
0.08
0
0

Clinical Quad Supply Chain Dose Interruptions Exposure Gaps Efficacy Loss v0.1

Each row is a site week snapshot.

Core quad

Supply chain reliability
Dose interruptions
Exposure gaps
Efficacy loss

Target

label_efficacy_loss_next_60d

Files

data/train.csv
data/tester.csv
scorer.py

Evaluation

Run model on data/tester.csv
Return predictions row aligned
Score with scorer.py

License

MIT

This dataset identifies a measurable coupling pattern associated with systemic instability. The sample demonstrates the geometry. Production-scale data determines operational exposure.

What Production Deployment Enables • 50K–1M row datasets calibrated to real operational patterns • Pair, triadic, and quad coupling analysis • Real-time coherence monitoring • Early warning before cascade events • Collapse surface and recovery window modeling • Integration and implementation support Small samples reveal structure. Scale reveals consequence.

Enterprise & Research Collaboration Clarus develops production-scale coherence monitoring infrastructure for critical systems across healthcare, finance, infrastructure, and regulatory domains. For dataset expansion, custom coherence scorers, or deployment architecture: team@clarusinvariant.com

Instability is detectable. Governance determines whether it propagates.

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