Daily Papers

Clinical diagnostic workups typically follow a modality escalation pathway: after initial clinical evaluation, clinicians begin with routine structural imaging (e.g., MRI), selectively add sequences such as FLAIR or T2 to refine the differential, and reserve molecular imaging (e.g., amyloid-PET) for cases that remain uncertain after standard evaluation. Consequently, patients are observed with heterogeneous and often incomplete modality subsets. However, most current AI models assume fixed data modalities as the model inputs. In this paper, we present BrainAnytime, a unified pretraining framework pretrained on 34,899 3D brain scans from five datasets that support brain image analysis under arbitrary modality availability spanning multi-sequence MRI and amyloid-PET. A single model accepts whatever imaging is available, from a lone T1 scan to a full multimodal workup. Pretraining learns structural-molecular correspondences between MRI and PET via cross-modal distillation (RCMD) and prioritizes disease-vulnerable anatomy via atlas-guided curriculum masking (PACM), all within a shared 3D masked autoencoder (Multi-MAE3D). Across four downstream tasks and five clinically motivated modality settings, BrainAnytime largely outperforms modality-specific models, missing-modality baselines, and large-scale brain MRI pretrained foundation models on most modality settings. Notably, it surpasses the strongest missing-modality baselines with relative improvements of 6.2% and 7.0% in average accuracy on CN vs. AD and CN vs. MCI classification, respectively. Code is available at https://github.com/SDH-Lab/BrainAnytime.

We introduce SPECTRE, a fully transformer-based foundation model for volumetric computed tomography (CT). Our Self-Supervised & Cross-Modal Pretraining for CT Representation Extraction (SPECTRE) approach utilizes scalable 3D Vision Transformer architectures and modern self-supervised and vision-language pretraining strategies to learn general-purpose CT representations. Volumetric CT poses unique challenges, such as extreme token scaling, geometric anisotropy, and weak or noisy clinical supervision, that make standard transformer and contrastive learning recipes ineffective out of the box. The framework jointly optimizes a local transformer for high-resolution volumetric feature extraction and a global transformer for whole-scan context modeling, making large-scale 3D attention computationally tractable. Notably, SPECTRE is trained exclusively on openly available CT datasets, demonstrating that high-performing, generalizable representations can be achieved without relying on private data. Pretraining combines DINO-style self-distillation with SigLIP-based vision-language alignment using paired radiology reports, yielding features that are both geometrically consistent and clinically meaningful. Across multiple CT benchmarks, SPECTRE consistently outperforms prior CT foundation models in both zero-shot and fine-tuned settings, establishing SPECTRE as a scalable, open, and fully transformer-based foundation model for 3D medical imaging.

We explore the potential of large-scale noisily labeled data to enhance feature learning by pretraining semantic segmentation models within a multi-modal framework for geospatial applications. We propose a novel Cross-modal Sample Selection (CromSS) method, a weakly supervised pretraining strategy designed to improve feature representations through cross-modal consistency and noise mitigation techniques. Unlike conventional pretraining approaches, CromSS exploits massive amounts of noisy and easy-to-come-by labels for improved feature learning beneficial to semantic segmentation tasks. We investigate middle and late fusion strategies to optimize the multi-modal pretraining architecture design. We also introduce a cross-modal sample selection module to mitigate the adverse effects of label noise, which employs a cross-modal entangling strategy to refine the estimated confidence masks within each modality to guide the sampling process. Additionally, we introduce a spatial-temporal label smoothing technique to counteract overconfidence for enhanced robustness against noisy labels. To validate our approach, we assembled the multi-modal dataset, NoLDO-S12, which consists of a large-scale noisy label subset from Google's Dynamic World (DW) dataset for pretraining and two downstream subsets with high-quality labels from Google DW and OpenStreetMap (OSM) for transfer learning. Experimental results on two downstream tasks and the publicly available DFC2020 dataset demonstrate that when effectively utilized, the low-cost noisy labels can significantly enhance feature learning for segmentation tasks. All data, code, and pretrained weights will be made publicly available.

Human Activity Recognition (HAR) based on wearable inertial sensors plays a critical role in remote health monitoring. In patients with movement disorders, the ability to detect abnormal patient movements in their home environments can enable continuous optimization of treatments and help alert caretakers as needed. Machine learning approaches have been proposed for HAR tasks using Inertial Measurement Unit (IMU) data; however, most rely on application-specific labels and lack generalizability to data collected in different environments or populations. To address this limitation, we propose a new cross-modal self-supervised pretraining approach to learn representations from large-sale unlabeled IMU-video data and demonstrate improved generalizability in HAR tasks on out of distribution (OOD) IMU datasets, including a dataset collected from patients with Parkinson's disease. Specifically, our results indicate that the proposed cross-modal pretraining approach outperforms the current state-of-the-art IMU-video pretraining approach and IMU-only pretraining under zero-shot and few-shot evaluations. Broadly, our study provides evidence that in highly dynamic data modalities, such as IMU signals, cross-modal pretraining may be a useful tool to learn generalizable data representations. Our software is available at https://github.com/scheshmi/IMU-Video-OOD-HAR.

In this work, we construct the largest dataset for multimodal pretraining in Chinese, which consists of over 1.9TB images and 292GB texts that cover a wide range of domains. We propose a cross-modal pretraining method called M6, referring to Multi-Modality to Multi-Modality Multitask Mega-transformer, for unified pretraining on the data of single modality and multiple modalities. We scale the model size up to 10 billion and 100 billion parameters, and build the largest pretrained model in Chinese. We apply the model to a series of downstream applications, and demonstrate its outstanding performance in comparison with strong baselines. Furthermore, we specifically design a downstream task of text-guided image generation, and show that the finetuned M6 can create high-quality images with high resolution and abundant details.

We present Uni-MoE 2.0 from the Lychee family. As a fully open-source omnimodal large model (OLM), it substantially advances Lychee's Uni-MoE series in language-centric multimodal understanding, reasoning, and generating. Based on the Qwen2.5-7B dense architecture, we build Uni-MoE-2.0-Omni from scratch through three core contributions: dynamic-capacity Mixture-of-Experts (MoE) design, a progressive training strategy enhanced with an iterative reinforcement strategy, and a carefully curated multimodal data matching technique. It is capable of omnimodal understanding, as well as generating images, text, and speech. Architecturally, our new MoE framework balances computational efficiency and capability for 10 cross-modal inputs using shared, routed, and null experts, while our Omni-Modality 3D RoPE ensures spatio-temporal cross-modality alignment in the self-attention layer. For training, following cross-modal pretraining, we use a progressive supervised fine-tuning strategy that activates modality-specific experts and is enhanced by balanced data composition and an iterative GSPO-DPO method to stabilise RL training and improve reasoning. Data-wise, the base model, trained on approximately 75B tokens of open-source multimodal data, is equipped with special speech and image generation tokens, allowing it to learn these generative tasks by conditioning its outputs on linguistic cues. Extensive evaluation across 85 benchmarks demonstrates that our model achieves SOTA or highly competitive performance against leading OLMs, surpassing Qwen2.5-Omni (trained with 1.2T tokens) on over 50 of 76 benchmarks. Key strengths include video understanding (+7% avg. of 8), omnimodallity understanding (+7% avg. of 4), and audiovisual reasoning (+4%). It also advances long-form speech processing (reducing WER by 4.2%) and leads in low-level image processing and controllable generation across 5 metrics.

Multimodal large language models (MLLMs) have rapidly advanced, yet their adoption in medicine remains limited by gaps in domain coverage, modality alignment, and grounded reasoning. In this work, we introduce MedMO, a medical foundation model built upon a generalized MLLM architecture and trained exclusively on large-scale, domain-specific data. MedMO follows a multi-stage training recipe: (i) cross-modal pretraining to align heterogeneous visual encoders with a medical language backbone; (ii) instruction tuning on multi-task supervision that spans captioning, VQA, report generation, retrieval, and grounded disease localization with bounding boxes; and (iii) reinforcement learning with verifiable rewards that combine factuality checks with a box-level GIoU reward to strengthen spatial grounding and step-by-step reasoning in complex clinical scenarios. MedMO consistently outperforms strong open-source medical MLLMs across multiple modalities and tasks. On VQA benchmarks, MedMO achieves an average accuracy improvement of +13.7% over the baseline and performs within 1.9% of the SOTA Fleming-VL. For text-based QA, it attains +6.9% over the baseline and +14.5% over Fleming-VL. In medical report generation, MedMO delivers significant gains in both semantic and clinical accuracy. Moreover, it exhibits strong grounding capability, achieving an IoU improvement of +40.4 over the baseline and +37.0% over Fleming-VL, underscoring its robust spatial reasoning and localization performance. Evaluations across radiology, ophthalmology, and pathology-microscopy confirm MedMO's broad cross-modality generalization. We release two versions of MedMO: 4B and 8B. Project is available at https://genmilab.github.io/MedMO-Page

LiDAR representation learning has emerged as a promising approach to reducing reliance on costly and labor-intensive human annotations. While existing methods primarily focus on spatial alignment between LiDAR and camera sensors, they often overlook the temporal dynamics critical for capturing motion and scene continuity in driving scenarios. To address this limitation, we propose SuperFlow++, a novel framework that integrates spatiotemporal cues in both pretraining and downstream tasks using consecutive LiDAR-camera pairs. SuperFlow++ introduces four key components: (1) a view consistency alignment module to unify semantic information across camera views, (2) a dense-to-sparse consistency regularization mechanism to enhance feature robustness across varying point cloud densities, (3) a flow-based contrastive learning approach that models temporal relationships for improved scene understanding, and (4) a temporal voting strategy that propagates semantic information across LiDAR scans to improve prediction consistency. Extensive evaluations on 11 heterogeneous LiDAR datasets demonstrate that SuperFlow++ outperforms state-of-the-art methods across diverse tasks and driving conditions. Furthermore, by scaling both 2D and 3D backbones during pretraining, we uncover emergent properties that provide deeper insights into developing scalable 3D foundation models. With strong generalizability and computational efficiency, SuperFlow++ establishes a new benchmark for data-efficient LiDAR-based perception in autonomous driving. The code is publicly available at https://github.com/Xiangxu-0103/SuperFlow

Spatial transcriptomics enables simultaneous measurement of gene expression and tissue morphology, offering unprecedented insights into cellular organization and disease mechanisms. However, the field lacks comprehensive benchmarks for evaluating multimodal learning methods that leverage both histology images and gene expression data. Here, we present HESCAPE, a large-scale benchmark for cross-modal contrastive pretraining in spatial transcriptomics, built on a curated pan-organ dataset spanning 6 different gene panels and 54 donors. We systematically evaluated state-of-the-art image and gene expression encoders across multiple pretraining strategies and assessed their effectiveness on two downstream tasks: gene mutation classification and gene expression prediction. Our benchmark demonstrates that gene expression encoders are the primary determinant of strong representational alignment, and that gene models pretrained on spatial transcriptomics data outperform both those trained without spatial data and simple baseline approaches. However, downstream task evaluation reveals a striking contradiction: while contrastive pretraining consistently improves gene mutation classification performance, it degrades direct gene expression prediction compared to baseline encoders trained without cross-modal objectives. We identify batch effects as a key factor that interferes with effective cross-modal alignment. Our findings highlight the critical need for batch-robust multimodal learning approaches in spatial transcriptomics. To accelerate progress in this direction, we release HESCAPE, providing standardized datasets, evaluation protocols, and benchmarking tools for the community

Visual emotion analysis holds significant research value in both computer vision and psychology. However, existing methods for visual emotion analysis suffer from limited generalizability due to the ambiguity of emotion perception and the diversity of data scenarios. To tackle this issue, we introduce UniEmoX, a cross-modal semantic-guided large-scale pretraining framework. Inspired by psychological research emphasizing the inseparability of the emotional exploration process from the interaction between individuals and their environment, UniEmoX integrates scene-centric and person-centric low-level image spatial structural information, aiming to derive more nuanced and discriminative emotional representations. By exploiting the similarity between paired and unpaired image-text samples, UniEmoX distills rich semantic knowledge from the CLIP model to enhance emotional embedding representations more effectively. To the best of our knowledge, this is the first large-scale pretraining framework that integrates psychological theories with contemporary contrastive learning and masked image modeling techniques for emotion analysis across diverse scenarios. Additionally, we develop a visual emotional dataset titled Emo8. Emo8 samples cover a range of domains, including cartoon, natural, realistic, science fiction and advertising cover styles, covering nearly all common emotional scenes. Comprehensive experiments conducted on six benchmark datasets across two downstream tasks validate the effectiveness of UniEmoX. The source code is available at https://github.com/chincharles/u-emo.

Multimodal Large Language Models (MLLMs) may memorize sensitive cross-modal information during pretraining. However, existing MLLM unlearning benchmarks rely on synthetic knowledge injection or complete subject-level deletion, which fail to capture realistic, personalized deletion requests that require fine-grained factual control. In this paper, we introduce PPU-Bench, a real-world and fine-tuning-free benchmark for personalized partial unlearning in MLLMs. PPU-Bench contains 24K multimodal and unimodal samples derived from pre-existing knowledge of 500 public figures under three progressively challenging settings: Complete, Selective, and Personalized unlearning. The benchmark evaluates whether methods can remove target knowledge while preserving non-target facts, model utility, and cross-modal consistency. Extensive experiments show that Complete Unlearning often suppresses visual identity rather than factual knowledge, while Selective and Personalized Unlearning expose significant forget--retain trade-offs and challenges in intra-subject factual boundaries. Robustness analysis under cross-image and prompt-based attacks reveals distinct vulnerabilities across different unlearning settings. Motivated by these findings, we propose Boundary-Aware Optimization (BAO), which explicitly models intra-subject forget-retain boundaries. Experimental results on two representative methods demonstrate that BAO can effectively enforce intra-subject factual boundaries.

Recent advances in Large Language Models (LLMs) have catalyzed the development of Large Multimodal Models (LMMs). However, existing research primarily focuses on tuning language and image instructions, ignoring the critical pretraining phase where models learn to process textual and visual modalities jointly. In this paper, we propose a new pretraining paradigm for LMMs to enhance the visual comprehension capabilities of LLMs by introducing a novel cross-modal comprehension stage. Specifically, we design a dynamically learnable prompt token pool and employ the Hungarian algorithm to replace part of the original visual tokens with the most relevant prompt tokens. Then, we conceptualize visual tokens as analogous to a "foreign language" for the LLMs and propose a mixed attention mechanism with bidirectional visual attention and unidirectional textual attention to comprehensively enhance the understanding of visual tokens. Meanwhile, we integrate a detailed caption generation task, leveraging rich descriptions to further facilitate LLMs in understanding visual semantic information. After pretraining on 1.5 million publicly accessible data, we present a new foundation model called Croc. Experimental results demonstrate that Croc achieves new state-of-the-art performance on massive vision-language benchmarks. To support reproducibility and facilitate further research, we release the training code and pre-trained model weights at https://github.com/deepglint/Croc.

Vision-and-language pretraining (VLP) in the medical field utilizes contrastive learning on image-text pairs to achieve effective transfer across tasks. Yet, current VLP approaches with the masked modeling strategy face two challenges when applied to the medical domain. First, current models struggle to accurately reconstruct key pathological features due to the scarcity of medical data. Second, most methods only adopt either paired image-text or image-only data, failing to exploit the combination of both paired and unpaired data. To this end, this paper proposes the MMCLIP (Masked Medical Contrastive Language-Image Pre-Training) framework to enhance pathological learning and feature learning via unpaired data. First, we introduce the attention-masked image modeling (AttMIM) and entity-driven masked language modeling module (EntMLM), which learns to reconstruct pathological visual and textual tokens via multi-modal feature interaction, thus improving medical-enhanced features. The AttMIM module masks a portion of the image features that are highly responsive to textual features. This allows MMCLIP to improve the reconstruction of highly similar image data in medicine efficiency. Second, our MMCLIP capitalizes unpaired data to enhance multimodal learning by introducing disease-kind prompts. The experimental results show that MMCLIP achieves SOTA for zero-shot and fine-tuning classification performance on five datasets. Our code will be available at https://github.com/AIGeeksGroup/MMCLIP.

Biosignals acquired from different locations on the body often provide temporally ordered views of the same underlying physiological process. However, most existing self supervised learning methods treat these signals as interchangeable views, overlooking the directional temporal dynamics that link them. A canonical example is the relationship between electrocardiography (ECG), which captures the electrical activation initiating each heartbeat, and photoplethysmography (PPG), which records the resulting peripheral pulse delayed by vascular dynamics. To capture this structured relationship, we introduce xMAE, a biosignal pretraining framework that leverages masked cross modal reconstruction across temporally ordered biosignals as a training time constraint to encourage physiologically meaningful timing structure in the learned representations. We show that pretraining with xMAE yields representations that outperform both unimodal and multimodal baselines on 15 of 19 downstream tasks, including cardiovascular outcome prediction, abnormal laboratory test detection, sleep staging, and demographic inference, while generalizing across devices, body locations, and acquisition settings. Further analysis suggests that the ECG PPG timing structure is reflected in the learned PPG representations. More broadly, xMAE demonstrates the effectiveness of incorporating temporal structure into multimodal pretraining when signals observe different stages of a shared underlying process. Code is available at https://github.com/hzhou3/xMAE.

Recent advancements in vision foundation models (VFMs) have revolutionized visual perception in 2D, yet their potential for 3D scene understanding, particularly in autonomous driving applications, remains underexplored. In this paper, we introduce LargeAD, a versatile and scalable framework designed for large-scale 3D pretraining across diverse real-world driving datasets. Our framework leverages VFMs to extract semantically rich superpixels from 2D images, which are aligned with LiDAR point clouds to generate high-quality contrastive samples. This alignment facilitates cross-modal representation learning, enhancing the semantic consistency between 2D and 3D data. We introduce several key innovations: i) VFM-driven superpixel generation for detailed semantic representation, ii) a VFM-assisted contrastive learning strategy to align multimodal features, iii) superpoint temporal consistency to maintain stable representations across time, and iv) multi-source data pretraining to generalize across various LiDAR configurations. Our approach delivers significant performance improvements over state-of-the-art methods in both linear probing and fine-tuning tasks for both LiDAR-based segmentation and object detection. Extensive experiments on eleven large-scale multi-modal datasets highlight our superior performance, demonstrating the adaptability, efficiency, and robustness in real-world autonomous driving scenarios.

Modern retrieval systems often struggle with upgrading to new and more powerful models due to the incompatibility of embeddings between the old and new models. This necessitates a costly process known as backfilling, which involves re-computing the embeddings for a large number of data samples. In vision, Backward-compatible Training (BT) has been proposed to ensure that the new model aligns with the old model's embeddings. This paper extends the concept of vision-only BT to the field of cross-modal retrieval, marking the first attempt to address Cross-modal BT (XBT). Our goal is to achieve backward-compatibility between Vision-Language Pretraining (VLP) models, such as CLIP, for the cross-modal retrieval task. To address XBT challenges, we propose an efficient solution: a projection module that maps the new model's embeddings to those of the old model. This module, pretrained solely with text data, significantly reduces the number of image-text pairs required for XBT learning, and, once it is pretrained, it avoids using the old model during training. Furthermore, we utilize parameter-efficient training strategies that improve efficiency and preserve the off-the-shelf new model's knowledge by avoiding any modifications. Experimental results on cross-modal retrieval datasets demonstrate the effectiveness of XBT and its potential to enable backfill-free upgrades when a new VLP model emerges.

Image-text retrieval, as a fundamental and important branch of information retrieval, has attracted extensive research attentions. The main challenge of this task is cross-modal semantic understanding and matching. Some recent works focus more on fine-grained cross-modal semantic matching. With the prevalence of large scale multimodal pretraining models, several state-of-the-art models (e.g. X-VLM) have achieved near-perfect performance on widely-used image-text retrieval benchmarks, i.e. MSCOCO-Test-5K and Flickr30K-Test-1K. In this paper, we review the two common benchmarks and observe that they are insufficient to assess the true capability of models on fine-grained cross-modal semantic matching. The reason is that a large amount of images and texts in the benchmarks are coarse-grained. Based on the observation, we renovate the coarse-grained images and texts in the old benchmarks and establish the improved benchmarks called MSCOCO-FG and Flickr30K-FG. Specifically, on the image side, we enlarge the original image pool by adopting more similar images. On the text side, we propose a novel semi-automatic renovation approach to refine coarse-grained sentences into finer-grained ones with little human effort. Furthermore, we evaluate representative image-text retrieval models on our new benchmarks to demonstrate the effectiveness of our method. We also analyze the capability of models on fine-grained semantic comprehension through extensive experiments. The results show that even the state-of-the-art models have much room for improvement in fine-grained semantic understanding, especially in distinguishing attributes of close objects in images. Our code and improved benchmark datasets are publicly available at: https://github.com/cwj1412/MSCOCO-Flikcr30K_FG, which we hope will inspire further in-depth research on cross-modal retrieval.

As deep learning models evolve, new applications and challenges are rapidly emerging. Tasks that once relied on a single modality, such as text, images, or audio, are now enriched by seamless interactions between multimodal data. These connections bridge information gaps: an image can visually materialize a text, while audio can add context to an image. Researchers have developed numerous multimodal models, but most rely on resource-intensive training across multiple modalities. Similarly, extending these models to new languages often follows the same resource-heavy training strategy. In this work, we propose a multimodal and multilingual architecture, CACARA, trained through emergent alignment learning, enabling the seamless integration of new modalities into an existing bimodal/multimodal model without requiring full retraining. This work breaks new ground by demonstrating that this emergent alignment paradigm can unlock multilingual capabilities from monolingual training. By fine-tuning the newly incorporated modality only on data aligned with the English language, our model develops support for over 100 languages without explicit multilingual pretraining or tuning of the text encoder. Such emergent multimodal and multilingual properties are gained efficiently, preserving previously learned knowledge at a training cost comparable to that of a monolingual model. Our strategy achieves up to a 14.24 percentage points improvement in R@1 audio-to-text retrieval, outperforming state-of-the-art multimodal models -- all without the heavy computational cost of retraining across every modality and language.

We present AstroCLIP, a strategy to facilitate the construction of astronomical foundation models that bridge the gap between diverse observational modalities. We demonstrate that a cross-modal contrastive learning approach between images and optical spectra of galaxies yields highly informative embeddings of both modalities. In particular, we apply our method on multi-band images and optical spectra from the Dark Energy Spectroscopic Instrument (DESI), and show that: (1) these embeddings are well-aligned between modalities and can be used for accurate cross-modal searches, and (2) these embeddings encode valuable physical information about the galaxies -- in particular redshift and stellar mass -- that can be used to achieve competitive zero- and few- shot predictions without further finetuning. Additionally, in the process of developing our approach, we also construct a novel, transformer-based model and pretraining approach for processing galaxy spectra.

We propose Unicoder-VL, a universal encoder that aims to learn joint representations of vision and language in a pre-training manner. Borrow ideas from cross-lingual pre-trained models, such as XLM and Unicoder, both visual and linguistic contents are fed into a multi-layer Transformer for the cross-modal pre-training, where three pre-trained tasks are employed, including Masked Language Modeling (MLM), Masked Object Classification (MOC) and Visual-linguistic Matching (VLM). The first two tasks learn context-aware representations for input tokens based on linguistic and visual contents jointly. The last task tries to predict whether an image and a text describe each other. After pretraining on large-scale image-caption pairs, we transfer Unicoder-VL to caption-based image-text retrieval and visual commonsense reasoning, with just one additional output layer. We achieve state-of-the-art or comparable results on both two tasks and show the powerful ability of the cross-modal pre-training.

Concept customization typically binds rare tokens to a target concept. Unfortunately, these approaches often suffer from unstable performance as the pretraining data seldom contains these rare tokens. Meanwhile, these rare tokens fail to convey the inherent knowledge of the target concept. Consequently, we introduce Knowledge-aware Concept Customization, a novel task aiming at binding diverse textual knowledge to target visual concepts. This task requires the model to identify the knowledge within the text prompt to perform high-fidelity customized generation. Meanwhile, the model should efficiently bind all the textual knowledge to the target concept. Therefore, we propose MoKus, a novel framework for knowledge-aware concept customization. Our framework relies on a key observation: cross-modal knowledge transfer, where modifying knowledge within the text modality naturally transfers to the visual modality during generation. Inspired by this observation, MoKus contains two stages: (1) In visual concept learning, we first learn the anchor representation to store the visual information of the target concept. (2) In textual knowledge updating, we update the answer for the knowledge queries to the anchor representation, enabling high-fidelity customized generation. To further comprehensively evaluate our proposed MoKus on the new task, we introduce the first benchmark for knowledge-aware concept customization: KnowCusBench. Extensive evaluations have demonstrated that MoKus outperforms state-of-the-art methods. Moreover, the cross-model knowledge transfer allows MoKus to be easily extended to other knowledge-aware applications like virtual concept creation and concept erasure. We also demonstrate the capability of our method to achieve improvements on world knowledge benchmarks.

Vision-Language Models (VLMs), such as CLIP, exhibit strong image-text comprehension abilities, facilitating advances in several downstream tasks such as zero-shot image classification, image-text retrieval, and text-to-image generation. However, the compositional reasoning abilities of existing VLMs remains subpar. The root of this limitation lies in the inadequate alignment between the images and captions in the pretraining datasets. Additionally, the current contrastive learning objective fails to focus on fine-grained grounding components like relations, actions, and attributes, resulting in "bag-of-words" representations. We introduce a simple and effective method to improve compositional reasoning in VLMs. Our method better leverages available datasets by refining and expanding the standard image-text contrastive learning framework. Our approach does not require specific annotations and does not incur extra parameters. When integrated with CLIP, our technique yields notable improvement over state-of-the-art baselines across five vision-language compositional benchmarks. We open-source our code at https://github.com/lezhang7/Enhance-FineGrained.

We propose to build omni-modal intelligence, which is capable of understanding any modality and learning universal representations. In specific, we propose a scalable pretraining paradigm, named Multimodal Context (MiCo), which can scale up the numbers of modalities and amount of data, together with the model parameters, in the pretraining process. With MiCo, the pretrained models show significant emergent abilities in multimodal learning, which are evaluated on the following tasks: i) single-modality perception benchmarks of 10 different modalities, ii) 25 cross-modality understanding tasks of retrieval, question-answering, captioning, and iii) 18 multimodal large language model benchmarks. Our models establish 37 new records for state-of-the-art performance. We hope that our research could contribute to the development of omni-modal intelligence. Code and Models are at https://github.com/invictus717/MiCo

Large Language Models (LLMs) demonstrate remarkable generalizability across diverse tasks, yet genomic foundation models (GFMs) still require separate finetuning for each downstream application, creating significant overhead as model sizes grow. Moreover, existing GFMs are constrained by rigid output formats, limiting their applicability to various genomic tasks. In this work, we revisit the transformer-based auto-regressive models and introduce Omni-DNA, a family of cross-modal multi-task models ranging from 20 million to 1 billion parameters. Our approach consists of two stages: (i) pretraining on DNA sequences with next token prediction objective, and (ii) expanding the multi-modal task-specific tokens and finetuning for multiple downstream tasks simultaneously. When evaluated on the Nucleotide Transformer and GB benchmarks, Omni-DNA achieves state-of-the-art performance on 18 out of 26 tasks. Through multi-task finetuning, Omni-DNA addresses 10 acetylation and methylation tasks at once, surpassing models trained on each task individually. Finally, we design two complex genomic tasks, DNA2Function and Needle-in-DNA, which map DNA sequences to textual functional descriptions and images, respectively, indicating Omni-DNA's cross-modal capabilities to broaden the scope of genomic applications. All the models are available through https://huggingface.co/collections/zehui127

Recently, large-scale diffusion models, e.g., Stable diffusion and DallE2, have shown remarkable results on image synthesis. On the other hand, large-scale cross-modal pre-trained models (e.g., CLIP, ALIGN, and FILIP) are competent for various downstream tasks by learning to align vision and language embeddings. In this paper, we explore the possibility of jointly modeling generation and discrimination. Specifically, we propose DiffDis to unify the cross-modal generative and discriminative pretraining into one single framework under the diffusion process. DiffDis first formulates the image-text discriminative problem as a generative diffusion process of the text embedding from the text encoder conditioned on the image. Then, we propose a novel dual-stream network architecture, which fuses the noisy text embedding with the knowledge of latent images from different scales for image-text discriminative learning. Moreover, the generative and discriminative tasks can efficiently share the image-branch network structure in the multi-modality model. Benefiting from diffusion-based unified training, DiffDis achieves both better generation ability and cross-modal semantic alignment in one architecture. Experimental results show that DiffDis outperforms single-task models on both the image generation and the image-text discriminative tasks, e.g., 1.65% improvement on average accuracy of zero-shot classification over 12 datasets and 2.42 improvement on FID of zero-shot image synthesis.

Vision-Language Pretraining (VLP) has achieved remarkable success across various downstream tasks, but such gains are largely driven by scaling up on training data. Yet, literature methods treat image-text pairs as isolated training examples; this neglects the rich relational structure naturally present in many domains, such as e-commerce product co-purchase graphs and social recommendation networks. Inspired by neuroscientific evidence that human encodes knowledge as relationship cognitive maps, we introduce Structure-aware Language-Image Pretraining (SLIP). SLIP integrates a structural contrastive loss to align modalities while also modeling relationships between neighboring entities in a structured graph. To support this paradigm, we construct a large-scale Amazon Product Co-purchase Multimodal Graph Dataset, enabling structured cross-modality supervision at scale. Experiment results show that SLIP consistently outperforms CLIP on cross-modal retrieval and classification tasks in both zero-shot and few-shot settings, showing the value of relational supervision for cross-modal alignment.

Multimodal Large Language Models (MLLMs) have seen growing adoption across various scientific disciplines. These advancements encourage the investigation of molecule-text modeling within synthetic chemistry, a field dedicated to designing and conducting chemical reactions to synthesize new compounds with desired properties and applications. Current approaches, however, often neglect the critical role of multiple molecule graph interaction in understanding chemical reactions, leading to suboptimal performance in synthetic chemistry tasks. This study introduces PRESTO(Progressive Pretraining Enhances Synthetic Chemistry Outcomes), a new framework that bridges the molecule-text modality gap by integrating a comprehensive benchmark of pretraining strategies and dataset configurations. It progressively improves multimodal LLMs through cross-modal alignment and multi-graph understanding. Our extensive experiments demonstrate that PRESTO offers competitive results in downstream synthetic chemistry tasks. The code can be found at https://github.com/IDEA-XL/PRESTO.

Among the ever-evolving development of vision-language models, contrastive language-image pretraining (CLIP) has set new benchmarks in many downstream tasks such as zero-shot classifications by leveraging self-supervised contrastive learning on large amounts of text-image pairs. However, its dependency on rigid one-to-one mappings overlooks the complex and often multifaceted relationships between and within texts and images. To this end, we introduce RankCLIP, a novel pretraining method that extends beyond the rigid one-to-one matching framework of CLIP and its variants. By leveraging both in-modal and cross-modal ranking consistency, RankCLIP improves the alignment process, enabling it to capture the nuanced many-to-many relationships between and within each modality. Through comprehensive experiments, we demonstrate the enhanced capability of RankCLIP to effectively improve performance across various downstream tasks, notably achieving significant gains in zero-shot classifications over state-of-the-art methods, underscoring the potential of RankCLIP in further advancing vision-language pretraining.

Electrocardiograms (ECGs) play a vital role in monitoring cardiac health and diagnosing heart diseases. However, traditional deep learning approaches for ECG analysis rely heavily on large-scale manual annotations, which are both time-consuming and resource-intensive to obtain. To overcome this limitation, self-supervised learning (SSL) has emerged as a promising alternative, enabling the extraction of robust ECG representations that can be efficiently transferred to various downstream tasks. While previous studies have explored SSL for ECG pretraining and multi-modal ECG-language alignment, they often fail to capture the multi-scale nature of ECG signals. As a result, these methods struggle to learn generalized representations due to their inability to model the hierarchical structure of ECG data. To address this gap, we introduce MELP, a novel Multi-scale ECG-Language Pretraining (MELP) model that fully leverages hierarchical supervision from ECG-text pairs. MELP first pretrains a cardiology-specific language model to enhance its understanding of clinical text. It then applies three levels of cross-modal supervision-at the token, beat, and rhythm levels-to align ECG signals with textual reports, capturing structured information across different time scales. We evaluate MELP on three public ECG datasets across multiple tasks, including zero-shot ECG classification, linear probing, and transfer learning. Experimental results demonstrate that MELP outperforms existing SSL methods, underscoring its effectiveness and adaptability across diverse clinical applications. Our code is available at https://github.com/HKU-MedAI/MELP.

Surgical video-language pretraining (VLP) faces unique challenges due to the knowledge domain gap and the scarcity of multi-modal data. This study aims to bridge the gap by addressing issues regarding textual information loss in surgical lecture videos and the spatial-temporal challenges of surgical VLP. We propose a hierarchical knowledge augmentation approach and a novel Procedure-Encoded Surgical Knowledge-Augmented Video-Language Pretraining (PeskaVLP) framework to tackle these issues. The knowledge augmentation uses large language models (LLM) for refining and enriching surgical concepts, thus providing comprehensive language supervision and reducing the risk of overfitting. PeskaVLP combines language supervision with visual self-supervision, constructing hard negative samples and employing a Dynamic Time Warping (DTW) based loss function to effectively comprehend the cross-modal procedural alignment. Extensive experiments on multiple public surgical scene understanding and cross-modal retrieval datasets show that our proposed method significantly improves zero-shot transferring performance and offers a generalist visual representation for further advancements in surgical scene understanding.The code is available at https://github.com/CAMMA-public/SurgVLP

While recent work shows promising results in expanding the capabilities of large language models (LLM) to directly understand and synthesize speech, an LLM-based strategy for modeling spoken dialogs remains elusive and calls for further investigation. This work proposes an extensive speech-text LLM framework, named the Unified Spoken Dialog Model (USDM), to generate coherent spoken responses with organic prosodic features relevant to the given input speech without relying on automatic speech recognition (ASR) or text-to-speech (TTS) solutions. Our approach employs a multi-step speech-text inference scheme that leverages chain-of-reasoning capabilities exhibited by the underlying LLM. We also propose a generalized speech-text pretraining scheme that helps with capturing cross-modal semantics. Automatic and human evaluations show that the proposed approach is effective in generating natural-sounding spoken responses, outperforming both prior and cascaded baselines. Detailed comparative studies reveal that, despite the cascaded approach being stronger in individual components, the joint speech-text modeling improves robustness against recognition errors and speech quality. Demo is available at https://unifiedsdm.github.io.

Continuous Glucose Monitoring (CGM) can detect early metabolic subphenotypes (insulin resistance, IR; β-cell dysfunction), but population-scale deployment faces two coupled problems. First, the same physiological state appears through multiple views (CGM time series, venous OGTT, Glucodensity summaries), so single-view representations fail to transfer when deployment shifts the modality or setting. Second, baselines perform inconsistently across these shifts. Both problems point to one remedy: representations that abstract away from any single view to capture higher-level temporal and distributional structure. We propose CGM-JEPA, a self-supervised pretraining framework which predicts masked latent representations rather than raw values, yielding abstraction that transfers across modalities. X-CGM-JEPA adds a masked Glucodensity cross-view objective for complementary distributional information. We pretrain on sim389k unlabeled CGM readings from 228 subjects and evaluate on two clinical cohorts (N=27 and N=17 public-release subsets) across three regimes (cohort generalization, venous-to-CGM transfer, home CGM) under 20-iteration times 2-fold cross-validation. X-CGM-JEPA ranks first or second on AUROC for both endpoints across all three regimes while no baseline does, exceeding the strongest baseline by up to +6.5 pp in cohort generalization and +3.6 pp in venous-to-CGM transfer (paired Wilcoxon, p<0.001). Under modality shift, it matches mean AUROC while redistributing toward weaker subgroups (ethnicity AUROC gap shrinks 25-54%); on sparse in-domain venous data, the distributional view lifts label-aware clustering (ARI +39%, NMI +40%). Code and weights: https://github.com/cruiseresearchgroup/CGM-JEPA

Despite recent advances in medical vision-language pretraining, existing models still struggle to capture the diagnostic workflow: radiographs are typically treated as context-agnostic images, while radiologists' gaze -- a crucial cue for visual reasoning -- remains largely underexplored by existing methods. These limitations hinder the modeling of disease-specific patterns and weaken cross-modal alignment. To bridge this gap, we introduce CoGaze, a Context- and Gaze-guided vision-language pretraining framework for chest X-rays. We first propose a context-infused vision encoder that models how radiologists integrate clinical context -- including patient history, symptoms, and diagnostic intent -- to guide diagnostic reasoning. We then present a multi-level supervision paradigm that (1) enforces intra- and inter-modal semantic alignment through hybrid-positive contrastive learning, (2) injects diagnostic priors via disease-aware cross-modal representation learning, and (3) leverages radiologists' gaze as probabilistic priors to guide attention toward diagnostically salient regions. Extensive experiments demonstrate that CoGaze consistently outperforms state-of-the-art methods across diverse tasks, achieving up to +2.0% CheXbertF1 and +1.2% BLEU2 for free-text and structured report generation, +23.2% AUROC for zero-shot classification, and +12.2% Precision@1 for image-text retrieval. Code is available at https://github.com/mk-runner/CoGaze.

With recent progress in joint modeling of visual and textual representations, Vision-Language Pretraining (VLP) has achieved impressive performance on many multimodal downstream tasks. However, the requirement for expensive annotations including clean image captions and regional labels limits the scalability of existing approaches, and complicates the pretraining procedure with the introduction of multiple dataset-specific objectives. In this work, we relax these constraints and present a minimalist pretraining framework, named Simple Visual Language Model (SimVLM). Unlike prior work, SimVLM reduces the training complexity by exploiting large-scale weak supervision, and is trained end-to-end with a single prefix language modeling objective. Without utilizing extra data or task-specific customization, the resulting model significantly outperforms previous pretraining methods and achieves new state-of-the-art results on a wide range of discriminative and generative vision-language benchmarks, including VQA (+3.74% vqa-score), NLVR2 (+1.17% accuracy), SNLI-VE (+1.37% accuracy) and image captioning tasks (+10.1% average CIDEr score). Furthermore, we demonstrate that SimVLM acquires strong generalization and transfer ability, enabling zero-shot behavior including open-ended visual question answering and cross-modality transfer.

Building video-language foundation models is costly and difficult due to the redundant nature of video data and the lack of high-quality video-language datasets. In this paper, we propose an efficient framework to harvest video foundation models from image ones. Our method is intuitively simple by randomly dropping input video patches and masking out input text during the post-pretraining procedure. The patch dropping boosts the training efficiency significantly and text masking enforces the learning of cross-modal fusion. We conduct extensive experiments to validate the effectiveness of our method on a wide range of video-language downstream tasks including various zero-shot tasks, video question answering, and video-text retrieval. Despite its simplicity, our method achieves state-of-the-art performances, which are comparable to some heavily pretrained video foundation models. Our method is extremely efficient and can be trained in less than one day on 8 GPUs, requiring only WebVid-10M as pretraining data. We hope our method can serve as a simple yet strong counterpart for prevalent video foundation models, provide useful insights when building them, and make large pretrained models more accessible and sustainable. This is part of the InternVideo project https://github.com/OpenGVLab/InternVideo.

Recent progress in large-scale CLIP-like vision-language models(VLMs) has greatly advanced medical image analysis. However, most existing medical VLMs still rely on coarse image-text contrastive objectives and fail to capture the systematic visual knowledge encoded in well-defined medical phenotype ontologies. To address this gap, we construct PhenoKG, the first large-scale, phenotype-centric multimodal knowledge graph that encompasses over 520K high-quality image-text pairs linked to more than 3,000 phenotypes. Building upon PhenoKG, we propose PhenoLIP, a novel pretraining framework that explicitly incorporates structured phenotype knowledge into medical VLMs through a two-stage process. We first learn a knowledge-enhanced phenotype embedding space from textual ontology data and then distill this structured knowledge into multimodal pretraining via a teacher-guided knowledge distillation objective. To support evaluation, we further introduce PhenoBench, an expert-verified benchmark designed for phenotype recognition, comprising over 7,800 image--caption pairs covering more than 1,000 phenotypes. Extensive experiments demonstrate that PhenoLIP outperforms previous state-of-the-art baselines, improving upon BiomedCLIP in phenotype classification accuracy by 8.85\% and BIOMEDICA in cross-modal retrieval by 15.03%, underscoring the value of integrating phenotype-centric priors into medical VLMs for structured and interpretable medical image understanding.

Mainstream 3D representation learning approaches are built upon contrastive or generative modeling pretext tasks, where great improvements in performance on various downstream tasks have been achieved. However, we find these two paradigms have different characteristics: (i) contrastive models are data-hungry that suffer from a representation over-fitting issue; (ii) generative models have a data filling issue that shows inferior data scaling capacity compared to contrastive models. This motivates us to learn 3D representations by sharing the merits of both paradigms, which is non-trivial due to the pattern difference between the two paradigms. In this paper, we propose Contrast with Reconstruct (ReCon) that unifies these two paradigms. ReCon is trained to learn from both generative modeling teachers and single/cross-modal contrastive teachers through ensemble distillation, where the generative student guides the contrastive student. An encoder-decoder style ReCon-block is proposed that transfers knowledge through cross attention with stop-gradient, which avoids pretraining over-fitting and pattern difference issues. ReCon achieves a new state-of-the-art in 3D representation learning, e.g., 91.26% accuracy on ScanObjectNN. Codes have been released at https://github.com/qizekun/ReCon.

Dermatological diagnosis represents a complex multimodal challenge that requires integrating visual features with specialized clinical knowledge. While vision-language pretraining (VLP) has advanced medical AI, its effectiveness in dermatology is limited by text length constraints and the lack of structured texts. In this paper, we introduce MAKE, a Multi-Aspect Knowledge-Enhanced vision-language pretraining framework for zero-shot dermatological tasks. Recognizing that comprehensive dermatological descriptions require multiple knowledge aspects that exceed standard text constraints, our framework introduces: (1) a multi-aspect contrastive learning strategy that decomposes clinical narratives into knowledge-enhanced sub-texts through large language models, (2) a fine-grained alignment mechanism that connects subcaptions with diagnostically relevant image features, and (3) a diagnosis-guided weighting scheme that adaptively prioritizes different sub-captions based on clinical significance prior. Through pretraining on 403,563 dermatological image-text pairs collected from education resources, MAKE significantly outperforms state-of-the-art VLP models on eight datasets across zero-shot skin disease classification, concept annotation, and cross-modal retrieval tasks. Our code will be made publicly available at https: //github.com/SiyuanYan1/MAKE.

Learning computer vision models from (and for) movies has a long-standing history. While great progress has been attained, there is still a need for a pretrained multimodal model that can perform well in the ever-growing set of movie understanding tasks the community has been establishing. In this work, we introduce Long-range Multimodal Pretraining, a strategy, and a model that leverages movie data to train transferable multimodal and cross-modal encoders. Our key idea is to learn from all modalities in a movie by observing and extracting relationships over a long-range. After pretraining, we run ablation studies on the LVU benchmark and validate our modeling choices and the importance of learning from long-range time spans. Our model achieves state-of-the-art on several LVU tasks while being much more data efficient than previous works. Finally, we evaluate our model's transferability by setting a new state-of-the-art in five different benchmarks.

Contrastive Language-Image Pre-training (CLIP) relies on Vision Transformers whose attention mechanism is susceptible to spurious correlations, and scales quadratically with resolution. To address these limitations, We present CLIMP, the first fully Mamba-based contrastive vision-language model that replaces both the vision and text encoders with Mamba. The new architecture encodes sequential structure in both vision and language, with VMamba capturing visual spatial inductive biases, reducing reliance on spurious correlations and producing an embedding space favorable for cross-modal retrieval and out-of-distribution robustness-surpassing OpenAI's CLIP-ViT-B by 7.5% on ImageNet-O. CLIMP naturally supports variable input resolutions without positional encoding interpolation or specialized training, achieving up to 6.6% higher retrieval accuracy at 16x training resolution while using 5x less memory and 1.8x fewer FLOPs. The autoregressive text encoder further overcomes CLIP's fixed context limitation, enabling dense captioning retrieval. Our findings suggest that Mamba exhibits advantageous properties for vision-language learning, making it a compelling alternative to Transformer-based CLIP.

Contrastive Language-Image Pretraining (CLIP) has demonstrated strong generalization for vision-language tasks in computer vision and medical domains, yet its text encoder accepts only up to 77 tokens, which limits its ability to represent long and information-rich radiology reports. Recent adaptations using domain-specific encoders, such as PubMedBERT or ClinicalBERT, mitigate this issue by leveraging medical corpora, but remain constrained by their limited input length (typically 512 tokens) and relatively shallow semantic understanding. To address these limitations, we propose QwenCLIP, a vision-language framework that replaces CLIP's text encoder with a large language model (LLM)-based embedding module (e.g., Qwen3-Embedding) and introduces learnable prompts to enhance cross-modal alignment. By leveraging the extended context window and richer representations of LLMs, QwenCLIP captures comprehensive medical semantics from long-form clinical text, substantially improving medical image-text alignment and downstream performance on radiology benchmarks. Our code is publicly available at https://github.com/Wxy-24/QwenCLIP.

A big convergence of language, vision, and multimodal pretraining is emerging. In this work, we introduce a general-purpose multimodal foundation model BEiT-3, which achieves state-of-the-art transfer performance on both vision and vision-language tasks. Specifically, we advance the big convergence from three aspects: backbone architecture, pretraining task, and model scaling up. We introduce Multiway Transformers for general-purpose modeling, where the modular architecture enables both deep fusion and modality-specific encoding. Based on the shared backbone, we perform masked "language" modeling on images (Imglish), texts (English), and image-text pairs ("parallel sentences") in a unified manner. Experimental results show that BEiT-3 obtains state-of-the-art performance on object detection (COCO), semantic segmentation (ADE20K), image classification (ImageNet), visual reasoning (NLVR2), visual question answering (VQAv2), image captioning (COCO), and cross-modal retrieval (Flickr30K, COCO).

Vision-Language Pretraining (VLP) models have recently successfully facilitated many cross-modal downstream tasks. Most existing works evaluated their systems by comparing the fine-tuned downstream task performance. However, only average downstream task accuracy provides little information about the pros and cons of each VLP method, let alone provides insights on how the community can improve the systems in the future. Inspired by the CheckList for testing natural language processing, we exploit VL-CheckList, a novel framework to understand the capabilities of VLP models. The proposed method divides the image-texting ability of a VLP model into three categories: objects, attributes, and relations, and uses a novel taxonomy to further break down these three aspects. We conduct comprehensive studies to analyze seven recently popular VLP models via the proposed framework. Results confirm the effectiveness of the proposed method by revealing fine-grained differences among the compared models that were not visible from downstream task-only evaluation. Further results show promising research direction in building better VLP models. Our data and code are available at: https://github.com/om-ai-lab/VL-CheckList.

Dense image captioning is critical for cross-modal alignment in vision-language pretraining and text-to-image generation, but scaling expert-quality annotations is prohibitively expensive. While synthetic captioning via strong vision-language models (VLMs) is a practical alternative, supervised distillation often yields limited output diversity and weak generalization. Reinforcement learning (RL) could overcome these limitations, but its successes have so far been concentrated in verifiable domains that rely on deterministic checkers -- a luxury not available in open-ended captioning. We address this bottleneck with RubiCap, a novel RL framework that derives fine-grained, sample-specific reward signals from LLM-written rubrics. RubiCap first assembles a diverse committee of candidate captions, then employs an LLM rubric writer to extract consensus strengths and diagnose deficiencies in the current policy. These insights are converted into explicit evaluation criteria, enabling an LLM judge to decompose holistic quality assessment and replace coarse scalar rewards with structured, multi-faceted evaluations. Across extensive benchmarks, RubiCap achieves the highest win rates on CapArena, outperforming supervised distillation, prior RL methods, human-expert annotations, and GPT-4V-augmented outputs. On CaptionQA, it demonstrates superior word efficiency: our 7B model matches Qwen2.5-VL-32B-Instruct, and our 3B model surpasses its 7B counterpart. Remarkably, using the compact RubiCap-3B as a captioner produces stronger pretrained VLMs than those trained on captions from proprietary models.

The increasing availability of multimodal data across text, tables, and images presents new challenges for developing models capable of complex cross-modal reasoning. Existing methods for Multimodal Multi-hop Question Answering (MMQA) often suffer from limited reasoning capabilities, reliance on modality conversion, and inadequate alignment between visual and textual representations. To address these limitations, this paper introduces Vision-Language Multimodal Transformer (VLMT), a unified architecture that integrates a transformer-based vision encoder with a sequence-to-sequence language model. VLMT employs a direct token-level injection mechanism to fuse visual and textual inputs within a shared embedding space, eliminating the need for intermediate projection layers. To enhance cross-modal alignment and reasoning, a three-stage pretraining strategy is proposed to progressively align vision-language representations and improve the model's capacity for multimodal understanding. Based on the pretrained backbone, two task-specific modules are instantiated to form a two-stage MMQA framework: a multimodal reranker that predicts document relevance scores and utilizes a relative threshold with top-k strategy for context retrieval, and a multimodal question answering model that generates contextually grounded answers based on the retrieved evidence. Comprehensive experiments on two benchmark datasets demonstrate the effectiveness of the proposed approach. On MultimodalQA validation set, VLMT-Large achieves 76.5% Exact Match and 80.1% F1, outperforming the previous state-of-the-art by +9.1% in Exact Match and +8.8% in F1. On WebQA, it attains a QA score of 47.6, surpassing prior models such as PERQA by +3.2. These results highlight VLMT's strong capabilities in multimodal reasoning and its potential to advance real-world information retrieval and question answering systems.

Although the vision-and-language pretraining (VLP) equipped cross-modal image-text retrieval (ITR) has achieved remarkable progress in the past two years, it suffers from a major drawback: the ever-increasing size of VLP models restricts its deployment to real-world search scenarios (where the high latency is unacceptable). To alleviate this problem, we present a novel plug-in dynamic contrastive distillation (DCD) framework to compress the large VLP models for the ITR task. Technically, we face the following two challenges: 1) the typical uni-modal metric learning approach is difficult to directly apply to the cross-modal tasks, due to the limited GPU memory to optimize too many negative samples during handling cross-modal fusion features. 2) it is inefficient to static optimize the student network from different hard samples, which have different effects on distillation learning and student network optimization. We try to overcome these challenges from two points. First, to achieve multi-modal contrastive learning, and balance the training costs and effects, we propose to use a teacher network to estimate the difficult samples for students, making the students absorb the powerful knowledge from pre-trained teachers, and master the knowledge from hard samples. Second, to dynamic learn from hard sample pairs, we propose dynamic distillation to dynamically learn samples of different difficulties, from the perspective of better balancing the difficulty of knowledge and students' self-learning ability. We successfully apply our proposed DCD strategy to two state-of-the-art vision-language pretrained models, i.e. ViLT and METER. Extensive experiments on MS-COCO and Flickr30K benchmarks show the effectiveness and efficiency of our DCD framework. Encouragingly, we can speed up the inference at least 129times compared to the existing ITR models.

Contrastive Language-Image Pretraining (CLIP) model has exhibited remarkable efficacy in establishing cross-modal connections between texts and images, yielding impressive performance across a broad spectrum of downstream applications through fine-tuning. However, for generalization tasks, the current fine-tuning methods for CLIP, such as CoOp and CoCoOp, demonstrate relatively low performance on some fine-grained datasets. We recognize the underlying reason is that these previous methods only projected global features into the prompt, neglecting the various visual concepts, such as colors, shapes, and sizes, which are naturally transferable across domains and play a crucial role in generalization tasks. To address this issue, in this work, we propose Concept-Guided Prompt Learning (CPL) for vision-language models. Specifically, we leverage the well-learned knowledge of CLIP to create a visual concept cache to enable concept-guided prompting. In order to refine the text features, we further develop a projector that transforms multi-level visual features into text features. We observe that this concept-guided prompt learning approach is able to achieve enhanced consistency between visual and linguistic modalities. Extensive experimental results demonstrate that our CPL method significantly improves generalization capabilities compared to the current state-of-the-art methods.

Pedestrian Attribute Recognition (PAR) involves predicting fine-grained attributes such as clothing color, gender, and accessories from pedestrian imagery, yet is hindered by severe class imbalance, intricate attribute co-dependencies, and domain shifts. We introduce VLM-PAR, a modular vision-language framework built on frozen SigLIP 2 multilingual encoders. By first aligning image and prompt embeddings via refining visual features through a compact cross-attention fusion, VLM-PAR achieves significant accuracy improvement on the highly imbalanced PA100K benchmark, setting a new state-of-the-art performance, while also delivering significant gains in mean accuracy across PETA and Market-1501 benchmarks. These results underscore the efficacy of integrating large-scale vision-language pretraining with targeted cross-modal refinement to overcome imbalance and generalization challenges in PAR.

Affordance segmentation aims to decompose 3D objects into parts that serve distinct functional roles, enabling models to reason about object interactions rather than mere recognition. Existing methods, mostly following the paradigm of 3D semantic segmentation or prompt-based frameworks, struggle when geometric cues are weak or ambiguous, as sparse point clouds provide limited functional information. To overcome this limitation, we leverage the rich semantic knowledge embedded in large-scale 2D Vision Foundation Models (VFMs) to guide 3D representation learning through a cross-modal alignment mechanism. Specifically, we propose Cross-Modal Affinity Transfer (CMAT), a pretraining strategy that compels the 3D encoder to align with the semantic structures induced by lifted 2D features. CMAT is driven by a core affinity alignment objective, supported by two auxiliary losses, geometric reconstruction and feature diversity, which together encourage structured and discriminative feature learning. Built upon the CMAT-pretrained backbone, we employ a lightweight affordance segmentor that injects text or visual prompts into the learned 3D space through an efficient cross-attention interface, enabling dense and prompt-aware affordance prediction while preserving the semantic organization established during pretraining. Extensive experiments demonstrate consistent improvements over previous state-of-the-art methods in both accuracy and efficiency.

Medical image retrieval is essential for clinical decision-making and translational research, relying on discriminative visual representations. Yet, current methods remain fragmented, relying on separate architectures and training strategies for 2D, 3D, and video-based medical data. This modality-specific design hampers scalability and inhibits the development of unified representations. To enable unified learning, we curate a large-scale hybrid-modality dataset comprising 867,653 medical imaging samples, including 2D X-rays and ultrasounds, RGB endoscopy videos, and 3D CT scans. Leveraging this dataset, we train M3Ret, a unified visual encoder without any modality-specific customization. It successfully learns transferable representations using both generative (MAE) and contrastive (SimDINO) self-supervised learning (SSL) paradigms. Our approach sets a new state-of-the-art in zero-shot image-to-image retrieval across all individual modalities, surpassing strong baselines such as DINOv3 and the text-supervised BMC-CLIP. More remarkably, strong cross-modal alignment emerges without paired data, and the model generalizes to unseen MRI tasks, despite never observing MRI during pretraining, demonstrating the generalizability of purely visual self-supervision to unseen modalities. Comprehensive analyses further validate the scalability of our framework across model and data sizes. These findings deliver a promising signal to the medical imaging community, positioning M3Ret as a step toward foundation models for visual SSL in multimodal medical image understanding.

Recent multimodal embedding approaches leveraging multimodal large language models (MLLMs) fine-tuned with contrastive learning (CL) have shown promising results, yet the underlying reasons behind their superiority remain underexplored. This work argues that a crucial advantage of MLLM-based approaches stems from implicit cross-modal alignment achieved during generative pretraining, where the language decoder learns to exploit multimodal signals within a shared representation space for generating unimodal outputs. Through analysis of anisotropy and kernel similarity structure, we empirically confirm that latent alignment emerges within MLLM representations, allowing CL to serve as a lightweight refinement stage. Leveraging this insight, we propose a Language-Centric Omnimodal Embedding framework, termed LCO-Emb. Extensive experiments across diverse backbones and benchmarks demonstrate its effectiveness, achieving state-of-the-art performance across modalities. Furthermore, we identify a Generation-Representation Scaling Law (GRSL), showing that the representational capabilities gained through contrastive refinement scales positively with the MLLM's generative capabilities. This suggests that improving generative abilities evolves as an effective paradigm for enhancing representation quality. We provide a theoretical explanation of GRSL, which formally links the MLLM's generative quality to the upper bound on its representation performance, and validate it on a challenging, low-resource visual-document retrieval task, showing that continual generative pretraining before CL can further enhance the potential of a model's embedding capabilities. Codes, models, and resources are available at https://github.com/LCO-Embedding/LCO-Embedding.

Large Language Models (LLMs) have driven significant progress, yet their growing parameter counts and context windows incur prohibitive compute, energy, and monetary costs. We introduce EfficientLLM, a novel benchmark and the first comprehensive empirical study evaluating efficiency techniques for LLMs at scale. Conducted on a production-class cluster (48xGH200, 8xH200 GPUs), our study systematically explores three key axes: (1) architecture pretraining (efficient attention variants: MQA, GQA, MLA, NSA; sparse Mixture-of-Experts (MoE)), (2) fine-tuning (parameter-efficient methods: LoRA, RSLoRA, DoRA), and (3) inference (quantization methods: int4, float16). We define six fine-grained metrics (Memory Utilization, Compute Utilization, Latency, Throughput, Energy Consumption, Compression Rate) to capture hardware saturation, latency-throughput balance, and carbon cost. Evaluating over 100 model-technique pairs (0.5B-72B parameters), we derive three core insights: (i) Efficiency involves quantifiable trade-offs: no single method is universally optimal; e.g., MoE reduces FLOPs and improves accuracy but increases VRAM by 40%, while int4 quantization cuts memory/energy by up to 3.9x at a 3-5% accuracy drop. (ii) Optima are task- and scale-dependent: MQA offers optimal memory-latency trade-offs for constrained devices, MLA achieves lowest perplexity for quality-critical tasks, and RSLoRA surpasses LoRA efficiency only beyond 14B parameters. (iii) Techniques generalize across modalities: we extend evaluations to Large Vision Models (Stable Diffusion 3.5, Wan 2.1) and Vision-Language Models (Qwen2.5-VL), confirming effective transferability. By open-sourcing datasets, evaluation pipelines, and leaderboards, EfficientLLM provides essential guidance for researchers and engineers navigating the efficiency-performance landscape of next-generation foundation models.

We present SleepLM, a family of sleep-language foundation models that enable human sleep alignment, interpretation, and interaction with natural language. Despite the critical role of sleep, learning-based sleep analysis systems operate in closed label spaces (e.g., predefined stages or events) and fail to describe, query, or generalize to novel sleep phenomena. SleepLM bridges natural language and multimodal polysomnography, enabling language-grounded representations of sleep physiology. To support this alignment, we introduce a multilevel sleep caption generation pipeline that enables the curation of the first large-scale sleep-text dataset, comprising over 100K hours of data from more than 10,000 individuals. Furthermore, we present a unified pretraining objective that combines contrastive alignment, caption generation, and signal reconstruction to better capture physiological fidelity and cross-modal interactions. Extensive experiments on real-world sleep understanding tasks verify that SleepLM outperforms state-of-the-art in zero-shot and few-shot learning, cross-modal retrieval, and sleep captioning. Importantly, SleepLM also exhibits intriguing capabilities including language-guided event localization, targeted insight generation, and zero-shot generalization to unseen tasks. All code and data will be open-sourced.

Foundation models have recently achieved impressive success in computational pathology, demonstrating strong generalization across diverse histopathology tasks. However, existing models overlook the heterogeneous and non-uniform organization of pathological regions of interest (ROIs) because they rely on natural image backbones not tailored for tissue morphology. Consequently, they often fail to capture the coherent tissue architecture beyond isolated patches, limiting interpretability and clinical relevance. To address these challenges, we present Cross-modal Adaptive Region Encoder (CARE), a foundation model for pathology that automatically partitions WSIs into several morphologically relevant regions. Specifically, CARE employs a two-stage pretraining strategy: (1) a self-supervised unimodal pretraining stage that learns morphological representations from 34,277 whole-slide images (WSIs) without segmentation annotations, and (2) a cross-modal alignment stage that leverages RNA and protein profiles to refine the construction and representation of adaptive regions. This molecular guidance enables CARE to identify biologically relevant patterns and generate irregular yet coherent tissue regions, selecting the most representative area as ROI. CARE supports a broad range of pathology-related tasks, using either the ROI feature or the slide-level feature obtained by aggregating adaptive regions. Based on only one-tenth of the pretraining data typically used by mainstream foundation models, CARE achieves superior average performance across 33 downstream benchmarks, including morphological classification, molecular prediction, and survival analysis, and outperforms other foundation model baselines overall.

Integrating ground-level geospatial data with rich geographic context, like OpenStreetMap (OSM), into remote sensing (RS) foundation models (FMs) is essential for advancing geospatial intelligence and supporting a broad spectrum of tasks. However, modality gap between RS and OSM data, including differences in data structure, content, and spatial granularity, makes effective synergy highly challenging, and most existing RS FMs focus on imagery alone. To this end, this study presents GeoLink, a multimodal framework that leverages OSM data to enhance RS FM during both the pretraining and downstream task stages. Specifically, GeoLink enhances RS self-supervised pretraining using multi-granularity learning signals derived from OSM data, guided by cross-modal spatial correlations for information interaction and collaboration. It also introduces image mask-reconstruction to enable sparse input for efficient pretraining. For downstream tasks, GeoLink generates both unimodal and multimodal fine-grained encodings to support a wide range of applications, from common RS interpretation tasks like land cover classification to more comprehensive geographic tasks like urban function zone mapping. Extensive experiments show that incorporating OSM data during pretraining enhances the performance of the RS image encoder, while fusing RS and OSM data in downstream tasks improves the FM's adaptability to complex geographic scenarios. These results underscore the potential of multimodal synergy in advancing high-level geospatial artificial intelligence. Moreover, we find that spatial correlation plays a crucial role in enabling effective multimodal geospatial data integration. Code, checkpoints, and using examples are released at https://github.com/bailubin/GeoLink_NeurIPS2025

Multimodal question answering (QA) often requires identifying which video, audio, or sensor tokens are relevant to the question. Yet modality disagreements are common: off-camera speech, background noise, or motion outside the field of view often mislead fusion models that weight all streams equally. We present RAVEN, a unified QA architecture whose core is QuART, a query-conditioned cross-modal gating module that assigns scalar relevance scores to each token across modalities, enabling the model to amplify informative signals and suppress distractors before fusion. RAVEN is trained through a three-stage pipeline comprising unimodal pretraining, query-aligned fusion, and disagreement-oriented fine-tuning -- each stage targeting a distinct challenge in multi-modal reasoning: representation quality, cross-modal relevance, and robustness to modality mismatch. To support training and evaluation, we release AVS-QA, a dataset of 300K synchronized Audio--Video-Sensor streams paired with automatically generated question-answer pairs. Experimental results on seven multi-modal QA benchmarks -- including egocentric and exocentric tasks -- show that RAVEN achieves up to 14.5\% and 8.0\% gains in accuracy compared to state-of-the-art multi-modal large language models, respectively. Incorporating sensor data provides an additional 16.4\% boost, and the model remains robust under modality corruption, outperforming SOTA baselines by 50.23\%. Our code and dataset are available at https://github.com/BASHLab/RAVEN.

Audio-Visual Intelligence (AVI) has emerged as a central frontier in artificial intelligence, bridging auditory and visual modalities to enable machines that can perceive, generate, and interact in the multimodal real world. In the era of large foundation models, joint modeling of audio and vision has become increasingly crucial, i.e., not only for understanding but also for controllable generation and reasoning across dynamic, temporally grounded signals. Recent advances, such as Meta MovieGen and Google Veo-3, highlight the growing industrial and academic focus on unified audio-vision architectures that learn from massive multimodal data. However, despite rapid progress, the literature remains fragmented, spanning diverse tasks, inconsistent taxonomies, and heterogeneous evaluation practices that impede systematic comparison and knowledge integration. This survey provides the first comprehensive review of AVI through the lens of large foundation models. We establish a unified taxonomy covering the broad landscape of AVI tasks, ranging from understanding (e.g., speech recognition, sound localization) to generation (e.g., audio-driven video synthesis, video-to-audio) and interaction (e.g., dialogue, embodied, or agentic interfaces). We synthesize methodological foundations, including modality tokenization, cross-modal fusion, autoregressive and diffusion-based generation, large-scale pretraining, instruction alignment, and preference optimization. Furthermore, we curate representative datasets, benchmarks, and evaluation metrics, offering a structured comparison across task families and identifying open challenges in synchronization, spatial reasoning, controllability, and safety. By consolidating this rapidly expanding field into a coherent framework, this survey aims to serve as a foundational reference for future research on large-scale AVI.

Previous works show that noisy, web-crawled image-text pairs may limit vision-language pretraining like CLIP and propose learning with synthetic captions as a promising alternative. Our work continues this effort, introducing two simple yet effective designs to better leverage richly described synthetic captions. Firstly, by observing a strong inverse effect in learning with synthetic captions -- the short synthetic captions can generally lead to MUCH higher performance than full-length ones -- we therefore fed only partial synthetic captions to the text encoder. Secondly, we incorporate an autoregressive captioner to mimic the recaptioning process -- by conditioning on the paired image input and web-crawled text description, the captioner learns to predict the full-length synthetic caption generated by advanced MLLMs. Experiments show that our framework significantly improves zero-shot performance in cross-modal retrieval tasks, setting new SOTA results on MSCOCO and Flickr30K. Moreover, such trained vision encoders can enhance the visual capability of LLaVA, showing strong improvements on a range of MLLM benchmarks. Our project page is https://ucsc-vlaa.github.io/CLIPS/.

We present MolT5 - a self-supervised learning framework for pretraining models on a vast amount of unlabeled natural language text and molecule strings. MolT5 allows for new, useful, and challenging analogs of traditional vision-language tasks, such as molecule captioning and text-based de novo molecule generation (altogether: translation between molecules and language), which we explore for the first time. Since MolT5 pretrains models on single-modal data, it helps overcome the chemistry domain shortcoming of data scarcity. Furthermore, we consider several metrics, including a new cross-modal embedding-based metric, to evaluate the tasks of molecule captioning and text-based molecule generation. Our results show that MolT5-based models are able to generate outputs, both molecules and captions, which in many cases are high quality.

In this work, we explore a scalable way for building a general representation model toward unlimited modalities. We release ONE-PEACE, a highly extensible model with 4B parameters that can seamlessly align and integrate representations across vision, audio, and language modalities. The architecture of ONE-PEACE comprises modality adapters, shared self-attention layers, and modality FFNs. This design allows for the easy extension of new modalities by adding adapters and FFNs, while also enabling multi-modal fusion through self-attention layers. To pretrain ONE-PEACE, we develop two modality-agnostic pretraining tasks, cross-modal aligning contrast and intra-modal denoising contrast, which align the semantic space of different modalities and capture fine-grained details within modalities concurrently. With the scaling-friendly architecture and pretraining tasks, ONE-PEACE has the potential to expand to unlimited modalities. Without using any vision or language pretrained model for initialization, ONE-PEACE achieves leading results on a wide range of uni-modal and multi-modal tasks, including image classification (ImageNet), semantic segmentation (ADE20K), audio-text retrieval (AudioCaps, Clotho), audio classification (ESC-50, FSD50K, VGGSound), audio question answering (AVQA), image-text retrieval (MSCOCO, Flickr30K), and visual grounding (RefCOCO/+/g). Code is available at https://github.com/OFA-Sys/ONE-PEACE.

This paper presents PaLI-3, a smaller, faster, and stronger vision language model (VLM) that compares favorably to similar models that are 10x larger. As part of arriving at this strong performance, we compare Vision Transformer (ViT) models pretrained using classification objectives to contrastively (SigLIP) pretrained ones. We find that, while slightly underperforming on standard image classification benchmarks, SigLIP-based PaLI shows superior performance across various multimodal benchmarks, especially on localization and visually-situated text understanding. We scale the SigLIP image encoder up to 2 billion parameters, and achieves a new state-of-the-art on multilingual cross-modal retrieval. We hope that PaLI-3, at only 5B parameters, rekindles research on fundamental pieces of complex VLMs, and could fuel a new generation of scaled-up models.

Latent action representations learned from unlabeled videos have recently emerged as a promising paradigm for pretraining vision-language-action (VLA) models without explicit robot action supervision. However, latent actions derived solely from RGB observations primarily encode appearance-driven dynamics and lack explicit 3D geometric structure, which is essential for precise and contact-rich manipulation. To address this limitation, we introduce UniLACT, a transformer-based VLA model that incorporates geometric structure through depth-aware latent pretraining, enabling downstream policies to inherit stronger spatial priors. To facilitate this process, we propose UniLARN, a unified latent action learning framework based on inverse and forward dynamics objectives that learns a shared embedding space for RGB and depth while explicitly modeling their cross-modal interactions. This formulation produces modality-specific and unified latent action representations that serve as pseudo-labels for the depth-aware pretraining of UniLACT. Extensive experiments in both simulation and real-world settings demonstrate the effectiveness of depth-aware unified latent action representations. UniLACT consistently outperforms RGB-based latent action baselines under in-domain and out-of-domain pretraining regimes, as well as on both seen and unseen manipulation tasks.

Video-Action Models (VAMs) have emerged as a promising framework for embodied intelligence, learning implicit world dynamics from raw video streams to produce temporally consistent action predictions. Although such models demonstrate strong performance on long-horizon tasks through visual reasoning, they remain limited in contact-rich scenarios where critical interaction states are only partially observable from vision alone. In particular, fine-grained force modulation and contact transitions are not reliably encoded in visual tokens, leading to unstable or imprecise behaviors. To bridge this gap, we introduce the Video-Tactile Action Model (VTAM), a multimodal world modeling framework that incorporates tactile perception as a complementary grounding signal. VTAM augments a pretrained video transformer with tactile streams via a lightweight modality transfer finetuning, enabling efficient cross-modal representation learning without tactile-language paired data or independent tactile pretraining. To stabilize multimodal fusion, we introduce a tactile regularization loss that enforces balanced cross-modal attention, preventing visual latent dominance in the action model. VTAM demonstrates superior performance in contact-rich manipulation, maintaining a robust success rate of 90 percent on average. In challenging scenarios such as potato chip pick-and-place requiring high-fidelity force awareness, VTAM outperforms the pi 0.5 baseline by 80 percent. Our findings demonstrate that integrating tactile feedback is essential for correcting visual estimation errors in world action models, providing a scalable approach to physically grounded embodied foundation models.

Virtual try-on (VTON) has recently achieved impressive visual fidelity, but most existing systems require uploading personal photos to cloud-based GPUs, raising privacy concerns and limiting on-device deployment. To address this, we present Mobile-VTON, a high-quality, privacy-preserving framework that enables fully offline virtual try-on on commodity mobile devices using only a single user image and a garment image. Mobile-VTON introduces a modular TeacherNet-GarmentNet-TryonNet (TGT) architecture that integrates knowledge distillation, garment-conditioned generation, and garment alignment into a unified pipeline optimized for on-device efficiency. Within this framework, we propose a Feature-Guided Adversarial (FGA) Distillation strategy that combines teacher supervision with adversarial learning to better match real-world image distributions. GarmentNet is trained with a trajectory-consistency loss to preserve garment semantics across diffusion steps, while TryonNet uses latent concatenation and lightweight cross-modal conditioning to enable robust garment-to-person alignment without large-scale pretraining. By combining these components, Mobile-VTON achieves high-fidelity generation with low computational overhead. Experiments on VITON-HD and DressCode at 1024 x 768 show that it matches or outperforms strong server-based baselines while running entirely offline. These results demonstrate that high-quality VTON is not only feasible but also practical on-device, offering a secure solution for real-world applications. Code and project page are available at https://zhenchenwan.github.io/Mobile-VTON/.

Multimodal large language models (MLLMs) have demonstrated promising prospects in healthcare, particularly for addressing complex medical tasks, supporting multidisciplinary treatment (MDT), and enabling personalized precision medicine. However, their practical deployment faces critical challenges in resource efficiency, diagnostic accuracy, clinical considerations, and ethical privacy. To address these limitations, we propose Infi-Med, a comprehensive framework for medical MLLMs that introduces three key innovations: (1) a resource-efficient approach through curating and constructing high-quality supervised fine-tuning (SFT) datasets with minimal sample requirements, with a forward-looking design that extends to both pretraining and posttraining phases; (2) enhanced multimodal reasoning capabilities for cross-modal integration and clinical task understanding; and (3) a systematic evaluation system that assesses model performance across medical modalities and task types. Our experiments demonstrate that Infi-Med achieves state-of-the-art (SOTA) performance in general medical reasoning while maintaining rapid adaptability to clinical scenarios. The framework establishes a solid foundation for deploying MLLMs in real-world healthcare settings by balancing model effectiveness with operational constraints.

In biomedical imaging analysis, the dichotomy between 2D and 3D data presents a significant challenge. While 3D volumes offer superior real-world applicability, they are less available for each modality and not easy to train in large scale, whereas 2D samples are abundant but less comprehensive. This paper introduces the Cross-D Conv operation, a novel approach that bridges the dimensional gap by learning the phase shifting in the Fourier domain. Our method enables seamless weight transfer between 2D and 3D convolution operations, effectively facilitating cross-dimensional learning. The proposed architecture leverages the abundance of 2D training data to enhance 3D model performance, offering a practical solution to the multimodal data scarcity challenge in 3D medical model pretraining. Experimental validation on the RadImagenet (2D) and multimodal (3D) sets demonstrates that our approach achieves comparable or superior performance in feature quality assessment comparable to conventional methods. The enhanced convolution operation presents new opportunities for developing efficient classification and segmentation models in medical imaging. This work represents an advancement in cross-dimensional and multi-modal medical image analysis, offering a robust framework for utilizing 2D priors in 3D model pretraining or vice versa while maintaining computational efficiency.

Understanding objects through multiple sensory modalities is fundamental to human perception, enabling cross-sensory integration and richer comprehension. For AI and robotic systems to replicate this ability, access to diverse, high-quality multi-sensory data is critical. Existing datasets are often limited by their focus on controlled environments, simulated objects, or restricted modality pairings. We introduce X-Capture, an open-source, portable, and cost-effective device for real-world multi-sensory data collection, capable of capturing correlated RGBD images, tactile readings, and impact audio. With a build cost under $1,000, X-Capture democratizes the creation of multi-sensory datasets, requiring only consumer-grade tools for assembly. Using X-Capture, we curate a sample dataset of 3,000 total points on 500 everyday objects from diverse, real-world environments, offering both richness and variety. Our experiments demonstrate the value of both the quantity and the sensory breadth of our data for both pretraining and fine-tuning multi-modal representations for object-centric tasks such as cross-sensory retrieval and reconstruction. X-Capture lays the groundwork for advancing human-like sensory representations in AI, emphasizing scalability, accessibility, and real-world applicability.

While many BERT-based cross-modal pre-trained models produce excellent results on downstream understanding tasks like image-text retrieval and VQA, they cannot be applied to generation tasks directly. In this paper, we propose XGPT, a new method of Cross-modal Generative Pre-Training for Image Captioning that is designed to pre-train text-to-image caption generators through three novel generation tasks, including Image-conditioned Masked Language Modeling (IMLM), Image-conditioned Denoising Autoencoding (IDA), and Text-conditioned Image Feature Generation (TIFG). As a result, the pre-trained XGPT can be fine-tuned without any task-specific architecture modifications to create state-of-the-art models for image captioning. Experiments show that XGPT obtains new state-of-the-art results on the benchmark datasets, including COCO Captions and Flickr30k Captions. We also use XGPT to generate new image captions as data augmentation for the image retrieval task and achieve significant improvement on all recall metrics.

Pre-trained models for programming languages have recently demonstrated great success on code intelligence. To support both code-related understanding and generation tasks, recent works attempt to pre-train unified encoder-decoder models. However, such encoder-decoder framework is sub-optimal for auto-regressive tasks, especially code completion that requires a decoder-only manner for efficient inference. In this paper, we present UniXcoder, a unified cross-modal pre-trained model for programming language. The model utilizes mask attention matrices with prefix adapters to control the behavior of the model and leverages cross-modal contents like AST and code comment to enhance code representation. To encode AST that is represented as a tree in parallel, we propose a one-to-one mapping method to transform AST in a sequence structure that retains all structural information from the tree. Furthermore, we propose to utilize multi-modal contents to learn representation of code fragment with contrastive learning, and then align representations among programming languages using a cross-modal generation task. We evaluate UniXcoder on five code-related tasks over nine datasets. To further evaluate the performance of code fragment representation, we also construct a dataset for a new task, called zero-shot code-to-code search. Results show that our model achieves state-of-the-art performance on most tasks and analysis reveals that comment and AST can both enhance UniXcoder.

Vision-Language Pre-training (VLP) models have shown remarkable performance on various downstream tasks. Their success heavily relies on the scale of pre-trained cross-modal datasets. However, the lack of large-scale datasets and benchmarks in Chinese hinders the development of Chinese VLP models and broader multilingual applications. In this work, we release a large-scale Chinese cross-modal dataset named Wukong, which contains 100 million Chinese image-text pairs collected from the web. Wukong aims to benchmark different multi-modal pre-training methods to facilitate the VLP research and community development. Furthermore, we release a group of models pre-trained with various image encoders (ViT-B/ViT-L/SwinT) and also apply advanced pre-training techniques into VLP such as locked-image text tuning, token-wise similarity in contrastive learning, and reduced-token interaction. Extensive experiments and a benchmarking of different downstream tasks including a new largest human-verified image-text test dataset are also provided. Experiments show that Wukong can serve as a promising Chinese pre-training dataset and benchmark for different cross-modal learning methods. For the zero-shot image classification task on 10 datasets, Wukong_{ViT-L} achieves an average accuracy of 73.03%. For the image-text retrieval task, it achieves a mean recall of 71.6% on AIC-ICC which is 12.9% higher than WenLan 2.0. Also, our Wukong models are benchmarked on downstream tasks with other variants on multiple datasets, e.g., Flickr8K-CN, Flickr-30K-CN, COCO-CN, et al. More information can be referred to: https://wukong-dataset.github.io/wukong-dataset/.

We present the Modality Integration Rate (MIR), an effective, robust, and generalized metric to indicate the multi-modal pre-training quality of Large Vision Language Models (LVLMs). Large-scale pre-training plays a critical role in building capable LVLMs, while evaluating its training quality without the costly supervised fine-tuning stage is under-explored. Loss, perplexity, and in-context evaluation results are commonly used pre-training metrics for Large Language Models (LLMs), while we observed that these metrics are less indicative when aligning a well-trained LLM with a new modality. Due to the lack of proper metrics, the research of LVLMs in the critical pre-training stage is hindered greatly, including the training data choice, efficient module design, etc. In this paper, we propose evaluating the pre-training quality from the inter-modal distribution distance perspective and present MIR, the Modality Integration Rate, which is 1) Effective to represent the pre-training quality and show a positive relation with the benchmark performance after supervised fine-tuning. 2) Robust toward different training/evaluation data. 3) Generalize across training configurations and architecture choices. We conduct a series of pre-training experiments to explore the effectiveness of MIR and observe satisfactory results that MIR is indicative about training data selection, training strategy schedule, and model architecture design to get better pre-training results. We hope MIR could be a helpful metric for building capable LVLMs and inspire the following research about modality alignment in different areas. Our code is at: https://github.com/shikiw/Modality-Integration-Rate.

Existed pre-training methods either focus on single-modal tasks or multi-modal tasks, and cannot effectively adapt to each other. They can only utilize single-modal data (i.e. text or image) or limited multi-modal data (i.e. image-text pairs). In this work, we propose a unified-modal pre-training architecture, namely UNIMO, which can effectively adapt to both single-modal and multi-modal understanding and generation tasks. Large scale of free text corpus and image collections can be utilized to improve the capability of visual and textual understanding, and cross-modal contrastive learning (CMCL) is leveraged to align the textual and visual information into a unified semantic space over a corpus of image-text pairs. As the non-paired single-modal data is very rich, our model can utilize much larger scale of data to learn more generalizable representations. Moreover, the textual knowledge and visual knowledge can enhance each other in the unified semantic space. The experimental results show that UNIMO significantly improves the performance of several single-modal and multi-modal downstream tasks. Our code and pre-trained models are public at the UNIMO project page https://unimo-ptm.github.io/

Cross-lingual Cross-modal Retrieval (CCR) is an essential task in web search, which aims to break the barriers between modality and language simultaneously and achieves image-text retrieval in the multi-lingual scenario with a single model. In recent years, excellent progress has been made based on cross-lingual cross-modal pre-training; particularly, the methods based on contrastive learning on large-scale data have significantly improved retrieval tasks. However, these methods directly follow the existing pre-training methods in the cross-lingual or cross-modal domain, leading to two problems of inconsistency in CCR: The methods with cross-lingual style suffer from the intra-modal error propagation, resulting in inconsistent recall performance across languages in the whole dataset. The methods with cross-modal style suffer from the inter-modal optimization direction bias, resulting in inconsistent rank across languages within each instance, which cannot be reflected by Recall@K. To solve these problems, we propose a simple but effective 1-to-K contrastive learning method, which treats each language equally and eliminates error propagation and optimization bias. In addition, we propose a new evaluation metric, Mean Rank Variance (MRV), to reflect the rank inconsistency across languages within each instance. Extensive experiments on four CCR datasets show that our method improves both recall rates and MRV with smaller-scale pre-trained data, achieving the new state-of-art.

Multi-modal pre-training models have been intensively explored to bridge vision and language in recent years. However, most of them explicitly model the cross-modal interaction between image-text pairs, by assuming that there exists strong semantic correlation between the text and image modalities. Since this strong assumption is often invalid in real-world scenarios, we choose to implicitly model the cross-modal correlation for large-scale multi-modal pre-training, which is the focus of the Chinese project `WenLan' led by our team. Specifically, with the weak correlation assumption over image-text pairs, we propose a two-tower pre-training model called BriVL within the cross-modal contrastive learning framework. Unlike OpenAI CLIP that adopts a simple contrastive learning method, we devise a more advanced algorithm by adapting the latest method MoCo into the cross-modal scenario. By building a large queue-based dictionary, our BriVL can incorporate more negative samples in limited GPU resources. We further construct a large Chinese multi-source image-text dataset called RUC-CAS-WenLan for pre-training our BriVL model. Extensive experiments demonstrate that the pre-trained BriVL model outperforms both UNITER and OpenAI CLIP on various downstream tasks.

Cross-modal pre-training has shown impressive performance on a wide range of downstream tasks, benefiting from massive image-text pairs collected from the Internet. In practice, online data are growing constantly, highlighting the importance of the ability of pre-trained model to learn from data that is continuously growing. Existing works on cross-modal pre-training mainly focus on training a network with fixed architecture. However, it is impractical to limit the model capacity when considering the continuously growing nature of pre-training data in real-world applications. On the other hand, it is important to utilize the knowledge in the current model to obtain efficient training and better performance. To address the above issues, in this paper, we propose GrowCLIP, a data-driven automatic model growing algorithm for contrastive language-image pre-training with continuous image-text pairs as input. Specially, we adopt a dynamic growth space and seek out the optimal architecture at each growth step to adapt to online learning scenarios. And the shared encoder is proposed in our growth space to enhance the degree of cross-modal fusion. Besides, we explore the effect of growth in different dimensions, which could provide future references for the design of cross-modal model architecture. Finally, we employ parameter inheriting with momentum (PIM) to maintain the previous knowledge and address the issue of the local minimum dilemma. Compared with the existing methods, GrowCLIP improves 2.3% average top-1 accuracy on zero-shot image classification of 9 downstream tasks. As for zero-shot image retrieval, GrowCLIP can improve 1.2% for top-1 image-to-text recall on Flickr30K dataset.

Molecular knowledge resides within three different modalities of information sources: molecular structures, biomedical documents, and knowledge bases. Effective incorporation of molecular knowledge from these modalities holds paramount significance in facilitating biomedical research. However, existing multimodal molecular foundation models exhibit limitations in capturing intricate connections between molecular structures and texts, and more importantly, none of them attempt to leverage a wealth of molecular expertise derived from knowledge graphs. In this study, we introduce MolFM, a multimodal molecular foundation model designed to facilitate joint representation learning from molecular structures, biomedical texts, and knowledge graphs. We propose cross-modal attention between atoms of molecular structures, neighbors of molecule entities and semantically related texts to facilitate cross-modal comprehension. We provide theoretical analysis that our cross-modal pre-training captures local and global molecular knowledge by minimizing the distance in the feature space between different modalities of the same molecule, as well as molecules sharing similar structures or functions. MolFM achieves state-of-the-art performance on various downstream tasks. On cross-modal retrieval, MolFM outperforms existing models with 12.13% and 5.04% absolute gains under the zero-shot and fine-tuning settings, respectively. Furthermore, qualitative analysis showcases MolFM's implicit ability to provide grounding from molecular substructures and knowledge graphs. Code and models are available on https://github.com/BioFM/OpenBioMed.

Large Multimodal Models (LMMs) encode rich factual knowledge via cross-modal pre-training, yet their static representations struggle to maintain an accurate understanding of time-sensitive factual knowledge. Existing benchmarks remain constrained by static designs, inadequately evaluating LMMs' ability to understand time-sensitive knowledge. To address this gap, we propose MINED, a comprehensive benchmark that evaluates temporal awareness along 6 key dimensions and 11 challenging tasks: cognition, awareness, trustworthiness, understanding, reasoning, and robustness. MINED is constructed from Wikipedia by two professional annotators, containing 2,104 time-sensitive knowledge samples spanning six knowledge types. Evaluating 15 widely used LMMs on MINED shows that Gemini-2.5-Pro achieves the highest average CEM score of 63.07, while most open-source LMMs still lack time understanding ability. Meanwhile, LMMs perform best on organization knowledge, whereas their performance is weakest on sport. To address these challenges, we investigate the feasibility of updating time-sensitive knowledge in LMMs through knowledge editing methods and observe that LMMs can effectively update knowledge via knowledge editing methods in single editing scenarios.

Training a 3D scene understanding model requires complicated human annotations, which are laborious to collect and result in a model only encoding close-set object semantics. In contrast, vision-language pre-training models (e.g., CLIP) have shown remarkable open-world reasoning properties. To this end, we propose directly transferring CLIP's feature space to 3D scene understanding model without any form of supervision. We first modify CLIP's input and forwarding process so that it can be adapted to extract dense pixel features for 3D scene contents. We then project multi-view image features to the point cloud and train a 3D scene understanding model with feature distillation. Without any annotations or additional training, our model achieves promising annotation-free semantic segmentation results on open-vocabulary semantics and long-tailed concepts. Besides, serving as a cross-modal pre-training framework, our method can be used to improve data efficiency during fine-tuning. Our model outperforms previous SOTA methods in various zero-shot and data-efficient learning benchmarks. Most importantly, our model successfully inherits CLIP's rich-structured knowledge, allowing 3D scene understanding models to recognize not only object concepts but also open-world semantics.

Large Vision Language Models (LVLMs) have demonstrated impressive zero-shot capabilities in various vision-language dialogue scenarios. However, the absence of fine-grained visual object detection hinders the model from understanding the details of images, leading to irreparable visual hallucinations and factual errors. In this paper, we propose Lyrics, a novel multi-modal pre-training and instruction fine-tuning paradigm that bootstraps vision-language alignment from fine-grained cross-modal collaboration. Building on the foundation of BLIP-2, Lyrics infuses local visual features extracted from a visual refiner that includes image tagging, object detection and semantic segmentation modules into the Querying Transformer, while on the text side, the language inputs equip the boundary boxes and tags derived from the visual refiner. We further introduce a two-stage training scheme, in which the pre-training stage bridges the modality gap through explicit and comprehensive vision-language alignment targets. During the instruction fine-tuning stage, we introduce semantic-aware visual feature extraction, a crucial method that enables the model to extract informative features from concrete visual objects. Our approach achieves strong performance on 13 held-out datasets across various vision-language tasks, and demonstrates promising multi-modal understanding and detailed depiction capabilities in real dialogue scenarios.

Self-supervised learning has greatly facilitated medical image analysis by suppressing the training data requirement for real-world applications. Current paradigms predominantly rely on self-supervision within uni-modal image data, thereby neglecting the inter-modal correlations essential for effective learning of cross-modal image representations. This limitation is particularly significant for naturally grouped multi-modal data, e.g., multi-parametric MRI scans for a patient undergoing various functional imaging protocols in the same study. To bridge this gap, we conduct a novel multi-modal image pre-training with three proxy tasks to facilitate the learning of cross-modality representations and correlations using multi-modal brain MRI scans (over 2.4 million images in 16,022 scans of 3,755 patients), i.e., cross-modal image reconstruction, modality-aware contrastive learning, and modality template distillation. To demonstrate the generalizability of our pre-trained model, we conduct extensive experiments on various benchmarks with ten downstream tasks. The superior performance of our method is reported in comparison to state-of-the-art pre-training methods, with Dice Score improvement of 0.28\%-14.47\% across six segmentation benchmarks and a consistent accuracy boost of 0.65\%-18.07\% in four individual image classification tasks.

Improving text representation has attracted much attention to achieve expressive text-to-speech (TTS). However, existing works only implicitly learn the prosody with masked token reconstruction tasks, which leads to low training efficiency and difficulty in prosody modeling. We propose CLAPSpeech, a cross-modal contrastive pre-training framework that explicitly learns the prosody variance of the same text token under different contexts. Specifically, 1) We encourage the model to connect the text context with its corresponding prosody pattern in the joint multi-modal space with the elaborate design of the encoder inputs and contrastive loss; 2) We introduce a multi-scale pre-training pipeline to capture prosody patterns in multiple levels. We show how to incorporate CLAPSpeech into existing TTS models for better prosody. Experiments on three datasets not only show that CLAPSpeech could improve the prosody prediction for existing TTS methods, but also demonstrate its generalization ability to adapt to multiple languages and multi-speaker TTS. We also deeply analyze the principle behind the performance of CLAPSpeech. Ablation studies demonstrate the necessity of each component in our method. Source code and audio samples are available at https://clapspeech.github.io.

Recent studies have demonstrated the efficiency of generative pretraining for English natural language understanding. In this work, we extend this approach to multiple languages and show the effectiveness of cross-lingual pretraining. We propose two methods to learn cross-lingual language models (XLMs): one unsupervised that only relies on monolingual data, and one supervised that leverages parallel data with a new cross-lingual language model objective. We obtain state-of-the-art results on cross-lingual classification, unsupervised and supervised machine translation. On XNLI, our approach pushes the state of the art by an absolute gain of 4.9% accuracy. On unsupervised machine translation, we obtain 34.3 BLEU on WMT'16 German-English, improving the previous state of the art by more than 9 BLEU. On supervised machine translation, we obtain a new state of the art of 38.5 BLEU on WMT'16 Romanian-English, outperforming the previous best approach by more than 4 BLEU. Our code and pretrained models will be made publicly available.

Motivated by the success of T5 (Text-To-Text Transfer Transformer) in pre-trained natural language processing models, we propose a unified-modal SpeechT5 framework that explores the encoder-decoder pre-training for self-supervised speech/text representation learning. The SpeechT5 framework consists of a shared encoder-decoder network and six modal-specific (speech/text) pre/post-nets. After preprocessing the input speech/text through the pre-nets, the shared encoder-decoder network models the sequence-to-sequence transformation, and then the post-nets generate the output in the speech/text modality based on the output of the decoder. Leveraging large-scale unlabeled speech and text data, we pre-train SpeechT5 to learn a unified-modal representation, hoping to improve the modeling capability for both speech and text. To align the textual and speech information into this unified semantic space, we propose a cross-modal vector quantization approach that randomly mixes up speech/text states with latent units as the interface between encoder and decoder. Extensive evaluations show the superiority of the proposed SpeechT5 framework on a wide variety of spoken language processing tasks, including automatic speech recognition, speech synthesis, speech translation, voice conversion, speech enhancement, and speaker identification. We release our code and model at https://github.com/microsoft/SpeechT5.

Recent work has demonstrated the effectiveness of cross-lingual language model pretraining for cross-lingual understanding. In this study, we present the results of two larger multilingual masked language models, with 3.5B and 10.7B parameters. Our two new models dubbed XLM-R XL and XLM-R XXL outperform XLM-R by 1.8% and 2.4% average accuracy on XNLI. Our model also outperforms the RoBERTa-Large model on several English tasks of the GLUE benchmark by 0.3% on average while handling 99 more languages. This suggests pretrained models with larger capacity may obtain both strong performance on high-resource languages while greatly improving low-resource languages. We make our code and models publicly available.

In this technical report, we present Zyda-2: a five trillion token dataset for language model pretraining. Zyda-2 was used to train our Zamba2 series of models which are state-of-the-art for their weight class. We build Zyda-2 by collating high-quality open-source tokens such as FineWeb and DCLM, then distilling them to the highest-quality subset via cross-deduplication and model-based quality filtering. Zyda-2 is released under a permissive open license, and is available at https://huggingface.co/datasets/Zyphra/Zyda-2

Recent studies have indicated that vision models pre-trained on images can serve as time series foundation models (TSFMs) by reformulating time series forecasting (TSF) as image reconstruction. However, effective cross-modal transfer from vision to time series remains challenging due to three discrepancies: (1) the data-modality gap between structured, bounded image data and unbounded, heterogeneous time series; (2) the multivariate-forecasting gap between fixed RGB-three-channel vision models and time series with arbitrary numbers of variates; and (3) the probabilistic-forecasting gap between the deterministic outputs of vision models and the requirement for uncertainty-aware probabilistic predictions. To bridge these gaps, we propose VisonTS++, a TSFM based on continual pre-training of a vision model on large-scale time series. Our approach introduces three key innovations: (1) vision-model-based filtering to identify high-quality sequences to stabilize pre-training and mitigate modality gap; (2) colorized multivariate conversion, encoding multivariate series as multi-subfigure RGB images to enhance cross-variate modeling; (3) multi-quantile forecasting, using parallel reconstruction heads to generate quantile forecasts without parametric assumptions. Experiments show that VisionTS++ achieves state-of-the-art performance in both in-distribution and out-of-distribution forecasting, outperforming specialized TSFMs by 6%-44% in MSE reduction and ranking first in GIFT-Eval benchmark which comprises 23 datasets across 7 domains. Our work demonstrates that with appropriate adaptation, vision models can effectively generalize to TSF, thus advancing the pursuit of universal TSFMs. Code is available at https://github.com/HALF111/VisionTSpp.

We introduce CLaMP: Contrastive Language-Music Pre-training, which learns cross-modal representations between natural language and symbolic music using a music encoder and a text encoder trained jointly with a contrastive loss. To pre-train CLaMP, we collected a large dataset of 1.4 million music-text pairs. It employed text dropout as a data augmentation technique and bar patching to efficiently represent music data which reduces sequence length to less than 10%. In addition, we developed a masked music model pre-training objective to enhance the music encoder's comprehension of musical context and structure. CLaMP integrates textual information to enable semantic search and zero-shot classification for symbolic music, surpassing the capabilities of previous models. To support the evaluation of semantic search and music classification, we publicly release WikiMusicText (WikiMT), a dataset of 1010 lead sheets in ABC notation, each accompanied by a title, artist, genre, and description. In comparison to state-of-the-art models that require fine-tuning, zero-shot CLaMP demonstrated comparable or superior performance on score-oriented datasets.

The scale diversity of point cloud data presents significant challenges in developing unified representation learning techniques for 3D vision. Currently, there are few unified 3D models, and no existing pre-training method is equally effective for both object- and scene-level point clouds. In this paper, we introduce UniPre3D, the first unified pre-training method that can be seamlessly applied to point clouds of any scale and 3D models of any architecture. Our approach predicts Gaussian primitives as the pre-training task and employs differentiable Gaussian splatting to render images, enabling precise pixel-level supervision and end-to-end optimization. To further regulate the complexity of the pre-training task and direct the model's focus toward geometric structures, we integrate 2D features from pre-trained image models to incorporate well-established texture knowledge. We validate the universal effectiveness of our proposed method through extensive experiments across a variety of object- and scene-level tasks, using diverse point cloud models as backbones. Code is available at https://github.com/wangzy22/UniPre3D.

Recently, speech-text pre-training methods have shown remarkable success in many speech and natural language processing tasks. However, most previous pre-trained models are usually tailored for one or two specific tasks, but fail to conquer a wide range of speech-text tasks. In addition, existing speech-text pre-training methods fail to explore the contextual information within a dialogue to enrich utterance representations. In this paper, we propose Speech-text dialog Pre-training for spoken dialog understanding with ExpliCiT cRoss-Modal Alignment (SPECTRA), which is the first-ever speech-text dialog pre-training model. Concretely, to consider the temporality of speech modality, we design a novel temporal position prediction task to capture the speech-text alignment. This pre-training task aims to predict the start and end time of each textual word in the corresponding speech waveform. In addition, to learn the characteristics of spoken dialogs, we generalize a response selection task from textual dialog pre-training to speech-text dialog pre-training scenarios. Experimental results on four different downstream speech-text tasks demonstrate the superiority of SPECTRA in learning speech-text alignment and multi-turn dialog context.

Contrastive language-image pre-training (CLIP) has demonstrated remarkable zero-shot classification ability, namely image classification using novel text labels. Existing works have attempted to enhance CLIP by fine-tuning on downstream tasks, but these have inadvertently led to performance degradation on unseen classes, thus harming zero-shot generalization. This paper aims to address this challenge by leveraging readily available image-text pairs from an external dataset for cross-modal guidance during inference. To this end, we propose X-MoRe, a novel inference method comprising two key steps: (1) cross-modal retrieval and (2) modal-confidence-based ensemble. Given a query image, we harness the power of CLIP's cross-modal representations to retrieve relevant textual information from an external image-text pair dataset. Then, we assign higher weights to the more reliable modality between the original query image and retrieved text, contributing to the final prediction. X-MoRe demonstrates robust performance across a diverse set of tasks without the need for additional training, showcasing the effectiveness of utilizing cross-modal features to maximize CLIP's zero-shot ability.

This paper considers self-supervised cross-modal coordination as a strategy enabling utilization of multiple modalities and large volumes of unlabeled plankton data to build models for plankton recognition. Automated imaging instruments facilitate the continuous collection of plankton image data on a large scale. Current methods for automatic plankton image recognition rely primarily on supervised approaches, which require labeled training sets that are labor-intensive to collect. On the other hand, some modern plankton imaging instruments complement image information with optical measurement data, such as scatter and fluorescence profiles, which currently are not widely utilized in plankton recognition. In this work, we explore the possibility of using such measurement data to guide the learning process without requiring manual labeling. Inspired by the concepts behind Contrastive Language-Image Pre-training, we train encoders for both modalities using only binary supervisory information indicating whether a given image and profile originate from the same particle or from different particles. For plankton recognition, we employ a small labeled gallery of known plankton species combined with a k-NN classifier. This approach yields a recognition model that is inherently multimodal, i.e., capable of utilizing information extracted from both image and profile data. We demonstrate that the proposed method achieves high recognition accuracy while requiring only a minimal number of labeled images. Furthermore, we show that the approach outperforms an image-only self-supervised baseline. Code available at https://github.com/Jookare/cross-modal-plankton.

The significance of informative and robust point representations has been widely acknowledged for 3D scene understanding. Despite existing self-supervised pre-training counterparts demonstrating promising performance, the model collapse and structural information deficiency remain prevalent due to insufficient point discrimination difficulty, yielding unreliable expressions and suboptimal performance. In this paper, we present GaussianCross, a novel cross-modal self-supervised 3D representation learning architecture integrating feed-forward 3D Gaussian Splatting (3DGS) techniques to address current challenges. GaussianCross seamlessly converts scale-inconsistent 3D point clouds into a unified cuboid-normalized Gaussian representation without missing details, enabling stable and generalizable pre-training. Subsequently, a tri-attribute adaptive distillation splatting module is incorporated to construct a 3D feature field, facilitating synergetic feature capturing of appearance, geometry, and semantic cues to maintain cross-modal consistency. To validate GaussianCross, we perform extensive evaluations on various benchmarks, including ScanNet, ScanNet200, and S3DIS. In particular, GaussianCross shows a prominent parameter and data efficiency, achieving superior performance through linear probing (<0.1% parameters) and limited data training (1% of scenes) compared to state-of-the-art methods. Furthermore, GaussianCross demonstrates strong generalization capabilities, improving the full fine-tuning accuracy by 9.3% mIoU and 6.1% AP_{50} on ScanNet200 semantic and instance segmentation tasks, respectively, supporting the effectiveness of our approach. The code, weights, and visualizations are publicly available at https://rayyoh.github.io/GaussianCross/{https://rayyoh.github.io/GaussianCross/}.

Recently, semantic segmentation models trained with image-level text supervision have shown promising results in challenging open-world scenarios. However, these models still face difficulties in learning fine-grained semantic alignment at the pixel level and predicting accurate object masks. To address this issue, we propose MixReorg, a novel and straightforward pre-training paradigm for semantic segmentation that enhances a model's ability to reorganize patches mixed across images, exploring both local visual relevance and global semantic coherence. Our approach involves generating fine-grained patch-text pairs data by mixing image patches while preserving the correspondence between patches and text. The model is then trained to minimize the segmentation loss of the mixed images and the two contrastive losses of the original and restored features. With MixReorg as a mask learner, conventional text-supervised semantic segmentation models can achieve highly generalizable pixel-semantic alignment ability, which is crucial for open-world segmentation. After training with large-scale image-text data, MixReorg models can be applied directly to segment visual objects of arbitrary categories, without the need for further fine-tuning. Our proposed framework demonstrates strong performance on popular zero-shot semantic segmentation benchmarks, outperforming GroupViT by significant margins of 5.0%, 6.2%, 2.5%, and 3.4% mIoU on PASCAL VOC2012, PASCAL Context, MS COCO, and ADE20K, respectively.

Image matching, which aims to identify corresponding pixel locations between images, is crucial in a wide range of scientific disciplines, aiding in image registration, fusion, and analysis. In recent years, deep learning-based image matching algorithms have dramatically outperformed humans in rapidly and accurately finding large amounts of correspondences. However, when dealing with images captured under different imaging modalities that result in significant appearance changes, the performance of these algorithms often deteriorates due to the scarcity of annotated cross-modal training data. This limitation hinders applications in various fields that rely on multiple image modalities to obtain complementary information. To address this challenge, we propose a large-scale pre-training framework that utilizes synthetic cross-modal training signals, incorporating diverse data from various sources, to train models to recognize and match fundamental structures across images. This capability is transferable to real-world, unseen cross-modality image matching tasks. Our key finding is that the matching model trained with our framework achieves remarkable generalizability across more than eight unseen cross-modality registration tasks using the same network weight, substantially outperforming existing methods, whether designed for generalization or tailored for specific tasks. This advancement significantly enhances the applicability of image matching technologies across various scientific disciplines and paves the way for new applications in multi-modality human and artificial intelligence analysis and beyond.

Vision-language pre-training (VLP) on large-scale datasets has shown premier performance on various downstream tasks. In contrast to plenty of available benchmarks with English corpus, large-scale pre-training datasets and downstream datasets with Chinese corpus remain largely unexplored. In this work, we build a large-scale high-quality Chinese Cross-Modal Benchmark named CCMB for the research community, which contains the currently largest public pre-training dataset Zero and five human-annotated fine-tuning datasets for downstream tasks. Zero contains 250 million images paired with 750 million text descriptions, plus two of the five fine-tuning datasets are also currently the largest ones for Chinese cross-modal downstream tasks. Along with the CCMB, we also develop a VLP framework named R2D2, applying a pre-Ranking + Ranking strategy to learn powerful vision-language representations and a two-way distillation method (i.e., target-guided Distillation and feature-guided Distillation) to further enhance the learning capability. With the Zero and the R2D2 VLP framework, we achieve state-of-the-art performance on twelve downstream datasets from five broad categories of tasks including image-text retrieval, image-text matching, image caption, text-to-image generation, and zero-shot image classification. The datasets, models, and codes are available at https://github.com/yuxie11/R2D2

An important challenge in vision-based action recognition is the embedding of spatiotemporal features with two or more heterogeneous modalities into a single feature. In this study, we propose a new 3D deformable transformer for action recognition with adaptive spatiotemporal receptive fields and a cross-modal learning scheme. The 3D deformable transformer consists of three attention modules: 3D deformability, local joint stride, and temporal stride attention. The two cross-modal tokens are input into the 3D deformable attention module to create a cross-attention token with a reflected spatiotemporal correlation. Local joint stride attention is applied to spatially combine attention and pose tokens. Temporal stride attention temporally reduces the number of input tokens in the attention module and supports temporal expression learning without the simultaneous use of all tokens. The deformable transformer iterates L-times and combines the last cross-modal token for classification. The proposed 3D deformable transformer was tested on the NTU60, NTU120, FineGYM, and PennAction datasets, and showed results better than or similar to pre-trained state-of-the-art methods even without a pre-training process. In addition, by visualizing important joints and correlations during action recognition through spatial joint and temporal stride attention, the possibility of achieving an explainable potential for action recognition is presented.

Recent advancements in biological research leverage the integration of molecules, proteins, and natural language to enhance drug discovery. However, current models exhibit several limitations, such as the generation of invalid molecular SMILES, underutilization of contextual information, and equal treatment of structured and unstructured knowledge. To address these issues, we propose BioT5, a comprehensive pre-training framework that enriches cross-modal integration in biology with chemical knowledge and natural language associations. BioT5 utilizes SELFIES for 100% robust molecular representations and extracts knowledge from the surrounding context of bio-entities in unstructured biological literature. Furthermore, BioT5 distinguishes between structured and unstructured knowledge, leading to more effective utilization of information. After fine-tuning, BioT5 shows superior performance across a wide range of tasks, demonstrating its strong capability of capturing underlying relations and properties of bio-entities. Our code is available at https://github.com/QizhiPei/BioT5{Github}.

Contrastive Language--Image Pre-training (CLIP) has manifested remarkable improvements in zero-shot classification and cross-modal vision-language tasks. Yet, from a geometrical point of view, the CLIP embedding space has been found to have a pronounced modality gap. This gap renders the embedding space overly sparse and disconnected, with different modalities being densely distributed in distinct subregions of the hypersphere. In this work, we aim at answering two main questions: 1. Does sharing the parameter space between the multi-modal encoders reduce the modality gap? 2. Can the gap be mitigated by pushing apart the uni-modal embeddings via intra-modality separation? We design AlignCLIP, in order to answer these questions and show that answers to both questions are positive. Through extensive experiments, we show that AlignCLIP achieves noticeable enhancements in the cross-modal alignment of the embeddings, and thereby, reduces the modality gap, while maintaining the performance across several downstream evaluations, such as zero-shot image classification, zero-shot multi-modal retrieval and zero-shot semantic text similarity.

Vision-language pre-training and instruction tuning have demonstrated general-purpose capabilities in 2D visual reasoning tasks by aligning visual encoders with state-of-the-art large language models (LLMs). In this paper, we introduce a simple, yet effective, cross-modality framework built atop frozen LLMs that allows the integration of various modalities without extensive modality-specific customization. To facilitate instruction-modality fine-tuning, we collect high-quality instruction tuning data in an automatic and scalable manner, composed of 24K QA samples for audio and 250K QA samples for 3D. Leveraging instruction-aware representations, our model performs comparably with leading-edge counterparts without the need of extensive modality-specific pre-training or customization. Furthermore, our approach demonstrates cross-modal reasoning abilities across two or more input modalities, despite each modality projection being trained individually. To study the model's cross-modal abilities, we contribute a novel Discriminative Cross-modal Reasoning (DisCRn) evaluation task, comprising 9K audio-video QA samples and 28K image-3D QA samples that require the model to reason discriminatively across disparate input modalities.

During the preceding biennium, vision-language pre-training has achieved noteworthy success on several downstream tasks. Nevertheless, acquiring high-quality image-text pairs, where the pairs are entirely exclusive of each other, remains a challenging task, and noise exists in the commonly used datasets. To address this issue, we propose SoftCLIP, a novel approach that relaxes the strict one-to-one constraint and achieves a soft cross-modal alignment by introducing a softened target, which is generated from the fine-grained intra-modal self-similarity. The intra-modal guidance is indicative to enable two pairs have some local similarities and model many-to-many relationships between the two modalities. Besides, since the positive still dominates in the softened target distribution, we disentangle the negatives in the distribution to further boost the relation alignment with the negatives in the cross-modal learning. Extensive experiments demonstrate the effectiveness of SoftCLIP. In particular, on ImageNet zero-shot classification task, using CC3M/CC12M as pre-training dataset, SoftCLIP brings a top-1 accuracy improvement of 6.8%/7.2% over the CLIP baseline.

Pre-training of text and layout has proved effective in a variety of visually-rich document understanding tasks due to its effective model architecture and the advantage of large-scale unlabeled scanned/digital-born documents. We propose LayoutLMv2 architecture with new pre-training tasks to model the interaction among text, layout, and image in a single multi-modal framework. Specifically, with a two-stream multi-modal Transformer encoder, LayoutLMv2 uses not only the existing masked visual-language modeling task but also the new text-image alignment and text-image matching tasks, which make it better capture the cross-modality interaction in the pre-training stage. Meanwhile, it also integrates a spatial-aware self-attention mechanism into the Transformer architecture so that the model can fully understand the relative positional relationship among different text blocks. Experiment results show that LayoutLMv2 outperforms LayoutLM by a large margin and achieves new state-of-the-art results on a wide variety of downstream visually-rich document understanding tasks, including FUNSD (0.7895 to 0.8420), CORD (0.9493 to 0.9601), SROIE (0.9524 to 0.9781), Kleister-NDA (0.8340 to 0.8520), RVL-CDIP (0.9443 to 0.9564), and DocVQA (0.7295 to 0.8672). We made our model and code publicly available at https://aka.ms/layoutlmv2.

Vision-Language Models (VLMs) trained with contrastive loss have achieved significant advancements in various vision and language tasks. However, the global nature of contrastive loss makes VLMs focus predominantly on foreground objects, neglecting other crucial information in the image, which limits their effectiveness in downstream tasks. To address these challenges, we propose COSMOS: CrOSs-MOdality Self-distillation for vision-language pre-training that integrates a novel text-cropping strategy and cross-attention module into a self-supervised learning framework. We create global and local views of images and texts (i.e., multi-modal augmentations), which are essential for self-distillation in VLMs. We further introduce a cross-attention module, enabling COSMOS to learn comprehensive cross-modal representations optimized via a cross-modality self-distillation loss. COSMOS consistently outperforms previous strong baselines on various zero-shot downstream tasks, including retrieval, classification, and semantic segmentation. Additionally, it surpasses CLIP-based models trained on larger datasets in visual perception and contextual understanding tasks.

This paper considers contrastive training for cross-modal 0-shot transfer wherein a pre-trained model in one modality is used for representation learning in another domain using pairwise data. The learnt models in the latter domain can then be used for a diverse set of tasks in a zero-shot way, similar to ``Contrastive Language-Image Pre-training (CLIP)'' and ``Locked-image Tuning (LiT)'' that have recently gained considerable attention. Most existing works for cross-modal representation alignment (including CLIP and LiT) use the standard contrastive training objective, which employs sets of positive and negative examples to align similar and repel dissimilar training data samples. However, similarity amongst training examples has a more continuous nature, thus calling for a more `non-binary' treatment. To address this, we propose a novel loss function called Continuously Weighted Contrastive Loss (CWCL) that employs a continuous measure of similarity. With CWCL, we seek to align the embedding space of one modality with another. Owing to the continuous nature of similarity in the proposed loss function, these models outperform existing methods for 0-shot transfer across multiple models, datasets and modalities. Particularly, we consider the modality pairs of image-text and speech-text and our models achieve 5-8% (absolute) improvement over previous state-of-the-art methods in 0-shot image classification and 20-30% (absolute) improvement in 0-shot speech-to-intent classification and keyword classification.

Multilingual large language models achieve impressive cross-lingual performance despite largely monolingual pretraining. While bilingual data in pretraining corpora is widely believed to enable these abilities, details of its contributions remain unclear. We investigate this question by pretraining models from scratch under controlled conditions, comparing the standard web corpus with a monolingual-only version that removes all multilingual documents. Despite constituting only 2% of the corpus, removing bilingual data causes translation performance to drop 56% in BLEU, while behaviour on cross-lingual QA and general reasoning tasks remains stable, with training curves largely overlapping the baseline. To understand this asymmetry, we categorize bilingual data into parallel (14%), code-switching (72%), and miscellaneous documents (14%) based on the semantic relevance of content in different languages. We then conduct granular ablations by reintroducing parallel or code-switching data into the monolingual-only corpus. Our experiments reveal that parallel data almost fully restores translation performance (91% of the unfiltered baseline), whereas code-switching contributes minimally. Other cross-lingual tasks remain largely unaffected by either type. These findings reveal that translation critically depends on systematic token-level alignments from parallel data, whereas cross-lingual understanding and reasoning appear to be achievable even without bilingual data.

We present results from a large-scale experiment on pretraining encoders with non-embedding parameter counts ranging from 700M to 9.3B, their subsequent distillation into smaller models ranging from 17M-170M parameters, and their application to the Natural Language Understanding (NLU) component of a virtual assistant system. Though we train using 70% spoken-form data, our teacher models perform comparably to XLM-R and mT5 when evaluated on the written-form Cross-lingual Natural Language Inference (XNLI) corpus. We perform a second stage of pretraining on our teacher models using in-domain data from our system, improving error rates by 3.86% relative for intent classification and 7.01% relative for slot filling. We find that even a 170M-parameter model distilled from our Stage 2 teacher model has 2.88% better intent classification and 7.69% better slot filling error rates when compared to the 2.3B-parameter teacher trained only on public data (Stage 1), emphasizing the importance of in-domain data for pretraining. When evaluated offline using labeled NLU data, our 17M-parameter Stage 2 distilled model outperforms both XLM-R Base (85M params) and DistillBERT (42M params) by 4.23% to 6.14%, respectively. Finally, we present results from a full virtual assistant experimentation platform, where we find that models trained using our pretraining and distillation pipeline outperform models distilled from 85M-parameter teachers by 3.74%-4.91% on an automatic measurement of full-system user dissatisfaction.

Large language models (LLMs) are trained on text-only data that go far beyond the languages with paired speech and text data. At the same time, Dual Encoder (DE) based retrieval systems project queries and documents into the same embedding space and have demonstrated their success in retrieval and bi-text mining. To match speech and text in many languages, we propose using LLMs to initialize multi-modal DE retrieval systems. Unlike traditional methods, our system doesn't require speech data during LLM pre-training and can exploit LLM's multilingual text understanding capabilities to match speech and text in languages unseen during retrieval training. Our multi-modal LLM-based retrieval system is capable of matching speech and text in 102 languages despite only training on 21 languages. Our system outperforms previous systems trained explicitly on all 102 languages. We achieve a 10% absolute improvement in Recall@1 averaged across these languages. Additionally, our model demonstrates cross-lingual speech and text matching, which is further enhanced by readily available machine translation data.

Medical vision-and-language pre-training provides a feasible solution to extract effective vision-and-language representations from medical images and texts. However, few studies have been dedicated to this field to facilitate medical vision-and-language understanding. In this paper, we propose a self-supervised learning paradigm with multi-modal masked autoencoders (M^3AE), which learn cross-modal domain knowledge by reconstructing missing pixels and tokens from randomly masked images and texts. There are three key designs to make this simple approach work. First, considering the different information densities of vision and language, we adopt different masking ratios for the input image and text, where a considerably larger masking ratio is used for images. Second, we use visual and textual features from different layers to perform the reconstruction to deal with different levels of abstraction in visual and language. Third, we develop different designs for vision and language decoders (i.e., a Transformer for vision and a multi-layer perceptron for language). To perform a comprehensive evaluation and facilitate further research, we construct a medical vision-and-language benchmark including three tasks. Experimental results demonstrate the effectiveness of our approach, where state-of-the-art results are achieved on all downstream tasks. Besides, we conduct further analysis to better verify the effectiveness of different components of our approach and various settings of pre-training. The source code is available at~https://github.com/zhjohnchan/M3AE.

RGB-thermal (RGB-T) semantic segmentation improves the environmental perception of autonomous platforms in challenging conditions. Prevailing models employ encoders pre-trained on RGB images to extract features from both RGB and infrared inputs, and design additional modules to achieve cross-modal feature fusion. This results in limited thermal feature extraction and suboptimal cross-modal fusion, while the redundant encoders further compromises the model's real-time efficiency. To address the above issues, we propose TUNI, with an RGB-T encoder consisting of multiple stacked blocks that simultaneously perform multi-modal feature extraction and cross-modal fusion. By leveraging large-scale pre-training with RGB and pseudo-thermal data, the RGB-T encoder learns to integrate feature extraction and fusion in a unified manner. By slimming down the thermal branch, the encoder achieves a more compact architecture. Moreover, we introduce an RGB-T local module to strengthen the encoder's capacity for cross-modal local feature fusion. The RGB-T local module employs adaptive cosine similarity to selectively emphasize salient consistent and distinct local features across RGB-T modalities. Experimental results show that TUNI achieves competitive performance with state-of-the-art models on FMB, PST900 and CART, with fewer parameters and lower computational cost. Meanwhile, it achieves an inference speed of 27 FPS on a Jetson Orin NX, demonstrating its real-time capability in deployment. Codes are available at https://github.com/xiaodonguo/TUNI.

Multi-modal large language models are regarded as a crucial step towards Artificial General Intelligence (AGI) and have garnered significant interest with the emergence of ChatGPT. However, current speech-language models typically adopt the cascade paradigm, preventing inter-modal knowledge transfer. In this paper, we propose SpeechGPT, a large language model with intrinsic cross-modal conversational abilities, capable of perceiving and generating multi-model content. With discrete speech representations, we first construct SpeechInstruct, a large-scale cross-modal speech instruction dataset. Additionally, we employ a three-stage training strategy that includes modality-adaptation pre-training, cross-modal instruction fine-tuning, and chain-of-modality instruction fine-tuning. The experimental results demonstrate that SpeechGPT has an impressive capacity to follow multi-modal human instructions and highlight the potential of handling multiple modalities with one model. Demos are shown in https://0nutation.github.io/SpeechGPT.github.io/.

Large-scale vision-language pre-training has achieved promising results on downstream tasks. Existing methods highly rely on the assumption that the image-text pairs crawled from the Internet are in perfect one-to-one correspondence. However, in real scenarios, this assumption can be difficult to hold: the text description, obtained by crawling the affiliated metadata of the image, often suffers from the semantic mismatch and the mutual compatibility. To address these issues, we introduce PyramidCLIP, which constructs an input pyramid with different semantic levels for each modality, and aligns visual elements and linguistic elements in the form of hierarchy via peer-level semantics alignment and cross-level relation alignment. Furthermore, we soften the loss of negative samples (unpaired samples) so as to weaken the strict constraint during the pre-training stage, thus mitigating the risk of forcing the model to distinguish compatible negative pairs. Experiments on five downstream tasks demonstrate the effectiveness of the proposed PyramidCLIP. In particular, with the same amount of 15 million pre-training image-text pairs, PyramidCLIP exceeds CLIP on ImageNet zero-shot classification top-1 accuracy by 10.6%/13.2%/10.0% with ResNet50/ViT-B32/ViT-B16 based image encoder respectively. When scaling to larger datasets, PyramidCLIP achieves the state-of-the-art results on several downstream tasks. In particular, the results of PyramidCLIP-ResNet50 trained on 143M image-text pairs surpass that of CLIP using 400M data on ImageNet zero-shot classification task, significantly improving the data efficiency of CLIP.

Data quality is a critical driver of large language model performance, yet existing model-based selection methods focus almost exclusively on English. We introduce MuRating, a scalable framework that transfers high-quality English data-quality signals into a single rater for 17 target languages. MuRating aggregates multiple English "raters" via pairwise comparisons to learn unified document-quality scores,then projects these judgments through translation to train a multilingual evaluator on monolingual, cross-lingual, and parallel text pairs. Applied to web data, MuRating selects balanced subsets of English and multilingual content to pretrain a 1.2 B-parameter LLaMA model. Compared to strong baselines, including QuRater, AskLLM, DCLM and so on, our approach boosts average accuracy on both English benchmarks and multilingual evaluations, with especially large gains on knowledge-intensive tasks. We further analyze translation fidelity, selection biases, and underrepresentation of narrative material, outlining directions for future work.

Cross-modal alignment is one key challenge for Vision-and-Language Navigation (VLN). Most existing studies concentrate on mapping the global instruction or single sub-instruction to the corresponding trajectory. However, another critical problem of achieving fine-grained alignment at the entity level is seldom considered. To address this problem, we propose a novel Grounded Entity-Landmark Adaptive (GELA) pre-training paradigm for VLN tasks. To achieve the adaptive pre-training paradigm, we first introduce grounded entity-landmark human annotations into the Room-to-Room (R2R) dataset, named GEL-R2R. Additionally, we adopt three grounded entity-landmark adaptive pre-training objectives: 1) entity phrase prediction, 2) landmark bounding box prediction, and 3) entity-landmark semantic alignment, which explicitly supervise the learning of fine-grained cross-modal alignment between entity phrases and environment landmarks. Finally, we validate our model on two downstream benchmarks: VLN with descriptive instructions (R2R) and dialogue instructions (CVDN). The comprehensive experiments show that our GELA model achieves state-of-the-art results on both tasks, demonstrating its effectiveness and generalizability.

Video-language pre-training has advanced the performance of various downstream video-language tasks. However, most previous methods directly inherit or adapt typical image-language pre-training paradigms to video-language pre-training, thus not fully exploiting the unique characteristic of video, i.e., temporal. In this paper, we propose a Hierarchical Temporal-Aware video-language pre-training framework, HiTeA, with two novel pre-training tasks for modeling cross-modal alignment between moments and texts as well as the temporal relations of video-text pairs. Specifically, we propose a cross-modal moment exploration task to explore moments in videos, which results in detailed video moment representation. Besides, the inherent temporal relations are captured by aligning video-text pairs as a whole in different time resolutions with multi-modal temporal relation exploration task. Furthermore, we introduce the shuffling test to evaluate the temporal reliance of datasets and video-language pre-training models. We achieve state-of-the-art results on 15 well-established video-language understanding and generation tasks, especially on temporal-oriented datasets (e.g., SSv2-Template and SSv2-Label) with 8.6% and 11.1% improvement respectively. HiTeA also demonstrates strong generalization ability when directly transferred to downstream tasks in a zero-shot manner. Models and demo will be available on ModelScope.

Video-and-language pre-training has shown promising improvements on various downstream tasks. Most previous methods capture cross-modal interactions with a transformer-based multimodal encoder, not fully addressing the misalignment between unimodal video and text features. Besides, learning fine-grained visual-language alignment usually requires off-the-shelf object detectors to provide object information, which is bottlenecked by the detector's limited vocabulary and expensive computation cost. We propose Align and Prompt: an efficient and effective video-and-language pre-training framework with better cross-modal alignment. First, we introduce a video-text contrastive (VTC) loss to align unimodal video-text features at the instance level, which eases the modeling of cross-modal interactions. Then, we propose a new visually-grounded pre-training task, prompting entity modeling (PEM), which aims to learn fine-grained region-entity alignment. To achieve this, we first introduce an entity prompter module, which is trained with VTC to produce the similarity between a video crop and text prompts instantiated with entity names. The PEM task then asks the model to predict the entity pseudo-labels (i.e~normalized similarity scores) for randomly-selected video crops. The resulting pre-trained model achieves state-of-the-art performance on both text-video retrieval and videoQA, outperforming prior work by a substantial margin. Our code and pre-trained models are available at https://github.com/salesforce/ALPRO.

Large-scale pre-training methods of learning cross-modal representations on image-text pairs are becoming popular for vision-language tasks. While existing methods simply concatenate image region features and text features as input to the model to be pre-trained and use self-attention to learn image-text semantic alignments in a brute force manner, in this paper, we propose a new learning method Oscar (Object-Semantics Aligned Pre-training), which uses object tags detected in images as anchor points to significantly ease the learning of alignments. Our method is motivated by the observation that the salient objects in an image can be accurately detected, and are often mentioned in the paired text. We pre-train an Oscar model on the public corpus of 6.5 million text-image pairs, and fine-tune it on downstream tasks, creating new state-of-the-arts on six well-established vision-language understanding and generation tasks.

Large language models demonstrate reasonable multilingual abilities, despite predominantly English-centric pretraining. However, the spontaneous multilingual alignment in these models is shown to be weak, leading to unsatisfactory cross-lingual transfer and knowledge sharing. Previous works attempt to address this issue by explicitly injecting multilingual alignment information during or after pretraining. Thus for the early stage in pretraining, the alignment is weak for sharing information or knowledge across languages. In this paper, we propose PreAlign, a framework that establishes multilingual alignment prior to language model pretraining. PreAlign injects multilingual alignment by initializing the model to generate similar representations of aligned words and preserves this alignment using a code-switching strategy during pretraining. Extensive experiments in a synthetic English to English-Clone setting demonstrate that PreAlign significantly outperforms standard multilingual joint training in language modeling, zero-shot cross-lingual transfer, and cross-lingual knowledge application. Further experiments in real-world scenarios further validate PreAlign's effectiveness across various model sizes.

Vision-language representation learning largely benefits from image-text alignment through contrastive losses (e.g., InfoNCE loss). The success of this alignment strategy is attributed to its capability in maximizing the mutual information (MI) between an image and its matched text. However, simply performing cross-modal alignment (CMA) ignores data potential within each modality, which may result in degraded representations. For instance, although CMA-based models are able to map image-text pairs close together in the embedding space, they fail to ensure that similar inputs from the same modality stay close by. This problem can get even worse when the pre-training data is noisy. In this paper, we propose triple contrastive learning (TCL) for vision-language pre-training by leveraging both cross-modal and intra-modal self-supervision. Besides CMA, TCL introduces an intra-modal contrastive objective to provide complementary benefits in representation learning. To take advantage of localized and structural information from image and text input, TCL further maximizes the average MI between local regions of image/text and their global summary. To the best of our knowledge, ours is the first work that takes into account local structure information for multi-modality representation learning. Experimental evaluations show that our approach is competitive and achieves the new state of the art on various common down-stream vision-language tasks such as image-text retrieval and visual question answering.

Unsupervised large-scale vision-language pre-training has shown promising advances on various downstream tasks. Existing methods often model the cross-modal interaction either via the similarity of the global feature of each modality which misses sufficient information, or finer-grained interactions using cross/self-attention upon visual and textual tokens. However, cross/self-attention suffers from inferior efficiency in both training and inference. In this paper, we introduce a large-scale Fine-grained Interactive Language-Image Pre-training (FILIP) to achieve finer-level alignment through a cross-modal late interaction mechanism, which uses a token-wise maximum similarity between visual and textual tokens to guide the contrastive objective. FILIP successfully leverages the finer-grained expressiveness between image patches and textual words by modifying only contrastive loss, while simultaneously gaining the ability to pre-compute image and text representations offline at inference, keeping both large-scale training and inference efficient. Furthermore, we construct a new large-scale image-text pair dataset called FILIP300M for pre-training. Experiments show that FILIP achieves state-of-the-art performance on multiple downstream vision-language tasks including zero-shot image classification and image-text retrieval. The visualization on word-patch alignment further shows that FILIP can learn meaningful fine-grained features with promising localization ability.

Medical imaging plays a pivotal role in modern healthcare, with computed tomography pulmonary angiography (CTPA) being a critical tool for diagnosing pulmonary embolism and other thoracic conditions. However, the complexity of interpreting CTPA scans and generating accurate radiology reports remains a significant challenge. This paper introduces Abn-BLIP (Abnormality-aligned Bootstrapping Language-Image Pretraining), an advanced diagnosis model designed to align abnormal findings to generate the accuracy and comprehensiveness of radiology reports. By leveraging learnable queries and cross-modal attention mechanisms, our model demonstrates superior performance in detecting abnormalities, reducing missed findings, and generating structured reports compared to existing methods. Our experiments show that Abn-BLIP outperforms state-of-the-art medical vision-language models and 3D report generation methods in both accuracy and clinical relevance. These results highlight the potential of integrating multimodal learning strategies for improving radiology reporting. The source code is available at https://github.com/zzs95/abn-blip.

We present a simplified, task-agnostic multi-modal pre-training approach that can accept either video or text input, or both for a variety of end tasks. Existing pre-training are task-specific by adopting either a single cross-modal encoder that requires both modalities, limiting their use for retrieval-style end tasks or more complex multitask learning with two unimodal encoders, limiting early cross-modal fusion. We instead introduce new pretraining masking schemes that better mix across modalities (e.g. by forcing masks for text to predict the closest video embeddings) while also maintaining separability (e.g. unimodal predictions are sometimes required, without using all the input). Experimental results show strong performance across a wider range of tasks than any previous methods, often outperforming task-specific pre-training. Code is made available at https://github.com/pytorch/fairseq/tree/main/examples/MMPT.