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trial_id
stringclasses
10 values
signal_detection_drift
stringclasses
3 values
ae_coding_variance
stringclasses
3 values
unblinding_risk
stringclasses
3 values
dsmb_decision_delay
stringclasses
2 values
label
stringclasses
3 values
T601
high
high
high
high
collapse_risk
T602
low
low
low
low
coherent
T603
high
low
high
low
tradeoff
T604
medium
high
low
high
tradeoff
T605
high
high
low
high
tradeoff
T606
low
high
high
high
tradeoff
T607
medium
low
high
high
tradeoff
T608
high
medium
medium
high
tradeoff
T609
low
medium
low
high
tradeoff
T610
medium
low
low
low
coherent

Clinical Quad: Signal Detection Drift × AE Coding Variance × Unblinding Risk × DSMB Decision Delay

This dataset targets safety governance collapse.

Signals weaken or shift.
AE coding diverges across sites.
Unblinding pressure rises.
The DSMB response slows.

The quad can turn a manageable safety issue into a governance failure.

Variables

  • signal_detection_drift (low | medium | high)
  • ae_coding_variance (low | medium | high)
  • unblinding_risk (low | medium | high)
  • dsmb_decision_delay (low | medium | high)

Labels

  • coherent
  • tradeoff
  • collapse_risk

Collapse rule

All four dimensions high.

Why it matters

You want models to spot when “we are monitoring safety” is no longer true in practice.

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