aaronwzl/GestaltMatcher-Arc-GMDB

GestaltMatcher-Arc (GMDB) — self-trained reproduction

ArcFace ResNet-50 face encoder, pre-trained on Glint360K (~360K identities, ~17M faces) and fine-tuned on GestaltMatcherDB (GMDB) v1.1.2 to embed the facial gestalt of rare genetic syndromes. Produces a 512-d embedding; diagnosis is nearest-prototype cosine retrieval.

This is the face-specialist component of the SyndroDX open-world rare-disease diagnosis framework.

Training

backbone	ArcFace ResNet-50 (Glint360K pre-trained)
fine-tune data	GMDB v1.1.2, original (non-enhanced) aligned faces
loss	ArcFace margin
image size	112 x 112
embedding dim	512
batch size	2048
epochs	50

Benchmark (GMDB official patient-level split, n=476)

metric	value
top-1	52.5%
top-5	66.8%
top-10	74.2%

Provenance, license & responsible use

• Derived from GestaltMatcher-Arc (CC-BY-NC 4.0) — non-commercial, attribution required.
• Fine-tuned on GMDB, an access-controlled database of patient facial images. These weights are derived from controlled patient data; do not redistribute publicly without confirming the GMDB data use agreement. Private / research use.
• Face-recognition model trained on patient faces — handle under appropriate privacy/ethics controls.

Cite GestaltMatcher / GestaltMatcher-Arc and GMDB when using this model.