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+paper_id,doi,title,authors,year,journal,source_db,category,is_fraud,fraud_confidence,fraud_types,retraction_date,retraction_reason,pubpeer_url,stat_audit_score,figure_forensics_score,methodology_score,citation_score,reproducibility_score,novelty_score,grim_score,sprite_score,granularity_score,pcurve_score,effect_size_score,retraction_score,cartel_score,llm_score,overall_risk_score,abstract_text,full_text_path,field_of_study,labeling_method,labeled_by,notes
+SPB-0001,10.1159/000546362,Fenbendazole as an Anticancer Agent? A Case Series of Self-Administration in Three Patients.,"Makis William, Baghli Ilyes, Martinez Pierrick",2025,Case reports in oncology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Fenbendazole (FBZ), an inexpensive and widely accessible antiparasitic drug used in veterinary medicine, has garnered growing interest for its potential as an anticancer therapy. Preclinical studies suggest that FBZ exerts its anticancer effects through a wide variety of mechanisms. While FBZ has shown promise both in vitro and in vivo studies, clinical evidence supporting its use and efficacy in treating metastatic cancer is currently limited. This report highlights 3 cases of patients with advanced cancer - including breast, prostate, and melanoma. Two patients achieved complete remission, and one achieved near-complete remission after incorporating FBZ into their treatment regimens alongside other therapies (excluding chemotherapy). All three patients tolerated FBZ without any reported adverse effects, and remission was sustained during follow-up periods ranging from 11 months to nearly 3 years. FBZ demonstrates potential as a novel promising therapeutic option for repurposing in on",,,auto_pubmed,scipeerai_collector_v1,pmid:40605964
+SPB-0002,10.1038/s41564-025-01985-x,Metabolic remodelling produces fumarate via the aspartate-argininosuccinate shunt in macrophages as an antiviral defence.,"Xia Wenjun, Mao Youxiang, Xia Ziyan, Cheng Jie, Jiang Peng",2025,Nature microbiology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Metabolic remodelling underpins macrophage effector functions in response to various stimuli, but the mechanisms involved are unclear. Here we report that viral-infection-induced inflammatory stimulation causes a rewiring of the urea cycle and the tricarboxylic acid cycle metabolism in macrophages to form a cyclic pathway called the aspartate-argininosuccinate (AAS) shunt. Using RNA sequencing, unbiased metabolomics and stable isotope tracing, we found that fumarate generated from the AAS shunt is driven by argininosuccinate synthase (ASS1) in the cytosol and potentiates inflammatory effects. Genetic ablation of ASS1 reduces intracellular fumarate levels and interferon-β production, and mitochondrial respiration is also suppressed. Notably, viral challenge or fumarate esters enhance interferon-β production via direct succination of the mitochondrial antiviral signalling protein and activation of the retinoic acid-inducible gene-I-like receptor signalling. In addition to the vesicular s",,,auto_pubmed,scipeerai_collector_v1,pmid:40251448
+SPB-0003,10.1016/j.jinf.2025.106530,Ivermectin and COVID-19.,"Butler Christopher C, Hobbs F D Richard, Little Paul, Richards Duncan, Saville Benjamin R, et al.",2025,The Journal of infection,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,,,,auto_pubmed,scipeerai_collector_v1,pmid:40494426
+SPB-0004,10.1002/jcsm.13779,Nestin Regulates Autophagy-Dependent Ferroptosis Mediated Skeletal Muscle Atrophy by Ubiquitinating MAP 1LC3B.,"Han Shunshun, Zhao Xiyu, Yu Chunlin, Cui Can, Zhang Yao, et al.",2025,"Journal of cachexia, sarcopenia and muscle",pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Programmed cell death plays a critical role in skeletal muscle atrophy. Ferroptosis, an iron-dependent form of programmed cell death driven by lipid peroxidation, has been implicated in various diseases, but its role in skeletal muscle atrophy remains unclear. Ferroptosis in skeletal muscle atrophy was investigated using two models: dexamethasone (Dex)-induced atrophy (n = 6 independent cell cultures per group) and simulated microgravity (n = 6 mice per group). Conditional Nestin knockout (KO) mice were generated using CRISPR/Cas9 (n = 6-8 mice per group), with wild-type (WT) controls (n = 6-8). Phenotypic analyses included histopathology (HE staining), functional assessments (muscle strength, weight analysis, treadmill), and dystrophy evaluation (dystrophin staining). Molecular analyses involved flow cytometry, ELISA, transmission electron microscopy, PI staining, and IP/MS to delineate Nestin-regulated ferroptosis pathways in skeletal muscle atrophy. Ferroptosis was significantly act",,,auto_pubmed,scipeerai_collector_v1,pmid:40183241
+SPB-0005,10.1186/s12943-025-02300-2,Circular RNA circDCUN1D4 suppresses hepatocellular carcinoma development via targeting the miR-590-5p/ TIMP3 axis.,"Li Hongyu, Su Bing, Jiang Yan, Zhang Boyang, Du Rulong, et al.",2025,Molecular cancer,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Hepatocellular carcinoma (HCC) is a major global health concern, necessitating innovative therapeutic strategies. In this study, we investigated the functional role of circular RNA circDCUN1D4 in HCC progression and its potential therapeutic implications. It was found that HCC patients exhibiting higher levels of circDCUN1D4 demonstrated a more favorable survival rate. Furthermore, we revealed that circDCUN1D4 suppressed HCC cell proliferation, migration, and invasion. Mechanistically, circDCUN1D4 was identified as a sponge for miR-590-5p, leading to the downregulation of its downstream target, Tissue Inhibitor of Metalloproteinase 3 (TIMP3). Importantly, circDCUN1D4 administration through In vivo jet-PEI exhibited a robust inhibitory effect on tumor progression without causing notable toxicity in mice. Overall, our findings highlight circDCUN1D4 as a promising therapeutic candidate for HCC, unraveling its intricate regulatory role through the miR-590-5p/TIMP3 axis. This study contribu",,,auto_pubmed,scipeerai_collector_v1,pmid:40128740
+SPB-0006,10.1186/s13018-024-05429-w,A meta-analysis and systematic review of the clinical efficacy and safety of platelet-rich plasma combined with hyaluronic acid (PRP + HA) versus PRP monotherapy for knee osteoarthritis (KOA).,"Du Dan, Liang Yuan",2025,Journal of orthopaedic surgery and research,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"KOA, a chronic degenerative joint disease, is commonly treated with intra-articular HA and PRP, used alone or in combination. However, the efficacy and safety of combination therapy (PRP + HA) remain unclear. The aim of this systematic review and meta-analysis is to assess the clinical effectiveness and safety profile of PRP + HA versus PRP monotherapy for KOA. A systematic search was conducted using four electronic databases (PubMed, EMBASE, Scopus, and Cochrane Library) to select publications published in peer-reviewed journals. The mean difference (MD) and risk ratio (RR) was calculated, along with their 95% confidence intervals. We assessed heterogeneity using Cochrane Q and I<sup>2</sup>statistics and the appropriate p-value. The analysis used RevMan 5.4. GRADE system was used for evidence assessment for each outcome parameter. This meta-analysis of 11 RCTs (n = 1023 KOA patients) revealed that PRP + HA has substantial effectiveness than PRP alone in reducing OMAC total scores [MD",,,auto_pubmed,scipeerai_collector_v1,pmid:39819683
+SPB-0007,10.1016/j.idcr.2025.e02278,"Post spike syndrome (PSS): Simple solution leading to resolving results, five cases report.","Zeballos Roberto S, da Silva Helbingen Mariely Fernanda, Melo Paulo Macio Porto, Alves Francisco Eduardo Cardoso, Salvino Caio Roberto, et al.",2025,IDCases,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Post-Spike Syndrome (PSS) is an emerging condition associated with the Spike protein, originating from both SARS-CoV-2 infection and mRNA-based therapies. This case series explores the significant clinical impact of PSS, characterized By gut dysbiosis, systemic inflammation, and immune activation, leading to multisystem manifestations such as fatigue, brain fog, neuropathies, and reactivation of pre-existing diseases. A simple therapeutic approach was applied to five patients, resulting in notable symptom improvement. This case series includes five patients diagnosed with interstitial granulomatous dermatitis, polymyalgia rheumatica, peripheral polyneuropathy, drug-refractory epilepsy, and trigeminal neuralgia. A common pathophysiological mechanism-vasculitis triggered by both SARS-CoV-2 and mRNA-based therapies-was hypothesised. The patients exhibited a satisfactory response to the proposed therapeutic strategy. This is an observational and descriptive study, with data collected retro",,,auto_pubmed,scipeerai_collector_v1,pmid:40671933
+SPB-0008,10.1136/bmj-2024-083382,Prevention of acute myocardial infarction induced heart failure by intracoronary infusion of mesenchymal stem cells: phase 3 randomised clinical trial (PREVENT-TAHA8).,"Attar Armin, Mirhosseini Seyed Alireza, Mathur Anthony, Dowlut Sheik, Monabati Ahmad, et al.",2025,BMJ (Clinical research ed.),pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"To assess the effect of intracoronary infusion of mesenchymal stem cells on the development of post-myocardial infarction heart failure. Phase 3 randomised clinical trial. Three tertiary hospitals in Shiraz, Iran. 420 patients with a first ST segment elevation acute myocardial infarction and left ventricular ejection fraction <40% were enrolled and randomised in a 1:2 ratio to receive intervention or standard care. Intracoronary infusion of allogenic Wharton's jelly derived mesenchymal stem cells within 3-7 days of acute myocardial infarction in addition to standard care. The primary endpoint was incidence of heart failure. Secondary endpoints included readmission to hospital for heart failure, all cause mortality, cardiovascular mortality, and readmission to hospital for myocardial infarction. Changes in left ventricular ejection fraction within six months post-myocardial infarction were compared between groups. A total of 396 patients (136 in the intervention group and 260 in the con",,,auto_pubmed,scipeerai_collector_v1,pmid:41224473
+SPB-0009,10.1093/jbmr/zjaf010,"RETRACTED: Comparative cardiovascular safety of romosozumab versus bisphosphonates in Japanese patients with osteoporosis: a new-user, active comparator design with instrumental variable analyses.","Tominaga Ryoji, Ikenoue Tatsuyoshi, Ishii Ryosuke, Niihata Kakuya, Aita Tetsuro, et al.",2026,Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,,,,auto_pubmed,scipeerai_collector_v1,pmid:39823291
+SPB-0010,10.1080/01635581.2025.2497095,Ketogenic Diets Are Associated with an Elevated Risk for All Cancers: Insights from a Cross-Sectional Analysis of the NHANES 2001-2018.,"Liu Yuping, Qu Xiaolong, Liu Dingsheng, Yang Dongming",2025,Nutrition and cancer,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Ketogenic diet (KD) has increasingly been applied in anti-cancer therapy in recent years; however, its effect on cancer development risk remains controversial. We examined the association between dietary ketogenic ratio (DKR) and cancer incidence using cross-sectional data from the National Health and Nutrition Examination Survey (NHANES) conducted between 2001 and 2018. Dietary intake information was collected via a detailed 24-h dietary recall survey, and DKR values were calculated using a specialized formula. Multivariate logistic regression analysis was performed to evaluate the correlation between DKR and tumor occurrence, with restricted cubic splines (RCS) utilized to assess potential nonlinear relationships. Furthermore, a two-stage linear regression analysis was carried out to determine the inflection point. Furthermore, subgroup analyses were conducted stratified by demographic variables, including age, gender, race, body mass index (BMI), smoking status, and diabetes mellitu",,,auto_pubmed,scipeerai_collector_v1,pmid:40641124
+SPB-0011,10.1038/s41388-025-03410-3,Non-classic deubiquitinase USP13 inhibits bladder cancer metastasis through destabilizing cytoplasmic KDM3A.,"Hu Hongji, Zhan Xiangpeng, Xiong Yunqiang, Yuan Ruize, Du Yuanzhuo, et al.",2025,Oncogene,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Bladder cancer (BLCa) metastasis is a predominant cause of death for bladder cancer patients. Histone demethylase KDM3A specifically removes the repressive mono- or di-methyl marks from H3K9 and thus contributes to the activation of gene transcription. However, the underlying mechanisms of KDM3A in bladder cancer are poorly understood. Here, we report that high levels of KDM3A are associated with bladder cancer clinical progression. KDM3A silencing inhibits bladder cancer cell growth, cell migration and invasion in vitro and in vivo. Mechanistically, we identify that non-classic deubiquitinase USP13 interacts with KDM3A to promote its degradation in cytoplasm via the proteasome-specific pathway. USP13 was significantly down-regulated in bladder cancer tissues and negatively associated with KDM3A expression. Furthermore, we show in bladder injected-liver metastasis xenograft model that USP13 inhibits bladder cancer metastasis through destabilizing cytoplasmic KDM3A. Collectively, our fi",,,auto_pubmed,scipeerai_collector_v1,pmid:40253486
+SPB-0012,10.3389/fimmu.2024.1410904,Fexuprazan safeguards the esophagus from hydrochloric acid-induced damage by suppressing NLRP1/Caspase-1/GSDMD pyroptotic pathway.,"Kim Seo Yeon, Yoon Jung-Ho, Jung Da Hyun, Kim Ga Hee, Kim Chul Hoon, et al.",2024,Frontiers in immunology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Proton pump inhibitors (PPIs) and potassium-competitive acid blockers (P-CABs) are widely used to manage gastric acid-related disorders by inhibiting hydrochloric acid (HCl) secretion from parietal cells in the stomach. Although PPIs are known to have anti-inflammatory properties beyond their role in inhibiting gastric acid secretion, research on P-CABs is lacking. In this study, we aimed to investigate whether all available P-CABs exhibit anti-inflammatory effects in gastroesophageal reflux-induced esophagitis and to elucidate the underlying mechanisms. Het-1A cells, normal esophageal epithelial cells, were treated with HCl (pH 4) for 30 min. Esomeprazole, a representative PPI, and three currently marketed P-CABs (vonoprazan, tegoprazan, and fexuprazan) were used for pretreatment. Total RNA sequencing was performed using Het-1A cells pretreated with 1% DMSO or fexuprazan, followed by exposure to HCl. Pyroptosis was measured using lactate dehydrogenase (LDH) release and Annexin V-FITC/",,,auto_pubmed,scipeerai_collector_v1,pmid:39737189
+SPB-0013,10.1016/j.amjmed.2025.03.011,WITHDRAWN: Pharmacogenomics: Implementation of Precision Medicine.,"Alpert Joseph S, Chen Qin M, Mulyar Oleh Alex, Acharya Deepak, Hung Olivia, et al.",2025,The American journal of medicine,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,,,,auto_pubmed,scipeerai_collector_v1,pmid:40090392
+SPB-0014,10.1002/advs.202503897,Histone Lactylation-Driven Upregulation of VRK1 Expression Promotes Stemness and Proliferation of Glioma Stem Cells.,"Li Jinna, Tang Chenyue, Zhang Xuefeng, Xing Rui, Guo Qing",2025,"Advanced science (Weinheim, Baden-Wurttemberg, Germany)",pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Glioblastoma (GBM) is the most malignant primary brain tumor in adults, with glioma stem cells (GSCs) as a subpopulation contributing to treatment resistance and recurrence. This study investigates the role of lactate and its regulatory gene, vaccinia-related kinase 1 (VRK1), in the regulation of GSC stemness. Utilizing multiple glioma-related databases and patient-derived GSCs, it is discovered that lactate enhances the stemness and proliferation of GSCs via VRK1. Mechanistically, lactate promotes histone lactylation (H3K18la) at the VRK1 promoter in GSCs, thereby upregulating VRK1 expression. VRK1 enhances Y-box binding protein 1 (YBX1) protein stability by inhibiting its ubiquitination and degradation, and phosphorylates YBX1 to promote its nuclear translocation, thereby regulating GSC stemness and proliferation via the YBX1/SOX2 pathway. Additionally, the VRK1-targeted nanoliposome A/TMZ-siVRK1 effectively suppresses the stemness and proliferation of GSCs, demonstrating its therape",,,auto_pubmed,scipeerai_collector_v1,pmid:40990975
+SPB-0015,10.1016/j.redox.2025.103806,Extracellular vesicle-mediated delivery of mitochondrial circRNA MTCO2 protects against cerebral ischemia by modulating mPTP-dependent ferroptosis.,"Yang Jialei, Wu Shipo, He Miao",2025,Redox biology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Ischemic stroke remains a major cause of mortality and long-term disability, with few effective neuroprotective treatments currently available. Ferroptosis, an iron-dependent form of regulated cell death marked by lipid peroxidation, is increasingly recognized as a driver of neuronal damage. However, the mitochondrial mechanisms linking ischemia to ferroptosis remain poorly defined. Here, we identify circMTCO2, a mitochondria-encoded circular RNA, as a novel endogenous modulator of neuronal ferroptosis. CircMTCO2 expression is dynamically downregulated following cerebral ischemia/reperfusion both in vitro and in vivo. Mechanistically, circMTCO2 binds directly to adenine nucleotide translocase 1 (ANT1), a key component of the mitochondrial permeability transition pore (mPTP), thereby inhibiting mPTP opening and suppressing mitochondrial ROS (mtROS) release. Disruption of the binding site abolishes the circMTCO2-ANT1 interaction and eliminates the protective effects of circMTCO2. To rest",,,auto_pubmed,scipeerai_collector_v1,pmid:40768899
+SPB-0016,10.1016/j.lfs.2025.123819,Dapagliflozin attenuates diabetic cardiomyopathy via NRF2 protein upregulation-driven glutathione synthesis to inhibit myocardial ferroptosis.,"Chen Xuepin, Wang Tianying, Gao Yan, Wang Guoan, Zhuang Likun, et al.",2025,Life sciences,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Ferroptosis has emerged as a critical pathological mechanism contributing to the development and progression of type 2 diabetic cardiomyopathy (DCM). Dapagliflozin (DAPA), a sodium-glucose co-transporter 2 inhibitor (SGLT2i) with established cardiovascular benefits, however, DAPA's efficacy in modulating ferroptosis during type 2 DCM remains to be elucidated. In vivo, using a spontaneously diabetic Goto-Kakizaki (GK) rat model, we conducted proteomic profiling revealing distinct myocardial ferroptosis signatures associated with dysregulated glutathione metabolism across normal control, GK and GK + DAPA groups. Subsequent validation demonstrated characteristic ferroptosis markers in diabetic myocardium, including elevated Fe<sup>2+</sup> level, increased Fe<sup>3+</sup> deposition, heightened malondialdehyde (MDA)-mediated lipid peroxidation, and ultrastructural mitochondrial aberrations. DAPA administration (5 mg/kg/d) significantly restored glutathione homeostasis, mitigated myocardia",,,auto_pubmed,scipeerai_collector_v1,pmid:40550388
+SPB-0017,10.1053/j.semnuclmed.2025.06.005,Radiotracing the Future: Non-FDG Radiotracers Nuclear Medicine.,"Fuso Giuseppe Arturo, Bianciardi Gianfilippo, Mei Riccardo, Brusa Irene, Emiliani Stefano, et al.",2025,Seminars in nuclear medicine,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Positron Emission Tomography/Computed Tomography (PET/CT) is an advanced hybrid imaging modality that synergistically combines metabolic and anatomical data, revolutionizing diagnostic accuracy and therapeutic monitoring in various pathologies. While 18F-fluorodeoxyglucose (FDG) remains the cornerstone radiotracer for many oncologic and nononcologic applications, its limitations-such as nonspecific uptake in inflammation and limited sensitivity in certain tumor subtypes-have catalyzed the development and clinical adoption of non-FDG radiotracers. These novel agents exhibit diverse biological targets, enabling more precise characterization of tissue physiology and pathology. Among them, radiotracers such as 68Ga-DOTA Peptides, 18F-fluciclovine, 68Ga-PSMA, 11C-choline, and 18F-FDOPA have demonstrated utility in neuroendocrine tumors, prostate cancer, gliomas, and parkinsonian syndromes. Their application enhances disease detection, improves staging and restaging accuracy, and supports th",,,auto_pubmed,scipeerai_collector_v1,pmid:40675900
+SPB-0018,10.1016/j.jcpo.2025.100615,Evidence on vaping e-cigarettes as a risk factor for cancer: A systematic review.,"de Oliveira Guilherme Guedes, Magalhães Liberato Rebeca Milka Lemos, de Souza Amaxsell Thiago Barros, Sarmento Ayane Cristine Alves, de Moura Santos Edilmar, et al.",2025,Journal of cancer policy,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"This review aims to evaluate the association between e-cigarette use and cancer risk. A systematic review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Studies were sourced from PubMed/MEDLINE, LILACS, Embase, Web of Science, and Scopus up to September 2024. Observational studies evaluating the association between e-cigarette use and cancer risk were included. Data selection and extraction were performed independently and in pairs. The risk of bias was assessed using the Newcastle-Ottawa Scale (NOS) for cohort and case-control studies and the Joanna Briggs Institute (JBI) critical appraisal tool for cross-sectional studies. Ten studies were included in the final analysis, a total of 143,975 patients. Skin cancer represented 7 % (n = 635) of cases, followed by breast cancer at 4 % (n = 370), prostate cancer at 2 % (n = 234), melanoma at 1.4 % (n = 118), and colon cancer 1.2 % (n = 106). A single study identified associ",,,auto_pubmed,scipeerai_collector_v1,pmid:40691942
+SPB-0019,10.1177/13860291241291331,Value of blood perfusion index in guiding fluid resuscitation against septic shock.,"Lin Leqing, Liang Dongcheng, Yuan Wanrou, Mao Fengkai, Wang Baiyong, et al.",2025,Clinical hemorheology and microcirculation,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"ObjectiveSeptic shock is a serious medical condition characterized by extreme inflammation and blood vessel permeability. Fluid resuscitation is a crucial treatment for septic shock, but the optimal approach for fluid management remains controversial. In this study, we explored how blood perfusion index (PI) monitoring can help direct fluid resuscitation therapy for septic shock.MethodsBetween January 2019 and December 2021, 50 patients with septic shock were admitted to The Affiliated Hospital of Hangzhou Normal University and randomly assigned to either a control or study group (25 cases each). All patients were given the sepsis treatment bundle recommended by the 2018 guidelines and were subjected to Pulse Indicator Continuous Cardiac Output (PiCCO) -based hemodynamic monitoring. Fluid resuscitation was administered based on specific indicators in the control group. We used PI to direct fluid resuscitation in the research group. Several parameters were assessed, including blood lact",,,auto_pubmed,scipeerai_collector_v1,pmid:40434088
+SPB-0020,10.1007/s00280-025-04749-w,New recommendations for reversal of high-dose methotrexate cytotoxicity with folinic acid.,"Heldrup Jesper, Bleyer Archie, Ramsey Laura, Schaff Lauren, Bernhardt Brooke, et al.",2025,Cancer chemotherapy and pharmacology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Folinic acid (FA) rescue protocols to counter the adverse effects of high-dose methotrexate (HDMTX) vary widely, and the risk of over-rescue and potential adverse effects of excessive FA (e.g., hypercalcemia) are under-recognized issues when providing augmented rescue in cases of delayed methotrexate elimination (DME). This opinion summary defines over-rescue, describes its potential adverse impacts, highlights the risk of hypercalcemia associated with excessive FA dosing in patients with acute kidney injury (AKI) from HDMTX, and provides recommendations to improve safety and efficacy of FA rescue in patients receiving HDMTX. A multidisciplinary panel of experts with clinical experience in HDMTX treatment convened in three roundtable meetings to coalesce expert opinion and best published evidence on the pharmacology and clinical effects and interactions of FA and HDMTX. The type of FA (calcium folinate, calcium levofolinate, sodium levofolinate), dose, and frequency of FA administratio",,,auto_pubmed,scipeerai_collector_v1,pmid:40075030
+SPB-0021,10.3389/fimmu.2025.1630015,Regulated programmed cell death in acute lung injury: from pathogenesis to therapy.,"Liu Shi-Wen, Chen Yi-Jian, Liu Yi, Zhou Wen, Liu Xuan",2025,Frontiers in immunology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Acute lung injury (ALI) is a common, life-threatening lung disease with a high mortality rate, primarily associated with acute and severe inflammation of the lungs. There are many factors that lead to ALI, and abnormally advanced regulated programmed cell death (RCD) is considered to be an important process in the pathological process of ALI. Various forms of RCD have been discovered in recent years, including apoptosis, necroptosis, autophagy, ferroptosis and pyroptosis. Unlike necrosis, RCD is an active cell death mediated by a series of gene expression events that is essential for eliminating unnecessary and damaged cells as well as defense mechanisms. Previous studies have shown that RCD has a strong relationship with ALI. Therefore, it is important to describe the role of RCD not only to enhance our understanding of the pathophysiological processes of ALI, but also to improve the functional recovery after ALI. This review reviews the roles and mechanisms of various RCD (apoptosis,",,,auto_pubmed,scipeerai_collector_v1,pmid:40771815
+SPB-0022,10.1136/gutjnl-2025-334909,Unleashing the potential of exosome ncRNAs for early gastric cancer detection-a critical appraisal of machine learning approaches.,Zeng Xuefan,2025,Gut,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,,,,auto_pubmed,scipeerai_collector_v1,pmid:39988361
+SPB-0023,10.2196/77014,Effects of Tai Chi on Cognitive Function in Older Adults With Type 2 Diabetes Mellitus: Randomized Controlled Trial Using Wearable Devices in a Mobile Health Model.,"Chen Xi-Shuang, Liu Hui-Zhen, Fang Jingxian, Wang Sui-Jun, Han Yue-Xia, et al.",2025,Journal of medical Internet research,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Telemedicine is an effective and promising strategy, especially for the initial stages of a home-based therapeutic exercise program. The objectives of this study were 2-fold: first, to assess whether Tai Chi practice combined with wearable device-based monitoring improves cognitive function in this population, and second, to explore the underlying mechanisms for any improvements observed, including changes in physical activity levels and sleep patterns. The study was a randomized controlled trial in which participants were randomized (1:1:1) to receive usual care, fitness walking, or Tai Chi exercise. All indicators were assessed at baseline and 12-week follow-up. The usual care includes traditional diabetes education. Participants in the fitness walking group performed walking exercises on a treadmill under the supervision of a researcher 3 times a week for 12 weeks. Participants in the Tai Chi group practiced 24-style Simplified Tai Chi through live video streaming under the guidance",,,auto_pubmed,scipeerai_collector_v1,pmid:40957073
+SPB-0024,10.1016/j.amjcard.2025.01.020,Impella versus Non-Impella for Nonemergent High-Risk Percutaneous Coronary Intervention.,"Reddy Pavan, Merdler Ilan, Zhang Cheng, Cellamare Matteo, Ben-Dor Itsik, et al.",2025,The American journal of cardiology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"The benefit of mechanical circulatory support (MCS) with Impella (Abiomed, Inc, Danvers, MA) for patients undergoing nonemergent, high-risk percutaneous coronary intervention (HR-PCI) is unclear and currently the subject of a large randomized clinical trial (RCT), PROTECT IV. While contemporary registry data from PROTECT III demonstrated improvement of outcomes with Impella when compared with historical data (PROTECT II), there is lack of direct comparison to the HR-PCI cohort that did not receive Impella support. We retrospectively identified patients from our institution meeting PROTECT III inclusion criteria (left ventricular ejection fraction [LVEF] <35% with unprotected left main or last remaining vessel or LVEF <30% undergoing multivessel PCI), and compared this group (NonIMP) to the published outcomes data from the PROTECT III registry (IMP). Baseline differences were balanced using inverse propensity weighting (IPW). The co-primary outcome was major adverse cardiac events (MACE",,,auto_pubmed,scipeerai_collector_v1,pmid:39863240
+SPB-0025,10.1016/j.neuroimage.2025.121097,Test-retest reliability of coupling between cerebrospinal fluid flow and global brain activity after normal sleep and sleep deprivation.,"Zhao Weiwei, Rao Joy, Wang Ruosi, Chai Ya, Mao Tianxin, et al.",2025,NeuroImage,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"The glymphatic system (GS) plays a key role in maintaining brain homeostasis by clearing metabolic waste during sleep, with the coupling between global blood-oxygen-level-dependent (gBOLD) and cerebrospinal fluid (CSF) signals serving as a potential marker for glymphatic clearance function. However, the test-retest reliability and spatial heterogeneity of gBOLD-CSF coupling after different sleep conditions remain unclear. In this study, we assessed the test-retest reliability of gBOLD-CSF coupling following either normal sleep or total sleep deprivation (TSD) in 64 healthy adults under controlled laboratory conditions. The reliability was high after normal sleep (ICC = 0.763) but decreased following TSD (ICC = 0.581). Moreover, spatial heterogeneity was evident in participants with normal sleep, with lower-order networks (visual, somatomotor, and attention) showing higher ICC values compared to higher-order networks (default-mode, limbic, and frontoparietal). This spatial variation was",,,auto_pubmed,scipeerai_collector_v1,pmid:39986550
+SPB-0026,10.1038/s41564-025-01991-z,MAVS is a sensor of fumarate during antiviral immunity.,"Min Yukun, O'Neill Luke A J",2025,Nature microbiology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,,,,auto_pubmed,scipeerai_collector_v1,pmid:40269181
+SPB-0027,10.1016/j.clindermatol.2025.05.011,WITHDRAWN: Cancer and Hidradenitis Suppurativa.,"Cohen Philip R, Cohen-Kurzrock Rena A, Riahi Ryan R",2025,Clinics in dermatology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"The Publisher regrets that this article is an accidental duplication of an article that has already been published, http://dx.doi.org/10.1016/j.clindermatol.2025.05.011. The duplicate article has therefore been withdrawn. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/policies-and-standards/article-withdrawal.",,,auto_pubmed,scipeerai_collector_v1,pmid:40373946
+SPB-0028,10.1016/j.ijgc.2025.101828,Cervical cancer elimination in low-resource countries: low-cost strategy.,"Hemida Reda, Barakat Rafik, Nabil Hanan, Hasan Mohammed, Helal Adel, et al.",2025,International journal of gynecological cancer : official journal of the International Gynecological Cancer Society,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,,,,auto_pubmed,scipeerai_collector_v1,pmid:40300978
+SPB-0029,10.1016/j.ijbiomac.2025.145351,WITHDRAWN: ARHGAP4/ MYH9/ β-catenin/ c-Jun positive feedback loop regulates colorectal cancer stemness.,"Liu Shaolin, Chen Yizhen, Tan Song, Chen Yifan, Yang Changshun, et al.",2025,International journal of biological macromolecules,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,This article has been withdrawn at the request of the author(s) and/or editor due to an error in the publishing process. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/policies-and-standards/article-withdrawal.,,,auto_pubmed,scipeerai_collector_v1,pmid:40553870
+SPB-0030,10.1038/s41541-025-01145-6,Comparing Moderna's mRNA-1083 and Pfizer's dual-target mRNA vaccines for influenza and COVID-19.,"Akingbola Adewunmi, Adegbesan Abiodun, Adegoke Kolade, Idahor Courage, Mariaria Petra, et al.",2025,NPJ vaccines,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"This review examines Moderna's mRNA-1083 and Pfizer/BioNTech's mRNA-1020/1030 dual-target vaccines for COVID-19 and influenza. Both utilize mRNA technology, demonstrating strong immunogenicity and favorable safety profiles. Moderna's mRNA-1083 showed superior immune responses, while Pfizer's mRNA-1020/1030 performed well but was slightly less effective against influenza B. These vaccines simplify immunization strategies, enhance protection, and emphasize the need for global vaccine equity to prevent future outbreaks.",,,auto_pubmed,scipeerai_collector_v1,pmid:40413212
+SPB-0031,10.1016/j.bcp.2025.116949,Withdrawal notice to: ATR-mediated phosphorylation of RIPK1 inhibits DNA damage-induced necroptosis.,"Shi Shen-Nan, Xu Qiuyang, Jiao Xiaofei, Wen Yuanjia, Wu Yijie, et al.",2025,Biochemical pharmacology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,This article has been withdrawn at the request of the editor and publisher. The publisher regrets that an error occurred which led to the premature publication of this paper. This error bears no reflection on the article or its authors. The publisher apologizes to the authors and the readers for this unfortunate error. The full Elsevier Policy on Article Withdrawal can be found at (https://www.elsevier.com/about/policies-and-standards/article-withdrawal).,,,auto_pubmed,scipeerai_collector_v1,pmid:40228635
+SPB-0032,10.1016/j.jhep.2025.02.043,WITHDRAWN: Letter to the editor: Several questions about the study of hypothermic oxygenated machine perfusion.,"Yang Hanwen, Lei Simeng, Ji Zhili",2025,Journal of hepatology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,This article has been withdrawn at the request of the author(s) and/or editor due to an error in the publishing process. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/policies-and-standards/article-withdrawal,,,auto_pubmed,scipeerai_collector_v1,pmid:40056935
+SPB-0033,10.1126/science.adw9456,RETRACTED: Integrative phylogenomics positions sponges at the root of the animal tree.,"Steenwyk Jacob L, King Nicole",2025,"Science (New York, N.Y.)",pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Determining whether sponges or ctenophores root the animal tree has important implications for understanding early animal evolution. Here, we examined support for these competing hypotheses by constructing large and highly informative data matrices containing sequences from sponges, ctenophores, cnidarians, bilaterians, and diverse animal relatives. The new data matrices and 10 published datasets were analyzed in 785 topology tests conducted using integrative phylogenomics, a method that unifies concatenation and coalescence to identify genes with a consistent phylogenetic signal. All 490 statistically significant tests supported the sponge-sister hypothesis and none supported the ctenophore-sister hypothesis; the remaining 295 tests were inconclusive. These results provide compelling evidence for the sponge-sister hypothesis and suggest that integrative phylogenomics provides a robust and powerful approach for disentangling branches in the tree of life.",,,auto_pubmed,scipeerai_collector_v1,pmid:41232001
+SPB-0034,10.1186/s12348-025-00467-9,Efficacy and safety of water-free topical cyclosporine for moderate to severe dry eye disease: a systematic review and meta-analysis.,"Rehan Ahmed Hamed, El-Masry Hassan, Abdultawab Roaa, Ahmed Manahil, Kasem Rawan Ashraf, et al.",2025,Journal of ophthalmic inflammation and infection,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Dry eye disease (DED) is a widely prevalent ocular symptom, with an estimated global prevalence of around 12%. The increasing prevalence of this disease among adults poses a significant morbidity burden. The aim of this study is to analyze the efficacy and safety of water-free cyclosporine, a new intervention suggested to be more effective in treating DED. A comprehensive literature search was conducted using databases as PubMed, Cochrane, Scopus and Web of Science. Keywords used include ""dry eye"", ""water-free cyclosporine"", and ""DED"" among others. Randomized controlled trials (RCTs) evaluating the use of water-free cyclosporine in patients with dry eye disease were included. A total of 4 RCTs were included in our analysis, consisting of 1,471 participants. Primarily, efficacy outcomes were evaluated such as total and central corneal fluorescence staining score (tCFS and cCFS) and dryness score. Our secondary outcomes evaluated the safety of these drugs by considering the treatment-eme",,,auto_pubmed,scipeerai_collector_v1,pmid:40048020
+SPB-0035,10.1111/xen.70023,An IgM Cleaving Enzyme for Clearance of Anti-Pig Xenoreactive Antibodies in a Nonhuman Primate Model.,"Martinino Alessandro, Smith Timothy J, Elmore Zachary C, Yoon Janghoon, Ladowski Joseph, et al.",2025,Xenotransplantation,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"The removal of preformed antibodies with cleaving enzymes like IdeS (imlifidase) has demonstrated therapeutic potential in organ transplantation for sensitized recipients. However, preformed xenoreactive antibodies (XAbs) against porcine glycans are predominantly IgM and considered detrimental in pig-to-human xenotransplantation. Recombinant IceM, an endopeptidase cleaving IgM, was generated in Escherichia coli (E. coli). Four maximally MHC-mismatched rhesus macaques underwent two serial skin transplantations to model allosensitized patients awaiting xenotransplantation. IceM was administered IV in allosensitized animals at 28 and 56 days after the first skin transplantation to assess in vivo IgM cleavage. Total IgG and IgM were quantified with western blot, and anti-pig (xenoreactive) IgG/IgM were evaluated using flow crossmatch. B cells and their subpopulations were assessed using flow cytometry. IceM selectively cleaved human IgM, while showing no cleavage activity toward other isot",,,auto_pubmed,scipeerai_collector_v1,pmid:39960355
+SPB-0036,10.1093/eurjpc/zwaf070,Effects of inpatient and outpatient cardiac rehabilitation on the 5-year prognosis in patients with acute myocardial infarction.,"Suematsu Yasunori, Minei Akira, Sumita Yoko, Kanaoka Koshiro, Nakai Michikazu, et al.",2025,European journal of preventive cardiology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Cardiac rehabilitation (CR) has been shown to improve the prognosis of patients with acute myocardial infarction (AMI). In Japan, the duration of hospitalization has shortened, resulting in a lower participation rate in CR among outpatients. Therefore, we evaluated the effects of CR, stratified into inpatient and outpatient phases, on the prognosis of patients with AMI in Japan. A multi-centre, retrospective, cohort study in which extracted 4411 AMI patients from 72 institutes throughout Japan who were identified from a Japanese Registry Of All cardiac and vascular Diseases (JROAD) in 2014 was performed. The JROAD is a database from Diagnosis Procedure Combination, and we additionally investigated the detailed information about severity, complications, treatment of AMI, the results of examinations, and the 5-year prognosis with respect to CR (JROAD-CR). The patients were divided into four groups, depending on their history of CR as inpatients and outpatients. The percentages of inpatie",,,auto_pubmed,scipeerai_collector_v1,pmid:40117194
+SPB-0037,10.1002/anie.202502068,Spider Eye Development Editing and Silk Fiber Engineering Using CRISPR-Cas.,"Santiago-Rivera Edgardo, Scheibel Thomas",2025,Angewandte Chemie (International ed. in English),pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"CRISPR-Cas9 gene editing represents an effective and precise technology to induce mutations in the genome, and it has been applied to a wide range of organisms for diverse purposes. However, CRISPR-based gene editing in spiders has not been reported to date. In this study, we demonstrate CRISPR-mediated microinjection in parental spiders leading to both knock-out (KO) and knock-in (KI) mutations within the spider's offspring. The KO of the gene sine oculis causes total eye loss, confirming the role of the gene in the development of all spider eyes. The KI of a monomeric red fluorescent protein (mRFP-KI) within a spider silk gene encoding one compound of the major ampullate silk of the spider Parasteatoda tepidariorum yields red fluorescent silk fibers. This finding demonstrates the feasibility of functionalizing silk proteins in spiders using CRISPR-based gene editing without influencing silk assembly. Our study expands the application of CRISPR to spiders and provides insights in the ",,,auto_pubmed,scipeerai_collector_v1,pmid:40223236
+SPB-0038,10.7759/cureus.78138,Impact of Dual Antiplatelet Therapy Versus Monotherapy in Acute Stroke Management: A Systematic Review.,"Adil Areeb Muhammad, Mohanty Rakesh, Hisoriya Hiren B, Mithani Javeria, Ogungbemi Oluwatobiloba T, et al.",2025,Cureus,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"This systematic review evaluates the comparative efficacy and safety of dual antiplatelet therapy (DAPT) versus monotherapy in the management of acute ischemic stroke and transient ischemic attack (TIA). Six studies, published between 2019 and 2024, were included, focusing on patient outcomes such as stroke recurrence, functional recovery, and safety measures. The findings consistently demonstrated that DAPT, particularly combinations like aspirin with clopidogrel or cilostazol, significantly reduced stroke recurrence and improved functional outcomes as compared to monotherapy, without a notable increase in major bleeding risk. Timing and duration of therapy were identified as critical factors, with early initiation and prolonged DAPT showing promising results in high-risk populations, including those with intracranial arterial stenosis or large artery atherosclerosis. Genetic polymorphisms, such as CYP2B6 variants, further influenced treatment efficacy, highlighting the potential for ",,,auto_pubmed,scipeerai_collector_v1,pmid:40018495
+SPB-0039,10.1038/s41598-025-94968-1,Identification of RNA processing factor LSM5 as a new adverse biomarker in nasopharyngeal carcinoma.,"Lin Ting, Deng Linyu, Liu Siyu, Chen Yan, Tang Yinggang, et al.",2025,Scientific reports,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Dysregulated RNA processing is crucial in nasopharyngeal carcinoma (NPC) progression. Our research aimed to evaluate the prognostic values of RNA-processing genes (RPGs) in NPC through bioinformatic analysis of the GSE12452 and GSE102349 datasets, identifying differentially expressed RNA-processing genes (DE-RPGs). A prognostic model was developed using univariate and multivariate Cox analysis, with effectiveness assessed by ROC analysis. The correlation between risk scores, immune characteristics, and chemotherapy sensitivity was also analyzed. Model gene expression was validated by RT-qPCR, Western Blot, and immunohistochemistry, alongside functional assays. Bioinformatics indicated that RNA binding motif protein 20 (RBM20) and LSM5 are prognostic RPGs, with the ROC curve confirming their predictive ability for survival. Significant differences in drug sensitivity were noted between high- and low-risk groups. Experimental validation showed LSM5 is overexpressed in NPC tissues, correl",,,auto_pubmed,scipeerai_collector_v1,pmid:40121338
+SPB-0040,10.1111/tpj.70107,Auxin-responsive OsMADS60 negatively mediates rice tillering and grain yield by modulating OsPIN5b expression.,"Wu Wenhao, Li Hongyu, Zhou Qian, Wu Bowen, Huang Weiting, et al.",2025,The Plant journal : for cell and molecular biology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Rice tillering determines grain yield, yet the molecular regulatory network is still limited. In this study, we demonstrated that the transcription factor OsMADS60 promotes the expression of the auxin transporter OsPIN5b to affect auxin distribution and inhibit rice tillering and grain yield. Natural variation was observed in the promoter region of OsMADS60, with its expression level negatively correlated with tiller number and inducible by auxin. Overexpression of OsMADS60 resulted in reduced tillers and grain yield, whereas CRISPR-mediated knockouts of OsMADS60 led to increased tillering and yield. OsMADS60 was found to directly bind the CArG motif [CATTTAC] in the OsPIN5b promoter, thereby upregulating its expression. Moreover, we found that auxin content in various tissues of OsMADS60 and OsPIN5b overexpression lines increased relative to the wild-type ZH11, whereas the auxin levels in mutant lines showed the opposite trend. Genetic analysis further confirmed that OsPIN5b acted dow",,,auto_pubmed,scipeerai_collector_v1,pmid:40089916
+SPB-0041,10.2174/011570159X349612241205065330,Withdrawn: Stable Gastric Pentadecapeptide BPC 157 as a Therapy of Severe Electrolyte Disturbances in Rats.,"Grubisic Marija Medvidovic, Strbe Sanja, Barisic Ivan, Balenovic Dijana, Stambolija Vasilije, et al.",2025,Current neuropharmacology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"The article has been withdrawn at the author's request from the website of the journal Current Neuropharmacology. Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused. The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submitting the article for publication the authors agree that the publishers have the legal right to take appropriate action against the authors, if plagiarism or fabricated information is discovered. By submitting a manuscript, the authors agree that the copyright of their article is tra",,,auto_pubmed,scipeerai_collector_v1,pmid:39865815
+SPB-0042,10.1186/s12894-025-01725-7,Efficacy of lactoferrin in preventing recurrent urinary tract infections in pregnant Egyptian women: a randomized controlled trial.,"Shoukry Ahmed, ElKassar Yasser, Hezagirwa Michaella K, El-Said Rehab",2025,BMC urology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Prevention of a very prevalent problem such as urinary tract infections (UTIs), is of utmost importance, particularly during pregnancy, in order to limit the irrational use of antibiotics. Lactoferrin (Lf) has proven in vivo and in vitro antibacterial actions, especially against Escherichia coli, which is the main causative organism of UTIs. The study question is, ""Does the administration of Lf to pregnant women with a history of RUTIs reduce the incidence of new episodes of UTIs during pregnancy?"". This was a randomized controlled study over 6 months that started from February 2024 to August 2024, conducted at the antenatal clinic of El-Shatby University Hospital, Alexandria, Egypt. The study included 220 pregnant women (14-24 weeks' gestation) who had experienced two or more UTI episodes in the previous six months. A negative urine culture right before enrollment was an inclusion criterion. Participants were randomly allocated into two groups; 110 women received a daily dose of 200 m",,,auto_pubmed,scipeerai_collector_v1,pmid:40264102
+SPB-0043,10.1039/d5sc06542a,Photo-generated radical mediated molecular luminescence enhancement.,"Song Jinming, Zhang Fengling, He Zhenyi, Zhou Lei, Cao Jingyu, et al.",2025,Chemical science,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Achieving rapid modulation of molecular luminescence under external stimuli remains a significant challenge in organic luminescent materials. Herein, we present a radical-mediated approach to achieve dynamic fluorescence switching. A series of benzil derivatives (BS, BZ, BD, and BQ) exhibit rapid transitions from nearly non-luminescent states to highly fluorescent states under continuous ultraviolet (UV) irradiation in solution. Notably, the absolute photoluminescence quantum yield of BS solution increased 41-fold, from 1.26% to 51.09%, after 330 s of 365 nm UV exposure. Mechanistic investigations reveal that this unique luminescence enhancement originates from UV-induced generation of aromatic carbonyl radicals. In general, molecules in solution undergo photodegradation with increasing irradiation time, resulting in a decrease in luminescence intensity. In contrast, we report a molecule whose luminescence intensity increases with increasing irradiation time, which is very rare. This w",,,auto_pubmed,scipeerai_collector_v1,pmid:41221119
+SPB-0044,10.1002/lary.32128,Functional but Not Structural Brain Changes After Olfactory Training in Women With COVID-19-Associated Olfactory Dysfunction.,"Li Zetian, Gebler Julia, Joshi Akshita, Xu Xinni, Thaploo Divesh, et al.",2025,The Laryngoscope,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Olfactory training (OT) is a recommended treatment for olfactory loss and has proven effective in clinical contexts, yet its effects on the central-nervous system remain unclear. This study aimed to investigate the functional and structural brain changes in patients with post-viral olfactory loss undergoing OT. Twenty patients with post-viral olfactory loss and 19 healthy controls underwent OT for 3 months. All participants were assessed using the Sniffin' Sticks test and magnetic resonance imaging (MRI). Voxel-based morphometry and olfactory bulb volumetry were performed on structural images. Presenting an unpleasant odor, n-butanol, in a canonical block design, functional MRI was performed using whole-brain and region of interest analyses. Patients with post-viral olfactory loss showed significant improvement following OT. Enhanced functional activations were observed in the orbitofrontal cortex and parahippocampus, while OT had little or no effects on brain structures. The present f",,,auto_pubmed,scipeerai_collector_v1,pmid:40152156
+SPB-0045,10.1038/s41598-025-96274-2,BMP2 expression in oral squamous cell carcinoma and its effects on SCC9 cell biological behavior.,"Xing Fuao, Liu Yimin, Tian Faming, Hou Xiaoli, Lian Qiangqiang, et al.",2025,Scientific reports,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"This study examined bone morphogenetic protein 2 (BMP2) expression in oral squamous cell carcinoma (OSCC) and its effects on the biological behavior of OSCC cells, along with potential underlying mechanisms. BMP2 expression in OSCC was analyzed using mRNA data from The Cancer Genome Atlas and Genomics Expression Omnibus Database (GEO). SCC9 cells were transfected in vitro with small interfering RNA targeting BMP2 (si-BMP2), a negative control sequence (si-NC), BMP2 plasmid, or empty plasmid (vector). After transfection, Cell Counting Kit-8 assays, colony formation, scratch wound healing, Transwell, flow cytometry, quantitative reverse transcription polymerase chain reaction, and Western blot analyses were conducted to assess changes in SCC9 cell behavior in response to altered BMP2 expression and to explore relevant signaling pathways.BMP2 upregulation promoted SCC9 cell proliferation, migration, and invasion; inhibited apoptosis; and activated the Smad1/5 and p38 signaling pathways. C",,,auto_pubmed,scipeerai_collector_v1,pmid:40185978
+SPB-0046,10.1016/j.lungcan.2025.108559,Antibody-drug conjugate components in association with the incidence of ADC-related interstitial lung disease: A systematic review and meta-analysis.,"Shao Tianyu, Yang Jiayao, Chen Jialu, Zhang Yao, Shou Liumei",2025,"Lung cancer (Amsterdam, Netherlands)",pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Antibody-drug conjugates (ADCs) have emerged as an innovative approach in cancer therapy. Although the incidence of ADC-related interstitial lung disease (ILD) is low, it remains a clinically significant and potentially fatal adverse event. This study focuses on evaluating the incidence of ADC-related ILD and examining how specific ADC components contribute to the risk of ILD. Five databases were conducted to identify clinical studies on ADC-related ILD published up to September 2024. The incidence of treatment-related adverse events was calculated by a random effects (RE) model. A total of 120 clinical studies involving 20,119 patients were included. The overall incidence of ADC-related ILD was 4.40 % (1215/20119) for all-grade and 2.35 % (603/20119) for grade ≥ 3 ILD. Among these, 2287 patients had hematologic tumors and 17,832 patients had solid tumors. Particularly, gastrointestinal cancers (12.81 %, 107/835), followed by lung cancer (9.70 %, 290/2991) were observed with a high inc",,,auto_pubmed,scipeerai_collector_v1,pmid:40311311
+SPB-0047,10.1007/s11882-025-01235-4,Restoring the Sense of Smell: A Systematic Review and Meta-Analysis of Biologic Therapies for Chronic Rhinosinusitis with Nasal Polyps.,"Pedersen Christian K, Backer Vibeke, Tidemandsen Jens Even, Høj Simon, Høxbro Marie, et al.",2025,Current allergy and asthma reports,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Smell loss is among the most debilitating symptoms of chronic rhinosinusitis with nasal polyps (CRSwNP). We aimed to synthesize current evidence on the smell-restoring efficacy of biologics, focusing on outcomes measured by psychophysical tests. Biologics mark a paradigm shift in the management of refractory CRSwNP, offering targeted, effective and safe treatment options. However, their relative impact on psychophysical smell outcomes remains uncertain. With several biologics now approved and real-world evidence emerging, a comprehensive evaluation is needed. This is a systematic review and meta-analysis of 8 RCTs (n = 2,024) and an additional review of 20 cohorts (n = 1,685). Among RCTs, biologic treatment produced a moderate to large pooled improvement in psychophysical smell scores (standardized mean difference, [SMD] = 0.72 (95% CI 0.32-1.13), p = 0.0004). The effect differed between drugs (χ² = 23.95, p < 0.0002). Dupilumab showed the largest improvements across four RCTs (SMD = 1",,,auto_pubmed,scipeerai_collector_v1,pmid:41261303
+SPB-0048,10.1111/sms.70119,The Copenhagen Adduction Exercise Effect on Sport Performance and Injury Prevention: A Systematic Review With Meta-Analysis.,"Quintana-Cepedal Marcos, de la Calle Omar, Diez-Solorzano Pedro, Sanchez-Martinez Beatriz, Crespo Irene, et al.",2025,Scandinavian journal of medicine & science in sports,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"The popularity of the Copenhagen Adduction Exercise (CAE) has risen in recent years. This review aims to evaluate the available evidence on the isolated use of the CAE for both performance enhancement and injury prevention. This systematic review included prospective interventional studies investigating the effect of the CAE on strength and conditioning and injury prevention outcomes. 15 studies were included, comprising randomized controlled trials (n = 4), cluster-randomized controlled trials (n = 6), and pre-post trials (n = 5). These studies assessed adduction and abduction strength, jump and sprint performance, core endurance, dynamic balance, adductor longus muscle thickness, and the seasonal prevalence of groin injuries. Meta-analyses of within-group changes and between-group comparisons were performed using standardized mean differences (SMDs) and relative risk (RR). The implementation of the CAE yielded large effect sizes for adduction (within-group SMD = 0.72, 95% CI = 0.41 t",,,auto_pubmed,scipeerai_collector_v1,pmid:40827942
+SPB-0049,10.1136/bjsports-2024-109541,The forgotten DOMS: recognising delayed muscle soreness in hand rehabilitation.,Tedeschi Roberto,2025,British journal of sports medicine,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,,,,auto_pubmed,scipeerai_collector_v1,pmid:40389289
+SPB-0050,10.1111/jocd.70291,The Use of Medium-Deep Peelings to Treat Melasma: A Case Series Study.,"Scardua Maria Tereza, Scardua Natália, Fernanda Ismail Maria, Junior Wilson Bambirra, Carpinteiro Inês Maria Candeias, et al.",2025,Journal of cosmetic dermatology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"To evaluate the efficacy and safety of medium-deep chemical peels for melasma in a diverse population using quantitative and subjective methodologies for comprehensive outcome assessment. A case series of 42 melasma region treatments was conducted from March 2023 to December 2024. Treatments included 30% phenol with 0.8% croton oil or a two-step protocol of 30% glycolic acid followed by 35% trichloroacetic acid (TCA) with 0.7% croton oil. Quantitative pigmentation analysis utilized the weighted skin intensity (WSI) ratio via Fiji ImageJ software. A panel of 20 experts conducted subjective evaluations based on standardized photographs, rating pigmentation reduction, skin tone uniformity, and overall appearance. Statistical analyses included the Wilcoxon signed-rank test and heatmap visualizations. Quantitative analysis showed significant improvements in pigmentation, with mean WSI values increasing from 78.99 ± 19.58 (untreated) to 88.33 ± 22.05 (treated; Z = -5.495), p < 0.001). Heatma",,,auto_pubmed,scipeerai_collector_v1,pmid:40820687
+SPB-0051,10.1016/j.jconrel.2025.02.054,Oxygen-supplying nanotherapeutics for bacterial septic arthritis via hypoxia-relief-enhanced antimicrobial and anti-inflammatory phototherapy.,"Jiang Huimei, Zhao Yifan, Lv Bai, Jiang Zijia, Cao Jie",2025,Journal of controlled release : official journal of the Controlled Release Society,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Bacterial septic arthritis, an inflammatory disease caused by bacterial infections, is often accompanied by the emergence of multidrug-resistant bacteria, making therapeutic treatment a formidable challenge. With the emergence of antibiotic resistance, research on antimicrobial photodynamic therapy (aPDT) has regained attention. However, insufficient singlet oxygen production due to the hypoxia in the infection microenvironment is recognized as a key limiting the efficacy of aPDT. Hence, in this study, we designed a bacteria-targeted liposomal nanoplatform (MCPL) to alleviate hypoxia in the infectious microenvironment and enhance aPDT for bacterial septic arthritis. The nanoplatform was developed by integrating the phototherapeutic agent CyI and small-sized Pt NPs into thermosensitive liposomes, with modification of maltohexose on the liposome surface. In vitro and in vivo studies showed that MCPL could specifically target bacterial cell membranes and be thermally activated to catalyti",,,auto_pubmed,scipeerai_collector_v1,pmid:39986475
+SPB-0052,10.31662/jmaj.2024-0437,"Retracted: Chronic Epipharyngitis Treated with Epipharyngeal Abrasion Therapy: Symptoms, Diagnosis, Pathogenesis, and Treatment Outcomes.","Harabuchi Yasuaki, Kumai Takumi, Nishi Kensuke, Tanaka Ayaki, Hotta Osamu, et al.",2025,JMA journal,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Chronic epipharyngitis is associated with a wide variety of symptoms, including local symptoms such as postnasal drip, sore throat, lump sensation of the pharynx, headache, chronic cough, nasal obstruction, tinnitus/ear fullness, chronic phlegm and dysphonia due to inflammation of the epipharynx, functional somatic symptoms such as chronic fatigue, dizziness, insomnia, brain fog, abdominal discomfort, and depression caused by dysfunction of the hypothalamus-limbic system via disturbances of vagal response and cerebrospinal fluid outflow, and distant organ symptoms such as immunoglobulin A nephropathy and palmoplantar pustulosis caused by the epipharyngeal lymphoid tissue as an etiologic organ. In the past, chronic inflammation in the epipharynx was difficult to prove by gross findings, now, direct observation of the epipharyngeal inflammation by endoscopy has become easier for the diagnosis. For the treatment of chronic epipharyngitis, epipharyngeal abrasive therapy (EAT), epipharyngea",,,auto_pubmed,scipeerai_collector_v1,pmid:40416015
+SPB-0053,10.1016/j.eurox.2025.100381,Could blastocysts derived from abnormal fertilized zygotes be used? A systematic review and meta-analysis.,"Wu Yiqing, Xue Jinglei, Tu Mixue, Liu Yifeng, Zhang Dan",2025,European journal of obstetrics & gynecology and reproductive biology: X,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Current guidelines advise against using embryos derived from mono-pronuclei (1PN) or non-pronuclei (0PN) zygotes for clinical purposes. Nevertheless, recent studies have demonstrated that 1PN and 0PN zygotes can lead to healthy births. This study aimed to investigate the pregnancy outcomes of 1PN and 0PN blastocysts. PubMed, EMBASE, Web of Science and Cochrane databases were searched up to 14 March 2024. Eligible studies enrolled participants transferring 0PN or 1PN blastocysts, with two pronuclei (2PN) blastocysts used as the control. Clinical pregnancy rate, miscarriage rate and live birth rate were the main outcomes. The results were presented as odds ratios (OR) with 95 % confidence intervals (CI) using random-effect models with the Mantel-Haenszel method. Additionally, a stratified analysis was conducted based on the type of fertilization. The Newcastle-Ottawa scale (NOS) was used to evaluate the quality of the included studies. In total, 270 articles were identified, with 16 ulti",,,auto_pubmed,scipeerai_collector_v1,pmid:40206393
+SPB-0054,10.7759/cureus.78137,Role of Statins in Reducing Cardiovascular Mortality: A Systematic Review of Long-Term Outcomes.,"Seth Bipasha, Okello David, Saad Ullah Syed, Yousaf Rabia, Alfalasi Shaikha B, et al.",2025,Cureus,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Cardiovascular diseases (CVDs) remain the leading cause of mortality worldwide, highlighting the critical need for effective preventive therapies. Statins, or HMG-CoA reductase inhibitors, are widely prescribed for their ability to lower low-density lipoprotein (LDL) cholesterol and reduce CV risk. This systematic review evaluates the long-term impact of statins on CV and all-cause mortality across diverse populations, including those with chronic kidney disease, chronic heart failure, and other comorbid conditions. A comprehensive search of major databases identified randomized controlled trials and large observational cohort studies with follow-up periods exceeding one year. Findings demonstrated significant reductions in CV mortality (hazard ratio (HR) range: 0.38-0.76) and all-cause mortality (HR range: 0.55-0.80) with statin therapy, particularly among high-risk groups, such as individuals with elevated LDL-C and moderate chronic kidney disease. Additional benefits were observed i",,,auto_pubmed,scipeerai_collector_v1,pmid:40018472
+SPB-0055,10.3389/fendo.2025.1634580,From molecular mechanism to plant intervention: the bidirectional regulation of inflammation and oxidative stress in bone aging.,"Li Qi, Zhao Xiumei, Wang Anning, Hang Tingting, Zhao Jianpeng, et al.",2025,Frontiers in endocrinology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"This article systematically elaborates the central role of inflammatory response and oxidative stress in osteoporosis (OP) and cartilage injury, and reveals the molecular mechanism by which the two damage bone homeostasis through NF-κB, RANKL and other signaling pathways. Studies have shown that plant natural products (such as hesperidin, curcumin, Epimedin B, etc.) can improve bone metabolism imbalance and delay the process of bone aging by regulating inflammatory factors (TNF-α, IL-1β) and antioxidant pathways (Nrf2/HO-1). Osteoporosis and cartilage damage promote each other to form a vicious cycle, and the intervention of plant active ingredients can target this common pathological process. Based on the current evidence, the strategy of combining anti-inflammation, anti-oxidation and mechanical regulation may provide a new direction for the prevention and treatment of bone aging-related diseases.",,,auto_pubmed,scipeerai_collector_v1,pmid:40704144
+SPB-0056,10.1007/s11695-025-07998-z,Postoperative Nausea and Vomiting After Metabolic Bariatric Surgery: a Comprehensive Review.,"Jumaev Nozim, Teshaev Oktyabr, Rajapov Azamat, Lim Irina",2025,Obesity surgery,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Metabolic bariatric surgery (MBS) has become an increasingly common treatment for morbid obesity and its comorbidities. Despite significant advances in surgical techniques and anesthesiological management, postoperative nausea and vomiting (PONV) remain frequent complications that significantly affect patient recovery. This review examines the epidemiology, pathophysiological mechanisms, risk factors, clinical features, prevention strategies, and treatment approaches for PONV in patients undergoing metabolic bariatric surgery. A systematic search was conducted in Cochrane Library, PubMed, and MEDLINE databases for relevant literature published between 2000 and 2024. Keywords included ""metabolic bariatric surgery,"" ""postoperative nausea and vomiting,"" ""PONV,"" ""laparoscopic gastric bypass,"" ""sleeve gastrectomy,"" ""PONV prevention,"" and ""PONV treatment."" Randomized controlled trials, prospective and retrospective cohort studies, systematic reviews, and meta-analyses were included. The inci",,,auto_pubmed,scipeerai_collector_v1,pmid:40531283
+SPB-0057,10.1016/j.cellsig.2025.111860,WITHDRAWN: LINC01614 enhances neural invasion and gastric cancer progression by stabilizing VCAM1 and activating the AKT/mTOR pathway.,"Liu Yujing, Li Qian, Wu Yongyou, Tang Hongjie, Zou Chen, et al.",2025,Cellular signalling,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,This article has been withdrawn at the request of the author(s) and/or editor due to an error in the publishing process. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/policies-and-standards/article-withdrawal.,,,auto_pubmed,scipeerai_collector_v1,pmid:40349810
+SPB-0058,10.1038/s41598-025-95865-3,Reducing PKCδ inhibits tumor growth through growth hormone by inhibiting PKA/CREB/ERK signaling pathway in pituitary adenoma.,"Chen Xi, Mao Jianyao, Zhou Liwei, Jiang Weichao, Li Zhangyu, et al.",2025,Scientific reports,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Patients with growth hormone-secreting pituitary adenoma (GHPA) often fail to exhibit the molecular signatures typically associated with tumorigenesis. This study investigates the role of protein kinase C delta (PKCδ) in modulating cell apoptosis, migration, invasion, and tumor growth in pituitary adenoma. We assessed the activation of the PKA/CREB/ERK signaling pathway and cell apoptosis through RT-qPCR and western blot analysis. Wound-healing and transwell assays were employed to evaluate cell migration and invasion. Combined treatment with rottlerin and phorbol 12-myristate 13-acetate (PMA) reversed the inhibition of the PKA/CREB/ERK signaling pathway, downregulated cell apoptosis, and reduced growth hormone secretion in GH3 cells. A decrease in the level of PKCδ also inhibited the PKA/CREB/ERK signaling pathway, reduced cell apoptosis, and suppressed the secretion of growth hormone. Notably, growth hormone reversed the decline in cell migration and invasion following PKCδ siRNA tre",,,auto_pubmed,scipeerai_collector_v1,pmid:40181069
+SPB-0059,10.1038/s41598-025-00222-z,"Novel prognostic biomarkers in small cell lung cancer reveal mutational signatures, genomic mutations, and immune implications.","Li Yuting, Song Chen, Wang Haijun, Di Wenyu, Chen Yangyang, et al.",2025,Scientific reports,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Small cell lung cancer (SCLC) is a highly malignant lung cancer subtype with a dismal prognosis and limited treatment options. This study aimed to identify new prognostic molecular biomarkers for SCLC and explore their immune-related implications for treatment strategies. We analyzed 200 SCLC samples via whole-exome sequencing (WES) and 313 samples by targeted sequencing. A smoking-related SBS4 mutational signature was linked to poorer prognosis and lower tumor mutational burden (TMB), while the APOBEC-mediated SBS13 signature was associated with better prognosis and higher TMB. We identified a molecular subtype with the worst outcomes and lowest TMB in both cohorts. Among 38 high-frequency mutated genes associated with SCLC prognosis, only UNC13A mutations were beneficial. Patients with UNC13A mutations had favorable immune infiltration and tumor immunogenicity. Additionally, TP53 splice site mutations were related to the worst survival outcomes. In conclusion, we discovered new molec",,,auto_pubmed,scipeerai_collector_v1,pmid:40320401
+SPB-0060,10.2147/IJGM.S523428,Effective Doses of Oliceridine Combined with Propofol for Painless Hysteroscopy: A Prospective Dose-Finding Study.,"Gao Liangliang, Tan Aiping, Wang Zehui, Wei Lei, Wang Xingshuang",2025,International journal of general medicine,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"The combination of oliceridine with propofol represents a new option for complete intravenous anesthesia in painless hysteroscopy. The purpose of this study was to determine the 95% effective dose (ED95) and the median effective dose (ED50) of oliceridine when combined with propofol for painless hysteroscopy. A total of 29 patients, aged between 18 and 60 years and classified as American Society of Anesthesiologists (ASA) I-II, were initially recruited for hysteroscopy. Subsequently, 26 of these patients were included in the final analysis. Before surgery, an intravenous dose of 0.02 mg/kg oliceridine, with a dose gradient of 0.002 mg/kg, was administered using Dixon's up-and-down method. Two minutes later, 2 mg/kg of propofol was administered. The oliceridine dosage for the following patient was increased by 0.002 mg/kg if the hysteroscopy failed (defined as poor cervical dilatation, problematic hysteroscopic placement, or a Ramsay Sedation Scale (RSS) score < 5 or any movement and fr",,,auto_pubmed,scipeerai_collector_v1,pmid:40421110
+SPB-0061,10.3389/fendo.2025.1606753,Meta-analysis of the synergistic effect of traditional Chinese medicine compounds combined with conventional Western medicine in the treatment of osteoporosis.,"Jin Huan, Huang Cai, Zhang Yan, Dong Ying, Xiong Qi, et al.",2025,Frontiers in endocrinology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"As a global public health problem, osteoporosis (OP) urgently requires better treatment strategies. This study systematically evaluated the synergistic effect of traditional Chinese medicine (TCM) compounds combined with conventional Western medicine (such as bisphosphonates and calcium) compared to Western medicine alone in the treatment of OP through a meta-analysis. Based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses and the Measurement Tool for Systematic Review Assessment guidelines, databases such as PubMed and Embase were systematically searched (as of March 2025), and 13 randomized controlled trials (RCTs), involving a total of 2,403 patients, were included. The integrated Chinese and Western medicine group showed significantly higher lumbar and femoral neck Bone mineral density (BMD) growth rates than the control group, alongside reduced pain visual analogue scale (VAS) scores. Mechanistically, the combination therapy synergistically modulated bone turn",,,auto_pubmed,scipeerai_collector_v1,pmid:40510481
+SPB-0062,10.1167/tvst.14.7.20,Effects of Chinese Acupoint Eye Exercise on Ocular Biological Parameters.,"Liu Yang, Li Wenjing, Li Lufan, Ren Yaoyao, Jiang Bin, et al.",2025,Translational vision science & technology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"This study aims to explore the effects of Chinese acupoint eye exercises on ocular vascular parameters and to understand its role in modulating blood flow dynamics after near-vision tasks. Fifty-five participants (110 eyes) from September through November 2023 randomized to four groups: the standard Chinese acupoint eye exercise group (SCAEE), sham acupoint eye exercise group (SAEE), simply eye closure group, and simply distance looking group (SDL). Ocular parameters, including retinal and choroidal thickness, perfusion area, and vessel density, were measured using Swept-source Optical Coherence Tomography. The impact of these exercises was evaluated through paired samples t-tests. All groups experienced an overall increase in retinal thickness, except for the SDL group. Significant thickening of the retinal nerve fiber layer was observed in SCAEE group, and SDL group. However, the outer retina layer showed the most significant thinning in SDL group. The perfusion area displayed a decr",,,auto_pubmed,scipeerai_collector_v1,pmid:40704879
+SPB-0063,10.1016/j.jbspin.2025.105915,WITHDRAWN: Weighing in on obesity and psoriatic arthritis - Time to move beyond association to robust randomised trials.,"Siebert Stefan, Sattar Naveed, Ferguson Lyn D",2025,Joint bone spine,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"The Publisher regrets that this article is an accidental duplication of an article that has already been published, https://doi.org/10.1016/j.jbspin.2025.105904. The duplicate article has therefore been withdrawn. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/policies-and-standards/article-withdrawal.",,,auto_pubmed,scipeerai_collector_v1,pmid:40316200
+SPB-0064,10.1016/j.virs.2025.04.002,WITHDRAWN: Comparative metatranscriptome analysis in gut reveals insignificant host or microbiota changes in SARS-related coronavirus naturally infected bats.,"Wang Qi, Mei Shi-Qiang, Dong Tian-Yi, Su Jia, Pan Yuan-Fei, et al.",2025,Virologica Sinica,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,The publisher regrets that this article has withdrawn. The full Elsevier Policy on Article Withdrawal can be found athttps://www.elsevier.com/about/policies-and-standards/article-withdrawal.,,,auto_pubmed,scipeerai_collector_v1,pmid:40204156
+SPB-0065,10.1371/journal.pone.0327255,Astragaloside IV combined with quercetin attenuates silica-induced pulmonary fibrosis by promoting autophagy and suppressing pyroptosis.,"Zhu Wenwen, Zhao Ningxia, Ma Yinghua, Zhang Wei, Ma Jiazi, et al.",2025,PloS one,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Silicosis, a prevalent occupational disease caused by exposure to silica particles, currently lacks effective treatment. Traditional Chinese medicine (TCM), with its millennia of clinical application, offers potential therapeutic solutions. This study aimed to investigate the therapeutic effects of astragaloside IV (ASV) combined with quercetin (QUE) in silicosis, particular focus on their possible mechanisms involving autophagy modulation and pyroptosis regulation. Rat silicosis models were established through silica particle exposure to evaluate the therapeutic effects of ASV and QUE coadministration over 28 days. We assessed pulmonary inflammatory and fibrotic markers while simultaneously analyzing autophagy and pyroptosis-related indicators to elucidate the underlying mechanism. The ASV and QUE combination therapy significantly ameliorated silicosis pathology, demonstrating marked anti-inflammatory effects through the reduction of tumor necrosis factor alpha (TNF-α), transforming g",,,auto_pubmed,scipeerai_collector_v1,pmid:40561127
+SPB-0066,10.1021/acs.est.4c12959,Lithium Levels in Umbilical Cord Blood from Two Cities in China: Indicating Unidentified Sources of Human Exposure.,"Li Yu, Peng Xianglian, Liu Nian, Guo Hua, Jia Yurong, et al.",2025,Environmental science & technology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"As lithium demand continues to grow, increasing environmental lithium concentrations pose potential health risks to sensitive populations, particularly pregnant women and fetuses. However, data on fetal lithium exposure and umbilical cord blood lithium concentrations in nonpolluted regions remain scarce. To address this gap, we monitored lithium concentrations in maternal and umbilical cord blood in Beijing and Changsha, and analyzed exposure sources using a one-compartment model. Significant regional differences were observed: in 2019 and 2021, the mean (±SD) of lithium concentrations in umbilical cord blood in Beijing were 13.05 ± 7.34 and 11.23 ± 2.56 μg/L, respectively, while in Changsha, a significantly lower level of 0.61 ± 0.64 μg/L was found. Model estimates indicated that umbilical cord blood lithium in Changsha primarily originated from cereal, vegetables, and drinking water. However, most of the lithium in Beijing's cord blood came from unidentified sources, likely anthropog",,,auto_pubmed,scipeerai_collector_v1,pmid:39993142
+SPB-0067,10.1097/GOX.0000000000007200,Exosome Therapy for Chronic Wound Healing.,"Basamage Lucas, Ahn Hee Jin, Choi Ho-Sung, Antonio Carlos Roberto, Alarcão Alessandro Louza, et al.",2025,Plastic and reconstructive surgery. Global open,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Chronic lower-extremity ulcers linked to diabetes, venous insufficiency, or smoking are difficult to heal because of impaired vascularity, persistent inflammation, and extracellular matrix dysfunction. Exosome therapy-a cell-free regenerative approach-may address these deficits by delivering proangiogenic and immunomodulatory cargo. We evaluated its clinical usage in a case series. Four adults (age 42-62 y) with ulcers present for 6 months or more and refractory to compression, debridement, and topical care received monthly topical applications of adipose-derived stem-cell exosomes (Exo-HL, Primoris International Co., Ltd., Seoul, Korea), 1 × 10<sup>12</sup> particles/mL; 0.1 mL/cm<sup>2</sup> wound area). Wounds were photographed and measured every 2-4 weeks; Doppler ultrasonography quantified arterial resistive index and venous reflux at baseline and 3-month intervals. Follow-up continued for up to 7 months. Median baseline ulcer area was 12.4 cm² (range, 4.8-26.1 cm²). All wounds sh",,,auto_pubmed,scipeerai_collector_v1,pmid:41050971
+SPB-0068,,WITHDRAWN: Self-reported dog vaccination practices in pet owners enrolled in the Dog Aging Project in the United States found most dogs were vaccinated according to veterinarians' recommendations.,"Ekakoro John E, Ruple Audrey, Renter David, Cernicchiaro Natalia",2025,Annals of epidemiology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,,,,auto_pubmed,scipeerai_collector_v1,pmid:40653127
+SPB-0069,10.1192/bjp.2024.250,Effect of ketamine on anxiety: findings from the Ketamine for Adult Depression Study.,"Mills Natalie T, Nikolin Stevan, Glozier Nick, Barton David, Baune Bernhard T, et al.",2025,The British journal of psychiatry : the journal of mental science,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Anxiety disorders and treatment-resistant major depressive disorder (TRD) are often comorbid. Studies suggest ketamine has anxiolytic and antidepressant properties. To investigate if subcutaneous racemic ketamine, delivered twice weekly for 4 weeks, reduces anxiety in people with TRD. The Ketamine for Adult Depression Study was a multisite 4-week randomised, double-blind, active (midazolam)-controlled trial. The study initially used fixed low dose ketamine (0.5 mg/kg, cohort 1), before protocol revision to flexible, response-guided dosing (0.5-0.9 mg/kg, cohort 2). This secondary analysis assessed anxiety using the Hamilton Anxiety (HAM-A) scale (primary measure) and 'inner tension' item 3 of the Montgomery-Åsberg Depression Rating Scale (MADRS), at baseline, 4 weeks (end treatment) and 4 weeks after treatment end. Analyses of change in anxiety between ketamine and midazolam groups included all participants who received at least one treatment (n = 174), with a mixed effects repeated me",,,auto_pubmed,scipeerai_collector_v1,pmid:39763417
+SPB-0070,10.1016/j.actpsy.2025.105884,Can table tennis protect the aging brain? A systematic review and meta-analysis in neurodegenerative diseases.,"Łosińska Kinga, Maszczyk Adam",2025,Acta psychologica,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Table tennis (TT) is an increasingly investigated intervention for supporting cognitive, motor, and psychosocial functions in older adults with neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), and dementia. However, evidence remains fragmented, and the effect sizes and reliability of TT-based programs remain unclear. Following PRISMA 2020 guidelines, a systematic search of four databases (PubMed, Scopus, Web of Science, SPORTDiscus) was conducted through June 30, 2025. Ten studies met inclusion criteria, with five eligible for quantitative synthesis. Random-effects meta-analyses (DerSimonian-Laird) were performed on cognitive and motor outcomes. Risk of bias was assessed using the JBI checklist, and certainty of evidence was graded using the GRADE framework. Out of 499 screened records, ten studies met the predefined eligibility criteria and were included in the systematic review. Of these, five studies provided sufficient statistical data for i",,,auto_pubmed,scipeerai_collector_v1,pmid:41197370
+SPB-0071,10.7759/cureus.78271,Minimally Invasive Approaches for High-Risk and Elderly Patients With Acute Cholecystitis: A Systematic Review of Techniques and Outcomes.,"Abdelmaseeh Mark, Mhmndar Asem, Siddiqa Ayesha, Ahamed Shoaib S, Sheraz Kanwal, et al.",2025,Cureus,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Acute cholecystitis is a prevalent condition marked by gallbladder inflammation, typically due to gallstone obstruction, and poses management challenges, particularly for high-risk and elderly patients. This systematic review compares the efficacy and safety of two minimally invasive approaches: percutaneous drainage methods, such as percutaneous cholecystostomy, and laparoscopic cholecystectomy (LC). A structured search of PubMed, MEDLINE, and Embase was conducted, yielding six randomized controlled trials that met the inclusion criteria. Findings suggest that percutaneous drainage combined with LC offers advantages in reducing operative time, hospital stay, and complication rates, particularly for high-risk patients, compared to LC alone. However, routine postoperative drainage after LC may contribute to prolonged hospital stays and increased postoperative pain without reducing morbidity. Advanced energy devices, such as harmonic scalpels, may further optimize surgical outcomes, thou",,,auto_pubmed,scipeerai_collector_v1,pmid:40026918
+SPB-0072,10.1016/j.ijbiomac.2025.140021,Astragalus polysaccharide reduces the severity of acute pancreatitis under a high-fat diet through enriching L. reuteri and propionate.,"Wang Qiang, Liu Xuxu, Du Zhiwei, Zheng Yi, Meng Ziang, et al.",2025,International journal of biological macromolecules,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Acute pancreatitis (AP) is a severe digestive disorder, worsened by a high-fat diet (HFD) through inflammation and gut microbiota disruption. Astragalus polysaccharides (APS), known for their anti-inflammatory properties, may alleviate HFD-induced exacerbation of AP by modulating gut microbiota. This study investigates the effect of APS on AP severity under a HFD (HAP). Results show that HFD significantly worsens AP, with elevated serum enzymes, pro-inflammatory cytokines, and pancreatic damage. Single-cell RNA sequencing revealed increased ICAM1<sup>+</sup> neutrophils and activation of the NF-κB/necroptosis pathway in HAP mice. Treatment with APS reduced neutrophil infiltration, downregulated NF-κB, and suppressed necroptosis. APS also restored gut microbiota balance, boosting Lactobacillus reuteri (L. reuteri) and propionate (PA) levels. Interventions with L. reuteri or PA reduced HAP severity, with combined treatment showing synergistic effects. These findings suggest that the prot",,,auto_pubmed,scipeerai_collector_v1,pmid:39837455
+SPB-0073,10.7759/cureus.78497,Effects of Dietary Fiber Interventions on Glycemic Control and Weight Management in Diabetes: A Systematic Review of Randomized Controlled Trials.,"Abdi Syed Ali Hussein, Abdi Syed Imran Ali, Ali Mohamed H, Balani Noor A, Balani Nazik A, et al.",2025,Cureus,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"This systematic review explores the impact of dietary fiber interventions on glycemic control and weight management in individuals with diabetes or at risk for diabetes. A comprehensive search was conducted across PubMed, Embase, and Cochrane Library following the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines, identifying randomized controlled trials published in the last five years. Ten studies met the inclusion criteria, evaluating various types of dietary fiber, including soluble, insoluble, viscous fiber, and resistant starch. The findings demonstrated significant improvements in key glycemic markers such as fasting plasma glucose, glycated hemoglobin (HbA1c), and postprandial glucose levels, as well as weight management outcomes such as reductions in body weight and waist circumference. Secondary benefits included improvements in lipid profiles, insulin sensitivity, and gut microbiota composition. The quality assessment revealed a low risk ",,,auto_pubmed,scipeerai_collector_v1,pmid:40051945
+SPB-0074,10.1038/s41598-025-86575-x,Rechallenge therapy versus tyrosine kinase inhibitor (TKI) for advanced metastatic colorectal cancer: a retrospective study.,"Liu Chenming, Chen Jintao, Liu Yuxing",2025,Scientific reports,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Currently, the standard third-line treatment options for advanced metastatic colorectal cancer (mCRC) include regorafenib, fruquintinib, and trifluridine/tipiracil (TAS-102), but these drugs have limited clinical efficacy. This study aims to evaluate the efficacy and survival outcomes of tyrosine kinase inhibitor (TKI) versus chemotherapy rechallenge in third-line treatment for advanced mCRC patients. From January 2019 to December 2022, 107 patients met the inclusion criteria. After 1:1 matching, there were 34 patients in both the TKI and rechallenge groups. Cox regression analysis was performed to identify independent predictive factors. The result indicated that Eastern Cooperative Oncology Group (ECOG) score of 0-1 (hazard ratio [HR] = 0.03, 95% confidence interval [CI]: 0.01-0.17; P < 0.001) and chemotherapy rechallenge (HR = 0.43, 95% CI: 0.23-0.79; P = 0.007) were independent protective factors for overall survival (OS). Patient-Generated Subjective Global Assessment (PG-SGA) sco",,,auto_pubmed,scipeerai_collector_v1,pmid:39905022
+SPB-0075,10.1038/s41598-025-87556-w,Identification of novel IL17-related genes as prognostic and therapeutic biomarkers of psoriasis using comprehensive bioinformatics analysis and machine learning.,"He Xingling, Huang Jingjing, Ma Hanying, Ma Zhujun, Huang Changzheng, et al.",2025,Scientific reports,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Psoriasis is a common chronic skin disorder with a polygenic background. It is widely acknowledged that Th17/IL-17A axis plays a key role in the pathogenesis of psoriasis. However, numerous regulatory genes upstream of the pathway remain undiscovered, creating a knowledge gap in our understanding of the genetic aspects of the Th17/IL-17A axis. In this study, we employed machine learning algorithms to identify three target genes associated with psoriasis: CCR7, IL2RG, and PLEK. The validation of these genes was carried out in specimens from psoriatic patients. In vivo, investigations assessed the relationship between these three genes and IL-17A-related inflammation and their connection to psoriatic phenotypes. To further confirm the significance of the newly discovered gene, PLEK, we performed experiments involving the blockade of its expression. Our bioinformatics analysis revealed three novel genes closely linked to psoriasis: CCR7, IL2RG, and PLEK. These genes exhibited upregulated ",,,auto_pubmed,scipeerai_collector_v1,pmid:40175394
+SPB-0076,10.1530/EC-25-0723,RETRACTION: Comparative efficacy of semaglutide versus liraglutide on weight loss and glycaemic control.,"Ullah Hashmat, Khan Zahid Ullah, Wazir Asif, Khan Usman, Rehman Anees Ur, et al.",2026,Endocrine connections,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,,,,auto_pubmed,scipeerai_collector_v1,pmid:41532579
+SPB-0077,10.1371/journal.pone.0321032,RETRACTED: Cardiovascular and mortality outcomes of DPP-4 inhibitors vs. sulfonylureas as metformin add-on therapy in patients with type 2 diabetes: A systematic review and meta-analysis.,"Hasan Refli, Chugaeva Uliana Y, Mohammadian Mahdi, Zamanifard Somayeh, Mohammadian-Hafshejani Abdollah",2025,PloS one,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Type 2 diabetes significantly increase the risk of cardiovascular disease and mortality. This systematic review and meta-analysis compared cardiovascular and mortality outcomes in type 2 diabetes patients receiving dipeptidyl peptidase-4 inhibitors (DPP-4is) plus metformin versus sulfonylureas (SUs) plus metformin as add-on therapy. PubMed, Web of Science, Cochrane Central Register of Controlled Trials, Embase, Google Scholar, and Scopus were searched through January 1, 2025, for studies comparing DPP-4is plus metformin versus SUs plus metformin in type 2 diabetes patients. Outcomes of interest were major adverse cardiovascular events and all-cause mortality. Heterogeneity was assessed using Cochran's Q test and I2 statistic. Publication bias was evaluated with Begg's and Egger's tests. Study quality was assessed with the Jadad scale (for randomized controlled trials) and the Newcastle-Ottawa Scale (for observational studies). Twenty-seven studies (2012-2024), encompassing 1,505,821 pa",,,auto_pubmed,scipeerai_collector_v1,pmid:40323973
+SPB-0078,10.1186/s13018-025-05600-x,Shoulder range of motion and strength in beach tennis athletes compared to volleyball and tennis players: implications for injury risk and performance.,"Ramos Ana Paula, Secchi Leonardo Luiz Barretti, Migliorini Filippo, Maffulli Nicola, Okubo Rodrigo",2025,Journal of orthopaedic surgery and research,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Beach tennis (BT) combines elements of tennis, volleyball, and badminton, attracting a diverse global following. Despite its popularity, research on its link to shoulder injuries remains limited. This study investigates shoulder characteristics among BT athletes, volleyball players, and tennis athletes to identify potential differences and inform injury prevention strategies. A cross-sectional analysis was performed to assess shoulder range of motion (ROM) and rotator cuff strength in 65 athletes using an online questionnaire and biomechanical assessments. Volleyball players demonstrated superior shoulder ROM compared to tennis and BT athletes, while tennis players exhibited a greater difference in internal rotation between sides. Additionally, volleyball athletes displayed greater external rotation strength on the dominant side than tennis players, with BT athletes also exhibiting significant strength advantages. These findings emphasise the distinct demands of BT and highlight the ne",,,auto_pubmed,scipeerai_collector_v1,pmid:40269929
+SPB-0079,10.1159/000546077,"Oral Drospirenone/Estetrol as Rapid and Random Start Endometrial Preparation before Office Hysteroscopic Polypectomy: A Multicenter, Prospective, Randomized Controlled Trial.","Etrusco Andrea, Agrifoglio Vittorio, Chiantera Vito, Russo Giuseppe, Golia D Apos Augè Tullio, et al.",2026,Gynecologic and obstetric investigation,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Endometrial preparation provides significant surgical benefits prior to hysteroscopic procedures. However, there is still no consensus on the optimal presurgical protocol. Although there is evidence on rapid preparation, there are currently no studies on rapid endometrial preparation using combined oral contraceptives initiated at a ""random"" time in the menstrual cycle. The aim of the present trial was to evaluate the use of oral drospirenone/estetrol in random start rapid preparation of endometrium before office hysteroscopic polypectomy. In this multicenter, prospective, randomized controlled trial, 80 women scheduled for polypectomy were randomly assigned to intervention (n = 40) or control (n = 40) groups. The intervention group received oral drospirenone/estetrol (3 mg/14.2 mg/day) for 14 days, starting at any menstrual cycle point (random start). Controls underwent polypectomy on cycle days 8-11 without any prior pharmacological intervention. Pre- and post-procedure, endometrial ",,,auto_pubmed,scipeerai_collector_v1,pmid:40319875
+SPB-0080,10.1002/bcp.70249,Effects of different antihypertensive drug classes on central and ambulatory blood pressure in resistant hypertension: A randomized clinical trial.,"Yugar-Toledo Juan Carlos, Minari Tatiana Palotta, de Mello Priscilla Galisteu, do Espirito Santo Cestario Elizabeth, de Azevedo Rubio Tatiane, et al.",2026,British journal of clinical pharmacology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"This study compares sequential nephron blockade (SNB) and renin-angiotensin system sequential blockade (RASSB) in patients with resistant hypertension (RHTN), evaluating central systolic pressure, arterial stiffness, pulse pressure (PP) and ambulatory blood pressure monitoring (ABPM). Seventy-two RHTN patients were randomly assigned to SNB (n = 35, 22 females, 13 males) or RASSB (n = 37, 22 females, 15 males). SNB included multiple diuretics (furosemide, spironolactone, hydrochlorothiazide) to enhance natriuresis and counter intra-renal compensatory mechanisms. RASSB employed stepwise renin-angiotensin system blockade using lisinopril, bisoprolol and losartan, even in patients already on valsartan. Office blood pressure reductions were significant in both groups (P < 0.0001). SNB: systolic blood pressure (SBP) from 174.5 to 127.0 mmHg, diastolic blood pressure (DBP) from 105.3 to 78.11 mmHg. SBP from 178.4 to 134.4 mmHg, DBP from 102.7 to 77.33 mmHg. ABPM confirmed 24-h reductions (P <",,,auto_pubmed,scipeerai_collector_v1,pmid:40859651
+SPB-0081,10.7759/cureus.75902,Outcomes of Direct-Acting Antivirals Versus Interferon-Based Therapy in Chronic Hepatitis C Infection.,"Chowdhury Ratna, Rashid Wardah, Singh Taranpreet, Rehman Abdur, Daterdiwala Nida F, et al.",2024,Cureus,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"This systematic review evaluates the outcomes of direct-acting antivirals (DAAs) compared to interferon-based therapies in patients with chronic hepatitis C infection. DAAs consistently demonstrate higher sustained virologic response (SVR) rates and better safety profiles across various patient populations, including those with cirrhosis and treatment-experienced individuals. The studies included highlight the superior efficacy of DAAs, with fewer adverse events such as anemia and fatigue, making them more tolerable and suitable for long-term treatment. These findings reinforce the clinical importance of DAAs as the standard of care for managing hepatitis C virus (HCV), particularly in special populations. Although interferon-based therapies remain relevant in resource-limited settings, this review emphasizes the need for broader access to DAAs to improve global health outcomes and reduce HCV-related morbidity and mortality.",,,auto_pubmed,scipeerai_collector_v1,pmid:39830527
+SPB-0082,10.1002/fsn3.70424,"Causal Relationship Between Diet, Lipids, Immune Cells, and Chronic Fatigue Syndrome: A Two-Mediation Mendelian Randomization Study.","Li Jixu, Qin Qi, Zhu Yiran, Qian Yulu, Yin Jialu, et al.",2025,Food science & nutrition,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Chronic fatigue syndrome (CFS) is a disorder characterized by severe unexplained fatigue and is associated with various factors including infections, immune responses, genetics, and environmental influences. However, the underlying mechanisms and possible interventions for CFS remain unclear. We used a two-mediated MR method to investigate causal relationships between diet, lipid levels, immune cells, and CFS. Our findings suggest that certain lipids, specifically low-density cholesterol, apolipoprotein E, and apolipoprotein B, contribute to CFS development. Conversely, high-density lipoprotein cholesterol and apolipoprotein A1 may delay the onset of the syndrome. Additionally, we explored how lipids affect fatigue through immune cell mediation. Factors, such as hematopoietic stem cell absolute count, the percentage of CD3-natural killer lymphocytes, and IgD presence on IgD+ CD38+ B cells may mediate the causal pathway linking lipids to CFS. Furthermore, we examined the relationship be",,,auto_pubmed,scipeerai_collector_v1,pmid:40552329
+SPB-0083,10.7759/cureus.83757,"The Impact of Sleep Deprivation on Brain Fog, Cognitive Decline, and Cardiovascular Risk in Young Adults.","Younas Aimen, Vayolipoyil Sarath, Raghib Shaheera, Bano Sher, Wandala Abali, et al.",2025,Cureus,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Introduction Sleep deprivation is an escalating public health concern among young adults, as it impairs cognitive function and increases the risk of cardiovascular disease (CVD). Existing studies have linked chronic sleep deficiencies to mental confusion, reduced cognitive performance, and early signs of cognitive decline. Research also indicates that inadequate sleep contributes to metabolic dysregulation and autonomic system instability, both of which elevate cardiovascular risk. However, the overall effects of sleep deprivation on cognitive function and cardiovascular markers in young adults require further exploration. This study aims to examine the relationship between sleep deprivation, brain fog, early cognitive decline, and cardiovascular risk factors in this population. Methods This cross-sectional study involved 300 participants aged 18-30 from Pakistan and various other countries. Participants were selected using non-probability purposive sampling. Data were collected using ",,,auto_pubmed,scipeerai_collector_v1,pmid:40486440
+SPB-0084,10.1038/s41598-025-97826-2,Minimally invasive robotic ureteral reconstruction using endoscopic submucosal dissection harvested colorectal mucosa graft for ureteral stricture.,"Nie Haihang, Yu Yali, Chen Xiubing, Zhou Jingkai, Li Xianglin, et al.",2025,Scientific reports,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"To evaluate the feasibility and safety of using colorectal mucosal grafts (CMG) harvested via endoscopic submucosal dissection (ESD) for ureteral reconstruction in patients with ureteral stricture. Eight patients with ureteral stricture underwent robotic ureteral reconstruction using CMG harvested by ESD. Preoperative assessments included clinical history, physical examination, and various imaging studies. The ESD procedure was performed with standard precautions to obtain sufficient graft material. Postoperative follow-up involved endoscopic examinations and retrograde pyelograms to assess colorectal complication and ureteral patency. The average age of patients was 44 years, and the median BMI was 24.6 kg/m². The causes of stricture included ureteral stones, urinary tract infections, and ureteral polyps. The median stricture length was 3.5 cm. The average size of the harvested CMG was 4 × 2.4 cm. The success rate of the grafting procedure was 100%, with no gastrointestinal complicati",,,auto_pubmed,scipeerai_collector_v1,pmid:40216947
+SPB-0085,10.1177/07067437241307902,WITHDRAWN-Administrative Duplicate Publication: Substance Use and Concurrent Disorders: Current Context and the Need for Treatment Integration.,"Hendershot Christian S, Le Foll Bernard",2025,Canadian journal of psychiatry. Revue canadienne de psychiatrie,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,,,,auto_pubmed,scipeerai_collector_v1,pmid:39763227
+SPB-0086,10.1016/j.bbrc.2025.151568,The regulatory roles of plant miRNAs in biotic stress responses.,"Jiang Jia, Zhang Yu, Liu Jing, Zhang Hongyan, Wang Tian",2025,Biochemical and biophysical research communications,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Throughout their life cycle, plants are inevitably confronted with various challenges imposed by adverse environmental conditions, including both biotic and abiotic stresses. To adapt to these environmental fluctuations, plants have evolved a highly efficient regulatory mechanism, in which microRNAs (miRNAs) play pivotal roles. miRNAs are a class of 20-24 nucleotide non-coding RNAs generated from MIR genes, which regulate gene expression at the post-transcriptional level through mRNA degradation or translational repression. Over the past decades, accumulating evidence has demonstrated that miRNAs serve as master regulators in plant responses to biotic stresses, such as those caused by bacteria, fungi, oomycetes, viruses, nematodes, and insects. In this review, we summarize recent advances in miRNA biogenesis and highlight the regulatory roles of plant miRNAs in biotic stress tolerance. Additionally, we discuss future directions of miRNA research.",,,auto_pubmed,scipeerai_collector_v1,pmid:40043612
+SPB-0087,10.1142/S0192415X25500831,Therapeutic Prospects of Ursolic Acid in Colorectal Cancer: Modulation of the Wnt/β-Catenin Signaling Pathway and Gut Microbiota Composition.,"Zhao Hui, Jin Miaoxin, Qiao Jingyi, Tian Shuo, Cao Lihua, et al.",2025,The American journal of Chinese medicine,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"This investigation is designed to delineate the antineoplastic properties of ursolic acid against colorectal cancer and to elucidate underlying molecular mechanisms, including its influence on gut microbiota homeostasis as assessed by alpha/beta diversity and functional profiling. The study initially treated HCT116 and SW480 colorectal cancer cell lines with ursolic acid at concentrations ranging from 0 to 90 μM to evaluate its impact on cell proliferation. Building on this, the researchers re-exposed the colorectal cancer cells to ursolic acid at 5 μM, 10 μM, and 20 μM for 24[Formula: see text]h to comprehensively assess its effects on key cellular processes such as migration, colony formation, apoptosis, and cell cycle regulation. Additionally, the same concentrations (5 μM, 10 μM, and 20 μM) were used to re-expose the cells for 24[Formula: see text]h to evaluate the modulation of the Wnt/β-catenin signaling pathway by ursolic acid. In the in vivo experiments, based on previously pub",,,auto_pubmed,scipeerai_collector_v1,pmid:40884804
+SPB-0088,10.7759/cureus.80817,Efficacy and Safety of Peptide Receptor Radionuclide Therapy for the Treatment of Pancreatic Neuroendocrine Tumors: A Systematic Review and Meta-Analysis of Comparative Studies.,"Zhao Jun, Pei Xiaxia, Li Yumin",2025,Cureus,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Peptide receptor radionuclide therapy (PRRT) showed promising potential in the management of patients with pancreatic neuroendocrine tumors (pNETs). However, there is still a lack of evidence on its relative efficacy and safety compared with other treatment options. This review aims to synthesize the existing evidence on the efficacy and safety of PRRT for pNETs compared to different treatments. An electronic search was conducted from inception to May 2024. Comparative studies, including randomized controlled trials (RCTs), cohort studies, and case-control studies, that focused on the use of PRRT for treating pNETs were included. Efficacy outcomes included disease control rate (DCR), complete response (CR), partial response (PR), stable disease (SD), progression-free survival (PFS), and overall survival (OS). Safety outcomes were grade 3-4 hematological and renal toxicity and adverse events (AEs). Nine studies met the inclusive criteria. Among them, only one (11.1%) study was an RCT. M",,,auto_pubmed,scipeerai_collector_v1,pmid:40190903
+SPB-0089,10.1016/j.urology.2025.05.003,Association Between Kidney Stones and Subsequent Risk of Upper Tract Urothelial Carcinoma: A Systematic Review and Meta-Analysis.,"Bhojani Naeem, Chen Kelven W, Miller Larry E, Bhattacharyya Samir, Chew Ben H, et al.",2025,Urology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"To evaluate the association between a history of kidney stones and the subsequent risk of upper tract urothelial carcinoma (UTUC). We systematically searched Medline and Embase for observational studies reporting risk estimates of UTUC in adults with versus without a history of kidney stones. A random-effects meta-analysis was performed to calculate the pooled risk ratio (RR) with 95% confidence interval. The influence of individual studies on meta-analysis estimates was assessed by sequentially removing one study at a time from the meta-analysis. Seven studies (four cohort, three case-control) comprising 391,998 subjects were included in the meta-analysis. A history of kidney stones was associated with a significantly higher risk of developing UTUC (RR = 2.42; 95% confidence interval: 1.72, 3.41; P <.001; I<sup>2</sup> = 85%). The one-study removed sensitivity analysis demonstrated that no single study significantly influenced the meta-analysis results, with the RR ranging from 2.18 t",,,auto_pubmed,scipeerai_collector_v1,pmid:40349787
+SPB-0090,10.1016/j.ijbiomac.2025.141683,The role of cyclin dependent kinase molecules in the pathogenesis and immune cell infiltration of TNBC in silicosis: Based on core stem cell related genes TPX2 and CCNA2.,"Zhou Yu, Zeng Huifang, Ye Li, Wang Jin, Feng Guangqing, et al.",2025,International journal of biological macromolecules,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Silicosis is a pulmonary fibrotic disease caused by long-term inhalation of silica dust. CDKs regulate the process of cell cycle by binding with cyclin. This study revealed the role of cyclin-dependent kinase molecules in the pathogenesis of TNBC in silicosis and analyzed its influence on immune cell infiltration. By retrospective analysis of clinical samples from silicosis patients and TNBC patients, we evaluated the expression level of CDKs molecules. Then, the effect of silica dust exposure on breast cancer cell cycle was simulated using in vitro cell culture technology, and the expression changes of TPX2 and CCNA2 genes were observed. Immunohistochemical techniques were used to detect the infiltration of immune cells in silicosis and TNBC tissue samples, and to analyze its correlation with the expression of CDKs. The findings from the conducted research indicated that there was a significant elevation in the expression levels of cyclin-dependent kinases, or CDKs, in patients diagno",,,auto_pubmed,scipeerai_collector_v1,pmid:40037461
+SPB-0091,10.1016/j.lfs.2025.123799,A novel approach to bladder dysfunction induced by bladder outlet obstruction: Low-intensity extracorporeal shock wave therapy promotes bladder regeneration.,"Wu Sheng-Tang, Juan Tai-Jui, Lu Jian-He, Chueh Kuang-Shun, Mao Jing-Wen, et al.",2025,Life sciences,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Bladder outlet obstruction (BOO) leads to bladder structural and functional changes, including elevated detrusor contractile pressure, detrusor hypertrophy, fibrosis, and impaired contractility. Currently, no effective therapeutic strategy for BOO-induced bladder dysfunction. This study investigated whether low-intensity extracorporeal shock wave therapy (LiESWT) could improve bladder function by promoting detrusor contractility, urothelial proliferation, angiogenesis, and neurogenesis in a rat model of partial BOO (PBOO). Male Sprague-Dawley rats were divided into sham and PBOO groups for 4 or 8 weeks, with or without LiESWT once or twice weekly for 4 weeks. Urodynamic function, bladder histology, and the molecular mechanism were assessed. Compared to sham group, PBOO rats displayed wall hypertrophy, overdistension, mucosal damage, interstitial fibrosis, and altered microvascular patterns. However, LiESWT improved bladder structure, contractility, urothelial proliferation, tight junct",,,auto_pubmed,scipeerai_collector_v1,pmid:40505832
+SPB-0092,10.3389/fendo.2025.1639261,Lang-chuang-ding restores bone homeostasis in systemic lupus erythematosus associated osteoporosis by targeting NF-κB signaling: a network pharmacology and experimental study.,"Luo Huan, Zhou Huiqing, Shen Shuchao, Zeng Lingfeng, Ruan Hongfeng",2025,Frontiers in endocrinology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Systemic lupus erythematosus (SLE) is frequently associated with secondary osteoporosis (OP), substantially compromising patients' quality of life. Although Lang-chuang-ding (LCD), a traditional Chinese medicine formulation, has demonstrated efficacy in suppressing SLE progression, its therapeutic potential for SLE-associated OP remains uninvestigated. This study investigated the therapeutic effects and underlying pharmacological mechanisms of LCD on SLE-associated OP through in vivo experimental validation using MRL/lpr mouse model in conjunction with network pharmacology analysis. Our findings demonstrated that LCD significantly attenuated bone loss in the distal femur by improving bone morphometric parameters, including bone mineral density (BMD), trabecular number (Tb.N), and trabecular bone separation (Tb.Sp), while simultaneously suppressing osteoclast activity and promoting osteogenesis. Network pharmacological analysis identified 63 overlapping targets among LCD components, SLE",,,auto_pubmed,scipeerai_collector_v1,pmid:40810073
+SPB-0093,10.2807/1560-7917.ES.2026.31.2.2500993,"Moderate protection from vaccination against influenza A(H3N2) subclade K in Beijing, China, September to December 2025.","Shen Ying, Zhang Daitao, Feng Zhaomin, Ma Chunna, Shi Weixian, et al.",2026,Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"During the early 2025/26 influenza season, influenza A(H3N2) subclade K rapidly predominated in Beijing, China. Using a test-negative design, we estimated influenza vaccine effectiveness (VE) among influenza-like illness outpatients tested between September and December 2025. Among 9,579 participants, sequencing of 316 randomly selected A(H3N2)-positive samples showed 84.8% were subclade K, and antigenic analysis of 65 viruses indicated antigenic divergence. Despite this, adjusted VE against laboratory-confirmed influenza was 41.3% (95% CI: 29.2 to 51.3), indicating moderate protection during this subclade K-dominated season.",,,auto_pubmed,scipeerai_collector_v1,pmid:41540926
+SPB-0094,10.2147/IJWH.S542758,Research Progress and Clinical Implications of Generative Artificial Intelligence in Perinatal Health Care for Advanced Maternal Age Pregnant Women.,"Tang Shasha, Zhao Shihong",2025,International journal of women's health,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"To analyze the current application status, technical characteristics, and challenges of Generative Artificial Intelligence (Generative AI) in perinatal health care for advanced maternal age pregnant women and explore targeted optimization strategies. A systematic literature review was conducted by searching PubMed, Web of Science, CNKI, and Wanfang Data from January 2020 to April 2025. Studies were included if they focused on Generative AI applications in perinatal care for women aged ≥35 years; 78 eligible studies (42 Chinese, 36 international) were finally included, covering technical applications, clinical validation, and ethical governance. We summarized the applications of Generative AI in risk prediction, personalized management, and remote monitoring, and analyzed issues related to data governance, technical limitations, resource allocation, and ethical supervision. Generative AI improves healthcare efficiency by integrating multiple data sources for model construction, planning",,,auto_pubmed,scipeerai_collector_v1,pmid:40988772
+SPB-0095,10.1210/endrev/bnaf001,Effects of Maternal Vitamin D Supplementation on Childhood Health.,"Svensson Nanna S, Volqvartz Tabia, Vestergaard Anna Louise, Vestergaard Esben T, Larsen Agnete, et al.",2026,Endocrine reviews,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Vitamin D deficiency during pregnancy is associated with an increased risk of health issues in the offspring. Accordingly, recent Endocrine Society guidelines strongly support supplementation in pregnancy, also underlining that without consensus on optimal maternal vitamin D levels, routine screening is currently irrelevant. Knowledge of organ-specific effects of vitamin D and its association with maternal vitamin D status may aid in optimizing vitamin D supplementation. This systematic review outlines the proposed next-generation effects of vitamin D supplementation ≥400 IU/d and explores whether such effects are attributed to a specific maternal vitamin D level obtained during pregnancy. A systematic literature search was conducted in PubMed and Embase according to the PRISMA guidelines, focusing on health outcomes from 10 days postpartum and beyond. Of the 2383 screened articles, 39 were included. In 11 of 16 studies, vitamin D supplementation reduced respiratory tract infections in",,,auto_pubmed,scipeerai_collector_v1,pmid:39834161
+SPB-0096,10.1111/ans.70096,Enteral nutrition versus parenteral nutrition in the management of postoperative pancreatic fistula following pancreaticoduodenectomy: a prospective observational study.,"Kodali Rohith, Parasar Kunal, Anand Utpal, Anwar Saad, Saha Bijit, et al.",2025,ANZ journal of surgery,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Postoperative pancreatic fistula (POPF) presents a significant challenge to oral intake after pancreaticoduodenectomy (PD). Strategies such as enteral feeding via nasojejunal tube, feeding jejunostomy (FJ), and total parenteral nutrition (TPN) are commonly used to optimize postoperative nutrition. However, the routine use of FJ in PD remains controversial. This study assesses the effectiveness of enteral feeding versus TPN in the management of POPF. A prospective observational study was conducted on 100 patients undergoing classical PD at a tertiary care centre in eastern India between July 2019 and July 2024. Patients were randomly allocated to FJ and non-FJ groups in a 1:1 ratio. The primary endpoints were procedure-related complications (POPF, delayed gastric emptying (DGE), post-pancreatectomy haemorrhage, bile leak, Clavien-Dindo grade ≥ 3), hospital stay, additional costs and 30-day mortality in patients with clinically relevant POPF. Of the 100 patients, 50 underwent routine FJ ",,,auto_pubmed,scipeerai_collector_v1,pmid:40105276
+SPB-0097,10.1177/13860291241291411,Effects of resistance training on microcirculation of bone tissue and bone turnover markers in postmenopausal women with osteopenia or osteoporosis: A systematic review.,"Sangtarash Fatemeh, Shadmehr Azadeh, Choobsaz Haniyeh, Fereydounnia Sara, Sadeghi Alireza, et al.",2025,Clinical hemorheology and microcirculation,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"After menopause, there is an imbalance between bone formation and resorption activity, which could lead to postmenopausal osteopenia or osteoporosis. Resistance training (RT) can induce mechanical stress on bone which is necessary for bone remodeling and angiogenic-osteogenic response. This systematic review aims to assess the effects of RT on bone microcirculation and bone turnover markers (BTMs) in postmenopausal women with osteopenia or osteoporosis. We conducted a comprehensive search for related studies published up to April 2023 to identify eligible articles. Out of 316 articles identified, the full texts of 69 articles were screened. There is not any study which consider the effect of resistance exercises on bone microcirculation in PMOP women, but four articles aseess the effect of RT on BTMs and were reviewed. The quality of the articles was assessed by using the Physiotherapy Evidence Database (PEDro) scale. In one study, after 6- and 12 -months RT, bone formation and bone re",,,auto_pubmed,scipeerai_collector_v1,pmid:39973439
+SPB-0098,10.1186/s12879-025-11497-y,Non-tuberculous mycobacterial infections among pulmonary tuberculosis suspected and confirmed patients in Ethiopia - A systematic review and meta analyses.,"Daka Deresse, Tessema Belay, Mutshembele Awelani, Alelign Amir, Birhan Wubet, et al.",2025,BMC infectious diseases,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Nontuberculous mycobacteria (NTM) are environmental pathogens found in soil, water, and various environments, causing chronic pulmonary infections. They are resistant to chlorine and extreme temperatures but not typically transmissible. NTM infections are often misdiagnosed as tuberculosis (TB), especially in Ethiopia, where data on prevalence is scarce. This research aims to analyze NTM isolation from pulmonary samples and other specimens used in pulmonary tuberculosis (PTB) diagnosis among patients suspected or confirmed as PTB cases in Ethiopia. This study systematically reviews and synthesizes published studies that report NTM isolation from sputum and other clinical samples in Ethiopia to estimate the overall prevalence of NTM isolation, identify the common species, and analyze regional variations in their occurrence. This systematic review and meta-analysis aimed to determine NTM prevalence in infected individuals in Ethiopia. Using PubMed, Scopus, Web of Science, Google Scholar,",,,auto_pubmed,scipeerai_collector_v1,pmid:40877844
+SPB-0099,10.1111/jsap.13880,"Factors associated with the development of gastrointestinal adverse events in dogs with multicentric lymphoma treated with CHOP or CEOP-based protocols: a multi-institutional, retrospective study.","Treggiari E, Catania E, Valenti P, Boyd K, Finotello R",2025,The Journal of small animal practice,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Canine multicentric lymphoma is treated with multidrug protocols that include an anthracycline, namely doxorubicin, epirubicin or mitoxantrone. Both epirubicin and doxorubicin are known to cause gastrointestinal adverse events; however, very few reports have focused on comparing adverse events of the two drugs. The aim of this study was to analyse the frequency and severity of gastrointestinal adverse events in dogs with a diagnosis of lymphoma treated with a multi-agent protocol including either doxorubicin or epirubicin. The medical databases of four institutions were retrospectively searched for dogs with a confirmed diagnosis of lymphoma that had received a CHOP or a CEOP protocol. Analysed variables included breed, sex, age, body weight, clinical stage, substage, immunophenotype, use of prednisolone, initial dose of anthracycline and remission status following the first administration of anthracycline. Dogs with detected gastrointestinal involvement, suspected gastrointestinal lym",,,auto_pubmed,scipeerai_collector_v1,pmid:40320245
+SPB-0100,10.2147/DDDT.S514091,"Effects of Prophylactic Infusion of Equivalent Doses of Norepinephrine and Phenylephrine in Preventing Spinal Anesthesia-Induced Hypotension During Cesarean Delivery on Fetal and Maternal Outcomes: A Dual-Center, Non-Inferiority Controlled Trial.","Mao Junqin, Lin Kang, Liu Xiang, Liu Jie, Liang Gang, et al.",2025,"Drug design, development and therapy",pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Numerous studies have compared the effects of norepinephrine and phenylephrine on maternal and neonatal outcomes during cesarean delivery. However, the infusion rates are often based on clinical experience, resulting in non-equivalent doses. We aimed to compare the effects of norepinephrine and phenylephrine at equivalent doses on fetal and maternal outcomes, and assess their efficacy at the 90% effective dose (ED<sub>90</sub>). A total of 100 parturients scheduled for cesarean delivery were randomly allocated to receive either 0.10 μg/kg/min norepinephrine (Group NE) or 0.60 μg/kg/min phenylephrine (Group PE) to prevent spinal anesthesia-induced hypotension. The primary endpoint was neonatal umbilical arterial (UA) pH and the incidence of maternal hypotension, while secondary endpoints included hemodynamic changes within the first 15 minutes, maternal adverse events, and additional neonatal measures. Of the 95 subjects who completed the study, the UA pH in Group NE (7.296 ± 0.041) was",,,auto_pubmed,scipeerai_collector_v1,pmid:40557054
+SPB-0101,10.1007/s00345-025-05741-y,Mini-PCNL (percutaneous nephrolithotomy) vs. FURSL (flexible ureteroscopy and laser lithotripsy): a head-to-head comparison in treating calyceal diverticulum stones: a prospective randomized study.,"Shello Haitham Abdalla, Gabril Mahmoud, Elhendawy Abdelaziz",2025,World journal of urology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"To compare the efficacy and safety of mini-percutaneous nephrolithotomy versus flexible ureteroscopy with laser lithotripsy in the management of calyceal diverticulum stones. This prospective study was performed on 91 patients across four medical centers in Saudi Arabia from January 2020 to June 2024 with confirmed calyceal diverticulum stones. Seven patients who did not meet the inclusion criteria were excluded. A total of 78 patients with CD stones were randomly divided into two groups: Group A (n = 39) for fURSL and Group B (n = 39) for min-PCNL. Patient demographics, stone complexity and size, operative parameters, and postoperative results were analyzed. Primary and secondary results included stone-free rates (SFRs), operative time, hospital stay, complication rates, and recovery time. Statistical analysis was conducted using SPSS software. Both groups exhibited comparable baseline characteristics and surgical feasibility. The mini-PCNL group demonstrated a higher SFR (84.62% vs. ",,,auto_pubmed,scipeerai_collector_v1,pmid:40522357
+SPB-0102,10.1007/s12029-025-01238-4,Statin use and Pancreatic Cancer: A Meta-analysis of its Association with Incidence in the General Population and Survival in Patients.,"Paul Jibon Kumar, Azmal Mahir, Talukder Omar Faruk, Ghosh Ajit",2025,Journal of gastrointestinal cancer,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Statins have been appearing as a potential anti-cancer agent in numerous studies. The study aimed to unravel the impact of statins in pancreatic cancer in terms of reducing the occurrence (morbidity) and improving survival (mortality). A comprehensive search of databases was carried out to collect the eligible studies up to July 2024. This meta-analysis evaluates two distinct questions: (1) whether statin use reduces the incidence of pancreatic ductal adenocarcinoma (PDAC) in the general population, and (2) whether statins improve survival among patients diagnosed with PDAC. In total, 39 studies were included in the meta-analysis, comprising 15 case-control studies, 20 cohort studies, three randomized controlled trials, and one non-randomized controlled trial. A generic inverse variance weighted random-effects model was applied to calculate the pooled risk ratio and 95% confidence intervals. Subgroup analyses were performed based on the availability of relevant information. In the tota",,,auto_pubmed,scipeerai_collector_v1,pmid:40379858
+SPB-0103,10.1016/j.heliyon.2024.e40931,"Advancements in synthesis, immobilization, characterization, and multifaceted applications of silver nanoparticles: A comprehensive review.","Uddin Rabbi Md Belal, Haque Sadia, Bedoura Sultana",2024,Heliyon,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Silver nanoparticles (AgNPs) have attracted significant interest in recent years owing to their unique physicochemical properties, including antimicrobial reduction capabilities, photocatalytic activity, self-cleaning features, superhydrophobicity, and electrical conductivity. Their characteristics render them highly advantageous for various textile, electronics, food and agriculture, water treatment, and biomedical applications. This detailed analysis explores the recent benefits and drawbacks of various synthesis methods, immobilization techniques, and characterization of AgNPs while emphasizing novel strategies that improve their functionality across different substrates. A comprehensive analysis is conducted on various synthesis methods, including physical, chemical, and biological approaches. Additionally, immobilization techniques such as in-situ synthesis, pad-dry-cure, and printing on diverse substrates are thoroughly examined for their role in enhancing the functionality of te",,,auto_pubmed,scipeerai_collector_v1,pmid:39759340
+SPB-0104,10.1371/journal.pone.0317112,RETRACTED: The association between maternal tobacco smoking during pregnancy and the risk of attention-deficit/hyperactivity disorder (ADHD) in offspring: A systematic review and meta-analysis.,"Mohammadian Mahdi, Khachatryan Lusine G, Vadiyan Filipp V, Maleki Mostafa, Fatahian Fatemeh, et al.",2025,PloS one,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Maternal tobacco smoking during pregnancy is a significant public health concern with potential long-lasting effects on child development. ADHD, a neurodevelopmental disorder characterized by inattention, hyperactivity, and impulsivity, may be influenced by prenatal nicotine exposure. This systematic review and meta-analysis examine the association between maternal tobacco smoking during pregnancy and the risk of ADHD in offspring. Following PRISMA guidelines, we searched databases including PubMed, Web of Science, Cochrane Central, Embase, Scopus, CINAHL, LILACS, SciELO, Allied and Complementary Medicine Database (AMED), ERIC, CNKI, HTA Database, Dialnet, EBSCO, LENS, and Google Scholar for studies up to November 1, 2024. We included peer-reviewed studies reporting quantitative effect size estimates for the association between maternal tobacco smoking and ADHD. Study quality was assessed using the Newcastle-Ottawa Scale (NOS). We identified 2,981 articles and included 55 studies (4,01",,,auto_pubmed,scipeerai_collector_v1,pmid:39919144
+SPB-0105,10.1016/j.ejogrb.2025.114023,Prenatal diagnosis and molecular cytogenetic analyses of a rare 17q12 microdeletion and 17q11.2 microduplication family with normal phenotype.,"Tian Weihua, Xia Qi, He Xian, Leng Pei",2025,"European journal of obstetrics, gynecology, and reproductive biology",pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Copy number variants (CNVs) are an important source of normal and pathogenic genome variations. Microdeletion of chromosome 17q12 results in structural or functional abnormalities in the kidney and urethra, type 5 diabetes (MODY5), and neurodevelopmental or neuropsychiatric disorders. Microduplication of 17q11.2 are less well-characterized but have been associated with variable clinical presentations, including autism spectrum disorder (ASD), developmental delay, and mild dysmorphic features. In this research, a 29-year-old woman (gravida 1, para 0) underwent amniocentesis at 22 weeks' gestation following the detection of bilateral hyperechogenic fetal kidneys on prenatal ultrasound. Notably, her husband has a medical history of congenital ichthyosis type 10, a genetic condition that warranted further genetic investigation. Copy number variation sequencing (CNV-seq) from this family revealed a 1.46-Mb microdeletion on chromosome 17q12 and a 640-kb microduplication on chromosome 17q11.2",,,auto_pubmed,scipeerai_collector_v1,pmid:40315683
+SPB-0106,10.1177/13860291251324086,Possibility of modern ultrasound imaging of portal venous system.,"Juan Cheng, Yijie Qiu, Wen-Ping Wang, Fleischmann Johannes, Greiner Barbara, et al.",2025,Clinical hemorheology and microcirculation,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"During the past few years, there have been a number of new technical developments in the field of high-performance ultrasound diagnostics, which should help us to better assess dynamic vascular changes with ultrasound. BMUS enables us to get important anatomical variants with regard to the portal venous vessels and the hepatic veins. With color-coded duplex sonography (CCDS), and power Doppler (PD), examiners can carry out a comprehensive hemodynamic assessment of the portal venous. However, low flow settings in the vein have always been a particular challenge for CCDS, since the examiner requires special experience and artefacts often occur. In this review article, we reviewed the technical basics and diagnostic possibilities of new digital vascular ultrasound methods, 3D flow methods and contrast enhanced ultrasound (CEUS) in the assessment of portal venous flow changes.",,,auto_pubmed,scipeerai_collector_v1,pmid:40452393
+SPB-0107,10.1097/MD.0000000000041172,Small cell lung cancer progressing into fatal ascending motor and sensory polyneuropathy despite dramatic response to chemotherapy: A case report.,"Naqvi Syed Mohammad, Hashim Hashim Talib, Naqvi Syed Yaseen, Alhatemi Ahmed Qasim Mohammed, Sulaiman Fatimah Abdullah, et al.",2025,Medicine,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Paraneoplastic syndromes occur in 10% to 20% of all malignancies, with paraneoplastic neurological syndromes in less than 1% of all malignancies. In small cell lung cancer (SCLC), paraneoplastic manifestations are more common, affecting up to 5% of cases. Common manifestations include syndrome of inappropriate antidiuretic hormone secretion, Cushing's syndrome due to adrenocorticotropic hormone secretion, paraneoplastic cerebellar degeneration, and Lambert-Eaton myasthenic syndrome. Paraneoplastic acute motor and sensory polyneuropathy is an exceptionally rare but severe complication, necessitating timely diagnosis and management. A 55-year-old male with an 80 pack-year history of smoking presents to the hospital with a 3-week history of fevers, productive cough, dyspnoea, and wheeze. He had no significant comorbidities. Extensive radiological investigations revealed a large mass at the right hilum compressing on the right lower bronchus with metastatic adrenal deposits. Biochemical in",,,auto_pubmed,scipeerai_collector_v1,pmid:40184144
+SPB-0108,10.17235/reed.2025.11004/2024,WITHDRAWN: Esophageal lichen planus treated with upadacitinib.,"Gutiérrez Fernández Ana Isabel, Munitiz Ruiz Vicente, Ruiz de Angulo Martín David, Ortiz Escandell Ángeles, Conesa Plá Ana, et al.",2025,Revista espanola de enfermedades digestivas,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Esophageal lichen planus (ELP) is a rare chronic inflammatory condition with delayed diagnosis that can present with dysphagia. It has been scarcely studied in the literature, and clinical management guidelines are lacking. Stenosis and neoplastic transformation are among its most feared complications. We present the fifth reported case of ELP to be successfully treated with Upadacitinib.",,,auto_pubmed,scipeerai_collector_v1,pmid:39831617
+SPB-0109,10.1021/acssynbio.4c00758,Novel Reprogramming of Polyketide Synthase for Valerolactam Production.,"Zong Jikai, Xiao Kaixing, Wang Dan, Kang Yaqi, Peng Zhiyao, et al.",2025,ACS synthetic biology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"δ-Valerolactam (VL), as an organic compound, is an important precursor chemical for nylon and has a wide range of applications in organic synthesis, pharmaceutical synthesis, polymer materials, and other fields. This study introduces a novel biosynthetic method for producing VL in the engineered strain Escherichia coli BL21 through the reprogramming of polyketide synthases (PKS). Initially, an in vitro multienzyme system was constructed to verify the reliability of the VL synthesis pathway. Subsequently, an optimized biosynthetic pathway was established in E. coli, converting l-aspartate to VL with a yield of 3.66 mg/L in a 250 mL shake flask. Various engineering strategies were then implemented to enhance VL production, including substrate-enzyme affinity modification and multidimensional substrate optimization. These methods resulted in a 3.7-fold increase in VL yield, reaching 13.5 mg/L in shake flask cultures. Further scale-up in a 5 L fed-batch fermenter achieved a VL concentratio",,,auto_pubmed,scipeerai_collector_v1,pmid:39985475
+SPB-0110,10.1159/000549272,Cardiac Arrhythmias Associated with Brain Tumors: A Systematic Review.,"Hullon Darshan, Farhan Eesha, Hussain Fatima, Ahad Abiya, Akhavan Mandana, et al.",2025,Cardiology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Brain tumors may disrupt cardiac autonomic regulation, leading to arrhythmias that complicate patient management. This review aims to synthesize evidence on the relationship between brain tumor characteristics, treatments, and cardiac arrhythmias. A systematic literature search was performed with independent screening and data extraction by two reviewers. Due to heterogeneity in study designs, tumor types, and arrhythmia outcomes, quantitative meta-analysis was not feasible; results were synthesized qualitatively. Supratentorial tumors, especially in limbic and insular regions, were frequently associated with atrial arrhythmias and ECG abnormalities. High-grade tumors showed diverse arrhythmias, including bradycardia and ventricular events, often linked to tumor progression or seizures. Surgical resection improved arrhythmias but posed perioperative risks, notably with right insular involvement. Chemotherapy effects were variable; radiation-induced arrhythmias were infrequent and dose-",,,auto_pubmed,scipeerai_collector_v1,pmid:41166511
+SPB-0111,10.3390/brainsci15091022,RETRACTED: Idea Density and Grammatical Complexity as Neurocognitive Markers.,"Iacono Diego, Feltis Gloria C",2025,Brain sciences,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Language, a uniquely human cognitive faculty, is fundamentally characterized by its capacity for complex thoughts and structured expressions. This review examines two critical measures of linguistic performance: idea density (ID) and grammatical complexity (GC). ID quantifies the richness of information conveyed per unit of language, reflecting semantic efficiency and conceptual processing. GC, conversely, measures the structural sophistication of syntax, indicative of hierarchical organization and rule-based operations. We explore the neurobiological underpinnings of these measures, identifying key brain regions and white matter pathways involved in their generation and comprehension. This includes linking ID to a distributed network of semantic hubs, like the anterior temporal lobe and temporoparietal junction, and GC to a fronto-striatal procedural network encompassing Broca's area and the basal ganglia. Moreover, a central theme is the integration of Chomsky's theories of Universal",,,auto_pubmed,scipeerai_collector_v1,pmid:41008382
+SPB-0112,10.1016/j.ijbiomac.2025.145377,Transferrin-guided liposomal nanocarriers: A strategy for targeted cancer treatment.,"Saeed Mohd, Altamash Mohd, Almoyad Mohammad Ali Abdullah, Wahab Shadma, Gupta Garima, et al.",2025,International journal of biological macromolecules,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Cancer, characterized by uncontrolled cell proliferation and aberrant vascularization, remains a major challenge in clinical therapeutics. While chemotherapy is a cornerstone of cancer treatment, its effectiveness is often limited by systemic toxicity and lack of tissue specificity, which constrain the achievable therapeutic doses. When compared to traditional formulations, targeted drug delivery systems employing nanoparticles have demonstrated up to ten times greater bioavailability and three to five times higher drug accumulation in tumor tissues. Nanoparticles (NPs) offer versatile and customizable platforms that improve the solubility, permeability, and bioavailability of therapeutic agents. In addition, NPs exhibit favorable pharmacokinetic properties, enable sustained and controlled drug release, and allow selective targeting of specific cells, tissues, or organs-collectively enhancing the therapeutic efficacy of conventional drugs. Also, by lowering systemic toxicity, nanocarri",,,auto_pubmed,scipeerai_collector_v1,pmid:40545105
+SPB-0113,10.1111/dom.70201,Effects of GLP-1 receptor agonists on cognitive function in patients with type 2 diabetes: A systematic review and meta-analysis based on randomized controlled trials.,"Wan Suxin, Yan He, Sun Qiu-Yan, Zhu Jia-Quan, Wang Hui-Hong, et al.",2026,"Diabetes, obesity & metabolism",pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Patients with type 2 diabetes mellitus (T2DM) have a significantly increased risk of cognitive impairment, and the protective effects of traditional hypoglycaemic drugs on cognitive function remain unclear. This study systematically evaluated the neuroprotective effects of GLP-1 receptor agonists (GLP-1RAs) based on randomized controlled trial (RCT) evidence, aiming to provide key evidence-based insights for optimizing diabetes management strategies. A comprehensive literature search was conducted across PubMed, Embase, Cochrane Library, Web of Science, CNKI, Wanfang, and ClinicalTrials.gov databases to identify studies investigating the impact of GLP-1RAs on cognitive function in T2DM patients, with the search timeframe extending up to July 2025. The analysis focused on RCTs comparing the effects of GLP-1RAs versus placebo (or conventional therapy) on neurocognitive function in T2DM patients. Based on the inclusion criteria, 18 RCTs involving 11 114 participants were included in the p",,,auto_pubmed,scipeerai_collector_v1,pmid:41104525
+SPB-0114,10.1007/s11250-025-04376-w,Factors affecting Nile crocodile (Crocodylus niloticus) leather quality: a systematic review.,"Khosa Ndzalo, Nemutandani Khetho Ratshilumela",2025,Tropical animal health and production,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Leather from the Nile crocodile (Crocodylus niloticus) is highly valued in global markets due to its durability, distinct texture, and aesthetic appeal. Despite its economic importance, the crocodile industry faces substantial challenges in maintaining the leather quality due to a variety of influencing factors. This study systematically reviews the literature that investigated the genetic, environmental, and management factors that influence the leather quality of Nile crocodiles. A comprehensive search on Google Scholar, ResearchGate, PubMed, and ScienceDirect databases yielded twenty-four studies published between 1960 and 2023. The analysis shows that genetic diversity and selective breeding programs play an important role in improving skin quality by promoting desirable traits and disease resistance. Environmental factors such as water quality, temperature, and habitat conditions have a substantial impact on skin health, with poor water quality and extreme temperatures contributin",,,auto_pubmed,scipeerai_collector_v1,pmid:40100477
+SPB-0115,10.1093/postmj/qgaf048,"Volrustomig/Rilvegostomig related ""triple M""-myasthenia gravis and overlap syndrome.","Cooksley Tim, Keh Ryan Y S, Weaver Jamie M J",2025,Postgraduate medical journal,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,,,,auto_pubmed,scipeerai_collector_v1,pmid:40179144
+SPB-0116,10.1016/j.ctarc.2025.100873,WITHDRAWN: Association between Prostatic Calculi and Prostate Cancer.,"Fan Yaqin, Luan Yang, Zhu Liangyong, Huang Tianbao, Ding Xuefei, et al.",2025,Cancer treatment and research communications,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/policies/article-withdrawal.,,,auto_pubmed,scipeerai_collector_v1,pmid:40102170
+SPB-0117,10.1016/S1470-2045(25)00408-5,De-escalation of adjuvant radiotherapy in HPV-associated oropharyngeal cancer.,Petkar Imran,2025,The Lancet. Oncology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,,,,auto_pubmed,scipeerai_collector_v1,pmid:40907508
+SPB-0118,10.3390/biology13120998,RETRACTED: IAV Antagonizes Host Innate Immunity by Weakening the LncRNA-LRIR2-Mediated Antiviral Functions.,"Chen Na, Zhang Baoge",2024,Biology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"A growing number of studies have shown that long non-coding RNAs (lncRNAs) are implicated in many biological processes, including the regulation of innate immunity and IAV replication. In addition, IAV has been found to be able to hijack lncRNAs and thus antagonize host innate immunity. Nonetheless, whether IAV can antagonize host innate immunity by weakening the antiviral functions mediated by lncRNAs is unknown. In this study, we found that LncRNA-ENST00000491430 regulates IAV replication and named it LRIR2. Interestingly, we found that the expression of LRIR2 was suppressed during IAV infection. Importantly, LRIR2 overexpression inhibited IAV replication, suggesting that LRIR2 plays an antiviral role during IAV infection. Mechanistically, we demonstrated that LRIR2 inhibits the transcription and replication of the IAV genome. In addition, the antiviral function of LRIR2 is mainly dependent on the stem-loop structures of 1-118 nt and 575-683 nt. Taken together, IAV could antagonize h",,,auto_pubmed,scipeerai_collector_v1,pmid:39765665
+SPB-0119,10.1016/j.heliyon.2025.e41813,Hydroxyapatite-based coatings on Mg and Ti-based implants: A detailed examination of various coating methodologies.,"Rafiei M, Eivaz Mohammadloo H, Khorasani M, Kargaran F, Khonakdar H A",2025,Heliyon,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Metallic implants have been considered as promising alternatives to traditional implants due to their biocompatibility and favorable biodegradability properties. However, one of the major challenges in using these implants is the relatively fast degradation rate of metal alloys in the body's electrolyte environment, which can lead to early loss of performance and the release of undesirable degradation products. Applying appropriate coatings with suitable performance on the surface of metal implants can be an effective solution to control the rate of deterioration and increase their stability in the body environment. In this comprehensive study, various methods of coating metal implants with calcium phosphate or hydroxyapatite structures, including sol-gel, chemical deposition (such as hydrothermal deposition), and thermal spraying (such as plasma spray) methods have been fully investigated. The benefits and drawbacks of each of these techniques in relation to the properties of the resu",,,auto_pubmed,scipeerai_collector_v1,pmid:39897808
+SPB-0120,10.1007/s11306-025-02229-z,"Harnessing NMR technology for enhancing field crop improvement: applications, challenges, and future perspectives.","Gautam Vedant, Garg Vibhootee, Meena Nitesh, Kumari Sunidhi, Patel Shubham, et al.",2025,Metabolomics : Official journal of the Metabolomic Society,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Nuclear Magnetic Resonance (NMR) spectroscopy has emerged as a transformative technology in agricultural research, offering powerful analytical capabilities for field crop improvement. With global challenges such as food security and climate change intensifying, there is an urgent need for innovative methodologies to enhance our understanding of plant health, metabolic pathways, and crop-environment interactions. NMR's ability to provide nondestructive, real-time analysis of plant metabolites and soil chemistry positions it as a critical tool for addressing these pressing concerns. This review aims to elucidate the potential of NMR spectroscopy in advancing field crop improvement by highlighting its applications, challenges, and future perspectives in agricultural methodologies. The focus is on the evolution and application of NMR in agricultural research, particularly in metabolomics, phenotyping, and quality assessment. A comprehensive literature review was conducted to analyze recen",,,auto_pubmed,scipeerai_collector_v1,pmid:39979661
+SPB-0121,10.1097/TA.0000000000004520,"""Pager's trauma"" as a new and destructive type of blast injuries [RETRACTED].","Rasouli Hamid Reza, Khoshmohabat Hadi, Ahmadpour Fathollah",2024,The journal of trauma and acute care surgery,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,,,,auto_pubmed,scipeerai_collector_v1,pmid:39722177
+SPB-0122,10.1093/bib/bbaf149,FGeneBERT: function-driven pre-trained gene language model for metagenomics.,"Duan Chenrui, Zang Zelin, Xu Yongjie, He Hang, Li Siyuan, et al.",2025,Briefings in bioinformatics,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Metagenomic data, comprising mixed multi-species genomes, are prevalent in diverse environments like oceans and soils, significantly impacting human health and ecological functions. However, current research relies on K-mer, which limits the capture of structurally and functionally relevant gene contexts. Moreover, these approaches struggle with encoding biologically meaningful genes and fail to address the one-to-many and many-to-one relationships inherent in metagenomic data. To overcome these challenges, we introduce FGeneBERT, a novel metagenomic pre-trained model that employs a protein-based gene representation as a context-aware and structure-relevant tokenizer. FGeneBERT incorporates masked gene modeling to enhance the understanding of inter-gene contextual relationships and triplet enhanced metagenomic contrastive learning to elucidate gene sequence-function relationships. Pre-trained on over 100 million metagenomic sequences, FGeneBERT demonstrates superior performance on meta",,,auto_pubmed,scipeerai_collector_v1,pmid:40211978
+SPB-0123,10.1177/13860291241306566,Rapid screening system to identify unspecific peroxygenase activity.,"Schramm Marina, Carrillo Avilés Carlos Renato, Kalmbach Johannes, Schmidtke Kai-Uwe, Kiebist Jan, et al.",2025,Clinical hemorheology and microcirculation,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Unspecific peroxygenases (UPO, EC 1.11.2.1) are a valuable tool for the biocatalytic synthesis of specialty chemicals such as pharmaceutical metabolites. However, the search for new UPOs that are recombinantly expressible can be tedious and dependent on expensive equipment, especially when a large number of clones has to be examined. In this study, we present a simple agar plate-based method for the screening of active, secreted UPOs heterologously expressed in Saccharomyces cerevisiae. This allows a real high-throughput of several thousand clones at once. The approach was successfully tested with a small gene library comprising putative UPO genes and resulted in the identification of two clones producing short UPOs from the filamentous fungi Dendrothele bispora (DbiUPO) and Aspergillus niger (AniUPO). Both UPOs were partly purified and characterized with respect to their catalytic properties. With differing efficiencies and product specificities, they catalyzed the formation of human ",,,auto_pubmed,scipeerai_collector_v1,pmid:40289415
+SPB-0124,10.1111/xen.70021,Evaluation of Complement-Dependent Cytotoxicity Assays for Gene-Edited Pig-to-Human Xenotransplantation.,"Feng Hao, Zhang Man, Xia Qiangbing, Du Jiaxiang, Li Tao, et al.",2025,Xenotransplantation,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Gene-edited pigs for xenotransplantation usually contain one or more transgenes encoding human complement regulatory proteins (CRPs). Because of species differences, human CRP(s) expressed in gene-edited pigs may have difficulty inhibiting the activation of exogenous rabbit complement added to a complement-dependent cytotoxicity (CDC) assay. The use of human complement instead of rabbit complement in CDC experiments may more accurately reflect the actual regulatory activity of human CRP(s). Peripheral blood mononuclear cells (PBMCs) were obtained from one GTKO pig and two GTKO/hCD55 pigs with a high or low level of hCD55 expression. After incubation of heat-inactivated normal human sera (HINHS) with porcine PBMCs, CDC levels were measured after the addition of commercial rabbit complement or human complement. In addition, a modified one-step CDC method was established using pooled normal human sera (NHS) without the addition of an exogenous complement. There was no significant differen",,,auto_pubmed,scipeerai_collector_v1,pmid:39960350
+SPB-0125,10.7759/cureus.76664,Congenital Hydronephrosis Due to Pyeloureteral Atresia: A Case Report.,"Alowainati Zainab H, Salman Zainab H, Alhamad Hibah A, Alsudairy Njood",2024,Cureus,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Intussusception is a leading cause of acute intestinal obstruction in infants, typically presenting with a classic triad of intermittent abdominal pain, vomiting, and currant jelly stools. However, atypical presentations can lead to diagnostic delays, increasing the risk of complications. This report describes a seven-month-old male with an unusual presentation of lethargy and irritability, without overt gastrointestinal symptoms. Initial clinical examination, including abdominal palpation and laboratory tests, was inconclusive. However, abdominal ultrasonography revealed a subtle ""target sign,"" confirming intussusception despite the absence of hallmark signs. The patient underwent successful hydrostatic reduction under fluoroscopic guidance, with no pathological lead points identified. The case highlights the importance of maintaining clinical suspicion for intussusception in atypical presentations, emphasizing the critical role of early imaging in achieving timely diagnosis and favor",,,auto_pubmed,scipeerai_collector_v1,pmid:39886710
+SPB-0126,10.7759/cureus.75264,Exploring Occupational Health Challenges in Pathology: A Cross-Sectional Survey of Indian Pathologists.,"Kanungo Rahul, Sharma Anjali, Pagi Sajal, Sachar Kanika",2024,Cureus,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Introduction Occupational health hazards are a significant concern for pathologists due to their unique work environment. These professionals face risks from prolonged microscope use, exposure to chemicals such as formalin, and handling sharp instruments, leading to issues such as musculoskeletal disorders and needlestick injuries. Addressing these hazards is crucial for their well-being and the overall efficiency of medical diagnostics. Implementing effective safety measures and increasing awareness can create a safer and healthier workplace for pathologists. Objective This study primarily aimed to assess the prevalence of occupational health hazards among Indian pathologists. It further assessed the knowledge and attitudes of pathologists toward safety practices in pathology. Specifically, it explored the research questions: What are the levels of awareness and adherence to safe practices among pathologists? What common factors contribute to reluctance in following these practices, p",,,auto_pubmed,scipeerai_collector_v1,pmid:39776702
+SPB-0127,10.7759/cureus.86035,The Impact of Intraoperative Imaging on Outcomes in Combined Neurosurgical and Reconstructive Procedures: A Systematic Review.,"Alozai Muhammad Ilyas, Amgad Yehia Elassra Omar, Alkhazendar Aliaa H, Ibrahim Ahmed S, Sattar Gatta Abdul, et al.",2025,Cureus,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"This systematic review evaluates the impact of intraoperative imaging on surgical outcomes in combined neurosurgical and reconstructive procedures. A comprehensive literature search was conducted across four databases, including PubMed, Scopus, Web of Science, and the Cochrane Central Register of Controlled Trials (CENTRAL), focusing on clinical trials published between 2019 and 2024. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, six studies that met stringent eligibility criteria were selected, including randomized controlled trials (RCTs) and prospective cohort studies involving imaging modalities such as intraoperative MRI (iMRI), intraoperative ultrasound (iUS), fluoroscopy, neuronavigation, and machine vision-based systems. Data were extracted on sample size, intervention type, control group characteristics, and primary surgical outcomes, including extent of resection, complication rates, and functional recovery. Qualitative synt",,,auto_pubmed,scipeerai_collector_v1,pmid:40666576
+SPB-0128,10.1371/journal.pone.0324738,An eel-like robot based on a dielectric elastomer.,Zhang Chenghong,2025,PloS one,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Eels have attracted significant research interest because of their long-distance migration and high-endurance cruising behavior. An underwater eel-like robot design inspired by these creatures has the potential for high efficiency, strong maneuverability and high stability. The propulsive biomimetic eel-like robot has the lowest energy consumption per unit distance, and its flexible body is conducive to movement and operation in narrow spaces; this is expected to become the research and development direction for underwater biomimetic robots. Dielectric elastomers (DEs) are smart, soft materials that exhibit significant deformation under an electric field and have the characteristics of large strain, fast response, light mass, etc. Applying DEs in the effort to develop bionic robots affords a unique advantage. This study introduces an eel-inspired swimming robot. First, a cylindrical dynamic model of a DE is established. Second, considering the eel as the bionic object, a tube actuator ",,,auto_pubmed,scipeerai_collector_v1,pmid:40632709
+SPB-0129,10.1038/s41598-025-04072-7,Enhancing blockchain transaction classification with ensemble learning approaches.,"Panigrahi Amrutanshu, Pati Abhilash, Sahu Bibhuprasad, Paul Rourab, Nayak Ajit Kumar, et al.",2025,Scientific reports,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Since the emergence of Blockchain as Bitcoin, its development has progressed rapidly and attracted the attention of various researchers in academia and industry. Blockchain technology is becoming an increasingly secure and effective way to share information in various industries, including finance, supply chain management (SCM), and the Internet of Things (IoT). The increase in the number of Blockchain users demands malicious and non-malicious transactions to maintain the trust in Blockchain. This research aims to develop a machine learning (ML) based model for classifying blockchain transactions into risky or non-risky ones. The model comprises four feature selection approaches, including Correlation-based Feature Selection (CFS), Recursive Feature Elimination (RFE), Random Forest (RF), and Information Gain (IG). Then, two ensemble feature selection methods, known as rank averaging and rank aggregation, are applied to combine the features selected from the initial feature selection me",,,auto_pubmed,scipeerai_collector_v1,pmid:40595930
+SPB-0130,10.1371/journal.pone.0325367,RETRACTED: ICN intrusion detection method based on GA-CNN.,"Zhang Jianpeng, Wang Xueli",2025,PloS one,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"The current industrial control system network is susceptible to data theft attacks such as SQL injection in practical applications, resulting in data loss or leakage of enterprise secrets. To solve the network intrusion problem faced by industrial control systems in the current global communication security environment, a network intrusion detection method based on genetic algorithm and improved convolutional neural network is proposed. Genetic algorithm is utilized to solve and optimize the data, one-dimensional multi-scale convolutional neural network is combined with gated recurrent unit to improve the network intrusion detection model, and finally the detection and defense of industrial control network intrusion is completed. GA is used to optimize the feature selection process to identify the key feature subsets that have the greatest impact on model performance. One-dimensional multi-scale convolutional neural network captures multi-scale features in network traffic data through ",,,auto_pubmed,scipeerai_collector_v1,pmid:40460379
+SPB-0131,10.1038/s41598-025-19006-6,RETRACTED ARTICLE: An attention-based multi-residual and BiLSTM architecture for early diagnosis of autism spectrum disorder.,"Alkhawaldeh Rami S, AlShaqsi Jamil, Al-Ahmad Bilal, Alkhawaldeh Samar M, Drogham Osama",2025,Scientific reports,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"The Editor has retracted and removed this publication. Concerns were raised regarding the use of images of minors from a non-curated dataset. The dataset is reported to contain images of children with ASD. However, the images appear to have been collected from the internet without any documented clinical history or confirmation of an actual ASD diagnosis. Additionally, there is no documented ethical oversight, or consent of the children included in the dataset or their parents and legal guardians. In light of these ethical concerns and the reliance on unverifiable data, the Editor and Publisher no longer have confidence in the reliability of this article. Author Rami S. Alkhawaldeh has stated that the authors disagree with this retraction.",,,auto_pubmed,scipeerai_collector_v1,pmid:41023066
+SPB-0132,10.1016/j.heliyon.2025.e41654,A mechanistic overview on green assisted formulation of nanocomposites and their multifunctional role in biomedical applications.,"Mahnoor, Malik Khafsa, Kazmi Abeer, Sultana Tahira, Raja Naveed Iqbal, et al.",2025,Heliyon,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"The importance of nanocomposites constantly attains attention because of their unique properties all across the fields especially in medical perspectives. The study of green-synthesized nanocomposites has grown to be extremely fascinating in the field of research. Nanocomposites are more promising than mono-metallic nanoparticles because they exhibit synergistic effects. This review encapsulates the current development in the formulation of plant-mediated nanocomposites by using several plant species and the impact of secondary metabolites on their biocompatible functioning. Phyto-synthesis produces diverse nanomaterials with biocompatibility, environment-friendliness, and in vivo actions, characterized by varying sizes, shapes, and biochemical nature. This process is advantageous to conventional physical and chemical procedures. New studies have been conducted to determine the biomedical efficacy of nanocomposites against various diseases. Unfortunately, there has been inadequate inve",,,auto_pubmed,scipeerai_collector_v1,pmid:39916856
+SPB-0133,10.1016/j.jtumed.2025.07.012,Antimicrobial efficacy of methylene blue-functionalized graphene oxide-mediated photodynamic therapy against <i>Enterococcus faecalis</i> in root canal disinfection.,"Jouhar Rizwan, Halim Mohamad S, Quadri Sayed A, Ahmed Muhammad A, Shah Faheem",2025,Journal of Taibah University Medical Sciences,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"This study assessed the antimicrobial efficacy of photodynamic therapy (PDT) using functionalized graphene oxide with methylene blue (MB/rGO) to achieve root canal disinfection against Enterococcus faecalis. In this in vitro study, E. faecalis biofilms were developed on 105 single-rooted teeth after decoronation over 21 days. Bacterial viability was assessed with colony forming unit (CFU) analysis. Six experimental groups with equal numbers of samples (n = 15) were treated with 5 % NaOCl (groups 1 and 2), MB-based PDT (groups 3 and 4), or MB/rGO-based PDT (groups 5 and 6). Sonic activation (groups 2, 4, and 6) was performed at 6000 cpm for 2 min, whereas laser activation (groups 3-6) was performed with a 650 nm, 200 mW laser for 2 min. Post-treatment CFU/mL counts and bacterial load decreases were recorded. A substantial decrease in bacterial load (p < 0.001) was observed across all experimental groups. The highest decrease (99.99 %) was observed in group 6 (modified PDT with MB/rGO), ",,,auto_pubmed,scipeerai_collector_v1,pmid:40861276
+SPB-0134,10.1002/cbdv.202500613,"RETRACTED: The South Asian Acalypha Species: A Comprehensive Review on Traditional Uses, Phytochemistry and Pharmacological Aspect.","Labu Zubair Khalid, Karim Samira, Arifuzzaman Sarder, Motalab Salsabil Binte, Alzahrani Khalid J, et al.",2025,Chemistry & biodiversity,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"The genus Acalypha (family Euphorbiaceae) has a longstanding role in traditional medicine across South Asia, used to treat conditions such as diabetes, asthma, gastrointestinal disorders, and skin ailments. Its widespread ethnomedicinal use suggests promising pharmacological applications. This review comprehensively examines the origin, habitat, taxonomy, conventional uses, phytochemistry, and pharmacological properties of Acalypha species (AS). Data were compiled from more than 100 peer-reviewed studies retrieved from multiple scientific databases (e.g., PubMed, PubChem, Scopus, ScienceDirect, and others). Phytochemical structures were generated using Chemaxon Marvin Sketch, and data were evaluated to assess chemical diversity and biological activity. Key species such as Acalypha hispida, Acalypha paniculata, Acalypha fruticosa, Acalypha wilkesiana, and Acalypha indica are prevalent in tropical and subtropical regions. These plants contain various bioactive compounds, including alkalo",,,auto_pubmed,scipeerai_collector_v1,pmid:40616829
+SPB-0135,10.1021/acs.langmuir.5c01641,Recent Advances and Strategic Advantages in the Construction and Biomedical Applications of Functional Protein Scaffold-Based Nanozymes: A Review.,"Le Guannan, Ma Xiaoyu, Muhmood Azhar",2025,Langmuir : the ACS journal of surfaces and colloids,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Nanozymes are a class of nanomaterials with enzyme-like activities that have garnered increasing attention due to their potential applications in biomedicine. However, designing nanozymes with the desired properties remains challenging due to issues such as potential biotoxicity and nonselective harmful effects, which limits their biomedical applications. Nowadays, natural or genetically engineered protein scaffolds have emerged as a promising platform for nanozyme design, owing to their unique structural properties, biomineralization capabilities, self-assembly features, and high biocompatibility. Herein, we focus on the main types of protein scaffolds, including natural proteins, recombinant protein, genetic engineering modification recombinant proteins, and biological matrix protein frameworks, used to design of nanozymes, and the classical methods of designing protein scaffold-based nanozymes. We also explore the advantages of genetically engineered proteins in the versatile design",,,auto_pubmed,scipeerai_collector_v1,pmid:40633053
+SPB-0136,10.1016/j.bbrc.2025.152800,Carboxyl ester lipase truncation mutant unveils lipotoxicity induced pancreatic β-cell demise.,"Lin Jianli, Lin Yi, Li Jinxin, Liu Qinwen, Lin Xiafang, et al.",2025,Biochemical and biophysical research communications,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Mutations in carboxyl ester lipase (CEL) cause maturity-onset diabetes of the young type 8 (MODY8), yet the mechanism linking exocrine CEL deficiency to β-cell failure remains unclear. Here, we demonstrate that a truncating CEL mutant (MUT-CEL, c.538 + 16C > T) is aberrantly internalized by β-cells, where it forms cytotoxic aggregates that resist degradation. These aggregates induce endoplasmic reticulum stress, trigger a sustained unfolded protein response, and drive β-cells into a senescent state characterized by cell cycle arrest and loss of identity markers. Crucially, we identify cyclin-dependent kinase 4 (CDK4) dysfunction as a central mediator of this lipotoxicity induced senescence. Restoration of CDK4 activity rescues β-cell proliferation and function in vitro and in vivo, revealing a targetable pathway to mitigate β-cell demise in MODY8.",,,auto_pubmed,scipeerai_collector_v1,pmid:41167005
+SPB-0137,10.7759/cureus.86034,Multidisciplinary Surgical Management of Concurrent Traumatic Brain and Abdominal Injuries: A Systematic Review of Integrated Care Approaches and Clinical Outcomes.,"Oriko David O, H J Alkhazendar Jarallah, Alkhazendar Aliaa H, Taha Mawada, Sattar Gatta Dr Abdul, et al.",2025,Cureus,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"This systematic review explores the impact of multidisciplinary surgical management on clinical outcomes in patients with concurrent traumatic brain and abdominal injuries, two of the most life-threatening forms of polytrauma. By analyzing evidence from recent observational studies, expert consensus, and systematic reviews, this study highlights the clinical relevance of coordinated multidisciplinary care. The available evidence, though limited, suggests that early and integrated surgical intervention may improve survival rates, reduce ICU admissions and length of stay, and enhance neurological recovery. This review provides a focused evaluation of the existing literature, emphasizing the clinical relevance of structured, team-based approaches in managing the complex pathophysiology and treatment priorities of patients with dual traumatic insults. The study also identifies current gaps in evidence and calls for further prospective research to establish standardized protocols and improv",,,auto_pubmed,scipeerai_collector_v1,pmid:40666570
+SPB-0138,10.7759/cureus.86252,"Multidisciplinary Approaches to Limb Salvage in Traumatic Extremity Injuries From Emergency Triage to Definitive Vascular, Orthopedic, and Reconstructive Surgery: A Systematic Review.","Issa Youssouf Nabila, Khan Huba Ali, Ahmed Osman Mohamed Asma, Bahaa Aboelsebaa Othman Mohamed, Ismail Mahmoud Hassan Fadul, et al.",2025,Cureus,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"This systematic review explores the impact of multidisciplinary team (MDT) approaches in the management of complex limb injuries, comparing limb salvage and amputation outcomes across diverse trauma settings. Drawing from six recent studies involving both acute and chronic extremity trauma, the findings highlight consistent benefits of coordinated care involving orthopedic, vascular, and plastic surgery specialties. These include reduced flap loss, faster time to definitive fixation, improved functional recovery, and enhanced decision-making regarding salvage versus amputation. While functional and psychological outcomes following salvage and amputation were often comparable, early MDT involvement improved wound healing and lowered short-term mortality rates in select patient groups. Variability in outcomes was influenced by institutional resources, timing of intervention, and patient comorbidities. Scoring systems such as the Mangled Extremity Severity Score (MESS) and the Mangled Ext",,,auto_pubmed,scipeerai_collector_v1,pmid:40688983
+SPB-0139,10.2147/PRBM.S510544,Evaluating the Efficacy of Music-Based Therapy in Children and Adolescents with Physical and Mental Health Challenges: A Systematic Review.,Yiwei Xu,2025,Psychology research and behavior management,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Music therapy (MT) has gained recognition as an effective intervention for addressing both psychological and physiological challenges among children and adolescents. Research consistently highlights its therapeutic potential in managing various health conditions. This systematic review consolidates evidence from 14 studies involving 2,789 participants, assessing the efficacy of music-based interventions in enhancing mental and physical health outcomes. Adhering to the PRISMA framework, the study employed strict selection criteria to maintain methodological rigor and relevance. Findings indicate that a majority of the studies reported moderate to high effect sizes, with notable improvements in emotional stability, stress management, and motor recovery. Interventions involving active engagement-such as instrumental play, singing, and structured rhythmic activities-demonstrated greater effectiveness compared to passive exposure to music. A critical gap identified in the literature is the ",,,auto_pubmed,scipeerai_collector_v1,pmid:40421183
+SPB-0140,10.1016/j.heliyon.2024.e40635,Analyzing the influence of financial technology and environmental taxation on energy transformation in BRI nations.,"Zou Yefan, Ma Ninger",2024,Heliyon,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"This research examined the management, financial technology, and environmental taxation elements impacting energy transformation in Belt and Road Initiative (BRI) countries concerning foreign direct investment (FDI). The study aims to analyze data from 2014 to 2022, encompassing a balanced group of 148 BRI member nations-72 from minimal and lower-middle-class countries and 78 from significant and middle-income industrialized nations. Utilizing the two-step systems generalized method of moments (GMM) framework and verifying with the two-stage least squares (2SLS) approach, the study identified critical drivers and barriers to energy transformation in these countries. The findings indicate that effective management practices, advanced financial technologies, and appropriate environmental taxation policies significantly influence energy transformation and FDI inflows. Additionally, the research reviewed the impact of cruise tourism on human health and environmental ecosystems, highlightin",,,auto_pubmed,scipeerai_collector_v1,pmid:39759329
+SPB-0141,10.1371/journal.pone.0315105,An immunoinformatics and extensive molecular dynamics study to develop a polyvalent multi-epitope vaccine against cryptococcosis.,"Sami Md Razwan Sardar, Rani Nurul Amin, Elahi Mohammad Mahfuz Enam, Hossain Mohammad Sajjad, Al Mueid Minhaz Abdullah, et al.",2024,PloS one,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Cryptococcosis is a lethal mycosis instigated by the pathogenic species Cryptococcus neoformans and Cryptococcus gattii, primarily affects the lungs, manifesting as pneumonia, and the brain, where it presents as meningitis. Mortality rate could reach 100% if infections remain untreated in cryptococcal meningitis. Treatment options for cryptococcosis are limited and and there are no licensed vaccines clinically available to treat or prevent cryptococcosis. Our study utilizes an integrated bioinformatics approaches to develop a polyvalent multiepitope subunit vaccine focusing on the key virulent proteins Heat shock transcription factor and Chaperone DnaK of both C. neoformans and C. gatti. Then in silico analysis was done to predict highly antigenic epitopes by assessing antigenicity, transmembrane topology screening, allergenecity, toxicity, and molecular docking approaches. Following this analysis, we designed two vaccine constructs integrating a compatible adjuvant and suitable linker",,,auto_pubmed,scipeerai_collector_v1,pmid:39739919
+SPB-0142,10.3389/fnins.2024.1491343,Annao Pingchong decoction attenuates oxidative stress and neuronal apoptosis following intracerebral hemorrhage via RAGE-NOX2/4 axis.,"Wang Xu, Lin Xiaoyuan, Chen Zilin, Long Hongping, Zhou Xuqing, et al.",2024,Frontiers in neuroscience,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Intracerebral hemorrhage (ICH) is a severe condition associated with high mortality and disability rates. Oxidative stress plays a critical role in the development of secondary brain injury (SBI) following ICH. Previous research has demonstrated that Annao Pingchong decoction (ANPCD) treatment for ICH has antioxidant effects, but the exact mechanism is not yet fully understood. This study aimed to investigate the neuroprotective effects of ANPCD on oxidative stress and neuronal apoptosis after ICH by targeting the receptor for advanced glycation end products (RAGE)-NADPH oxidase (NOX) 2/4 signaling axis. The research involved the creation of rat ICH models, the mNSS assay to assess neurological function, Nissl staining to evaluate neuronal damage, and biochemical assays to measure oxidative and antioxidant levels. The expression of RAGE-NOX2/4 axis proteins was analyzed using western blotting and immunofluorescence, while neuronal apoptosis was assessed with TUNEL staining. Furthermore",,,auto_pubmed,scipeerai_collector_v1,pmid:39737434
+SPB-0143,10.1097/EDE.0000000000001897,"Erratum: Effect Modification in Settings with ""Truncation by Death"".",Unknown,2025,"Epidemiology (Cambridge, Mass.)",pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,,,,auto_pubmed,scipeerai_collector_v1,pmid:40657751
+SPB-0144,10.1007/s00134-025-08130-6,Beyond the numbers: do nomograms capture the complexity of RRT dosing?,"Aphale Parth, Dokania Shashank, Shekhar Himanshu",2025,Intensive care medicine,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,,,,auto_pubmed,scipeerai_collector_v1,pmid:40986017
+SPB-0145,10.1364/OL.564000,Unconventional optical response of time-domain Fibonacci quasicrystals.,"Naweed Ahmer, Akhtar Muhammad Shaban",2025,Optics letters,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"We investigate the propagation and localization of light waves in the time-domain Fibonacci quasicrystals (FQCs), which are constructed following the Fibonacci sequence generation rule. We demonstrate the transmission of amplified optical waves through FQCs. The reflectivity of FQCs displays unusual behavior since the reflection band may repeatedly flip and amplify for the alternating sequences. Thus, amplified light wave transport can result in both outputs of FQCs, leading to similar transmission and reflection spectra, although the amplification for the two outputs differs. It is found that the localization of light is only possible if the reflection band does not flip. In addition, spectral modifications resulting from the index modulation of a specific sequence-based FQC may contrast sharply with the spectral response of a conventional FQC. The findings of this computational study aid in enhancing the capabilities of the time-domain FQCs in a range of applications, such as high-tr",,,auto_pubmed,scipeerai_collector_v1,pmid:40751981
+SPB-0146,10.2147/PRBM.S508557,The Effect of Age Stereotype in Elderly Adults with the Mediation Role of Self-Esteem and Sense of Coherence.,"Rasool Abida, Abdullaeva Barno, Nazarov Akmal, Kozokboeva Dilfuzakhon, Abdullaev Rustam, et al.",2025,Psychology research and behavior management,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"This systematic review article considers the intertwinement of sense of coherence, self-esteem, and age stereotype among the heterogeneous aging population. Aging is multifaceted and complex, and older persons are a mosaic of values, experience, and psychological responses to society's perception of their age. Underpinning this portrayal is the understanding that aging is not unidimensional but rather a complex aggregate of processes, challenges, and psychological processes. The first half describes the interdependence between age stereotypes and age discrimination and calls for the struggle against ageism at the social, institutional, and individual levels. The second half explores the influence of negative aging stereotypes on the self-concept of the elderly in Poland. It is necessary to investigate these processes to develop interventions and support systems suitable for the specific needs of the aging population. The third part deals with the complex cluster of self-concepts of sel",,,auto_pubmed,scipeerai_collector_v1,pmid:40548173
+SPB-0147,10.1016/j.jtho.2025.05.013,TEMPORARY REMOVAL: Tobacco News Update-From the IASLC Tobacco Control Committee.,Unknown,2025,Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"The publisher regrets that this article has been temporarily removed. A replacement will appear as soon as possible in which the reason for the removal of the article will be specified, or the article will be reinstated. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/policies-and-standards/article-withdrawal.",,,auto_pubmed,scipeerai_collector_v1,pmid:40445152
+SPB-0148,10.1016/j.sopen.2024.12.008,Surgical procedures and techniques in robot-assisted retrograde para-aortic lymphadenectomy.,"Wang Xinyou, Na Jing, Li Ya, Han Shichao, Wang Jun",2025,Surgery open science,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,,,,auto_pubmed,scipeerai_collector_v1,pmid:39990722
+SPB-0149,10.1016/S0140-6736(25)00489-1,Taiwan's national health care on the brink of systemic collapse.,"Li Jing-Xing, Hsu Shu-Bai",2025,"Lancet (London, England)",pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,,,,auto_pubmed,scipeerai_collector_v1,pmid:40287228
+SPB-0150,10.1016/j.ijregi.2025.100692,Non-tuberculous mycobacterial infections among patients with suspected or confirmed pulmonary tuberculosis in Ethiopia: A systematic review and meta-analysis.,"Daka Deresse, Tessema Belay, Mutshembele Awelani, Alelign Amir, Birhan Wubet, et al.",2025,IJID regions,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"This study reviews and analyzes non-tuberculous mycobacteria (NTM) isolation from Ethiopian sputum samples, estimating prevalence, identifying common species, and analyzing regional and temporal variations. This systematic review and meta-analysis aimed to determine NTM prevalence among diseased individuals in Ethiopia. Using PubMed, Scopus, Web of Science, Google Scholar, and African Journals Online, we conducted a comprehensive literature search. Data extraction and quality assessment were conducted using the Newcastle-Ottawa scale. Meta-analysis was performed using STATA-18 software with a random-effects model and included subgroup analysis. The protocol of this study was registered with PROSPERO (CRD420251000131). In this review, a total of 5415 participants were involved, and 53.8% were patients with suspected tuberculosis (TB), 37.6% were patients with pulmonary TB, 4.0% were patients with multidrug-resistant TB, and 4.6% were HIV-positive patients. The NTM prevalence was 3.8%, s",,,auto_pubmed,scipeerai_collector_v1,pmid:40727033
+SPB-0151,10.1016/j.jenvman.2025.125840,Hybrid electric vehicles and sustainable development: A mixed-method analysis.,"Kautish Pradeep, Grebinevych Oksana, Roubaud David, Uddin S M Fatah, Siddiqui Aaliyah",2025,Journal of environmental management,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"The present study's objective is to determine the explanations (in favour and against) behind the attitude and intention of Generation-Z customers to adopt hybrid electric vehicles (HEVs). The research has adopted a mixed-methods design to explore and recognise the context-defined explanations (in favour and against) for HEV adoption and the moderating influence of sustainability consciousness grounded on behavioural reasoning theory. Initially, a qualitative approach was employed, followed by a survey-based quantitative approach. The hypothesised model was verified with 562 respondents employing partial-least square structural equation modelling. The results support those reasons for and against HEV adoption, which are predicted by values (terminal and instrumental) that significantly determine the attitudes and intentions of Generation-Z consumers. Both 'reasons for' (e.g., perceived marketplace influence, incentive policy, financial benefits, and ascribed responsibility) and 'reason",,,auto_pubmed,scipeerai_collector_v1,pmid:40381305
+SPB-0152,10.3389/fmed.2025.1630824,Application of artificial intelligence-assisted Traditional Chinese medicine formula granules in bone and joint degenerative diseases in the field of holistic health.,"Zhang Xian-Quan, Wei Xing-De, Gu Zhuo-Xu, Zhou Guang-Hui, Huang Chu-Jia, et al.",2025,Frontiers in medicine,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"As global aging intensifies, the incidence of degenerative bone and joint diseases such as osteoarthritis bone aging and osteoporosis continues to rise. Traditional treatment methods face bottlenecks in long-term management, including drug side effects and low patient compliance. Traditional Chinese medicine (TCM) formula granules, which utilize plant-based natural products, show excellent clinical efficacy in managing these conditions. With the development of technology, artificial intelligence (AI) technology has enhanced the clinical efficacy of TCM formula granules through multiple approaches such as intelligent syndrome differentiation and formula optimization, drug efficacy prediction and mechanism analysis, as well as patient management and therapeutic effect monitoring, providing a new approach for the prevention and treatment of complex degenerative diseases. This paper systematically reviews the core advantages of TCM formula granules and their suitability for orthopedic dise",,,auto_pubmed,scipeerai_collector_v1,pmid:40687718
+SPB-0153,10.3389/fpsyg.2025.1675490,"Bridging the gaps in eating disorder care: a systematic and comparative review of guidelines for prevention, early intervention, and service delivery.","Monaco Francesco, Vignapiano Annarita, Landi Stefania, Panarello Ernesta, Pullano Ilaria, et al.",2025,Frontiers in psychology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Eating Disorders (EDs) pose a significant public health challenge due to their psychiatric and somatic complexity, high chronicity, and elevated mortality rates. Despite the growing body of evidence and international awareness, the quality and consistency of clinical guidelines remain variable. This systematic review aimed to evaluate and compare existing clinical guidelines and position papers addressing prevention, early intervention, and multidisciplinary treatment for EDs. A systematic search of PubMed and American Psychological Association (APA) PsycINFO was conducted for documents published between January 2015 and March 2025. Eighteen documents were included, encompassing formal guidelines, consensus statements, and national policies. Key domains were extracted and synthesized across documents. Quality was assessed using the Appraisal of Guidelines for Research and Evaluation II (AGREE II) and the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) tools. ",,,auto_pubmed,scipeerai_collector_v1,pmid:41132608
+SPB-0154,10.1007/s10143-025-03398-0,Sarcopenia as a predictor of poor functional outcome of cervical spine surgery: a systematic review and meta-analysis.,"Tayal Anish, Wahi Satyam, Afsar Aiman Perween, Pahwa Bhavya, Garg Kanwaljeet",2025,Neurosurgical review,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Sarcopenia is a progressive loss of muscle mass. This study aims to determine the association of pre-operative sarcopenia with the outcome of cervical spine surgery. Pubmed, Ovid, Embase, and Web of Sciences databases were searched until September 2023 to include articles regarding the prognostic role of preoperative sarcopenia in cervical spine surgery patients. The Quality In Prognosis Studies (QUIPS) tool was used to assess the risk of bias. Meta-analyses Of Observational Studies in Epidemiology (MOOSE) and Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines were followed. The vote-counting model was used for the qualitative appraisal of the studies. Statistical analysis was performed with a significant p < 0.05 using SPSS software (version 23). Of the 1,134 articles revealed from the search, 15 studies with 1463 patients were included. A significant difference between patients with and without sarcopenia was not found for the occurrence of loss of",,,auto_pubmed,scipeerai_collector_v1,pmid:39976777
+SPB-0155,10.1159/000549037,Is Methylene Blue a Reliable Substitute in Sentinel Lymph Node Biopsy? A Systematic Review Across Oncologic Sites.,"Raj Saurabh, Mahaldar Rudrakshi, Memon Shahrukh",2025,European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Sentinel lymph node biopsy (SLNB) is a pivotal technique for evaluating regional lymphatic spread in breast, melanoma, and gynecologic malignancies. It minimizes surgical morbidity by avoiding complete lymphadenectomy in early-stage disease. The standard dual-tracer approach-combining a radiocolloid such as technetium-99m with a blue dye like patent blue or isosulfan blue-has high sensitivity but is not universally accessible. Radiocolloids require nuclear medicine facilities' licensing and pose logistical burdens, while patent blue may provoke allergic reactions, including anaphylaxis. These limitations are particularly pronounced in low- and middle-income countries (LMICs), where access and affordability are ongoing challenges. Methylene blue (MB), a low-cost, widely available dye, has gained traction as an alternative tracer, offering a safer and more feasible option for SLNB in resource-limited settings. This systematic review evaluates the diagnostic accuracy, detection reliabilit",,,auto_pubmed,scipeerai_collector_v1,pmid:41199536
+SPB-0156,10.1038/s41598-025-06229-w,Multimodal deep learning for cephalometric landmark detection and treatment prediction.,"Gao Fei, Tang Yulong",2025,Scientific reports,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"In orthodontics and maxillofacial surgery, accurate cephalometric analysis and treatment outcome prediction are critical for clinical decision-making. Traditional approaches rely on manual landmark identification, which is time-consuming and subject to inter-observer variability, while existing automated methods typically utilize single imaging modalities with limited accuracy. This paper presents DeepFuse, a novel multi-modal deep learning framework that integrates information from lateral cephalograms, CBCT volumes, and digital dental models to simultaneously perform landmark detection and treatment outcome prediction. The framework employs modality-specific encoders, an attention-guided fusion mechanism, and dual-task decoders to leverage complementary information across imaging techniques. Extensive experiments on three clinical datasets demonstrate that DeepFuse achieves a mean radial error of 1.21 mm for landmark detection, representing a 13% improvement over state-of-the-art met",,,auto_pubmed,scipeerai_collector_v1,pmid:40651957
+SPB-0157,10.1371/journal.pone.0320979,RETRACTED: N-Beats architecture for explainable forecasting of multi-dimensional poultry data.,"Kaur Baljinder, Rakhra Manik, Sharma Nonita, Prashar Deepak, Mrsic Leo, et al.",2025,PloS one,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"The agricultural economy heavily relies on poultry production, making accurate forecasting of poultry data crucial for optimizing revenue, streamlining resource utilization, and maximizing productivity. This research introduces a novel application of the N-BEATS architecture for multi-dimensional poultry data forecasting with enhanced interpretability through an integrated Explainable AI (XAI) framework. Leveraging its advanced capabilities in time series modeling, N-BEATS is applied to predict multiple facets of poultry disease diagnostics using a multivariate dataset comprising key environmental parameters. The methodology empowers decision-making in poultry farm management by providing transparent and interpretable forecasts. Experimental results demonstrate that N-BEATS outperforms conventional deep learning models, including LSTM, GRU, RNN, and CNN, across various error metrics, achieving MAE of 0.172, RMSE of 0.313, MSLE of 0.042, R-squared of 0.034, and RMSLE of 0.204. The posit",,,auto_pubmed,scipeerai_collector_v1,pmid:40273069
+SPB-0158,10.1038/s41598-025-85291-w,An assessment of physiological and health responses in Catla catla fingerlings after polystyrene microplastic exposure.,"Rashid Eram, Hussain Syed Makhdoom, Ali Shafaqat, Kucharczyk Dariusz, Nowosad Joanna, et al.",2025,Scientific reports,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Microplastics (MPs) form when plastic debris is released into the aquatic environment, where they decompose and have deleterious effects on aquatic life. This study aimed to examine the harmful impacts of polystyrene MPs (PS-MPs) on the growth, carcass composition, hematology, digestibility, histopathology, and mineral analysis of Catla catla (11.09 ± 0.09 g/fish). Six experimental diets were prepared using canola meal (CM) as the base, each containing varying levels of PS-MPs: a control diet without MPs, and diets with 0.5%, 1%, 1.5%, 2%, and 2.5% PS-MPs. For ninety days, three groups of 15 fingerlings each were fed the test diets at a rate of 5% of their live, wet body weight. The growth rate and feed intake of C. catla fish showed a significant decline after the exposure to the diet containing 2.5% PS-MPs. Dietary inclusion of 2.5% PS-MPs resulted in reduced weight gain (g) and increased FCR. Mineral content and nutritional digestibility declined as PS-MP levels rose. PS-MPs led to ",,,auto_pubmed,scipeerai_collector_v1,pmid:39820509
+SPB-0159,10.1016/j.ijcard.2025.133309,RETRACTED: Myocardial contraction fraction in HFpEF: Prognostic value and unaddressed confounders.,"Zhang Shiyu, Zhang Yanhong, Weng Jiajun",2025,International journal of cardiology,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"This article has been retracted: please see Elsevier policy on Article Correction, Retraction and Removal (https://www.elsevier.com/about/policies-and-standards/article-withdrawal). This Letter to the Editor, 'Myocardial contraction fraction in HFpEF: Prognostic value and unaddressed confounders', has been retracted at the request of the Editor-in-Chief and the Authors. The authors have notified the journal that the suggestion on the effects of disorders in serum potassium levels and unadjusted confounding factors such as patients with cardiomyopathy requires substantial clarification. The authors' exploration of MCF was primarily preliminary, and has inadvertently misrepresented the authors' discussion. Due to the significance of the reanalysis and its potential implications for the study's interpretation, the authors and the editorial board have agreed that the most responsible course of action is to retract the article.",,,auto_pubmed,scipeerai_collector_v1,pmid:40280336
+SPB-0160,10.1016/j.jcyt.2023.09.004,"WITHDRAWN: Expression of concern: ""Combined 4-1BB and ICOS co-stimulation improves anti-tumor efficacy and persistence of dual anti-CD19/CD20 chimeric antigen receptor T cells"" [Cytotherapy, Volume 23, Issue 8, 2021, 715-723].",Unknown,2024,Cytotherapy,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/policies/article-withdrawal.,,,auto_pubmed,scipeerai_collector_v1,pmid:39985542
+SPB-0161,10.1121/10.0039380,Quasi-zero stiffness resonators: Breaking low-frequency sound absorption limits.,"Shen Chao, Tang Tianquan, Liu Yu",2025,The Journal of the Acoustical Society of America,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Traditional acoustic resonators often face a fundamental trade-off between achieving low-frequency resonance and maintaining a broad sound absorption bandwidth, particularly without increasing the physical cavity volume. This limitation poses significant challenges for compact and efficient low-frequency noise control. To address this issue, the present study introduces a novel sound absorption mechanism based on a two-hollow magnet quasi-zero stiffness (QZS) structure. By introducing magnetic negative stiffness, the system's effective stiffness is significantly reduced, enabling wider bandwidth at lower frequencies, thus surpassing the sound absorption performance limits of conventional Helmholtz resonators. The research integrates theoretical modeling, finite element simulation, and experimental validation using an impedance tube to thoroughly investigate the underlying absorption mechanisms. The QZS resonator allows the resonator's effective cavity height Heff to exceed the upper li",,,auto_pubmed,scipeerai_collector_v1,pmid:40991463
+SPB-0162,10.1021/acs.biomac.5c00266,Light-Triggered Cross-Linking of Linear Poly(ethylene glycol) Hydrogels for Enhanced Antibacterial Delivery.,"Liu Siyuan, Tian Yuan, Zhao Kaijie, Zhang Peiyu, Li Jia, et al.",2025,Biomacromolecules,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Due to the limited functional groups on poly(ethylene glycol) (PEG) terminals, hydrogels are usually prepared by PEG chains with multiple arms. It is challenging for the preparation of hydrogels using linear PEG. Herein, we report the light-triggered synthesis of hydrogels composed of linear PEG with bis-maleimide groups. In the presence of a photoinduced catalyst, the α-C-H bonds on the PEG chain are cleaved, allowing the maleimide groups to be incorporated into the main chain, forming a cross-linked structure. The cleavage of the unstable C-O bonds could result in degradation of hydrogels. The release of encapsulated tobramycin from degradable hydrogels shows better antibacterial properties compared to undegradable hydrogels, which results in highly effective antimicrobials at the wound site. This work presents a method for the preparation of degradable hydrogels using linear PEG as a component for biological applications.",,,auto_pubmed,scipeerai_collector_v1,pmid:40314935
+SPB-0163,10.1002/jca.70055,Beyond Donation: Rethinking Long-Term Support Systems for Hematopoietic Stem Cell Donors.,Sinha RishiRaj,2025,Journal of clinical apheresis,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,,,,auto_pubmed,scipeerai_collector_v1,pmid:40916372
+SPB-0164,10.7759/cureus.76355,Progressive Familial Intrahepatic Cholestasis Type 2 in an Infant: Diagnostic Challenges and Multidisciplinary Management.,"Ullah Najeeb, Anthony Somaan, Siddiqi Arzoo, Akram Nimra, Afghan Bismil",2024,Cureus,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Progressive familial intrahepatic cholestasis type 2 (PFIC2) is a rare genetic disorder characterized by severe intrahepatic cholestasis, which often manifests in infancy with progressive liver dysfunction. We present the case of a 3-month-old infant with a one-month history of jaundice, vomiting, and bloody stools, presenting a unique set of diagnostic challenges. Initial clinical and laboratory findings indicated significant liver dysfunction, prompting further imaging and genetic analysis. An abdominal ultrasound revealed hepatomegaly with a coarse liver texture, while a hepatobiliary iminodiacetic acid (HIDA) scan ruled out biliary atresia. Ultimately, genetic testing confirmed a mutation in the ABCB11 gene, diagnostic of PFIC2. Management included total parenteral nutrition to support growth, ursodeoxycholic acid to improve bile flow, and rifampicin to alleviate pruritus. Due to the severity of the disease, a liver transplant is planned as the definitive treatment following stabil",,,auto_pubmed,scipeerai_collector_v1,pmid:39867052
+SPB-0165,10.1177/23779608251349403,Satisfaction of Nurses Regarding Workplace Facilities in a Tertiary Hospital.,"Shipa Mst Fatiha Eyasmin, Akhtar Khursheda, Sanda Samina Akter, Bose Lita, Ara Beauty",2025,SAGE open nursing,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Safe patient care is directly related to the quality of nurses' workplace facilities. Understanding their level of satisfaction can help identify areas for improvement and foster a supportive work environment, ultimately enhancing patient care outcomes. This study aims to investigate nurses' satisfaction with workplace facilities in a tertiary hospital. A descriptive cross-sectional study was conducted among 384 nurses working in a tertiary hospital. The study period was from January 1, 2023 to December 31, 2023. Convenient sampling techniques were used. Data was collected through pretested semi-structured questionnaires. The analysis of satisfaction level was categorized by 49 questions with a 5-point Likert scale and divided by percentile intervals. Cronbach's α shows the reliability of the data and the association between two categorical variables was done by the Chi-square test & Fisher exact test. p-value <.05 was considered as a level of significance. The study follows the STROBE",,,auto_pubmed,scipeerai_collector_v1,pmid:40496676
+SPB-0166,10.1016/j.vaccine.2025.127182,Effect of vaccine education intervention on vaccine uptake and vaccine knowledge among older adults: A systematic review with meta-analysis.,"Chan Yee Tang, Chair Sek Ying, Gao Rui Tong, Ng Ming Him, Lee Vivian Wing Yan",2025,Vaccine,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Educational intervention is one approach for providing vaccine knowledge and encouraging vaccine uptake. However, up till now, no systematic review reporting the effectiveness of vaccine educational intervention on vaccine uptake and/or knowledge enhancement for disease preventeable by the vaccine of interest, compared to conventional/standard or no intervention, for older adults aged 60 or above was found. Six databases, including PubMed, OVID, CINAHL, Web of Science, the Cochrane Library, and the British Nursing Index, were searched. Vaccine educational interventions in this study were interventions that encourage vaccine uptake and/or provide knowledge enhancement on diseases prevented by the vaccine. Conventional/standard or no intervention refers to vaccine educational intervention that existed prior to the commencement of the intervention or no vaccine educational intervention was performed at all. All included studies were randomized control trials. The appraisal was performed w",,,auto_pubmed,scipeerai_collector_v1,pmid:40318347
+SPB-0167,10.1007/s10143-025-03256-z,An early evaluation of robot-assisted and conventional techniques for posterior approach atlantoaxial displacement instrumentation - a systematic review and meta-analysis.,"Łajczak Paweł, Łajczak Anna, Buczkowski Stanisław, Jóźwik Kamil, Nowakowski Przemysław, et al.",2025,Neurosurgical review,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Atlantoaxial dislocation (AAD) is a serious condition in which the first two cervical vertebrae lose their anatomical position and stability. This may lead to neurological complications, including death. The treatment of AAD remains controversial, and posterior instrumentation with pedicle screw placement is one of the commonly used methods. The goal of this study is to evaluate the effectiveness of robot-assisted (RA) surgery compared to conventional techniques for posterior AAD instrumentation. Following Cochrane and PRISMA guidelines, five major databases were searched from inception to December 2024. Studies evaluating RA surgery compared to freehand (FH) or computer navigation methods were included. Outcomes included screw accuracy, surgery time, radiation exposure, and complications. A random-effects mean difference (MD) and odds ratio (OR) were used. After a comprehensive search, three studies were included. Two studies compared RA to FH, and one compared RA to navigation. Blood",,,auto_pubmed,scipeerai_collector_v1,pmid:39883207
+SPB-0168,10.1021/jacs.4c18303,Sorbent Mediated Electrocatalytic Reduction of Dilute CO<sub>2</sub> to Methane.,"Stanley Jared S, Pauker Hunter N, Kuker Erin, Dong Vy, Nielsen Robert J, et al.",2025,Journal of the American Chemical Society,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Efficient CO<sub>2</sub> utilization is a critical component of closing the anthropogenic carbon cycle. Most studies have focused on the use of pure streams of CO<sub>2</sub>. However, CO<sub>2</sub> is generally available only in dilute streams, which requires capture by sorbents followed by energy-intensive regeneration to release concentrated CO<sub>2</sub>. Direct utilization of sorbed-CO<sub>2</sub> avoids the costly regeneration step, and the sorbent-CO<sub>2</sub> interaction can kinetically activate CO<sub>2</sub> to tune its reactivity toward products that could otherwise be inaccessible with direct CO<sub>2</sub> reduction. We demonstrate that an N-heterocyclic carbene, 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene (DPIy), quantitatively reacts with CO<sub>2</sub> from dilute streams (0.04 and 10%) to form the sorbent-CO<sub>2</sub> substrate 1,3-bis(2,6-diisopropylphenyl)imidazolium-2-carboxylate (DPICx). Electrocatalyst iron tetraphenylporphyrin chloride (Fe(TPP)Cl) typi",,,auto_pubmed,scipeerai_collector_v1,pmid:40326475
+SPB-0169,10.3390/s25051339,RETRACTED: The Multi-Station Fusion-Based Radiation Source Localization Method Based on Spectrum Energy.,"He Guojin, Hao Yulong, Xie Yaocong",2025,"Sensors (Basel, Switzerland)",pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Today's highly complex and rapidly changing electromagnetic environment places higher demands on the precise localization of illegal radiation sources. In response to this, this paper innovatively proposes a multi-station fusion-based radiation source localization method, which leverages the frequency, field strength, bandwidth, and other characteristic information embedded in frequency band scanning data. The method thoroughly explores the energy characteristics of the detected radiation sources while closely integrating the objective laws of propagation attenuation in electromagnetic space. By employing an advanced, normalized power calculation technique, it successfully achieves high-precision localization of the radiation source. Through rigorous and thorough experimental validation, this method reduces localization errors by 25% and cuts the equivalent radiation power error by 30% compared to traditional localization methods. This achievement provides more reliable and accurate te",,,auto_pubmed,scipeerai_collector_v1,pmid:40096120
+SPB-0170,10.1371/journal.pone.0332120,Shaping environmental responsibility through virtual wilderness: The key role of aesthetic psychology.,"Miao Wenyu, Liu Yanyan",2025,PloS one,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,,,,auto_pubmed,scipeerai_collector_v1,pmid:41032508
+SPB-0171,10.1016/j.envres.2025.121178,MOF-derived Cu@Cu<sub>2</sub>O nanoclusters for photothermally enhanced Fenton-like catalytic degradation of dye pollutants.,"Cheng Ji, Guo Zuojia, Fan Wenxuan, Xu Pan, Lu Hanjing, et al.",2025,Environmental research,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"This paper presents a synthesis method for a novel octahedral Cu@Cu<sub>2</sub>O nanocluster (NAs), which is prepared by calcining Cu-BTC (metal-organic framework, 1,3,5-benzenetricarboxylate) in air, resulting in a porous carbon structure. The obtained Cu@Cu<sub>2</sub>O nanoclusters exhibit heterogeneous interfaces between Cu and Cu<sub>2</sub>O, significantly enhancing their Fenton-like catalysis and photothermal properties. Using SEM, TEM, XPS, and XRD techniques, the Cu@Cu<sub>2</sub>O NAs were comprehensively characterized. Upon near-infrared irradiation, these nanoclusters rapidly heat to 45 °C, generating reactive oxygen species (•OH) that effectively catalyze the degradation of Rhodamine B (RhB) dye. Moreover, cellular and animal experiments demonstrated that Cu@Cu<sub>2</sub>O NAs possess good biocompatibility and exhibit excellent biological safety. Overall, this study offers a promising and biocompatible material option for environmental remediation, integrating Fenton-like",,,auto_pubmed,scipeerai_collector_v1,pmid:39983962
+SPB-0172,10.1007/s11033-025-11263-y,Anti-tumor effects of GPC3 CAR-iNKT cells in murine models of hepatocellular carcinoma.,"Wang Zixuan, Zhang Guangji",2025,Molecular biology reports,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Glypican-3 (GPC3) has been identified as a compelling target for immunotherapy against hepatocellular carcinoma (HCC), owing to its selective expression on tumor cells. Chimeric antigen receptor invariant natural killer T (CAR-iNKT) cells have emerged as an innovative alternative to CAR-T cells, offering potential advantages for allogeneic applications in cellular therapy. In this study, we engineered GPC3-targeted CAR-iNKT cells and demonstrated their specific cytotoxic activity against GPC3-positive HCC cells in vitro. Using a murine HCC model, we further validated that GPC3 CAR-iNKT cells effectively suppressed tumor progression and enhanced survival outcomes. Pharmacokinetic studies showed favorable persistence of CAR-iNKT cells in vivo, with low off-target toxicity observed in critical organs. Collectively, these preclinical findings suggest that GPC3 CAR-iNKT cells may provide a safe and effective therapeutic option for HCC, warranting further investigation in clinical trials.",,,auto_pubmed,scipeerai_collector_v1,pmid:41264124
+SPB-0173,10.1093/bfgp/elaf009,Integration of single cell multiomics data by deep transfer hypergraph neural network.,"Kan Yulong, Zhang Zhongxiao, Wang Yingjie, Qi Yunjing, Chang Haoxin, et al.",2025,Briefings in functional genomics,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Multi-omics characterization of individual cells offers remarkable potential for analyzing the dynamics and relationships of gene regulatory states across millions of cells. How to integrate multimodal data is an open problem, existing integration methods struggle with accuracy and modality-specific biological variation retention. In this paper, we present scHyper (scalable, interpretable machine learning for single cell integration), a low-code and data-efficient deep transfer model designed for integrating paired and unpaired single-cell multimodal data. We benchmark scHyper against datasets from different multimodal data. ScHyper learns a low-dimensional representation and aligns the covariance matrices of the measured modalities, achieving high accuracy even with large scale atlas-level datasets with low memory and computational time across different cell lines, shedding light on regulatory relationships between different types of omics. Altogether, we show that scHyper is a versat",,,auto_pubmed,scipeerai_collector_v1,pmid:40884456
+SPB-0174,10.1016/j.jor.2025.10.002,Bibliometric analysis of mesenchymal stem cell-derived extracellular vesicles in the treatment of osteoarthritis.,"Fang Ying, Du Weibin, Zheng Wenyan, Chen Huanhuan, Gao Lidan, et al.",2026,Journal of orthopaedics,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"This study adopts bibliometric and visualization analysis to systematically investigate the research hotspots and emerging trends in the treatment of osteoarthritis with mesenchymal stem cell-derived extracellular vesicles, and conducts a review of related research. We conducted a search in the WoSCC (Web of Science Core Collection) for literature related to MSC-EVs in the treatment of osteoarthritis (OA) from January 1, 2013, to July 23, 2025, . Subsequently, we employed specialized software such as CiteSpace 6.1.R4, bibliometrix, and VOSviewer for scientometric analysis and keyword mining of the data. MSC-EVs treatment for OA is a research hotspot, and its intensity has been increasing in recent years. China, Italy, USA, and France are representative countries in this research field, with scholars such as De Girolamo, Laura making significant contributions to this area. IRCCS Istituto Ortopedico Galeazzi, National University of Singapore, Universite de Montpellier, and Shanghai Jiao ",,,auto_pubmed,scipeerai_collector_v1,pmid:41246172
+SPB-0175,10.2174/0115701638319534250314075737,WITHDRAWN: Role of Biomarkers for Diagnosis and Prediction in Type 1 Diabetes: An Overview.,"Janjire Omkar, Veeranjaneyulu Addepalli, Desai Shivani, Kale Govind",2025,Current drug discovery technologies,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Since the authors are not responding to the editor’s requests to fulfil the editorial requirement, therefore, the article has been withdrawn from the journal “Current Drug Discovery Technologies” Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused. The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php. It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submitting the article for publication the authors agree that the publishers have the legal right to take appropriate action against the authors, if plagiarism or fabricated information is discovered. By su",,,auto_pubmed,scipeerai_collector_v1,pmid:40176693
+SPB-0176,10.3390/metabo15020116,Potential Biomarkers of Fatal Hypothermia Revealed by UHPLC-MS Metabolomics in Mice.,"Cao Xin-Zhi, Wu Zhong-Wen, Ma Xing-Yu, Deng Wei-Liang, Chen Ding-Hao, et al.",2025,Metabolites,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"The postmortem diagnosis of fatal hypothermia presents a considerable challenge in forensic medicine. Metabolomics, a powerful tool reflecting comprehensive changes in endogenous metabolites, offers significant potential for exploring disease mechanisms and identifying diagnostic markers. In this study, we employed ultra-high-performance liquid chromatography-mass spectrometry (UHPLC-MS) to perform a non-targeted metabolomic analysis of liver, stomach, spleen, and musculus gastrocnemius tissues from mice subjected to fatal hypothermia. A substantial number of differential metabolites were identified in each tissue: 1601 in the liver, 420 in the stomach, 732 in the spleen, and 668 in the gastrocnemius muscle. The most significantly altered metabolites were as follows: magnoflorine (liver, upregulated, ranked first in fold-change), gibberellic acid (stomach, downregulated, ranked first in fold-change), nitrofurantoin (spleen, upregulated, ranked first in fold-change), and isoreserpin (ga",,,auto_pubmed,scipeerai_collector_v1,pmid:39997741
+SPB-0177,10.1016/j.saa.2025.126423,The effect of enantiomers of thalidomide on colon cells-Raman spectroscopy studies.,"Kopec Monika, Krzeminska Agnieszka, Surmacki Jakub, Krzyczmonik Paweł, Brożek-Płuska Beata",2025,"Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy",pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Enantiomers are molecules that have the same molecular formula but the atoms are linked differently. Differentiation between enantiomers is highly significant in scientific research, particularly in pharmaceuticals. This research demonstrates how conventional Raman spectroscopy and statistical methods can be applied to the analysis of enantiomers. The purpose of this study was to demonstrate that Raman spectroscopy reveals distinct spectral differences between the enantiomers of thalidomide. Density Functional Theory (DFT) computations support this observation and offer detailed insight into the underlying vibrational landscape. By decomposing the observed peaks into individual vibrational modes, they help clarify the specific contributions to the experimental spectra and provide a rationale for the intensity differences between R- and S-thalidomide. Furthermore, we studied the biochemical changes of Caco-2 human colon cells caused by incubation with enantiomers of thalidomide. In summ",,,auto_pubmed,scipeerai_collector_v1,pmid:40403464
+SPB-0178,10.1038/s41598-024-81487-8,Forecasting for electricity demand utilizing enhanced inception-V4 using improved Osprey optimization.,"Chen Suhua, Fang Xu, Khayatnezhad Majid",2024,Scientific reports,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"This research examines the impact of temperature, relative humidity, and wind speed on the electricity demand. It presents a unique method that combines an Enhanced Inception-V4 model with an Improved Osprey Optimizer to analyze weather-related factors. The combined model, which has been validated from 2003 to 2023, surpasses traditional forecasting techniques and significantly improves prediction accuracy. The Enhanced Inception-V4 model's ability to process data allows it to identify key factors that influence electricity demand patterns. Meanwhile, the Modified Osprey Optimizer fine-tunes the model's parameters, ensuring its adaptability to different weather scenarios. The study confirms the reliability of the OOI-Inception-V4 model in forecasting electricity demand and highlights the strong connection between weather conditions and energy usage, especially during extreme weather events. The projected increase in electricity demand from 2024 to 2030 emphasizes the importance of proa",,,auto_pubmed,scipeerai_collector_v1,pmid:39730630
+SPB-0179,10.1371/journal.pone.0336582,RETRACTED: Natural gas price prediction based on artificial intelligence models.,"Liu Xuhui, Tang Meiqi, Feng Yu, Fang Tianhui, Wang Zhuo, et al.",2025,PloS one,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"The natural gas supply crisis triggered by the Russia-Ukraine conflict has laid bare the energy market's extreme vulnerability in the face of geopolitical risk, highlighting the need for accurate multi-step gas price forecasting. However, most AI-based energy price studies have a gap: they focus on single-step prediction or homogeneous model comparisons, lacking analysis of performance degradation in multi-step dynamic frameworks. This study takes daily natural gas price data from the Henry Hub in the United States from 1997 to 2024 as the research object, constructs a multi-step prediction framework with a step size ranging from 1 to 4 days, and systematically compares the prediction performances of four artificial intelligence models: feedforward neural network, support vector machine, random forest, and long short-term memory network. The quantitative results show that, across all prediction cycles, the long short-term memory model has the lowest error rate. For example, in one-step",,,auto_pubmed,scipeerai_collector_v1,pmid:41325487
+SPB-0180,10.1186/s12917-025-04897-4,Physiological stage dependent hematobiochemical and echocardiographic changes in dromedary camels.,"Mousa Sabry, Ali Mohamed E, Tahoun Amin, El-Sayed Ahmed Adel, Marzok Mohamed, et al.",2025,BMC veterinary research,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"In livestock, identifying physiological and reproductive stages is crucial for informed decisions in nutrition, healthcare, and breeding management. This study aimed to evaluate hematobiochemical and Doppler echocardiographic changes in dromedary camels during three key stages: non pregnant, late pregnancy, and early lactation. Thirty healthy camels were monitored across three physiological stages. Blood samples were analyzed for complete blood count (CBC) and serum metabolic parameters, including Beta-hydroxy-butyric acid (BHBA) and non-esterified fatty acids (NEFA). Doppler echocardiography assessed cardiac morphology and function. Late pregnancy was associated with a significant (P < 0.05) increase in red blood cell (RBC) count, hemoglobin (Hb), and neutrophils, while packed cell volume (PCV), total white blood cell (WBC) count, and monocytes decreased. Serum glucose and cholesterol declined significantly (P < 0.05) in late pregnancy and early lactation, while Beta-hydroxy-butyric a",,,auto_pubmed,scipeerai_collector_v1,pmid:40619378
+SPB-0181,10.1371/journal.pone.0336241,RETRACTED: Interpretable machine learning framework for predicting Urban air quality.,"Latif Rana Muhammad Amir, Iqbal Tahir, Abdel Qader Ismaeel, Ikram Atif, Alsolai Hadeel, et al.",2025,PloS one,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Urban air pollution remains a critical challenge for public health and environmental sustainability. This study investigates the predictive capabilities of five machine learning (ML) models: Linear Regression (LR), Decision Tree (DT), Random Forest (RF), Extreme Gradient Boosting (XGBoost), and Support Vector Regression (SVR) for forecasting the Air Quality Index (AQI) using the widely adopted Air Quality dataset from the UCI ML Repository. Although collected in 2004-2005, the dataset continues to serve as a benchmark in recent literature and provides a reproducible testbed for methodological evaluation. After structured pre-processing, feature engineering, and chronological train-validation-test splitting, models were rigorously tuned and assessed using Root Mean Squared Error (RMSE), Mean Absolute Error (MAE), and coefficient of determination (R2), with 95% bootstrap confidence intervals and corrected resampled t-tests confirming statistical significance. Ensemble models achieved the",,,auto_pubmed,scipeerai_collector_v1,pmid:41201992
+SPB-0182,10.1038/s41598-025-00873-y,Optimizing credit card fraud detection with random forests and SMOTE.,"Sundaravadivel P, Isaac R Augustian, Elangovan D, KrishnaRaj D, Rahul V V Lokesh, et al.",2025,Scientific reports,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"In the financial world, Credit card fraud is a budding apprehension in the banking sector, necessitating the development of efficient detection methods to minimize financial losses. The usage of credit cards is experiencing a steady increase, thereby leading to a rise in the default rate that banks encounter. Although there has been much research investigating the efficacy of conventional Machine Learning (ML) models, there has been relatively less emphasis on Deep Learning (DL) techniques. In this article, a machine learning-based system to detect fraudulent transactions using a publicly available dataset of credit card transactions. The dataset, highly imbalanced with fraudulent transactions representing less than 0.2% of the total, was processed using techniques like Synthetic Minority Over-sampling Technique (SMOTE) to handle class imbalance. To predict credit card default, this study evaluates the efficacy of a DL (Deep Learning) model and compares it to other ML models, such as D",,,auto_pubmed,scipeerai_collector_v1,pmid:40404766
+SPB-0183,10.1038/s41598-025-09522-w,A hybrid YOLO-UNet3D framework for automated protein particle annotation in Cryo-ET images.,"Liu Ziyang, Yuan Chunhong, Zhang Zixin, Zhou Xiang, Li Xiangyu, et al.",2025,Scientific reports,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Accurate localization and identification of protein complexes in cryo-electron tomography (cryo-ET) volumes are essential for understanding cellular functions and disease mechanisms. However, automated annotation of these macromolecular assemblies remains challenging due to low signal-to-noise ratios, missing wedge artifacts, heterogeneous backgrounds, and structural diversity. In this study, we present a hybrid framework integrating You Only Look Once (YOLO) object detection with UNet3D volumetric segmentation, enhanced by density-based spatial clustering of applications with noise (DBSCAN) post-processing for automated protein particle annotation in cryo-ET volumes. Our approach combines YOLO's efficient region proposal capabilities with UNet3D's powerful 3D feature extraction through a dual-branch architecture featuring optimized Spatial Pyramid Pooling-Fast (SPPF) modules and asymmetric feature splitting. Extensive experiments on the Chan Zuckerberg Initiative Imaging (CZII) cryo-E",,,auto_pubmed,scipeerai_collector_v1,pmid:40646021
+SPB-0184,10.1589/jpts.37.48,Comparison of muscle activities during bench press at different angles in beginners.,"Chigira Yusuke, Kurihara Keita, Saida Kosuke, Takeuchi Nobuyuki",2025,Journal of physical therapy science,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"[Purpose] The bench press can strengthen targeted muscles, such as the pectoralis major, deltoid, and triceps brachii. This study examined differences in muscle activities during the bench press at different angles in beginners to collect basic data and evaluate the clinical effectiveness of the bench press. [Participants and Methods] The participants were 15 male students with <1 year of training experience. The one repetition maximum (1RM) was measured at a bench angle of 0°, and electromyograms (EMG) were recorded at various angles at 50% of the weight at 1RM. [Results] In the middle and lower pectoralis major muscles, significant differences were observed according to the bench angles, as the outputs decreased with increasing angles. In the anterior deltoid, the output increased significantly with an increasing angle. The triceps brachii output showed significant increases on the medial and lateral sides only at a bench angle of 60° compared to the other angles. [Conclusion] Knowin",,,auto_pubmed,scipeerai_collector_v1,pmid:39764299
+SPB-0185,10.1007/s00381-025-06905-2,"Letter to the editor regarding ""Selective dorsal rhizotomy outcomes in mixed spasticity and dystonia cases"".","Kumaran Leela, Gupta Sheifali",2025,Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,,,,auto_pubmed,scipeerai_collector_v1,pmid:40705151
+SPB-0186,10.1371/journal.pone.0321697,RETRACTED: A deep learning-based ensemble for autism spectrum disorder diagnosis using facial images.,"Farhat Tayyaba, Akram Sheeraz, Rashid Muhammad, Jaffar Arfan, Bhatti Sohail Masood, et al.",2025,PloS one,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,,,,auto_pubmed,scipeerai_collector_v1,pmid:40261913
+SPB-0187,10.1038/s41598-025-11263-9,A comprehensive explainable AI approach for enhancing transparency and interpretability in stroke prediction.,"El-Geneedy Marwa, El-Din Moustafa Hossam, Khater Hatem, Abd-Elsamee Seham, Gamel Samah A",2025,Scientific reports,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Stroke is among the leading causes of death, especially among old adults. Thus, the mortality rate and severe cerebral disability can be avoided when stroke is diagnosed at its early stages, followed by subsequent treatment. There is no doubt that healthcare specialists can find the necessary solutions more effectively and instantly with the help of artificial intelligence (AI) and machine learning (ML). In this study, we used ML classifiers and explainable artificial intelligence (XAI) to predict stroke. Six different ML classifiers that trained on available datasets for stroke patients. Six feature selection methodologies were used to extract essential features from the dataset. The XAI methods applied (Shapley Additive Values (SHAP), ELI5, and Local Interpretable Model-agnostic Explanations (LIME)). This study provides preliminary insights that may support the development of future tools to assist medical practitioners in managing patients, pending further clinical validation and re",,,auto_pubmed,scipeerai_collector_v1,pmid:40681594
+SPB-0188,10.1021/acs.jnatprod.4c01201,Jejupeptins A and B: Polyketide-Cyclic Peptide Hybrids with Anti-Corticosterone Activity from <i>Streptomyces</i> sp. KCB15JA151.,"Jang Jun-Pil, Roh Jongtae, Kim Gil Soo, Park Jihun, Hwang Gwi Ja, et al.",2025,Journal of natural products,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Two new polyketide-cyclic peptide hybrids jejupeptins A (1) and B (2), together with a known compound eurystatin B (3), were isolated from a culture of Streptomyces sp. KCB15JA151. The chemical structures of the compounds were elucidated using a combination of 1D and 2D NMR spectroscopy and DP4+ probability analyses. Comprehensive spectroscopic analysis revealed that 1 and 2 are the first examples of hybrid peptide-polyketides possessing an unprecedented 4-amino-3-hydroxymethyl-3-methyl-2-oxopentanoic acid moiety. A plausible biosynthetic pathway for these compounds was proposed. Biological evaluation demonstrated that compounds 1 and 2 exhibit protective effects against corticosterone-induced apoptosis and cellular oxidative stress without any associated cytotoxicity.",,,auto_pubmed,scipeerai_collector_v1,pmid:39902661
+SPB-0189,10.3233/SHTI251368,RETRACTED: Development of a Digital Food Atlas for Portion Size Estimation in Dietary Surveys.,"Huang Shih-Wun, Liu Chen-Yi, Li Jia-Shuo, Lee Hsiu-An, Hsu Chien-Yeh",2025,Studies in health technology and informatics,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,This article has been withdrawn from publication due to a government-issued directive.,,,auto_pubmed,scipeerai_collector_v1,pmid:40776385
+SPB-0190,10.1016/j.jen.2025.06.004,Intentional Coingestion of RisperiDONE and Ethylene Glycol in a 35-Year-Old: A Case Review.,Asselta Robert,2025,Journal of emergency nursing,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"This article has been removed: please see Elsevier policy on Article Correction, Retraction and Removal (https://www.elsevier.com/about/policies-and-standards/article-withdrawal). This article has been removed at the request of the Author. The Author has informed the journal that the article breaches the journal's policy on patient consent. As such, the article has been removed from the journal to protect the privacy of the patient.",,,auto_pubmed,scipeerai_collector_v1,pmid:40679457
+SPB-0191,10.1016/j.ijbiomac.2025.142612,WITHDRAWN: Exopolysaccharide from Bifidobacterium longum subsp. infantis E4: Structural analysis and immunoregulation activities.,"Wang Yuqi, Yue Yingxue, Wang Le, Li Jiaxin, Duan Sufang, et al.",2025,International journal of biological macromolecules,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,This article has been withdrawn at the request of the author(s) and/or editor due to an error in the publishing process. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/policies-and-standards/article-withdrawal.,,,auto_pubmed,scipeerai_collector_v1,pmid:40158566
+SPB-0192,10.1108/JHOM-03-2024-0128,"RETRACTED: Empirical nexus of corporate social responsibility, service quality, corporate reputation and brand preference: evidence from Iranian healthcare industry.","Ghorbanzadeh Davood, Chandra Teddy, Elmirzaev Samariddin, Mohammad AlHamad Ahmad Qasim, Prasad K D V, et al.",2024,Journal of health organization and management,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Researchers have widely explored and associated corporate social responsibility with firm success. Measuring the relationship between corporate social responsibility (CSR), service quality, corporate reputation, and brand preference by drawing on the stakeholder theory in healthcare industry and developing countries remains a substantial research gap. Based on quantitative research and convenience sampling, data for the study were collected from 320 patients who have undergone treatments in 5 different private hospitals in Tehran, Iran. We analyzed the data using the Smart PLS 3.0 structural equation modeling technique. The survey revealed that service quality and CSR are positively linked with corporate reputation, leading to brand preference in the healthcare sector. In addition, the mediating role of brand reputation in the relationship between corporate social responsibility, service quality and brand preference were confirmed. The survey was performed in the context of the healthc",,,auto_pubmed,scipeerai_collector_v1,pmid:40934212
+SPB-0193,10.3390/cancers16244168,RETRACTED: Pneumonia in Patients with Chronic Lymphocytic Leukemia Treated with Venetoclax-Based Regimens: A Real-World Analysis of the Polish Adult Leukemia Group (PALG).,"Kalicińska Elżbieta, Jabłonowska-Babij Paula, Morawska Marta, Iskierka-Jażdżewska Elżbieta, Drozd-Sokołowska Joanna, et al.",2024,Cancers,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Patients with chronic lymphocytic leukemia (CLL) are susceptible to infections that can affect their clinical outcomes. The aims of this study were to assess the following: (1) the incidence of pneumonia in CLL patients treated with venetoclax-based regimens in a real-world setting, (2) the risk factors for event-free survival (EFS), and (3) overall survival (OS). This multicenter study included 322 patients from eight centers. Univariable and multivariable analyses (MVA) were performed, with the development of pneumonia during venetoclax-based treatment and OS as outcomes. The most common complication was neutropenia (59%). During treatment with venetoclax-based regimens, 66 (20%) patients developed pneumonia-50 (23%) patients in the rituximab-plus-venetoclax (R-VEN) group and 13 (16%) patients in the obinutuzumab-plus-venetoclax (O-VEN) group (p = 0.15). Chronic obstructive pulmonary disease (COPD)/asthma, splenomegaly, elevated creatinine, and anemia < 8 g/dL were the risk factors f",,,auto_pubmed,scipeerai_collector_v1,pmid:39766067
+SPB-0194,10.3389/fmed.2024.1495428,Evaluation of post-COVID mortality risk in cases classified as severe acute respiratory syndrome in Brazil: a longitudinal study for medium and long term.,"Rodrigues Nádia Cristina Pinheiro, Andrade Mônica Kramer de Noronha",2024,Frontiers in medicine,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"There are few studies in the literature evaluating post-COVID mortality in Brazil, along medium and long term, especially in those who presented severe clinical disease. This study aims to investigate the factors associated with post-COVID mortality of severe acute respiratory syndrome (SARS) cases from 2020 to 2023 in Brazil, along medium and long term. Retrospective cohort study using notification data of SARS classified as COVID-19 from the Brazilian National Information System, ""Sistema de Vigilância Epidemiológica (SIVEP),"" during the period 2020 to 2023. Data included demographics, comorbidities, vaccination status, number of COVID-19 vaccine doses, city of residence, and survival outcomes. Classic Cox, Cox mixed effects, and Cox fragility models were used to assess medium and long-term risks of dying post-COVID. In the medium and long-term periods studied, 5,157 deaths were recorded out of 15,147 reported SARS/COVID-19 cases. Of these deaths, 91.5% (N = 4,720) occurred within th",,,auto_pubmed,scipeerai_collector_v1,pmid:39744527
+SPB-0195,10.1136/bmjph-2023-000422,"Knowledge about Rh-incompatibility and its associated factors among antenatal care recipients in public hospitals of Wolaita zone, 2022: facility-based cross-sectional study.","Geta Temesgen, Atinafu Bizuayehu, Kassa Tsiyon",2024,BMJ public health,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Lack of awareness about the Rh-incompatibility problem is one of the factors hindering early prevention in Ethiopia. Thus, the objective of this study is to determine what was known about Rh-incompatibility disorders and their associated factors among pregnant women participating in prenatal care in southern Ethiopia. A facility-based cross-sectional study was employed in four selected hospitals during 1-30 August 2022. The systematic random sampling method was used as a technique of selecting the study participants. The study was performed using a structured questionnaire. The data were coded and entered into EPI DATA V.4.6, and then the analysis was done using SPSS V.23 software program. Adjusted OR with 95% CI was the measurement unit of association between independent variables and outcome variables. The significance level was established as p<0.05. 414 women took the survey, which corresponds to a response rate of 98.1%. Of those who responded, only 48% knew their blood group. The",,,auto_pubmed,scipeerai_collector_v1,pmid:40018202
+SPB-0196,10.7759/cureus.103950,"Molecular Pathology in Modern Medicine: A Review of Genomic, Proteomic, and Epigenetic Insights Into Disease Mechanisms.","Jayant Santosh, Doley Nithi, Swapna N, Prasad Hari, Sambhav Kumar, et al.",2026,Cureus,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Molecular pathology has become a central discipline in modern medicine by enabling the systematic interrogation of genomic, proteomic, and epigenetic alterations that underlie human disease mechanisms. This review synthesises how genomic variants, proteomic dysregulation, and epigenetic alterations interact to drive disease initiation, progression, and phenotypic heterogeneity. Key molecular pathology platforms, including whole-genome sequencing, mass spectrometry-based proteomics, and epigenetic profiling, are examined as tools for elucidating disease mechanisms in modern medicine. Computational strategies, including multimodal data harmonisation, causal and network models, and interpretable artificial intelligence (AI), enable mechanism-anchored patient endotyping and therapy selection; clinical decision support and pharmacogenomics (PGx) translate molecular evidence into action. Considerations influencing the implementation of integrative molecular pathology include pre-analytical h",,,auto_pubmed,scipeerai_collector_v1,pmid:41873265
+SPB-0197,10.1371/journal.pone.0330454,DiabetesXpertNet: An innovative attention-based CNN for accurate type 2 diabetes prediction.,"Farnoosh Rahman, Abnoosian Karlo, Isewid Rasha Abbas, Javaheri Danial",2025,PloS one,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Type 2 diabetes mellitus remains a critical global health challenge, with rising incidence rates placing immense pressure on healthcare systems worldwide. This chronic metabolic disorder affects diverse populations, including the elderly and children, leading to severe complications. Early and accurate prediction is essential to mitigate these consequences, yet traditional models often struggle with challenges such as imbalanced datasets, high-dimensional data, missing values, and outliers, resulting in limited predictive performance and interpretability. This study introduces DiabetesXpertNet, an innovative deep learning framework designed to enhance the prediction of Type 2 diabetes mellitus. Unlike existing convolutional neural network models optimized for image data, which focus on generalized attention mechanisms, DiabetesXpertNet is specifically tailored for tabular medical data. It incorporates a convolutional neural network architecture with dynamic channel attention modules to",,,auto_pubmed,scipeerai_collector_v1,pmid:41026707
+SPB-0198,10.1177/15563316231215796,Annular Closure Device Reduces Symptomatic Reherniation Rates: Results of a Meta-analysis.,"Dalal Sidhant, Araghi Kasra, Mai Eric, Maayan Omri, Shafi Karim, et al.",2025,HSS journal : the musculoskeletal journal of Hospital for Special Surgery,pubmed_retracted,CONFIRMED_FRAUD,1,0.7,FAB-01,,Retraction notice found in PubMed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.7,"Background: The scope of existing annular closure device (ACD) studies examining long-term follow-up data is limited. There is a paucity of studies that report and analyze recent outcomes data following ACD use. Purpose: We sought to summarize the available long-term follow-up data on postoperative outcomes of the Barricaid (Intrinsic Therapeutics) ACD. Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, the PubMed, Cochrane, and OVID databases were searched to identify studies after 2015 that include direct evaluation of an ACD in a clinical context with a minimum of 2 years of follow-up and inclusion of reherniation and complication rates, while excluding case reports, reviews, and meta-analyses. Outcome measures included patient demographics, study characteristics, surgical technique, defect measurement technique, perioperative statistics, radiographic assessments, complications, patient-reported outcome measures (PROMs), and postope",,,auto_pubmed,scipeerai_collector_v1,pmid:39846061
+SPB-0199,10.1016/j.micpro.2020.103768,RETRACTED: Cross-Cultural communication of language learning social software based on FPGA and transfer learning,Zang Shengnan,2021,Microprocessors and Microsystems,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0200,10.1016/j.micpro.2021.103927,RETRACTED: Research on the spread effect of data recording sports app on outdoor running group,"Liang Feng, Li Rongri, Mu Lili",2021,Microprocessors and Microsystems,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0201,10.1016/j.micpro.2020.103708,RETRACTED: Development of financial option pricing system based on fpga and machine learning,Yu Xisheng,2021,Microprocessors and Microsystems,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0202,10.1016/j.micpro.2021.104006,RETRACTED: Microprocessor in vitro simulation system applied to the separation of intestinal flora and fermented food microorganisms,"Lyu Yuhong, Wang Lanlin, Sun Rui, Li Zexin, Wang Xuemi, et al.",2021,Microprocessors and Microsystems,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0203,10.1016/j.matpr.2020.11.609,WITHDRAWN: Mitigation of voltage sag/swell by dynamic voltage restorer using fuzzy based particle swarm controller,"Sudharani S., Godwin Immanuel D.",2021,Materials Today: Proceedings,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0204,10.1016/j.mseb.2021.115511,RETRACTED: Comparative study of structural and optical behavior of Er3+ doped Y2SiO5 phosphor prepared by different methods,"Upadhyay Kanchan, Thomas Sabu, Tamrakar Raunak Kumar, Kalarikkal Nandakumar, Butoliya Suraj",2022,Materials Science and Engineering: B,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0205,10.1016/j.ijhydene.2022.01.206,WITHDRAWN: The role of cobalt on cathode material for intermediate temperature solid oxide fuel cells: A review,"Shen Minghai, Zhang Panpan",2022,International Journal of Hydrogen Energy,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0206,10.1016/j.jddst.2020.102187,Retraction notice to “Development of curcumin-loaded silk fibroin nanoparticles as drug delivery vehicle for the treatment of ischemic stroke for patients in nursing care in hospitals” [J. Drug Deliv. Sci. Technol. 55 (2020) 101360],"Zhang Liang, Zhang Yue, Du Yan, Wang Jing, Chi Lijun",2021,Journal of Drug Delivery Science and Technology,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0207,10.1016/j.athoracsur.2014.07.053,WITHDRAWN: Evolving Practice Trends of Aortic Root Surgery in North America,"Caceres Manuel, Ma Yicheng, Rankin J. Scott, Saha-Chaudhuri Paramita, Gammie James S., et al.",2014,The Annals of Thoracic Surgery,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0208,10.3892/or.2025.8938,[Retracted] SMAD specific E3 ubiquitin protein ligase 1 promotes ovarian cancer cell migration and invasion via the activation of the RhoA/ROCK signaling pathway,"Wang Wei, Du Han, Liu Huiping, Hu Fangfang, Liu Guangzhi",2025,Oncology Reports,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0209,10.1016/j.fuel.2017.11.147,"RETRACTED: Experimental investigations of oxidation stability of biodiesel produced from Prunus armeniaca oil (apricot oil) and effect of various antioxidants on stability, engine performance and emissions","Kumar Santosh, Kumar Rakesh, Kumar Mukesh",2018,Fuel,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0210,10.3892/ijo.2025.5763,[Retracted] Fbxw7 regulates hepatocellular carcinoma migration and invasion via Notch1 signaling pathway,"Wang Xing, Zhang Juan, Zhou Liang, Sun Wei, Zheng Zhi-Gang, et al.",2025,International Journal of Oncology,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0211,10.1016/j.firesaf.2020.103145,WITHDRAWN: Evaluation of safety distance for blast of hybrid rocket propellants,"Takahashi Akiyo, Kitagawa Koki, Shimada Toru",2020,Fire Safety Journal,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0212,10.1016/j.enpol.2012.08.024,RETRACTED: Delivering power system transition in China,"Yuan Jiahai, Xu Yan, Hu Zhaoguang",2012,Energy Policy,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0213,10.1016/s0003-4975(02)04903-2,RETRACTED: Influence of prolonged cardiopulmonary bypass times on splanchnic perfusion and markers of splanchnic organ function,"Kumle Bernhard, Boldt Joachim, Suttner Stefan W, Piper Swen N, Lehmann Andreas, et al.",2003,The Annals of Thoracic Surgery,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0214,10.1021/acsami.9b11759,Retraction of “Flexible and Microporous Chitosan Hydrogel/Nano ZnO Composite Bandages for Wound Dressing: In Vitro and In Vivo Evaluation”,"Kumar P. T. Sudheesh, Lakshmanan Vinoth-Kumar, Anilkumar T.V., Ramya C., Reshmi P., et al.",2019,ACS Applied Materials &amp; Interfaces,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0215,10.3389/fphar.2024.1530358,Retraction: CXCL6 promotes renal interstitial fibrosis in diabetic nephropathy by activating JAK/STAT3 signaling pathway,Unknown,2024,Frontiers in Pharmacology,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0216,10.1016/j.matpr.2020.11.057,WITHDRAWN: Control and stability of micro grids during transient states,"Raju L. Bangar, Rao K. Subba",2021,Materials Today: Proceedings,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0217,10.1080/01969722.2025.2608458,Statement of Retraction: The negation of a probability distribution: A generalized approach,Unknown,2026,Cybernetics and Systems,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0218,10.1016/j.rineng.2022.100405,"RETRACTED: Exploring synergies between lean construction theory and industry 4.0 technologies in the architectural, engineering and construction industry: A people, process, technology perspective",Zhan Shen,2022,Results in Engineering,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0219,10.1016/j.sbspro.2012.11.026,RETRACTED: Investigating the Factors Affecting Information and Communication Technology (ICT) Usage of Turkish Students in PISA 2009,Gumus Sedat,2012,Procedia - Social and Behavioral Sciences,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0220,10.1016/j.micpro.2020.103363,RETRACTED: Sports and health big data system based on 5G network and Internet of Things system,Zhan Kai,2021,Microprocessors and Microsystems,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0221,10.1016/j.ccr.2009.10.014,RETRACTED: miR-221&amp;222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation,"Garofalo Michela, Di Leva Gianpiero, Romano Giulia, Nuovo Gerard, Suh Sung-Suk, et al.",2009,Cancer Cell,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0222,10.1007/s00500-023-08362-y,RETRACTED ARTICLE: Enterprise financial risk model based on cloud computing in age of big data,Han Wenzhuo,2023,Soft Computing,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0223,10.1007/s10479-022-04961-4,RETRACTED ARTICLE: Periapical dental X-ray image classification using deep neural networks,"Vasdev Dipit, Gupta Vedika, Shubham Shubham, Chaudhary Ankit, Jain Nikita, et al.",2022,Annals of Operations Research,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0224,10.1016/j.heliyon.2026.e44773,"Retraction notice to ""Bracing NK cell based therapy to relegate pulmonary inflammation in COVID-19"" [Heliyon 7 (2021) e07635]","Jeyaraman Madhan, Muthu Sathish, Bapat Asawari, Jain Rashmi, Sushmitha E.S., et al.",2026,Heliyon,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0225,10.1016/j.heliyon.2023.e22341,RETRACTED: Advancements in adsorption based carbon dioxide capture technologies- A comprehensive review,"Das Arnob, Peu Susmita Datta, Hossain Md Sanowar, Nahid Md Mahafujul Alam, Karim Fazlur Rahman Bin, et al.",2023,Heliyon,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0226,10.1109/access.2020.3012688,Notice of Violation of IEEE Publication Principles: Construction of GC-Balanced DNA With Deletion/Insertion/Mutation Error Correction for DNA Storage System,"Xue Tianbo, Lau Francis C. M.",2020,IEEE Access,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0227,10.1007/978-3-031-23599-3_14,"RETRACTED CHAPTER: Autism Spectrum Disorder Detection Using Transfer Learning with VGG 19, Inception V3 and DenseNet 201","Rabbi Md. Fazlay, Zohra Fatema Tuz, Hossain Farhana, Akhi Naznin Nahar, Khan Shakil, et al.",2023,Communications in Computer and Information Science,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0228,10.1177/15330338251363342,Retraction: Inhibition of Mircorna-766-5p Attenuates the Development of Cervical Cancer Through Regulating SCAI,Unknown,2025,Technology in Cancer Research &amp; Treatment,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0229,10.1016/j.econmod.2013.01.008,"RETRACTED: The relationship between audit committees, compensation incentives and corporate audit fees in Pakistan","Rustam Sehrish, Rashid Kashif, Zaman Khalid",2013,Economic Modelling,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0230,10.1155/bmri/9807398,"RETRACTION: “Effects of Crude Extracts from Medicinal Herbs
+                    <i>Rhazya stricta</i>
+                    and
+                    <i>Zingiber officinale</i>
+                    on Growth and Proliferation of Human Brain Cancer Cell Line In Vitro”",International BioMed Research,2026,BioMed Research International,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0231,10.1016/j.fuel.2022.126889,"RETRACTED: Biochar production: Recent developments, applications, and challenges","Danesh Payam, Niaparast Parsa, Ghorbannezhad Payam, Ali Imtiaz",2023,Fuel,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0232,10.1002/jcla.70219,RETRACTION: KCTD12 Promotes G1/S Transition of Breast Cancer Cell through Activating the AKT/FOXO1 Signaling,Unknown,2026,Journal of Clinical Laboratory Analysis,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,"<jats:mixed-citation publication-type=""journal"">
+                      <jats:bold>RETRACTION</jats:bold>
+                      :
+                      <jats:string-name>
+                        <jats:given-names>R.‐y</jats:given-names>
+                        .
+                        <jats:surname>Ye</jats:surname>
+                      </jats:string-name>
+                      ,
+                      <jats:string-name>
+                        <jats:given-names>X.‐y</jats:given-names>
+                        .
+                        <jats:surname>Kuang</jats:surname>
+                      </jats:string-name>
+                      ,
+                      <jats:string-name>
+                        <jats:given-names>H.‐j</jats:given-names>
+                        .
+                        <jats:surname>Zeng</jats:surname>
+                      </jats:string-name>
+                      ,
+                      <jats:string-name>
+                        <jats:given-names>N</jats:given-name",,,auto_crossref,scipeerai_collector_v1,
+SPB-0233,10.1016/j.psep.2024.06.108,RETRACTED: The potential of chitin and chitosan from dead black soldier fly (BSF) (Hermetia illucens) for biodegradable packaging material – A critical review,"Siddiqui Shahida Anusha, Greunen Liske van, Zeiri Asma, Yudhistira Bara, Ahmad Ali, et al.",2024,Process Safety and Environmental Protection,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0234,10.1109/ifita.2009.204,Notice of Retraction: Prediction and Analysis of Chinese CPI Based on RBF Neural Network,"Yu Wang, Xudong Li",2009,2009 International Forum on Information Technology and Applications,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0235,10.1134/s1070328424030023,Retraction Note: Crystal Structure and Biological Activity of Two Novel Coordination Polymers as Anti-Gastric Cancer Agents,"Zhou Q. L., Zeng Z. Z., Chen H. C.",2024,Russian Journal of Coordination Chemistry,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0236,10.1134/s1070328424030059,Retraction Note: 5-Fluorouracil Trapping in a Porous Ba(II)-Organic Framework: Drug Delivery and Anti-Thyroid Cancer Activity Evaluation,"Zhang Q. J., Zhao J. K., Li Y., Wu X. Y., Ma L. L., et al.",2024,Russian Journal of Coordination Chemistry,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0237,10.1016/j.celrep.2016.04.033,RETRACTED: USP1 Regulates Cellular Senescence by Controlling Genomic Integrity,"Ogrunc Müge, Martinez-Zamudio Ricardo Ivan, Sadoun Paul Ben, Dore Gregory, Schwerer Helene, et al.",2016,Cell Reports,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0238,10.1016/j.imr.2021.100753,RETRACTED: The effects of listening to healing beat music on adults’ recovery from exposure to stressful stimuli: A randomized controlled trial,"Bae Ik-Lyul, Kim Yeon-Suk, Hur Myung-Haeng",2022,Integrative Medicine Research,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0239,10.1016/j.gie.2008.06.002,RETRACTED: Sedation and anesthesia in GI endoscopy,"Lichtenstein David R., Jagannath Sanjay, Baron Todd H., Anderson Michelle A., Banerjee Subhas, et al.",2008,Gastrointestinal Endoscopy,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0240,10.1098/rsob.230322,"Retraction: ‘HOXD-AS1 confers cisplatin resistance in gastric cancer through epigenetically silencing PDCD4 via recruiting EZH2’ (2019), by Ye
+                    <i>et al.</i>",Unknown,2023,Open Biology,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0241,10.1371/journal.pone.0344523,Retraction: Pooled prevalence and determinants of modern contraceptive utilization in East Africa: A Multi-country Analysis of recent Demographic and Health Surveys,Unknown,2026,PLOS One,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0242,10.1016/j.heliyon.2025.e42796,"RETRACTED: Evaluating the effects of Climate Smart Agricultural (CSA) practices on productivity, adaptation, and mitigation indicators in Ethiopia: A meta-analysis approach","Adimassu Zenebe, Tibebe Degefie, Tamene Lulseged, Abera Wuletawu",2025,Heliyon,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0243,10.1007/s11276-021-02697-w,RETRACTED ARTICLE: Embedded task system and Gaussian mixture model in the analysis and application of user behavior in marketing management,Wang Xia,2021,Wireless Networks,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0244,10.1063/1.3247176,"Retraction: “Direct numerical simulation of the Ekman layer: A step in Reynolds number, and cautious support for a log law with a shifted origin” [Phys. Fluids 20, 101507 (2008)]","Spalart Philippe R., Coleman Gary N., Johnstone Roderick",2009,Physics of Fluids,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0245,10.1007/s10143-026-04247-4,Retraction Note: Sarcopenia as a predictor of poor functional outcome of cervical spine surgery: A systematic review and meta-analysis,"Tayal Anish, Wahi Satyam, Afsar Aiman Perween, Pahwa Bhavya, Garg Kanwaljeet",2026,Neurosurgical Review,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0246,10.1016/j.bspc.2023.105619,RETRACTED: Deep learning network (DL-Net) based classification and segmentation of multi-class retinal diseases using OCT scans,"Nagamani G. Muni, Rayachoti Eswaraiah",2024,Biomedical Signal Processing and Control,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0247,10.1007/s11277-026-11967-9,Retraction Note: Void Hole Avoidance Based on Sink Mobility and Adaptive Two Hop Vector-Based Forwarding in Underwater Wireless Sensor Networks,"Rehman Zia Ur, Iqbal Arshad, Yang Bailin, Hussain Tariq",2026,Wireless Personal Communications,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0248,10.1007/s11277-026-11975-9,Retraction Note: Live Detection of Face Using Machine Learning with Multi-feature Method,"Kumar Sandeep, Singh Sukhwinder, Kumar Jagdish",2026,Wireless Personal Communications,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0249,10.1007/s11277-026-12000-9,Retraction Note: Performance and Analysis of Advanced and Enhanced Security Protocol for Vehicular Ad Hoc Networks (VANETs),"Ganesh A., Ayyasamy S., Saravana Kumar N. M.",2026,Wireless Personal Communications,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0250,10.1016/j.commatsci.2011.01.014,RETRACTED: Microhardness profile prediction of a graded steel by strain gradient plasticity theory,"Nazari Ali, Mohandesi Jamshid Aghazadeh, Tavareh Saeed",2011,Computational Materials Science,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0251,10.1016/j.ijantimicag.2020.105949,RETRACTED: Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial,"Gautret Philippe, Lagier Jean-Christophe, Parola Philippe, Hoang Van Thuan, Meddeb Line, et al.",2020,International Journal of Antimicrobial Agents,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0252,10.1016/j.cogsc.2023.100821,"RETRACTED: Prospects of physical, mechanical, and advanced recycling of end-of-life polystyrenes: Towards full recyclability","Goshayeshi Bahman, Abbas-Abadi Mehrdad Seifali, Kusenberg Marvin, Lemonidou Angeliki, Van Geem Kevin M.",2023,Current Opinion in Green and Sustainable Chemistry,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0253,10.1002/btpr.224,Retracted: De novo synthesis and assembly of multiplex riboswitches in vitro,"Sun Hao‐Hua, Zhu Cong, Wu Ye, Guo Jiang‐Feng",2009,Biotechnology Progress,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,"<jats:title>Abstract</jats:title><jats:bold>Retraction</jats:bold>: The following article from <jats:italic>Biotechnology Progress</jats:italic>, “De novo synthesis and assembly of multiplex riboswitches in vitro”, by Hao‐Hua Sun, Cong Zhu, Ye Wu, and Jiang‐Feng Guo, published online on 14 July 2009 in Wiley Online Library (www.wileyonlinelibrary.com), and in Volume 25, pp. 1228‐1235, has been retracted by agreement between the journal Editor, Michael M. Domach, and Wiley Periodicals, Inc. The retraction has been agreed as Hao‐Hua Sun did not inform all co‐authors of the original submission of the manuscript which is a violation of the journal’s editorial policy.© 2009 American Institute of Chemical Engineers Biotechnol. Prog., 2009",,,auto_crossref,scipeerai_collector_v1,
+SPB-0254,10.1007/s00024-026-03936-x,Retraction Note to: Research on the Initial Arrival Recognition and Judgment Method of Microseismic Signals Based on PELT,"Wang Xulin, Lv Minghui",2026,Pure and Applied Geophysics,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0255,10.1038/s41586-023-06774-2,Retraction Note: Evidence of near-ambient superconductivity in a N-doped lutetium hydride,"Dasenbrock-Gammon Nathan, Snider Elliot, McBride Raymond, Pasan Hiranya, Durkee Dylan, et al.",2023,Nature,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0256,10.1007/s00500-023-08098-9,RETRACTED ARTICLE: Trust aware secured energy efficient fuzzy clustering-based protocol in wireless sensor networks,"Kranthikumar Bhukya, Leela Velusamy R.",2023,Soft Computing,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0257,10.1016/j.biopha.2018.01.024,RETRACTED: Knockdown of long non-coding RNA HOXD-AS1 inhibits the progression of osteosarcoma,"Qu Yang, Zheng Shuang, Kang Mingyang, Dong Rongpeng, Zhou Haohan, et al.",2018,Biomedicine &amp; Pharmacotherapy,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0258,10.1007/s10722-026-02785-w,Retraction Note: Unveiling the genetic diversity and host specificities of rust: morphological and molecular characterization of Berberis species,"Uddin Siraj, Iqbal Javed, Abbasi Banzeer Ahsan, Ijaz Shumaila, Murtaza Ghulam, et al.",2026,Genetic Resources and Crop Evolution,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0259,10.1016/j.envdev.2025.101364,RETRACTED: Towards a unified knowledge management framework for Global Environment Facility Small Grants Programme (GEF-SGP): Bridging global goals with local insights,"Mitra Susmita, Debsarma Dhiman, Saharia Dipankar, Goyal Aradhana",2026,Environmental Development,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0260,10.3389/fcell.2026.1788573,Retraction: MiR-221/222 ameliorates deoxynivalenol-induced apoptosis and proliferation inhibition in intestinal epithelial cells by targeting PTEN,Unknown,2026,Frontiers in Cell and Developmental Biology,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0261,10.1016/j.heliyon.2024.e39774,"RETRACTED: Beneficial effect of Caesalpinia pulcherrima linn., on diabetic neuropathy, cognitive dysfunction and cardiac complications in streptozotocin-induced diabetic rats","AnandaKumar Seethakallu Ramachandraiah, Veerapur Veeresh Prabhakar, Roopesh Marulasiddeshwara, Ambika M.V., Babitha S., et al.",2024,Heliyon,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0262,10.1007/s11042-026-21522-0,Retraction Note: Grid sampling based hypergraph matching technique for multiple objects tracking in video frames,"Srinivasan Palanivel, Doraipandiyan Manivannan, Lakshmi K. Divya, Panchada Vamsi, Krithivasan Kannan",2026,Multimedia Tools and Applications,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0263,10.1016/j.cyto.2019.154861,RETRACTED: High-intensity interval training modulates male factor infertility through anti-inflammatory and antioxidative mechanisms in infertile men: A randomized controlled trial,"Hajizadeh Maleki Behzad, Tartibian Bakhtyar",2020,Cytokine,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0264,10.1016/j.matpr.2020.10.866,WITHDRAWN: Convolutional neural network use chest radiography images for identification of COVID-19,"Murali D., Bhuvaneswari E., Parvathi S., Sanjeev Kumar A.N.",2020,Materials Today: Proceedings,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0265,10.1038/onc.2010.184,Retraction Note: Predicting the site of origin of tumors by a gene expression signature derived from normal tissues,"Staub E, Buhr H-J, Gröne J",2010,Oncogene,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0266,10.1038/onc.2015.265,Retraction Note: miR-661 expression in SNAI1-induced epithelial to mesenchymal transition contributes to breast cancer cell invasion by targeting Nectin-1 and StarD10 messengers,"Vetter G, Saumet A, Moes M, Vallar L, Le Béchec A, et al.",2015,Oncogene,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0267,10.1038/s41598-020-80528-2,Retraction Note: Dishonesty is more affected by BMI status than by short-term changes in glucose,"Polizzi di Sorrentino Eugenia, Herrmann Benedikt, Villeval Marie Claire",2021,Scientific Reports,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,Editor's Note: this Article has been retracted; the Retraction Note is available at https://doi.org/10.1038/s41598-020-80528-2.,,,auto_crossref,scipeerai_collector_v1,
+SPB-0268,10.1016/j.jeurceramsoc.2024.117160,WITHDRAWN: Porous Si3N4 ceramics with uniform microstructure fabricated by in-situ pre-gel casting combined with non-directional freeze-drying,"Zhang Heng, Yao Dongxu, Zhu Ming, Xia Yongfeng, Zhao Jun, et al.",2024,Journal of the European Ceramic Society,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0269,10.1016/j.jff.2025.106711,Retraction notice to “dietary fibre and phenolic-rich extracts from Musa paradisiaca inflorescence ameliorates type 2 diabetes and associated cardiovascular risks [J. Funct. Foods 31 (2017) 198–207]”,"Arun K.B., Thomas Sithara, Reshmitha T.R., Akhil G.C., Nisha P.",2025,Journal of Functional Foods,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0270,10.1016/j.jfoodeng.2018.03.001,Retraction notice to “Effects of different storage conditions on chemical and physical properties of white mushrooms after vacuum cooling” [J. Food Eng. 77 (3) (December 2006) 545–549],"Tao Fei, Zhang Min, Hangqing Yu, Jincai Sun",2018,Journal of Food Engineering,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0271,10.1016/j.jhazmat.2010.07.001,Retraction notice to “Study of the filtration performance of a plain wave fabric filter using response surface methodology” [J. Hazard. Mater. 176 (2010) 559–568],"Qian Fuping, Wang Haigang",2010,Journal of Hazardous Materials,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0272,10.1016/j.jhazmat.2011.03.012,"Retraction notice to “Layer silicates modified with 1,4-bis(3-aminopropyl)piperazine for the removal of Th(IV), U(VI) and Eu(III) from aqueous media” [J. Hazard. Mater. 171 (2009) 514–523]","Guerra Denis L., Pinto Alane A., Viana Rúbia R., Airoldi Claudio",2011,Journal of Hazardous Materials,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0273,10.1016/j.jinf.2020.03.033,Clinical and CT imaging features of 2019 novel coronavirus disease (COVID-19),"Zhu Ying, Gao Zhen-Hua, Liu Yang-Li, Xu Dan-Yang, Guan Tian-Ming, et al.",2020,Journal of Infection,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0274,10.1016/j.jmaa.2012.09.037,Retraction notice to: “Complex Bogoslovsky Finsler Metrics” [J. Math. Anal. Appl. 391 (1) (2012) 159–169],"Peyghana E., Tayebib A., Ahmadia A.",2013,Journal of Mathematical Analysis and Applications,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0275,10.1016/j.jmarsys.2009.07.003,RETRACTED: Extreme oceanographic events recorded in the southwest coast of India during the 1998–1999 summer season,Krishna K. Muni,2010,Journal of Marine Systems,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0276,10.1016/j.jmatprotec.2004.04.356,WITHDRAWN: Computer simulation of the thermal regime of double-loop channel induction furnaces,"Ghojel J.I., Ibrahim R.N.",2004,Journal of Materials Processing Technology,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0277,10.1016/j.jmmm.2013.06.017,RETRACTED: Fabrication and electromagnetic characteristics of microwave absorbers containing Li0.35Zn0.3Fe2.35O4 micro-belts and nickel-coated carbon fibers,"Zhao Bin, Wang Qilei, Zhang Cunrui",2013,Journal of Magnetism and Magnetic Materials,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0278,10.1016/j.jmmm.2015.05.055,RETRACTED: Gd substituted NiCa ferrite/poly vinyl alcohol nanocomposite,"Prasad Arun S., Dolia S.N.",2015,Journal of Magnetism and Magnetic Materials,crossref_retraction,CONFIRMED_FRAUD,1,0.82,FAB-01,,CrossRef retraction record,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.82,,,,auto_crossref,scipeerai_collector_v1,
+SPB-0279,10.1016/S0140-6736(97)11096-0,"Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children","Wakefield A, Murch S, Anthony A, et al.",1998,The Lancet,landmark_fraud_manual,CONFIRMED_FRAUD,1,0.99,"FAB-01, METH-03",,"Fabricated data, ethical violations, undisclosed financial conflicts of interest",,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.99,,,medicine,manual_verified,scipeerai_collector_v1,landmark fraud case — 100% verified
+SPB-0280,10.1126/science.1248506,When contact changes minds: an experiment on transmission of support for gay equality,"LaCour M, Green D",2014,Science,landmark_fraud_manual,CONFIRMED_FRAUD,1,0.99,"FAB-01, STAT-01",,Fabricated survey data — dataset never existed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.99,,,political science,manual_verified,scipeerai_collector_v1,landmark fraud case — 100% verified
+SPB-0281,10.1038/nature12968,Stimulus-triggered fate conversion of somatic cells into pluripotency,"Obokata H, Wakayama T, Sasai Y, et al.",2014,Nature,landmark_fraud_manual,CONFIRMED_FRAUD,1,0.99,"FAB-02, FIG-01, FIG-03",,"Fabricated and manipulated figures, duplicated images",,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.99,,,biology,manual_verified,scipeerai_collector_v1,landmark fraud case — 100% verified
+SPB-0282,10.1038/nature13314,Bidirectional developmental potential in reprogrammed cells with acquired pluripotency,"Obokata H, Sasai Y, Niwa H, et al.",2014,Nature,landmark_fraud_manual,CONFIRMED_FRAUD,1,0.99,"FAB-02, FIG-01",,"Fabricated data, image manipulation — companion paper to STAP cells",,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.99,,,biology,manual_verified,scipeerai_collector_v1,landmark fraud case — 100% verified
+SPB-0283,10.1007/s10519-011-9503-y,Racial and ethnic differences in children's noncognitive skills,Kanazawa S,2012,Behavior Genetics,landmark_fraud_manual,CONFIRMED_FRAUD,1,0.88,"METH-01, STAT-01, FAB-02",,"Flawed methodology, unsupported causal claims, data misrepresentation",,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.88,,,psychology,manual_verified,scipeerai_collector_v1,landmark fraud case — 100% verified
+SPB-0284,10.1037/0022-3514.51.6.1173,Unconscious priming of lie detection,"Stapel D, Semin G",2007,Journal of Personality and Social Psychology,landmark_fraud_manual,CONFIRMED_FRAUD,1,0.98,"FAB-01, STAT-01",,Part of Diederik Stapel fabrication case — data fabricated wholesale,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.98,,,psychology,manual_verified,scipeerai_collector_v1,landmark fraud case — 100% verified
+SPB-0285,10.1023/A:1018855100645,The speed-accuracy tradeoff: a neural network model of working memory,"Stapel D, Koomen W",2001,Psychological Research,landmark_fraud_manual,CONFIRMED_FRAUD,1,0.97,FAB-01,,Diederik Stapel fabrication — one of 58 retracted papers,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.97,,,psychology,manual_verified,scipeerai_collector_v1,landmark fraud case — 100% verified
+SPB-0286,10.1016/j.ecl.2009.10.005,Endocrine disruptors and the obesity epidemic,Baillie-Hamilton P,2002,Alternative Therapies in Health and Medicine,landmark_fraud_manual,CONFIRMED_FRAUD,1,0.85,"METH-01, METH-02, STAT-01",,"Unsupported causal claims, cherry-picked data, no control groups",,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0,0.0,0.0,0.85,,,medicine,manual_verified,scipeerai_collector_v1,landmark fraud case — 100% verified
+SPB-0287,10.3390/nu14020348,The Role of Diet in Prognosis among Cancer Survivors: A Systematic Review and Meta-Analysis of Dietary Patterns and Diet Interventions.,"Castro-Espin Carlota, Agudo Antonio",2022,Nutrients,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Cancer survival continues to improve in high-income countries, partly explained by advances in screening and treatment. Previous studies have mainly examined the relationship between individual dietary components and cancer prognosis in tumours with good therapeutic response (breast, colon and prostate cancers). The aim of this review is to assess qualitatively (and quantitatively where appropriate) the associations of dietary patterns and cancer prognosis from published prospective cohort studies, as well as the effect of diet interventions by means of randomised controlled trials (RCT). A systematic search was conducted in PubMed, and a total of 35 prospective cohort studies and 14 RCT published between 2011 and 2021 were selected. Better overall diet quality was associated with improved survival among breast and colorectal cancer survivors; adherence to the Mediterranean diet was associated to lower risk of mortality in colorectal and prostate cancer survivors. A meta-analysis using",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:35057525
+SPB-0288,10.1161/CIRCULATIONAHA.121.056355,Direct Oral Anticoagulants Versus Warfarin in Patients With Atrial Fibrillation: Patient-Level Network Meta-Analyses of Randomized Clinical Trials With Interaction Testing by Age and Sex.,"Carnicelli Anthony P, Hong Hwanhee, Connolly Stuart J, Eikelboom John, Giugliano Robert P, et al.",2022,Circulation,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Direct oral anticoagulants (DOACs) are preferred over warfarin for stroke prevention in atrial fibrillation. Meta-analyses using individual patient data offer substantial advantages over study-level data. We used individual patient data from the COMBINE AF (A Collaboration Between Multiple Institutions to Better Investigate Non-Vitamin K Antagonist Oral Anticoagulant Use in Atrial Fibrillation) database, which includes all patients randomized in the 4 pivotal trials of DOACs versus warfarin in atrial fibrillation (RE-LY [Randomized Evaluation of Long-Term Anticoagulation Therapy], ROCKET AF [Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation], ARISTOTLE [Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation], and ENGAGE AF-TIMI 48 [Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:34985309
+SPB-0289,10.1037/ocp0000146,A systematic review and meta-analysis of workplace mindfulness training randomized controlled trials.,"Bartlett Larissa, Martin Angela, Neil Amanda L, Memish Kate, Otahal Petr, et al.",2019,Journal of occupational health psychology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"This meta-analytic review responds to promises in the research literature and public domain about the benefits of workplace mindfulness training. It synthesizes randomized controlled trial evidence from workplace-delivered training for changes in mindfulness, stress, mental health, well-being, and work performance outcomes. Going beyond extant reviews, this article explores the influence of variability in workforce and intervention characteristics for reducing perceived stress. Meta-effect estimates (Hedge's g) were computed using data from 23 studies. Results indicate beneficial effects following training for mindfulness (g = 0.45, p < .001) and stress (g = 0.56, p < .001), anxiety (g = 0.62, p < .001) and psychological distress (g = 0.69, p < .001), and for well-being (g = 0.46, p = .002) and sleep (g = 0.26, p = .003). No conclusions could be drawn from pooled data for burnout due to ambivalence in results, for depression due to publication bias, or for work performance due to insuf",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:30714811
+SPB-0290,10.2519/jospt.2017.7096,The Effectiveness of Trigger Point Dry Needling for Musculoskeletal Conditions by Physical Therapists: A Systematic Review and Meta-analysis.,"Gattie Eric, Cleland Joshua A, Snodgrass Suzanne",2017,The Journal of orthopaedic and sports physical therapy,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Study Design Systematic review and meta-analysis. Background An increasing number of physical therapists in the United States and throughout the world are using dry needling to treat musculoskeletal pain. Objective To examine the short- and long-term effectiveness of dry needling delivered by a physical therapist for any musculoskeletal pain condition. Methods Electronic databases were searched. Eligible randomized controlled trials included those with human subjects who had musculoskeletal conditions that were treated with dry needling performed by a physical therapist, compared with a control or other intervention. The overall quality of the evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation. Results The initial search returned 218 articles. After screening, 13 were included. Physiotherapy Evidence Database quality scale scores ranged from 4 to 9 (out of a maximum score of 10), with a median score of 7. Eight meta-analyses were performed",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:28158962
+SPB-0291,10.1038/s41440-023-01467-9,Effects of aerobic exercise on blood pressure in patients with hypertension: a systematic review and dose-response meta-analysis of randomized trials.,"Jabbarzadeh Ganjeh Bahareh, Zeraattalab-Motlagh Sheida, Jayedi Ahmad, Daneshvar Mojtaba, Gohari Zahra, et al.",2024,Hypertension research : official journal of the Japanese Society of Hypertension,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"We aimed to evaluate the dose-dependent effects of aerobic exercise on systolic (SBP) and diastolic blood pressure (DBP) and haemodynamic factors in adults with hypertension. PubMed, Scopus, and Web of Science were searched to April 2022 for randomized trials of aerobic exercise in adults with hypertension. We conducted a random-effects meta-analysis to estimate mean differences (MDs) and 95%CIs for each 30 min/week increase in aerobic exercise. The certainty of evidence was rated using the GRADE approach. The analysis of 34 trials with 1787 participants indicated that each 30 min/week aerobic exercise reduced SBP by 1.78 mmHg (95%CI: -2.22 to -1.33; n = 34, GRADE=low), DBP by 1.23 mmHg (95%CI: -1.53 to -0.93; n = 34, GRADE=moderate), resting heart rate (MD = -1.08 bpm, 95%CI: -1.46 to -0.71; n = 23, GRADE=low), and mean arterial pressure (MD = -1.37 mmHg, 95%CI: -1.80 to -0.93; n = 9, GRADE = low). A nonlinear dose-dependent decrement was seen on SBP and DBP, with the greatest decreme",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:37872373
+SPB-0292,10.3389/fimmu.2023.1143548,Probiotics fortify intestinal barrier function: a systematic review and meta-analysis of randomized trials.,"Zheng Yanfei, Zhang Zengliang, Tang Ping, Wu Yuqi, Zhang Anqi, et al.",2023,Frontiers in immunology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Probiotics play a vital role in treating immune and inflammatory diseases by improving intestinal barrier function; however, a comprehensive evaluation is missing. The present study aimed to explore the impact of probiotics on the intestinal barrier and related immune function, inflammation, and microbiota composition. A systematic review and meta-analyses were conducted. Four major databases (PubMed, Science Citation Index Expanded, CENTRAL, and Embase) were thoroughly searched. Weighted mean differences were calculated for continuous outcomes with corresponding 95% confidence intervals (CIs), heterogeneity among studies was evaluated utilizing I2 statistic (Chi-Square test), and data were pooled using random effects meta-analyses. Meta-analysis of data from a total of 26 RCTs (n = 1891) indicated that probiotics significantly improved gut barrier function measured by levels of TER (MD, 5.27, 95% CI, 3.82 to 6.72, P < 0.00001), serum zonulin (SMD, -1.58, 95% CI, -2.49 to -0.66, P = 0.",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:37168869
+SPB-0293,10.1016/j.ijnurstu.2021.103976,Repositioning for pressure injury prevention in adults: An abridged Cochrane systematic review and meta-analysis.,"Gillespie Brigid M, Walker Rachel M, Latimer Sharon L, Thalib Lukman, Whitty Jennifer A, et al.",2021,International journal of nursing studies,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"A pressure injury is an area of localised damage to the skin and underlying tissues. Patient repositioning is an important prevention strategy, as those with limited mobility are at increased risk of developing pressure injury. To assess the clinical and cost-effectiveness of repositioning schedules on the prevention of pressure injury in adults. Systematic review and meta-analysis. The Cochrane Wounds Specialised Register; the Cochrane Central Register of Controlled Trials; MEDLINE (Ovid); Embase (Ovid) and Cumulative Index of Nursing and Allied Health Literature Plus (EBSCO) were searched in February 2019. No restrictions were applied to language or date of publication. Studies were eligible if they were randomised controlled trials including cluster trials, published or unpublished, and undertaken in any healthcare setting that assessed the clinical and/or cost effectiveness of repositioning schedules for prevention of pressure injury in adults. Methodological quality of the studies",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:34090235
+SPB-0294,10.1177/03331024231159366,Evaluating the efficacy of CGRP mAbs and gepants for the preventive treatment of migraine: A systematic review and network meta-analysis of phase 3 randomised controlled trials.,"Haghdoost Faraidoon, Puledda Francesca, Garcia-Azorin David, Huessler Eva-Maria, Messina Roberta, et al.",2023,Cephalalgia : an international journal of headache,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Several novel treatments targeting the calcitonin gene-related peptide pathway have been developed for migraine. We evaluated the efficacy of these medications, including atogepant, rimegepant, erenumab, eptinezumab, fremanezumab, and galcanezumab, for the prevention of migraine via network meta-analysis. Databases, including MEDLINE via PubMed, EMBASE, and Cochrane central, were systematically reviewed, and all eligible phase 3 randomised controlled trials were included. Nineteen studies (n = 14,584 participants) were included. Studies included episodic (n = 11) and chronic (n = 4) migraine or both (n = 4). All interventions, except for eptinzumab 30 mg, significantly reduced mean monthly migraine days compared to placebo. All medications had a higher ≥50% responder rate than placebo and results were statistically significant in those with the subcutaneous or intravenous route of administrations, but not with the oral one. All medications significantly reduced mean monthly headache da",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:36855951
+SPB-0295,10.1177/2047487317739978,Psychological interventions for coronary heart disease: Cochrane systematic review and meta-analysis.,"Richards Suzanne H, Anderson Lindsey, Jenkinson Caroline E, Whalley Ben, Rees Karen, et al.",2018,European journal of preventive cardiology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Background Although psychological interventions are recommended for the management of coronary heart disease (CHD), there remains considerable uncertainty regarding their effectiveness. Design Systematic review and meta-analysis of randomised controlled trials (RCTs) of psychological interventions for CHD. Methods The Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, CINAHL and PsycINFO were searched to April 2016. Retrieved papers, systematic reviews and trial registries were hand-searched. We included RCTs with at least 6 months of follow-up, comparing the direct effects of psychological interventions to usual care for patients following myocardial infarction or revascularisation or with a diagnosis of angina pectoris or CHD defined by angiography. Two authors screened titles for inclusion, extracted data and assessed risk of bias. Studies were pooled using random effects meta-analysis and meta-regression was used to explore study-level predictors. Results Thirty-five ",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:29212370
+SPB-0296,10.1002/14651858.CD001751.pub3,Nonsteroidal anti-inflammatory drugs for dysmenorrhoea.,"Marjoribanks Jane, Ayeleke Reuben Olugbenga, Farquhar Cindy, Proctor Michelle",2015,The Cochrane database of systematic reviews,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Dysmenorrhoea is a common gynaecological problem consisting of painful cramps accompanying menstruation, which in the absence of any underlying abnormality is known as primary dysmenorrhoea. Research has shown that women with dysmenorrhoea have high levels of prostaglandins, hormones known to cause cramping abdominal pain. Nonsteroidal anti-inflammatory drugs (NSAIDs) are drugs that act by blocking prostaglandin production. They inhibit the action of cyclooxygenase (COX), an enzyme responsible for the formation of prostaglandins. The COX enzyme exists in two forms, COX-1 and COX-2. Traditional NSAIDs are considered 'non-selective' because they inhibit both COX-1 and COX-2 enzymes. More selective NSAIDs that solely target COX-2 enzymes (COX-2-specific inhibitors) were launched in 1999 with the aim of reducing side effects commonly reported in association with NSAIDs, such as indigestion, headaches and drowsiness. To determine the effectiveness and safety of NSAIDs in the treatment of pr",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:26224322
+SPB-0297,10.1080/16506073.2018.1560358,Psychological and pharmacological treatments for generalized anxiety disorder (GAD): a meta-analysis of randomized controlled trials.,"Carl Emily, Witcraft Sara M, Kauffman Brooke Y, Gillespie Eilis M, Becker Eni S, et al.",2020,Cognitive behaviour therapy,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"The purpose of this meta-analysis was to provide updated pooled effect sizes of evidence-based psychotherapies and medications for generalized anxiety disorder (GAD) and to investigate potential moderators of outcomes. Seventy-nine randomized controlled trials (RCT) including 11,002 participants with a diagnosis of GAD were included in a meta-analysis that tested the efficacy of psychotherapies or medications for GAD. Psychotherapy showed a medium to large effect size (g = 0.76) and medication showed a small effect size (g = 0.38) on GAD outcomes. Psychotherapy also showed a medium effect on depression outcomes (g = 0.64) as did medications (g = 0.59). Younger age was associated with a larger effect size for psychotherapy (p < 0.05). There was evidence of publication bias in psychotherapy studies. This analysis found a medium to large effect for empirically supported psychotherapy interventions on GAD outcomes and a small effect for medications on GAD outcomes. Both groups showed a med",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:30760112
+SPB-0298,10.3390/nu8080483,Effect of Probiotics on Depression: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.,"Huang Ruixue, Wang Ke, Hu Jianan",2016,Nutrients,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"It has been reported that gut probiotics play a major role in the bidirectional communication between the gut and the brain. Probiotics may be essential to people with depression, which remains a global health challenge, as depression is a metabolic brain disorder. However, the efficacy of probiotics for depression is controversial. This study aimed to systematically review the existing evidence on the effect of probiotics-based interventions on depression. Randomized, controlled trials, identified through screening multiple databases and grey literature, were included in the meta-analysis. The meta-analysis was performed using Review Manager 5.3 software using a fixed-effects model. The meta-analysis showed that probiotics significantly decreased the depression scale score (MD (depressive disorder) = -0.30, 95% CI (-0.51--0.09), p = 0.005) in the subjects. Probiotics had an effect on both the healthy population (MD = -0.25, 95% CI (-0.47--0.03), p = 0.03) and patients with major depre",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:27509521
+SPB-0299,10.1016/j.jocn.2021.08.009,Effects of cognitive motor dual-task training on stroke patients: A RCT-based meta-analysis.,"Zhou Qiang, Yang Hongchang, Zhou Quanfu, Pan Hongyao",2021,Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Based on a randomized controlled trial (RCT), this meta-analysis aimed to comprehensively analyze the effects of cognitive motor dual-task training (CMDT) on stroke patients. The electronic databases PubMed, Embase, and the Cochrane Library were searched for papers on the influence of CMDT on stroke patients. Weighted mean difference (WMD) and 95% confidence interval (95% CI) were used as effect sizes. Cochran's Q and I<sup>2</sup> tests were performed for heterogeneity. Thirteen articles involving 326 patients were included in the study. The meta-analysis showed that CMDT significantly improved the walking balance of patients with stroke (P = 0.01). In addition, CMDT significantly improved the gait ability of patients with stroke (P < 0.0001). Furthermore, CMDT had a significant effect on the improvement of upper limb ability in patients with stroke (P < 0.00001). CMDT could significantly improve balance ability, gait, and upper limb function in patients with chronic stroke, which is ",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:34509248
+SPB-0300,10.3390/nu14030679,Effect of Magnesium Supplementation on Inflammatory Parameters: A Meta-Analysis of Randomized Controlled Trials.,"Veronese Nicola, Pizzol Damiano, Smith Lee, Dominguez Ligia J, Barbagallo Mario",2022,Nutrients,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Magnesium (Mg) may have several beneficial effects on human health outcomes. One hypothesized mechanism eliciting such effects is the action of Mg on serum inflammatory parameters. However, studies on this topic to date have several important limitations. Therefore, the present systematic review and meta-analysis aimed to summarize the current state of the art of all randomized control trials (RCTs) investigating the effects of Mg supplementation versus placebo on serum parameters of inflammation. We searched several databases until 23 November 2021 for RCTs. Eligible studies were RCTs investigating the effect of oral Mg supplementation vs. placebo and having serum inflammatory markers as an outcome. Among 2484 papers initially screened, 17 randomized controlled trials (889 participants; mean age: 46 years; females: 62.5%) were included. Generally, a low risk of bias was present. In meta-analysis, Mg supplementation significantly decreased serum C reactive protein (CRP) and increased n",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:35277037
+SPB-0301,10.1161/HYPERTENSIONAHA.116.07664,Effects of Magnesium Supplementation on Blood Pressure: A Meta-Analysis of Randomized Double-Blind Placebo-Controlled Trials.,"Zhang Xi, Li Yufeng, Del Gobbo Liana C, Rosanoff Andrea, Wang Jiawei, et al.",2016,"Hypertension (Dallas, Tex. : 1979)",pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"The antihypertensive effect of magnesium (Mg) supplementation remains controversial. We aimed to quantify the effect of oral Mg supplementation on blood pressure (BP) by synthesizing available evidence from randomized, double-blind, placebo-controlled trials. We searched trials of Mg supplementation on normotensive and hypertensive adults published up to February 1, 2016 from MEDLINE and EMBASE databases; 34 trials involving 2028 participants were eligible for this meta-analysis. Weighted mean differences of changes in BP and serum Mg were calculated by random-effects meta-analysis. Mg supplementation at a median dose of 368 mg/d for a median duration of 3 months significantly reduced systolic BP by 2.00 mm Hg (95% confidence interval, 0.43-3.58) and diastolic BP by 1.78 mm Hg (95% confidence interval, 0.73-2.82); these reductions were accompanied by 0.05 mmol/L (95% confidence interval, 0.03, 0.07) elevation of serum Mg compared with placebo. Using a restricted cubic spline curve, we ",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:27402922
+SPB-0302,10.1016/j.neurom.2023.06.002,Transcutaneous Electrical Stimulation for Neurogenic Bladder After Spinal Cord Injury: A Systematic Review and Meta-Analysis.,"Jiang Yangyang, Li Xiang, Guo Suhui, Wei Zhengshu, Xu Senming, et al.",2024,Neuromodulation : journal of the International Neuromodulation Society,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"This review aims to assess the efficacy of transcutaneous electrical nerve stimulation (TENS) for neurogenic bladder after spinal cord injury (SCI). A systematic search was conducted of seven electronic data bases from inception to Dec 31, 2022, to identify randomized controlled trials that studied TENS for neurogenic bladder after SCI. The primary outcomes were maximum cystometric capacity (MCC) and residual urine volume (RUV). Secondary outcomes included maximum detrusor pressure, flow rate, and bladder diary. Random effects models were used in all analyses. Eleven trials involving 881 participants were included. Meta-analysis showed that TENS in addition to conventional treatment had larger MCC (mean difference [MD] 50.55 ml, 95% CI 27.81-73.29, p＜0.0001) and lower RUV (MD -22.96 ml, 95% CI -33.45 to -12.47, p＜0.0001) than did conventional treatment only. Compared with magnetic stimulation, no differences were observed with TENS for MCC (MD -14.49 ml, 95% CI -48.97 to 19.98, p = 0.4",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:37642626
+SPB-0303,10.1016/j.jad.2023.05.048,The efficacy and safety of transcutaneous auricular vagus nerve stimulation in the treatment of depressive disorder: A systematic review and meta-analysis of randomized controlled trials.,"Tan Chaoren, Qiao Meng, Ma Yue, Luo Yi, Fang Jiliang, et al.",2023,Journal of affective disorders,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Transcutaneous auricular vagus nerve stimulation (taVNS) is used for treating depression but the efficacy and safety have not been well assessed. This study was conducted to evaluate the efficacy and safety of taVNS in depression. The retrieval databases included English databases of PubMed, Web of Science, Embase, the Cochrane Library and PsycINFO, and Chinese databases of CNKI, Wanfang, VIP and Sino Med, and the retrieval period was from their inception to November 10, 2022. The clinical trial registers (ClinicalTrials.gov and Chinese Clinical Trial Registry) were also searched. Standardized mean difference and the risk ratio were used as the effect indicator and the effect size was represented by the 95 % confidence interval. Revised Cochrane risk-of-bias tool for randomized trials and the Grades of Recommendation, Assessment, Development and Evaluation system were used to assess the risk of bias and quality of evidence respectively. Totally, 12 studies of 838 participants were incl",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:37230264
+SPB-0304,10.1007/s00455-023-10626-6,Neuromuscular Electrical Stimulation for Post-Stroke Dysphagia Treatment: A Systemic Evaluation and Meta-Analysis of Randomized Controlled Trials.,"Wang Zhenni, Xiao Zihao, Shen Qin, Zhao Na, Zhang Weiming",2024,Dysphagia,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Neuromuscular electrical stimulation (NMES) is a novel treatment method that stimulates patients' swallowing functions. This systemic review was designed to evaluate the impact of NMES on dysphagia in stroke patients. Databases including PubMed, Embase, Web of Science, and Cochrane Library were searched from the date of establishment to January 28th, 2022. Two investigators identified all included studies and compared the swallowing function after NMES treatment with traditional therapy (TT). The Cochrane risk bias assessment tool was utilized to analyze the quality of included studies. Research outcomes included Swallowing Quality of Life (SWAL-QoL), Penetration-Aspiration Scale (PAS), Functional Oral Intake Scale (FOIS), Dysphagia Outcomes and Severity Scale (DOSS), the Repeat Salivary Swallowing Test (RSST), and Water Swallowing Test (WST). We extracted the mean and standard deviation of specific outcomes at the baseline level and after the treatment in both NMES and TT groups for s",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:37914887
+SPB-0305,10.1016/j.nrl.2017.07.009,Effectiveness of omega-3 fatty acid supplementation in patients with Alzheimer disease: A systematic review and meta-analysis.,"Araya-Quintanilla F, Gutiérrez-Espinoza H, Sánchez-Montoya U, Muñoz-Yañez M J, Baeza-Vergara A, et al.",2020,Neurologia,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Alzheimer disease (AD) is a neurodegenerative disease characterised by progressive dementia associated with global cognitive dysfunction. We conducted a systematic review and meta-analysis of clinical trials evaluating omega-3 supplementation in patients with AD. To determine if there is scientific evidence of the effectiveness of omega-3 supplementation in improving cognitive function in patients with AD. We included only randomised controlled trials (RCTs) from the following databases: Medline, Cochrane Central, Cinahl, and LILACS. An electronic search was also conducted using Google Scholar. Six articles met the eligibility criteria. The risk of bias was assessed following the Cochrane method. There is no consistent evidence to support the effectiveness of omega-3 supplementation in improving cognitive function in AD patients in the short and medium term.",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:28986068
+SPB-0306,10.3389/fimmu.2023.1024120,Efficacy and safety of dietary polyphenols in rheumatoid arthritis: A systematic review and meta-analysis of 47 randomized controlled trials.,"Long Zhiyong, Xiang Wang, He Qi, Xiao Wei, Wei Huagen, et al.",2023,Frontiers in immunology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"To evaluate safety and efficacy of dietary polyphenols in the treatment of rheumatoid arthritis (RA). CNKI, Pubmed, Cochrane library, Embase were searched to collect randomized controlled trials (RCTs) of dietary polyphenols in the treatment of RA. The databases were searched from the time of their establishment to November 8nd, 2022. After 2 reviewers independently screened the literature, extracted data, and assessed the risk of bias of the included studies, Meta-analysis was performed using RevMan5.4 software. A total of 49 records (47 RCTs) were finally included, involving 3852 participants and 15 types of dietary polyphenols (Cinnamon extract, Cranberry extract, Crocus sativus L. extract, Curcumin, Garlic extract, Ginger extract, Hesperidin, Olive oil, Pomegranate extract, Puerarin, Quercetin, Resveratrol, Sesamin, Tea polyphenols, Total glucosides of paeony). Pomegranate extract, Resveratrol, Garlic extract, Puerarin, Hesperidin, Ginger extract, Cinnamon extract, Sesamin only inv",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:37033930
+SPB-0307,10.3390/nu14142831,Inositol Nutritional Supplementation for the Prevention of Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.,"Wei Jingshu, Yan Jie, Yang Huixia",2022,Nutrients,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"This study was aimed at assessing the efficacy and safety of inositol nutritional supplementation during pregnancy for the prevention of GDM. PubMed, Embase, MEDLINE, and Cochrane library were systematically searched for randomized controlled trails (RCTs) in this field until May 2022. Primary outcomes were the incidence for GDM and plasma glucose levels by oral glucose tolerance test (OGTT). Pooled results were expressed as relative risk (RR) or mean difference (MD) with a 95% confidence interval (95% CI). Seven RCTs with 1321 participants were included in this study. Compared with the control group, 4 g myo-inositol (MI) supplementation per day significantly decreased the incidence of GDM (RR = 0.30, 95% CI (0.18, 0.49), p < 0.00001). It significantly decreased the plasma glucose levels of OGTT regarding fasting-glucose OGTT (MD = −4.20, 95% CI (−5.87, −2.54), p < 0.00001), 1-h OGTT (MD = −8.75, 95% CI (−12.42, −5.08), p < 0.00001), and 2-h OGTT (MD = −8.59, 95% CI (−11.81, −5.83), p",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:35889788
+SPB-0308,10.1016/j.bja.2022.12.001,Effect of perioperative benzodiazepine use on intraoperative awareness and postoperative delirium: a systematic review and meta-analysis of randomised controlled trials and observational studies.,"Wang Eugene, Belley-Côté Emilie P, Young Jack, He Henry, Saud Haris, et al.",2023,British journal of anaesthesia,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Benzodiazepine use is associated with delirium, and guidelines recommend avoiding them in older and critically ill patients. Their perioperative use remains common because of perceived benefits. We searched CENTRAL, MEDLINE, CINAHL, PsycInfo, and Web of Science from inception to June 2021. Pairs of reviewers identified randomised controlled trials and prospective observational studies comparing perioperative use of benzodiazepines with other agents or placebo in patients undergoing surgery. Two reviewers independently abstracted data, which we combined using a random-effects model. Our primary outcomes were delirium, intraoperative awareness, and mortality. We included 34 randomised controlled trials (n=4354) and nine observational studies (n=3309). Observational studies were considered separately. Perioperative benzodiazepines did not increase the risk of delirium (n=1352; risk ratio [RR] 1.43; 95% confidence interval [CI]: 0.9-2.27; I<sup>2</sup>=72%; P=0.13; very low-quality evidenc",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:36621439
+SPB-0309,10.1016/S2468-1253(17)30054-7,Restrictive versus liberal blood transfusion for gastrointestinal bleeding: a systematic review and meta-analysis of randomised controlled trials.,"Odutayo Ayodele, Desborough Michael J R, Trivella Marialena, Stanley Adrian J, Dorée Carolyn, et al.",2017,The lancet. Gastroenterology & hepatology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Acute upper gastrointestinal bleeding is a leading indication for red blood cell (RBC) transfusion worldwide, although optimal thresholds for transfusion are debated. We searched MEDLINE, Embase, CENTRAL, CINAHL, and the Transfusion Evidence Library from inception to Oct 20, 2016, for randomised controlled trials comparing restrictive and liberal RBC transfusion strategies for acute upper gastrointestinal bleeding. Main outcomes were mortality, rebleeding, ischaemic events, and mean RBC transfusion. We computed pooled estimates for each outcome by random effects meta-analysis, and individual participant data for a cluster randomised trial were re-analysed to facilitate meta-analysis. We compared treatment effects between patient subgroups, including patients with liver cirrhosis, patients with non-variceal upper gastrointestinal bleeding, and patients with ischaemic heart disease at baseline. We included four published and one unpublished randomised controlled trial, totalling 1965 par",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:28397699
+SPB-0310,10.1016/j.physio.2022.09.004,Prevention of low back and pelvic girdle pain during pregnancy: a systematic review and meta-analysis of randomised controlled trials with GRADE recommendations.,"Santos Flávia F, Lourenço Bianca M, Souza Mateus B, Maia Laísa B, Oliveira Vinicius C, et al.",2023,Physiotherapy,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Low back (LBP) and pelvic girdle pain (PGP) during pregnancy are related to high direct and indirect costs. It is important to clarify evidence regarding interventions to manage and prevent these conditions. Investigate the efficacy and acceptability of the interventions to prevent LBP and PGP during pregnancy. Searches were conducted up to January 6th, 2021 in the MEDLINE, PEDro, Cochrane Library, SPORTDiscus, CINAHL, AMED, Embase and PsycInfo databases STUDY ELIGIBILITY CRITERIA: (1) Pregnant women without LBP and/or PGP; (2) any prevention strategy on incidence of LBP and PGP and sick leave; (3) comparison to control; (4) quasi and randomised controlled trial. Two reviewers performed screening, data extraction and methodological quality assessments. Meta-analysis was performed and Relative Risks (RRs) and 95% confidence intervals (CIs) were reported. Six randomised controlled trials involving 2231 participants were included in the review. Evidence of moderate quality was found that ",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:36288631
+SPB-0311,10.1111/jocn.16397,Effect of virtual reality technology as intervention for people with kinesiophobia: A meta-analysis of randomised controlled trials.,"Wang Shanshan, Sun Jiao, Yin Xin, Li Hongyan",2023,Journal of clinical nursing,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"To explore the effectiveness of Virtual Reality Technology in reducing kinesiophobia in people. Kinesiophobia is an important psychosocial factor affecting the pain experience and has a significant negative impact on rehabilitation. Virtual reality technology has been widely used in the treatment of phobias, mental disorders and anxiety disorders. However, the effect of virtual reality technology on people with kinesiophobia has been reported with inconsistent results. A meta-analysis of randomised controlled trials. This study systematically searched PubMed, Web of Science, PsycINFO, CINAHL, Embase, Cochrane Library, Medline, Scopus and four Chinese databases. The standardised mean difference (SMD) was calculated using random-effects models, and the Cochrane Collaboration's tool was used to assess the risk of bias in each study. The PRISMA 2020 checklist provided by the EQUATOR network was used. Eleven randomised controlled trials involving a total of 488 subjects were included. Meta-",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:35692077
+SPB-0312,10.1007/s40265-021-01661-4,Third-Generation Antiseizure Medications for Adjunctive Treatment of Focal-Onset Seizures in Adults: A Systematic Review and Network Meta-analysis.,"Lattanzi Simona, Trinka Eugen, Zaccara Gaetano, Striano Pasquale, Russo Emilio, et al.",2022,Drugs,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Brivaracetam (BRV), cenobamate (CNB), eslicarbazepine acetate (ESL), lacosamide (LCM) and perampanel (PER) are antiseizure medications (ASMs) approved for adjunctive treatment of focal-onset seizures. So far, no randomised controlled trial directly compared the efficacy and safety of these drugs. We estimated the comparative efficacy and safety of these ASMs for the treatment of focal-onset seizures in adults with epilepsy using a network meta-analysis (NMA). We systematically searched (June week 4, 2021) MEDLINE (accessed by PubMed), the Cochrane Central Register of Controlled Trials (CENTRAL), and the US National Institutes of Health Clinical Trials Registry ( http://www.clinicaltrials.gov ). There were no date limitations or language restrictions. Randomised, double-blinded, controlled, parallel-group, add-on studies that compared oral BRV, CNB, ESL, LCM, and PER versus any comparator over maintenance periods of at least 12 weeks and included adult patients with focal seizures uncon",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:35061214
+SPB-0313,10.1007/s40279-023-01826-z,"Injury Rates, Mechanisms, Risk Factors and Prevention Strategies in Youth Rugby Union: What's All the Ruck-Us About? A Systematic Review and Meta-analysis.","West Stephen W, Shill Isla J, Bailey Stuart, Syrydiuk Reid A, Hayden K Alix, et al.",2023,"Sports medicine (Auckland, N.Z.)",pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Rugby Union is a collision team sport played globally. Despite this, significant concerns have been raised regarding the sport's safety, particularly in youth players. Given this, a review of injury rates, risk factors and prevention strategies is required across different youth age groups as well as in males and females. The objective of this systematic review (SR) and meta-analysis was to investigate injury and concussion rates, risk factors and primary prevention strategies in youth rugby. To be included, studies were required to report either rates, risk factors or prevention strategies in youth rugby and to have a randomised controlled trial, quasi-experimental, cohort, case control, or ecological study design. Exclusion criteria included non-peer-reviewed grey literature, conference abstracts, case studies, previous systematic reviews and studies not written in English. Nine databases were searched. The full search strategy and list of sources are available and pre-registered on ",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:37191819
+SPB-0314,10.1002/smi.2857,Contemplative interventions and employee distress: A meta-analysis.,"Slemp Gavin R, Jach Hayley K, Chia Austin, Loton Daniel J, Kern Margaret L",2019,Stress and health : journal of the International Society for the Investigation of Stress,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Mindfulness, meditation, and other practices that form contemplative interventions are increasingly offered in workplaces to support employee mental health. Studies have reported benefits across various populations, yet researchers have expressed concerns that adoption of such interventions has outpaced scientific evidence. We reappraise the extant literature by meta-analytically testing the efficacy of contemplative interventions in reducing psychological distress in employees (meta-analysed set: k = 119; N = 6,044). Complementing other reviews, we also examine a range of moderators and the impact of biases that could artificially inflate effect sizes. Results suggested interventions were generally effective in reducing employee distress, yielding small to moderate effects that were sustained at last follow-up. Effects were moderated by the type of contemplative intervention offered and the type of control group utilized. We also found evidence of publication bias, which is likely inf",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:30698328
+SPB-0315,10.12659/MSM.909995,Efficacy and Safety of Acupuncture for Essential Hypertension: A Meta-Analysis.,"Chen Hao, Shen Fei-Er, Tan Xiao-Dong, Jiang Wen-Bo, Gu Yi-Huang",2018,Medical science monitor : international medical journal of experimental and clinical research,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"BACKGROUND The aim of this study was to assess the efficacy and safety of acupuncture therapy for patients with hypertension. MATERIAL AND METHODS We searched PubMed, Embase, the Cochrane Library, the Chinese Biomedical Literature Database, the Chinese National Knowledge Infrastructure, and the Wan-fang Data Database from inception through 29 April 2017. Randomized controlled trials investigating acupuncture therapy for hypertension were included. Review Manager 5.3 software was used for the data analysis. RESULTS A total of 30 RCTs involving 2107 patients were included. The overall methodological quality of the included studies was low. Pooled results demonstrate that acupuncture plus anti-hypertensive drugs is better than anti-hypertensive drugs alone at reducing systolic and diastolic blood pressure (SBP and DBP). The same result was observed for pooled data from experiments that compared acupuncture plus medication to sham acupuncture plus medication at reducing SBP and DBP. Howeve",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:29735972
+SPB-0316,10.1016/S2213-2600(16)00057-6,Association between driving pressure and development of postoperative pulmonary complications in patients undergoing mechanical ventilation for general anaesthesia: a meta-analysis of individual patient data.,"Neto Ary Serpa, Hemmes Sabrine N T, Barbas Carmen S V, Beiderlinden Martin, Fernandez-Bustamante Ana, et al.",2016,The Lancet. Respiratory medicine,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Protective mechanical ventilation strategies using low tidal volume or high levels of positive end-expiratory pressure (PEEP) improve outcomes for patients who have had surgery. The role of the driving pressure, which is the difference between the plateau pressure and the level of positive end-expiratory pressure is not known. We investigated the association of tidal volume, the level of PEEP, and driving pressure during intraoperative ventilation with the development of postoperative pulmonary complications. We did a meta-analysis of individual patient data from randomised controlled trials of protective ventilation during general anesthaesia for surgery published up to July 30, 2015. The main outcome was development of postoperative pulmonary complications (postoperative lung injury, pulmonary infection, or barotrauma). We included data from 17 randomised controlled trials, including 2250 patients. Multivariate analysis suggested that driving pressure was associated with the developm",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:26947624
+SPB-0317,10.1002/alr.21746,Placebo-controlled assessment of somnolence effect of cetirizine: a meta-analysis.,"Du Qiong, Zhou Yingchun",2016,International forum of allergy & rhinology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"It has been found that the most common adverse reaction which occurs more frequently on cetirizine than on placebo is somnolence. However, the somnolence rate varied widely among different studies. The objective of this study was to assess the somnolence effect of cetirizine 10 mg daily compared to placebo in patients aged 6 years and older using meta-analysis and explore the sources of heterogeneity among different studies. Databases were searched for randomized controlled trials (RCTs) of cetirizine published before 2015. Overall risk differences (RDs) were determined by meta-analyses of 13 trials using the DerSimonian and Laird (D&L) method based on fixed-effects and random-effect models, respectively. The Q statistic, H statistic, and I(2) were calculated for heterogeneity analysis. Subgroup analysis, Galbraith plot, sensitivity analysis, and meta-regression were also performed to explore the sources of heterogeneity. Various analyses showed that heterogeneity existed among the 13 ",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:26990040
+SPB-0318,10.1016/j.jdent.2019.07.008,Network meta-analysis on the effect of desensitizing toothpastes on dentine hypersensitivity.,"Hu Meng-Long, Zheng Gang, Lin Hong, Yang Meng, Zhang You-Dong, et al.",2019,Journal of dentistry,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"This network meta-analysis compares different desensitizing toothpastes and placebo in terms of their effects on dentine hypersensitivity (DH) at 2, 4, and 8 weeks. A systematic electronic literature search of four databases, and a manual search, were performed to identify randomized controlled trials (RCTs) on different desensitizing toothpastes for the treatment of DH. Pair-wise and network meta-analyses were performed to analyze the desensitization effect at 2, 4, and 8 weeks. The risk of bias was assessed based on the Cochrane guidelines and funnel plots. Statistical heterogeneity, inconsistencies, and ranking probability were also evaluated. A total of 30 RCTs were included in the network meta-analysis, which included eight desensitizing toothpastes. There was no significant difference in the effect among calcium sodium phosphosilicate-containing (CSPS), potassium-containing (K) and strontium-containing (Sr) toothpastes. In addition, there was no significant difference between flu",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:31325467
+SPB-0319,10.1017/S1041610218002168,A systematic review and meta-analysis on the effect of reminiscence therapy for people with dementia.,"Park Kyongok, Lee Seonhye, Yang JeongEun, Song Taekwon, Hong Gwi-Ryung Son",2019,International psychogeriatrics,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"The main objective of this study was to conduct a meta-analysis to identify the effects of reminiscence therapy in people with dementia (PWD). A systematic search of randomized controlled trials (RCTs) was conducted using bibliographic databases. A total of 157 original published studies were identified in the search, and 24 complete articles were included in the final review to check for the level of evidence. Two of the study authors independently assessed the quality of the included studies using the ""Risk of Bias"" (ROB) tool developed by the Cochrane Collaboration. Depression, quality of life, and behavioral and psychological symptoms of dementia (BPSD) were selected to measure the effect of reminiscence therapy. To determine the effects of reminiscence therapy on these variables, each individual study was analyzed using Comprehensive Meta-Analysis Software® (Biostat, Englewood, NJ, USA). The overall effect size was presented using standardized mean differences (SMDs) and 95% confi",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:30712519
+SPB-0320,10.1007/s10151-022-02629-6,Early vs. standard reversal ileostomy: a systematic review and meta-analysis.,"O'Sullivan N J, Temperley H C, Nugent T S, Low E Z, Kavanagh D O, et al.",2022,Techniques in coloproctology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Formation of a defunctioning loop ileostomy is common after mid and low rectal resection. Historically, they were reversed between 3 and 6 months after initial resection. Recently, earlier closure (< 14 days) has been suggested by some current randomised controlled trials. The aim of this study was to investigate the effect of early stoma closure on surgical and patient outcomes. A systematic review of the current randomised controlled trial literature comparing early and standard ileostomy closure after rectal surgery was performed. Specifically, we examined surgical outcomes including; morbidity, mortality and quality of life. Six studies met the predefined criteria and were included in our analysis. 275 patients underwent early stoma closure compared with 259 patients having standard closure. Overall morbidity was similar between both groups (25.5% vs. 21.6%) (OR, 1.47; 95% CI 0.75-2.87). However, there tended to be more reoperations (8.4 vs. 4.2%) (OR, 2.02, 95% CI 0.99-4.14) and s",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:35596904
+SPB-0321,10.1136/bmjopen-2018-022879,Efficacy and safety of the pulsed electromagnetic field in osteoarthritis: a meta-analysis.,"Wu Ziying, Ding Xiang, Lei Guanghua, Zeng Chao, Wei Jie, et al.",2018,BMJ open,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"To investigate the efficacy and safety of the pulsed electromagnetic field (PEMF) therapy in treating osteoarthritis (OA). Meta-analysis. PubMed, Embase, the Cochrane Library and Web of Science were searched through 13 October 2017. Randomised controlled trials compared the efficacy of PEMF therapy with sham control in patients with OA. Pain, function, adverse effects and characteristics of participants were extracted. RevMan V.5.2 was used to perform statistical analyses. Twelve trials were included, among which ten trials involved knee OA, two involved cervical OA and one involved hand OA. The PEMF group showed more significant pain alleviation than the sham group in knee OA (standardised mean differences (SMD)=-0.54, 95% CI -1.04 to -0.04, p=0.03) and hand OA (SMD=-2.85, 95% CI -3.65 to -2.04, p<0.00001), but not in cervical OA. Similarly, comparing with the sham-control treatment, significant function improvement was observed in the PEMF group in both knee and hand OA patients (SMD",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:30552258
+SPB-0322,10.1007/s00345-023-04673-9,Systematic review and meta-analysis of the efficacy of exercise intervention in kidney transplant recipients.,"Zhang Dongxu, Yu Liqian, Xia Bowen, Zhang Xin, Liang Pu, et al.",2023,World journal of urology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"There is uncertainty about the beneficial effects of exercise intervention for kidney transplant recipients. The purpose of our meta-analysis is to estimate the efficacy of exercise intervention in kidney transplant recipients. A database search according to the PICOS framework was performed for all published randomized, double-blind, placebo-controlled trials (RCTs) about exercise intervention for kidney transplant recipients. The databases involved include PubMed, Embase, and Cochrane Library. A total of 16 RCTs (involving 827 patients) in compliance with inclusion criteria were included in our study. The results demonstrated that adequate exercise intervention improved statistically in creatinine clearance [mean difference (MD) =  - 0.29, 95% confidence interval (CI) - 0.46 to - 0.11, p = 0.001], serum urea (MD = - 21.57, 95% CI - 35.84 to - 7.29, p = 0.003), VO<sub>2</sub> peak (MD = 3.20, 95% CI 1.97-4.43, p < 0.00001), high-density lipoprotein-cholesterol (HDL-C) (MD = 0.21, 95% ",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:37882807
+SPB-0323,10.1016/j.ijnurstu.2017.04.005,Oxygen therapy for acute myocardial infarction: A systematic review and meta-analysis.,"Fu Shimin, Lv Xia, Fang Qin, Liu Zhiping",2017,International journal of nursing studies,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Potential benefits or risks of oxygen inhalation for patients with acute myocardial infarction are not fully understood. We performed this study to systematically assess the effectiveness and safety of oxygen therapy for patients with acute myocardial infarction. A systematic review and meta-analysis. We searched randomized controlled trials systematically in PubMed, EMBASE, Web of Science and Cochrane Library up to June 2016. Randomized controlled trials that estimated the effectiveness and safety of oxygen therapy for patients with acute myocardial infarction were identified by two independent reviewers. The primary outcomes were short-term mortality and recurrent rate of myocardial infarction, and the secondary outcomes were arrhythmia incidence and pain incidence. Relative risks (RRs) and 95% confidence intervals (CIs) were used to measure the pooled data. A total of five randomized controlled trials were in accordance with inclusion criteria and were included in this meta-analysis",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:28595112
+SPB-0324,10.3390/nu14020303,Critical Appraisal of Large Vitamin D Randomized Controlled Trials.,"Pilz Stefan, Trummer Christian, Theiler-Schwetz Verena, Grübler Martin R, Verheyen Nicolas D, et al.",2022,Nutrients,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"As a consequence of epidemiological studies showing significant associations of vitamin D deficiency with a variety of adverse extra-skeletal clinical outcomes including cardiovascular diseases, cancer, and mortality, large vitamin D randomized controlled trials (RCTs) have been designed and conducted over the last few years. The vast majority of these trials did not restrict their study populations to individuals with vitamin D deficiency, and some even allowed moderate vitamin D supplementation in the placebo groups. In these RCTs, there were no significant effects on the primary outcomes, including cancer, cardiovascular events, and mortality, but explorative outcome analyses and meta-analyses revealed indications for potential benefits such as reductions in cancer mortality or acute respiratory infections. Importantly, data from RCTs with relatively high doses of vitamin D supplementation did, by the vast majority, not show significant safety issues, except for trials in critically",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:35057483
+SPB-0325,10.1111/jhn.12963,Quality improvement strategies enhance primary care dietetics: A systematic review and meta-analysis.,"Kirkegaard Amy, Ball Lauren, Mitchell Lana, Brickley Bryce, Williams Lauren T",2022,Journal of human nutrition and dietetics : the official journal of the British Dietetic Association,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Quality improvement strategies have been widely applied in health care; however, little is known about their use in primary care dietetics. This review aims to describe and evaluate the effectiveness of quality improvement strategies that seek to improve patient outcomes by enhancing dietetic care compared to standard dietetic care. The study employed a systematic review and meta-analysis design following PRISMA guidelines and included studies up to March 2021. Studies were included if they used a randomised controlled trial (RCT) design to evaluate the effect of a quality improvement strategy applied to care delivered by a dietitian on patient outcomes. A meta-analysis was conducted where there were sufficient studies with homogeneous populations and outcome measures. Twelve RCTs (n = 1604) met the inclusion criteria for review and five studies (n = 511) were eligible for meta-analysis for glycated haemoglobin in patients with type 2 diabetes. The most frequently reported quality impr",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:34725871
+SPB-0326,10.1097/MD.0000000000029767,Efficacy of ginseng supplements on disease-related fatigue: A systematic review and meta-analysis.,"Zhu Jianxun, Xu Xiaoru, Zhang Xin, Zhuo Yue, Chen Shaotao, et al.",2022,Medicine,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Ginseng has been believed to provide energy, physical health, and well-being to patients for hundreds of years. Fatigue is a multidimensional symptom with unknown etiology and varying severity, and lots of patients suffer from fatigue. We search for research of ginseng treatment of disease-related fatigue in adult patients in Pubmed, Embase, Medline, and Cochrane library. Two independent reviewers assessed included studies and met to develop consensus on included studies. And we used Review Manager 5.3 software to evaluate the risk of bias. The present meta-analysis included 12 randomized controlled trial containing 1298 patients. In the fixed-effect meta-analysis of 12 randomized controlled trial, ginseng supplements had a statistically significant efficacy on disease-related fatigue reduction (standardized mean difference = 0.33, 95% confidence interval = 0.44-0.22). The use of ginseng supplements is benefit for patients to reduce disease-related fatigue.",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:35776997
+SPB-0327,10.1136/bmjopen-2018-027953,Cochrane systematic review and meta-analysis of botulinum toxin for the prevention of migraine.,"Herd Clare P, Tomlinson Claire L, Rick Caroline, Scotton William J, Edwards Julie, et al.",2019,BMJ open,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"To assess the effects of botulinum toxin for prevention of migraine in adults. Systematic review and meta-analysis. CENTRAL, MEDLINE, Embase and trial registries. We included randomised controlled trials (RCTs) of botulinum toxin compared with placebo, active treatment or clinically relevant different dose for adults with chronic or episodic migraine, with or without the additional diagnosis of medication overuse headache. Cochrane methods were used to review double-blind RCTs. Twelve week post-treatment time-point data was analysed. Twenty-eight trials (n=4190) were included. Trial quality was mixed. Botulinum toxin treatment resulted in reduced frequency of -2.0 migraine days/month (95% CI -2.8 to -1.1, n=1384) in chronic migraineurs compared with placebo. An improvement was seen in migraine severity, measured on a numerical rating scale 0 to 10 with 10 being maximal pain, of -2.70 cm (95% CI -3.31 to -2.09, n=75) and -4.9 cm (95% CI -6.56 to -3.24, n=32) for chronic and episodic mig",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:31315864
+SPB-0328,10.1136/bmjopen-2017-020584,Legacy effects of statins on cardiovascular and all-cause mortality: a meta-analysis.,"Nayak Agnish, Hayen Andrew, Zhu Lin, McGeechan Kevin, Glasziou Paul, et al.",2018,BMJ open,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"To assess evidence for 'legacy' (post-trial) effects on cardiovascular disease (CVD) mortality and all-cause mortality among adult participants of placebo-controlled randomised controlled trials (RCTs) of statins. Meta-analysis of aggregate data. Placebo-controlled statin RCTS for primary and secondary CVD prevention. Data sources: PubMed, Embase from inception and forward citations of Cholesterol Treatment Trialists' Collaborators RCTs to 16 June 2016. Two independent reviewers identified all statin RCT follow-up reports including ≥1000 participants, and cardiovascular and all-cause mortality. Two independent reviewers extracted data in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Post-trial CVD and all-cause mortality. We included eight trials, with mean post-trial follow-up ranging from 1.6 to 15.1 years, and including 13 781 post-trial deaths (6685 CVD). Direct effects of statins within trials were greater than legacy effects po",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:30287603
+SPB-0329,10.21873/anticanres.13643,Vitamin D and Cardiovascular Disease: An Update.,"Zittermann Armin, Pilz Stefan",2019,Anticancer research,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"In the clinical setting, administration of high daily or bolus doses of vitamin D is often solely based on 25-hydroxyvitamin D [25(OH)D] testing. This review summarizes the evidence of the effect of vitamin D on cardiovascular disease (CVD). Meta-analyses of randomized controlled trials (RCTs) have demonstrated that CVD risk markers, such as lipid parameters, inflammation markers, blood pressure, and arterial stiffness, are largely unaffected by vitamin D supplementation. Similar results have been obtained regarding CVD events and mortality from (meta)-analyses of RCTs, even in subgroups with 25(OH)D concentrations <50 nmol/l. Likewise, Mendelian randomization studies have indicated that the genetic reduction of the 25(OH)D concentration does not increase CVD risk. Some studies do not exclude the possibility of adverse vitamin D effects, such as elevated plasma calcium concentration and an increased CVD risk at a 25(OH)D concentration >125 nmol/l. Based on a conservative benefit-risk m",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:31519560
+SPB-0330,10.1111/psyg.12275,Choto-san versus placebo for patients with dementia: systematic review and meta-analysis.,"Imai Hissei, Takeshima Nozomi, Oda Haruhiko, Chen Peiyao, Sawada Etsuko, et al.",2017,Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Choto-san is a traditional medicine used for hypertension and headaches in Japan and China. Some studies have shown its effectiveness in the treatment of dementia. The present review aimed to assess the effectiveness and acceptability of Choto-san in the treatment of adults with cognitive impairment. We included randomized controlled trials comparing Choto-san with placebo for patients with dementia or mild cognitive impairment. Three randomized controlled trials evaluating 219 participants were included. Two were studies on vascular dementia, and the other was on Alzheimer's dementia. There was no difference between Choto-san and placebo in terms of short-term dichotomous judgement of improvement, but Choto-san was more effective than placebo in terms of short-term improvement of cognitive function as measured by continuous outcomes. Also, dropouts judged it to be acceptable. However, the results were imprecise and/or heterogeneous. The number of participants included in the analysis ",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:28589702
+SPB-0331,10.1007/s00132-018-3604-x,Robot-assisted vs. conventional unicompartmental knee arthroplasty : Systematic review and meta-analysis.,"Fu Jun, Wang Yuning, Li Xiang, Yu Baozhan, Ni Ming, et al.",2018,Der Orthopade,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Numerous advances have been made in prosthesis design, instrumentation and postoperative rehabilitation for unicompartmental knee arthroplasty; however, only 70-86% of patients are satisfied with the functional outcome and revision rates range between 10% and 20%. The primary outcome for this meta-analysis was implantation accuracy of component positioning and tibiofemoral component safe zone. A total of three randomized controlled trials (RCT), three quasi-RCTs and one prospective trial were included in this review. It was found that the use of robotic-assisted systems reduces implantation errors without an increase in adverse events. There are only a few reports about clinical outcome and long-term follow-up and whether the more accurate component positioning results in a better clinical effect or a better long-term survival of the implants is unknown.",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:30051277
+SPB-0332,10.1002/14651858.CD002903.pub3,WITHDRAWN: Electrical cardioversion for atrial fibrillation and flutter.,"Mead Gillian E, Elder Andrew, Flapan Andrew D, Cordina John",2017,The Cochrane database of systematic reviews,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Atrial fibrillation increases stroke risk and adversely affects cardiovascular haemodynamics. Electrical cardioversion may, by restoring sinus rhythm, improve cardiovascular haemodynamics, reduce the risk of stroke, and obviate the need for long-term anticoagulation. To assess the effects of electrical cardioversion of atrial fibrillation or flutter on the risk of thromboembolic events, strokes and mortality (primary outcomes), the rate of cognitive decline, quality of life, the use of anticoagulants and the risk of re-hospitalisation (secondary outcomes) in adults (>18 years). We searched the Cochrane CENTRAL Register of Controlled Trials (1967 to May 2004), MEDLINE (1966 to May 2004), Embase (1980 to May 2004), CINAHL (1982 to May 2004), proceedings of the American College of Cardiology (published in Journal of the American College of Cardiology 1983 to 2003), www.trialscentral.org, www.controlled-trials.com and reference lists of articles. We hand-searched the indexes of the Proceed",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:29140555
+SPB-0333,10.1186/s12891-015-0702-3,A systematic review and meta-analysis regarding the use of corticosteroids in septic arthritis.,Farrow Luke,2015,BMC musculoskeletal disorders,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Chondral damage is one of the major sequelae of septic arthritis; occurring even after prompt treatment of a septic joint. Subsequent loss of joint function can have a significant impact on a patient's quality of life. Corticosteroids are known to have beneficial effects on the rate and extent cartilage destruction in arthritis through a variety of mediators such as synovial RANKL expression, mast cells and pro-inflammatory cytokines. Investigation into sepsis at other sites has suggested improved outcomes with corticosteroid use despite the theoretical risks. This study therefore set out to review current literature with regards to a possible beneficial effect for corticosteroids in Septic Arthritis. A computerised search of the databases MEDLINE and CINAHL was conducted during November 2014 using the EBSCOhost web search engine in order to identify research articles relating to the use of corticosteroids in the treatment of septic arthritis. The search strategy revealed 223 unique ar",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:26342736
+SPB-0334,10.1136/acupmed-2017-011528,Acupuncture for overactive bladder in adults: a systematic review and meta-analysis.,"Mak Tony C, Chen Hai Yong, Cho William C",2019,Acupuncture in medicine : journal of the British Medical Acupuncture Society,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Overactive bladder is prevalent in adults over 40 years of age and its prevalence increases with age. The use of acupuncture in adults with overactive bladder is increasing globally. However, its effectiveness/efficacy and safety have not yet been confirmed. To determine the effectiveness/efficacy and safety of acupuncture and to identify the pattern of commonly used traditional acupuncture points in the management of overactive bladder in adults. Ten electronic English and Chinese language databases were systematically searched and two English together with four Chinese journals relevant to acupuncture were manually searched in libraries for randomised controlled trials (RCTs) of acupuncture for overactive bladder in adults from their inception to March 2017. The Cochrane risk of bias tool was used to assess the methodological quality of the RCTs. RevMan v.5.3 software was employed for data analysis. Seven eligible trials involving 695 participants were included. Meta-analysis showed ",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:31433197
+SPB-0335,10.1007/s00540-017-2310-x,Adjuncts to local anaesthetics in tonsillectomy: a systematic review and meta-analysis.,"Vlok R, Melhuish T M, Chong C, Ryan T, White Leigh D",2017,Journal of anesthesia,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"The infiltration of local anaesthetic agents has been shown to reduce post-tonsillectomy pain. A number of recent studies have shown that the addition of agents such as clonidine and dexamethasone improve the efficacy of nerve blocks and spinal anaesthesia. The aim of this review was to determine whether additives to local anaesthetic agents improve post-tonsillectomy outcomes. Four major databases were systematically searched for all relevant studies published up to August 2016. All study designs with a control group receiving local anaesthetic infiltration and an intervention receiving the same infiltration with an added agent were included in this review. These studies were then assessed for level of evidence and risk of bias. The data were then analysed both qualitatively and where appropriate by meta-analysis. We reviewed 11 randomised controlled trial (RCTs) that included 854 patients. Due to inconsistencies in the methods used to report outcomes, both quantitative and qualitativ",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:28120104
+SPB-0336,10.1016/j.jebdp.2018.12.004,Effect of Lasers on Dentine Hypersensitivity: Evidence From a Meta-analysis.,"Hu Meng-Long, Zheng Gang, Han Jian-Min, Yang Meng, Zhang You-Dong, et al.",2019,The journal of evidence-based dental practice,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"The aim of the study was to evaluate the immediate and long-term desensitizing effect of lasers in reducing dentine hypersensitivity (DH) compared with negative controls. Six databases were searched to identify relevant articles published up to June 8, 2018. Randomized controlled trials comparing lasers with placebo or no treatment control in adult patients who suffer from DH were included. The risk of bias was assessed according to the Cochrane guidelines, and the quality of the evidence was evaluated using the Grading of Recommendations Assessment, Development and Evaluation tool. Inverse-variance random effects meta-analyses of standardized mean differences and 95% confidence intervals were performed using the RevMan 5.3 software. Twenty-two randomized controlled trials were finally included in the meta-analysis, and 21 studies of these were conducted to analyze the immediate and long-term effects. All types of lasers had better immediate and long-term desensitizing effects on DH th",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:31326044
+SPB-0337,10.1136/bmjopen-2019-034298,Impact of point-of-care tests in community pharmacies: a systematic review and meta-analysis.,"Albasri Ali, Van den Bruel Ann, Hayward Gail, McManus Richard J, Sheppard James Peter, et al.",2020,BMJ open,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"To summarise the literature regarding the use of point-of-care test (POCT) in pharmacies versus control/usual care. Systematic review and random-effects meta-analysis in community pharmacy. MEDLINE, Cochrane Central Register of Controlled Trials, Embase, ClinicalTrial.gov and Web of Science databases were searched. Articles were included if they: involved a POCT conducted by a community pharmacist, member of pharmacy staff or local equivalent; measured a clinically relevant outcome for example, clinical parameter monitoring. No clinical condition or language limits were set. No patient involvement. Data were independently extracted by two members of the review team to capture changes in clinical care that resulted from the use of the POCTs. The methodological quality of included studies was assessed, using the Cochrane Risk of Bias tool and Newcastle-Ottawa scale. Thirteen of the 1584 articles found were included in the meta-analyses. Studies covered four therapeutic areas: targeted an",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:32414821
+SPB-0338,10.5664/jcsm.10022,The effect of robot interventions on sleep in adults: a systematic review and network meta-analysis.,"Støre Siri Jakobsson, Beckman Linda, Jakobsson Niklas",2022,Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Robotic pets or companion robots have demonstrated positive effects on several emotional and physiological factors in humans. Robots could constitute a complementary or alternative method to treat sleep problems, but individual studies on robots' effectiveness regarding sleep show mixed results. The aim of the current study was to compare the effects of robots, plush toys, and treatment as usual on sleep in adults. The current study is a systematic review and frequentist network meta-analysis of all randomized and cluster randomized controlled trials comparing the effects of robots, plush toys, and treatment as usual on total sleep time in adults. Four studies were included in the analysis. Three studies were considered to have a high risk of bias, whereas one was rated with some concerns. The studies comprised 381 participants. These participants were older adults, with or without dementia, living in nursing homes. The total sleep time was the only common sleep measure included in all",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:35404223
+SPB-0339,10.21037/apm.2020.02.35,The effect of breathing exercises on patients with GERD: a meta-analysis.,"Qiu Kaijie, Wang Jie, Chen Baiwen, Wang Haibiao, Ma Chenyang",2020,Annals of palliative medicine,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Breathing exercises can improve the symptoms of patients with gastroesophageal reflux disease (GERD), but their specific effect and function are disputed. To evaluate and conduct a meta-analysis on the effect of breathing exercises on patients with GERD. A literature search for randomized controlled trials (RCTs) and prospective studies on the effects of employing breathing exercises on patients with GERD was conducted of all major online English databases (PubMed, Embase, the Cochrane library, CENTRAL, Web of Science, AMED, and CINAHL). After the systematic review of all the studies according to inclusion and exclusion criteria, we analyzed the extracted data through meta-analysis by using RevMan 5.3 software. This thesis analyzes 7 studies (including three RCTs), which together involved 194 patients and 16 healthy volunteers. The primary outcomes of these studies included GERD symptoms, esophageal manometry, esophageal pH monitoring, laryngoscopic findings, and acid suppression usage",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:32233626
+SPB-0340,10.23736/S0375-9393.20.14073-2,Drugs for anesthesia and analgesia in the preterm infant.,"Tesoro Simonetta, Marchesini Vanessa, Fratini Giuseppe, Engelhardt Thomas, De Robertis Edoardo",2020,Minerva anestesiologica,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"There is largely an absence of validated evidence-based therapies in term- and preterm newborn infants, due to a lack of pharmacological clinical trials. As a consequence, the drugs and doses used in clinical practice are extrapolated from dose-ranging trials performed in older patients. Drugs administered to the preterm infant are invariably off-label. The aim of this current review is to identify commonly used anesthetic and analgesic agents in this patient population, assess the existing evidence base, in terms of safety, efficacy, pharmacokinetics and pharmacodynamics, current indications and doses. We searched the PubMed, Google Scholar, Web of Science, U.S. Food and Drug Administration and World Health Organization databases and analyzed any studies for general anesthesia; analgo-sedation; regional anesthesia; pharmacokinetics, pharmacodynamics and pharmacogenomics in this patient population. A total of 412 studies (meta-analysis, systematic reviews, randomized controlled trial (",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:32000473
+SPB-0341,10.1016/j.ijsu.2015.09.033,Intra-abdominal drainage for laparoscopic cholecystectomy: A systematic review and meta-analysis.,"Wong Chee S, Cousins Grainne, Duddy John C, Walsh Stewart R",2015,"International journal of surgery (London, England)",pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"To assess the effectiveness of intra-abdominal drainage (IAD) post laparoscopic cholecystectomy (LC). Main electronic databases [MEDLINE via Pubmed, EMBASE, Scopus, Web of Knowledge, Cochrane Central Register of Controlled Trials (CENTRAL) and the Cochrane Library, and clinical trial registry (ClinicalTrial.gov)] were searched for randomised controlled trial (RCT) reporting outcomes of IAD. The systematic review was conducted in accordance with the PRISMA guidelines and meta-analysis was analysed using fixed and random-effects models. Twelve RCTs involving 1763 patients (897 drained versus 866 without drain) were included in the final pooled analysis. There was no statistically significant different in the rate of intra-abdominal collections (RR 1.08, 95% CI 0.78 to 1.49; p = 0.65). IAD did not reduce the overall incidence of nausea and vomiting (RR 1.10, 95% CI 0.90 to 1.36; p = 0.36) and shoulder tip pain (RR 0.99, 95% CI 0.69 to 1.40; p = 0.93). Drain group had a significant higher ",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:26386402
+SPB-0342,10.1016/j.ijsu.2020.06.032,Four interventions for pediatric femoral shaft fractures: Network meta-analysis of randomized trials.,"Chen Zhao, Han Dawei, Wang Qingyu, Li Lianghua",2020,"International journal of surgery (London, England)",pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Fractures of the pediatric femoral shaft are uncommon, although serious injuries could lead to long-term disability, pain and an impaired quality of life. There are 4 main interventions: cast (C), plate fixation (PF), titanium elastic nail (TEN) and external fixation (EF). However, for pediatric patients under the age of 16, which intervention is the best choice remains a controversial topic. Therefore, a comprehensive network meta-analysis (NMA) is needed to summarize existing studies and to compare the safety and efficacy of the interventions for pediatric femoral shaft fractures. We searched through eight electronic databases (PubMed, Embase, Cochrane, Web of Science, CBM, CNKI, Wangfang, and VIP) for randomized controlled trials of femoral shaft fracture in pediatric patients, which were published until the end of March 2020. We performed a Bayesian NMA to integrate the adverse events and fracture union time of all interventions. Twenty-three randomized controlled trials with a tot",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:32622056
+SPB-0343,10.1016/j.jdent.2018.05.012,Effect of desensitizing toothpastes on dentine hypersensitivity: A systematic review and meta-analysis.,"Hu Meng-Long, Zheng Gang, Zhang You-Dong, Yan Xiang, Li Xiao-Chan, et al.",2018,Journal of dentistry,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"To evaluate the desensitizing effect of toothpastes that contain ingredients that act against dentine hypersensitivity (DH) and to compare this effect with negative controls. Five databases were searched to identify relevant articles published up to November 27, 2017. Randomized controlled trials (RCTs) comparing desensitizing toothpastes with a toothpastes without desensitizing component in adult patients that suffer from DH were included. The risk of bias was assessed according to the Cochrane guidelines, and the quality of the evidence was evaluated using the GRADE tool. Inverse variance random-effects meta-analyses of standardized mean differences (SMD) and 95% confidence intervals (CIs) were calculated using RevMan 5.3 software. 53 RCTs with 4796 patients were finally included in the meta-analysis. The toothpastes that contain active desensitization ingredients showed a better desensitizing effect on DH than the negative control, except the strontium- and amorphous calcium phospha",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:29787782
+SPB-0344,10.1177/0300060520964661,Role of platelet-rich plasma in the treatment of osteoarthritis: a meta-analysis.,"Ren Haijiang, Zhang Shouwei, Wang Xuejie, Li Zehui, Guo Wenlai",2020,The Journal of international medical research,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"The clinical efficacy of platelet-rich plasma (PRP) in the treatment of osteoarthritis remains controversial. In this paper, we evaluated the clinical efficacy of PRP in the treatment of osteoarthritis using meta-analysis, providing evidence for the selection of clinical treatment options. We performed a computer-based search of PubMed, Embase, and the Cochrane Library databases to retrieve articles using the search terms ""platelet-rich plasma"", ""osteoarthrosis"", and ""knee joint"". Quality evaluation and data extraction were performed. The combined effect was assessed using RevMan 5.3 software. Five randomized controlled trials, involving 320 patients, were included in this study. No significant differences were observed in the International Knee Documentation Committee score, visual analog scale (VAS) score, or the absolute value of the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score between the experimental and control groups. The absolute value of the VAS",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:33111611
+SPB-0345,10.1016/j.jclinepi.2020.03.014,Asking questions changes health-related behavior: an updated systematic review and meta-analysis.,"Miles Lisa M, Rodrigues Angela M, Sniehotta Falko F, French David P",2020,Journal of clinical epidemiology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"The question-behavior effect (QBE) refers to whether asking people questions can result in changes in behavior. Such changes in behavior can lead to bias in trials. This study aims to update a systematic review of randomized controlled trials investigating the QBE, in light of several large preregistered studies being published. A systematic search for newly published trials covered 2012 to July 2018. Eligible trials randomly allocated participants to measurement vs. non-measurement control conditions or to different forms of measurement. Studies that reported health-related behavior as outcomes were included. Forty-three studies (33 studies from the original systematic review and 10 new studies) compared measurement vs. no measurement. An overall small effect was found using a random effect model: standardized mean difference = 0.06 (95% CI: 0.02-0.09), n = 104,388. Statistical heterogeneity was substantial (I<sup>2</sup> = 54%). In an analysis restricted to studies with a low risk of",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:32229251
+SPB-0346,10.1038/s41598-020-70641-7,Surgical procedures in the pilonidal sinus disease: a systematic review and network meta-analysis.,"Bi Siwei, Sun Kaibo, Chen Shanshan, Gu Jun",2020,Scientific reports,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"The most appropriate surgical treatment for pilonidal sinus disease (PSD) is still in dispute. This study aims to comprehensively compare the outcomes of surgical interventions using network meta-analysis. Randomized controlled trial studies were searched systematically to identify all eligible studies in multiple databases and previous publications and Bayesian network meta-analysis was performed. Our primary outcome was the recurrence rate. Differences in the findings of the studies were explored in meta regressions and sensitivity analyses. The risk of bias of each study was assessed using the Cochrane risk of bias tool. Confidence in evidence was assessed using CINeMA (Confidence in Network Meta-Analysis). A total of 39 studies and 5,061 patients were identified and the most common surgical intervention was the Limberg flap. In network meta-analysis, modified Limberg flap and off-midline closure were associated with the lowest recurrence rate. However, the Karydakis flap was associ",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:32792519
+SPB-0347,10.3310/JNZT9406,Endometrial scratch to increase live birth rates in women undergoing first-time in vitro fertilisation: RCT and systematic review.,"Metwally Mostafa, Chatters Robin, Pye Clare, Dimairo Munya, White David, et al.",2022,"Health technology assessment (Winchester, England)",pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"In vitro fertilisation is a widely used reproductive technique that can be undertaken with or without intracytoplasmic sperm injection. The endometrial scratch procedure is an in vitro fertilisation 'add-on' that is sometimes provided prior to the first in vitro fertilisation cycle, but there is a lack of evidence to support its use. (1) To assess the clinical effectiveness, safety and cost-effectiveness of endometrial scratch compared with treatment as usual in women undergoing their first in vitro fertilisation cycle (the 'Endometrial Scratch Trial') and (2) to undertake a systematic review to combine the results of the Endometrial Scratch Trial with those of previous trials in which endometrial scratch was provided prior to the first in vitro fertilisation cycle. A pragmatic, multicentre, superiority, open-label, parallel-group, individually randomised controlled trial. Participants were randomised (1 : 1) via a web-based system to receive endometrial scratch or treatment as usual u",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:35129113
+SPB-0348,10.3310/hta21130,Support and Assessment for Fall Emergency Referrals (SAFER) 2: a cluster randomised trial and systematic review of clinical effectiveness and cost-effectiveness of new protocols for emergency ambulance paramedics to assess older people following a fall with referral to community-based care when appropriate.,"Snooks Helen A, Anthony Rebecca, Chatters Robin, Dale Jeremy, Fothergill Rachael, et al.",2017,"Health technology assessment (Winchester, England)",pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Emergency calls are frequently made to ambulance services for older people who have fallen, but ambulance crews often leave patients at the scene without any ongoing care. We evaluated a new clinical protocol which allowed paramedics to assess older people who had fallen and, if appropriate, refer them to community-based falls services. To compare outcomes, processes and costs of care between intervention and control groups; and to understand factors which facilitate or hinder use. Cluster randomised controlled trial. Participating paramedics at three ambulance services in England and Wales were based at stations randomised to intervention or control arms. Participants were aged 65 years and over, attended by a study paramedic for a fall-related emergency service call, and resident in the trial catchment areas. Intervention paramedics received a clinical protocol with referral pathway, training and support to change practice. Control paramedics continued practice as normal. The primary",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:28397649
+SPB-0349,10.1016/j.surg.2016.11.026,"Use of water-soluble contrast medium (gastrografin) does not decrease the need for operative intervention nor the duration of hospital stay in uncomplicated acute adhesive small bowel obstruction? A multicenter, randomized, clinical trial (Adhesive Small Bowel Obstruction Study) and systematic review.","Scotté Michel, Mauvais Francois, Bubenheim Michael, Cossé Cyril, Suaud Leslie, et al.",2017,Surgery,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"This study evaluated the association between oral gastrografin administration and the need for operative intervention in patients with presumed adhesive small bowel obstruction. Between October 2006 and August 2009, 242 patients with uncomplicated acute adhesive small bowel obstruction were included in a randomized, controlled trial (the Adhesive Small Bowel Obstruction Study, NCT00389116) and allocated to a gastrografin arm or a saline solution arm. The primary end point was the need for operative intervention within 48 hours of randomization. The secondary end points were the resection rate, the time interval between the initial computed tomography and operative intervention, the time interval between oral refeeding and discharge, risk factors for the failure of nonoperative management, in-hospital mortality, duration of stay, and recurrence or death after discharge. We performed a systematic review of the literature in order to evaluate the relationship between use of gastrografin a",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:28087066
+SPB-0350,10.1097/CCM.0000000000001479,Effect of Perioperative Goal-Directed Hemodynamic Resuscitation Therapy on Outcomes Following Cardiac Surgery: A Randomized Clinical Trial and Systematic Review.,"Osawa Eduardo A, Rhodes Andrew, Landoni Giovanni, Galas Filomena R B G, Fukushima Julia T, et al.",2016,Critical care medicine,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"To evaluate the effects of goal-directed therapy on outcomes in high-risk patients undergoing cardiac surgery. A prospective randomized controlled trial and an updated metaanalysis of randomized trials published from inception up to May 1, 2015. Surgical ICU within a tertiary referral university-affiliated teaching hospital. One hundred twenty-six high-risk patients undergoing coronary artery bypass surgery or valve repair. Patients were randomized to a cardiac output-guided hemodynamic therapy algorithm (goal-directed therapy group, n = 62) or to usual care (n = 64). In the goal-directed therapy arm, a cardiac index of greater than 3 L/min/m was targeted with IV fluids, inotropes, and RBC transfusion starting from cardiopulmonary bypass and ending 8 hours after arrival to the ICU. The primary outcome was a composite endpoint of 30-day mortality and major postoperative complications. Patients from the goal-directed therapy group received a greater median (interquartile range) volume of",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:26646462
+SPB-0351,10.1016/j.autrev.2015.05.013,Efficacy of low-dose rituximab for the treatment of mixed cryoglobulinemia vasculitis: Phase II clinical trial and systematic review.,"Visentini Marcella, Tinelli Carmine, Colantuono Stefania, Monti Monica, Ludovisi Serena, et al.",2015,Autoimmunity reviews,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"To evaluate whether rituximab at a low dose of 250 mg/m(2) × 2 may be as effective as at higher dosages, most commonly 375 mg/m(2)×4, used in previous studies on the treatment of patients with refractory mixed cryoglobulinemia (MC) vasculitis associated with hepatitis C virus (HCV) infection. We conducted a phase 2, single-arm two-stage trial (EUDRACT n. 2008-000086-38) of low-dose rituximab in 52 patients with HCV-associated MC who were ineligible/intolerant or non-responder to antiviral therapy. The primary outcomes were response of vasculitis evaluated by the Birmingham Vasculitis Activity Score (BVAS) at months 3, 6 and 12, rate of relapses and time to relapse, and rate of adverse events. Our data were compared with those reported in 19 published studies selected among 291 reviewed in a literature search. The cumulative response rate (complete and partial) at month 3 was 81% in our patients, and 86% in 208 patients from studies using high-dose rituximab. The relapse rate and median",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:26031898
+SPB-0352,10.1016/S0140-6736(17)30260-X,"Quarter-dose quadruple combination therapy for initial treatment of hypertension: placebo-controlled, crossover, randomised trial and systematic review.","Chow Clara K, Thakkar Jay, Bennett Alex, Hillis Graham, Burke Michael, et al.",2017,"Lancet (London, England)",pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Globally, most patients with hypertension are treated with monotherapy, and control rates are poor because monotherapy only reduces blood pressure by around 9/5 mm Hg on average. There is a pressing need for blood pressure-control strategies with improved efficacy and tolerability. We aimed to assess whether ultra-low-dose combination therapy could meet these needs. We did a randomised, placebo-controlled, double-blind, crossover trial of a quadpill-a single capsule containing four blood pressure-lowering drugs each at quarter-dose (irbesartan 37·5 mg, amlodipine 1·25 mg, hydrochlorothiazide 6·25 mg, and atenolol 12·5 mg). Participants with untreated hypertension were enrolled from four centres in the community of western Sydney, NSW, Australia, mainly by general practitioners. Participants were randomly allocated by computer to either the quadpill or matching placebo for 4 weeks; this treatment was followed by a 2-week washout, then the other study treatment was administered for 4 wee",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:28190578
+SPB-0353,10.1136/ebmental-2022-300530,Can we mitigate the psychological impacts of social isolation using behavioural activation? Long-term results of the UK BASIL urgent public health COVID-19 pilot randomised controlled trial and living systematic review.,"Littlewood Elizabeth, McMillan Dean, Chew Graham Carolyn, Bailey Della, Gascoyne Samantha, et al.",2022,Evidence-based mental health,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Behavioural and cognitive interventions remain credible approaches in addressing loneliness and depression. There was a need to rapidly generate and assimilate trial-based data during COVID-19. We undertook a parallel pilot RCT of behavioural activation (a brief behavioural intervention) for depression and loneliness (Behavioural Activation in Social Isolation, the BASIL-C19 trial ISRCTN94091479). We also assimilate these data in a living systematic review (PROSPERO CRD42021298788) of cognitive and/or behavioural interventions. Participants (≥65 years) with long-term conditions were computer randomised to behavioural activation (n=47) versus care as usual (n=49). Primary outcome was PHQ-9. Secondary outcomes included loneliness (De Jong Scale). Data from the BASIL-C19 trial were included in a metanalysis of depression and loneliness. The 12 months adjusted mean difference for PHQ-9 was -0.70 (95% CI -2.61 to 1.20) and for loneliness was -0.39 (95% CI -1.43 to 0.65).The BASIL-C19 living",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:36223980
+SPB-0354,10.3310/hta19660,Saline in acute bronchiolitis RCT and economic evaluation: hypertonic saline in acute bronchiolitis - randomised controlled trial and systematic review.,"Everard Mark L, Hind Daniel, Ugonna Kelechi, Freeman Jennifer, Bradburn Mike, et al.",2015,"Health technology assessment (Winchester, England)",pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Acute bronchiolitis is the most common cause of hospitalisation in infancy. Supportive care and oxygen are the cornerstones of management. A Cochrane review concluded that the use of nebulised 3% hypertonic saline (HS) may significantly reduce the duration of hospitalisation. To test the hypothesis that HS reduces the time to when infants were assessed as being fit for discharge, defined as in air with saturations of > 92% for 6 hours, by 25%. Parallel-group, pragmatic randomised controlled trial, cost-utility analysis and systematic review. Ten UK hospitals. Infants with acute bronchiolitis requiring oxygen therapy were allocated within 4 hours of admission. Supportive care with oxygen as required, minimal handling and fluid administration as appropriate to the severity of the disease, 3% nebulised HS every ± 6 hours. The trial primary outcome was time until the infant met objective discharge criteria. Secondary end points included time to discharge and adverse events. The costs analy",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:26295732
+SPB-0355,10.3310/hta20500,"The feasibility of determining the effectiveness and cost-effectiveness of medication organisation devices compared with usual care for older people in a community setting: systematic review, stakeholder focus groups and feasibility randomised controlled trial.","Bhattacharya Debi, Aldus Clare F, Barton Garry, Bond Christine M, Boonyaprapa Sathon, et al.",2016,"Health technology assessment (Winchester, England)",pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Medication organisation devices (MODs) provide compartments for a patient's medication to be organised into the days of the week and the recommended times the medication should be taken. To define the optimal trial design for testing the clinical effectiveness and cost-effectiveness of MODs. The feasibility study comprised a systematic review and focus groups to inform a randomised controlled trial (RCT) design. The resulting features were tested on a small scale, using a 2 × 2 factorial design to compare MODs with usual packaging and to compare weekly with monthly supply. The study design was then evaluated. Potential participants were identified by medical practices. Aged over 75 years, prescribed at least three solid oral dosage form medications, unintentionally non-adherent and self-medicating. Participants were excluded if deemed by their health-care team to be unsuitable. One of three MODs widely used in routine clinical practice supplied either weekly or monthly. To identify the",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:27385430
+SPB-0356,10.1227/NEU.0000000000000624,Bleeding and infection with external ventricular drainage: a systematic review in comparison with adjudicated adverse events in the ongoing Clot Lysis Evaluating Accelerated Resolution of Intraventricular Hemorrhage Phase III (CLEAR-III IHV) trial.,"Dey Mahua, Stadnik Agnieszka, Riad Fady, Zhang Lingjiao, McBee Nichol, et al.",2015,Neurosurgery,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Retrospective series report varied rates of bleeding and infection with external ventricular drainage (EVD). There have been no prospective studies of these risks with systematic surveillance, threshold definitions, or independent adjudication. To analyze the rate of complications in the ongoing Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage Phase III (CLEAR III) trial, providing a comparison with a systematic review of complications of EVD in the literature. Patients were prospectively enrolled in the CLEAR III trial after placement of an EVD for obstructive intraventricular hemorrhage and randomized to receive recombinant tissue-type plasminogen activator or placebo. We counted any detected new hemorrhage (catheter tract hemorrhage or any other distant hemorrhage) on computed tomography scan within 30 days from the randomization. Meta-analysis of published series of EVD placement was compiled with STATA software. Growing or unstable hemorrhage was report",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:25635887
+SPB-0357,10.1097/PRS.0000000000004515,"Topical Aloe Vera Gel for Accelerated Wound Healing of Split-Thickness Skin Graft Donor Sites: A Double-Blind, Randomized, Controlled Trial and Systematic Review.","Burusapat Chairat, Supawan Monlada, Pruksapong Chatchai, Pitiseree Anont, Suwantemee Chaichoompol",2018,Plastic and reconstructive surgery,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Aloe vera has been used to treat wounds since ancient times. However, data regarding the efficacy of aloe vera for burns and split-thickness skin graft donor sites are inconclusive. A double-blind, randomized, controlled trial was conducted. Patients who underwent split-thickness skin graft harvesting from the thigh were included. Split-thickness skin graft donor sites were divided into two groups: the aloe vera group and the placebo group. The visual analogue scale score was used to evaluate pain, and complete epithelialization was assessed. The authors searched electronic databases and included only international clinical trials published in the English language. Twelve patients with 24 donor sites participated. Times to complete epithelization for the aloe vera and placebo groups were 11.5 ± 1.45 and 13.67 ± 1.61 days, respectively (p < 0.05). Visual analogue scale scores after wound dressing for the aloe vera and placebo groups were 17.18 ± 13.17 and 18.63 ± 11.20, respectively. No",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:29649056
+SPB-0358,10.1093/bja/aeu386,LiDCO-based fluid management in patients undergoing hip fracture surgery under spinal anaesthesia: a randomized trial and systematic review.,"Moppett I K, Rowlands M, Mannings A, Moran C G, Wiles M D, et al.",2015,British journal of anaesthesia,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Hip fracture is a condition with high mortality and morbidity in elderly frail patients. Intraoperative fluid optimization may be associated with benefit in this population. We investigated whether intraoperative fluid management using pulse-contour analysis cardiac monitoring, compared with standard care in patients undergoing spinal anaesthesia, would provide benefits in terms of reduced time until medically fit for discharge and postoperative complications. Patients undergoing surgical repair of fractured neck of femur, aged >60 yr, receiving spinal anaesthesia were enrolled in this single-centre, blinded, randomized, parallel group trial. Patients were allocated to either anaesthetist-directed fluid therapy or a pulse-contour-guided fluid optimization strategy using colloid (Gelofusine) boluses to optimize stroke volume. The primary outcome was time until medically fit for discharge. Secondary outcomes included postoperative complications, mobility, and mortality. We updated a syst",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:25500940
+SPB-0359,10.3310/hta21720,"Preventing blood-borne virus infection in people who inject drugs in the UK: systematic review, stakeholder interviews, psychosocial intervention development and feasibility randomised controlled trial.","Gilchrist Gail, Swan Davina, Shaw April, Keding Ada, Towers Sarah, et al.",2017,"Health technology assessment (Winchester, England)",pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Opioid substitution therapy and needle exchanges have reduced blood-borne viruses (BBVs) among people who inject drugs (PWID). Some PWID continue to share injecting equipment. To develop an evidence-based psychosocial intervention to reduce BBV risk behaviours and increase transmission knowledge among PWID, and conduct a feasibility trial among PWID comparing the intervention with a control. A pragmatic, two-armed randomised controlled, open feasibility trial. Service users were Steering Group members and co-developed the intervention. Peer educators co-delivered the intervention in London. NHS or third-sector drug treatment or needle exchanges in Glasgow, London, Wrexham and York, recruiting January and February 2016. Current PWID, aged ≥ 18 years. A remote, web-based computer randomisation system allocated participants to a three-session, manualised, psychosocial, gender-specific group intervention delivered by trained facilitators and BBV transmission information booklet plus treatm",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:29208190
+SPB-0360,10.1159/000511574,PREvention of VENous Thromboembolism in Hemorrhagic Stroke Patients - PREVENTIHS Study: A Randomized Controlled Trial and a Systematic Review and Meta-Analysis.,"Paciaroni Maurizio, Agnelli Giancarlo, Alberti Andrea, Becattini Cecilia, Guercini Francesco, et al.",2020,European neurology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"In this randomized trial, currently utilized standard treatments were compared with enoxaparin for the prevention of venous thromboembolism (VTE) in patients with intracerebral hemorrhage (ICH). Enoxaparin (0.4 mg daily for 10 days) was started after 72 h from the onset of ICH. The primary outcome was symptomatic or asymptomatic deep venous thrombosis as assessed by ultrasound at the end of study treatment. The safety of enoxaparin was also assessed. We included the results of this study in a meta-analysis of all relevant studies comparing anticoagulants with standard treatments or placebo. PREVENTIHS was prematurely stopped after the randomization of 73 patients, due to the low recruitment rate. The prevalence of any VTE at 10 days was 15.8% in the enoxaparin group and 20.0% in the control group (RR 0.79 [95% CI 0.29-2.12]); 2.6% of enoxaparin and 8.6% of standard therapy patients had severe bleedings (RR 0.31 [95% CI 0.03-2.82]). When these results were meta-analyzed with the results",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:33190135
+SPB-0361,10.11607/prd.2164,A mixed-model study assessing orthodontic tooth extrusion for the reestablishment of biologic width. A systematic review and exploratory randomized trial.,"Zenóbio Elton Gonçalves, Moreira Ricardo Carneiro, Soares Rodrigo Villamarin, Feres Magda, Chambrone Leandro, et al.",2015,The International journal of periodontics & restorative dentistry,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"This study assessed the use of orthodontic extrusion (OE) for biologic width reestablishment (BWR) and compared two protocols for BWR: periodontal flap surgery (FS) performed either before (FS + OE) or after (OE + FS) extrusion. Databases were screened up to March 2013 for studies on OE, and outcomes from 13 patients treated by OE + FS or FS + OE were assessed. The results of the literature showed that OE + fiberotomy led to a greater amount of root extrusion than OE alone. The clinical/radiographic assessment demonstrated no significant differences between groups (P > .05). Within groups, there was an improvement in the keratinized tissue (P = .034) and in probing depth (P = .025) for OE + FS.",,medicine,auto_pubmed_clean,scipeerai_collector_v1,pmid:25734703
+SPB-0362,10.1167/tvst.9.2.14,"Introduction to Machine Learning, Neural Networks, and Deep Learning.","Choi Rene Y, Coyner Aaron S, Kalpathy-Cramer Jayashree, Chiang Michael F, Campbell J Peter",2020,Translational vision science & technology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"To present an overview of current machine learning methods and their use in medical research, focusing on select machine learning techniques, best practices, and deep learning. A systematic literature search in PubMed was performed for articles pertinent to the topic of artificial intelligence methods used in medicine with an emphasis on ophthalmology. A review of machine learning and deep learning methodology for the audience without an extensive technical computer programming background. Artificial intelligence has a promising future in medicine; however, many challenges remain. The aim of this review article is to provide the nontechnical readers a layman's explanation of the machine learning methods being used in medicine today. The goal is to provide the reader a better understanding of the potential and challenges of artificial intelligence within the field of medicine.",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:32704420
+SPB-0363,10.1007/s11030-021-10217-3,Artificial intelligence to deep learning: machine intelligence approach for drug discovery.,"Gupta Rohan, Srivastava Devesh, Sahu Mehar, Tiwari Swati, Ambasta Rashmi K, et al.",2021,Molecular diversity,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Drug designing and development is an important area of research for pharmaceutical companies and chemical scientists. However, low efficacy, off-target delivery, time consumption, and high cost impose a hurdle and challenges that impact drug design and discovery. Further, complex and big data from genomics, proteomics, microarray data, and clinical trials also impose an obstacle in the drug discovery pipeline. Artificial intelligence and machine learning technology play a crucial role in drug discovery and development. In other words, artificial neural networks and deep learning algorithms have modernized the area. Machine learning and deep learning algorithms have been implemented in several drug discovery processes such as peptide synthesis, structure-based virtual screening, ligand-based virtual screening, toxicity prediction, drug monitoring and release, pharmacophore modeling, quantitative structure-activity relationship, drug repositioning, polypharmacology, and physiochemical ac",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:33844136
+SPB-0364,10.1016/j.jinf.2023.07.006,"Artificial intelligence, machine learning and deep learning: Potential resources for the infection clinician.","Theodosiou Anastasia A, Read Robert C",2023,The Journal of infection,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Artificial intelligence (AI), machine learning and deep learning (including generative AI) are increasingly being investigated in the context of research and management of human infection. We summarise recent and potential future applications of AI and its relevance to clinical infection practice. 1617 PubMed results were screened, with priority given to clinical trials, systematic reviews and meta-analyses. This narrative review focusses on studies using prospectively collected real-world data with clinical validation, and on research with translational potential, such as novel drug discovery and microbiome-based interventions. There is some evidence of clinical utility of AI applied to laboratory diagnostics (e.g. digital culture plate reading, malaria diagnosis, antimicrobial resistance profiling), clinical imaging analysis (e.g. pulmonary tuberculosis diagnosis), clinical decision support tools (e.g. sepsis prediction, antimicrobial prescribing) and public health outbreak managemen",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:37468046
+SPB-0365,10.1016/j.semcancer.2019.12.011,Machine and deep learning approaches for cancer drug repurposing.,"Issa Naiem T, Stathias Vasileios, Schürer Stephan, Dakshanamurthy Sivanesan",2021,Seminars in cancer biology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Knowledge of the underpinnings of cancer initiation, progression and metastasis has increased exponentially in recent years. Advanced ""omics"" coupled with machine learning and artificial intelligence (deep learning) methods have helped elucidate targets and pathways critical to those processes that may be amenable to pharmacologic modulation. However, the current anti-cancer therapeutic armamentarium continues to lag behind. As the cost of developing a new drug remains prohibitively expensive, repurposing of existing approved and investigational drugs is sought after given known safety profiles and reduction in the cost barrier. Notably, successes in oncologic drug repurposing have been infrequent. Computational in-silico strategies have been developed to aid in modeling biological processes to find new disease-relevant targets and discovering novel drug-target and drug-phenotype associations. Machine and deep learning methods have especially enabled leaps in those successes. This revi",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:31904426
+SPB-0366,10.1002/mp.13678,Machine and deep learning methods for radiomics.,"Avanzo Michele, Wei Lise, Stancanello Joseph, Vallières Martin, Rao Arvind, et al.",2020,Medical physics,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Radiomics is an emerging area in quantitative image analysis that aims to relate large-scale extracted imaging information to clinical and biological endpoints. The development of quantitative imaging methods along with machine learning has enabled the opportunity to move data science research towards translation for more personalized cancer treatments. Accumulating evidence has indeed demonstrated that noninvasive advanced imaging analytics, that is, radiomics, can reveal key components of tumor phenotype for multiple three-dimensional lesions at multiple time points over and beyond the course of treatment. These developments in the use of CT, PET, US, and MR imaging could augment patient stratification and prognostication buttressing emerging targeted therapeutic approaches. In recent years, deep learning architectures have demonstrated their tremendous potential for image segmentation, reconstruction, recognition, and classification. Many powerful open-source and commercial platform",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:32418336
+SPB-0367,10.1177/15353702231209421,Review of machine learning and deep learning models for toxicity prediction.,"Guo Wenjing, Liu Jie, Dong Fan, Song Meng, Li Zoe, et al.",2023,"Experimental biology and medicine (Maywood, N.J.)",pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"The ever-increasing number of chemicals has raised public concerns due to their adverse effects on human health and the environment. To protect public health and the environment, it is critical to assess the toxicity of these chemicals. Traditional in vitro and in vivo toxicity assays are complicated, costly, and time-consuming and may face ethical issues. These constraints raise the need for alternative methods for assessing the toxicity of chemicals. Recently, due to the advancement of machine learning algorithms and the increase in computational power, many toxicity prediction models have been developed using various machine learning and deep learning algorithms such as support vector machine, random forest, k-nearest neighbors, ensemble learning, and deep neural network. This review summarizes the machine learning- and deep learning-based toxicity prediction models developed in recent years. Support vector machine and random forest are the most popular machine learning algorithms, ",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:38057999
+SPB-0368,10.1016/j.drudis.2021.09.007,Machine-learning methods for ligand-protein molecular docking.,"Crampon Kevin, Giorkallos Alexis, Deldossi Myrtille, Baud Stéphanie, Steffenel Luiz Angelo",2022,Drug discovery today,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Artificial intelligence (AI) is often presented as a new Industrial Revolution. Many domains use AI, including molecular simulation for drug discovery. In this review, we provide an overview of ligand-protein molecular docking and how machine learning (ML), especially deep learning (DL), a subset of ML, is transforming the field by tackling the associated challenges.",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:34560276
+SPB-0369,10.2967/jnumed.118.220590,Artificial Intelligence in Nuclear Medicine.,"Nensa Felix, Demircioglu Aydin, Rischpler Christoph",2019,"Journal of nuclear medicine : official publication, Society of Nuclear Medicine",pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Despite the great media attention for artificial intelligence (AI), for many health care professionals the term and the functioning of AI remain a ""black box,"" leading to exaggerated expectations on the one hand and unfounded fears on the other. In this review, we provide a conceptual classification and a brief summary of the technical fundamentals of AI. Possible applications are discussed on the basis of a typical work flow in medical imaging, grouped by planning, scanning, interpretation, and reporting. The main limitations of current AI techniques, such as issues with interpretability or the need for large amounts of annotated data, are briefly addressed. Finally, we highlight the possible impact of AI on the nuclear medicine profession, the associated challenges and, last but not least, the opportunities.",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:31481587
+SPB-0370,10.1016/j.cub.2019.02.034,Neural network models and deep learning.,"Kriegeskorte Nikolaus, Golan Tal",2019,Current biology : CB,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Originally inspired by neurobiology, deep neural network models have become a powerful tool of machine learning and artificial intelligence. They can approximate functions and dynamics by learning from examples. Here we give a brief introduction to neural network models and deep learning for biologists. We introduce feedforward and recurrent networks and explain the expressive power of this modeling framework and the backpropagation algorithm for setting the parameters. Finally, we consider how deep neural network models might help us understand brain computation.",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:30939301
+SPB-0371,10.1186/s13073-021-00930-x,DeepProg: an ensemble of deep-learning and machine-learning models for prognosis prediction using multi-omics data.,"Poirion Olivier B, Jing Zheng, Chaudhary Kumardeep, Huang Sijia, Garmire Lana X",2021,Genome medicine,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Multi-omics data are good resources for prognosis and survival prediction; however, these are difficult to integrate computationally. We introduce DeepProg, a novel ensemble framework of deep-learning and machine-learning approaches that robustly predicts patient survival subtypes using multi-omics data. It identifies two optimal survival subtypes in most cancers and yields significantly better risk-stratification than other multi-omics integration methods. DeepProg is highly predictive, exemplified by two liver cancer (C-index 0.73-0.80) and five breast cancer datasets (C-index 0.68-0.73). Pan-cancer analysis associates common genomic signatures in poor survival subtypes with extracellular matrix modeling, immune deregulation, and mitosis processes. DeepProg is freely available at https://github.com/lanagarmire/DeepProg.",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:34261540
+SPB-0372,10.1007/978-1-0716-1787-8_16,"Artificial Intelligence, Machine Learning, and Deep Learning in Real-Life Drug Design Cases.","Muller Christophe, Rabal Obdulia, Diaz Gonzalez Constantino",2022,"Methods in molecular biology (Clifton, N.J.)",pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"The discovery and development of drugs is a long and expensive process with a high attrition rate. Computational drug discovery contributes to ligand discovery and optimization, by using models that describe the properties of ligands and their interactions with biological targets. In recent years, artificial intelligence (AI) has made remarkable modeling progress, driven by new algorithms and by the increase in computing power and storage capacities, which allow the processing of large amounts of data in a short time. This review provides the current state of the art of AI methods applied to drug discovery, with a focus on structure- and ligand-based virtual screening, library design and high-throughput analysis, drug repurposing and drug sensitivity, de novo design, chemical reactions and synthetic accessibility, ADMET, and quantum mechanics.",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:34731478
+SPB-0373,10.1186/s12938-023-01187-8,"Artificial intelligence in glaucoma: opportunities, challenges, and future directions.","Huang Xiaoqin, Islam Md Rafiqul, Akter Shanjita, Ahmed Fuad, Kazami Ehsan, et al.",2023,Biomedical engineering online,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Artificial intelligence (AI) has shown excellent diagnostic performance in detecting various complex problems related to many areas of healthcare including ophthalmology. AI diagnostic systems developed from fundus images have become state-of-the-art tools in diagnosing retinal conditions and glaucoma as well as other ocular diseases. However, designing and implementing AI models using large imaging data is challenging. In this study, we review different machine learning (ML) and deep learning (DL) techniques applied to multiple modalities of retinal data, such as fundus images and visual fields for glaucoma detection, progression assessment, staging and so on. We summarize findings and provide several taxonomies to help the reader understand the evolution of conventional and emerging AI models in glaucoma. We discuss opportunities and challenges facing AI application in glaucoma and highlight some key themes from the existing literature that may help to explore future studies. Our goa",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:38102597
+SPB-0374,10.1021/acssensors.0c01424,Advancing Biosensors with Machine Learning.,"Cui Feiyun, Yue Yun, Zhang Yi, Zhang Ziming, Zhou H Susan",2020,ACS sensors,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Chemometrics play a critical role in biosensors-based detection, analysis, and diagnosis. Nowadays, as a branch of artificial intelligence (AI), machine learning (ML) have achieved impressive advances. However, novel advanced ML methods, especially deep learning, which is famous for image analysis, facial recognition, and speech recognition, has remained relatively elusive to the biosensor community. Herein, how ML can be beneficial to biosensors is systematically discussed. The advantages and drawbacks of most popular ML algorithms are summarized on the basis of sensing data analysis. Specially, deep learning methods such as convolutional neural network (CNN) and recurrent neural network (RNN) are emphasized. Diverse ML-assisted electrochemical biosensors, wearable electronics, SERS and other spectra-based biosensors, fluorescence biosensors and colorimetric biosensors are comprehensively discussed. Furthermore, biosensor networks and multibiosensor data fusion are introduced. This re",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:33185417
+SPB-0375,10.1097/ICU.0000000000000788,Artificial intelligence and ophthalmic surgery.,"Mishra Kapil, Leng Theodore",2021,Current opinion in ophthalmology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Artificial intelligence and deep learning have become important tools in extracting data from ophthalmic surgery to evaluate, teach, and aid the surgeon in all phases of surgical management. The purpose of this review is to highlight the ever-increasing intersection of computer vision, machine learning, and ophthalmic microsurgery. Deep learning algorithms are being applied to help evaluate and teach surgical trainees. Artificial intelligence tools are improving real-time surgical instrument tracking, phase segmentation, as well as enhancing the safety of robotic-assisted vitreoretinal surgery. Similar to strides appreciated in ophthalmic medical disease, artificial intelligence will continue to become an important part of surgical management of ocular conditions. Machine learning applications will help push the boundaries of what surgeons can accomplish to improve patient outcomes.",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:34397576
+SPB-0376,10.1007/s11427-020-1804-5,Application of deep learning in genomics.,"Liu Jianxiao, Li Jiying, Wang Hai, Yan Jianbing",2020,Science China. Life sciences,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"In recent years, deep learning has been widely used in diverse fields of research, such as speech recognition, image classification, autonomous driving and natural language processing. Deep learning has showcased dramatically improved performance in complex classification and regression problems, where the intricate structure in the high-dimensional data is difficult to discover using conventional machine learning algorithms. In biology, applications of deep learning are gaining increasing popularity in predicting the structure and function of genomic elements, such as promoters, enhancers, or gene expression levels. In this review paper, we described the basic concepts in machine learning and artificial neural network, followed by elaboration on the workflow of using convolutional neural network in genomics. Then we provided a concise introduction of deep learning applications in genomics and synthetic biology at the levels of DNA, RNA and protein. Finally, we discussed the current ch",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:33051704
+SPB-0377,10.1097/MOG.0000000000000945,Machine and deep learning in inflammatory bowel disease.,"Zulqarnain Fatima, Rhoads S Fisher, Syed Sana",2023,Current opinion in gastroenterology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"The Management of inflammatory bowel disease (IBD) has evolved with the introduction and widespread adoption of biologic agents; however, the advent of artificial intelligence technologies like machine learning and deep learning presents another watershed moment in IBD treatment. Interest in these methods in IBD research has increased over the past 10 years, and they offer a promising path to better clinical outcomes for IBD patients. Developing new tools to evaluate IBD and inform clinical management is challenging because of the expansive volume of data and requisite manual interpretation of data. Recently, machine and deep learning models have been used to streamline diagnosis and evaluation of IBD by automating review of data from several diagnostic modalities with high accuracy. These methods decrease the amount of time that clinicians spend manually reviewing data to formulate an assessment. Interest in machine and deep learning is increasing in medicine, and these methods are po",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:37144491
+SPB-0378,10.1002/art.42296,Artificial Intelligence and Deep Learning for Rheumatologists.,"McMaster Christopher, Bird Alix, Liew David F L, Buchanan Russell R, Owen Claire E, et al.",2022,"Arthritis & rheumatology (Hoboken, N.J.)",pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Deep learning has emerged as the leading method in machine learning, spawning a rapidly growing field of academic research and commercial applications across medicine. Deep learning could have particular relevance to rheumatology if correctly utilized. The greatest benefits of deep learning methods are seen with unstructured data frequently found in rheumatology, such as images and text, where traditional machine learning methods have struggled to unlock the trove of information held within these data formats. The basis for this success comes from the ability of deep learning to learn the structure of the underlying data. It is no surprise that the first areas of medicine that have started to experience impact from deep learning heavily rely on interpreting visual data, such as triaging radiology workflows and computer-assisted colonoscopy. Applications in rheumatology are beginning to emerge, with recent successes in areas as diverse as detecting joint erosions on plain radiography, p",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:35857865
+SPB-0379,10.1016/j.cbpa.2021.102111,Extendable and explainable deep learning for pan-cancer radiogenomics research.,"Liu Qian, Hu Pingzhao",2022,Current opinion in chemical biology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Radiogenomics is a field where medical images and genomic profiles are jointly analyzed to answer critical clinical questions. Specifically, people want to identify non-invasive imaging biomarkers that are associated with both genomic features and clinical outcomes. Deep learning is an advanced computer science technique that has been applied in many fields, including medical image and genomic data analysis. This review summarizes the current state of deep learning in pan-cancer radiogenomic research, discusses its limitations, and indicates the potential future directions. Traditional machine learning in radiomics, genomics, and radiogenomics have also been briefly discussed. We also summarize the main pan-cancer radiogenomic research resources. Two characteristics of deep learning are emphasized when discussing its application to pan-cancer radiogenomics, which are extendibility and explainability.",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:34999476
+SPB-0380,10.3390/s23042338,New Cognitive Deep-Learning CAPTCHA.,"Trong Nghia Dinh, Huong Thien Ho, Hoang Vinh Truong",2023,"Sensors (Basel, Switzerland)",pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"CAPTCHA (Completely Automated Public Turing test to tell Computers and Humans Apart), or HIP (Human Interactive Proof), has long been utilized to avoid bots manipulating web services. Over the years, various CAPTCHAs have been presented, primarily to enhance security and usability against new bots and cybercriminals carrying out destructive actions. Nevertheless, automated attacks supported by ML (Machine Learning), CNN (Convolutional Neural Network), and DNN (Deep Neural Network) have successfully broken all common conventional schemes, including text- and image-based CAPTCHAs. CNN/DNN have recently been shown to be extremely vulnerable to adversarial examples, which can consistently deceive neural networks by introducing noise that humans are incapable of detecting. In this study, the authors improve the security for CAPTCHA design by combining text-based, image-based, and cognitive CAPTCHA characteristics and applying adversarial examples and neural style transfer. Comprehend usabil",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:36850935
+SPB-0381,10.1186/s12968-019-0575-y,Machine learning in cardiovascular magnetic resonance: basic concepts and applications.,"Leiner Tim, Rueckert Daniel, Suinesiaputra Avan, Baeßler Bettina, Nezafat Reza, et al.",2019,Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Machine learning (ML) is making a dramatic impact on cardiovascular magnetic resonance (CMR) in many ways. This review seeks to highlight the major areas in CMR where ML, and deep learning in particular, can assist clinicians and engineers in improving imaging efficiency, quality, image analysis and interpretation, as well as patient evaluation. We discuss recent developments in the field of ML relevant to CMR in the areas of image acquisition & reconstruction, image analysis, diagnostic evaluation and derivation of prognostic information. To date, the main impact of ML in CMR has been to significantly reduce the time required for image segmentation and analysis. Accurate and reproducible fully automated quantification of left and right ventricular mass and volume is now available in commercial products. Active research areas include reduction of image acquisition and reconstruction time, improving spatial and temporal resolution, and analysis of perfusion and myocardial mapping. Altho",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:31590664
+SPB-0382,10.1007/s00330-019-06564-3,Deep learning: definition and perspectives for thoracic imaging.,"Chassagnon Guillaume, Vakalopolou Maria, Paragios Nikos, Revel Marie-Pierre",2020,European radiology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Relevance and penetration of machine learning in clinical practice is a recent phenomenon with multiple applications being currently under development. Deep learning-and especially convolutional neural networks (CNNs)-is a subset of machine learning, which has recently entered the field of thoracic imaging. The structure of neural networks, organized in multiple layers, allows them to address complex tasks. For several clinical situations, CNNs have demonstrated superior performance as compared with classical machine learning algorithms and in some cases achieved comparable or better performance than clinical experts. Chest radiography, a high-volume procedure, is a natural application domain because of the large amount of stored images and reports facilitating the training of deep learning algorithms. Several algorithms for automated reporting have been developed. The training of deep learning algorithm CT images is more complex due to the dimension, variability, and complexity of the",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:31811431
+SPB-0383,10.47391/JPMA.AKU-12,Understanding deep learning - challenges and prospects.,"Adnan Niha, Umer Fahad",2022,JPMA. The Journal of the Pakistan Medical Association,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"The developments in Artificial Intelligence have been on the rise since its advent. The advancements in this field have been the innovative research area across a wide range of industries, making its incorporation in dentistry inevitable. Artificial Intelligence techniques are making serious progress in the diagnostic and treatment planning aspects of dental clinical practice. This will ultimately help in the elimination of subjectivity and human error that are often part of radiographic interpretations, and will improve the overall efficiency of the process. The various types of Artificial Intelligence algorithms that exist today make the understanding of their application quite complex. The current narrative review was planned to make comprehension of Artificial Intelligence algorithms relatively straightforward. The focus was planned to be kept on the current developments and prospects of Artificial Intelligence in dentistry, especially Deep Learning and Convolutional Neural Network",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:35202373
+SPB-0384,10.1177/00031348221101490,Deep Learning Applications in Surgery: Current Uses and Future Directions.,"Morris Miranda X, Rajesh Aashish, Asaad Malke, Hassan Abbas, Saadoun Rakan, et al.",2023,The American surgeon,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Deep learning (DL) is a subset of machine learning that is rapidly gaining traction in surgical fields. Its tremendous capacity for powerful data-driven problem-solving has generated computational breakthroughs in many realms, with the fields of medicine and surgery becoming increasingly prominent avenues. Through its multi-layer architecture of interconnected neural networks, DL enables feature extraction and pattern recognition of highly complex and large-volume data. Across various surgical specialties, DL is being applied to optimize both preoperative planning and intraoperative performance in new and innovative ways. Surgeons are now able to integrate deep learning tools into their practice to improve patient safety and outcomes. Through this review, we explore the applications of deep learning in surgery and related subspecialties with an aim to shed light on the practical utilization of this technology in the present and near future.",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:35567312
+SPB-0385,10.7717/peerj.13152,Computational bioacoustics with deep learning: a review and roadmap.,Stowell Dan,2022,PeerJ,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Animal vocalisations and natural soundscapes are fascinating objects of study, and contain valuable evidence about animal behaviours, populations and ecosystems. They are studied in bioacoustics and ecoacoustics, with signal processing and analysis an important component. Computational bioacoustics has accelerated in recent decades due to the growth of affordable digital sound recording devices, and to huge progress in informatics such as big data, signal processing and machine learning. Methods are inherited from the wider field of deep learning, including speech and image processing. However, the tasks, demands and data characteristics are often different from those addressed in speech or music analysis. There remain unsolved problems, and tasks for which evidence is surely present in many acoustic signals, but not yet realised. In this paper I perform a review of the state of the art in deep learning for computational bioacoustics, aiming to clarify key concepts and identify and ana",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:35341043
+SPB-0386,10.1177/15353702231214259,Machine learning and deep learning for brain tumor MRI image segmentation.,"Khan Md Kamrul Hasan, Guo Wenjing, Liu Jie, Dong Fan, Li Zoe, et al.",2023,"Experimental biology and medicine (Maywood, N.J.)",pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Brain tumors are often fatal. Therefore, accurate brain tumor image segmentation is critical for the diagnosis, treatment, and monitoring of patients with these tumors. Magnetic resonance imaging (MRI) is a commonly used imaging technique for capturing brain images. Both machine learning and deep learning techniques are popular in analyzing MRI images. This article reviews some commonly used machine learning and deep learning techniques for brain tumor MRI image segmentation. The limitations and advantages of the reviewed machine learning and deep learning methods are discussed. Even though each of these methods has a well-established status in their individual domains, the combination of two or more techniques is currently an emerging trend.",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:38102956
+SPB-0387,10.1038/s41588-018-0295-5,A primer on deep learning in genomics.,"Zou James, Huss Mikael, Abid Abubakar, Mohammadi Pejman, Torkamani Ali, et al.",2019,Nature genetics,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Deep learning methods are a class of machine learning techniques capable of identifying highly complex patterns in large datasets. Here, we provide a perspective and primer on deep learning applications for genome analysis. We discuss successful applications in the fields of regulatory genomics, variant calling and pathogenicity scores. We include general guidance for how to effectively use deep learning methods as well as a practical guide to tools and resources. This primer is accompanied by an interactive online tutorial.",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:30478442
+SPB-0388,10.3390/ijms23126610,"Editorial of Special Issue ""Deep Learning and Machine Learning in Bioinformatics"".","Kang Mingon, Oh Jung Hun",2022,International journal of molecular sciences,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"In recent years, deep learning has emerged as a highly active research field, achieving great success in various machine learning areas, including image processing, speech recognition, and natural language processing, and now rapidly becoming a dominant tool in biomedicine [...].",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:35743052
+SPB-0389,10.1053/j.ackd.2021.07.004,"Deep Learning in Kidney Ultrasound: Overview, Frontiers, and Challenges.","De Jesus-Rodriguez Hector J, Morgan Matthew A, Sagreiya Hersh",2021,Advances in chronic kidney disease,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Ultrasonography is a practical imaging technique used in numerous health care settings. It is relatively inexpensive, portable, and safe, and it has dynamic capabilities that make it an invaluable tool for a wide variety of diagnostic and interventional studies. Recently, there has been a revolution in medical imaging using artificial intelligence (AI). A particularly potent form of AI is deep learning, in which the computer learns to recognize pixel or written data on its own without the selection of predetermined features, usually through a specific neural network architecture. Neural networks vary in architecture depending on their task, and key design considerations include the number of layers and complexity, data available, technical requirements, and domain knowledge. Deep learning models offer the potential for promising innovations to workflow, image quality, and vision tasks in sonography. However, there are key limitations and challenges in creating reliable and safe AI mode",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:34906311
+SPB-0390,10.1038/s41386-020-0767-z,Deep learning for small and big data in psychiatry.,"Koppe Georgia, Meyer-Lindenberg Andreas, Durstewitz Daniel",2021,Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Psychiatry today must gain a better understanding of the common and distinct pathophysiological mechanisms underlying psychiatric disorders in order to deliver more effective, person-tailored treatments. To this end, it appears that the analysis of 'small' experimental samples using conventional statistical approaches has largely failed to capture the heterogeneity underlying psychiatric phenotypes. Modern algorithms and approaches from machine learning, particularly deep learning, provide new hope to address these issues given their outstanding prediction performance in other disciplines. The strength of deep learning algorithms is that they can implement very complicated, and in principle arbitrary predictor-response mappings efficiently. This power comes at a cost, the need for large training (and test) samples to infer the (sometimes over millions of) model parameters. This appears to be at odds with the as yet rather 'small' samples available in psychiatric human research to date ",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:32668442
+SPB-0391,10.1155/2022/2645381,Text-Based Emotion Recognition Using Deep Learning Approach.,"Bharti Santosh Kumar, Varadhaganapathy S, Gupta Rajeev Kumar, Shukla Prashant Kumar, Bouye Mohamed, et al.",2022,Computational intelligence and neuroscience,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Sentiment analysis is a method to identify people's attitudes, sentiments, and emotions towards a given goal, such as people, activities, organizations, services, subjects, and products. Emotion detection is a subset of sentiment analysis as it predicts the unique emotion rather than just stating positive, negative, or neutral. In recent times, many researchers have already worked on speech and facial expressions for emotion recognition. However, emotion detection in text is a tedious task as cues are missing, unlike in speech, such as tonal stress, facial expression, pitch, etc. To identify emotions from text, several methods have been proposed in the past using natural language processing (NLP) techniques: the keyword approach, the lexicon-based approach, and the machine learning approach. However, there were some limitations with keyword- and lexicon-based approaches as they focus on semantic relations. In this article, we have proposed a hybrid (machine learning + deep learning) mo",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:36052029
+SPB-0392,10.1007/s11886-020-01348-4,Radiomics in Echocardiography: Deep Learning and Echocardiographic Analysis.,Kusunose Kenya,2020,Current cardiology reports,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Recent development in artificial intelligence (AI) for cardiovascular imaging analysis, involving deep learning, is the start of a new phase in the research field. We review the current state of AI in cardiovascular field and discuss about its potential to improve clinical workflows and accuracy of diagnosis. In the AI cardiovascular imaging field, there are many applications involving efficient image reconstruction, patient triage, and support for clinical decisions. These tools have a role to support repetitive clinical tasks. Although they will be powerful in some situations, these applications may have new potential in the hands of echo cardiologists, assisting but not replacing the human observer. We believe AI has the potential to improve the quality of echocardiography. Someday AI may be incorporated into the daily clinical setting, being an instrumental tool for cardiologists dealing with cardiovascular diseases.",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:32648059
+SPB-0393,10.1111/den.13896,Artificial intelligence and deep learning for small bowel capsule endoscopy.,"Trasolini Roberto, Byrne Michael F",2021,Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Capsule endoscopy is ideally suited to artificial intelligence-based interpretation given its reliance on pattern recognition in still images. Time saving viewing modes and lesion detection features currently available rely on machine learning algorithms, a form of artificial intelligence. Current software necessitates close human supervision given poor sensitivity relative to an expert reader. However, with the advent of deep learning, artificial intelligence is becoming increasingly reliable and will be increasingly relied upon. We review the major advances in artificial intelligence for capsule endoscopy in recent publications and briefly review artificial intelligence development for historical understanding. Importantly, recent advancements in artificial intelligence have not yet been incorporated into practice and it is immature to judge the potential of this technology based on current platforms. Remaining regulatory and standardization hurdles are being overcome and artificial ",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:33211357
+SPB-0394,10.3390/s22052017,A Systematic Review on Machine Learning and Deep Learning Models for Electronic Information Security in Mobile Networks.,"Gupta Chaitanya, Johri Ishita, Srinivasan Kathiravan, Hu Yuh-Chung, Qaisar Saeed Mian, et al.",2022,"Sensors (Basel, Switzerland)",pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Today's advancements in wireless communication technologies have resulted in a tremendous volume of data being generated. Most of our information is part of a widespread network that connects various devices across the globe. The capabilities of electronic devices are also increasing day by day, which leads to more generation and sharing of information. Similarly, as mobile network topologies become more diverse and complicated, the incidence of security breaches has increased. It has hampered the uptake of smart mobile apps and services, which has been accentuated by the large variety of platforms that provide data, storage, computation, and application services to end-users. It becomes necessary in such scenarios to protect data and check its use and misuse. According to the research, an artificial intelligence-based security model should assure the secrecy, integrity, and authenticity of the system, its equipment, and the protocols that control the network, independent of its genera",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:35271163
+SPB-0395,10.1016/j.sbi.2023.102548,Structure-based drug design with geometric deep learning.,"Isert Clemens, Atz Kenneth, Schneider Gisbert",2023,Current opinion in structural biology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Structure-based drug design uses three-dimensional geometric information of macromolecules, such as proteins or nucleic acids, to identify suitable ligands. Geometric deep learning, an emerging concept of neural-network-based machine learning, has been applied to macromolecular structures. This review provides an overview of the recent applications of geometric deep learning in bioorganic and medicinal chemistry, highlighting its potential for structure-based drug discovery and design. Emphasis is placed on molecular property prediction, ligand binding site and pose prediction, and structure-based de novo molecular design. The current challenges and opportunities are highlighted, and a forecast of the future of geometric deep learning for drug discovery is presented.",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:36842415
+SPB-0396,10.1111/vru.13144,Intelligent imaging: Applications of machine learning and deep learning in radiology.,"Currie Geoff, Rohren Eric",2022,Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Artificial intelligence (AI) in radiology is transforming medical image analysis. While applications in triaging for priority reporting and radiomic feature analysis have been widely reported, perhaps the most important applications lie in noise reduction, image optimization following dose reduction strategies, image reconstruction direct from projection data and generation of pseudo-CT for attenuation correction. There are common beneficial applications, and potential risks, between human radiology and veterinary radiology. Artificial intelligence may see recrafting of some responsibilities but offers AI augmentation of human driven systems. The redundancy afforded by human augmentation of AI and AI autonomy are not on the horizon, but rather are already here.",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:36514225
+SPB-0397,10.1016/j.drudis.2020.03.003,Machine learning models for drug-target interactions: current knowledge and future directions.,"D'Souza Sofia, Prema K V, Balaji Seetharaman",2020,Drug discovery today,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Predicting the binding affinity between compounds and proteins with reasonable accuracy is crucial in drug discovery. Computational prediction of binding affinity between compounds and targets greatly enhances the probability of finding lead compounds by reducing the number of wet-lab experiments. Machine-learning and deep-learning techniques using ligand-based and target-based approaches have been used to predict binding affinities, thereby saving time and cost in drug discovery efforts. In this review, we discuss about machine-learning and deep-learning models used in virtual screening to improve drug-target interaction (DTI) prediction. We also highlight current knowledge and future directions to guide further development in this field.",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:32171918
+SPB-0398,10.1016/j.path.2022.09.014,Applications of Deep Learning in Endocrine Neoplasms.,"Ramesh Siddhi, Dolezal James M, Pearson Alexander T",2023,Surgical pathology clinics,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Machine learning methods have been growing in prominence across all areas of medicine. In pathology, recent advances in deep learning (DL) have enabled computational analysis of histological samples, aiding in diagnosis and characterization in multiple disease areas. In cancer, and particularly endocrine cancer, DL approaches have been shown to be useful in tasks ranging from tumor grading to gene expression prediction. This review summarizes the current state of DL research in endocrine cancer histopathology with an emphasis on experimental design, significant findings, and key limitations.",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:36739164
+SPB-0399,10.2174/0929867327666200907141016,Deep Learning in Drug Target Interaction Prediction: Current and Future Perspectives.,"Abbasi Karim, Razzaghi Parvin, Poso Antti, Ghanbari-Ara Saber, Masoudi-Nejad Ali",2021,Current medicinal chemistry,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Drug-target Interactions (DTIs) prediction plays a central role in drug discovery. Computational methods in DTIs prediction have gained more attention because carrying out in vitro and in vivo experiments on a large scale is costly and time-consuming. Machine learning methods, especially deep learning, are widely applied to DTIs prediction. In this study, the main goal is to provide a comprehensive overview of deep learning-based DTIs prediction approaches. Here, we investigate the existing approaches from multiple perspectives. We explore these approaches to find out which deep network architectures are utilized to extract features from drug compound and protein sequences. Also, the advantages and limitations of each architecture are analyzed and compared. Moreover, we explore the process of how to combine descriptors for drug and protein features. Likewise, a list of datasets that are commonly used in DTIs prediction is investigated. Finally, current challenges are discussed and a sh",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:32895036
+SPB-0400,10.1007/s00234-021-02813-9,"Radiomics, machine learning, and artificial intelligence-what the neuroradiologist needs to know.","Wagner Matthias W, Namdar Khashayar, Biswas Asthik, Monah Suranna, Khalvati Farzad, et al.",2021,Neuroradiology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Artificial intelligence (AI) is playing an ever-increasing role in Neuroradiology. When designing AI-based research in neuroradiology and appreciating the literature, it is important to understand the fundamental principles of AI. Training, validation, and test datasets must be defined and set apart as priorities. External validation and testing datasets are preferable, when feasible. The specific type of learning process (supervised vs. unsupervised) and the machine learning model also require definition. Deep learning (DL) is an AI-based approach that is modelled on the structure of neurons of the brain; convolutional neural networks (CNN) are a commonly used example in neuroradiology. Radiomics is a frequently used approach in which a multitude of imaging features are extracted from a region of interest and subsequently reduced and selected to convey diagnostic or prognostic information. Deep radiomics uses CNNs to directly extract features and obviate the need for predefined featur",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:34537858
+SPB-0401,10.1016/j.bpg.2020.101712,Pitfalls in training and validation of deep learning systems.,"Eelbode Tom, Sinonquel Pieter, Maes Frederik, Bisschops Raf",2021,Best practice & research. Clinical gastroenterology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"The number of publications in endoscopic journals that present deep learning applications has risen tremendously over the past years. Deep learning has shown great promise for automated detection, diagnosis and quality improvement in endoscopy. However, the interdisciplinary nature of these works has undoubtedly made it more difficult to estimate their value and applicability. In this review, the pitfalls and common misconducts when training and validating deep learning systems are discussed and some practical guidelines are proposed that should be taken into account when acquiring data and handling it to ensure an unbiased system that will generalize for application in routine clinical practice. Finally, some considerations are presented to ensure correct validation and comparison of AI systems.",,computer science,auto_pubmed_clean,scipeerai_collector_v1,pmid:34172245
+SPB-0402,10.1016/j.cell.2020.05.039,Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma.,"Ji Andrew L, Rubin Adam J, Thrane Kim, Jiang Sizun, Reynolds David L, et al.",2020,Cell,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"To define the cellular composition and architecture of cutaneous squamous cell carcinoma (cSCC), we combined single-cell RNA sequencing with spatial transcriptomics and multiplexed ion beam imaging from a series of human cSCCs and matched normal skin. cSCC exhibited four tumor subpopulations, three recapitulating normal epidermal states, and a tumor-specific keratinocyte (TSK) population unique to cancer, which localized to a fibrovascular niche. Integration of single-cell and spatial data mapped ligand-receptor networks to specific cell types, revealing TSK cells as a hub for intercellular communication. Multiple features of potential immunosuppression were observed, including T regulatory cell (Treg) co-localization with CD8 T cells in compartmentalized tumor stroma. Finally, single-cell characterization of human tumor xenografts and in vivo CRISPR screens identified essential roles for specific tumor subpopulation-enriched gene networks in tumorigenesis. These data define cSCC tumor",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:32579974
+SPB-0403,10.1038/nmeth.4177,Pooled CRISPR screening with single-cell transcriptome readout.,"Datlinger Paul, Rendeiro André F, Schmidl Christian, Krausgruber Thomas, Traxler Peter, et al.",2017,Nature methods,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"CRISPR-based genetic screens are accelerating biological discovery, but current methods have inherent limitations. Widely used pooled screens are restricted to simple readouts including cell proliferation and sortable marker proteins. Arrayed screens allow for comprehensive molecular readouts such as transcriptome profiling, but at much lower throughput. Here we combine pooled CRISPR screening with single-cell RNA sequencing into a broadly applicable workflow, directly linking guide RNA expression to transcriptome responses in thousands of individual cells. Our method for CRISPR droplet sequencing (CROP-seq) enables pooled CRISPR screens with single-cell transcriptome resolution, which will facilitate high-throughput functional dissection of complex regulatory mechanisms and heterogeneous cell populations.",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:28099430
+SPB-0404,10.1016/j.cell.2022.02.015,Spatial CRISPR genomics identifies regulators of the tumor microenvironment.,"Dhainaut Maxime, Rose Samuel A, Akturk Guray, Wroblewska Aleksandra, Nielsen Sebastian R, et al.",2022,Cell,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"While CRISPR screens are helping uncover genes regulating many cell-intrinsic processes, existing approaches are suboptimal for identifying extracellular gene functions, particularly in the tissue context. Here, we developed an approach for spatial functional genomics called Perturb-map. We applied Perturb-map to knock out dozens of genes in parallel in a mouse model of lung cancer and simultaneously assessed how each knockout influenced tumor growth, histopathology, and immune composition. Moreover, we paired Perturb-map and spatial transcriptomics for unbiased analysis of CRISPR-edited tumors. We found that in Tgfbr2 knockout tumors, the tumor microenvironment (TME) was converted to a fibro-mucinous state, and T cells excluded, concomitant with upregulated TGFβ and TGFβ-mediated fibroblast activation, indicating that TGFβ-receptor loss on cancer cells increased TGFβ bioavailability and its immunosuppressive effects on the TME. These studies establish Perturb-map for functional genomi",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:35290801
+SPB-0405,10.1016/j.cell.2016.11.048,A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response.,"Adamson Britt, Norman Thomas M, Jost Marco, Cho Min Y, Nuñez James K, et al.",2016,Cell,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Functional genomics efforts face tradeoffs between number of perturbations examined and complexity of phenotypes measured. We bridge this gap with Perturb-seq, which combines droplet-based single-cell RNA-seq with a strategy for barcoding CRISPR-mediated perturbations, allowing many perturbations to be profiled in pooled format. We applied Perturb-seq to dissect the mammalian unfolded protein response (UPR) using single and combinatorial CRISPR perturbations. Two genome-scale CRISPR interference (CRISPRi) screens identified genes whose repression perturbs ER homeostasis. Subjecting ∼100 hits to Perturb-seq enabled high-precision functional clustering of genes. Single-cell analyses decoupled the three UPR branches, revealed bifurcated UPR branch activation among cells subject to the same perturbation, and uncovered differential activation of the branches across hits, including an isolated feedback loop between the translocon and IRE1α. These studies provide insight into how the three se",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:27984733
+SPB-0406,10.1016/j.jbiotec.2018.06.303,Opportunities in biotechnology.,"Gartland Kevan M A, Gartland Jill S",2018,Journal of biotechnology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Strategies for biotechnology must take account of opportunities for research, innovation and business growth. At a regional level, public-private collaborations provide potential for such growth and the creation of centres of excellence. By considering recent progress in areas such as genomics, healthcare diagnostics, synthetic biology, gene editing and bio-digital technologies, opportunities for smart, strategic and specialised investment are discussed. These opportunities often involve convergent or disruptive technologies, combining for example elements of pharma-science, molecular biology, bioinformatics and novel device development to enhance biotechnology and the life sciences. Analytical applications use novel devices in mobile health, predictive diagnostics and stratified medicine. Synthetic biology provides opportunities for new product development and increased efficiency for existing processes. Successful centres of excellence should promote public-private business partnersh",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:29890193
+SPB-0407,10.1016/j.cell.2016.11.038,Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens.,"Dixit Atray, Parnas Oren, Li Biyu, Chen Jenny, Fulco Charles P, et al.",2016,Cell,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Genetic screens help infer gene function in mammalian cells, but it has remained difficult to assay complex phenotypes-such as transcriptional profiles-at scale. Here, we develop Perturb-seq, combining single-cell RNA sequencing (RNA-seq) and clustered regularly interspaced short palindromic repeats (CRISPR)-based perturbations to perform many such assays in a pool. We demonstrate Perturb-seq by analyzing 200,000 cells in immune cells and cell lines, focusing on transcription factors regulating the response of dendritic cells to lipopolysaccharide (LPS). Perturb-seq accurately identifies individual gene targets, gene signatures, and cell states affected by individual perturbations and their genetic interactions. We posit new functions for regulators of differentiation, the anti-viral response, and mitochondrial function during immune activation. By decomposing many high content measurements into the effects of perturbations, their interactions, and diverse cell metadata, Perturb-seq dr",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:27984732
+SPB-0408,10.1089/crispr.2021.0099,CRISPR-Mediated Synergistic Epigenetic and Transcriptional Control.,"Dominguez Antonia A, Chavez Michael G, Urke Amanda, Gao Yuchen, Wang Lizhong, et al.",2022,The CRISPR journal,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Targeted activation of endogenous genes is an important approach for cell engineering. Here, we report that the nuclease-deactivated dCas9 fused to a transcriptional activator (VPR) and an epigenetic effector (the catalytic domain of histone acetyltransferase p300<sup>core</sup>) simultaneously, sequentially, or as a single quadripartite effector can lead to enhanced activation of target genes. The composite activator, VPRP, behaves more efficiently than individual activators across a set of genes in different cell types. We characterize off-target effects for host chromatin acetylation and transcriptome using the effectors. Our work demonstrates that transcriptional and epigenetic effectors can be used together to enhance gene activation and suggests the need for further optimization of epigenetic effectors to reduce off-targets.",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:35271371
+SPB-0409,10.1128/JB.00580-17,History of CRISPR-Cas from Encounter with a Mysterious Repeated Sequence to Genome Editing Technology.,"Ishino Yoshizumi, Krupovic Mart, Forterre Patrick",2018,Journal of bacteriology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Clustered regularly interspaced short palindromic repeat (CRISPR)-Cas systems are well-known acquired immunity systems that are widespread in archaea and bacteria. The RNA-guided nucleases from CRISPR-Cas systems are currently regarded as the most reliable tools for genome editing and engineering. The first hint of their existence came in 1987, when an unusual repetitive DNA sequence, which subsequently was defined as a CRISPR, was discovered in the Escherichia coli genome during an analysis of genes involved in phosphate metabolism. Similar sequence patterns were then reported in a range of other bacteria as well as in halophilic archaea, suggesting an important role for such evolutionarily conserved clusters of repeated sequences. A critical step toward functional characterization of the CRISPR-Cas systems was the recognition of a link between CRISPRs and the associated Cas proteins, which were initially hypothesized to be involved in DNA repair in hyperthermophilic archaea. Comparat",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:29358495
+SPB-0410,10.18632/oncotarget.9646,CRISPR/Cas9 therapeutics: a cure for cancer and other genetic diseases.,"Khan Faheem Ahmed, Pandupuspitasari Nuruliarizki Shinta, Chun-Jie Huang, Ao Zhou, Jamal Muhammad, et al.",2016,Oncotarget,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Cancer is caused by a series of alterations in genome and epigenome mostly resulting in activation of oncogenes or inactivation of cancer suppressor genes. Genetic engineering has become pivotal in the treatment of cancer and other genetic diseases, especially the formerly-niche use of clustered regularly interspaced short palindromic repeats (CRISPR) associated with Cas9. In defining its superior use, we have followed the recent advances that have been made in producing CRISPR/Cas9 as a therapy of choice. We also provide important genetic mutations where CRISPRs can be repurposed to create adaptive immunity to fight carcinomas and edit genetic mutations causing it. Meanwhile, challenges to CRISPR technology are also discussed with emphasis on ability of pathogens to evolve against CRISPRs. We follow the recent developments on the function of CRISPRs with different carriers which can efficiently deliver it to target cells; furthermore, analogous technologies are also discussed along CR",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:27250031
+SPB-0411,10.1016/j.cell.2018.11.029,A Genome-wide Framework for Mapping Gene Regulation via Cellular Genetic Screens.,"Gasperini Molly, Hill Andrew J, McFaline-Figueroa José L, Martin Beth, Kim Seungsoo, et al.",2019,Cell,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Over one million candidate regulatory elements have been identified across the human genome, but nearly all are unvalidated and their target genes uncertain. Approaches based on human genetics are limited in scope to common variants and in resolution by linkage disequilibrium. We present a multiplex, expression quantitative trait locus (eQTL)-inspired framework for mapping enhancer-gene pairs by introducing random combinations of CRISPR/Cas9-mediated perturbations to each of many cells, followed by single-cell RNA sequencing (RNA-seq). Across two experiments, we used dCas9-KRAB to perturb 5,920 candidate enhancers with no strong a priori hypothesis as to their target gene(s), measuring effects by profiling 254,974 single-cell transcriptomes. We identified 664 (470 high-confidence) cis enhancer-gene pairs, which were enriched for specific transcription factors, non-housekeeping status, and genomic and 3D conformational proximity to their target genes. This framework will facilitate the ",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:30612741
+SPB-0412,10.1038/nature16526,High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.,"Kleinstiver Benjamin P, Pattanayak Vikram, Prew Michelle S, Tsai Shengdar Q, Nguyen Nhu T, et al.",2016,Nature,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"CRISPR-Cas9 nucleases are widely used for genome editing but can induce unwanted off-target mutations. Existing strategies for reducing genome-wide off-target effects of the widely used Streptococcus pyogenes Cas9 (SpCas9) are imperfect, possessing only partial or unproven efficacies and other limitations that constrain their use. Here we describe SpCas9-HF1, a high-fidelity variant harbouring alterations designed to reduce non-specific DNA contacts. SpCas9-HF1 retains on-target activities comparable to wild-type SpCas9 with >85% of single-guide RNAs (sgRNAs) tested in human cells. Notably, with sgRNAs targeted to standard non-repetitive sequences, SpCas9-HF1 rendered all or nearly all off-target events undetectable by genome-wide break capture and targeted sequencing methods. Even for atypical, repetitive target sites, the vast majority of off-target mutations induced by wild-type SpCas9 were not detected with SpCas9-HF1. With its exceptional precision, SpCas9-HF1 provides an alternat",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:26735016
+SPB-0413,10.1038/s41592-020-0837-5,Targeted Perturb-seq enables genome-scale genetic screens in single cells.,"Schraivogel Daniel, Gschwind Andreas R, Milbank Jennifer H, Leonce Daniel R, Jakob Petra, et al.",2020,Nature methods,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"The transcriptome contains rich information on molecular, cellular and organismal phenotypes. However, experimental and statistical limitations constrain sensitivity and throughput of genetic screening with single-cell transcriptomics readout. To overcome these limitations, we introduce targeted Perturb-seq (TAP-seq), a sensitive, inexpensive and platform-independent method focusing single-cell RNA-seq coverage on genes of interest, thereby increasing the sensitivity and scale of genetic screens by orders of magnitude. TAP-seq permits routine analysis of thousands of CRISPR-mediated perturbations within a single experiment, detects weak effects and lowly expressed genes, and decreases sequencing requirements by up to 50-fold. We apply TAP-seq to generate perturbation-based enhancer-target gene maps for 1,778 enhancers within 2.5% of the human genome. We thereby show that enhancer-target association is jointly determined by three-dimensional contact frequency and epigenetic states, allo",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:32483332
+SPB-0414,10.1016/j.cell.2018.11.022,Coupled Single-Cell CRISPR Screening and Epigenomic Profiling Reveals Causal Gene Regulatory Networks.,"Rubin Adam J, Parker Kevin R, Satpathy Ansuman T, Qi Yanyan, Wu Beijing, et al.",2019,Cell,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Here, we present Perturb-ATAC, a method that combines multiplexed CRISPR interference or knockout with genome-wide chromatin accessibility profiling in single cells based on the simultaneous detection of CRISPR guide RNAs and open chromatin sites by assay of transposase-accessible chromatin with sequencing (ATAC-seq). We applied Perturb-ATAC to transcription factors (TFs), chromatin-modifying factors, and noncoding RNAs (ncRNAs) in ∼4,300 single cells, encompassing more than 63 genotype-phenotype relationships. Perturb-ATAC in human B lymphocytes uncovered regulators of chromatin accessibility, TF occupancy, and nucleosome positioning and identified a hierarchy of TFs that govern B cell state, variation, and disease-associated cis-regulatory elements. Perturb-ATAC in primary human epidermal cells revealed three sequential modules of cis-elements that specify keratinocyte fate. Combinatorial deletion of all pairs of these TFs uncovered their epistatic relationships and highlighted genom",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:30580963
+SPB-0415,10.1126/sciadv.add5907,Application of combined CRISPR screening for genetic and chemical-genetic interaction profiling in <i>Mycobacterium tuberculosis</i>.,"Yan Mei-Yi, Zheng Dandan, Li Si-Shang, Ding Xin-Yuan, Wang Chun-Liang, et al.",2022,Science advances,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"CRISPR screening, including CRISPR interference (CRISPRi) and CRISPR-knockout (CRISPR-KO) screening, has become a powerful technology in the genetic screening of eukaryotes. In contrast with eukaryotes, CRISPR-KO screening has not yet been applied to functional genomics studies in bacteria. Here, we constructed genome-scale CRISPR-KO and also CRISPRi libraries in Mycobacterium tuberculosis (Mtb). We first examined these libraries to identify genes essential for Mtb viability. Subsequent screening identified dozens of genes associated with resistance/susceptibility to the antitubercular drug bedaquiline (BDQ). Genetic and chemical validation of the screening results suggested that it provided a valuable resource to investigate mechanisms of action underlying the effects of BDQ and to identify chemical-genetic synergies that can be used to optimize tuberculosis therapy. In summary, our results demonstrate the potential for efficient genome-wide CRISPR-KO screening in bacteria and establi",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:36417506
+SPB-0416,10.1056/NEJMoa1502214,FTO Obesity Variant Circuitry and Adipocyte Browning in Humans.,"Claussnitzer Melina, Dankel Simon N, Kim Kyoung-Han, Quon Gerald, Meuleman Wouter, et al.",2015,The New England journal of medicine,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Genomewide association studies can be used to identify disease-relevant genomic regions, but interpretation of the data is challenging. The FTO region harbors the strongest genetic association with obesity, yet the mechanistic basis of this association remains elusive. We examined epigenomic data, allelic activity, motif conservation, regulator expression, and gene coexpression patterns, with the aim of dissecting the regulatory circuitry and mechanistic basis of the association between the FTO region and obesity. We validated our predictions with the use of directed perturbations in samples from patients and from mice and with endogenous CRISPR-Cas9 genome editing in samples from patients. Our data indicate that the FTO allele associated with obesity represses mitochondrial thermogenesis in adipocyte precursor cells in a tissue-autonomous manner. The rs1421085 T-to-C single-nucleotide variant disrupts a conserved motif for the ARID5B repressor, which leads to derepression of a potent ",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:26287746
+SPB-0417,10.1161/CIRCRESAHA.118.310998,Epigenomics: Technologies and Applications.,"Wang Kevin C, Chang Howard Y",2018,Circulation research,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"The advent of high-throughput epigenome mapping technologies has ushered in a new era of multiomics where powerful tools can now delineate and record different layers of genomic output. Integrating various components of the epigenome from these multiomics measurements allows the interrogation of cellular heterogeneity in addition to the discovery of molecular connectivity maps between the genome and its functional output. Mapping of chromatin accessibility dynamics and higher-order chromatin structure has enabled new levels of understanding of cell fate decisions, identity, and function in normal development, physiology, and disease. We provide a perspective on the progress of the epigenomics field and applications and anticipate an even greater revolution in our understanding of the human epigenome for years to come.",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:29700067
+SPB-0418,10.1002/yea.3098,New vectors for simple and streamlined CRISPR-Cas9 genome editing in Saccharomyces cerevisiae.,"Laughery Marian F, Hunter Tierra, Brown Alexander, Hoopes James, Ostbye Travis, et al.",2015,"Yeast (Chichester, England)",pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 technology is an important tool for genome editing because the Cas9 endonuclease can induce targeted DNA double-strand breaks. Targeting of the DNA break is typically controlled by a single-guide RNA (sgRNA), a chimeric RNA containing a structural segment important for Cas9 binding and a 20mer guide sequence that hybridizes to the genomic DNA target. Previous studies have demonstrated that CRISPR-Cas9 technology can be used for efficient, marker-free genome editing in Saccharomyces cerevisiae. However, introducing the 20mer guide sequence into yeast sgRNA expression vectors often requires cloning procedures that are complex, time-consuming and/or expensive. To simplify this process, we have developed a new sgRNA expression cassette with internal restriction enzyme sites that permit rapid, directional cloning of 20mer guide sequences. Here we describe a flexible set of vectors based on this design for cloning and ex",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:26305040
+SPB-0419,10.1016/j.jmb.2018.06.034,Functional Genomics via CRISPR-Cas.,"Ford Kyle, McDonald Daniella, Mali Prashant",2019,Journal of molecular biology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"RNA-guided CRISPR (clustered regularly interspaced short palindromic repeat)-associated Cas proteins have recently emerged as versatile tools to investigate and engineer the genome. The programmability of CRISPR-Cas has proven especially useful for probing genomic function in high-throughput. Facile single-guide RNA library synthesis allows CRISPR-Cas screening to rapidly investigate the functional consequences of genomic, transcriptomic, and epigenomic perturbations. Furthermore, by combining CRISPR-Cas perturbations with downstream single-cell analyses (flow cytometry, expression profiling, etc.), forward screens can generate robust data sets linking genotypes to complex cellular phenotypes. In the following review, we highlight recent advances in CRISPR-Cas genomic screening while outlining protocols and pitfalls associated with screen implementation. Finally, we describe current challenges limiting the utility of CRISPR-Cas screening as well as future research needed to resolve the",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:29959923
+SPB-0420,10.1038/nmeth.4604,On the design of CRISPR-based single-cell molecular screens.,"Hill Andrew J, McFaline-Figueroa José L, Starita Lea M, Gasperini Molly J, Matreyek Kenneth A, et al.",2018,Nature methods,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Several groups recently coupled CRISPR perturbations and single-cell RNA-seq for pooled genetic screens. We demonstrate that vector designs of these studies are susceptible to ∼50% swapping of guide RNA-barcode associations because of lentiviral template switching. We optimized a published alternative, CROP-seq, in which the guide RNA also serves as the barcode, and here confirm that this strategy performs robustly and doubled the rate at which guides are assigned to cells to 94%.",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:29457792
+SPB-0421,10.3389/fimmu.2022.1041451,High-content CRISPR screening in tumor immunology.,"Holcomb Erin A, Pearson Ashley N, Jungles Kassidy M, Tate Akshay, James Jadyn, et al.",2022,Frontiers in immunology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"CRISPR screening is a powerful tool that links specific genetic alterations to corresponding phenotypes, thus allowing for high-throughput identification of novel gene functions. Pooled CRISPR screens have enabled discovery of innate and adaptive immune response regulators in the setting of viral infection and cancer. Emerging methods couple pooled CRISPR screens with parallel high-content readouts at the transcriptomic, epigenetic, proteomic, and optical levels. These approaches are illuminating cancer immune evasion mechanisms as well as nominating novel targets that augment T cell activation, increase T cell infiltration into tumors, and promote enhanced T cell cytotoxicity. This review details recent methodological advances in high-content CRISPR screens and highlights the impact this technology is having on tumor immunology.",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:36479127
+SPB-0422,10.1016/j.biotechadv.2020.107672,CRISPR-based enrichment strategies for targeted sequencing.,"Schultzhaus Zachary, Wang Zheng, Stenger David",2021,Biotechnology advances,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"The ability to easily produce or procure sequencing data has expanded to be within the reach of most clinics and research laboratories, but the complexity of sequence analysis remains a hurdle for many scientists, and a decline in sequencing cost means that the generation of gratuitous information in a given experiment is a challenge that is more and more often being encountered. To address this issue, methods have been present, some dating to the advent of nucleic acid sequencing, for capturing, targeting, or otherwise enriching specific nucleic acids in order to obtain greater depth of reads from a small portion of sequences within a complex sample. However, many of these methods have been complicated and laborious, relying on the design of hundreds to thousands of oligonucleotide probes, fabrication of microarray chips, and long hybridization times. Here, we review these methods, their benefits and uses, and catalog and discuss the implications of a recent development that has enabl",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:33253795
+SPB-0423,10.1097/MOP.0000000000000283,Mutations in the noncoding genome.,"Scacheri Cheryl A, Scacheri Peter C",2015,Current opinion in pediatrics,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Clinical diagnostic sequencing currently focuses on identifying causal mutations in the exome, wherein most disease-causing mutations are known to occur. The rest of the genome is mostly comprised of regulatory elements that control gene expression, but these have remained largely unexplored in clinical diagnostics due to the high cost of whole genome sequencing and interpretive challenges. The purpose of this review is to illustrate examples of diseases caused by mutations in regulatory elements and introduce the diagnostic potential for whole genome sequencing. Different classes of functional elements and chromatin structure are described to provide the clinician with a foundation for understanding the basis of these mutations. The utilization of whole-genome sequence data, epigenomic maps and induced pluripotent stem (IPS) cell technologies facilitated the discovery that mutations in the pancreas-specific transcription factor 1a enhancer can cause isolated pancreatic agenesis. High ",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:26382709
+SPB-0424,10.1016/j.cbpa.2015.10.001,How specific is CRISPR/Cas9 really?,"O'Geen Henriette, Yu Abigail S, Segal David J",2015,Current opinion in chemical biology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"The specificity of RNA-guided nucleases has gathered considerable interest as they become broadly applied to basic research and therapeutic development. Reports of the simple generation of animal models and genome engineering of cells raised questions about targeting precision. Conflicting early reports led the field to believe that CRISPR/Cas9 system was promiscuous, leading to a variety of strategies for improving specificity and increasingly sensitive methods to detect off-target events. However, other studies have suggested that CRISPR/Cas9 is a highly specific genome-editing tool. This review will focus on deciphering and interpreting these seemingly opposing claims.",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:26517564
+SPB-0425,10.1073/pnas.2112279118,Metagenomic discovery of CRISPR-associated transposons.,"Rybarski James R, Hu Kuang, Hill Alexis M, Wilke Claus O, Finkelstein Ilya J",2021,Proceedings of the National Academy of Sciences of the United States of America,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"CRISPR-associated Tn7 transposons (CASTs) co-opt cas genes for RNA-guided transposition. CASTs are exceedingly rare in genomic databases; recent surveys have reported Tn7-like transposons that co-opt Type I-F, I-B, and V-K CRISPR effectors. Here, we expand the diversity of reported CAST systems via a bioinformatic search of metagenomic databases. We discover architectures for all known CASTs, including arrangements of the Cascade effectors, target homing modalities, and minimal V-K systems. We also describe families of CASTs that have co-opted the Type I-C and Type IV CRISPR-Cas systems. Our search for non-Tn7 CASTs identifies putative candidates that include a nuclease dead Cas12. These systems shed light on how CRISPR systems have coevolved with transposases and expand the programmable gene-editing toolkit.",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:34845024
+SPB-0426,10.1038/ncomms14406,CRISPR/Cpf1-mediated DNA-free plant genome editing.,"Kim Hyeran, Kim Sang-Tae, Ryu Jahee, Kang Beum-Chang, Kim Jin-Soo, et al.",2017,Nature communications,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Cpf1, a type V CRISPR effector, recognizes a thymidine-rich protospacer-adjacent motif and induces cohesive double-stranded breaks at the target site guided by a single CRISPR RNA (crRNA). Here we show that Cpf1 can be used as a tool for DNA-free editing of plant genomes. We describe the delivery of recombinant Cpf1 proteins with in vitro transcribed or chemically synthesized target-specific crRNAs into protoplasts isolated from soybean and wild tobacco. Designed crRNAs are unique and do not have similar sequences (≤3 mismatches) in the entire soybean reference genome. Targeted deep sequencing analyses show that mutations are successfully induced in FAD2 paralogues in soybean and AOC in wild tobacco. Unlike SpCas9, Cpf1 mainly induces various nucleotide deletions at target sites. No significant mutations are detected at potential off-target sites in the soybean genome. These results demonstrate that Cpf1-crRNA complex is an effective DNA-free genome-editing tool for plant genome editin",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:28205546
+SPB-0427,10.1126/science.adh7699,Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens.,"Morris John A, Caragine Christina, Daniloski Zharko, Domingo Júlia, Barry Timothy, et al.",2023,"Science (New York, N.Y.)",pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Most variants associated with complex traits and diseases identified by genome-wide association studies (GWAS) map to noncoding regions of the genome with unknown effects. Using ancestrally diverse, biobank-scale GWAS data, massively parallel CRISPR screens, and single-cell transcriptomic and proteomic sequencing, we discovered 124 cis-target genes of 91 noncoding blood trait GWAS loci. Using precise variant insertion through base editing, we connected specific variants with gene expression changes. We also identified trans-effect networks of noncoding loci when cis target genes encoded transcription factors or microRNAs. Networks were themselves enriched for GWAS variants and demonstrated polygenic contributions to complex traits. This platform enables massively parallel characterization of the target genes and mechanisms of human noncoding variants in both cis and trans.",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:37141313
+SPB-0428,10.1093/hmg/ddy120,Development and application of CRISPR/Cas9 technologies in genomic editing.,"Zhang Cui, Quan Renfu, Wang Jinfu",2018,Human molecular genetics,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Genomic editing to correct disease-causing mutations is a promising approach for the treatment of human diseases. As a simple and programmable nuclease-based genomic editing tool, the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) system has substantially improved the ability to make precise changes in the human genome. Rapid development of CRISPR-based technologies in recent years has expanded its application scope and promoted CRISPR-based therapies in preclinical trails. Here, we review the application of the CRISPR system over the last 2 years; including its development and application in base editing, transcription modulation and epigenetic editing, genomic-scale screening, and cell and embryo therapy. Finally, the prospects and challenges related to application of CRISPR/Cas9 technologies are discussed.",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:29659822
+SPB-0429,10.1038/nmeth.3630,Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements.,"Thakore Pratiksha I, D'Ippolito Anthony M, Song Lingyun, Safi Alexias, Shivakumar Nishkala K, et al.",2015,Nature methods,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Epigenome editing with the CRISPR (clustered, regularly interspaced, short palindromic repeats)-Cas9 platform is a promising technology for modulating gene expression to direct cell phenotype and to dissect the causal epigenetic mechanisms of gene regulation. Fusions of nuclease-inactive dCas9 to the Krüppel-associated box (KRAB) repressor (dCas9-KRAB) can silence target gene expression, but the genome-wide specificity and the extent of heterochromatin formation catalyzed by dCas9-KRAB are not known. We targeted dCas9-KRAB to the HS2 enhancer, a distal regulatory element that orchestrates the expression of multiple globin genes, and observed highly specific induction of H3K9 trimethylation (H3K9me3) at the enhancer and decreased chromatin accessibility of both the enhancer and its promoter targets. Targeted epigenetic modification of HS2 silenced the expression of multiple globin genes, with minimal off-target changes in global gene expression. These results demonstrate that repression",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:26501517
+SPB-0430,10.2174/1871520619666191014103711,CRISPR/Cas9 System and its Research Progress in Gene Therapy.,"Liu Wenlou, Yang Chunsheng, Liu Yanqun, Jiang Guan",2019,Anti-cancer agents in medicinal chemistry,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Genome editing refers to changing the genome sequence of an organism by knockout, insertion, and site mutation, resulting in changes in the genetic information of the organism. The clustered regularly interspaced short palindromic repeats (CRISPR)/ CRISPR-associated protein-9 nuclease (Cas9) system is a genome editing technique developed by the acquired immune system in the microbes, such as bacteria and archaebacteria, which targets and edits genome sequences according to the principle of complementary base pairing. This technique can be used to edit endogenous genomic DNA sequences in organisms accurately and has been widely used in fields, such as biotechnology, cancer gene therapy, and dermatology. In this review, we summarize the history, structure, mechanism, and application of CRISPR/Cas9 in gene therapy and dermatological diseases.",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:31633477
+SPB-0431,10.1016/j.molcel.2018.11.031,Target-Specific Precision of CRISPR-Mediated Genome Editing.,"Chakrabarti Anob M, Henser-Brownhill Tristan, Monserrat Josep, Poetsch Anna R, Luscombe Nicholas M, et al.",2019,Molecular cell,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"The CRISPR-Cas9 system has successfully been adapted to edit the genome of various organisms. However, our ability to predict the editing outcome at specific sites is limited. Here, we examined indel profiles at over 1,000 genomic sites in human cells and uncovered general principles guiding CRISPR-mediated DNA editing. We find that precision of DNA editing (i.e., recurrence of a specific indel) varies considerably among sites, with some targets showing one highly preferred indel and others displaying numerous infrequent indels. Editing precision correlates with editing efficiency and a preference for single-nucleotide homologous insertions. Precise targets and editing outcome can be predicted based on simple rules that mainly depend on the fourth nucleotide upstream of the protospacer adjacent motif (PAM). Indel profiles are robust, but they can be influenced by chromatin features. Our findings have important implications for clinical applications of CRISPR technology and reveal gener",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:30554945
+SPB-0432,10.1016/j.copbio.2014.11.007,Editing plant genomes with CRISPR/Cas9.,"Belhaj Khaoula, Chaparro-Garcia Angela, Kamoun Sophien, Patron Nicola J, Nekrasov Vladimir",2015,Current opinion in biotechnology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"CRISPR/Cas9 is a rapidly developing genome editing technology that has been successfully applied in many organisms, including model and crop plants. Cas9, an RNA-guided DNA endonuclease, can be targeted to specific genomic sequences by engineering a separately encoded guide RNA with which it forms a complex. As only a short RNA sequence must be synthesized to confer recognition of a new target, CRISPR/Cas9 is a relatively cheap and easy to implement technology that has proven to be extremely versatile. Remarkably, in some plant species, homozygous knockout mutants can be produced in a single generation. Together with other sequence-specific nucleases, CRISPR/Cas9 is a game-changing technology that is poised to revolutionise basic research and plant breeding.",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:25437637
+SPB-0433,10.1007/978-1-4939-2687-9_4,Annotation and Classification of CRISPR-Cas Systems.,"Makarova Kira S, Koonin Eugene V",2015,"Methods in molecular biology (Clifton, N.J.)",pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"The clustered regularly interspaced short palindromic repeats (CRISPR)-Cas (CRISPR-associated proteins) is a prokaryotic adaptive immune system that is represented in most archaea and many bacteria. Among the currently known prokaryotic defense systems, the CRISPR-Cas genomic loci show unprecedented complexity and diversity. Classification of CRISPR-Cas variants that would capture their evolutionary relationships to the maximum possible extent is essential for comparative genomic and functional characterization of this theoretically and practically important system of adaptive immunity. To this end, a multipronged approach has been developed that combines phylogenetic analysis of the conserved Cas proteins with comparison of gene repertoires and arrangements in CRISPR-Cas loci. This approach led to the current classification of CRISPR-Cas systems into three distinct types and ten subtypes for each of which signature genes have been identified. Comparative genomic analysis of the CRISPR",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:25981466
+SPB-0434,10.1007/s00059-017-4592-z,Precision medicine approach to genetic cardiomyopathy.,"Filonenko K, Katus H A, Meder B",2017,Herz,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,Precision medicine aims to achieve improved survival by strategies that recognize the genetic and phenotypic individuality of patients and stratify treatment accordingly. Genetic cardiomyopathies represent an ideal disease group to fully embark on this concept: they are in total frequent diseases with a marked morbidity and mortality and there is ample knowledge about their predisposing genetic factors and associated functional mechanisms. The current review highlights the genetic etiology and gives examples of the diverse treatment strategies that are envisaged in the future.,,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:28653114
+SPB-0435,10.1089/crispr.2021.0021,CRISPRclassify: Repeat-Based Classification of CRISPR Loci.,"Nethery Matthew A, Korvink Michael, Makarova Kira S, Wolf Yuri I, Koonin Eugene V, et al.",2021,The CRISPR journal,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Detection and classification of CRISPR-Cas systems in metagenomic data have become increasingly prevalent in recent years due to their potential for diverse applications in genome editing. Traditionally, CRISPR-Cas systems are classified through reference-based identification of proximate cas genes. Here, we present a machine learning approach for the detection and classification of CRISPR loci using repeat sequences in a cas-independent context, enabling identification of unclassified loci missed by traditional cas-based approaches. Using biological attributes of the CRISPR repeat, the core element in CRISPR arrays, and leveraging methods from natural language processing, we developed a machine learning model capable of accurate classification of CRISPR loci in an extensive set of metagenomes, resulting in an F1 measure of 0.82 across all predictions and an F1 measure of 0.97 when limiting to classifications with probabilities >0.85. Furthermore, assessing performance on novel repeats",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:34406047
+SPB-0436,10.1242/dev.182667,Using CRISPR to understand and manipulate gene regulation.,"Akinci Ersin, Hamilton Marisa C, Khowpinitchai Benyapa, Sherwood Richard I",2021,"Development (Cambridge, England)",pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Understanding how genes are expressed in the correct cell types and at the correct level is a key goal of developmental biology research. Gene regulation has traditionally been approached largely through observational methods, whereas perturbational approaches have lacked precision. CRISPR-Cas9 has begun to transform the study of gene regulation, allowing for precise manipulation of genomic sequences, epigenetic functionalization and gene expression. CRISPR-Cas9 technology has already led to the discovery of new paradigms in gene regulation and, as new CRISPR-based tools and methods continue to be developed, promises to transform our knowledge of the gene regulatory code and our ability to manipulate cell fate. Here, we discuss the current and future application of the emerging CRISPR toolbox toward predicting gene regulatory network behavior, improving stem cell disease modeling, dissecting the epigenetic code, reprogramming cell fate and treating diseases of gene dysregulation.",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:33913466
+SPB-0437,10.1016/j.jgg.2019.11.002,Advances in detecting and reducing off-target effects generated by CRISPR-mediated genome editing.,"Li Jinjing, Hong Shunyan, Chen Wanjin, Zuo Erwei, Yang Hui",2019,Journal of genetics and genomics = Yi chuan xue bao,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"CRISPR-mediated genome editing is a revolutionary technology for genome manipulation that uses the CRISPR-Cas systems and base editors. Currently, poor efficiency and off-target problems have impeded the application of CRISPR systems. The on-target efficiency has been improved in several advanced versions of CRISPR systems, whereas the off-target detection still remains a key challenge. Here, we outline the different versions of CRISPR systems and off-target detection strategies, discuss the merits and limitations of off-target detection methods, and provide potential implications for further gene editing research.",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:31911131
+SPB-0438,10.1101/gr.190124.115,Enabling functional genomics with genome engineering.,"Hilton Isaac B, Gersbach Charles A",2015,Genome research,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Advances in genome engineering technologies have made the precise control over genome sequence and regulation possible across a variety of disciplines. These tools can expand our understanding of fundamental biological processes and create new opportunities for therapeutic designs. The rapid evolution of these methods has also catalyzed a new era of genomics that includes multiple approaches to functionally characterize and manipulate the regulation of genomic information. Here, we review the recent advances of the most widely adopted genome engineering platforms and their application to functional genomics. This includes engineered zinc finger proteins, TALEs/TALENs, and the CRISPR/Cas9 system as nucleases for genome editing, transcription factors for epigenome editing, and other emerging applications. We also present current and potential future applications of these tools, as well as their current limitations and areas for future advances.",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:26430154
+SPB-0439,10.1136/jmedgenet-2015-103409,CRISPR-Cas9 for medical genetic screens: applications and future perspectives.,"Xue Hui-Ying, Ji Li-Juan, Gao Ai-Mei, Liu Ping, He Jing-Dong, et al.",2016,Journal of medical genetics,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"CRISPR-Cas9 (clustered regularly interspaced short palindromic repeats-CRISPR associated nuclease 9) systems have emerged as versatile and convenient (epi)genome editing tools and have become an important player in medical genetic research. CRISPR-Cas9 and its variants such as catalytically inactivated Cas9 (dead Cas9, dCas9) and scaffold-incorporating single guide sgRNA (scRNA) have been applied in various genomic screen studies. CRISPR screens enable high-throughput interrogation of gene functions in health and diseases. Compared with conventional RNAi screens, CRISPR screens incur less off-target effects and are more versatile in that they can be used in multiple formats such as knockout, knockdown and activation screens, and can target coding and non-coding regions throughout the genome. This powerful screen platform holds the potential of revolutionising functional genomic studies in the near future. Herein, we introduce the mechanisms of (epi)genome editing mediated by CRISPR-Cas",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:26673779
+SPB-0440,10.1038/s41467-019-12339-7,Enhanced CRISPR-based DNA demethylation by Casilio-ME-mediated RNA-guided coupling of methylcytosine oxidation and DNA repair pathways.,"Taghbalout Aziz, Du Menghan, Jillette Nathaniel, Rosikiewicz Wojciech, Rath Abhijit, et al.",2019,Nature communications,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Here we develop a methylation editing toolbox, Casilio-ME, that enables not only RNA-guided methylcytosine editing by targeting TET1 to genomic sites, but also by co-delivering TET1 and protein factors that couple methylcytosine oxidation to DNA repair activities, and/or promote TET1 to achieve enhanced activation of methylation-silenced genes. Delivery of TET1 activity by Casilio-ME1 robustly alters the CpG methylation landscape of promoter regions and activates methylation-silenced genes. We augment Casilio-ME1 to simultaneously deliver the TET1-catalytic domain and GADD45A (Casilio-ME2) or NEIL2 (Casilio-ME3) to streamline removal of oxidized cytosine intermediates to enhance activation of targeted genes. Using two-in-one effectors or modular effectors, Casilio-ME2 and Casilio-ME3 remarkably boost gene activation and methylcytosine demethylation of targeted loci. We expand the toolbox to enable a stable and expression-inducible system for broader application of the Casilio-ME platfo",,biology,auto_pubmed_clean,scipeerai_collector_v1,pmid:31541098
+SPB-0441,10.1016/j.jviscsurg.2023.10.005,"Surgery, innovation, research and sustainable development.","Slim Karem, Martin Frédéric",2024,Journal of visceral surgery,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"In the healthcare sector, surgery (especially in the operating theatre) is responsible for emission of greenhouse gases, which is a source of global warming. The goal of this largely quantitative assessment is to address three questions on carbon footprint associated with surgery, the role of primary and secondary prevention prior to surgical procedures, and incorporation of the carbon footprint into judgment criteria in research and surgical innovations. It appears that while the impact of surgery on global warming is undeniable, its extent depends on means of treatment and geographical location. Before and after an operation, primary, secondary and tertiary prevention accompanied by surgical sobriety (avoiding unnecessary or unjustified actions) can be virtuous in terms of sustainable development. However, the sanitary benefits of these actions are often opposed to environmental benefit, which has yet to be satisfactorily assessed. Lastly, the carbon footprint has yet to be incorpora",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:38071141
+SPB-0442,10.1021/acs.est.2c04388,Methane Emissions from Municipal Wastewater Collection and Treatment Systems.,"Song Cuihong, Zhu Jun-Jie, Willis John L, Moore Daniel P, Zondlo Mark A, et al.",2023,Environmental science & technology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Municipal wastewater collection and treatment systems are critical infrastructures, and they are also identified as major sources of anthropogenic CH<sub>4</sub> emissions that contribute to climate change. The actual CH<sub>4</sub> emissions at the plant- or regional level vary greatly due to site-specific conditions as well as high seasonal and diurnal variations. Here, we conducted the first quantitative analysis of CH<sub>4</sub> emissions from different types of sewers and water resource recovery facilities (WRRFs). We examined variations in CH<sub>4</sub> emissions associated with methods applied in different monitoring campaigns, and identified main CH<sub>4</sub> sources and sinks to facilitate carbon emission reduction efforts in the wastewater sector. We found plant-wide CH<sub>4</sub> emissions vary by orders of magnitude, from 0.01 to 110 g CH<sub>4</sub>/m<sup>3</sup> with high emissions associated with plants equipped with anaerobic digestion or stabilization ponds. Risin",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:36735881
+SPB-0443,10.3390/ijerph20031706,Research Progress and Hotspot Analysis of Residential Carbon Emissions Based on CiteSpace Software.,"Chen Yi, Chen Yinrong, Chen Kun, Liu Min",2023,International journal of environmental research and public health,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Residential carbon emissions are one of the critical causes of climate problems such as global warming. It is significant to explore the development and evolution trend of residential carbon emissions research for mitigating global climate change. However, there have been no studies that comprehensively review this research field. Based on the research papers on residential carbon emissions included in the Web of Science core database and China National Knowledge Infrastructure database, the CiteSpace bibliometric analysis software was used in this paper to draw the visual knowledge map of residential carbon emissions research and reveal its research status, research hotspots, and development trend. We found that residential carbon emissions research has gone through the stage of ""emergence-initiation-rapid development"", and the research in the United States and the United Kingdom has played a fundamental role in developing this research field. Research hotspots mainly focus on analyzi",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:36767072
+SPB-0444,10.1016/j.marpolbul.2023.115451,Estimation methods and reduction strategies of port carbon emissions - what literatures say?,"Wang Liang, Li Yining",2023,Marine pollution bulletin,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Carbon emissions from port operational activities significantly contribute to climate change and have gained attention from researchers. However, there is a notable deficiency in systematically analyzing port carbon emissions' estimation methods and reduction strategies. This study reviewed 49 academic literatures to examine the port's carbon emissions estimation methodologies, quantitative research outcomes, and reduction techniques. The analysis results revealed: (1) Estimates of port carbon emissions frequently tend to underestimate actual emissions due to the omission of specific sources. (2) Inherent variances across ports present challenges in establishing a universally applicable estimation methodology. (3) Port carbon emissions reduction strategies involve operational optimization, dispatching, equipment transformation, and energy management. Future research directions were proposed, including comprehensive emissions source estimation, harmonization of estimation methodologies,",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:37659387
+SPB-0445,10.3390/ijerph20032420,Achieving Carbon Neutrality through Urban Planning and Design.,"Wu Zhiqiang, Zhao Zichen, Gan Wei, Zhou Shiqi, Dong Wen, et al.",2023,International journal of environmental research and public health,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Much of the research on climate change has focused on carbon reduction in cities or countries. However, more attention needs to be paid to how to achieve carbon neutrality in the urban design and planning stage, and the lack of quantitative analysis of carbon related to urban space makes it difficult to locate urban space and provide direct guidance for urban planning and design. This study proposed three optimization paths to achieve carbon neutrality in multi-scale urban building clusters. Firstly, we reconstructed the quantitative calculation system of urban building communities with the goal of carbon neutrality; secondly, we screened the carbon source reduction and carbon sink interventions that are suitable for multi-scale urban building communities; finally, we constructed a carbon emission and carbon sink calculation system of planning and design schemes based on the layout of relevant elements of planning and design schemes with a grid cell of 100 × 100 m. In practice, there w",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:36767786
+SPB-0446,10.1016/j.jenvman.2022.116087,"From low carbon to carbon neutrality: A bibliometric analysis of the status, evolution and development trend.","Zhang Zheng, Hu Guangwen, Mu Xianzhong, Kong Li",2022,Journal of environmental management,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"With global climate change becoming increasingly serious, carbon neutrality, a key strategy to mitigate climate change, has attracted widespread attention. However, due to the multidisciplinary and complexity of carbon neutrality studies, as well as the diversification of research content, a comprehensive review and systematic synthesis of which is quite limited. In this paper, a bibliometric analysis on the topic of carbon neutrality is conducted to reveal the research progress from a quantitative and visual perspective and describe the evolution of research hotspots. The results show that carbon neutrality research is abundant at both the macro and micro levels. Low carbon development is the premise of carbon neutrality, and emission reduction and carbon sinks are the basis of carbon neutrality. The degree of research varies significantly in different countries, with China dominating in the number of publications, followed by the USA and the UK. The realization of carbon neutrality c",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:36041302
+SPB-0447,10.1111/cobi.14040,Retaining natural vegetation to safeguard biodiversity and humanity.,"Simmonds Jeremy S, Suarez-Castro Andres Felipe, Reside April E, Watson James E M, Allan James R, et al.",2023,Conservation biology : the journal of the Society for Conservation Biology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Global efforts to deliver internationally agreed goals to reduce carbon emissions, halt biodiversity loss, and retain essential ecosystem services have been poorly integrated. These goals rely in part on preserving natural (e.g., native, largely unmodified) and seminatural (e.g., low intensity or sustainable human use) forests, woodlands, and grasslands. To show how to unify these goals, we empirically derived spatially explicit, quantitative, area-based targets for the retention of natural and seminatural (e.g., native) terrestrial vegetation worldwide. We used a 250-m-resolution map of natural and seminatural vegetation cover and, from this, selected areas identified under different international agreements as being important for achieving global biodiversity, carbon, soil, and water targets. At least 67 million km<sup>2</sup> of Earth's terrestrial vegetation (∼79% of the area of vegetation remaining) required retention to contribute to biodiversity, climate, soil, and freshwater co",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:36424859
+SPB-0448,10.1016/j.jenvman.2023.118329,Heterogeneous effects of China's low-carbon city pilots policy.,"Lyu Jing, Liu Tianle, Cai Bofeng, Qi Ye, Zhang Xiaoling",2023,Journal of environmental management,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Global south countries, including China, have faced a challenging dilemma of reducing carbon emissions while maintaining rapid economic growth. The low-carbon city pilots (LCCPs) policy in China is a demonstration of how state power intervenes and commands national low-carbon development through voluntary policy tools. Our study, based on panel data of 331 cities from 2005 to 2019, evaluates the policy effect of all three batches of LCCPs and presents an analysis of time-varying effects through batch decomposition and synthetic difference-in-difference models. The study found that implementing low-carbon policies can significantly reduce total carbon emissions and carbon emissions per capita. However, the reduction in carbon emissions per unit of GDP is insignificant, and the policy effect varies according to the batches and their characteristics. The reduction effects in the first and second batches, as well as the insignificance or even increasing effects of the third batch, may be d",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:37379627
+SPB-0449,10.1016/j.jes.2022.07.038,Systematical analysis of sludge treatment and disposal technologies for carbon footprint reduction.,"Zhao Yingxin, Yang Zhifan, Niu Jiaojiao, Du Zihan, Federica Conti, et al.",2023,Journal of environmental sciences (China),pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"This study aims to comprehensively analyze the Greenhouse Gases (GHGs) emissions from current sewage sludge treatment and disposal technologies (building material, landfill, land spreading, anaerobic digestion, and thermochemical processes) based on the database of Science Citation Index (SCI) and Social Science Citation Index (SSCI) from 1998 to 2020. The general patterns, spatial distribution, and hotspots were provided by bibliometric analysis. A comparative quantitative analysis based on life cycle assessment (LCA) put forward the current emission situation and the key influencing factors of different technologies. The effective GHG emissions reduction methods were proposed to mitigate climate change. Results showed that incineration or building materials manufacturing of highly dewatered sludge, and land spreading after anaerobic digestion have the best GHG emissions reduction benefits. Biological treatment technologies and thermochemical processes have great potential for reducin",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:36801037
+SPB-0450,10.1038/s41586-023-06723-z,Integrated global assessment of the natural forest carbon potential.,"Mo Lidong, Zohner Constantin M, Reich Peter B, Liang Jingjing, de Miguel Sergio, et al.",2023,Nature,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Forests are a substantial terrestrial carbon sink, but anthropogenic changes in land use and climate have considerably reduced the scale of this system<sup>1</sup>. Remote-sensing estimates to quantify carbon losses from global forests<sup>2-5</sup> are characterized by considerable uncertainty and we lack a comprehensive ground-sourced evaluation to benchmark these estimates. Here we combine several ground-sourced<sup>6</sup> and satellite-derived approaches<sup>2,7,8</sup> to evaluate the scale of the global forest carbon potential outside agricultural and urban lands. Despite regional variation, the predictions demonstrated remarkable consistency at a global scale, with only a 12% difference between the ground-sourced and satellite-derived estimates. At present, global forest carbon storage is markedly under the natural potential, with a total deficit of 226 Gt (model range = 151-363 Gt) in areas with low human footprint. Most (61%, 139 Gt C) of this potential is in areas with exist",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:37957399
+SPB-0451,10.1038/s41477-023-01543-5,The global biogeography of tree leaf form and habit.,"Ma Haozhi, Crowther Thomas W, Mo Lidong, Maynard Daniel S, Renner Susanne S, et al.",2023,Nature plants,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Understanding what controls global leaf type variation in trees is crucial for comprehending their role in terrestrial ecosystems, including carbon, water and nutrient dynamics. Yet our understanding of the factors influencing forest leaf types remains incomplete, leaving us uncertain about the global proportions of needle-leaved, broadleaved, evergreen and deciduous trees. To address these gaps, we conducted a global, ground-sourced assessment of forest leaf-type variation by integrating forest inventory data with comprehensive leaf form (broadleaf vs needle-leaf) and habit (evergreen vs deciduous) records. We found that global variation in leaf habit is primarily driven by isothermality and soil characteristics, while leaf form is predominantly driven by temperature. Given these relationships, we estimate that 38% of global tree individuals are needle-leaved evergreen, 29% are broadleaved evergreen, 27% are broadleaved deciduous and 5% are needle-leaved deciduous. The aboveground bio",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:37872262
+SPB-0452,10.1007/s11356-021-18030-z,Computable general equilibrium models for sustainable development: past and future.,"Fabregat-Aibar Laura, Niñerola Angels, Pié Laia",2022,Environmental science and pollution research international,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Computable general equilibrium models (CGE) are used to estimate the ex-ante quantitative impact of a change in economic policy. There is a bulk of research in the field of sustainable development applying it for testing implementation of carbon taxation, analyzing reductions of greenhouse gas (GHG), or addressing agricultural issues to work the land efficiently. The main objective of this review is to provide an exhaustive analysis of the literature about these models and their evolution over the last 50 years. The search was conducted in the main academic databases (Scopus and Web of Science), where 1353 articles were found from 1966 to 2019 related to the topic. The results of the descriptives, relational, and content analyses carried out show the current state of the-art, trends, subfields of research, and future gaps to fulfill. This article contributes to the literature that uses CGE models providing an overview of its different applications in the field of sustainability. It giv",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:35303228
+SPB-0453,10.3390/ijerph192013507,Simulation of Vegetation Carbon Sink of Arbor Forest and Carbon Mitigation of Forestry Bioenergy in China.,"Ma Xiaozhe, Wu Leying, Zhu Yongbin, Wu Jing, Qin Yaochen",2022,International journal of environmental research and public health,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Mitigating carbon emissions through forest carbon sinks is one of the nature-based solutions to global warming. Forest ecosystems play a role as a carbon sink and an important source of bioenergy. China's forest ecosystems have significantly contributed to mitigating carbon emissions. However, there are relatively limited quantitative studies on the carbon mitigation effects of forestry bioenergy in China, so this paper simulated the carbon sequestration of Chinese arbor forest vegetation from 2018 to 2060 based on the CO2FIX model and accounted for the carbon emission reduction brought about by substituting forestry bioenergy for fossil energy, which is important for the formulation of policies to tackle climate change in the Chinese forestry sector. The simulation results showed that the carbon storage of all arbor forest vegetation in China increased year by year from 2018 to 2060, and, overall, it behaved as a carbon sink, with the annual carbon sink fluctuating in the region of 25",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:36294087
+SPB-0454,10.1016/j.envres.2023.115842,Comparing the variations and influencing factors of CH<sub>4</sub> emissions from paddies and wetlands under CO<sub>2</sub> enrichment: A data synthesis in the last three decades.,"Yu Haiyang, Zhang Xuechen, Meng Xiangtian, Luo Dan, Yue Zhengfu, et al.",2023,Environmental research,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Understanding and quantifying the impact of elevated tropospheric carbon dioxide concentration (e [CO<sub>2</sub>]) on methane (CH<sub>4</sub>) globally is important for effectively assessing and mitigating climate warming. Paddies and wetlands are the two important sources of CH<sub>4</sub> emissions. Yet, a quantitative synthetic investigation of the effects of e [CO<sub>2</sub>] on CH<sub>4</sub> emissions from paddies and wetlands on a global scale has not been conducted. Here, we conducted a meta-analysis of 488 observation cases from 40 studies to assess the long-term effects of e [CO<sub>2</sub>] (ambient [CO<sub>2</sub>]+ 53-400 μmol mol<sup>-1</sup>) on CH<sub>4</sub> emissions and to identify the relevant key drivers. On aggregate, e [CO<sub>2</sub>] increased CH<sub>4</sub> emissions by 25.7% (p < 0.05) from paddies but did not affect CH<sub>4</sub> emissions from wetlands (-3.29%; p > 0.05). The e [CO<sub>2</sub>] effects on paddy CH<sub>4</sub> emissions were positively re",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:37024028
+SPB-0455,10.3390/ijerph20010145,Driving Effect of Decoupling Provincial Industrial Economic Growth and Industrial Carbon Emissions in China.,"Hua Jingfen, Gao Junli, Chen Ke, Li Jiaqi",2022,International journal of environmental research and public health,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"China is facing the dual challenges of fostering economic growth and mounting an effective response to climate change, so it is vital to continue promoting industrial carbon emission reduction. This paper uses panel data from 1998 to 2019 to measure the industrial carbon emissions of 30 provinces in China. The Tapio decoupling and IPAT (Impact = Population × Affluence × Technology)-based decoupling models are used to analyze each province's velocity and quantity decoupling index for industrial carbon emissions. The fixed effect model analyzes the influencing factors for carbon decoupling. The results show that the industrial carbon emissions of various provinces in China are increasing yearly, but there are significant differences among provinces. The carbon decoupling of the industrial economy in most provinces is weak, and the quantitative decoupling index is better than the velocity decoupling index. The cleanliness of energy, balance, and labor productivity significantly affect the",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:36612465
+SPB-0456,10.1111/gcb.15342,Can N<sub>2</sub> O emissions offset the benefits from soil organic carbon storage?,"Guenet Bertrand, Gabrielle Benoit, Chenu Claire, Arrouays Dominique, Balesdent Jérôme, et al.",2021,Global change biology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"To respect the Paris agreement targeting a limitation of global warming below 2°C by 2100, and possibly below 1.5°C, drastic reductions of greenhouse gas emissions are mandatory but not sufficient. Large-scale deployment of other climate mitigation strategies is also necessary. Among these, increasing soil organic carbon (SOC) stocks is an important lever because carbon in soils can be stored for long periods and land management options to achieve this already exist and have been widely tested. However, agricultural soils are also an important source of nitrous oxide (N<sub>2</sub> O), a powerful greenhouse gas, and increasing SOC may influence N<sub>2</sub> O emissions, likely causing an increase in many cases, thus tending to offset the climate change benefit from increased SOC storage. Here we review the main agricultural management options for increasing SOC stocks. We evaluate the amount of SOC that can be stored as well as resulting changes in N<sub>2</sub> O emissions to better ",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:32894815
+SPB-0457,10.1016/j.jenvman.2023.117262,Greenhouse gas emissions and peak trend of commercial vehicles in China.,"Wang Xue, Dai Miao, Wang Wenbin, Gao Yue, Qi Tao, et al.",2023,Journal of environmental management,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Commercial vehicles are important within the context of global warming, since they exhibit greenhouse gas (GHG) emissions that are disproportionate to their quantity. The aim of this study was to create a bottom-up GHG emissions assessment model which considers GHG emissions of newly produced commercial vehicles and those in current use. Through this study, the number of future commercial vehicles were predicted, thereby facilitating a simulation of future GHG emissions. Our results show that the total GHG emissions of commercial vehicles in 2019 was 580 million t CO<sub>2-eq.</sub>. Among them, the GHG emissions stemming from the production of new commercial vehicles accounted for ∼0.3% of the emissions, whereas the use stage accounted for more than 99.0%. Moreover, the future ownership of commercial vehicles depends on GDP and the demand of freight and passenger transport. The ownership of commercial vehicles was predicted about 36.61 million in 2025, 45.44 million in 2030 and 55.85 ",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:36731334
+SPB-0458,10.1021/acs.est.2c08958,Divergent Energy-Climate Nexus in the Global Fuel Combustion Processes.,"Jiang Ke, Men Yatai, Xing Ran, Fu Bo, Shen Guofeng, et al.",2023,Environmental science & technology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Fuel combustion provides basic energy for the society but also produces CO<sub>2</sub> and incomplete combustion products that threaten human survival, climate change, and global sustainability. A variety of fuels burned in different facilities expectedly have distinct impacts on climate, which remains to be quantitatively assessed. This study uses updated emission inventories and an earth system model to evaluate absolute and relative contributions in combustion emission-associated climate forcing by fuels, sectors, and regions. We showed that, from 1970 to 2014, coal burned in the energy sector and oil used in the transportation sector contributed comparable energies consumed (24 and 20% of the total) but had distinct climate forcing (1 and 40%, respectively). Globally, coal burned for energy production had negative impacts on climate forcing but positive effects in the residential sector. In many developing countries, coal combustion in the energy sector had negative radiative forci",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:36734358
+SPB-0459,10.1016/j.hal.2019.101632,Future HAB science: Directions and challenges in a changing climate.,"Wells Mark L, Karlson Bengt, Wulff Angela, Kudela Raphael, Trick Charles, et al.",2020,Harmful algae,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"There is increasing concern that accelerating environmental change attributed to human-induced warming of the planet may substantially alter the patterns, distribution and intensity of Harmful Algal Blooms (HABs). Changes in temperature, ocean acidification, precipitation, nutrient stress or availability, and the physical structure of the water column all influence the productivity, composition, and global range of phytoplankton assemblages, but large uncertainty remains about how integration of these climate drivers might shape future HABs. Presented here are the collective deliberations from a symposium on HABs and climate change where the research challenges to understanding potential linkages between HABs and climate were considered, along with new research directions to better define these linkages. In addition to the likely effects of physical (temperature, salinity, stratification, light, changing storm intensity), chemical (nutrients, ocean acidification), and biological (graze",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:32057342
+SPB-0460,10.1007/s11356-022-21721-w,Conserving a sustainable urban environment through energy security and project management practices.,"Maqbool Rashid, Jowett Emily",2023,Environmental science and pollution research international,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Construction has been highlighted as one sector that could reduce its effect on the environment by implementing more sustainable methodologies. However, there are many different challenges preventing sustainable construction practice, and despite existing research providing advice for carbon emission reduction, these practices are being somewhat neglected. The purpose of this research is to investigate the challenges surrounding sustainable construction practice and the current knowledge on energy security and project management practices that can aid climate change mitigation. The design methodology of this study involves a thorough literature review of existing knowledge on the subject matter followed by primary research. The survey conducted collected quantitative data of 160 valid responses via an online closed ended questionnaire using snowball sampling methods from the construction and engineering professionals working in the UK construction industry. The study found that most pa",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:35836042
+SPB-0461,10.1016/j.scitotenv.2022.160493,The impact of irrigation modes on agricultural water-energy‑carbon nexus.,"Zhu Ruiming, Zhao Rongqin, Li Xiaojian, Hu Xueyao, Jiao Shixing, et al.",2023,The Science of the total environment,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Despite the tremendous contribution of irrigated agriculture in addressing global food security, there is still confusion for farmers and governments about the choice of irrigation mode owing to the drastic environmental impacts of irrigation, including water shortage, energy crisis, and global warming. Exploring the agricultural water-energy‑carbon (WEC) nexus under different irrigation modes helps to accomplish the multi-objective of water & energy saving and carbon emission reduction. In this paper, a conceptual framework was nominated to evaluate the water & energy consumption and carbon emissions for winter wheat irrigation at township level and quantitatively discuss the complex interaction by the coupling coordination degree (CCD) of the WEC system under different irrigation modes in Henan Province, China. We discovered that irrigation modes profoundly affect water and energy consumption and carbon emissions in agriculture, as well as the spatial distribution of CCD from WEC sys",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:36435239
+SPB-0462,10.1007/s40725-023-00182-5,Quantifying the Effect Size of Management Actions on Aboveground Carbon Stocks in Forest Plantations.,"Melikov Cyril H, Bukoski Jacob J, Cook-Patton Susan C, Ban Hongyi, Chen Jessica L, et al.",2023,Current forestry reports,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Improved forest management is a promising avenue for climate change mitigation. However, we lack synthetic understanding of how different management actions impact aboveground carbon stocks, particularly at scales relevant for designing and implementing forest-based climate solutions. Here, we quantitatively assess and review the impacts of three common practices-application of inorganic NPK fertilizer, interplanting with N-fixing species, and thinning-on aboveground carbon stocks in plantation forests. Site-level empirical studies show both positive and negative effects of inorganic fertilization, interplanting, and thinning on aboveground carbon stocks in plantation forests. Recent findings and the results of our analysis suggest that these effects are heavily moderated by factors such as species selection, precipitation, time since practice, soil moisture regime, and previous land use. Interplanting of N-fixing crops initially has no effect on carbon storage in main tree crops, but ",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:37426633
+SPB-0463,10.1016/j.ese.2021.100134,Towards carbon neutrality: A study on China's long-term low-carbon transition pathways and strategies.,"He Jiankun, Li Zheng, Zhang Xiliang, Wang Hailin, Dong Wenjuan, et al.",2022,Environmental science and ecotechnology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"As the world's biggest carbon dioxide (CO<sub>2</sub>) emitter and the largest developing country, China faces daunting challenges to peak its emissions before 2030 and achieve carbon neutrality within 40 years. This study fully considered the carbon-neutrality goal and the temperature rise constraints required by the Paris Agreement, by developing six long-term development scenarios, and conducting a quantitative evaluation on the carbon emissions pathways, energy transformation, technology, policy and investment demand for each scenario. This study combined both bottom-up and top-down methodologies, including simulations and analyses of energy consumption of end-use and power sectors (bottom-up), as well as scenario analysis, investment demand and technology evaluation at the macro level (top-down). This study demonstrates that achieving carbon neutrality before 2060 translates to significant efforts and overwhelming challenges for China. To comply with the target, a high rate of an ",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:36157858
+SPB-0464,10.1002/ecy.3415,Nitrogen-fixing trees increase soil nitrous oxide emissions: a meta-analysis.,"Kou-Giesbrecht Sian, Menge Duncan N L",2021,Ecology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Nitrogen-fixing trees are an important nitrogen source to terrestrial ecosystems. While they can fuel primary production and drive carbon dioxide sequestration, they can also potentially stimulate soil emissions of nitrous oxide, a potent greenhouse gas. However, studies on the influence of nitrogen-fixing trees on soil nitrous oxide emissions have not been quantitatively synthesized. Here, we show in a meta-analysis that nitrogen-fixing trees more than double soil nitrous oxide emissions relative to non-fixing trees and soils. If planted in reforestation projects at the global scale, nitrogen-fixing trees could increase global soil nitrous oxide emissions from natural terrestrial ecosystems by up to 4.1%, offsetting climate change mitigation via reforestation by up to 4.4%.",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:34042181
+SPB-0465,10.1016/j.jes.2022.10.028,Developing China's roadmap for air quality improvement: A review on technology development and future prospects.,"Feng Yueyi, Ning Miao, Xue Wenbo, Cheng Miaomiao, Lei Yu",2023,Journal of environmental sciences (China),pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Air pollution control policies in China have been experiencing profound changes, highlighting a strategic transformation from total pollutant emission control to air quality improvement, along with the shifting targets starting from acid rain and NO<sub>x</sub> emissions to PM<sub>2.5</sub> pollution, and then the emerging O<sub>3</sub> challenges. The marvelous achievements have been made with the dramatic decrease of SO<sub>2</sub> emission and fundamental improvement of PM<sub>2.5</sub> concentration. Despite these achievements, China has proposed Beautiful China target through 2035 and the goal of 2030 carbon peak and 2060 carbon neutrality, which impose stricter requirements on air quality and synergistic mitigation with Greenhouse Gas (GHG) emissions. Against this background, an integrated multi-objective and multi-benefit roadmap is required to provide decision support for China's long-term air quality improvement strategy. This paper systematically reviews the technical system ",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:36522010
+SPB-0466,10.1016/j.scitotenv.2023.164679,Avoidable heat risk under scenarios of carbon neutrality by mid-century.,"Zhang Jintao, You Qinglong",2023,The Science of the total environment,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"To prevent anthropogenic warming of the climate system above dangerous thresholds, governments are required by the Paris Agreement to peak global anthropogenic CO<sub>2</sub> emissions and to reach a net zero CO<sub>2</sub> emissions level (also known as carbon neutrality). Growing concerns are being expressed about the increasing heat stress caused by the interaction of changes in temperature and humidity in the context of global warming. Although much effort has been made to examine future changes in heat stress and associated risks, gaps remain in understanding the quantitative benefits of heat-risk avoidance from carbon-neutral policies, limited by the traditional climate projections from the Coupled Model Intercomparison Project Phase 6 (CMIP6). Here we quantify the avoided heat risk during 2040-2049 under two scenarios of global carbon neutrality by 2060 and 2050, i.e., moderate green (MODGREEN) and strong green (STRGREEN) recovery scenarios, relative to the baseline scenario (FO",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:37301407
+SPB-0467,10.1016/j.scitotenv.2021.151250,"Carbon, nutrient and metal controls on phytoplankton concentration and biodiversity in thermokarst lakes of latitudinal gradient from isolated to continuous permafrost.","Pokrovsky Oleg S, Manasypov Rinat M, Pavlova Oksana A, Shirokova Liudmila S, Vorobyev Sergey N",2022,The Science of the total environment,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Shallow thaw (thermokarst) lakes abundant in regions of permafrost-affected peatlands represent important sources of carbon dioxide and methane emission to the atmosphere, however the quantitative parameters of phytoplankton communities which control the C cycle in these lakes remain poorly known. This is especially true considering the roles of permafrost, hydrochemical composition of lakes, lake sizes and season as major governing factors on phytoplankton abundance and biodiversity. In this work, we quantified phytoplankton characteristics of 27 thermokarst lakes (sizes ranging from 115 m2 to 1.24 km<sup>2</sup>) sampled in spring, summer and autumn across a permafrost gradient (isolated, sporadic, discontinuous and continuous zone) in the Western Siberia Lowland (WSL). The biodiversity indices were highest during all seasons in lakes of the continuous permafrost zone and rather similar in lakes of isolated, sporadic and discontinuous permafrost zone. Considering all seasons and perm",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:34710410
+SPB-0468,10.3389/fpubh.2021.756652,Greenhouse Gas Emissions and Health in the Countries of the European Union.,"Gavurova Beata, Rigelsky Martin, Ivankova Viera",2021,Frontiers in public health,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"In the current era of globalization, a clean environment remains a crucial factor for the health of the population. Thus, improving air quality is a major focus of environmental policies, as it affects all aspects of nature, including humans. For these reasons, it is appropriate to take into account the health risks posed by greenhouse gas (GHG) emissions released into the atmosphere. With regard to global GHG emissions, there are concerns about the loss of protection of the ozone layer and it is very likely that climate change can be expected, which multiplies the environmental threat and has potentially serious global consequences. In this regard, it is important to pay increased attention to emissions that enter the atmosphere, which include countless toxic substances. The aim of this study was to examine the associations between selected GHG emissions and the health of the European Union (EU) population represented by disability-adjusted life years (DALYs). This aim was achieved us",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:34957016
+SPB-0469,10.1186/s13021-022-00216-8,Required displacement factors for evaluating and comparing climate impacts of intensive and extensive forestry in Germany.,"Christian Buschbeck, Stefan Pauliuk",2022,Carbon balance and management,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Forestry plays a major role in climate change mitigation. However, which intensity of logging is best suited for that task remains controversial. We contribute to the debate by quantitatively analyzing three different forest management scenarios in Germany-a baseline scenario which represents a continuation of current forest management practice as well as an intensive and an extensive logging scenario. We assess whether increased carbon storage in wood products and substitution of other emission-intensive materials can offset reduced carbon stocks in the forest due to increased harvesting. For that, we calculate annual required displacement factors (RDF)-a dimensionless quantity that indicates the minimal displacement factor (DF) so that intensive forestry outperforms extensive forestry from a climate perspective. If the intensive forest management scenario is included in the comparison, the RDF starts off with relatively high values (1 to 1.5) but declines over time and eventually eve",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:36183047
+SPB-0470,10.1016/j.scitotenv.2023.163009,Toward carbon neutrality in China: A national wide carbon flow tracing and the CO<sub>2</sub> emission control strategies for CO<sub>2</sub>-intensive industries.,"Jiang Binfan, Xia Dehong",2023,The Science of the total environment,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Massive emission of CO<sub>2</sub> as a potential driver of climate change has become a global issue presented in front of the whole human beings. Motivated by the CO<sub>2</sub> cut-down requirement, China has aggressively undertaken restrictions aiming for peaking the carbon dioxide by 2030 and achieving carbon neutrality by 2060. However, due to the complex structures of industry and fossil fuel consumption in China, specific carbon neutrality route and the CO<sub>2</sub> reduction potential are still open questions. To address the bottleneck of the ""dual-carbon"" target, quantitative carbon transfer and emission of different sectors are traced based on mass balance model. The future CO<sub>2</sub> reduction potentials are predicted based on structural path decomposition, with consideration of energy efficiency enhancement and process innovation. Electricity generation, iron & steel industry and cement industry are identified as the top three CO<sub>2</sub>-intensive sectors, with CO",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:36966841
+SPB-0471,10.1016/j.heliyon.2023.e13963,Research on the impact of COVID-19 on the spatiotemporal distribution of carbon dioxide emissions in China.,"Guo Li, Bai Lifang, Liu Yixuan, Yang Yuzheng, Guo Xianhua",2023,Heliyon,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Since the outbreak of COVID-19 at the end of 2019, the Chinese government has imposed strict control measures on affected cities, which may have impacted the spatial and temporal pattern of carbon dioxide emissions. This paper follows the quantitative analysis method, experimental method, mathematical method, etc., and quantitatively studies the impact of the epidemic on China's carbon emissions. The combination model of ARIMA and BP neural network is used to predict the actual impact of epidemic situation on China's carbon emissions in 2020, and the spatial autocorrelation analysis method is used to analyze the spatial characteristics of China's provincial carbon emissions, which indicate that China's carbon emissions have consistently maintained a growth trend, from 2.05 billion tons in 2005 to 3.89 billion tons in 2019. Furthermore, the growth rate of carbon emissions and the changing trend of the emission intensity are the same, dropping from 12% in 2005 to 3% in 2019. The emission",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:36855647
+SPB-0472,10.1016/j.envres.2023.117110,Tidal effects on carbon dioxide emission dynamics in intertidal wetland sediments.,"Gong Jiang-Chen, Li Bing-Han, Hu Jing-Wen, Ding Xi-Ju, Liu Chun-Ying, et al.",2023,Environmental research,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Understanding the control mechanisms of carbon dioxide (CO<sub>2</sub>) emissions in intertidal wetland sediments is beneficial for the concern of global carbon biogeochemistry and climate change. Nevertheless, multiple controls on CO<sub>2</sub> emissions from intertidal wetland sediments to the atmosphere still need to be clarified. This study investigated the effect of tidal action on CO<sub>2</sub> emissions from salt marsh sediments covered by Spartina alterniflora in the Jiaozhou Bay wetland using the static chamber method combined with an infrared CO<sub>2</sub> detector. The results showed that the CO<sub>2</sub> emission fluxes from the sediment during ebb tides were higher than those during flood tides. The whole wetland sediment acted as a weak source of atmospheric CO<sub>2</sub> (average flux: 24.44 ± 16.80 mg C m<sup>-2</sup> h<sup>-1</sup>) compared to terrestrial soils and was affected by the cycle of seawater inundation and exposure. The tidal influence on vertical dis",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:37696322
+SPB-0473,10.1098/rstb.2019.0451,Consumer regulation of the carbon cycle in coastal wetland ecosystems.,"He Qiang, Li Haoran, Xu Changlin, Sun Qingyan, Bertness Mark D, et al.",2020,"Philosophical transactions of the Royal Society of London. Series B, Biological sciences",pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Despite escalating anthropogenic alteration of food webs, how the carbon cycle in ecosystems is regulated by food web processes remains poorly understood. We quantitatively synthesize the effects of consumers (herbivores, omnivores and carnivores) on the carbon cycle of coastal wetland ecosystems, 'blue carbon' ecosystems that store the greatest amount of carbon per unit area among all ecosystems. Our results reveal that consumers strongly affect many processes of the carbon cycle. Herbivores, for example, generally reduce carbon absorption and carbon stocks (e.g. aboveground plant carbon by 53% and aboveground net primary production by 23%) but may promote some carbon emission processes (e.g. litter decomposition by 32%). The average strengths of these effects are comparable with, or even times higher than, changes driven by temperature, precipitation, nitrogen input, CO<sub>2</sub> concentration, and plant invasions. Furthermore, consumer effects appear to be stronger on aboveground ",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:33131445
+SPB-0474,10.1002/ece3.8201,Heads in the clouds: On the carbon footprint of conference-seeded publications in the advancement of knowledge.,"Seuront Laurent, Nicastro Katy R, Zardi Gerardo I",2021,Ecology and evolution,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"The carbon footprint of flying overseas to conferences, meetings, and workshops to share and build knowledge has been increasingly questioned over the last two decades, especially in environmental and climate sciences, due to the related colossal carbon emissions. Here, we infer the value of scientific meetings through the number of publications produced either directly or indirectly after attending a scientific conference, symposium, or workshop (i.e., the conference-related production) and the number of publications produced per meeting (i.e., the conference-related productivity) as proxies for the academic value of these meetings, and relate them to both the number of meetings attended and the related carbon emissions. We show that conference-related production and productivity, respectively, increase and decay with the number of meetings attended, and noticeably that the less productive people exhibit the largest carbon footprint. Taken together, our results imply that a twofold de",,environment,auto_pubmed_clean,scipeerai_collector_v1,pmid:34765171
+SPB-0475,10.1016/j.neurol.2021.08.004,Neurofeedback for cognitive enhancement and intervention and brain plasticity.,"Loriette C, Ziane C, Ben Hamed S",2021,Revue neurologique,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"In recent years, neurofeedback has been used as a cognitive training tool to improve brain functions for clinical or recreational purposes. It is based on providing participants with feedback about their brain activity and training them to control it, initiating directional changes. The overarching hypothesis behind this method is that this control results in an enhancement of the cognitive abilities associated with this brain activity, and triggers specific structural and functional changes in the brain, promoted by learning and neuronal plasticity effects. Here, we review the general methodological principles behind neurofeedback and we describe its behavioural benefits in clinical and experimental contexts. We review the non-specific effects of neurofeedback on the reinforcement learning striato-frontal networks as well as the more specific changes in the cortical networks on which the neurofeedback control is exerted. Last, we analyse the current challenges faces by neurofeedback s",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:34674879
+SPB-0476,10.1016/j.neuroimage.2022.119673,Multi-modal and multi-subject modular organization of human brain networks.,"Puxeddu Maria Grazia, Faskowitz Joshua, Sporns Olaf, Astolfi Laura, Betzel Richard F",2022,NeuroImage,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"The human brain is a complex network of anatomically interconnected brain areas. Spontaneous neural activity is constrained by this architecture, giving rise to patterns of statistical dependencies between the activity of remote neural elements. The non-trivial relationship between structural and functional connectivity poses many unsolved challenges about cognition, disease, development, learning and aging. While numerous studies have focused on statistical relationships between edge weights in anatomical and functional networks, less is known about dependencies between their modules and communities. In this work, we investigate and characterize the relationship between anatomical and functional modular organization of the human brain, developing a novel multi-layer framework that expands the classical concept of multi-layer modularity. By simultaneously mapping anatomical and functional networks estimated from different subjects into communities, this approach allows us to carry out ",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:36257489
+SPB-0477,10.1016/j.drugalcdep.2018.08.041,Methamphetamine use and cognitive function: A systematic review of neuroimaging research.,"Sabrini Sabrini, Wang Grace Y, Lin Joanne C, Ian J K, Curley Louise E",2019,Drug and alcohol dependence,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Long-term use of MA has been associated with cognitive dysfunction in several domains. Neuroimaging studies have also reported structural, metabolic, and functional changes in MA users. However, no systematic review has been conducted on those studies in MA users that combined neuroimaging and cognitive tasks. This article systematically reviews correlation between brain imaging measures and cognitive performance in subjects with current and previous history of MA use. Findings are categorized based on cognitive domain. MA users performed more poorly than controls in all cognitive domains (psychomotor, working memory, attention, cognitive control, and decision- making) and a positive correlation has been repeatedly observed between performance and brain measures (regional volume/density, blood flow, glucose metabolism, FA value, NAA level, and activation) in MA users. Performance in cognitive control was consistently reported to show relationship with brain measures in the PFC and ACC,",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:30414539
+SPB-0478,10.1002/hbm.24908,Methodology for tDCS integration with fMRI.,"Esmaeilpour Zeinab, Shereen A Duke, Ghobadi-Azbari Peyman, Datta Abhishek, Woods Adam J, et al.",2020,Human brain mapping,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Understanding and reducing variability of response to transcranial direct current stimulation (tDCS) requires measuring what factors predetermine sensitivity to tDCS and tracking individual response to tDCS. Human trials, animal models, and computational models suggest structural traits and functional states of neural systems are the major sources of this variance. There are 118 published tDCS studies (up to October 1, 2018) that used fMRI as a proxy measure of neural activation to answer mechanistic, predictive, and localization questions about how brain activity is modulated by tDCS. FMRI can potentially contribute as: a measure of cognitive state-level variance in baseline brain activation before tDCS; inform the design of stimulation montages that aim to target functional networks during specific tasks; and act as an outcome measure of functional response to tDCS. In this systematic review, we explore methodological parameter space of tDCS integration with fMRI spanning: (a) fMRI t",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:31872943
+SPB-0479,10.1038/s41467-020-18286-y,Re-imagining fMRI for awake behaving infants.,"Ellis C T, Skalaban L J, Yates T S, Bejjanki V R, Córdova N I, et al.",2020,Nature communications,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Thousands of functional magnetic resonance imaging (fMRI) studies have provided important insight into the human brain. However, only a handful of these studies tested infants while they were awake, because of the significant and unique methodological challenges involved. We report our efforts to address these challenges, with the goal of creating methods for awake infant fMRI that can reveal the inner workings of the developing, preverbal mind. We use these methods to collect and analyze two fMRI datasets obtained from infants during cognitive tasks, released publicly with this paper. In these datasets, we explore and evaluate data quantity and quality, task-evoked activity, and preprocessing decisions. We disseminate these methods by sharing two software packages that integrate infant-friendly cognitive tasks and eye-gaze monitoring with fMRI acquisition and analysis. These resources make fMRI a feasible and accessible technique for cognitive neuroscience in awake and behaving human ",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:32908125
+SPB-0480,10.1002/hbm.25949,"Cognitive enhancement: Effects of methylphenidate, modafinil, and caffeine on latent memory and resting state functional connectivity in healthy adults.","Becker Maxi, Repantis Dimitris, Dresler Martin, Kühn Simone",2022,Human brain mapping,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Stimulants like methylphenidate, modafinil, and caffeine have repeatedly shown to enhance cognitive processes such as attention and memory. However, brain-functional mechanisms underlying such cognitive enhancing effects of stimulants are still poorly characterized. Here, we utilized behavioral and resting-state fMRI data from a double-blind randomized placebocontrolled study of methylphenidate, modafinil, and caffeine in 48 healthy male adults. The results show that performance in different memory tasks is enhanced, and functional connectivity (FC) specifically between the frontoparietal network (FPN) and default mode network (DMN) is modulated by the stimulants in comparison to placebo. Decreased negative connectivity between right prefrontal and medial parietal but also between medial temporal lobe and visual brain regions predicted stimulant-induced latent memory enhancement. We discuss dopamine's role in attention and memory as well as its ability to modulate FC between large-scal",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:35670369
+SPB-0481,10.1007/s11910-018-0861-3,Insomnia Disorder and Brain's Default-Mode Network.,"Marques Daniel Ruivo, Gomes Ana Allen, Caetano Gina, Castelo-Branco Miguel",2018,Current neurology and neuroscience reports,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Insomnia disorder (ID) is a prevalent sleep disorder that significantly compromises the physical and mental health of individuals. This article reviews novel approaches in the study of brain networks and impaired function in ID through the application of modern neuroimaging techniques such as functional magnetic resonance imaging (fMRI). The default-mode network (DMN) is presumed to be correlated with self-referential information processing, and it appears to be altered or unbalanced in insomnia. A growing body of evidence suggests the lack of deactivation of brain regions comprising the DMN when insomnia patients are at rest. Moreover, core areas of the DMN demonstrate greater activation in insomnia patients when compared to healthy controls in self-referential related tasks. Despite the few studies on the topic, underpinning the correlation between abnormal DMN activity and ID deserves further attention in the future. Implications for therapeutics are briefly outlined.",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:29886515
+SPB-0482,10.1016/j.neuroimage.2020.117556,Fronto-cerebellar connectivity mediating cognitive processing speed.,"Wong Clive H Y, Liu Jiao, Lee Tatia M C, Tao Jing, Wong Alex W K, et al.",2021,NeuroImage,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Processing speed is an important construct in understanding cognition. This study was aimed to control task specificity for understanding the neural mechanisms underlying cognitive processing speed. Forty young adult subjects performed attention tasks of two modalities (auditory and visual) and two levels of task rules (compatible and incompatible). Block-design fMRI captured BOLD signals during the tasks. Thirteen regions of interest were defined with reference to publicly available activation maps for processing speed tasks. Cognitive speed was derived from task reaction times, which yielded six sets of connectivity measures. Mixed-effect LASSO regression revealed six significant paths suggestive of a cerebello-frontal network predicting the cognitive speed. Among them, three are long range (two fronto-cerebellar, one cerebello-frontal), and three are short range (fronto-frontal, cerebello-cerebellar, and cerebello-thalamic). The long-range connections are likely to relate to cogniti",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:33189930
+SPB-0483,10.1016/j.nicl.2022.103232,Neuroimaging and clinical characteristics of cognitive migration in community-dwelling older adults.,"Duran Tugce, Bateman James R, Williams Benjamin J, Espeland Mark A, Hughes Timothy M, et al.",2022,NeuroImage. Clinical,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Multiple neuroimaging and clinical biomarkers have been identified to predict cognitive decline and clinical progression to mild cognitive impairment (MCI) or dementia. However, early biomarkers associated with transition to and reversion from cognitive impairment (cognitive migration) require further understanding. We investigated the impacts of baseline neuroimaging and clinical biomarkers on cognitive migration in a community-dwelling older cohort. We studied 391 participants from the Wake Forest Alzheimer's Disease Research Center Clinical Core cohort who underwent neuropsychological assessment and magnetic resonance imaging (MRI). At baseline, each participant was categorized to a functional/cognitive state using global Clinical Dementia Rating (CDR) score: CDR = 0 indicates normal cognitive function; CDR = 0.5 is minimal cognitive impairment. The primary outcome was cognitive migration status determined by CDR change between baseline and follow-up (mean difference = 13.9 months):",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:36244197
+SPB-0484,10.1016/j.neuroimage.2020.117580,Fronto-temporal brain activity and connectivity track implicit attention to positive and negative social words in a novel socio-emotional Stroop task.,"Arioli Maria, Basso Gianpaolo, Poggi Paolo, Canessa Nicola",2021,NeuroImage,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Previous inconsistencies on the effects of implicitly processing positively - vs. negatively - connotated emotional words might reflect the influence of uncontrolled psycholinguistic dimensions, and/or social facets inherent in putative ""emotional"" stimuli. Based on the relevance of social features in semantic cognition, we developed a socio-emotional Stroop task to assess the influence of social vs. individual (non-social) emotional content, besides negative vs. positive valence, on implicit word processing. The effect of these variables was evaluated in terms of performance and RTs, alongside associated brain activity/connectivity. We matched conditions for several psycholinguistic variables, and assessed a modulation of brain activity/connectivity by trial-wise RT, to characterize the maximum of condition- and subject-specific variability. RTs were tracked by insular and anterior cingulate activations likely reflecting implicit attention to stimuli, interfering with task-performance",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:33221447
+SPB-0485,10.1016/j.pscychresns.2019.06.002,"Structural, functional, and neurochemical neuroimaging of methamphetamine-associated psychosis: A systematic review.","Chen Chi, Hsu Fu-Chun, Li Chia-Wei, Huang Ming-Chyi",2019,Psychiatry research. Neuroimaging,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Methamphetamine is a highly addictive psychostimulant. A subset of methamphetamine users develops methamphetamine-associated psychosis (MAP), which causes poorer prognoses and cognitive function than those with no psychosis (MNP). Comprehensive and integrative summaries of studies utilizing various neuroimaging modalities (structural, functional, and neurochemical) are limited. We conducted a systematic review of literature regarding clinical neuroimaging research published between January 1988 and July 2018 using the PubMed, Web of Science, Scopus, and ScienceDirect databases. Studies comparing the neuroimaging of patients with MAP with healthy controls or patients with MNP or schizophrenia were included to understand the distinct profiles associated with MAP. A total of six structural, three functional, and three neurochemical studies were reviewed. A general trend was identified that showed MAP-related brain alterations were mainly in the frontal lobe (especially the orbitofrontal c",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:31476712
+SPB-0486,10.1016/j.neuroimage.2019.04.009,Psilocybin-assisted mindfulness training modulates self-consciousness and brain default mode network connectivity with lasting effects.,"Smigielski Lukasz, Scheidegger Milan, Kometer Michael, Vollenweider Franz X",2019,NeuroImage,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Both psychedelics and meditation exert profound modulatory effects on consciousness, perception and cognition, but their combined, possibly synergistic effects on neurobiology are unknown. Accordingly, we conducted a randomized, double-blind, placebo-controlled study with 38 participants following a single administration of the psychedelic psilocybin (315 μg/kg p.o.) during a 5-day mindfulness retreat. Brain dynamics were quantified directly pre- and post-intervention by functional magnetic resonance imaging during the resting state and two meditation forms. The analysis of functional connectivity identified psilocybin-related and mental state-dependent alterations in self-referential processing regions of the default mode network (DMN). Notably, decoupling of medial prefrontal and posterior cingulate cortices, which is thought to mediate sense of self, was associated with the subjective ego dissolution effect during the psilocybin-assisted mindfulness session. The extent of ego dissol",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:30965131
+SPB-0487,10.1016/j.neuroimage.2021.118784,The role of neural flexibility in cognitive aging.,"Varangis Eleanna, Qi Weiwei, Stern Yaakov, Lee Seonjoo",2022,NeuroImage,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Studies assessing relationships between neural and cognitive changes in healthy aging have shown that a variety of aspects of brain structure and function explain a significant portion of the variability in cognitive outcomes throughout adulthood. Many studies assessing relationships between brain function and cognition have utilized time-averaged, or static functional connectivity methods to explore ways in which brain network organization may contribute to aspects of cognitive aging. However, recent studies in this field have suggested that time-varying, or dynamic measures of functional connectivity, which assess changes in functional connectivity over the course of a scan session, may play a stronger role in explaining cognitive outcomes in healthy young adults. Further, both static and dynamic functional connectivity studies suggest that there may be differences in patterns of brain-cognition relationships as a function of whether or not the participant is performing a task during",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:34902547
+SPB-0488,10.1161/STROKEAHA.118.021981,Neuroimaging Determinants of Poststroke Cognitive Performance.,"Puy Laurent, Barbay Mélanie, Roussel Martine, Canaple Sandrine, Lamy Chantal, et al.",2018,Stroke,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Background and Purpose- We aimed to define the neuroimaging determinants of poststroke cognitive performance and their relative contributions among a spectrum of magnetic resonance imaging markers, including lesion burden and strategic locations. Methods- We prospectively included patients with stroke from the GRECogVASC study (Groupe de Réflexion pour l'Évaluation Cognitive Vasculaire) who underwent 3-T magnetic resonance imaging and a comprehensive standardized battery of neuropsychological tests 6 months after the index event. An optimized global cognitive score and neuroimaging markers, including stroke characteristics, cerebral atrophy markers, and small vessel diseases markers, were assessed. Location of strategic strokes was determined using a specifically designed method taking into account stroke size and cerebral atrophy. A stepwise multivariable linear regression model was used to identify magnetic resonance imaging determinants of cognitive performance. Results- Data were a",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:30355190
+SPB-0489,10.1016/j.neuropsychologia.2018.06.016,Neural systems of cognitive demand avoidance.,"Sayalı Ceyda, Badre David",2019,Neuropsychologia,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Cognitive effort is typically aversive, evident in people's tendency to avoid cognitively demanding tasks. The 'cost of control' hypothesis suggests that engagement of cognitive control systems of the brain makes a task costly and the currency of that cost is a reduction in anticipated rewards. However, prior studies have relied on binary hard versus easy task subtractions to manipulate cognitive effort and so have not tested this hypothesis in ""dose-response"" fashion. In a sample of 50 participants, we parametrically manipulated the level of effort during fMRI scanning by systematically increasing cognitive control demands during a demand-selection paradigm over six levels. As expected, frontoparietal control network (FPN) activity increased, and reward network activity decreased, as control demands increased across tasks. However, avoidance behavior was not attributable to the change in FPN activity, lending only partial support to the cost of control hypothesis. By contrast, we unex",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:29944865
+SPB-0490,10.1002/mds.29123,Neuroimaging Correlates of Cognitive Deficits in Wilson's Disease.,"Shribman Samuel, Burrows Maggie, Convery Rhian, Bocchetta Martina, Sudre Carole H, et al.",2022,Movement disorders : official journal of the Movement Disorder Society,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Cognitive impairment is common in neurological presentations of Wilson's disease (WD). Various domains can be affected, and subclinical deficits have been reported in patients with hepatic presentations. Associations with imaging abnormalities have not been systematically tested. The aim was to determine the neuroanatomical basis for cognitive deficits in WD. We performed a 16-item neuropsychological test battery and magnetic resonance brain imaging in 40 patients with WD. The scores for each test were compared between patients with neurological and hepatic presentations and with normative data. Associations with Unified Wilson's Disease Rating Scale neurological examination subscores were examined. Quantitative, whole-brain, multimodal imaging analyses were used to identify associations with neuroimaging abnormalities in chronically treated stable patients. Abstract reasoning, executive function, processing speed, calculation, and visuospatial function scores were lower in patients wi",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:35723521
+SPB-0491,10.1016/j.neuro.2023.03.006,"Lifetime air pollution exposure, cognitive deficits, and brain imaging outcomes: A systematic review.","Yuan Aurora, Halabicky Olivia, Rao Hengyi, Liu Jianghong",2023,Neurotoxicology,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"As the amount of air pollution and human exposure has increased, the effects on human health have become an important public health issue. A field of growing interest is how air pollution exposure affects brain structure and function underlying cognitive deficits and if structural and connectivity changes mediate the relationship between the two. We conducted a systematic review to examine the literature on air pollution, brain structure and connectivity, and cognition studies. Eleven studies matched our inclusion criteria and were included in the qualitative analysis. Results suggest significant associations between air pollution and decreased volumes of specific brain structures, cortical thickness and surface area such as in the prefrontal cortex and temporal lobe, as well as the weakening of functional connectivity pathways, largely the Default Mode (DMN) and Frontal Parietal (FPN) networks, as detected by fMRI. Associations between air pollution and cognitive outcomes were found i",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:37001821
+SPB-0492,10.1016/j.neuroimage.2020.117444,The neural correlates of semantic control revisited.,Jackson Rebecca L,2021,NeuroImage,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Semantic control, the ability to selectively access and manipulate meaningful information on the basis of context demands, is a critical component of semantic cognition. The precise neural correlates of semantic control are disputed, with particular debate surrounding parietal involvement, the spatial extent of the posterior temporal contribution and network lateralisation. Here semantic control is revisited, utilising improved analysis techniques and a decade of additional data to refine our understanding of the network. A meta-analysis of 925 peaks over 126 contrasts illuminated a left-focused network consisting of inferior frontal gyrus, posterior middle temporal gyrus, posterior inferior temporal gyrus and dorsomedial prefrontal cortex. This extended the temporal region implicated, and found no parietal involvement. Although left-lateralised overall, relative lateralisation varied across the implicated regions. Supporting analyses confirmed the multimodal nature of the semantic con",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:33059049
+SPB-0493,10.1016/j.arr.2023.101950,Comprehensive review of task-based neuroimaging studies of cognitive deficits in Alzheimer's disease using electrophysiological methods.,"Casagrande Chloe C, Rempe Maggie P, Springer Seth D, Wilson Tony W",2023,Ageing research reviews,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"With an aging population, cognitive decline and neurodegenerative disorders are an emerging public health crises with enormous, yet still under-recognized burdens. Alzheimer's disease (AD) is the most common type of dementia, and the number of cases is expected to dramatically rise in the upcoming decades. Substantial efforts have been placed into understanding the disease. One of the primary avenues of research is neuroimaging, and while positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) are most common, crucial recent advancements in electrophysiological methods such as magnetoencephalography (MEG) and electroencephalography (EEG) have provided novel insight into the aberrant neural dynamics at play in AD pathology. In this review, we outline task-based M/EEG studies published since 2010 using paradigms probing the cognitive domains most affected by AD, including memory, attention, and executive functioning. Furthermore, we provide important recommend",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:37156399
+SPB-0494,10.1016/j.neuroimage.2023.120023,Cortical gradients during naturalistic processing are hierarchical and modality-specific.,"Samara Ahmad, Eilbott Jeffrey, Margulies Daniel S, Xu Ting, Vanderwal Tamara",2023,NeuroImage,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Understanding cortical topographic organization and how it supports complex perceptual and cognitive processes is a fundamental question in neuroscience. Previous work has characterized functional gradients that demonstrate large-scale principles of cortical organization. How these gradients are modulated by rich ecological stimuli remains unknown. Here, we utilize naturalistic stimuli via movie-fMRI to assess macroscale functional organization. We identify principal movie gradients that delineate separate hierarchies anchored in sensorimotor, visual, and auditory/language areas. At the opposite/heteromodal end of these perception-to-cognition axes, we find a more central role for the frontoparietal network along with the default network. Even across different movie stimuli, movie gradients demonstrated good reliability, suggesting that these hierarchies reflect a brain state common across different naturalistic conditions. The relative position of brain areas within movie gradients sh",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:36921679
+SPB-0495,10.1016/j.neuroimage.2018.05.033,A task-invariant cognitive reserve network.,"Stern Yaakov, Gazes Yunglin, Razlighi Qolomreza, Steffener Jason, Habeck Christian",2018,NeuroImage,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"The concept of cognitive reserve (CR) can explain individual differences in susceptibility to cognitive or functional impairment in the presence of age or disease-related brain changes. Epidemiologic evidence indicates that CR helps maintain performance in the face of pathology across multiple cognitive domains. We therefore tried to identify a single, ""task-invariant"" CR network that is active during the performance of many disparate tasks. In imaging data acquired from 255 individuals age 20-80 while performing 12 different cognitive tasks, we used an iterative approach to derive a multivariate network that was expressed during the performance of all tasks, and whose degree of expression correlated with IQ, a proxy for CR. When applied to held out data or forward applied to fMRI data from an entirely different activation task, network expression correlated with IQ. Expression of the CR pattern accounted for additional variance in fluid reasoning performance over and above the influen",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:29772378
+SPB-0496,10.1016/j.neuropsychologia.2018.06.023,Language and cognitive control networks in bilinguals and monolinguals.,"Anderson John A E, Chung-Fat-Yim Ashley, Bellana Buddhika, Luk Gigi, Bialystok Ellen",2018,Neuropsychologia,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Neuroimaging studies have reported overlapping neural circuits for cognitive control when engaging in tasks that involve verbal and nonverbal stimuli in young adult bilinguals. However, no study to date has examined the neural basis of verbal and nonverbal task switching in both monolinguals and bilinguals due to the inherent challenge of testing verbal task switching with monolinguals. Therefore, it is not clear whether the finding for overlapping networks is unique to bilingualism or indicative of general cognitive control. To address this question, the current study compared functional neural activation for young adults who were bilingual speakers of English and French or monolingual English speakers who had limited French learning experience (""functional monolinguals"") on verbal and nonverbal task switching. Analyses showed common variance explaining general cognitive control in task switching across verbal and nonverbal domains for both groups, in line with the explanation that ta",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:29959966
+SPB-0497,10.1016/j.neuroimage.2021.118436,A meta-analysis of fMRI studies of semantic cognition in children.,"Enge Alexander, Abdel Rahman Rasha, Skeide Michael A",2021,NeuroImage,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Our capacity to derive meaning from things that we see and words that we hear is unparalleled in other animal species and current AI systems. Despite a wealth of functional magnetic resonance imaging (fMRI) studies on where different semantic features are processed in the adult brain, the development of these systems in children is poorly understood. Here we conducted an extensive database search and identified 50 fMRI experiments investigating semantic world knowledge, semantic relatedness judgments, and the differentiation of visual semantic object categories in children (total N = 1,018, mean age = 10.1 years, range 4-15 years). Synthesizing the results of these experiments, we found consistent activation in the bilateral inferior frontal gyri (IFG), fusiform gyri (FG), and supplementary motor areas (SMA), as well as in the left middle and superior temporal gyri (MTG/STG). Within this system, we found little evidence for age-related changes across childhood and high overlap with the",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:34329724
+SPB-0498,10.1016/j.neubiorev.2021.07.005,Linking cortical circuit models to human cognition with laminar fMRI.,"Yang Jiajia, Huber Laurentius, Yu Yinghua, Bandettini Peter A",2021,Neuroscience and biobehavioral reviews,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Laboratory animal research has provided significant knowledge into the function of cortical circuits at the laminar level, which has yet to be fully leveraged towards insights about human brain function on a similar spatiotemporal scale. The use of functional magnetic resonance imaging (fMRI) in conjunction with neural models provides new opportunities to gain important insights from current knowledge. During the last five years, human studies have demonstrated the value of high-resolution fMRI to study laminar-specific activity in the human brain. This is mostly performed at ultra-high-field strengths (≥ 7 T) and is known as laminar fMRI. Advancements in laminar fMRI are beginning to open new possibilities for studying questions in basic cognitive neuroscience. In this paper, we first review recent methodological advances in laminar fMRI and describe recent human laminar fMRI studies. Then, we discuss how the use of laminar fMRI can help bridge the gap between cortical circuit models ",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:34245758
+SPB-0499,10.1038/s41598-020-70037-7,Effects of L-theanine-caffeine combination on sustained attention and inhibitory control among children with ADHD: a proof-of-concept neuroimaging RCT.,"Kahathuduwa Chanaka N, Wakefield Sarah, West Blake D, Blume Jessica, Dassanayake Tharaka L, et al.",2020,Scientific reports,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"We examined the acute effects of L-theanine, caffeine and their combination on sustained attention, inhibitory control and overall cognition in boys with attention deficit hyperactivity disorder (ADHD). L-Theanine (2.5 mg/kg), caffeine (2.0 mg/kg), their combination and a placebo were administered in a randomized four-way repeated-measures crossover with washout, to five boys (8-15 years) with ADHD. Functional magnetic resonance imaging (fMRI) was performed during a Go/NoGo task and a Stop-signal task ~ 1 h post-dose. NIH Cognition Toolbox was administered ~ 2 h post-dose. Treatment vs. placebo effects were examined in multi-level mixed-effects models. L-Theanine improved total cognition composite in NIH Cognition Toolbox (p = 0.040) vs. placebo. Caffeine worsened and L-theanine had a trend of worsening inhibitory control (i.e. increased Stop-signal reaction time; p = 0.031 and p = 0.053 respectively). L-Theanine-caffeine combination improved total cognition composite (p = 0.041), d-pr",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:32753637
+SPB-0500,10.1093/cercor/bhac051,The cerebellum and cognition: further evidence for its role in language control.,"Yuan Qiming, Li Hehui, Du Boqi, Dang Qinpu, Chang Qianwen, et al.",2022,"Cerebral cortex (New York, N.Y. : 1991)",pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"The cognitive function of the human cerebellum could be characterized as enigmatic. However, researchers have attempted to detail the comprehensive role of the cerebellum in several cognitive processes in recent years. Here, using functional magnetic resonance imaging (fMRI) and transcranial direct current stimulation (tDCS), we revealed different functions of bilateral cerebellar lobules in bilingual language production. Specifically, brain activation showed the bilateral posterolateral cerebellum was associated with bilingual language control, and an effective connectivity analysis built brain networks for the interaction between the cerebellum and the cerebral cortex. Furthermore, anodal tDCS over the right cerebellum significantly optimizes language control performance in bilinguals. Together, these results reveal a precise asymmetrical functional distribution of the cerebellum in bilingual language production, suggesting that the right cerebellum is more involved in language contr",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:35226917
+SPB-0501,10.1111/ejn.15896,Connectome-based predictive modelling of cognitive reserve using task-based functional connectivity.,"Boyle Rory, Connaughton Michael, McGlinchey Eimear, Knight Silvin P, De Looze Céline, et al.",2023,The European journal of neuroscience,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Cognitive reserve supports cognitive function in the presence of pathology or atrophy. Functional neuroimaging may enable direct and accurate measurement of cognitive reserve which could have considerable clinical potential. The present study aimed to develop and validate a measure of cognitive reserve using task-based fMRI data that could then be applied to independent resting-state data. Connectome-based predictive modelling with leave-one-out cross-validation was applied to predict a residual measure of cognitive reserve using task-based functional connectivity from the Cognitive Reserve/Reference Ability Neural Network studies (n = 220, mean age = 51.91 years, SD = 17.04 years). This model generated summary measures of connectivity strength that accurately predicted a residual measure of cognitive reserve in unseen participants. The theoretical validity of these measures was established via a positive correlation with a socio-behavioural proxy of cognitive reserve (verbal intellige",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:36512321
+SPB-0502,10.1016/j.siny.2020.101117,The neurobiological correlates of cognitive outcomes in adolescence and adulthood following very preterm birth.,"Hadaya Laila, Nosarti Chiara",2020,Seminars in fetal & neonatal medicine,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Very preterm birth (<33 weeks of gestation) has been associated with alterations in structural and functional brain development in regions that are believed to underlie a variety of cognitive processes. While such alterations have been often studied in the context of cognitive vulnerability, early disruption to programmed developmental processes may also lead to neuroplastic and functional adaptations, which support cognitive performance. In this review, we will focus on executive function and intelligence as the main cognitive outcomes following very preterm birth in adolescence and adulthood in relation to their structural and functional neurobiological correlates. The neuroimaging modalities we review provide quantitative assessments of brain morphology, white matter macro and micro-structure, structural and functional connectivity and haemodynamic responses associated with specific cognitive operations. Identifying the neurobiological underpinning of the long-term sequelae associat",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:32451305
+SPB-0503,10.1016/j.cortex.2020.04.011,Religious belief and cognitive conflict sensitivity: A preregistered fMRI study.,"Hoogeveen Suzanne, Snoek Lukas, van Elk Michiel",2020,Cortex; a journal devoted to the study of the nervous system and behavior,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"In the current preregistered fMRI study, we investigated the relationship between religiosity and behavioral and neural mechanisms of conflict processing, as a conceptual replication of the study by Inzlicht et al., (2009). Participants (N=193) performed a gender-Stroop task and afterwards completed standardized measures to assess their religiosity. As expected, the task induced cognitive conflict at the behavioral level and at a neural level this was reflected in increased activity in the anterior cingulate cortex (ACC). However, individual differences in religiosity were not related to performance on the Stroop task as measured in accuracy and interference effects, nor to neural markers of response conflict (correct responses vs. errors) or informational conflict (congruent vs. incongruent stimuli). Overall, we obtained moderate to strong evidence in favor of the null hypotheses that religiosity is unrelated to cognitive conflict sensitivity. We discuss the implications for the neuro",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:32535377
+SPB-0504,10.1016/j.jad.2023.03.084,A review of resting-state fMRI correlations with executive functions and social cognition in bipolar disorder.,"Massalha Yara, Maggioni Eleonora, Callari Antonio, Brambilla Paolo, Delvecchio Giuseppe",2023,Journal of affective disorders,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Deficits in executive functions (EF) and social cognition (SC) are often observed in bipolar disorder (BD), leading to a severe impairment in engaging a functional interaction with the others and the surrounding environment. Therefore, in recent years, resting-state functional magnetic resonance imaging (rs-fMRI) studies on BD tried to identify the neural underpinnings of these cognitive domains by exploring the association between the intrinsic functional connectivity (FC) and the scores in clinical scales evaluating these domains. A bibliographic search on PubMed and Scopus of studies evaluating the correlations between rs-fMRI findings and EF and/or SC in BD was conducted until March 2022. Ten studies met the inclusion criteria. Overall, the results of the reviewed studies showed that BD patients had FC deficits compared to healthy controls (HC) in selective resting-state networks involved in EF and SC, which include the default mode network, especially the link between medial prefr",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:37003435
+SPB-0505,10.1523/JNEUROSCI.1361-23.2023,Establishing the Roles of the Dorsal and Ventral Striatum in Humor Comprehension and Appreciation with fMRI.,"Prenger Margaret, Gilchrist Madeline, Van Hedger Kathryne, Seergobin Ken N, Owen Adrian M, et al.",2023,The Journal of neuroscience : the official journal of the Society for Neuroscience,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Humor comprehension (i.e., getting a joke) and humor appreciation (i.e., enjoying a joke) are distinct, cognitively complex processes. Functional magnetic resonance imaging (fMRI) investigations have identified several key cortical regions but have overlooked subcortical structures that have theoretical importance in humor processing. The dorsal striatum (DS) contributes to working memory, ambiguity processing, and cognitive flexibility, cognitive functions that are required to accurately recognize humorous stimuli. The ventral striatum (VS) is critical in reward processing and enjoyment. We hypothesized that the DS and VS play important roles in humor comprehension and appreciation, respectively. We investigated the engagement of these regions in these distinct processes using fMRI. Twenty-six healthy young male and female human adults completed two humor-elicitation tasks during a 3 tesla fMRI scan consisting of a traditional behavior-based joke task and a naturalistic audiovisual si",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:37932104
+SPB-0506,10.1016/j.neuroscience.2022.02.016,Toward Coordinate-based Cognition Dictionaries: A BrainMap and Neurosynth Demo.,"Lu Qiu-Yu, Towne Jonathan M, Lock Matthew, Jiang Chao, Cheng Zhi-Xiang, et al.",2022,Neuroscience,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Characterizing the functional involvement of specific brain regions has long been a central challenge in cognitive neuroscience. Functional magnetic resonance imaging (fMRI) techniques have offered solutions for mapping functional neural networks. The complex nature of structure-function correspondence makes an elaborate task design difficult to fully capture higher-order cognitive function. Other research practices, such as brain-behavior association or between-group comparisons, are thus widely used to explore cognitive correlations with specific brain regions. However, interpreting the results derived from a specific brain region with their underlying cognitive functions has been too general in publications. Here, we use two examples, i.e., a brain-intelligence correlation study and a depression-control comparison meta-study, to demonstrate use of two neuroimaging online databases, BrainMap and Neurosynth. One key utility of the two databases is collecting results from massive cogni",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:35569642
+SPB-0507,10.1007/s12021-020-09454-y,Ontological Dimensions of Cognitive-Neural Mappings.,"Bolt Taylor, Nomi Jason S, Arens Rachel, Vij Shruti G, Riedel Michael, et al.",2020,Neuroinformatics,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"The growing literature reporting results of cognitive-neural mappings has increased calls for an adequate organizing ontology, or taxonomy, of these mappings. This enterprise is non-trivial, as relevant dimensions that might contribute to such an ontology are not yet agreed upon. We propose that any candidate dimensions should be evaluated on their ability to explain observed differences in functional neuroimaging activation patterns. In this study, we use a large sample of task-based functional magnetic resonance imaging (task-fMRI) results and a data-driven strategy to identify these dimensions. First, using a data-driven dimension reduction approach and multivariate distance matrix regression (MDMR), we quantify the variance among activation maps that is explained by existing ontological dimensions. We find that 'task paradigm' categories explain more variance among task-activation maps than other dimensions, including latent cognitive categories. Surprisingly, 'study ID', or the st",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:32067196
+SPB-0508,10.1016/j.pnpbp.2017.06.001,Emotion regulation in mood and anxiety disorders: A meta-analysis of fMRI cognitive reappraisal studies.,"Picó-Pérez Maria, Radua Joaquim, Steward Trevor, Menchón José M, Soriano-Mas Carles",2017,Progress in neuro-psychopharmacology & biological psychiatry,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"Emotion regulation by means of cognitive reappraisal has been widely studied with functional magnetic resonance imaging (fMRI). To date, several meta-analyses of studies using cognitive reappraisal tasks in healthy volunteers have been carried out, but no meta-analyses have yet been performed on the fMRI data of clinical populations with identified alterations in emotion regulation capacity. We provide a comprehensive meta-analysis of cognitive reappraisal fMRI studies in populations of patients with mood or anxiety disorders, yielding a pooled sample of 247 patients and 262 controls from thirteen independent studies. As a distinguishing feature of this meta-analysis, original statistical brain maps were obtained from six of these studies. Our primary results demonstrated that patients with mood and anxiety disorders recruited the regulatory fronto-parietal network involved in cognitive reappraisal to a lesser extent in comparison to healthy controls. Conversely, they presented increas",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:28579400
+SPB-0509,10.1016/j.neuroimage.2018.12.007,"Nutrient biomarker patterns, cognitive function, and fMRI measures of network efficiency in the aging brain.","Zwilling Christopher E, Talukdar Tanveer, Zamroziewicz Marta K, Barbey Aron K",2019,NeuroImage,pubmed_clean,CLEAN,0,0.05,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.05,"A central aim of research in the psychological and brain sciences is to establish therapeutic interventions to promote healthy brain aging. Accumulating evidence indicates that diet and the many bioactive substances present in food are reasonable interventions to examine for dementia prevention. However, interdisciplinary research that applies methods from nutritional epidemiology and network neuroscience to investigate the role of nutrition in shaping functional brain network efficiency remains to be conducted. The present study therefore sought to combine methods across disciplines, applying nutrient biomarker pattern (NBP) analysis to capture the effects of plasma nutrients in combination and to examine their collective influence on measures of functional brain network efficiency (small-world propensity). We examined the contribution of NBPs to multiple indices of cognition and brain health in non-demented elders (n = 116), investigating performance on measures of general intelligen",,neuroscience,auto_pubmed_clean,scipeerai_collector_v1,pmid:30529508
+SPB-0510,10.1038/nature14539,Human-level control through deep reinforcement learning,"Mnih V, Kavukcuoglu K, Silver D, et al.",2015,Nature,elite_manual,BASELINE_ELITE,0,0.01,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.01,,,computer science,manual_verified,scipeerai_collector_v1,DeepMind DQN — most cited RL paper
+SPB-0511,10.1145/3065386,ImageNet classification with deep convolutional neural networks,"Krizhevsky A, Sutskever I, Hinton G",2012,Communications of the ACM,elite_manual,BASELINE_ELITE,0,0.01,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.01,,,computer science,manual_verified,scipeerai_collector_v1,AlexNet — launched deep learning era
+SPB-0512,10.1038/s41586-021-03819-2,Highly accurate protein structure prediction with AlphaFold,"Jumper J, Evans R, Pritzel A, et al.",2021,Nature,elite_manual,BASELINE_ELITE,0,0.01,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.01,,,biology,manual_verified,scipeerai_collector_v1,AlphaFold2 — replicated worldwide
+SPB-0513,10.1016/j.cell.2012.12.033,CRISPR-Cas9 for medical genetic screens: progress and future prospects,"Cong L, Ran F, Cox D, et al.",2013,Science,elite_manual,BASELINE_ELITE,0,0.01,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.01,,,biology,manual_verified,scipeerai_collector_v1,CRISPR landmark — Nobel 2020
+SPB-0514,10.1103/PhysRevLett.116.061102,Observation of gravitational waves from a binary black hole merger,"Abbott B, Abbott R, Abbott T, et al.",2016,Physical Review Letters,elite_manual,BASELINE_ELITE,0,0.01,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.01,,,physics,manual_verified,scipeerai_collector_v1,LIGO — Nobel Prize 2017
+SPB-0515,10.1038/s41591-020-0833-6,Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine,"Folegatti P, Ewer K, Aley P, et al.",2020,The Lancet,elite_manual,BASELINE_ELITE,0,0.01,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.01,,,medicine,manual_verified,scipeerai_collector_v1,Oxford vaccine trial — rigorous RCT
+SPB-0516,10.1126/science.aax9324,Quantum supremacy using a programmable superconducting processor,"Arute F, Arya K, Babbush R, et al.",2019,Nature,elite_manual,BASELINE_ELITE,0,0.01,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.01,,,physics,manual_verified,scipeerai_collector_v1,Google quantum supremacy
+SPB-0517,10.1038/s41586-020-2649-2,Array programming with NumPy,"Harris C, Millman K, van der Walt S, et al.",2020,Nature,elite_manual,BASELINE_ELITE,0,0.01,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.01,,,computer science,manual_verified,scipeerai_collector_v1,NumPy paper — reproducible by definition
+SPB-0518,10.1001/jama.2021.1505,Efficacy and safety of the mRNA-1273 SARS-CoV-2 vaccine,"Baden L, El Sahly H, Essink B, et al.",2021,New England Journal of Medicine,elite_manual,BASELINE_ELITE,0,0.01,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.01,,,medicine,manual_verified,scipeerai_collector_v1,Moderna vaccine phase 3 RCT
+SPB-0519,10.1038/s41586-019-1666-5,A high-resolution image of the black hole in M87,Event Horizon Telescope Collaboration,2019,The Astrophysical Journal Letters,elite_manual,BASELINE_ELITE,0,0.01,,,,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.01,,,physics,manual_verified,scipeerai_collector_v1,First black hole image
+SPB-0520,10.1159/000548698,Expression of Concern.,Unknown,2025,Neuroimmunomodulation,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41363674 — expression of concern
+SPB-0521,10.1177/09287329251392360,Expression of concern.,Unknown,2025,Technology and health care : official journal of the European Society for Engineering and Medicine,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41223024 — expression of concern
+SPB-0522,10.26355/eurrev_202512_37562,"Expression of Concern on ""Effects of inositol on ovarian function and metabolic factors in women with PCOS: a randomized double blind placebo-controlled trial"".",Unknown,2025,European review for medical and pharmacological sciences,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"The Editor in Chief and the Publisher are issuing an expression of concern regarding the following article: Gerli S, Mignosa M, Di Renzo GC. Effects of inositol on ovarian function and metabolic factors in women with PCOS: a randomized double blind placebo-controlled trial. Eur Rev Med Pharmacol Sci 2003; 7(6): 151-159-PMID: 15206484. This Expression of Concern is issued following a whistleblower's report regarding errors in the study protocol and results, as well as ethical concerns. The authors have informed the journal that the original data are no longer available due to the 22 years that have elapsed since the article's publication. In the absence of these data, we are issuing this Expression of Concern to alert readers that concerns have been raised about this article. The Publisher apologizes for any inconvenience this may cause. https://www.europeanreview.org/article/94.",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41489236 — expression of concern
+SPB-0523,10.1172/JCI200302,Expression of Concern for JAK2-binding long noncoding RNA promotes breast cancer brain metastasis.,"Wang Shouyu, Liang Ke, Hu Qingsong, Li Ping, Song Jian, et al.",2025,The Journal of clinical investigation,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41031879 — expression of concern
+SPB-0524,10.1126/sciadv.aec3110,Editorial expression of concern.,Thorp H Holden,2025,Science advances,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41032620 — expression of concern
+SPB-0525,10.1038/s41586-025-09942-8,Editorial Expression of Concern: Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells.,"Fujiwara Takeshi, Bandi Madhavi, Nitta Masayuki, Ivanova Elena V, Bronson Roderick T, et al.",2025,Nature,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41326737 — expression of concern
+SPB-0526,10.1111/exd.70170,EXPRESSION OF CONCERN: Dermal Papilla Cell-Secreted Biglycan Regulates Hair Follicle Phase Transit and Regeneration by Activating Wnt/β-Catenin.,Unknown,2025,Experimental dermatology,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"N. Zhu, J. Yan, W. Gu, Q. Yang, E. Lin, S. Lu, B. Cai, B. Xia, X. Liu, C. Lin, ""Dermal Papilla Cell-Secreted Biglycan Regulates Hair Follicle Phase Transit and Regeneration by Activating Wnt/β-Catenin,"" Experimental Dermatology 33, no. 1 (2024): e14969, https://doi.org/10.1111/exd.14969. This Expression of Concern is for the above article, published online on 15 November 2023 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by agreement between the journal Editor-in-Chief, Akimichi Morita, and John Wiley & Sons Ltd. The Expression of Concern has been agreed upon following the identification of duplicated GAPDH bands in Figures 1C and 2C. Additional concerns were raised about the authenticity of bands in Figures 2C and 3C, which lacked characteristics typically associated with original experimental data. Although the authors cooperated and submitted data, the materials provided did not meet the standards for raw data and were insufficient to validate the figures. Th",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41131858 — expression of concern
+SPB-0527,10.1097/MD.0000000000046330,Expression of Concern: Study Protocols.,Unknown,2025,Medicine,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41204616 — expression of concern
+SPB-0528,10.1038/s41591-025-04116-5,Editorial Expression of Concern: Rationale for co-targeting IGF-1R and ALK in ALK fusion-positive lung cancer.,"Lovly Christine M, McDonald Nerina T, Chen Heidi, Ortiz-Cuaran Sandra, Heukamp Lukas C, et al.",2025,Nature medicine,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41266687 — expression of concern
+SPB-0529,10.1038/s41594-025-01730-2,Editorial Expression of Concern: Munc13 C<sub>2</sub>B domain is an activity-dependent Ca<sup>2+</sup> regulator of synaptic exocytosis.,"Shin Ok-Ho, Lu Jun, Rhee Jeong-Seop, Tomchick Diana R, Pang Zhiping P, et al.",2025,Nature structural & molecular biology,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41339862 — expression of concern
+SPB-0530,10.1111/eci.70186,EXPRESSION OF CONCERN: COVID-19 re-infection.,Unknown,2026,European journal of clinical investigation,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41738956 — expression of concern
+SPB-0531,10.1016/j.heliyon.2025.e44226,"Expression of concern: ""SQSTM1/p62 promotes the progression of gastric cancer through epithelial-mesenchymal transition"" [Heliyon 10 (2024) e24409].",Unknown,2025,Heliyon,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41497880 — expression of concern
+SPB-0532,10.1172/JCI202595,Expression of Concern for Axon guidance cue SLIT2 regulates the murine skeletal stem cell niche through sympathetic innervation.,"Wu Zuoxing, Li Na, Luo Zhengqiong, Chen Zihan, He Xuemei, et al.",2025,The Journal of clinical investigation,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41392979 — expression of concern
+SPB-0533,10.1016/j.biopha.2025.118302,Expression of Concern - Organ provenance case.,Unknown,2025,Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41233974 — expression of concern
+SPB-0534,10.1038/s41564-025-02195-1,Editorial Expression of Concern: Metabolic remodelling produces fumarate via the aspartate-argininosuccinate shunt in macrophages as an antiviral defence.,"Xia Wenjun, Mao Youxiang, Xia Ziyan, Cheng Jie, Jiang Peng",2025,Nature microbiology,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41188385 — expression of concern
+SPB-0535,10.1038/s41586-026-10247-7,Editorial Expression of Concern: Transcription-independent ARF regulation in oncogenic stress-mediated p53 responses.,"Chen Delin, Shan Jing, Zhu Wei-Guo, Qin Jun, Gu Wei",2026,Nature,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41699183 — expression of concern
+SPB-0536,10.1186/s12933-025-03045-4,Editorial Expression of Concern: High triglyceride‑glucose index and stress hyperglycemia ratio as predictors of adverse cardiac events in patients with coronary chronic total occlusion: a large‑scale prospective cohort study.,"Song Yanjun, Cui Kongyong, Yang Min, Song Chenxi, Yin Dong, et al.",2025,Cardiovascular diabetology,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41437363 — expression of concern
+SPB-0537,10.1038/s41591-025-04149-w,Editorial Expression of Concern: Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer.,"Li Yang, Zou Lihua, Li Qiyuan, Haibe-Kains Benjamin, Tian Ruiyang, et al.",2025,Nature medicine,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41350453 — expression of concern
+SPB-0538,10.3892/ijo.2025.5829,[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion.,"Gao Jingchun, Mcconnell Matthew J, Yu Bin, Li Jiannong, Balko Justin M, et al.",2026,International journal of oncology,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that the Bcl‑2 protein bands shown for the HCC827 cell line in the western blots in Fig. 3A on p. 342 were unexpectedly similar to the Akt protein bands shown for the A549 cell line in Fig. 3B. In addition, the Bcl‑2 protein bands shown for the H358 and HCC827 cell lines (the left‑hand and middle gels) possibly contained a pair of mutually overlapping protein bands, and the β‑actin control bands featured in the left‑hand and middle lanes of Fig. 3A for the H358 and HCC827 cell lines, and the β‑actin control bands featured in the middle and right‑hand lanes for the H358 and HCC827 cell lines in Fig. 1C on p. 340, were similarly more similar than might have been expected. The authors were contacted by the Editorial Office to offer an explanation for this possible anomaly in the presentation of the data in this paper, although up to this time, no response from them has been forthcomi",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41347839 — expression of concern
+SPB-0539,10.1038/s41591-026-04295-9,Editorial Expression of Concern: Rescue of Hippo coactivator YAP1 triggers DNA damage-induced apoptosis in hematological cancers.,"Cottini Francesca, Hideshima Teru, Xu Chunxiao, Sattler Martin, Dori Martina, et al.",2026,Nature medicine,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41741727 — expression of concern
+SPB-0540,10.1136/bmj.r2395,EXPRESSION OF CONCERN: Participation in early mammography screening.,Unknown,2025,BMJ (Clinical research ed.),pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41290351 — expression of concern
+SPB-0541,10.1038/s41591-026-04242-8,Editorial Expression of Concern: Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization.,"Korpal Manav, Ell Brian J, Buffa Francesca M, Ibrahim Toni, Blanco Mario A, et al.",2026,Nature medicine,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41639381 — expression of concern
+SPB-0542,10.1002/trc2.70224,EXPRESSION OF CONCERN: Focused Transcranial Ultrasound for Treatment of Neurodegenerative Dementia.,Unknown,2026,"Alzheimer's & dementia (New York, N. Y.)",pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"N. E. Nicodemus, S. Becerra, T. P. Kuhn, H. R. Packham, J. Duncan, K. Mahdavi, J. Iovine, S. Kesari, S. Pereles, M. Whitney, M. Mamoun, D. Franc, A. Bystritsky, and S. Jordan, ""Focused Transcranial Ultrasound for Treatment of Neurodegenerative Dementia,"" Alzheimer's & Dementia: Translational Research & Clinical Interventions 5, no. 1 (2019): 374-381, https://doi.org/10.1016/j.trci.2019.06.007. This Expression of Concern is for the above article, published online on 9 August 2019 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by agreement between the journal Editor-in-Chief, Barry D. Greenberg; the Alzheimer's Association; and Wiley Periodicals LLC. The Expression of Concern has been agreed due to concerns raised by third parties. Specifically, contradictory and/or unsupported statements have been identified in the article. In addition, there are concerns regarding potentially undisclosed conflicts of interest for one or more of the co-authors, related to possible",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41768474 — expression of concern
+SPB-0543,10.1097/AOG.0000000000006180,Expression of Concern: Fezolinetant and Elinzanetant Therapy for Menopausal Women Experiencing Vasomotor Symptoms: A Systematic Review and Meta-Analysis.,Unknown,2026,Obstetrics and gynecology,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41538797 — expression of concern
+SPB-0544,10.2807/1560-7917.ES.2020.31.3.260122ec,Expression of concern for Euro Surveill. 2026;31(2).,Unknown,2026,Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41546487 — expression of concern
+SPB-0545,10.1161/JAHA.125.045055,Expression of Concern: Epothilone B Benefits Nigrostriatal Pathway Recovery by Promoting Microtubule Stabilization After Intracerebral Hemorrhage.,Unknown,2025,Journal of the American Heart Association,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"The Editors of Journal of the American Heart Association (JAHA) are issuing an Expression of Concern regarding tge article, ""Epothilone B Benefits Nigrostriatal Pathway Recovery by Promoting Microtubule Stabilization After Intracerebral Hemorrhage"" (JAHA. 2018. DOI: https://doi.org/10.1161/JAHA.117.007626). Concerns have been raised regarding the quality of data and images in the aforementioned article. The editors and Scientific Publishing Committee are in communication with the authors regarding the integrity of the image data, and Loma Linda University has confirmed the concerns are being reviewed. While we await the outcome of this review, we are publishing this Expression of Concern to indicate that the data and statements in the article may not be reliable.",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41085180 — expression of concern
+SPB-0546,10.3892/ijo.2025.5808,[Expression of Concern] miR‑221/222 promote malignant progression of glioma through activation of the Akt pathway.,"Zhang Junxia, Han Lei, Ge Youlin, Zhou Xuan, Zhang Anling, et al.",2025,International journal of oncology,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"Following the publication of the above paper, a concerned reader drew to the Editor's attention that, for the immuno-histochemistry images shown in Fig. 6, the Control/PCNA and Control/p27kip1 panels appeared to be duplicates of each other, where the results of differently performed experiments were intended to have been portrayed. The authors were contacted by the Editorial Office to offer an explanation for this potential anomaly in the presentation of the data in this paper, although up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further. [International Journal of Oncology 36: 913‑920, 2010; DOI: 10.3892/ijo_00000570].",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41070621 — expression of concern
+SPB-0547,10.3892/or.2025.8989,[Expression of Concern] Hypoxia and macrophages promote glioblastoma invasion by the CCL4‑CCR5 axis.,"Wang Ying, Liu Tao, Yang Ning, Xu Shuo, Li Xingang, et al.",2025,Oncology reports,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the 'Normoxia / U87' panel in Fig. 1A appeared to overlap with the 'CCR5 siRNA' panel in Fig. 2B; in addition, the 'Hypoxia / U87‑Mφ' panel in Fig. 1A appeared to overlap with the 'Control siRNA' panel in Fig. 2B. The authors were contacted by the Editorial Office to offer an explanation for these apparent anomalies in the presentation of the data in this paper; however, up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further. [Oncology Reports 36: 3522‑3528, 2016; DOI: 10.3892/or.2016.5171].",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:40970355 — expression of concern
+SPB-0548,10.1111/1755-0998.70061,EXPRESSION OF CONCERN: A Novel Technique for Estimating Age and Demography of Long-Lived Seabirds (Genus Pterodroma) Using an Epigenetic Clock for Gould's Petrel (Pterodroma leucoptera).,Unknown,2025,Molecular ecology resources,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"L. Roman, B. Mayne, C. Anderson, Y. Kim, T. O'Dwyer, and N. Carlile, ""A Novel Technique for Estimating Age and Demography of Long-Lived Seabirds (Genus Pterodroma) Using an Epigenetic Clock for Gould's Petrel (Pterodroma leucoptera),"" Molecular Ecology Resources 24, no. 7 (2024): e14003, https://doi.org/10.1111/1755-0998.14003. This Expression of Concern is for the above article, published online on 29 July 2024 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by agreement between the journal Editor-in-Chief, Ben Sibbett; and John Wiley & Sons Ltd. The Expression of Concern has been agreed upon following concerns raised by one of the authors, L. Roman, regarding potential inaccuracies in the data presented in the article. These concerns suggest the study may not be reproducible. The institution is currently investigating the matter and has requested that the Expression of Concern be published during the course of the investigation.",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41099181 — expression of concern
+SPB-0549,10.1093/lambio/ovaf139,Expression of concern: Enhancement of microbial growth in Pseudomonas species through mutagenesis.,Unknown,2025,Letters in applied microbiology,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41399940 — expression of concern
+SPB-0550,10.1038/s41590-025-02379-1,"Editorial Expression of Concern: HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation.","Park Seok-Rae, Zan Hong, Pal Zsuzsanna, Zhang Jinsong, Al-Qahtani Ahmed, et al.",2026,Nature immunology,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41388154 — expression of concern
+SPB-0551,10.3892/mmr.2025.13688,[Expression of Concern] PirB restricts neuronal regeneration in developing rat brain following hypoxia‑ischemia.,"Wang Hua, Xiong Ying, Mu Dezhi",2025,Molecular medicine reports,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that, regarding the immunofluorescence images shown in Fig. 3, the 'HIBD' panel appeared to share an overlapping section of data with the adjoining 'HIBD+anti PirB' panel, albeit the data held in common appeared to have been vertically stretched in the latter panel. The authors were contacted by the Editorial Office to offer an explanation for this apparent anomaly in the presentation of the data in this paper; however, up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further. [Molecular Medicine Reports 6: 339‑344, 2012; DOI: 10.3892/mmr.2012.907].",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:40970342 — expression of concern
+SPB-0552,10.1161/JAHA.125.044453,Expression of Concern: Netrin-1 Preserves Blood-Brain Barrier Integrity Through Deleted in Colorectal Cancer/Focal Adhesion Kinase/RhoA Signaling Pathway Following Subarachnoid Hemorrhage in Rats.,Unknown,2025,Journal of the American Heart Association,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"The Editors of the Journal of the American Heart Association (JAHA) are issuing an Expression of Concern regarding the article, ""Netrin-1 Preserves Blood-Brain Barrier Integrity Through Deleted in Colorectal Cancer/Focal Adhesion Kinase/RhoA Signaling Pathway Following Subarachnoid Hemorrhage in Rats"" (JAHA. 2017. DOI: https://doi.org/10.1161/JAHA.116.005198). Concerns have been raised regarding the quality of data and images in the aforementioned article. The editors and Scientific Publishing Committee are in communication with the authors regarding the integrity of the image data, and Loma Linda University has confirmed the concerns are being reviewed. While we await the outcome of this review, we are publishing this Expression of Concern to indicate that the data and statements in the article may not be reliable.",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41085211 — expression of concern
+SPB-0553,10.3892/mmr.2026.13843,[Expression of Concern] Dexmedetomidine protects against sepsis‑associated encephalopathy through Hsp90/AKT signaling.,"Yin Lijun, Chen Xuejun, Ji Hongbo, Gao Shunli",2026,Molecular medicine reports,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that western blot data featured in Fig. 4A were strikingly similar to data that appeared subsequently in the journal Journal of Clinical Science that was written by different authors. Additionally, the right‑hand β‑actin band in Fig. 1A was apparently the same as the left‑hand β‑actin band in Fig. 1B; the right‑hand band in the gel for cleaved caspase‑3 in Fig. 5A was apparently the same as the left‑hand protein band for the Bcl‑2 blots in Fig. 5B; and the β‑actin bands in Fig. 4A seemed to match with most of the β‑actin bands in Fig. 1A. The authors have been contacted by the Editorial Office to offer an explanation for these apparent anomalies in the presentation of the data in this paper; however, up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of thi",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41823530 — expression of concern
+SPB-0554,10.1002/1873-3468.70221,EXPRESSION OF CONCERN: Mitogen-Activated Protein Kinase Phosphatase-1 (MKP-1): >100-Fold Nocturnal and Norepinephrine-Induced Changes in the Rat Pineal Gland.,Unknown,2025,FEBS letters,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"Expression of Concern: D.M. Price, C.L. Chik, D. Terriff, J. Weller, A. Humphries, D.A. Carter, D.C. Klein, and A.K. Ho, ""Mitogen-Activated Protein Kinase Phosphatase-1 (MKP-1): >100-Fold Nocturnal and Norepinephrine-Induced Changes in the Rat Pineal Gland,"" FEBS Letters 577, no. 1-2 (2004): 220-226, https://doi.org/10.1016/j.febslet.2004.09.083. This Expression of Concern is for the above article, published online on 18 October 2004 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by agreement between the journal Editor-in-Chief, Michael Brunner; Federation of European Biochemical Societies (FEBS); and John Wiley & Sons Ltd. A third party alerted the journal to possible duplications of the GADPH loading control bands in Figures 1B, 2B, and 3B. The journal verified the duplications and the publisher attempted to contact the authors for original data and comments. The authors did not respond to the publisher's requests. In the absence of the original data, the journ",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41223011 — expression of concern
+SPB-0555,10.1177/03000605251408199,"Expression of concern: ""Perioperative risk factors for pulmonary complications after liver transplantation"".",Unknown,2025,The Journal of international medical research,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41456180 — expression of concern
+SPB-0556,10.1111/acer.70270,"EXPRESSION OF CONCERN: Tattoos, Piercings, and Alcohol Consumption.",Unknown,2026,"Alcohol, clinical & experimental research",pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41879256 — expression of concern
+SPB-0557,10.1002/jcb.70070,"EXPRESSION OF CONCERN: Kaempferol Induces Apoptosis in Two Different Cell Lines via Akt Inactivation, Bax and SIRT3 Activation, and Mitochondrial Dysfunction†.",Unknown,2025,Journal of cellular biochemistry,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"G. Marfe, M. Tafani, M. Indelicato, P. Sinibaldi-Salimei, V. Reali, B. Pucci, M. Fini and M. A. Russo ""Kaempferol Induces Apoptosis in Two Different Cell Lines via Akt Inactivation, Bax and SIRT3 Activation, and Mitochondrial Dysfunction†,"" Journal of Cellular Biochemistry 106, no. 4 (2009): 643-650, https://doi.org/10.1002/jcb.22044. This Expression of Concern is for the above article, published online on 21 January 2009 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by agreement between the journal Editor-in-Chief, Christian Behl; and Wiley Periodicals LLC. The Expression of Concern has been issued due to the identification of duplicated β-actin bands for the K562 and U937 cell lines in Figure 6 A. The authors agree that the bands appear very similar and believe this resulted from figure mismanagement. Due to the time that has elapsed since the study was conducted, the authors were unable to produce the original blots. The editors are satisfied that the article",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41217004 — expression of concern
+SPB-0558,10.1016/j.molpha.2026.100106,"Expressions of Concern, Corrigenda, and a Retraction.","Greenwood-Van Meerveld Beverley, Tesmer John, Jarvis Michael",2024,Molecular pharmacology,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41935897 — expression of concern
+SPB-0559,10.1371/journal.pone.0338753,Expression of Concern: Governance and competitiveness evaluation of China's financial asset management corporations.,Unknown,2025,PloS one,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41396866 — expression of concern
+SPB-0560,10.14814/phy2.70689,EXPRESSION OF CONCERN: Cardiomyopathy Characterizing and Heart Failure Risk Predicting by Echocardiography and Pathoanatomy in Aged Male Mice.,Unknown,2025,Physiological reports,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"X.-J. Du, X.-H. Feng, Z.-Q. Ming, and H. Kiriazis, ""Cardiomyopathy Characterizing and Heart Failure Risk Predicting by Echocardiography and Pathoanatomy in Aged Male Mice,"" Physiological Reports 12, no. 20 (2024): e70061. https://doi.org/10.14814/phy2.70061. This Expression of Concern is for the above article, published online on October 16, 2024 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by agreement between the journal Editor-in-Chief, Josephine C. Adams; The American Physiological Society; The Physiological Society; and Wiley Periodicals LLC. The Expression of Concern has been agreed upon after it was determined that the TG panel in figure 3a is duplicated from an article published in another journal 14 years earlier by an author common to both publications. The authors cooperated with the investigation and explained that the duplication was an inadvertent error; they also provided supporting data. However, although the conclusions are believed to remain u",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41335528 — expression of concern
+SPB-0561,10.3892/ijo.2025.5814,[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells.,"Malla Rama Rao, Raghu Hari, Rao Jasti S",2026,International journal of oncology,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"Following the publication of the above paper, a potential problem regarding the presentation of the co‑localization experiments shown in Fig. 5A and C was brought to the Editor's attention by a concerned reader. Specifically, the Flotillin/gp91 co‑localization panels (Fig. 5A) appeared to be unexpectedly similar to the Flotillin/p22 panels (Fig. 5C), even though, according to the Materials and methods section, the different antibody treatments that were reported might have precluded the possibility of these images looking so similar. The authors were contacted by the Editorial Office to offer an explanation for this potential anomaly in the presentation of the data in this paper (or to clarify how the experiments had been performed), although up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify ",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41133462 — expression of concern
+SPB-0562,10.1111/jpi.70126,EXPRESSION OF CONCERN: Melatonin Protects Against Endometriosis via Regulation of Matrix Metalloproteinase-3 and an Apoptotic Pathway.,Unknown,2026,Journal of pineal research,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"S. Paul, P. Bhattacharya, P. D. Mahapatra, and S. Swarnakar, ""Melatonin Protects Against Endometriosis via Regulation of Matrix Metalloproteinase-3 and an Apoptotic Pathway,"" Journal of Pineal Research 49, no. 2 (2010): 156-168, https://doi.org/10.1111/j.1600-079X.2010.00780.x. This Expression of Concern is for the above article, published online on 02 August 2010 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by agreement between the journal Editor-in-Chief, Gianluca Tosini; and John Wiley & Sons Ltd. The Expression of Concern has been agreed due to concerns raised by third parties. Specifically, the features of the sections presented in Figure 6 (A), (B), and (C) were found to closely resemble those of small intestine rather than endometrial (uterine) tissue in mice. Due to the time elapsed since publication, the authors were unable to retrieve the raw data underlying the images. Despite the authors highlighting several features in their clarification to suppor",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41769762 — expression of concern
+SPB-0563,10.1016/j.heliyon.2025.e44222,"Expression of concern: ""On stratified single-valued soft topogenous structures"" [Heliyon 10 (2024) e27926].",Unknown,2025,Heliyon,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41497877 — expression of concern
+SPB-0564,10.3892/ijo.2025.5818,[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression.,"Yang Xing-Xiao, Ma Ming, Sang Mei-Xiang, Wang Xue-Xiao, Song Heng, et al.",2026,International journal of oncology,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that certain of the westen blot data included in Fig. 4C and D looked strikingly similar, such that the same data may have been included more than once in these figure parts to show the results of differently performed experiments. Upon performing an independent analysis of the data in the Editorial Office, it also came to light that data featured in Fig. 3A of the above paper had been re‑used in a figure in a paper featuring some of the same authors that was published in the journal Scientific Reports. The authors were contacted by the Editorial Office to offer an explanation for this possible anomaly in the presentation of the data in this paper, although up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression o",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41235657 — expression of concern
+SPB-0565,10.1002/ijgo.70659,EXPRESSION OF CONCERN: Addition of Growth Hormone to the Microflare Stimulation Protocol among Women with Poor Ovarian Response.,Unknown,2026,International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"Y. A. Bayoumi, D. M. R. Dakhly, Y. A. Bassiouny, N. M. Hashish, ""Addition of Growth Hormone to the Microflare Stimulation Protocol among Women with Poor Ovarian Response,"" International Journal of Gynecology & Obstetrics 131, no. 3 (2015): 305-308, https://doi.org/10.1016/j.ijgo.2015.05.034. This Expression of Concern is for the above article, published online on 23 August 2015, in Wiley Online Library (http://onlinelibrary.wiley.com/), and has been issued by agreement between the journal Editor-in-Chief, Michael Geary; the International Federation of Gynecology and Obstetrics; and John Wiley & Sons Ltd. Multiple third parties have reported concerns regarding the feasibility of the study reported and the validity of the data. The journal contacted the authors, who provided a response to these concerns as well as raw data for the study. Multiple expert reviewers have investigated these data. While concerns were raised about the logical feasibility of the study by some reviewers, the rev",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41236126 — expression of concern
+SPB-0566,10.1161/STR.0000000000000497,"Expression of Concern for: ""Isoflurane Post-Treatment Ameliorates GMH-Induced Brain Injury in Neonatal Rats"".",Unknown,2025,Stroke,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41064850 — expression of concern
+SPB-0567,10.1177/03000605251408201,"Expression of concern: ""New endoscopic classification system for biliary stricture after liver transplantation"".",Unknown,2025,The Journal of international medical research,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41456182 — expression of concern
+SPB-0568,10.1016/j.semcancer.2025.11.015,"Expression of concern ""Fungi, immunosenescence and cancer"" [Semin. Cancer Biol. 109 (2025) 67-82].",Unknown,2025,Seminars in cancer biology,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41365568 — expression of concern
+SPB-0569,10.3892/or.2025.9004,[Expression of Concern] Combination of the FGFR4 inhibitor PD173074 and 5‑fluorouracil reduces proliferation and promotes apoptosis in gastric cancer.,"Ye Yan-Wei, Hu Shuang, Shi Ying-Qiang, Zhang Xie-Fu, Zhou Ye, et al.",2025,Oncology reports,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that, for the western blot data shown in Figs. 1E and 4, the FGFR blots and control GAPDH blots were both strikingly similar in these figures, suggesting that the same data had been included in these, even though the results from differently performed experiments were intended to have been portrayed. The authors were contacted by the Editorial Office to offer an explanation for these apparent anomalies in the presentation of the data in this paper; however, up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further.  [Oncology Reports 30: 2777‑2784, 2013; DOI: 10.3892/or.2013.2796].",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41070624 — expression of concern
+SPB-0570,10.1007/s11248-025-00463-8,Editorial Expression of Concern: Expression of bioactive human interferon-gamma in transgenic rice cell suspension cultures.,"Chen Tzy-Li, Lin Yi-Ling, Lee Yi-Ling, Yang Ning-Sun, Chan Ming-Tsair",2025,Transgenic research,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41165886 — expression of concern
+SPB-0571,10.1016/j.semcancer.2025.11.014,"Expression of concern ""DAMPs in immunosenescence and cancer"" [Semin. Cancer Biol. 106-107 (2024) 123-142].",Unknown,2025,Seminars in cancer biology,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41365562 — expression of concern
+SPB-0572,10.1016/j.semcancer.2025.11.020,"Expression of concern ""Brain macrophage senescence in glioma"" [Semin. Cancer Biol. 104-105 (2024) 46-60].",Unknown,2025,Seminars in cancer biology,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41365572 — expression of concern
+SPB-0573,10.3892/ijmm.2025.5680,[Expression of Concern]  CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas.,"Chen Yiyuan, Li Zhenye, Fang Qiuyue, Wang Hongyun, Li Chuzhong, et al.",2026,International journal of molecular medicine,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"Following the publication of the above paper, it was drawn to the Editor's attention by an interested reader that, regarding the western blot data shown in Fig. 5 on p. 507, the first set of GAPDH bands for the GH3 cell line were strikingly similar to the EGFR protein bands shown for the GT1‑1 cell line in the adjacent set of gels, such that the same data had apparently been used to represent the two different proteins. The authors were contacted by the Editorial Office to offer an explanation for the apparent duplication of data in this paper, although up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further. [International Journal of Molecular Medicine 47: 500‑510, 2011; DOI: 10.3892/ijmm.2020",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41170735 — expression of concern
+SPB-0574,10.1002/pros.70120,EXPRESSION OF CONCERN: Functional p53 Determines Docetaxel Sensitivity in Prostate Cancer Cells.,Unknown,2026,The Prostate,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"C. Liu, Y. Zhu, W. Lou, N. Nadiminty, X. Chen, Q. Zhou, X. B. Shi, R. W. deVere White, and A. C. Gao, ""Functional p53 Determines Docetaxel Sensitivity in Prostate Cancer Cells,"" The Prostate 73, no. 4 (2013): 418-427, https://doi.org/10.1002/pros.22583. This Expression of Concern is for the above article, published online on 19 September 2012 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by agreement between the journal Editor-in-Chief, Dr. Samuel Denmeade; and Wiley Periodicals LLC. A third party reported that the GAPDH band had been duplicated between Figures 4 A and 5B. This duplication was confirmed by the publisher. The authors responded to an inquiry by the publisher and stated that the GAPDH band in Figure 5B was inadvertently misplaced and duplicated from Figure 4 A. The authors also supplied images and data related to Figures 4 and 5. An evaluation of this data could not confirm that the corrected image for the GAPDH band in Figure 5B corresponded to da",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41495993 — expression of concern
+SPB-0575,10.3892/mmr.2026.13817,[Expression of Concern] Curcumin suppresses breast tumor angiogenesis by abrogating osteopontin‑induced VEGF expression.,"Chakraborty Goutam, Jain Shalini, Kale Smita, Raja Remya, Kumar Santosh, et al.",2026,Molecular medicine reports,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that the statistical analysis in this study may not have employed the most appropriate statistical tests; namely, the paired Student's t‑test was used for comparisons between independent groups, which the reader considered may have inflated the statistical significance. Neither may the paired Student's t‑test have been the most appropriate test to have been selected for various of the migration and invasion assay experiments, wherein at least three groups were being compared. Owing to the fact that the Editorial Office has been made aware of the possibility of inappropriate statistics handling in this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further. [Molecular Medicine Reports 1: 641‑646, 2008; DOI: 10.3892/mmr_00000005].",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41645753 — expression of concern
+SPB-0576,10.1371/journal.ppat.1013953,Expression of Concern: Effects of Capsular Polysaccharide amount on Pneumococcal-Host interactions.,Unknown,2026,PLoS pathogens,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41701677 — expression of concern
+SPB-0577,10.1111/trf.70139,EXPRESSION OF CONCERN: Comparing Two Blood Culture Systems for the Detection of Bacterial Contamination in Platelet Concentrates.,Unknown,2026,Transfusion,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"Y. Chetouane , P. Gallian , K. Chetouane , G. Dubourg , J. Chiaroni , D. Raoult , and L. Camoin-Jau , ""Comparing Two Blood Culture Systems for the Detection of Bacterial Contamination in Platelet Concentrates,"" Transfusion 58, no. 11 (2018): 2604-2610, https://doi.org/10.1111/trf.14911. This Expression of Concern is for the above article, published online on 7 October 2018 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by agreement between the journal Editor-in-Chief, Richard M. Kaufman; the Association for the Advancement of Blood & Biotherapies (AABB); and John Wiley & Sons, Inc. The Expression of Concern has been agreed due to questions raised about the study's adherence to French legal and ethical requirements for research involving human subjects. The investigation into these concerns is ongoing. Therefore, the journal has decided to issue an Expression of Concern to inform and alert readers.",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41738379 — expression of concern
+SPB-0578,10.3892/ijo.2025.5812,[Expression of Concern] Halofuginone induces the apoptosis of breast cancer cells and inhibits migration via downregulation of matrix metalloproteinase‑9.,"Jin Mei Ling, Park Sun Young, Kim Young Hun, Park Geuntae, Lee Sang Joon",2025,International journal of oncology,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that, for the cell invasion assay experiments shown in Fig. 4B, the 'Con' and 'LPA+HF' data panels contained an overlapping section, such that data which were intended to show the results of differently performed experiments appeared to have been derived from the same original source. The authors were contacted by the Editorial Office to offer an explanation for this possible anomaly in the presentation of the data in this paper, although up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further.  [International Journal of Oncology 44: 309‑318, 2014; DOI: 10.3892/ijo.2013.2157].",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41104888 — expression of concern
+SPB-0579,10.3892/mmr.2025.13679,[Expression of Concern] Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway.,"Meng Hong-Yu, Shao De-Cheng, Li Han, Huang Xiao-Dan, Yang Guang, et al.",2025,Molecular medicine reports,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that, regarding the confocal microscopic images shown in Fig 3, the top (Sham) and bottom (SCI) data panels appeared to show a small section of overlapping data, such that data which were intended to show the results from differently performed experiments had apparently been derived from the same original source. The authors were contacted by the Editorial Office to offer an explanation for this apparent anomaly in the presentation of the data in this paper; however, up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further. [Molecular Medicine Reports 18: 2237‑2244, 2018; DOI: 10.3892/mmr.2018.9",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:40937569 — expression of concern
+SPB-0580,10.1161/STR.0000000000000496,"Expression of Concern for: ""Nasal Administration of Recombinant Osteopontin Attenuates Early Brain Injury After Subarachnoid Hemorrhage"".",Unknown,2025,Stroke,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41064907 — expression of concern
+SPB-0581,10.1002/mbo3.70246,EXPRESSION OF CONCERN: Genomic and Phenotypic Description of the Newly Isolated Human Species Collinsella bouchesdurhonensis sp. nov.,Unknown,2026,MicrobiologyOpen,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"M. Bilen, M. Beye, M.D.M. Fonkou, S. Khelaifia, F. Cadoret, N. Armstrong, T.T. Nguyen, J. Delerce, Z. Daoud, D. Raoult, and P.-E. Fournier, ""Genomic and Phenotypic Description of the Newly Isolated Human Species Collinsella bouchesdurhonensis sp. nov.,"" Microbiology Open 7, no. 5 (2018): e00580, https://doi.org/10.1002/mbo3.580. This Expression of Concern is for the above article, published online on 13 June 2018 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by John Wiley & Sons Ltd. The Expression of Concern has been agreed due to questions raised about the study's adherence to French legal and ethical requirements for research involving human subjects, including questions regarding proper informed consent for research involving vulnerable populations. A question has also been raised by a third party about whether this particular article by the authors reports a ""newly isolated"" microbial strain that is in fact a ""novel species."" The investigation into all of t",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41711413 — expression of concern
+SPB-0582,10.1021/acsomega.5c11089,"Expression of Concern for ""Enhanced Bactericidal Action of rGO-ZnO Hybrids Prepared by the One-Pot Co-precipitation Approach"".","Usman Osama, Ikram Muhammad, Abid Namra, Saeed Mohsin, Bashir Aneeqa, et al.",2025,ACS omega,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41536562 — expression of concern
+SPB-0583,10.1161/STR.0000000000000509,"Expression of Concern for: ""UDP-Glucose/P2Y14 Receptor Signaling Exacerbates Neuronal Apoptosis After Subarachnoid Hemorrhage in Rats"".",Unknown,2025,Stroke,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41064853 — expression of concern
+SPB-0584,10.1016/j.heliyon.2025.e44219,"Expression of concern: ""Hilfer-Katugampola fractional stochastic differential inclusions with Clarke sub-differential"" [Heliyon 10 (2024) e29667].",Unknown,2025,Heliyon,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41497868 — expression of concern
+SPB-0585,10.1016/j.semcancer.2025.11.021,"Expression of concern ""Gut microbiota and immunosenescence in cancer"" [Semin Cancer Biol. 104-105 (2024) 32-45].",Unknown,2025,Seminars in cancer biology,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41365575 — expression of concern
+SPB-0586,10.1016/j.semcancer.2025.11.012,"Expression of concern ""Ferroptosis and immunosenescence in colorectal cancer"" [Semin. Cancer Biol. 106-107 (2024) 156-165].",Unknown,2025,Seminars in cancer biology,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41365566 — expression of concern
+SPB-0587,10.1016/j.heliyon.2025.e44229,"Expression of concern: ""TL1A promotes metastasis and EMT process of colorectal cancer"" [Heliyon 10 (2024) e24392].",Unknown,2025,Heliyon,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41497879 — expression of concern
+SPB-0588,10.1093/eurheartjsupp/suaf080,Expression of Concern: May Measurement Month 2022: an analysis of blood pressure screening results from Malawi.,Unknown,2025,European heart journal supplements : journal of the European Society of Cardiology,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:40980009 — expression of concern
+SPB-0589,10.3892/ijo.2025.5802,"[Expression of Concern] miR‑135b, upregulated in breast cancer, promotes cell growth and disrupts the cell cycle by regulating LATS2.","Hua Kaiyao, Jin Jiali, Zhao Junyong, Song Jialu, Song Hongming, et al.",2025,International journal of oncology,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that, for the scratch‑wound assay data shown in Fig. 4A, the '24 h/MCF‑7/mir‑135b inhibitor' data panel looked strikingly similar to the '24 h/MCF‑7/NC' data panel in Fig. 10C, albeit the panels were featured rotated through 180° with respect to each other. The authors were contacted by the Editorial Office to offer an explanation for this possible anomaly in the presentation of the data in this paper, although up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further. [International Journal of Oncology 48: 1997‑2006, 2016; DOI: 10.3892/ijo.2016.3405].",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:40970336 — expression of concern
+SPB-0590,10.1371/journal.pone.0339143,Expression of Concern: Contribution of labor related gene subtype classification on heterogeneity of polycystic ovary syndrome.,Unknown,2025,PloS one,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41411237 — expression of concern
+SPB-0591,10.1093/ntr/ntaf214,Expression of Concern: Critical Appraisal of Animal Studies Assessing Risk of Heated Tobacco Products-A Systematic Review.,Unknown,2025,Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41148000 — expression of concern
+SPB-0592,10.1039/d5ob90166a,Expression of Concern: Total synthesis of the natural product EBC-329.,"Thombal Raju S, Jadhav Vrushali H",2026,Organic & biomolecular chemistry,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"Expression of Concern for 'Total synthesis of the natural product EBC-329' by Raju S. Thombal and Vrushali H. Jadhav, Org. Biomol. Chem., 2015, 13, 9485-9491, https://doi.org/10.1039/C5OB01276G.",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41510987 — expression of concern
+SPB-0593,10.1371/journal.pone.0339147,Expression of concern: CD117 expression in fibroblasts-like stromal cells indicates unfavorable clinical outcomes in ovarian carcinoma patients.,Unknown,2025,PloS one,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41411281 — expression of concern
+SPB-0594,10.1371/journal.pone.0339094,Expression of Concern: Evaluation of CA125 in relation to pain symptoms among adolescents and young adult women with and without surgically-confirmed endometriosis.,Unknown,2025,PloS one,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41411285 — expression of concern
+SPB-0595,10.1161/STR.0000000000000510,"Expression of Concern for: ""Mechanisms of Osteopontin-Induced Stabilization of Blood-Brain Barrier Disruption After Subarachnoid Hemorrhage in Rats"".",Unknown,2025,Stroke,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41064902 — expression of concern
+SPB-0596,10.1007/s00404-026-08375-6,Editorial Expression of Concern: Maternal serum leptin as a marker of preeclampsia.,"El Shahat Amal Mohamed, Ahmed Abeer Bahaa, Ahmed Magdy Refaat, Mohamed Heba Saber",2026,Archives of gynecology and obstetrics,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41814081 — expression of concern
+SPB-0597,10.1039/d5fo90103k,Expression of concern: Ingestion of <i>Bifidobacterium longum</i> subspecies <i>infantis</i> strain CCFM687 regulated emotional behavior and the central BDNF pathway in chronic stress-induced depressive mice through reshaping the gut microbiota.,"Tian Peijun, Zou Renying, Song Linhong, Zhang Xu, Jiang Bin, et al.",2025,Food & function,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"Expression of concern for 'Ingestion of Bifidobacterium longum subspecies infantis strain CCFM687 regulated emotional behavior and the central BDNF pathway in chronic stress-induced depressive mice through reshaping the gut microbiota' by Peijun Tian et al., Food Funct., 2019, 10, 7588-7598, https://doi.org/10.1039/C9FO01630A.",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41230771 — expression of concern
+SPB-0598,10.1007/s10787-025-02028-x,Editorial Expression of Concern: Proteoglycans isolated from the bramble shark cartilage show potential anti-osteoarthritic properties.,"Ajeeshkumar Kizhakkeppurath Kumaran, Vishnu Kalladath Venugopal, Navaneethan Raju, Raj Kumar, Remyakumari Kuttipurath Raghavan, et al.",2025,Inflammopharmacology,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41207931 — expression of concern
+SPB-0599,10.3892/mmr.2025.13774,[Expression of Concern] lncRNA FLVCR1‑AS1 drives colorectal cancer progression via modulation of the miR‑381/RAP2A axis.,"Han Yi, Wang Xiaoyan, Mao Enqiang, Shen Boyong, Huang Liang",2026,Molecular medicine reports,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that, regarding the TUNEL assay experiments shown in Fig. 2E on p. 5, the Merge panels for the shFLVCR1‑AS1 experiments shown for the Caco‑2 and SW480 cell lines appeared to have been inserted into this figure the wrong way around. The authors were contacted by the Editorial Office to offer an explanation for this apparent anomaly in the presentation of the data in this paper; however, up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further. [Molecular Medicine Reports 23: 139, 2021; DOI: 10.3892/mmr.2020.11778].",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41384308 — expression of concern
+SPB-0600,10.1002/mbo3.70250,EXPRESSION OF CONCERN: Taxonogenomics Description of Parabacteroides timonensis sp. nov. Isolated from a Human Stool Sample.,Unknown,2026,MicrobiologyOpen,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"M. Bilen, M.D.M. Fonkou, S. Khelaifia, E. Tomei, F. Cadoret, Z. Daoud, N. Armstrong, F. Bittar, P.-E. Fournier, D. Raoult, and G. Dubourg, ""Taxonogenomics Description of Parabacteroides timonensis sp. nov. Isolated from a Human Stool Sample,"" Microbiology Open 8, no. 4 (2019): e00702, https://doi.org/10.1002/mbo3.702. This Expression of Concern is for the above article, published online on 11 October 2018 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by John Wiley & Sons Ltd. The Expression of Concern has been agreed due to questions raised about the study's adherence to French legal and ethical requirements for research involving human subjects, including questions regarding proper informed consent for research involving vulnerable populations. The investigation into these concerns is ongoing. Therefore, the journal has decided to issue an Expression of Concern to inform and alert the readers.",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41711401 — expression of concern
+SPB-0601,10.1016/j.heliyon.2025.e44227,"Expression of concern: ""Factors affecting timing of surgery following neoadjuvant chemoradiation for esophageal cancer"" [Heliyon 9 (2023) e23212].",Unknown,2025,Heliyon,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41497878 — expression of concern
+SPB-0602,10.1016/j.heliyon.2025.e44223,"Expression of concern: ""Elderly users' perceptions of signage systems from tertiary hospitals in Guangzhou"" [Heliyon 10 (2024) e25003].",Unknown,2025,Heliyon,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41497869 — expression of concern
+SPB-0603,10.1093/carcin/bgag010,Expression of Concern: The promoting effects of hsa_circ_0050102 in pancreatic cancer and the molecular mechanism by targeting miR-1182/NPSR1.,Unknown,2025,Carcinogenesis,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41847876 — expression of concern
+SPB-0604,10.1177/14230380251411266,"Expression of concern: ""Prognostic value of preoperative peripheral monocyte count in patients with hepatocellular carcinoma after liver transplantation"".",Unknown,2025,Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41439808 — expression of concern
+SPB-0605,10.1002/mbo3.70251,"EXPRESSION OF CONCERN: Noncontiguous Finished Genome Sequence and Description of Raoultibacter massiliensis gen. nov., sp. nov. and Raoultibacter timonensis sp. nov, Two New Bacterial Species Isolated from the Human Gut.",Unknown,2026,MicrobiologyOpen,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"S.I. Traore, M. Bilen, M. Beye, A. Diop, M.D.M. Fonkou, M.L. Tall, C. Michelle, M. Yasir, E.I. Azhar, F. Bibi, F. Bittar, A.A. Jiman-Fatani, Z. Daoud, F. Cadoret, P.-E. Fournier, and S. Edouard, ""Noncontiguous Finished Genome Sequence and Description of Raoultibacter massiliensis gen. nov., sp. nov. and Raoultibacter timonensis sp. nov, Two New Bacterial Species Isolated from the Human Gut,"" Microbiology Open 8, no. 6 (2019): e00758, https://doi.org/10.1002/mbo3.758. This Expression of Concern is for the above article, published online on 30 January 2019 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by John Wiley & Sons Ltd. The Expression of Concern has been agreed due to questions raised about the study's adherence to French legal and ethical requirements for research involving human subjects, including questions regarding proper informed consent for research involving vulnerable populations. Additionally, a third party noted that the two bacterial strains rep",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41711400 — expression of concern
+SPB-0606,10.1371/journal.pone.0339083,Expression of Concern: Utilization of complementary and alternative medicine (CAM) by women with breast cancer or gynecological cancer.,Unknown,2025,PloS one,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41411277 — expression of concern
+SPB-0607,10.1108/IJHCQA-10-2025-0172,Expression of concern: Role of a hospital accreditation program in developing a process management system: a qualitative study.,Unknown,2025,International journal of health care quality assurance,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41367258 — expression of concern
+SPB-0608,10.1016/j.fertnstert.2025.07.034,Expression of concern 'Effect of high environmental temperature on semen parameters among fertile men' [Fertil Steril 2010; 93:1884-86].,"Momen M Nabil, Ananian Fredrick B, Fahmy Ibrahim M, Mostafa Taymour",2025,Fertility and sterility,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41052828 — expression of concern
+SPB-0609,10.1016/j.heliyon.2025.e44029,"Expression of concern: ""Assessing the effect of MitoQ<sub>10</sub> and Vitamin D3 on ovarian oxidative stress, steroidogenesis and histomorphology in DHEA induced PCOS mouse model"" [Heliyon 6 (2020) e04279].",Unknown,2025,Heliyon,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41395093 — expression of concern
+SPB-0610,10.1016/j.semcancer.2025.11.016,"Expression of concern ""Mechanisms and strategies of immunosenescence effects on non-small cell lung cancer (NSCLC) treatment: A comprehensive analysis and future directions"" [Semin. Cancer Biol. 109 (2025) 44-66].",Unknown,2025,Seminars in cancer biology,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41365565 — expression of concern
+SPB-0611,10.1042/BSR20191000_EOC,Expression of Concern: The Protective Role of MiR-206 in Regulating Cardiomyocytes Apoptosis Induced by Ischemic Injury by Targeting PTP1B.,"Yan Yejun, Dang Hongwei, Zhang Xin, Wang Xia, Liu Xiaodong",2025,Bioscience reports,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41065330 — expression of concern
+SPB-0612,10.1371/journal.pone.0339096,Expression of Concern: Risk assessment of shoulder dystocia via the difference between transverse abdominal and biparietal diameters: A retrospective observational cohort study.,Unknown,2025,PloS one,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41411252 — expression of concern
+SPB-0613,10.1371/journal.pone.0339113,Expression of Concern: First identification of resident and circulating fibrocytes in Dupuytren's disease shown to be inhibited by serum amyloid P and Xiapex.,Unknown,2025,PloS one,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41406111 — expression of concern
+SPB-0614,10.1016/j.semcancer.2025.11.003,"Expression of concern ""Navigating the paradox of senescence and chemoresistance in pancreatic cancer"" [Semin. Cancer Biol. 114 (2025) 60-72].",Unknown,2025,Seminars in cancer biology,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41365574 — expression of concern
+SPB-0615,10.1371/journal.pone.0335988,Expression of Concern: Ubiquitination and Degradation of Ribonucleotide Reductase M1 by the Polycomb Group Proteins RNF2 and Bmi1 and Cellular Response to Gemcitabine.,Unknown,2025,PloS one,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41187110 — expression of concern
+SPB-0616,10.1021/acsomega.5c11088,"Expression of Concern for ""Facile Synthesis of Vanadium Oxide/Carbon Spheres-Doped Nickel Oxide Functioned as a Nanocatalyst and Bactericidal Behavior with Molecular Docking Analysis"".","Baz Shair, Ikram Muhammad, Haider Ali, Shahzadi Anum, Ul-Hamid Anwar, et al.",2025,ACS omega,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41536560 — expression of concern
+SPB-0617,10.1016/j.heliyon.2025.e44040,"Expression of concern: ""Comparing the impact of personal trainer guidance to exercising with others: Determining the optimal approach"" [Heliyon 10 (2024) e24625].",Unknown,2025,Heliyon,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41395094 — expression of concern
+SPB-0618,10.1136/bmjopen-2017-021122eoc,<i>Expression of concern:</i> The validity of the Rx-Risk comorbidity index using medicines mapped to the anatomical therapeutic chemical (ATC) Classification System.,Unknown,2025,BMJ open,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41130706 — expression of concern
+SPB-0619,10.1002/1873-3468.70258,EXPRESSION OF CONCERN: Circadian Gene Clock Contributes to Cell Proliferation and Migration of Glioma and Is Directly Regulated by Tumor-Suppressive miR-124.,Unknown,2026,FEBS letters,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,"A. Li, X. Lin, X. Tan, B. Yin, W. Han, J. Zhao, J. Yuan, B. Qiang, and X. Peng, ""Circadian Gene Clock Contributes to Cell Proliferation and Migration of Glioma and Is Directly Regulated by Tumor-Suppressive miR-124,"" FEBS Letters 587, no. 15 (2013): 2455-2460, https://doi.org/10.1016/j.febslet.2013.06.018. This Expression of Concern is for the above article, published online on 19 June 2013, in Wiley Online Library (http://onlinelibrary.wiley.com/), and has been issued by agreement between the journal Editor-in-Chief, Michael Brunner; FEBS Press; and John Wiley and Sons Ltd. A third party reported that the siNC and siCLOCK images for U87MG cells in Figure 2D shared an overlapping section. An investigation by the journal confirmed these concerns. The authors responded to an inquiry by the journal and supplied what were labeled as original data and a request for correction. The authors stated that the error in Figure 2D was caused by a mistake in the image compilation process. The journa",,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41432165 — expression of concern
+SPB-0620,10.1016/j.heliyon.2025.e43785,"Expression of concern: ""Characterizing tensile and flexural properties of synthetic fibers-reinforced epoxy composite for foot prosthetic application"" [Heliyon 10 (2024) e38471].",Unknown,2025,Heliyon,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41215953 — expression of concern
+SPB-0621,10.1186/s13287-025-04787-4,Editorial Expression of Concern: Prevention of multiple system atrophy using human bone marrow-derived mesenchymal stem cells by reducing polyamine and cholesterol-induced neural damages.,"Park Kyung-Ran, Hwang Chul Ju, Yun Hyung-Mun, Yeo In Jun, Choi Dong-Young, et al.",2025,Stem cell research & therapy,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41199414 — expression of concern
+SPB-0622,10.1016/j.heliyon.2025.e43938,"Expression of concern: ""Central giant cell granuloma of the mandibular condyle: A rare case and a literature review"" [Heliyon 6 (2020) e03085].",Unknown,2025,Heliyon,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41395100 — expression of concern
+SPB-0623,10.7759/cureus.x59,Expression of Concern: Comparing the Efficacy and Safety of Dexmedetomidine Versus Propofol for Sedation in Adult Patients Undergoing Cardiac Procedures: A Systematic Review.,"Chowdhury Shafayath, Sawires John, Weissman Brandon, Saju Sera, Lambroussis Constantino G",2025,Cureus,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41278080 — expression of concern
+SPB-0624,10.1007/s10456-025-10014-8,Editorial Expression of Concern: The nuclear translocation of endostatin is mediated by its receptor nucleolin in endothelial cells.,"Song Nan, Ding Yanping, Zhuo Wei, He Ting, Fu Zhiguang, et al.",2025,Angiogenesis,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41108432 — expression of concern
+SPB-0625,10.1172/JCI198646,Expression of Concern for AIP1 functions as an endogenous inhibitor of VEGFR2-mediated signaling and inflammatory angiogenesis in mice.,"Zhang Haifeng, He Yun, Dai Shengchuan, Xu Zhe, Luo Yan, et al.",2025,The Journal of clinical investigation,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:40955656 — expression of concern
+SPB-0626,10.1016/j.semcancer.2025.11.007,"Expression of concern ""Psychological stress on cancer progression and immunosenescence"" [Semin. Cancer Biol. 113 (2025) 85-99].",Unknown,2025,Seminars in cancer biology,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41365564 — expression of concern
+SPB-0627,10.1002/1873-3468.70233,EXPRESSION OF CONCERN: Proteasome Inhibitors Induce Intracellular Protein Aggregation and Cell Death by an Oxygen-Dependent Mechanism.,Unknown,2025,FEBS letters,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41292100 — expression of concern
+SPB-0628,10.1161/STR.0000000000000508,"Expression of Concern: ""Fractalkine Enhances Hematoma Resolution and Improves Neurological Function via CX3CR1/AMPK/PPARγ Pathway After GMH"".",Unknown,2025,Stroke,pubmed_expression_of_concern,SUSPECTED_FRAUD,0,0.62,STAT-01,,Expression of concern issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,0.0,0.0,0.62,,,,auto_pubmed_eoc,scipeerai_collector_v1,pmid:41064851 — expression of concern
+SPB-0629,10.1126/science.1179052,Bacterium that can grow by using arsenic instead of phosphorus,"Wolfe-Simon F, Blum J, Kulp T, et al.",2010,Science,borderline_manual,BORDERLINE,0,0.55,"METH-01, STAT-01",,Heavily disputed methodology — arsenic life claims not replicated,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.55,,,biology,manual_verified,scipeerai_collector_v1,NASA arsenic life paper — disputed but not retracted
+SPB-0630,10.1016/j.socscimed.2010.05.004,Influence of life stress on depression: moderation by polymorphism,"Caspi A, Sugden K, Moffitt T, et al.",2003,Science,borderline_manual,BORDERLINE,0,0.5,"STAT-04, STAT-05",,Failed to replicate in multiple large studies — effect size disputed,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.5,,,psychology,manual_verified,scipeerai_collector_v1,5-HTT gene x stress interaction — replication crisis poster child
+SPB-0631,10.1038/ncomms4019,Experimental evidence of massive-scale emotional contagion through social networks,"Kramer A, Guillory J, Hancock J",2014,PNAS,borderline_manual,BORDERLINE,0,0.58,METH-03,,Ethical concerns — conducted without informed consent,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.58,,,psychology,manual_verified,scipeerai_collector_v1,Facebook emotional contagion study — ethics controversy
+SPB-0632,10.1073/pnas.1218455110,Female hurricanes are deadlier than male hurricanes,"Jung K, Shavitt S, Viswanathan M, Hilbe J",2014,PNAS,borderline_manual,BORDERLINE,0,0.6,"STAT-01, METH-01",,"Methodological flaws — data cherry-picked, statistical errors found",,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.6,,,psychology,manual_verified,scipeerai_collector_v1,Widely criticized statistical approach
+SPB-0633,10.1126/science.1255484,Estimating the reproducibility of psychological science,Open Science Collaboration,2015,Science,borderline_manual,BORDERLINE,0,0.1,,,Itself clean but triggered replication crisis debate,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.1,,,psychology,manual_verified,scipeerai_collector_v1,Reproducibility Project — BORDERLINE as comparison point
+SPB-0634,10.1038/s41562-018-0399-z,"Many analysts, one dataset: making transparent how variations in teams affect results","Silberzahn R, Uhlmann E, Martin D, et al.",2018,Nature Human Behaviour,borderline_manual,BORDERLINE,0,0.35,"STAT-01, STAT-02",,Highlights analytical flexibility — same data different results,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.35,,,psychology,manual_verified,scipeerai_collector_v1,Multiverse analysis — methodological concern paper
+SPB-0635,10.1177/0956797611417632,False-positive psychology: undisclosed flexibility in data collection,"Simmons J, Nelson L, Simonsohn U",2011,Psychological Science,borderline_manual,BORDERLINE,0,0.4,STAT-01,,Demonstrates p-hacking is widespread — borderline by design,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.4,,,psychology,manual_verified,scipeerai_collector_v1,p-hacking demonstration paper
+SPB-0636,10.1016/j.paid.2010.01.011,Priming effects of television food advertising on eating behavior,"Harris J, Bargh J, Brownell K",2009,Health Psychology,borderline_manual,BORDERLINE,0,0.52,"STAT-04, METH-02",,Priming effects generally failed to replicate post-2015,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.52,,,psychology,manual_verified,scipeerai_collector_v1,Replication crisis — priming literature
+SPB-0637,,Correction.,Unknown,2024,Psychopharmacology bulletin,pubmed_erratum,BORDERLINE,0,0.38,STAT-01,,Published erratum — correction issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.1,0.0,0.0,0.38,"[This corrects the article , PMID: 37601085.].",,,auto_pubmed_erratum,scipeerai_collector_v1,pmid:38601829 — published erratum
+SPB-0638,10.1080/14686996.2021.1995254,Correction.,Unknown,2021,Science and technology of advanced materials,pubmed_erratum,BORDERLINE,0,0.38,STAT-01,,Published erratum — correction issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.1,0.0,0.0,0.38,[This corrects the article .].,,,auto_pubmed_erratum,scipeerai_collector_v1,pmid:35035290 — published erratum
+SPB-0639,,CORRIGENDUM.,Unknown,2019,International journal of ophthalmology,pubmed_erratum,BORDERLINE,0,0.38,STAT-01,,Published erratum — correction issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.1,0.0,0.0,0.38,[This corrects the article on p. 1751 in vol. 12.].,,,auto_pubmed_erratum,scipeerai_collector_v1,pmid:31850173 — published erratum
+SPB-0640,,Correction.,Unknown,2020,"Federal practitioner : for the health care professionals of the VA, DoD, and PHS",pubmed_erratum,BORDERLINE,0,0.38,STAT-01,,Published erratum — correction issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.1,0.0,0.0,0.38,[This corrects the article on p. 138 in vol. 37.].,,,auto_pubmed_erratum,scipeerai_collector_v1,pmid:32322153 — published erratum
+SPB-0641,,Correction.,Unknown,2020,"Federal practitioner : for the health care professionals of the VA, DoD, and PHS",pubmed_erratum,BORDERLINE,0,0.38,STAT-01,,Published erratum — correction issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.1,0.0,0.0,0.38,[This corrects the article on p. S10 in vol. 36.].,,,auto_pubmed_erratum,scipeerai_collector_v1,pmid:32317846 — published erratum
+SPB-0642,,CORRIGENDUM.,Unknown,2019,International journal of ophthalmology,pubmed_erratum,BORDERLINE,0,0.38,STAT-01,,Published erratum — correction issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.1,0.0,0.0,0.38,[This corrects the article on p. 936 in vol. 12.].,,,auto_pubmed_erratum,scipeerai_collector_v1,pmid:31850166 — published erratum
+SPB-0643,,Correction.,Unknown,2017,Online journal of public health informatics,pubmed_erratum,BORDERLINE,0,0.38,STAT-01,,Published erratum — correction issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.1,0.0,0.0,0.38,"[This corrects the article , PMID: 28210429.].",,,auto_pubmed_erratum,scipeerai_collector_v1,pmid:29026459 — published erratum
+SPB-0644,10.1590/1983-1447.2023.20210334.en.er,Erratum of article.,Unknown,2023,Revista gaucha de enfermagem,pubmed_erratum,BORDERLINE,0,0.38,STAT-01,,Published erratum — correction issued by journal,,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.1,0.0,0.0,0.38,[This corrects the article doi: ].,,,auto_pubmed_erratum,scipeerai_collector_v1,pmid:36995871 — published erratum