ae_id,subject_id,onset_day,resolution_day,meddra_pt,meddra_soc,ctcae_grade,serious_flag,related_to_treatment_flag,action_taken,outcome,is_crs,crs_grade_lee,is_icans,icans_grade_astct,is_hepatotoxicity,is_tma,special_interest_flag
AE0000001,S00001,5,9,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0000002,S00001,374,378,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0000003,S00001,313,341,Nausea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000004,S00001,192,196,Anaemia,Blood and lymphatic system,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0000005,S00001,60,74,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,Hospitalization,Unknown,N,0,N,0,N,Y,Y
AE0000006,S00001,702,726,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000007,S00001,603,612,Infusion related reaction,"Injury, poisoning, procedural",3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000008,S00001,339,348,Anaemia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000009,S00001,93,98,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000010,S00001,205,209,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000011,S00001,657,663,Seizure,Nervous system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000012,S00001,2,17,Mucosal inflammation,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000013,S00001,428,440,Pyrexia,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000014,S00001,316,333,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000015,S00001,322,344,Neutropenia,Blood and lymphatic system,4,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000016,S00001,632,634,Pyrexia,General disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000017,S00001,725,741,Confusional state,Psychiatric disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000018,S00001,550,567,Anaemia,Blood and lymphatic system,5,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000019,S00001,543,551,Sepsis,Infections and infestations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000020,S00001,107,134,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000021,S00001,91,92,Hypotension,Vascular disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000022,S00001,582,583,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000023,S00001,66,78,Mucosal inflammation,Gastrointestinal disorders,3,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0000024,S00001,578,582,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000025,S00001,592,606,Nausea,Gastrointestinal disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000026,S00001,358,376,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0000027,S00001,127,141,Neutropenia,Blood and lymphatic system,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000028,S00001,686,713,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,Drug interrupted,Unknown,N,0,N,0,N,Y,Y
AE0000029,S00001,553,557,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,Drug interrupted,Unknown,N,0,N,0,N,Y,Y
AE0000030,S00001,88,107,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000031,S00001,137,146,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000032,S00001,453,477,Complement activation,Immune system disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000033,S00002,223,246,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000034,S00002,173,185,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000035,S00002,613,630,Alanine aminotransferase increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000036,S00002,491,515,Bilirubin increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000037,S00002,176,205,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000038,S00002,550,553,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000039,S00002,139,149,Aphasia,Nervous system disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000040,S00002,45,54,Aphasia,Nervous system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000041,S00002,444,447,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0000042,S00002,291,303,Hypotension,Vascular disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000043,S00002,474,498,Pyrexia,General disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000044,S00002,232,240,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000045,S00002,351,377,Tremor,Nervous system disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000046,S00002,369,380,Cytomegalovirus infection,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000047,S00003,5,13,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0000048,S00003,3,20,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0000049,S00003,55,69,Seizure,Nervous system disorders,5,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000050,S00003,535,549,Vomiting,Gastrointestinal disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000051,S00003,615,635,Bilirubin increased,Investigations,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0000052,S00003,536,548,Vomiting,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000053,S00003,6,8,Diarrhoea,Gastrointestinal disorders,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000054,S00003,421,431,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000055,S00003,125,126,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000056,S00003,492,510,Thrombocytopenia,Blood and lymphatic system,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000057,S00003,17,41,Pyrexia,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000058,S00003,512,522,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000059,S00003,649,661,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000060,S00003,156,158,Confusional state,Psychiatric disorders,1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0000061,S00003,44,52,Tachycardia,Cardiac disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000062,S00003,344,357,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000063,S00003,130,158,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000064,S00003,537,540,Fatigue,General disorders,3,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0000065,S00003,676,681,Neutropenia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000066,S00003,546,560,Cough,"Respiratory, thoracic, mediastinal",2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000067,S00003,481,488,Tachycardia,Cardiac disorders,2,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0000068,S00003,729,737,Bilirubin increased,Investigations,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000069,S00003,675,704,Sepsis,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000070,S00003,566,570,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,Drug interrupted,Unknown,N,0,N,0,N,Y,Y
AE0000071,S00004,426,434,Alanine aminotransferase increased,Investigations,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000072,S00004,389,398,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,Dose modification,Recovered,N,0,N,0,N,Y,Y
AE0000073,S00004,694,699,Bilirubin increased,Investigations,3,Y,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0000074,S00004,634,636,Anaemia,Blood and lymphatic system,3,Y,N,None,Recovering,N,0,N,0,N,N,N
AE0000075,S00004,426,431,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000076,S00004,447,450,Fatigue,General disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000077,S00004,220,241,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000078,S00004,638,655,Seizure,Nervous system disorders,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0000079,S00004,204,205,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,Y,Y
AE0000080,S00004,692,694,Neutropenia,Blood and lymphatic system,5,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000081,S00004,675,686,Sepsis,Infections and infestations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000082,S00004,494,497,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Dose modification,Recovered,N,0,N,0,N,Y,Y
AE0000083,S00004,323,340,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000084,S00004,637,650,Aphasia,Nervous system disorders,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000085,S00004,622,643,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000086,S00004,502,514,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000087,S00004,263,281,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000088,S00004,17,44,Aphasia,Nervous system disorders,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000089,S00004,370,394,Cytomegalovirus infection,Infections and infestations,3,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0000090,S00004,259,279,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000091,S00004,9,24,Confusional state,Psychiatric disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000092,S00004,439,448,Hypogammaglobulinaemia,Immune system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000093,S00004,627,643,Anaemia,Blood and lymphatic system,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000094,S00004,720,742,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000095,S00004,489,504,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000096,S00004,675,686,Confusional state,Psychiatric disorders,1,N,Y,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0000097,S00004,497,513,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000098,S00004,708,725,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0000099,S00004,11,36,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000100,S00004,380,381,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000101,S00004,572,573,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000102,S00004,146,152,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000103,S00004,21,29,Aspartate aminotransferase increased,Investigations,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000104,S00004,523,536,Aphasia,Nervous system disorders,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000105,S00004,559,578,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000106,S00004,232,244,Diarrhoea,Gastrointestinal disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000107,S00004,574,597,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000108,S00004,559,572,Diarrhoea,Gastrointestinal disorders,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000109,S00004,646,670,Tachycardia,Cardiac disorders,1,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0000110,S00004,291,320,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000111,S00004,462,463,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000112,S00004,10,18,Fatigue,General disorders,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000113,S00004,144,157,Anaemia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000114,S00006,43,63,Sepsis,Infections and infestations,5,Y,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0000115,S00006,61,64,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000116,S00006,429,440,Anaemia,Blood and lymphatic system,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000117,S00006,162,182,Tremor,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000118,S00006,551,568,Cytomegalovirus infection,Infections and infestations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000119,S00006,543,546,Headache,Nervous system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000120,S00006,589,611,Aphasia,Nervous system disorders,3,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000121,S00006,120,148,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000122,S00006,549,561,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000123,S00006,672,700,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000124,S00006,98,119,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000125,S00006,421,425,Fatigue,General disorders,2,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0000126,S00006,159,178,Tachycardia,Cardiac disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000127,S00006,464,484,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000128,S00006,715,726,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0000129,S00006,279,302,Hypogammaglobulinaemia,Immune system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000130,S00006,150,177,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000131,S00006,191,217,Neutropenia,Blood and lymphatic system,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000132,S00006,581,607,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000133,S00006,585,600,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0000134,S00006,147,153,Neutropenia,Blood and lymphatic system,5,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000135,S00006,469,483,Alanine aminotransferase increased,Investigations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000136,S00006,585,613,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000137,S00006,49,63,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000138,S00007,6,17,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0000139,S00007,284,294,Neutropenia,Blood and lymphatic system,5,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0000140,S00007,267,287,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000141,S00007,729,752,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000142,S00007,553,556,Hypotension,Vascular disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000143,S00007,111,136,Diarrhoea,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000144,S00007,418,419,Seizure,Nervous system disorders,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000145,S00007,313,326,Vomiting,Gastrointestinal disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000146,S00007,582,589,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0000147,S00007,397,405,Aphasia,Nervous system disorders,1,N,N,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0000148,S00007,725,737,Thrombocytopenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000149,S00007,721,732,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000150,S00007,115,132,Complement activation,Immune system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000151,S00007,473,501,Aphasia,Nervous system disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000152,S00007,124,146,Fatigue,General disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000153,S00007,425,432,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000154,S00007,293,301,Seizure,Nervous system disorders,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000155,S00007,181,188,Confusional state,Psychiatric disorders,1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0000156,S00007,507,515,Seizure,Nervous system disorders,2,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0000157,S00007,254,275,Cytomegalovirus infection,Infections and infestations,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000158,S00007,187,197,Neutropenia,Blood and lymphatic system,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000159,S00007,51,55,Vomiting,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000160,S00007,422,435,Aphasia,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000161,S00007,332,334,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000162,S00007,487,498,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000163,S00007,95,121,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0000164,S00007,279,294,Neutropenia,Blood and lymphatic system,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000165,S00007,93,101,Complement activation,Immune system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0000166,S00007,425,444,Neutropenia,Blood and lymphatic system,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0000167,S00007,76,86,Hypotension,Vascular disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000168,S00007,651,675,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000169,S00007,340,357,Fatigue,General disorders,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0000170,S00008,658,666,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,None,Unknown,N,0,N,0,N,Y,Y
AE0000171,S00008,624,651,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,Hospitalization,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0000172,S00008,42,56,Infusion related reaction,"Injury, poisoning, procedural",3,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000173,S00008,354,360,Aspartate aminotransferase increased,Investigations,5,Y,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000174,S00008,465,483,Seizure,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000175,S00008,59,77,Cough,"Respiratory, thoracic, mediastinal",3,Y,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000176,S00008,116,127,Seizure,Nervous system disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000177,S00008,386,399,Nausea,Gastrointestinal disorders,3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000178,S00008,475,482,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000179,S00008,499,524,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0000180,S00008,399,412,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000181,S00008,485,488,Complement activation,Immune system disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000182,S00008,106,129,Sepsis,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000183,S00008,634,641,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000184,S00008,122,127,Seizure,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000185,S00008,375,398,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0000186,S00008,594,623,Complement activation,Immune system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000187,S00008,597,612,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0000188,S00008,690,706,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000189,S00008,256,280,Hypotension,Vascular disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000190,S00008,21,28,Fatigue,General disorders,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000191,S00008,444,452,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000192,S00008,517,520,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000193,S00008,490,495,Aphasia,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000194,S00008,716,737,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000195,S00008,60,70,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0000196,S00008,199,213,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000197,S00009,562,564,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000198,S00009,424,429,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,Y,Y
AE0000199,S00009,419,428,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,Y,Y
AE0000200,S00009,25,27,Pyrexia,General disorders,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000201,S00009,331,338,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000202,S00009,316,336,Aphasia,Nervous system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000203,S00009,360,369,Alanine aminotransferase increased,Investigations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000204,S00009,661,668,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0000205,S00009,197,210,Pyrexia,General disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000206,S00009,557,580,Thrombocytopenia,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000207,S00009,256,285,Mucosal inflammation,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000208,S00009,412,437,Hypotension,Vascular disorders,2,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0000209,S00009,215,231,Aphasia,Nervous system disorders,1,N,Y,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0000210,S00010,161,188,Complement activation,Immune system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0000211,S00010,383,404,Pyrexia,General disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000212,S00010,649,657,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000213,S00010,720,742,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000214,S00010,438,439,Tachycardia,Cardiac disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000215,S00010,11,39,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000216,S00010,547,560,Vomiting,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000217,S00010,7,31,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000218,S00011,263,265,Thrombocytopenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000219,S00011,388,416,Vomiting,Gastrointestinal disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0000220,S00011,115,132,Aspartate aminotransferase increased,Investigations,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000221,S00011,531,537,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000222,S00011,272,295,Hypotension,Vascular disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000223,S00011,392,400,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000224,S00011,543,548,Cytomegalovirus infection,Infections and infestations,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000225,S00011,480,502,Seizure,Nervous system disorders,4,N,N,None,Fatal,N,0,N,0,N,N,N
AE0000226,S00011,492,500,Confusional state,Psychiatric disorders,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000227,S00011,77,101,Infusion related reaction,"Injury, poisoning, procedural",5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000228,S00011,592,595,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000229,S00011,407,423,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000230,S00011,131,150,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000231,S00011,261,275,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000232,S00011,323,341,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0000233,S00011,275,304,Vomiting,Gastrointestinal disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000234,S00011,491,499,Pyrexia,General disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000235,S00011,358,374,Thrombocytopenia,Blood and lymphatic system,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000236,S00011,633,636,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000237,S00012,7,11,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0000238,S00012,140,150,Hypotension,Vascular disorders,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000239,S00012,136,155,Tachycardia,Cardiac disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0000240,S00012,637,665,Confusional state,Psychiatric disorders,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000241,S00012,42,61,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000242,S00012,176,179,Anaemia,Blood and lymphatic system,1,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0000243,S00012,715,737,Nausea,Gastrointestinal disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000244,S00012,149,159,Confusional state,Psychiatric disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000245,S00012,338,351,Pyrexia,General disorders,3,Y,Y,None,Recovering,N,0,N,0,N,N,N
AE0000246,S00012,159,179,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0000247,S00012,329,350,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0000248,S00012,436,455,Headache,Nervous system disorders,3,Y,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000249,S00012,199,213,Confusional state,Psychiatric disorders,2,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0000250,S00012,354,357,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000251,S00012,19,35,Aphasia,Nervous system disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0000252,S00012,459,471,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000253,S00012,80,108,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0000254,S00012,208,226,Hypogammaglobulinaemia,Immune system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000255,S00012,314,321,Anaemia,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000256,S00012,146,174,Hypotension,Vascular disorders,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000257,S00012,669,685,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000258,S00012,155,180,Diarrhoea,Gastrointestinal disorders,2,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0000259,S00012,692,717,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0000260,S00012,538,558,Tremor,Nervous system disorders,3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0000261,S00012,269,289,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000262,S00012,705,734,Pyrexia,General disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000263,S00012,446,464,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000264,S00012,423,435,Mucosal inflammation,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000265,S00012,192,206,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000266,S00012,268,274,Pyrexia,General disorders,3,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000267,S00012,487,500,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000268,S00012,674,680,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000269,S00012,332,338,Headache,Nervous system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000270,S00012,299,306,Thrombotic microangiopathy,Blood and lymphatic system,5,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0000271,S00012,391,401,Neutropenia,Blood and lymphatic system,5,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0000272,S00012,94,103,Vomiting,Gastrointestinal disorders,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000273,S00012,372,385,Sepsis,Infections and infestations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000274,S00012,135,141,Confusional state,Psychiatric disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000275,S00012,102,127,Aspartate aminotransferase increased,Investigations,1,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0000276,S00013,11,27,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0000277,S00013,130,134,Bilirubin increased,Investigations,3,Y,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000278,S00013,545,553,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000279,S00013,126,128,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000280,S00013,31,33,Fatigue,General disorders,2,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0000281,S00013,60,62,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000282,S00013,653,671,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000283,S00013,180,183,Anaemia,Blood and lymphatic system,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000284,S00013,612,613,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000285,S00013,12,15,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000286,S00013,280,296,Thrombocytopenia,Blood and lymphatic system,5,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0000287,S00013,520,533,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000288,S00013,125,146,Complement activation,Immune system disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000289,S00013,393,413,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000290,S00013,533,550,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0000291,S00013,171,196,Sepsis,Infections and infestations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000292,S00013,20,21,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000293,S00013,503,519,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000294,S00013,489,512,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000295,S00013,669,675,Bilirubin increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000296,S00013,604,610,Cough,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000297,S00013,496,512,Fatigue,General disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000298,S00013,648,667,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000299,S00013,307,320,Aspartate aminotransferase increased,Investigations,3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0000300,S00013,485,498,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000301,S00013,372,377,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000302,S00013,8,33,Diarrhoea,Gastrointestinal disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000303,S00013,412,421,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000304,S00013,412,417,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000305,S00013,475,496,Confusional state,Psychiatric disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000306,S00013,59,81,Pyrexia,General disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0000307,S00013,139,150,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000308,S00013,112,127,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000309,S00013,55,61,Bilirubin increased,Investigations,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000310,S00013,122,132,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0000311,S00013,604,615,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000312,S00013,283,290,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0000313,S00013,104,106,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Drug interrupted,Fatal,N,0,N,0,N,N,N
AE0000314,S00013,702,704,Neutropenia,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000315,S00013,468,478,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000316,S00013,258,265,Alanine aminotransferase increased,Investigations,5,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000317,S00013,374,390,Bilirubin increased,Investigations,3,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000318,S00013,483,506,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000319,S00014,7,12,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0000320,S00014,5,25,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,None,Not recovered,N,0,N,0,N,Y,Y
AE0000321,S00014,193,218,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0000322,S00014,468,476,Alanine aminotransferase increased,Investigations,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0000323,S00014,519,539,Hypotension,Vascular disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000324,S00014,557,579,Cytomegalovirus infection,Infections and infestations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000325,S00014,107,118,Nausea,Gastrointestinal disorders,3,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000326,S00014,28,31,Thrombocytopenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0000327,S00014,329,350,Aspartate aminotransferase increased,Investigations,3,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0000328,S00014,535,560,Hypotension,Vascular disorders,2,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0000329,S00014,483,506,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000330,S00014,226,243,Aphasia,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000331,S00014,333,349,Aspartate aminotransferase increased,Investigations,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0000332,S00014,689,704,Complement activation,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000333,S00014,53,82,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000334,S00014,407,410,Aphasia,Nervous system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000335,S00014,181,183,Aspartate aminotransferase increased,Investigations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000336,S00014,240,252,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000337,S00014,370,378,Hypotension,Vascular disorders,1,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0000338,S00014,598,619,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,Hospitalization,Recovered,N,0,N,0,N,Y,Y
AE0000339,S00014,258,274,Headache,Nervous system disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000340,S00014,197,225,Bilirubin increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000341,S00014,707,708,Anaemia,Blood and lymphatic system,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000342,S00014,439,442,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0000343,S00014,456,481,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0000344,S00014,285,306,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000345,S00014,349,356,Hypotension,Vascular disorders,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000346,S00014,489,496,Alanine aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000347,S00014,456,473,Nausea,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000348,S00014,675,687,Complement activation,Immune system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000349,S00014,48,58,Aspartate aminotransferase increased,Investigations,3,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0000350,S00014,692,712,Sepsis,Infections and infestations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000351,S00014,345,358,Bilirubin increased,Investigations,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000352,S00014,424,435,Aspartate aminotransferase increased,Investigations,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0000353,S00016,130,151,Aspartate aminotransferase increased,Investigations,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000354,S00016,708,717,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000355,S00016,717,732,Cytomegalovirus infection,Infections and infestations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000356,S00016,276,304,Fatigue,General disorders,1,N,N,Dose modification,Unknown,N,0,N,0,N,N,N
AE0000357,S00016,597,609,Alanine aminotransferase increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000358,S00016,657,681,Anaemia,Blood and lymphatic system,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0000359,S00016,399,423,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000360,S00016,311,336,Confusional state,Psychiatric disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000361,S00016,26,32,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0000362,S00016,396,416,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000363,S00016,18,43,Confusional state,Psychiatric disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000364,S00016,117,119,Bilirubin increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000365,S00016,648,662,Seizure,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000366,S00016,530,534,Aphasia,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000367,S00016,700,721,Pyrexia,General disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000368,S00016,549,566,Neutropenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000369,S00016,286,294,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000370,S00016,372,373,Cough,"Respiratory, thoracic, mediastinal",3,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000371,S00016,442,469,Aspartate aminotransferase increased,Investigations,1,N,N,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0000372,S00016,511,539,Thrombocytopenia,Blood and lymphatic system,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000373,S00016,331,337,Seizure,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000374,S00018,351,377,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000375,S00018,288,289,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000376,S00018,327,342,Anaemia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000377,S00018,521,541,Sepsis,Infections and infestations,2,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000378,S00018,339,341,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000379,S00018,433,439,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000380,S00019,6,22,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0000381,S00019,595,624,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000382,S00019,246,255,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000383,S00019,285,292,Cytomegalovirus infection,Infections and infestations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000384,S00019,522,547,Sepsis,Infections and infestations,5,N,Y,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0000385,S00019,207,226,Complement activation,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000386,S00019,84,87,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000387,S00019,73,91,Neutropenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000388,S00019,180,201,Bilirubin increased,Investigations,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000389,S00019,237,265,Tremor,Nervous system disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000390,S00019,285,313,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000391,S00019,706,728,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0000392,S00019,287,292,Aphasia,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000393,S00019,706,721,Alanine aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000394,S00019,257,286,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000395,S00019,548,553,Seizure,Nervous system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000396,S00019,633,646,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000397,S00019,552,555,Fatigue,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000398,S00019,607,631,Tremor,Nervous system disorders,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0000399,S00019,69,93,Hypogammaglobulinaemia,Immune system disorders,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000400,S00019,635,647,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0000401,S00019,155,173,Tachycardia,Cardiac disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000402,S00019,525,548,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000403,S00019,560,574,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000404,S00019,425,433,Mucosal inflammation,Gastrointestinal disorders,5,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0000405,S00019,153,161,Vomiting,Gastrointestinal disorders,2,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0000406,S00019,75,80,Cytomegalovirus infection,Infections and infestations,4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000407,S00019,202,217,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000408,S00019,513,520,Bilirubin increased,Investigations,5,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000409,S00019,115,120,Pyrexia,General disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000410,S00020,3,5,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0000411,S00020,119,121,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000412,S00020,34,39,Bilirubin increased,Investigations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000413,S00020,126,131,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000414,S00020,530,550,Vomiting,Gastrointestinal disorders,3,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000415,S00020,605,617,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000416,S00020,707,726,Seizure,Nervous system disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000417,S00020,595,605,Complement activation,Immune system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000418,S00020,441,444,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000419,S00020,103,116,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000420,S00020,695,707,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000421,S00020,364,375,Sepsis,Infections and infestations,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000422,S00020,651,668,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,Y,Y
AE0000423,S00020,67,78,Sepsis,Infections and infestations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000424,S00020,467,478,Aphasia,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000425,S00020,78,106,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0000426,S00020,525,549,Tachycardia,Cardiac disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000427,S00020,622,631,Bilirubin increased,Investigations,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000428,S00020,153,157,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0000429,S00020,550,575,Tremor,Nervous system disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000430,S00020,461,480,Sepsis,Infections and infestations,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000431,S00020,407,419,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000432,S00020,543,564,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000433,S00020,612,619,Hypogammaglobulinaemia,Immune system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000434,S00020,270,286,Aspartate aminotransferase increased,Investigations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0000435,S00020,369,383,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000436,S00020,671,686,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000437,S00021,7,9,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0000438,S00021,592,605,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000439,S00021,314,341,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000440,S00021,198,210,Thrombocytopenia,Blood and lymphatic system,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000441,S00021,429,430,Infusion related reaction,"Injury, poisoning, procedural",5,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0000442,S00021,508,523,Fatigue,General disorders,1,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0000443,S00021,12,23,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000444,S00021,459,478,Seizure,Nervous system disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000445,S00021,527,555,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000446,S00021,520,532,Tremor,Nervous system disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000447,S00021,182,190,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000448,S00021,634,644,Aspartate aminotransferase increased,Investigations,3,N,N,None,Unknown,N,0,N,0,N,N,N
AE0000449,S00021,485,505,Anaemia,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000450,S00021,310,336,Hypogammaglobulinaemia,Immune system disorders,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000451,S00021,361,363,Tachycardia,Cardiac disorders,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0000452,S00021,532,559,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000453,S00021,198,213,Aspartate aminotransferase increased,Investigations,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000454,S00021,537,542,Anaemia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000455,S00021,564,582,Tremor,Nervous system disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000456,S00021,311,314,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000457,S00021,58,83,Tremor,Nervous system disorders,2,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0000458,S00021,338,351,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000459,S00021,446,450,Vomiting,Gastrointestinal disorders,2,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0000460,S00021,297,320,Tachycardia,Cardiac disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000461,S00021,518,545,Neutropenia,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000462,S00021,520,549,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000463,S00021,556,566,Mucosal inflammation,Gastrointestinal disorders,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000464,S00021,658,671,Anaemia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000465,S00022,214,240,Cytomegalovirus infection,Infections and infestations,3,Y,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000466,S00022,320,325,Headache,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0000467,S00022,22,46,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000468,S00022,481,483,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000469,S00022,22,33,Thrombocytopenia,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000470,S00022,18,32,Headache,Nervous system disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000471,S00022,30,49,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0000472,S00022,123,126,Sepsis,Infections and infestations,3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0000473,S00022,324,337,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0000474,S00022,192,205,Thrombocytopenia,Blood and lymphatic system,4,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0000475,S00022,442,460,Aspartate aminotransferase increased,Investigations,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0000476,S00022,280,304,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000477,S00022,478,489,Fatigue,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000478,S00022,51,79,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000479,S00023,240,262,Hypotension,Vascular disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000480,S00023,162,167,Confusional state,Psychiatric disorders,1,N,N,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0000481,S00023,544,559,Headache,Nervous system disorders,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000482,S00023,156,185,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000483,S00023,27,32,Tachycardia,Cardiac disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000484,S00023,470,477,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000485,S00023,118,147,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000486,S00023,251,268,Bilirubin increased,Investigations,3,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0000487,S00023,523,529,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000488,S00023,721,737,Vomiting,Gastrointestinal disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000489,S00023,624,645,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000490,S00023,22,37,Thrombocytopenia,Blood and lymphatic system,4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000491,S00023,213,236,Tremor,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000492,S00023,568,572,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000493,S00023,224,225,Fatigue,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000494,S00023,652,659,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000495,S00024,5,10,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0000496,S00024,73,81,Hypotension,Vascular disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000497,S00024,575,583,Nausea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000498,S00024,715,727,Aphasia,Nervous system disorders,4,Y,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0000499,S00024,352,363,Hypogammaglobulinaemia,Immune system disorders,3,Y,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000500,S00024,443,459,Cough,"Respiratory, thoracic, mediastinal",3,Y,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000501,S00024,159,183,Confusional state,Psychiatric disorders,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0000502,S00024,565,585,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000503,S00024,174,192,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000504,S00024,209,231,Aphasia,Nervous system disorders,4,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000505,S00024,341,369,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000506,S00024,620,622,Infusion related reaction,"Injury, poisoning, procedural",3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0000507,S00024,316,324,Fatigue,General disorders,3,Y,Y,None,Recovering,N,0,N,0,N,N,N
AE0000508,S00024,661,680,Anaemia,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000509,S00024,291,314,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000510,S00024,507,525,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000511,S00024,351,379,Confusional state,Psychiatric disorders,1,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0000512,S00024,253,282,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0000513,S00024,312,336,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0000514,S00024,372,400,Neutropenia,Blood and lymphatic system,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000515,S00024,234,259,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000516,S00024,494,503,Vomiting,Gastrointestinal disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000517,S00024,388,390,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0000518,S00024,364,387,Vomiting,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0000519,S00024,491,493,Fatigue,General disorders,5,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000520,S00024,27,40,Pyrexia,General disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000521,S00024,378,405,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000522,S00024,360,375,Aphasia,Nervous system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000523,S00024,611,629,Thrombocytopenia,Blood and lymphatic system,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000524,S00024,463,483,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000525,S00024,239,240,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000526,S00024,556,560,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000527,S00025,6,26,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0000528,S00025,581,605,Tachycardia,Cardiac disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000529,S00025,279,290,Neutropenia,Blood and lymphatic system,3,Y,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0000530,S00025,14,34,Sepsis,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000531,S00025,695,718,Confusional state,Psychiatric disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000532,S00025,323,340,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000533,S00025,562,573,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000534,S00025,523,536,Anaemia,Blood and lymphatic system,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0000535,S00025,154,161,Tremor,Nervous system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000536,S00025,570,588,Alanine aminotransferase increased,Investigations,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000537,S00025,219,240,Cytomegalovirus infection,Infections and infestations,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000538,S00025,472,482,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000539,S00025,456,459,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000540,S00025,356,358,Headache,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000541,S00025,385,393,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000542,S00025,65,87,Tremor,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000543,S00025,326,336,Hypogammaglobulinaemia,Immune system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000544,S00025,390,413,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000545,S00025,432,448,Complement activation,Immune system disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000546,S00025,594,607,Hypotension,Vascular disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000547,S00025,171,196,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000548,S00025,417,435,Hypotension,Vascular disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000549,S00025,365,371,Alanine aminotransferase increased,Investigations,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000550,S00025,633,634,Pyrexia,General disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000551,S00025,511,525,Aspartate aminotransferase increased,Investigations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000552,S00025,126,130,Anaemia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000553,S00025,381,397,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000554,S00025,395,415,Confusional state,Psychiatric disorders,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000555,S00025,389,407,Pyrexia,General disorders,2,N,N,Dose modification,Fatal,N,0,N,0,N,N,N
AE0000556,S00025,461,466,Sepsis,Infections and infestations,5,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000557,S00025,531,555,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000558,S00025,613,638,Fatigue,General disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000559,S00025,663,679,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000560,S00025,27,40,Thrombocytopenia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000561,S00025,568,586,Hypotension,Vascular disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000562,S00025,552,573,Fatigue,General disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000563,S00025,455,465,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000564,S00025,0,28,Confusional state,Psychiatric disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000565,S00026,35,56,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000566,S00026,335,358,Pyrexia,General disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000567,S00026,132,142,Thrombotic microangiopathy,Blood and lymphatic system,5,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0000568,S00026,132,145,Sepsis,Infections and infestations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000569,S00026,133,161,Hypotension,Vascular disorders,5,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0000570,S00026,440,465,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0000571,S00026,125,149,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000572,S00026,21,23,Thrombocytopenia,Blood and lymphatic system,3,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0000573,S00026,543,560,Tremor,Nervous system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000574,S00026,638,662,Sepsis,Infections and infestations,5,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000575,S00026,582,594,Neutropenia,Blood and lymphatic system,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000576,S00026,528,535,Diarrhoea,Gastrointestinal disorders,3,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000577,S00026,76,92,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000578,S00027,73,93,Hepatocellular injury,Hepatobiliary disorders,3,Y,Y,Tocilizumab,Recovered,Y,0,N,0,Y,N,Y
AE0000579,S00027,416,424,Complement activation,Immune system disorders,1,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0000580,S00027,25,44,Headache,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000581,S00027,223,226,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000582,S00027,714,735,Hypotension,Vascular disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0000583,S00027,473,499,Complement activation,Immune system disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000584,S00027,503,504,Nausea,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000585,S00027,498,512,Complement activation,Immune system disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000586,S00027,127,144,Cytomegalovirus infection,Infections and infestations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000587,S00027,282,289,Tachycardia,Cardiac disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000588,S00027,158,167,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000589,S00027,103,117,Neutropenia,Blood and lymphatic system,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0000590,S00027,54,58,Vomiting,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000591,S00027,343,346,Tremor,Nervous system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000592,S00027,29,38,Hypotension,Vascular disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000593,S00029,650,651,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000594,S00029,675,680,Aphasia,Nervous system disorders,2,N,Y,Drug interrupted,Fatal,N,0,N,0,N,N,N
AE0000595,S00029,263,280,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0000596,S00029,538,565,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000597,S00029,616,637,Tachycardia,Cardiac disorders,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000598,S00029,639,653,Cytomegalovirus infection,Infections and infestations,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000599,S00029,51,66,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000600,S00029,329,350,Thrombotic microangiopathy,Blood and lymphatic system,5,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0000601,S00029,237,252,Complement activation,Immune system disorders,1,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0000602,S00029,540,554,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000603,S00029,632,642,Hypotension,Vascular disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000604,S00029,291,292,Bilirubin increased,Investigations,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000605,S00030,5,23,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0000606,S00030,664,673,Pyrexia,General disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000607,S00030,391,394,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,Concomitant medication,Not recovered,N,0,N,0,N,Y,Y
AE0000608,S00030,428,445,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000609,S00030,312,333,Headache,Nervous system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000610,S00030,477,486,Bilirubin increased,Investigations,2,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0000611,S00030,458,460,Hypotension,Vascular disorders,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0000612,S00030,112,139,Sepsis,Infections and infestations,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000613,S00030,281,284,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000614,S00030,84,111,Neutropenia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000615,S00030,146,163,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000616,S00030,263,289,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000617,S00030,378,405,Bilirubin increased,Investigations,1,N,Y,Drug interrupted,Fatal,N,0,N,0,N,N,N
AE0000618,S00030,704,716,Cytomegalovirus infection,Infections and infestations,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000619,S00030,385,408,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000620,S00030,230,247,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0000621,S00030,126,141,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0000622,S00030,268,288,Thrombocytopenia,Blood and lymphatic system,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0000623,S00030,182,209,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000624,S00030,232,247,Bilirubin increased,Investigations,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000625,S00030,249,272,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000626,S00030,157,164,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000627,S00030,357,386,Aphasia,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000628,S00030,504,523,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000629,S00030,374,401,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000630,S00030,384,402,Headache,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0000631,S00030,543,560,Diarrhoea,Gastrointestinal disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000632,S00030,609,636,Tremor,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0000633,S00030,426,431,Alanine aminotransferase increased,Investigations,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000634,S00030,385,386,Mucosal inflammation,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000635,S00030,3,15,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000636,S00031,7,24,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0000637,S00031,534,540,Diarrhoea,Gastrointestinal disorders,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000638,S00031,329,333,Neutropenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000639,S00031,616,621,Vomiting,Gastrointestinal disorders,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0000640,S00031,282,288,Tremor,Nervous system disorders,3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000641,S00031,619,646,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0000642,S00031,388,392,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000643,S00031,283,298,Tremor,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000644,S00031,197,204,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000645,S00031,239,253,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0000646,S00031,103,120,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000647,S00031,211,236,Aspartate aminotransferase increased,Investigations,1,N,N,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0000648,S00031,433,441,Alanine aminotransferase increased,Investigations,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0000649,S00031,492,504,Confusional state,Psychiatric disorders,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000650,S00031,476,487,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0000651,S00031,627,638,Confusional state,Psychiatric disorders,2,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0000652,S00031,684,702,Vomiting,Gastrointestinal disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000653,S00031,198,227,Thrombocytopenia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000654,S00031,537,545,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000655,S00031,313,319,Alanine aminotransferase increased,Investigations,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000656,S00031,82,83,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000657,S00031,375,397,Bilirubin increased,Investigations,3,N,N,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0000658,S00031,537,552,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000659,S00031,81,93,Sepsis,Infections and infestations,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0000660,S00031,448,470,Bilirubin increased,Investigations,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000661,S00031,644,649,Bilirubin increased,Investigations,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000662,S00031,625,639,Fatigue,General disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000663,S00031,618,639,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000664,S00031,171,183,Nausea,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000665,S00031,348,375,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000666,S00031,654,664,Aphasia,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000667,S00031,384,410,Diarrhoea,Gastrointestinal disorders,1,N,N,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0000668,S00031,534,557,Bilirubin increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000669,S00031,44,71,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000670,S00031,438,459,Aspartate aminotransferase increased,Investigations,2,N,N,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0000671,S00031,406,413,Tachycardia,Cardiac disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000672,S00031,49,71,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000673,S00031,302,312,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000674,S00032,240,252,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000675,S00032,430,447,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000676,S00032,5,6,Sepsis,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000677,S00032,585,593,Nausea,Gastrointestinal disorders,5,N,Y,Hospitalization,Fatal,N,0,N,0,N,N,N
AE0000678,S00032,368,394,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000679,S00032,2,15,Vomiting,Gastrointestinal disorders,3,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0000680,S00032,201,225,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000681,S00032,139,159,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000682,S00032,78,96,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000683,S00032,671,680,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000684,S00032,345,349,Headache,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000685,S00032,126,154,Diarrhoea,Gastrointestinal disorders,2,N,N,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0000686,S00032,206,230,Anaemia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000687,S00032,62,89,Sepsis,Infections and infestations,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000688,S00033,34,58,Anaemia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000689,S00033,21,39,Infusion related reaction,"Injury, poisoning, procedural",5,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000690,S00033,656,682,Alanine aminotransferase increased,Investigations,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000691,S00033,638,647,Bilirubin increased,Investigations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0000692,S00033,189,215,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000693,S00033,5,14,Aspartate aminotransferase increased,Investigations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000694,S00033,205,222,Hypotension,Vascular disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000695,S00033,531,540,Confusional state,Psychiatric disorders,3,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0000696,S00033,88,115,Pyrexia,General disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000697,S00033,371,374,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0000698,S00033,544,564,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000699,S00033,397,414,Bilirubin increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000700,S00033,286,300,Cytomegalovirus infection,Infections and infestations,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000701,S00033,659,660,Alanine aminotransferase increased,Investigations,3,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000702,S00033,615,631,Aphasia,Nervous system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000703,S00033,558,586,Tremor,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000704,S00033,379,380,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000705,S00033,125,137,Thrombocytopenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000706,S00033,83,108,Aphasia,Nervous system disorders,3,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0000707,S00033,24,42,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000708,S00033,323,327,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000709,S00033,457,460,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000710,S00033,551,569,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000711,S00033,554,565,Complement activation,Immune system disorders,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0000712,S00033,690,719,Fatigue,General disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0000713,S00033,238,244,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000714,S00033,618,639,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000715,S00033,593,606,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000716,S00033,466,467,Sepsis,Infections and infestations,4,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000717,S00033,360,383,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0000718,S00034,661,674,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000719,S00034,90,106,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000720,S00034,715,732,Headache,Nervous system disorders,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000721,S00034,49,50,Tachycardia,Cardiac disorders,3,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0000722,S00034,641,651,Pyrexia,General disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000723,S00034,478,492,Hypotension,Vascular disorders,3,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0000724,S00034,383,405,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0000725,S00034,34,35,Tremor,Nervous system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000726,S00034,224,248,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000727,S00034,500,523,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000728,S00034,529,556,Thrombocytopenia,Blood and lymphatic system,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000729,S00034,476,502,Headache,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000730,S00034,40,42,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000731,S00034,461,478,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000732,S00035,150,169,Sepsis,Infections and infestations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000733,S00035,675,699,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000734,S00035,651,671,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0000735,S00035,99,120,Hypogammaglobulinaemia,Immune system disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000736,S00035,687,716,Fatigue,General disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000737,S00035,593,605,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000738,S00035,277,287,Fatigue,General disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000739,S00035,29,36,Seizure,Nervous system disorders,1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0000740,S00035,292,297,Alanine aminotransferase increased,Investigations,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000741,S00035,590,610,Thrombocytopenia,Blood and lymphatic system,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0000742,S00035,284,288,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000743,S00035,400,416,Aphasia,Nervous system disorders,4,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000744,S00035,689,701,Neutropenia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000745,S00035,414,421,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000746,S00035,78,95,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000747,S00035,437,443,Complement activation,Immune system disorders,3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0000748,S00035,411,433,Thrombocytopenia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000749,S00035,502,520,Bilirubin increased,Investigations,3,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000750,S00035,473,487,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000751,S00035,150,159,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000752,S00035,559,566,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000753,S00035,333,353,Tremor,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000754,S00035,570,598,Complement activation,Immune system disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000755,S00035,512,516,Hypotension,Vascular disorders,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000756,S00036,265,274,Bilirubin increased,Investigations,2,N,N,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0000757,S00036,656,678,Anaemia,Blood and lymphatic system,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000758,S00036,55,62,Sepsis,Infections and infestations,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000759,S00036,672,693,Nausea,Gastrointestinal disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000760,S00036,561,589,Alanine aminotransferase increased,Investigations,3,N,N,None,Unknown,N,0,N,0,N,N,N
AE0000761,S00036,458,466,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000762,S00036,556,568,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0000763,S00036,202,213,Seizure,Nervous system disorders,2,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0000764,S00036,389,396,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000765,S00036,364,372,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000766,S00036,459,467,Complement activation,Immune system disorders,2,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0000767,S00036,654,677,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000768,S00036,575,580,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000769,S00036,517,523,Tachycardia,Cardiac disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000770,S00036,444,460,Neutropenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000771,S00036,636,656,Seizure,Nervous system disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000772,S00036,14,21,Sepsis,Infections and infestations,5,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000773,S00037,243,247,Hypoxia,"Respiratory, thoracic, mediastinal",4,Y,Y,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0000774,S00037,585,609,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000775,S00037,693,720,Seizure,Nervous system disorders,2,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0000776,S00037,233,245,Alanine aminotransferase increased,Investigations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000777,S00037,595,617,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000778,S00037,534,558,Neutropenia,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000779,S00037,247,267,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000780,S00037,19,31,Hypogammaglobulinaemia,Immune system disorders,2,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0000781,S00037,174,197,Pyrexia,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000782,S00037,420,421,Hypotension,Vascular disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000783,S00037,236,245,Pyrexia,General disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000784,S00037,78,81,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000785,S00037,379,382,Tremor,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000786,S00038,215,233,Sepsis,Infections and infestations,3,Y,N,None,Recovering,N,0,N,0,N,N,N
AE0000787,S00038,407,432,Aphasia,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000788,S00038,275,279,Hypotension,Vascular disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000789,S00038,673,692,Aspartate aminotransferase increased,Investigations,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000790,S00038,75,104,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000791,S00038,442,466,Bilirubin increased,Investigations,2,N,Y,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0000792,S00038,556,576,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0000793,S00038,505,528,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000794,S00038,243,245,Hypotension,Vascular disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0000795,S00038,546,550,Confusional state,Psychiatric disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000796,S00038,139,145,Tremor,Nervous system disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0000797,S00039,615,636,Sepsis,Infections and infestations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000798,S00039,653,666,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000799,S00039,472,477,Aspartate aminotransferase increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000800,S00039,402,422,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000801,S00039,204,219,Tachycardia,Cardiac disorders,3,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000802,S00039,374,386,Diarrhoea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000803,S00039,438,448,Pyrexia,General disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000804,S00039,43,51,Tachycardia,Cardiac disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000805,S00039,435,456,Sepsis,Infections and infestations,5,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000806,S00039,505,516,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000807,S00039,13,22,Confusional state,Psychiatric disorders,1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0000808,S00039,267,277,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000809,S00039,235,262,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000810,S00039,239,249,Neutropenia,Blood and lymphatic system,3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0000811,S00039,214,222,Complement activation,Immune system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000812,S00040,2,21,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0000813,S00040,213,230,Vomiting,Gastrointestinal disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000814,S00040,166,188,Neutropenia,Blood and lymphatic system,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0000815,S00040,439,462,Fatigue,General disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000816,S00040,343,347,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0000817,S00040,497,518,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000818,S00040,577,593,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000819,S00040,186,203,Neutropenia,Blood and lymphatic system,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000820,S00040,395,397,Aphasia,Nervous system disorders,4,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0000821,S00040,146,175,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000822,S00040,174,197,Complement activation,Immune system disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0000823,S00040,631,639,Tachycardia,Cardiac disorders,4,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000824,S00040,71,89,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000825,S00040,566,585,Nausea,Gastrointestinal disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0000826,S00040,436,464,Thrombocytopenia,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000827,S00040,79,107,Sepsis,Infections and infestations,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0000828,S00040,527,549,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000829,S00040,74,78,Tachycardia,Cardiac disorders,3,N,Y,Dose modification,Unknown,N,0,N,0,N,N,N
AE0000830,S00040,225,239,Confusional state,Psychiatric disorders,4,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000831,S00040,568,570,Seizure,Nervous system disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000832,S00040,8,9,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000833,S00040,267,278,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000834,S00040,661,682,Aphasia,Nervous system disorders,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000835,S00040,623,630,Aspartate aminotransferase increased,Investigations,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000836,S00040,335,336,Sepsis,Infections and infestations,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0000837,S00040,185,201,Thrombocytopenia,Blood and lymphatic system,3,N,N,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0000838,S00040,465,468,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0000839,S00040,649,650,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000840,S00040,288,298,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000841,S00040,655,657,Hypotension,Vascular disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000842,S00040,94,102,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000843,S00040,497,524,Pyrexia,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000844,S00040,430,444,Cytomegalovirus infection,Infections and infestations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000845,S00041,1,27,Infusion related reaction,"Injury, poisoning, procedural",3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000846,S00041,638,646,Aphasia,Nervous system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000847,S00041,662,673,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Not recovered,N,0,N,0,N,Y,Y
AE0000848,S00041,146,169,Neutropenia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000849,S00041,265,282,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,None,Recovering,N,0,N,0,N,Y,Y
AE0000850,S00041,447,457,Neutropenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000851,S00041,442,468,Aspartate aminotransferase increased,Investigations,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0000852,S00041,114,130,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000853,S00041,117,128,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000854,S00041,532,561,Thrombocytopenia,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000855,S00041,645,662,Thrombocytopenia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000856,S00041,398,404,Cough,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000857,S00041,190,201,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0000858,S00041,659,662,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000859,S00041,335,355,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0000860,S00041,566,579,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000861,S00041,384,402,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0000862,S00041,68,96,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Recovering,N,0,N,0,N,Y,Y
AE0000863,S00042,1,19,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0000864,S00042,255,281,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0000865,S00042,392,412,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000866,S00042,313,339,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000867,S00042,663,669,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000868,S00042,685,705,Headache,Nervous system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000869,S00042,323,334,Neutropenia,Blood and lymphatic system,3,Y,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000870,S00042,297,325,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000871,S00042,608,627,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000872,S00042,678,707,Alanine aminotransferase increased,Investigations,3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000873,S00042,545,557,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000874,S00042,681,692,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000875,S00042,70,93,Neutropenia,Blood and lymphatic system,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000876,S00042,90,108,Bilirubin increased,Investigations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000877,S00042,285,305,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0000878,S00042,719,732,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000879,S00042,200,214,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000880,S00042,633,653,Confusional state,Psychiatric disorders,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000881,S00042,592,615,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000882,S00042,425,428,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000883,S00042,473,488,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000884,S00042,107,129,Complement activation,Immune system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000885,S00042,223,247,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0000886,S00042,535,545,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000887,S00042,36,55,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000888,S00042,55,74,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000889,S00042,247,274,Neutropenia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000890,S00042,222,230,Anaemia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000891,S00042,708,726,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000892,S00042,435,440,Fatigue,General disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0000893,S00042,164,181,Thrombocytopenia,Blood and lymphatic system,4,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000894,S00042,238,257,Pyrexia,General disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000895,S00042,432,457,Sepsis,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000896,S00042,463,484,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000897,S00042,200,215,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000898,S00042,184,202,Sepsis,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000899,S00043,4,23,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0000900,S00043,11,18,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0000901,S00043,523,535,Hypotension,Vascular disorders,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000902,S00043,634,641,Complement activation,Immune system disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000903,S00043,187,205,Pyrexia,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000904,S00043,268,269,Neutropenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000905,S00043,573,586,Mucosal inflammation,Gastrointestinal disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0000906,S00043,177,180,Seizure,Nervous system disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000907,S00043,672,698,Vomiting,Gastrointestinal disorders,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0000908,S00043,702,726,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000909,S00043,120,145,Neutropenia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000910,S00043,28,57,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000911,S00043,598,616,Hypotension,Vascular disorders,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000912,S00043,513,523,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000913,S00043,369,393,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0000914,S00043,332,334,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000915,S00043,320,337,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0000916,S00043,134,150,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0000917,S00043,45,56,Seizure,Nervous system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000918,S00043,418,444,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000919,S00043,614,618,Sepsis,Infections and infestations,4,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0000920,S00043,223,241,Tremor,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000921,S00043,497,520,Seizure,Nervous system disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000922,S00043,605,615,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000923,S00043,416,421,Tachycardia,Cardiac disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000924,S00043,276,289,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0000925,S00043,315,322,Tremor,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000926,S00043,163,186,Aspartate aminotransferase increased,Investigations,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0000927,S00043,671,696,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000928,S00043,477,506,Aphasia,Nervous system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000929,S00044,418,441,Seizure,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000930,S00044,2,12,Sepsis,Infections and infestations,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000931,S00044,230,238,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000932,S00044,405,419,Cytomegalovirus infection,Infections and infestations,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000933,S00044,453,466,Aphasia,Nervous system disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000934,S00044,265,280,Alanine aminotransferase increased,Investigations,5,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000935,S00044,383,401,Confusional state,Psychiatric disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000936,S00044,439,456,Bilirubin increased,Investigations,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000937,S00044,99,105,Thrombocytopenia,Blood and lymphatic system,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0000938,S00044,23,25,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000939,S00044,419,434,Fatigue,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000940,S00044,65,89,Cytomegalovirus infection,Infections and infestations,4,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0000941,S00044,81,108,Aspartate aminotransferase increased,Investigations,3,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0000942,S00044,194,195,Neutropenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000943,S00044,725,735,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000944,S00045,484,499,Headache,Nervous system disorders,3,Y,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000945,S00045,561,572,Hypotension,Vascular disorders,3,Y,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000946,S00045,40,55,Tremor,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000947,S00045,514,542,Headache,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000948,S00045,678,705,Aphasia,Nervous system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000949,S00045,147,148,Tremor,Nervous system disorders,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0000950,S00045,479,496,Headache,Nervous system disorders,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0000951,S00045,392,408,Neutropenia,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000952,S00045,728,739,Confusional state,Psychiatric disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000953,S00045,362,371,Bilirubin increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000954,S00045,445,466,Cytomegalovirus infection,Infections and infestations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000955,S00045,304,333,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000956,S00045,395,414,Hypotension,Vascular disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0000957,S00045,60,81,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000958,S00045,214,217,Aspartate aminotransferase increased,Investigations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000959,S00045,227,230,Anaemia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000960,S00045,226,247,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000961,S00045,298,318,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000962,S00045,45,68,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000963,S00045,25,39,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000964,S00045,43,45,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000965,S00045,399,403,Cough,"Respiratory, thoracic, mediastinal",2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000966,S00045,208,209,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000967,S00045,664,671,Tremor,Nervous system disorders,3,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0000968,S00045,509,528,Anaemia,Blood and lymphatic system,4,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000969,S00045,103,120,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0000970,S00045,422,440,Alanine aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000971,S00045,3,26,Headache,Nervous system disorders,4,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0000972,S00045,194,195,Aphasia,Nervous system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000973,S00045,313,314,Bilirubin increased,Investigations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000974,S00046,1,10,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0000975,S00046,539,565,Infusion related reaction,"Injury, poisoning, procedural",3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0000976,S00046,339,366,Sepsis,Infections and infestations,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000977,S00046,662,686,Tachycardia,Cardiac disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000978,S00046,585,599,Bilirubin increased,Investigations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000979,S00046,690,710,Thrombocytopenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000980,S00046,422,427,Anaemia,Blood and lymphatic system,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0000981,S00046,412,431,Mucosal inflammation,Gastrointestinal disorders,2,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0000982,S00046,310,330,Nausea,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000983,S00046,198,217,Seizure,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000984,S00046,206,228,Confusional state,Psychiatric disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000985,S00046,120,124,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000986,S00046,724,725,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000987,S00046,313,334,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000988,S00046,703,727,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000989,S00046,341,344,Anaemia,Blood and lymphatic system,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0000990,S00046,449,473,Headache,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0000991,S00046,187,210,Cough,"Respiratory, thoracic, mediastinal",4,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0000992,S00046,589,607,Hypoxia,"Respiratory, thoracic, mediastinal",5,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0000993,S00046,385,414,Thrombocytopenia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000994,S00046,529,539,Anaemia,Blood and lymphatic system,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0000995,S00046,186,206,Vomiting,Gastrointestinal disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0000996,S00046,163,191,Cytomegalovirus infection,Infections and infestations,2,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0000997,S00046,165,166,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0000998,S00046,649,665,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0000999,S00046,20,25,Tremor,Nervous system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001000,S00046,598,614,Confusional state,Psychiatric disorders,1,N,N,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0001001,S00046,549,574,Alanine aminotransferase increased,Investigations,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0001002,S00046,230,232,Hypotension,Vascular disorders,1,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0001003,S00046,187,212,Confusional state,Psychiatric disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001004,S00046,430,431,Anaemia,Blood and lymphatic system,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001005,S00047,466,484,Seizure,Nervous system disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0001006,S00047,644,670,Thrombocytopenia,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001007,S00047,499,519,Aphasia,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001008,S00047,657,670,Headache,Nervous system disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001009,S00047,29,46,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001010,S00047,663,670,Hypogammaglobulinaemia,Immune system disorders,5,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001011,S00047,300,304,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001012,S00047,603,604,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001013,S00047,314,324,Headache,Nervous system disorders,1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0001014,S00047,286,303,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001015,S00047,113,129,Aspartate aminotransferase increased,Investigations,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001016,S00047,571,572,Anaemia,Blood and lymphatic system,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001017,S00047,488,508,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001018,S00047,544,565,Anaemia,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001019,S00047,400,411,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001020,S00047,409,411,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001021,S00047,538,559,Hypotension,Vascular disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001022,S00047,585,613,Alanine aminotransferase increased,Investigations,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001023,S00047,216,244,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001024,S00047,138,167,Diarrhoea,Gastrointestinal disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001025,S00047,6,28,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001026,S00047,719,731,Seizure,Nervous system disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001027,S00047,2,20,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001028,S00047,268,297,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001029,S00047,726,752,Aphasia,Nervous system disorders,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001030,S00048,597,622,Seizure,Nervous system disorders,4,Y,N,Hospitalization,Fatal,N,0,N,0,N,N,N
AE0001031,S00048,440,451,Sepsis,Infections and infestations,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001032,S00048,664,669,Pyrexia,General disorders,3,Y,Y,None,Recovering,N,0,N,0,N,N,N
AE0001033,S00048,316,327,Aspartate aminotransferase increased,Investigations,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001034,S00048,50,62,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001035,S00048,452,464,Fatigue,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001036,S00048,466,493,Aphasia,Nervous system disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001037,S00048,192,203,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001038,S00048,355,356,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001039,S00048,346,355,Diarrhoea,Gastrointestinal disorders,3,N,N,None,Fatal,N,0,N,0,N,N,N
AE0001040,S00048,225,230,Thrombotic microangiopathy,Blood and lymphatic system,5,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0001041,S00048,514,522,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001042,S00048,221,247,Bilirubin increased,Investigations,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001043,S00048,120,142,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001044,S00048,59,80,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001045,S00048,521,542,Tachycardia,Cardiac disorders,2,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0001046,S00048,656,671,Bilirubin increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001047,S00048,101,102,Bilirubin increased,Investigations,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001048,S00048,641,651,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0001049,S00048,399,406,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001050,S00048,478,500,Thrombocytopenia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001051,S00049,3,17,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0001052,S00049,318,336,Nausea,Gastrointestinal disorders,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0001053,S00049,580,584,Cough,"Respiratory, thoracic, mediastinal",3,Y,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001054,S00049,479,501,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001055,S00049,325,345,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001056,S00049,199,205,Complement activation,Immune system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001057,S00049,307,331,Hypotension,Vascular disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001058,S00049,384,402,Neutropenia,Blood and lymphatic system,5,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001059,S00049,532,553,Thrombotic microangiopathy,Blood and lymphatic system,5,N,N,None,Not recovered,N,0,N,0,N,Y,Y
AE0001060,S00049,383,387,Pyrexia,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001061,S00049,411,426,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001062,S00049,665,671,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,Y,Y
AE0001063,S00049,73,81,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001064,S00049,42,45,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001065,S00049,34,63,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001066,S00049,497,517,Cytomegalovirus infection,Infections and infestations,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001067,S00049,225,243,Anaemia,Blood and lymphatic system,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0001068,S00049,658,679,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001069,S00049,542,550,Aphasia,Nervous system disorders,3,N,N,None,Unknown,N,0,N,0,N,N,N
AE0001070,S00049,249,253,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001071,S00049,199,225,Sepsis,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001072,S00049,480,483,Hypotension,Vascular disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001073,S00049,507,508,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001074,S00049,412,415,Aphasia,Nervous system disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001075,S00049,454,466,Seizure,Nervous system disorders,4,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001076,S00049,342,363,Confusional state,Psychiatric disorders,3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001077,S00049,5,12,Fatigue,General disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001078,S00049,105,107,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001079,S00049,707,726,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001080,S00049,702,731,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001081,S00050,527,540,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001082,S00050,310,329,Thrombocytopenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001083,S00050,253,261,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001084,S00050,193,209,Tremor,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001085,S00050,529,550,Bilirubin increased,Investigations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001086,S00050,459,480,Tremor,Nervous system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0001087,S00050,612,620,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001088,S00050,250,258,Seizure,Nervous system disorders,4,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0001089,S00050,289,313,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001090,S00050,497,514,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001091,S00050,68,87,Thrombocytopenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001092,S00051,9,36,Complement activation,Immune system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001093,S00051,366,389,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001094,S00051,626,648,Alanine aminotransferase increased,Investigations,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0001095,S00051,26,34,Diarrhoea,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001096,S00051,68,90,Aphasia,Nervous system disorders,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001097,S00051,584,595,Sepsis,Infections and infestations,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001098,S00052,61,86,Pyrexia,General disorders,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001099,S00052,82,100,Anaemia,Blood and lymphatic system,3,Y,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0001100,S00052,684,701,Aphasia,Nervous system disorders,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0001101,S00052,516,525,Anaemia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001102,S00052,22,35,Pyrexia,General disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001103,S00052,665,677,Alanine aminotransferase increased,Investigations,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001104,S00052,318,330,Headache,Nervous system disorders,1,N,Y,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0001105,S00052,133,162,Anaemia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001106,S00052,237,250,Headache,Nervous system disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001107,S00052,169,194,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001108,S00052,369,395,Headache,Nervous system disorders,1,N,N,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0001109,S00052,708,711,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001110,S00052,460,484,Sepsis,Infections and infestations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001111,S00052,599,617,Pyrexia,General disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001112,S00053,4,13,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0001113,S00053,9,36,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001114,S00053,711,722,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001115,S00053,53,79,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001116,S00053,221,244,Sepsis,Infections and infestations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001117,S00053,706,711,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001118,S00053,658,660,Thrombocytopenia,Blood and lymphatic system,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001119,S00053,190,218,Neutropenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001120,S00053,185,202,Seizure,Nervous system disorders,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001121,S00053,425,448,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001122,S00053,243,256,Mucosal inflammation,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001123,S00053,710,735,Vomiting,Gastrointestinal disorders,5,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0001124,S00053,476,480,Sepsis,Infections and infestations,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001125,S00053,593,606,Seizure,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001126,S00053,280,289,Tremor,Nervous system disorders,2,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0001127,S00053,180,183,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001128,S00053,11,24,Sepsis,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001129,S00053,433,441,Aspartate aminotransferase increased,Investigations,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001130,S00053,62,85,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0001131,S00053,455,474,Aphasia,Nervous system disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001132,S00053,654,680,Nausea,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001133,S00053,171,183,Aphasia,Nervous system disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001134,S00053,390,415,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001135,S00053,184,207,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001136,S00053,184,204,Seizure,Nervous system disorders,5,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001137,S00053,53,61,Hypotension,Vascular disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001138,S00053,704,727,Confusional state,Psychiatric disorders,2,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0001139,S00053,510,512,Neutropenia,Blood and lymphatic system,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001140,S00053,680,699,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001141,S00053,252,281,Pyrexia,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001142,S00053,43,59,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001143,S00053,273,294,Tachycardia,Cardiac disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0001144,S00053,109,119,Nausea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001145,S00054,13,21,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,3,Y,Y,Corticosteroids,Recovered,N,0,Y,3,N,N,Y
AE0001146,S00054,581,604,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001147,S00054,694,698,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001148,S00054,125,137,Headache,Nervous system disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001149,S00054,535,560,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001150,S00054,29,58,Sepsis,Infections and infestations,3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001151,S00054,257,271,Aspartate aminotransferase increased,Investigations,3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001152,S00054,129,158,Aspartate aminotransferase increased,Investigations,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001153,S00054,460,465,Alanine aminotransferase increased,Investigations,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0001154,S00054,143,147,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001155,S00054,404,419,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001156,S00054,100,102,Confusional state,Psychiatric disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001157,S00054,405,422,Aphasia,Nervous system disorders,4,N,N,None,Unknown,N,0,N,0,N,N,N
AE0001158,S00054,722,747,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001159,S00054,726,752,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Recovering,N,0,N,0,N,Y,Y
AE0001160,S00054,589,598,Aspartate aminotransferase increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001161,S00054,602,623,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0001162,S00054,455,468,Hypoxia,"Respiratory, thoracic, mediastinal",5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001163,S00054,224,228,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001164,S00054,351,371,Sepsis,Infections and infestations,2,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0001165,S00054,92,97,Tachycardia,Cardiac disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001166,S00054,475,480,Fatigue,General disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001167,S00054,296,323,Anaemia,Blood and lymphatic system,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001168,S00054,686,700,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001169,S00054,500,525,Hypotension,Vascular disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001170,S00054,208,225,Bilirubin increased,Investigations,3,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0001171,S00054,600,610,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001172,S00054,462,475,Sepsis,Infections and infestations,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001173,S00054,250,255,Tachycardia,Cardiac disorders,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001174,S00054,304,320,Bilirubin increased,Investigations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001175,S00054,683,710,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001176,S00054,501,519,Pyrexia,General disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0001177,S00055,2,5,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0001178,S00055,5,29,Bilirubin increased,Investigations,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001179,S00055,461,487,Tremor,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001180,S00055,329,348,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001181,S00055,211,225,Thrombotic microangiopathy,Blood and lymphatic system,5,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0001182,S00055,243,265,Headache,Nervous system disorders,2,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0001183,S00055,103,119,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0001184,S00055,159,185,Diarrhoea,Gastrointestinal disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001185,S00055,656,660,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001186,S00055,584,598,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001187,S00055,99,116,Headache,Nervous system disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0001188,S00055,699,704,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001189,S00055,462,484,Tremor,Nervous system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001190,S00055,45,64,Hypogammaglobulinaemia,Immune system disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001191,S00055,472,500,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001192,S00055,422,424,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001193,S00055,109,114,Thrombocytopenia,Blood and lymphatic system,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0001194,S00055,291,310,Sepsis,Infections and infestations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001195,S00055,370,376,Seizure,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001196,S00055,281,307,Pyrexia,General disorders,3,N,N,None,Unknown,N,0,N,0,N,N,N
AE0001197,S00055,23,38,Aphasia,Nervous system disorders,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0001198,S00055,134,160,Seizure,Nervous system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001199,S00056,3,16,Cytokine release syndrome,Immune system disorders,4,Y,Y,Tocilizumab,Recovered with sequelae,Y,4,N,0,N,N,Y
AE0001200,S00056,570,594,Sepsis,Infections and infestations,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001201,S00056,340,353,Alanine aminotransferase increased,Investigations,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001202,S00056,118,122,Bilirubin increased,Investigations,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001203,S00056,101,111,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001204,S00056,45,55,Aphasia,Nervous system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001205,S00056,474,498,Tachycardia,Cardiac disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001206,S00056,420,422,Infusion related reaction,"Injury, poisoning, procedural",3,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001207,S00056,523,549,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001208,S00056,19,34,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001209,S00056,87,106,Vomiting,Gastrointestinal disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001210,S00056,253,254,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001211,S00056,413,427,Seizure,Nervous system disorders,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001212,S00056,215,242,Seizure,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001213,S00056,641,644,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001214,S00056,452,464,Thrombocytopenia,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001215,S00056,74,100,Vomiting,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001216,S00056,248,259,Complement activation,Immune system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001217,S00056,543,556,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001218,S00056,229,242,Complement activation,Immune system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001219,S00056,421,450,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001220,S00056,489,511,Aphasia,Nervous system disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001221,S00056,159,175,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,Hospitalization,Recovered,N,0,N,0,N,Y,Y
AE0001222,S00056,215,223,Anaemia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001223,S00056,576,587,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001224,S00056,647,651,Fatigue,General disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001225,S00056,224,239,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001226,S00056,85,96,Aspartate aminotransferase increased,Investigations,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001227,S00056,288,310,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0001228,S00056,124,130,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001229,S00056,442,467,Thrombocytopenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001230,S00056,228,252,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001231,S00056,300,313,Complement activation,Immune system disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001232,S00057,506,529,Hypotension,Vascular disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001233,S00057,703,710,Cytomegalovirus infection,Infections and infestations,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0001234,S00057,647,648,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001235,S00057,1,29,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001236,S00057,302,323,Anaemia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001237,S00057,137,154,Complement activation,Immune system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001238,S00057,256,271,Thrombocytopenia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001239,S00057,618,621,Tremor,Nervous system disorders,1,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0001240,S00057,2,14,Pyrexia,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001241,S00057,184,192,Cytomegalovirus infection,Infections and infestations,3,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001242,S00057,366,384,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001243,S00057,10,35,Tremor,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001244,S00057,585,600,Cough,"Respiratory, thoracic, mediastinal",2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001245,S00057,499,517,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0001246,S00057,434,451,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001247,S00057,164,169,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001248,S00057,134,157,Anaemia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001249,S00059,261,284,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0001250,S00059,201,211,Aphasia,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001251,S00059,720,744,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001252,S00059,106,122,Vomiting,Gastrointestinal disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001253,S00059,601,620,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001254,S00059,181,202,Seizure,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001255,S00059,22,32,Bilirubin increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001256,S00059,364,376,Tachycardia,Cardiac disorders,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001257,S00059,588,616,Nausea,Gastrointestinal disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001258,S00059,237,256,Mucosal inflammation,Gastrointestinal disorders,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001259,S00059,537,545,Pyrexia,General disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001260,S00059,338,366,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001261,S00059,727,740,Cytomegalovirus infection,Infections and infestations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001262,S00059,530,535,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001263,S00059,147,162,Mucosal inflammation,Gastrointestinal disorders,3,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001264,S00059,455,462,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001265,S00061,2,7,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0001266,S00061,9,12,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,2,N,Y,Corticosteroids,Recovered,N,0,Y,2,N,N,Y
AE0001267,S00061,74,90,Complement activation,Immune system disorders,1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0001268,S00061,699,718,Headache,Nervous system disorders,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001269,S00061,482,486,Aphasia,Nervous system disorders,4,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001270,S00061,698,705,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001271,S00061,522,548,Confusional state,Psychiatric disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0001272,S00061,622,648,Confusional state,Psychiatric disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001273,S00061,579,608,Hypotension,Vascular disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001274,S00061,603,621,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001275,S00061,298,312,Pyrexia,General disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001276,S00061,267,273,Anaemia,Blood and lymphatic system,2,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0001277,S00061,100,102,Hypoxia,"Respiratory, thoracic, mediastinal",5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001278,S00061,582,596,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0001279,S00061,148,163,Seizure,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001280,S00061,54,79,Vomiting,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001281,S00061,669,677,Tachycardia,Cardiac disorders,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001282,S00061,683,688,Confusional state,Psychiatric disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001283,S00061,623,651,Tachycardia,Cardiac disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001284,S00061,297,314,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001285,S00061,161,165,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001286,S00061,417,435,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001287,S00061,611,639,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001288,S00061,598,602,Headache,Nervous system disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001289,S00061,677,681,Headache,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001290,S00061,71,75,Hypotension,Vascular disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001291,S00061,63,79,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001292,S00062,359,361,Pyrexia,General disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001293,S00062,424,434,Nausea,Gastrointestinal disorders,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0001294,S00062,256,271,Aspartate aminotransferase increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001295,S00062,633,648,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001296,S00062,307,330,Aphasia,Nervous system disorders,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001297,S00062,448,468,Hypoxia,"Respiratory, thoracic, mediastinal",3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0001298,S00062,221,239,Pyrexia,General disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001299,S00062,634,646,Pyrexia,General disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001300,S00062,639,666,Aspartate aminotransferase increased,Investigations,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001301,S00062,262,289,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,Y,Y
AE0001302,S00062,277,280,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001303,S00062,481,499,Fatigue,General disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001304,S00063,544,570,Sepsis,Infections and infestations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001305,S00063,649,672,Pyrexia,General disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001306,S00063,505,511,Aphasia,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001307,S00063,21,24,Thrombocytopenia,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001308,S00063,20,36,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001309,S00063,534,546,Tachycardia,Cardiac disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0001310,S00063,654,661,Cough,"Respiratory, thoracic, mediastinal",4,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001311,S00063,119,139,Aspartate aminotransferase increased,Investigations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001312,S00063,505,506,Aphasia,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001313,S00063,475,477,Sepsis,Infections and infestations,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001314,S00064,5,18,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0001315,S00064,13,30,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,2,N,Y,Corticosteroids,Recovered,N,0,Y,2,N,N,Y
AE0001316,S00064,325,352,Tachycardia,Cardiac disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001317,S00064,184,212,Fatigue,General disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001318,S00064,450,457,Seizure,Nervous system disorders,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001319,S00064,628,644,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0001320,S00064,440,450,Cytomegalovirus infection,Infections and infestations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001321,S00064,603,617,Aphasia,Nervous system disorders,2,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0001322,S00064,520,545,Headache,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001323,S00064,422,440,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001324,S00064,173,174,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001325,S00064,90,93,Aphasia,Nervous system disorders,5,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001326,S00064,483,502,Alanine aminotransferase increased,Investigations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001327,S00064,213,222,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001328,S00064,90,106,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001329,S00064,4,18,Tremor,Nervous system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001330,S00064,615,621,Tremor,Nervous system disorders,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0001331,S00064,609,636,Nausea,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001332,S00064,256,264,Hypotension,Vascular disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001333,S00064,427,442,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001334,S00064,502,517,Bilirubin increased,Investigations,1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0001335,S00064,684,700,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001336,S00064,545,554,Confusional state,Psychiatric disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001337,S00064,238,247,Sepsis,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001338,S00064,81,89,Sepsis,Infections and infestations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001339,S00064,300,314,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0001340,S00064,105,122,Thrombocytopenia,Blood and lymphatic system,4,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001341,S00064,69,87,Diarrhoea,Gastrointestinal disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0001342,S00064,122,137,Neutropenia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001343,S00064,628,632,Pyrexia,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001344,S00064,559,561,Pyrexia,General disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001345,S00064,457,461,Complement activation,Immune system disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001346,S00064,154,176,Bilirubin increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001347,S00065,1,17,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0001348,S00065,674,686,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001349,S00065,324,326,Sepsis,Infections and infestations,3,Y,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001350,S00065,716,742,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001351,S00065,252,256,Aphasia,Nervous system disorders,1,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0001352,S00065,281,284,Headache,Nervous system disorders,1,N,N,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0001353,S00065,594,604,Cytomegalovirus infection,Infections and infestations,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001354,S00065,62,76,Sepsis,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001355,S00065,266,293,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001356,S00065,535,539,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001357,S00065,577,592,Alanine aminotransferase increased,Investigations,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001358,S00065,456,466,Tachycardia,Cardiac disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001359,S00065,714,726,Sepsis,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001360,S00065,664,679,Nausea,Gastrointestinal disorders,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0001361,S00065,235,245,Headache,Nervous system disorders,4,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001362,S00065,244,251,Hypotension,Vascular disorders,2,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0001363,S00065,185,196,Confusional state,Psychiatric disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001364,S00065,382,407,Pyrexia,General disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0001365,S00065,597,608,Diarrhoea,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001366,S00065,702,724,Sepsis,Infections and infestations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001367,S00065,485,499,Hypogammaglobulinaemia,Immune system disorders,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001368,S00065,690,691,Bilirubin increased,Investigations,5,N,N,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0001369,S00065,630,644,Bilirubin increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001370,S00065,141,154,Sepsis,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001371,S00065,165,184,Thrombocytopenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001372,S00065,210,229,Hypotension,Vascular disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001373,S00065,316,345,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001374,S00065,503,526,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001375,S00065,452,481,Bilirubin increased,Investigations,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001376,S00065,307,322,Neutropenia,Blood and lymphatic system,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001377,S00065,655,676,Bilirubin increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001378,S00066,500,511,Pyrexia,General disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0001379,S00066,656,670,Complement activation,Immune system disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001380,S00066,410,420,Tremor,Nervous system disorders,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0001381,S00066,554,572,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,None,Unknown,N,0,N,0,N,Y,Y
AE0001382,S00066,529,546,Aphasia,Nervous system disorders,5,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001383,S00066,630,641,Headache,Nervous system disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001384,S00066,597,615,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001385,S00066,330,358,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001386,S00066,215,238,Cytomegalovirus infection,Infections and infestations,3,N,N,None,Unknown,N,0,N,0,N,N,N
AE0001387,S00067,442,463,Cytomegalovirus infection,Infections and infestations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001388,S00067,81,93,Complement activation,Immune system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001389,S00067,179,190,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001390,S00067,172,188,Thrombocytopenia,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001391,S00067,586,615,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001392,S00067,647,671,Confusional state,Psychiatric disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001393,S00067,629,633,Hypotension,Vascular disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001394,S00067,340,343,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0001395,S00067,698,701,Complement activation,Immune system disorders,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0001396,S00067,699,715,Thrombocytopenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001397,S00067,288,302,Nausea,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001398,S00067,59,84,Thrombocytopenia,Blood and lymphatic system,2,N,Y,Dose modification,Unknown,N,0,N,0,N,N,N
AE0001399,S00067,643,672,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001400,S00067,589,617,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001401,S00067,247,266,Complement activation,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001402,S00068,678,705,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001403,S00068,69,89,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001404,S00068,70,90,Tachycardia,Cardiac disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001405,S00068,5,26,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0001406,S00068,15,21,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001407,S00068,229,239,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,Y,Y
AE0001408,S00068,583,602,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001409,S00068,648,662,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001410,S00068,521,531,Headache,Nervous system disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001411,S00068,584,589,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001412,S00068,604,613,Complement activation,Immune system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001413,S00068,349,378,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001414,S00068,506,534,Alanine aminotransferase increased,Investigations,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001415,S00068,473,493,Aspartate aminotransferase increased,Investigations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001416,S00068,39,68,Neutropenia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001417,S00068,633,659,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0001418,S00068,367,375,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001419,S00068,529,535,Nausea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0001420,S00068,243,259,Bilirubin increased,Investigations,3,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0001421,S00068,466,495,Alanine aminotransferase increased,Investigations,4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001422,S00068,586,606,Seizure,Nervous system disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001423,S00068,180,199,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001424,S00068,460,474,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0001425,S00068,586,610,Aphasia,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001426,S00068,581,584,Seizure,Nervous system disorders,3,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0001427,S00068,326,339,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0001428,S00068,374,391,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001429,S00069,508,535,Hypoxia,"Respiratory, thoracic, mediastinal",3,Y,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0001430,S00069,6,10,Complement activation,Immune system disorders,2,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0001431,S00069,478,501,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001432,S00069,567,592,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001433,S00069,401,408,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001434,S00069,569,584,Sepsis,Infections and infestations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001435,S00069,476,497,Sepsis,Infections and infestations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001436,S00069,362,371,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001437,S00070,197,202,Alanine aminotransferase increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001438,S00070,41,56,Neutropenia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001439,S00070,286,292,Hypogammaglobulinaemia,Immune system disorders,3,Y,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001440,S00070,188,196,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001441,S00070,90,99,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001442,S00070,113,142,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001443,S00070,126,145,Bilirubin increased,Investigations,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001444,S00071,584,590,Sepsis,Infections and infestations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001445,S00071,623,640,Headache,Nervous system disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001446,S00071,123,142,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001447,S00071,30,42,Thrombocytopenia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001448,S00071,25,51,Tachycardia,Cardiac disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001449,S00071,161,174,Tremor,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001450,S00071,652,661,Pyrexia,General disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001451,S00071,135,154,Aphasia,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001452,S00071,402,404,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001453,S00072,389,401,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001454,S00072,634,646,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001455,S00072,586,588,Pyrexia,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001456,S00072,476,480,Seizure,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001457,S00072,505,529,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001458,S00072,442,458,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001459,S00072,321,328,Thrombocytopenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001460,S00072,625,637,Alanine aminotransferase increased,Investigations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001461,S00072,197,221,Thrombocytopenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001462,S00072,120,149,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001463,S00072,595,618,Hypoxia,"Respiratory, thoracic, mediastinal",5,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0001464,S00072,63,71,Bilirubin increased,Investigations,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001465,S00072,49,61,Hypotension,Vascular disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001466,S00072,187,206,Bilirubin increased,Investigations,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001467,S00072,571,594,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001468,S00072,52,71,Aphasia,Nervous system disorders,3,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0001469,S00072,663,684,Neutropenia,Blood and lymphatic system,4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001470,S00072,487,498,Seizure,Nervous system disorders,3,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0001471,S00072,472,481,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001472,S00072,192,217,Headache,Nervous system disorders,1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0001473,S00072,274,295,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001474,S00073,4,10,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,2,N,Y,Corticosteroids,Recovered,N,0,Y,2,N,N,Y
AE0001475,S00073,493,497,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001476,S00073,122,141,Vomiting,Gastrointestinal disorders,2,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0001477,S00073,622,646,Neutropenia,Blood and lymphatic system,5,Y,Y,None,Recovering,N,0,N,0,N,N,N
AE0001478,S00073,58,85,Aphasia,Nervous system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001479,S00073,621,640,Sepsis,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001480,S00073,720,727,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0001481,S00073,367,370,Alanine aminotransferase increased,Investigations,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001482,S00073,610,633,Tremor,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001483,S00073,579,597,Cytomegalovirus infection,Infections and infestations,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001484,S00073,116,129,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001485,S00073,65,69,Confusional state,Psychiatric disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001486,S00073,352,369,Cytomegalovirus infection,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001487,S00073,525,537,Hypogammaglobulinaemia,Immune system disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001488,S00073,644,657,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0001489,S00073,325,328,Aspartate aminotransferase increased,Investigations,2,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0001490,S00073,651,662,Aphasia,Nervous system disorders,4,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0001491,S00073,197,226,Aspartate aminotransferase increased,Investigations,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001492,S00073,628,631,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001493,S00073,663,681,Cytomegalovirus infection,Infections and infestations,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001494,S00073,393,394,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001495,S00073,55,74,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001496,S00073,686,710,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001497,S00073,412,427,Pyrexia,General disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001498,S00073,654,655,Sepsis,Infections and infestations,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001499,S00073,480,481,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001500,S00073,500,513,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001501,S00073,118,125,Tachycardia,Cardiac disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001502,S00073,105,123,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001503,S00073,135,156,Confusional state,Psychiatric disorders,3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001504,S00073,503,506,Bilirubin increased,Investigations,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001505,S00074,345,369,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001506,S00074,13,22,Nausea,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001507,S00074,549,556,Vomiting,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001508,S00074,235,239,Complement activation,Immune system disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001509,S00074,538,545,Pyrexia,General disorders,2,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0001510,S00074,679,698,Hypotension,Vascular disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001511,S00074,405,414,Headache,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001512,S00074,273,299,Diarrhoea,Gastrointestinal disorders,5,N,N,Dose modification,Fatal,N,0,N,0,N,N,N
AE0001513,S00074,149,165,Tachycardia,Cardiac disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001514,S00074,563,587,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001515,S00074,79,103,Sepsis,Infections and infestations,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001516,S00074,299,327,Vomiting,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0001517,S00074,579,592,Infusion related reaction,"Injury, poisoning, procedural",3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001518,S00074,397,403,Seizure,Nervous system disorders,4,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001519,S00074,468,489,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001520,S00074,232,259,Neutropenia,Blood and lymphatic system,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0001521,S00074,244,264,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001522,S00074,681,692,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001523,S00074,136,162,Sepsis,Infections and infestations,4,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0001524,S00074,302,310,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001525,S00074,510,527,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,Hospitalization,Recovered,N,0,N,0,N,Y,Y
AE0001526,S00074,264,281,Pyrexia,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001527,S00076,125,145,Confusional state,Psychiatric disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001528,S00076,613,641,Vomiting,Gastrointestinal disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001529,S00076,371,393,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001530,S00076,266,274,Aspartate aminotransferase increased,Investigations,4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001531,S00076,96,98,Aphasia,Nervous system disorders,5,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001532,S00076,82,93,Headache,Nervous system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0001533,S00076,604,617,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001534,S00076,400,421,Pyrexia,General disorders,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001535,S00076,25,34,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001536,S00076,176,180,Headache,Nervous system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001537,S00076,601,628,Pyrexia,General disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001538,S00076,149,177,Thrombotic microangiopathy,Blood and lymphatic system,5,N,N,Dose modification,Recovering,N,0,N,0,N,Y,Y
AE0001539,S00076,150,177,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001540,S00076,307,319,Hypotension,Vascular disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001541,S00076,249,256,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001542,S00076,436,462,Sepsis,Infections and infestations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001543,S00076,674,691,Neutropenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001544,S00076,8,27,Hypoxia,"Respiratory, thoracic, mediastinal",5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001545,S00076,401,422,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001546,S00076,603,606,Complement activation,Immune system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001547,S00076,566,593,Diarrhoea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001548,S00076,328,350,Thrombocytopenia,Blood and lymphatic system,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001549,S00076,28,51,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001550,S00077,728,757,Bilirubin increased,Investigations,3,Y,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001551,S00077,214,217,Confusional state,Psychiatric disorders,1,N,Y,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0001552,S00077,392,402,Tremor,Nervous system disorders,4,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001553,S00077,642,654,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0001554,S00077,121,143,Anaemia,Blood and lymphatic system,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001555,S00077,671,683,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0001556,S00077,613,632,Sepsis,Infections and infestations,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001557,S00077,572,601,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001558,S00077,705,714,Neutropenia,Blood and lymphatic system,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0001559,S00077,577,600,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0001560,S00077,605,615,Fatigue,General disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001561,S00077,351,362,Neutropenia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001562,S00077,52,58,Cough,"Respiratory, thoracic, mediastinal",3,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0001563,S00077,189,210,Infusion related reaction,"Injury, poisoning, procedural",4,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001564,S00077,134,146,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001565,S00077,235,236,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001566,S00077,97,102,Nausea,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001567,S00077,664,682,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001568,S00077,196,224,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001569,S00077,298,319,Sepsis,Infections and infestations,4,N,Y,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0001570,S00077,103,125,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0001571,S00078,3,7,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0001572,S00078,11,18,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,2,N,Y,Corticosteroids,Recovered,N,0,Y,2,N,N,Y
AE0001573,S00078,527,554,Seizure,Nervous system disorders,4,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0001574,S00078,425,447,Seizure,Nervous system disorders,3,Y,Y,None,Unknown,N,0,N,0,N,N,N
AE0001575,S00078,271,292,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001576,S00078,280,284,Bilirubin increased,Investigations,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001577,S00078,479,497,Headache,Nervous system disorders,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0001578,S00078,519,544,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001579,S00078,627,646,Confusional state,Psychiatric disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001580,S00078,435,454,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001581,S00078,442,460,Headache,Nervous system disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001582,S00078,710,734,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001583,S00078,610,623,Vomiting,Gastrointestinal disorders,3,N,N,Dose modification,Fatal,N,0,N,0,N,N,N
AE0001584,S00078,411,435,Nausea,Gastrointestinal disorders,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001585,S00078,153,177,Mucosal inflammation,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001586,S00078,140,152,Nausea,Gastrointestinal disorders,1,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0001587,S00078,105,123,Aphasia,Nervous system disorders,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0001588,S00078,455,466,Hypotension,Vascular disorders,3,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0001589,S00078,573,585,Seizure,Nervous system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001590,S00078,38,47,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001591,S00078,4,5,Aphasia,Nervous system disorders,3,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001592,S00079,59,79,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001593,S00079,212,232,Seizure,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001594,S00079,252,254,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Not recovered,N,0,N,0,N,Y,Y
AE0001595,S00079,539,543,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001596,S00079,100,102,Anaemia,Blood and lymphatic system,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001597,S00079,282,300,Tachycardia,Cardiac disorders,1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0001598,S00079,231,256,Nausea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001599,S00079,216,241,Aspartate aminotransferase increased,Investigations,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001600,S00079,384,409,Tremor,Nervous system disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001601,S00079,184,198,Fatigue,General disorders,3,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0001602,S00079,522,531,Bilirubin increased,Investigations,2,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0001603,S00079,547,559,Tachycardia,Cardiac disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0001604,S00079,30,55,Mucosal inflammation,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001605,S00079,535,559,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001606,S00080,6,25,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0001607,S00080,541,553,Aspartate aminotransferase increased,Investigations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001608,S00080,646,669,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001609,S00080,536,558,Confusional state,Psychiatric disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001610,S00080,718,744,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001611,S00080,207,226,Sepsis,Infections and infestations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001612,S00080,9,25,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001613,S00080,233,252,Fatigue,General disorders,1,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0001614,S00080,9,36,Fatigue,General disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001615,S00080,579,587,Complement activation,Immune system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001616,S00080,164,175,Mucosal inflammation,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001617,S00080,605,629,Cytomegalovirus infection,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001618,S00080,100,127,Fatigue,General disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001619,S00080,710,724,Aphasia,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001620,S00080,38,58,Neutropenia,Blood and lymphatic system,3,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0001621,S00080,46,66,Cytomegalovirus infection,Infections and infestations,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001622,S00080,176,189,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001623,S00080,352,355,Thrombocytopenia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001624,S00080,182,206,Cytomegalovirus infection,Infections and infestations,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001625,S00080,462,465,Tremor,Nervous system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001626,S00080,361,385,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001627,S00080,438,451,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001628,S00081,5,24,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0001629,S00081,6,19,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,2,N,Y,Corticosteroids,Recovered,N,0,Y,2,N,N,Y
AE0001630,S00081,205,230,Aphasia,Nervous system disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001631,S00081,56,78,Complement activation,Immune system disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0001632,S00081,372,397,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001633,S00081,366,384,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001634,S00081,164,186,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001635,S00081,561,590,Sepsis,Infections and infestations,4,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0001636,S00081,618,634,Confusional state,Psychiatric disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001637,S00081,612,620,Cytomegalovirus infection,Infections and infestations,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001638,S00081,663,666,Thrombocytopenia,Blood and lymphatic system,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0001639,S00081,642,666,Aphasia,Nervous system disorders,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001640,S00081,358,381,Confusional state,Psychiatric disorders,3,N,N,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0001641,S00081,709,718,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001642,S00081,443,450,Alanine aminotransferase increased,Investigations,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001643,S00081,570,580,Seizure,Nervous system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001644,S00081,437,461,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001645,S00081,237,261,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001646,S00081,326,346,Nausea,Gastrointestinal disorders,4,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0001647,S00081,456,472,Fatigue,General disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001648,S00081,298,308,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001649,S00081,715,727,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0001650,S00081,555,584,Aphasia,Nervous system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0001651,S00081,336,340,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001652,S00081,661,677,Aphasia,Nervous system disorders,2,N,N,None,Fatal,N,0,N,0,N,N,N
AE0001653,S00081,352,364,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001654,S00081,253,263,Headache,Nervous system disorders,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001655,S00081,258,260,Seizure,Nervous system disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001656,S00081,522,527,Neutropenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001657,S00081,606,616,Confusional state,Psychiatric disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0001658,S00081,236,256,Cytomegalovirus infection,Infections and infestations,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001659,S00081,687,711,Tremor,Nervous system disorders,2,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0001660,S00081,461,472,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001661,S00081,450,468,Aspartate aminotransferase increased,Investigations,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001662,S00081,473,498,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001663,S00081,382,401,Sepsis,Infections and infestations,3,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001664,S00081,450,477,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001665,S00081,319,320,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001666,S00082,329,339,Sepsis,Infections and infestations,3,N,N,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0001667,S00082,601,615,Alanine aminotransferase increased,Investigations,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001668,S00082,352,354,Aphasia,Nervous system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001669,S00082,689,705,Hypogammaglobulinaemia,Immune system disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001670,S00082,265,279,Aspartate aminotransferase increased,Investigations,3,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0001671,S00082,293,301,Cough,"Respiratory, thoracic, mediastinal",4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001672,S00082,102,127,Thrombocytopenia,Blood and lymphatic system,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001673,S00082,604,614,Hypotension,Vascular disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001674,S00082,25,49,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001675,S00082,496,503,Diarrhoea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001676,S00082,400,406,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001677,S00082,549,558,Headache,Nervous system disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001678,S00082,537,566,Thrombocytopenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001679,S00082,427,455,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,None,Not recovered,N,0,N,0,N,Y,Y
AE0001680,S00082,88,116,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001681,S00082,114,123,Seizure,Nervous system disorders,5,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0001682,S00082,287,305,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001683,S00082,177,197,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0001684,S00082,672,684,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001685,S00083,3,16,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0001686,S00083,74,91,Sepsis,Infections and infestations,5,Y,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001687,S00083,488,494,Confusional state,Psychiatric disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0001688,S00083,524,538,Cytomegalovirus infection,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001689,S00083,421,429,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0001690,S00083,555,580,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001691,S00083,457,463,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001692,S00083,484,487,Complement activation,Immune system disorders,4,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0001693,S00083,223,224,Aphasia,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001694,S00083,335,362,Bilirubin increased,Investigations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001695,S00083,135,138,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001696,S00083,351,352,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001697,S00083,66,87,Diarrhoea,Gastrointestinal disorders,1,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0001698,S00083,234,241,Vomiting,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001699,S00083,514,534,Neutropenia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001700,S00083,640,646,Headache,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001701,S00083,70,98,Bilirubin increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001702,S00083,152,154,Thrombocytopenia,Blood and lymphatic system,5,N,Y,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0001703,S00083,103,121,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001704,S00083,588,605,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001705,S00083,359,380,Neutropenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001706,S00083,642,658,Thrombocytopenia,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001707,S00083,367,395,Cough,"Respiratory, thoracic, mediastinal",4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001708,S00083,610,618,Nausea,Gastrointestinal disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001709,S00083,320,338,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001710,S00084,215,229,Alanine aminotransferase increased,Investigations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001711,S00084,571,586,Aspartate aminotransferase increased,Investigations,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0001712,S00084,700,725,Hypotension,Vascular disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0001713,S00084,379,382,Fatigue,General disorders,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001714,S00084,84,112,Bilirubin increased,Investigations,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001715,S00084,16,38,Seizure,Nervous system disorders,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001716,S00084,5,6,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001717,S00084,16,30,Complement activation,Immune system disorders,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001718,S00085,276,291,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001719,S00085,103,119,Fatigue,General disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001720,S00085,146,156,Headache,Nervous system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0001721,S00085,96,114,Cough,"Respiratory, thoracic, mediastinal",2,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0001722,S00085,663,685,Tremor,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001723,S00085,512,521,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001724,S00085,117,122,Headache,Nervous system disorders,2,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0001725,S00085,532,538,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001726,S00085,574,600,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001727,S00086,415,416,Thrombocytopenia,Blood and lymphatic system,1,N,Y,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0001728,S00086,339,349,Sepsis,Infections and infestations,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001729,S00086,565,574,Cytomegalovirus infection,Infections and infestations,3,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0001730,S00086,706,715,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001731,S00086,462,476,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001732,S00086,393,411,Hypotension,Vascular disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001733,S00086,573,597,Nausea,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001734,S00086,301,320,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001735,S00086,679,705,Vomiting,Gastrointestinal disorders,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001736,S00086,708,728,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001737,S00086,205,231,Vomiting,Gastrointestinal disorders,4,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001738,S00086,431,456,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001739,S00086,216,243,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001740,S00086,577,595,Fatigue,General disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001741,S00086,459,485,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001742,S00086,702,728,Anaemia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001743,S00087,3,7,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0001744,S00087,655,657,Mucosal inflammation,Gastrointestinal disorders,3,Y,N,None,Not recovered,N,0,N,0,N,N,N
AE0001745,S00087,208,229,Neutropenia,Blood and lymphatic system,3,Y,N,None,Recovering,N,0,N,0,N,N,N
AE0001746,S00087,490,491,Nausea,Gastrointestinal disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0001747,S00087,172,179,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001748,S00087,77,97,Aphasia,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001749,S00087,13,42,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001750,S00087,56,59,Pyrexia,General disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001751,S00087,246,263,Complement activation,Immune system disorders,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001752,S00087,152,168,Aphasia,Nervous system disorders,4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001753,S00087,123,150,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0001754,S00087,212,218,Fatigue,General disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001755,S00087,237,261,Bilirubin increased,Investigations,2,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0001756,S00087,374,399,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0001757,S00087,634,657,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001758,S00087,589,610,Cytomegalovirus infection,Infections and infestations,5,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001759,S00087,536,537,Diarrhoea,Gastrointestinal disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001760,S00087,128,135,Fatigue,General disorders,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001761,S00087,643,650,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0001762,S00087,112,137,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001763,S00087,87,99,Fatigue,General disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001764,S00087,58,83,Headache,Nervous system disorders,2,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0001765,S00087,659,666,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001766,S00087,372,396,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0001767,S00089,10,26,Neutropenia,Blood and lymphatic system,3,Y,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001768,S00089,493,503,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001769,S00089,57,71,Sepsis,Infections and infestations,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001770,S00089,520,533,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001771,S00089,22,28,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001772,S00089,288,296,Tachycardia,Cardiac disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001773,S00089,677,686,Sepsis,Infections and infestations,5,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001774,S00089,404,407,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0001775,S00089,483,492,Sepsis,Infections and infestations,5,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0001776,S00089,456,481,Alanine aminotransferase increased,Investigations,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001777,S00089,649,675,Confusional state,Psychiatric disorders,2,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0001778,S00089,125,140,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001779,S00091,392,421,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001780,S00091,49,62,Headache,Nervous system disorders,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0001781,S00091,292,293,Tachycardia,Cardiac disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0001782,S00091,723,740,Aspartate aminotransferase increased,Investigations,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001783,S00091,194,200,Anaemia,Blood and lymphatic system,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001784,S00091,86,98,Complement activation,Immune system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001785,S00091,508,520,Thrombocytopenia,Blood and lymphatic system,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001786,S00091,726,751,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001787,S00091,486,490,Tremor,Nervous system disorders,4,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0001788,S00091,416,420,Nausea,Gastrointestinal disorders,3,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0001789,S00091,235,244,Hypogammaglobulinaemia,Immune system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001790,S00091,675,689,Hypotension,Vascular disorders,4,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001791,S00091,207,222,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0001792,S00091,312,332,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001793,S00092,1,5,Cytokine release syndrome,Immune system disorders,4,Y,Y,Tocilizumab,Recovered with sequelae,Y,4,N,0,N,N,Y
AE0001794,S00092,9,22,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0001795,S00092,361,365,Aphasia,Nervous system disorders,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001796,S00092,126,136,Anaemia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001797,S00092,603,629,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001798,S00092,343,364,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001799,S00092,360,385,Complement activation,Immune system disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0001800,S00092,156,168,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001801,S00092,287,294,Seizure,Nervous system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001802,S00092,531,546,Aspartate aminotransferase increased,Investigations,1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0001803,S00092,2,10,Tremor,Nervous system disorders,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0001804,S00092,275,302,Thrombocytopenia,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001805,S00092,673,676,Infusion related reaction,"Injury, poisoning, procedural",5,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0001806,S00092,625,628,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001807,S00092,646,675,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001808,S00092,687,695,Sepsis,Infections and infestations,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001809,S00092,66,70,Hypogammaglobulinaemia,Immune system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001810,S00092,286,311,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0001811,S00092,301,318,Cough,"Respiratory, thoracic, mediastinal",4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001812,S00092,326,335,Headache,Nervous system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001813,S00092,491,508,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001814,S00092,601,614,Confusional state,Psychiatric disorders,3,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0001815,S00094,514,542,Neutropenia,Blood and lymphatic system,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001816,S00094,467,469,Hypotension,Vascular disorders,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001817,S00094,29,48,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0001818,S00094,287,293,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001819,S00094,586,607,Nausea,Gastrointestinal disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001820,S00094,721,748,Neutropenia,Blood and lymphatic system,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0001821,S00094,370,399,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001822,S00094,216,236,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001823,S00094,102,116,Thrombocytopenia,Blood and lymphatic system,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0001824,S00094,266,280,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Dose modification,Fatal,N,0,N,0,N,N,N
AE0001825,S00094,589,591,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001826,S00094,501,507,Alanine aminotransferase increased,Investigations,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001827,S00094,444,459,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001828,S00094,14,19,Bilirubin increased,Investigations,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001829,S00094,18,45,Diarrhoea,Gastrointestinal disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001830,S00094,250,274,Fatigue,General disorders,3,N,Y,Drug interrupted,Fatal,N,0,N,0,N,N,N
AE0001831,S00094,334,335,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0001832,S00094,49,51,Aphasia,Nervous system disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001833,S00094,425,445,Aphasia,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001834,S00094,277,290,Neutropenia,Blood and lymphatic system,2,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0001835,S00094,334,344,Complement activation,Immune system disorders,1,N,N,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0001836,S00094,331,332,Tachycardia,Cardiac disorders,4,N,N,None,Unknown,N,0,N,0,N,N,N
AE0001837,S00094,251,254,Seizure,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001838,S00094,50,53,Aphasia,Nervous system disorders,4,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001839,S00095,552,562,Fatigue,General disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001840,S00095,654,666,Complement activation,Immune system disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0001841,S00095,72,76,Tachycardia,Cardiac disorders,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001842,S00095,596,618,Alanine aminotransferase increased,Investigations,3,Y,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001843,S00095,256,262,Tremor,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001844,S00095,568,569,Confusional state,Psychiatric disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001845,S00095,15,25,Headache,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001846,S00095,298,312,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001847,S00095,252,281,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001848,S00095,238,263,Cytomegalovirus infection,Infections and infestations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001849,S00095,81,91,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001850,S00095,45,54,Anaemia,Blood and lymphatic system,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0001851,S00095,73,80,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001852,S00095,525,549,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001853,S00095,239,256,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001854,S00095,122,136,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001855,S00096,370,391,Alanine aminotransferase increased,Investigations,4,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001856,S00096,314,322,Seizure,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001857,S00096,598,621,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001858,S00096,348,351,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001859,S00096,63,77,Fatigue,General disorders,3,Y,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001860,S00096,185,193,Alanine aminotransferase increased,Investigations,3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001861,S00096,142,164,Hypoxia,"Respiratory, thoracic, mediastinal",3,Y,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0001862,S00096,599,609,Neutropenia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001863,S00096,301,312,Nausea,Gastrointestinal disorders,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001864,S00096,350,366,Sepsis,Infections and infestations,5,N,Y,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0001865,S00096,657,663,Anaemia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001866,S00096,719,728,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001867,S00096,189,197,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0001868,S00096,313,324,Complement activation,Immune system disorders,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001869,S00096,620,628,Pyrexia,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001870,S00096,472,486,Anaemia,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001871,S00096,555,570,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001872,S00096,365,368,Seizure,Nervous system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001873,S00096,635,642,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001874,S00096,722,727,Bilirubin increased,Investigations,4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001875,S00096,359,366,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0001876,S00096,173,196,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001877,S00096,37,51,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001878,S00096,677,691,Vomiting,Gastrointestinal disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001879,S00096,49,51,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001880,S00096,162,191,Pyrexia,General disorders,2,N,N,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0001881,S00096,436,457,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001882,S00096,43,72,Headache,Nervous system disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0001883,S00096,79,96,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0001884,S00096,61,71,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001885,S00096,275,300,Tachycardia,Cardiac disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001886,S00096,269,271,Anaemia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001887,S00096,60,70,Aphasia,Nervous system disorders,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001888,S00096,388,392,Hypotension,Vascular disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001889,S00096,407,436,Fatigue,General disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001890,S00096,36,51,Anaemia,Blood and lymphatic system,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0001891,S00096,703,728,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001892,S00096,464,490,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001893,S00096,677,704,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001894,S00096,647,653,Nausea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0001895,S00096,357,360,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001896,S00096,529,542,Nausea,Gastrointestinal disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001897,S00097,391,414,Diarrhoea,Gastrointestinal disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001898,S00097,688,691,Cough,"Respiratory, thoracic, mediastinal",2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001899,S00097,49,58,Diarrhoea,Gastrointestinal disorders,1,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0001900,S00097,67,84,Thrombocytopenia,Blood and lymphatic system,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001901,S00097,142,144,Aspartate aminotransferase increased,Investigations,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001902,S00097,659,688,Neutropenia,Blood and lymphatic system,3,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0001903,S00097,273,279,Diarrhoea,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001904,S00097,394,413,Sepsis,Infections and infestations,2,N,Y,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0001905,S00097,263,271,Tachycardia,Cardiac disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001906,S00097,393,404,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001907,S00097,195,216,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0001908,S00097,233,261,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001909,S00097,636,662,Hypogammaglobulinaemia,Immune system disorders,4,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0001910,S00097,291,299,Aphasia,Nervous system disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001911,S00097,717,730,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001912,S00097,123,143,Confusional state,Psychiatric disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001913,S00097,450,458,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001914,S00097,708,710,Hypotension,Vascular disorders,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0001915,S00097,499,521,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001916,S00098,537,548,Hypotension,Vascular disorders,1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0001917,S00098,687,696,Nausea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001918,S00098,466,485,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001919,S00098,496,507,Tremor,Nervous system disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0001920,S00098,263,269,Cytomegalovirus infection,Infections and infestations,5,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001921,S00098,332,356,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001922,S00098,660,677,Sepsis,Infections and infestations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001923,S00099,441,442,Tremor,Nervous system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0001924,S00099,46,75,Fatigue,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001925,S00099,390,406,Neutropenia,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001926,S00099,398,399,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0001927,S00099,238,262,Tachycardia,Cardiac disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0001928,S00099,94,103,Seizure,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001929,S00099,360,368,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001930,S00099,602,605,Bilirubin increased,Investigations,1,N,Y,Dose modification,Unknown,N,0,N,0,N,N,N
AE0001931,S00099,59,85,Hypotension,Vascular disorders,2,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0001932,S00099,725,733,Confusional state,Psychiatric disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001933,S00100,345,363,Aphasia,Nervous system disorders,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001934,S00100,691,702,Hypotension,Vascular disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001935,S00100,415,442,Seizure,Nervous system disorders,3,Y,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0001936,S00100,42,65,Complement activation,Immune system disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0001937,S00100,36,51,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0001938,S00100,5,13,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001939,S00100,500,519,Diarrhoea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001940,S00100,10,28,Diarrhoea,Gastrointestinal disorders,4,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0001941,S00100,544,549,Hypogammaglobulinaemia,Immune system disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001942,S00100,699,726,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0001943,S00100,81,93,Tremor,Nervous system disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0001944,S00100,641,670,Vomiting,Gastrointestinal disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0001945,S00100,193,206,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001946,S00100,452,469,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001947,S00100,369,385,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001948,S00100,488,497,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0001949,S00100,66,71,Complement activation,Immune system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001950,S00100,218,223,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001951,S00100,655,669,Tremor,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001952,S00100,297,298,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001953,S00101,2,5,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0001954,S00101,689,699,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001955,S00101,503,527,Seizure,Nervous system disorders,4,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0001956,S00101,199,205,Sepsis,Infections and infestations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001957,S00101,379,385,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001958,S00101,713,728,Tremor,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001959,S00101,329,340,Aphasia,Nervous system disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001960,S00101,288,296,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001961,S00101,608,626,Hypotension,Vascular disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001962,S00101,322,342,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001963,S00101,286,295,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Recovering,N,0,N,0,N,Y,Y
AE0001964,S00101,720,738,Seizure,Nervous system disorders,4,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001965,S00101,556,580,Tremor,Nervous system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001966,S00101,423,436,Seizure,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001967,S00101,125,151,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001968,S00101,466,472,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001969,S00101,665,693,Infusion related reaction,"Injury, poisoning, procedural",5,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001970,S00101,622,645,Neutropenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001971,S00101,307,325,Aphasia,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001972,S00101,638,649,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0001973,S00101,700,714,Pyrexia,General disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001974,S00101,304,330,Vomiting,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001975,S00101,248,272,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001976,S00101,428,451,Tremor,Nervous system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0001977,S00101,683,684,Sepsis,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001978,S00101,415,436,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001979,S00101,17,35,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0001980,S00101,69,75,Sepsis,Infections and infestations,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001981,S00102,247,270,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001982,S00102,264,284,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001983,S00102,264,279,Diarrhoea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001984,S00102,371,384,Headache,Nervous system disorders,1,N,Y,Drug interrupted,Fatal,N,0,N,0,N,N,N
AE0001985,S00102,543,547,Headache,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001986,S00102,316,339,Pyrexia,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0001987,S00102,69,93,Aspartate aminotransferase increased,Investigations,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0001988,S00102,540,547,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001989,S00102,680,686,Nausea,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0001990,S00102,127,145,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001991,S00102,72,99,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0001992,S00102,1,2,Aphasia,Nervous system disorders,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0001993,S00102,234,249,Bilirubin increased,Investigations,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0001994,S00102,28,51,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Concomitant medication,Fatal,N,0,N,0,N,Y,Y
AE0001995,S00102,145,164,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0001996,S00102,503,521,Thrombocytopenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0001997,S00102,413,428,Cough,"Respiratory, thoracic, mediastinal",3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001998,S00102,61,70,Aphasia,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0001999,S00102,312,341,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002000,S00102,556,578,Aphasia,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002001,S00102,222,247,Tachycardia,Cardiac disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002002,S00102,131,154,Alanine aminotransferase increased,Investigations,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002003,S00102,621,648,Tremor,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002004,S00102,591,597,Hypotension,Vascular disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002005,S00102,560,565,Tachycardia,Cardiac disorders,1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0002006,S00102,353,368,Infusion related reaction,"Injury, poisoning, procedural",4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002007,S00102,339,340,Aspartate aminotransferase increased,Investigations,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0002008,S00102,250,263,Pyrexia,General disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002009,S00102,91,107,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002010,S00103,674,677,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002011,S00103,488,489,Hypoxia,"Respiratory, thoracic, mediastinal",4,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0002012,S00103,623,647,Diarrhoea,Gastrointestinal disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002013,S00103,570,593,Sepsis,Infections and infestations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002014,S00103,24,48,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002015,S00103,726,741,Bilirubin increased,Investigations,3,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0002016,S00103,387,403,Aphasia,Nervous system disorders,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002017,S00103,351,379,Sepsis,Infections and infestations,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0002018,S00103,280,290,Hypotension,Vascular disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002019,S00103,712,720,Sepsis,Infections and infestations,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002020,S00103,493,511,Hypogammaglobulinaemia,Immune system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002021,S00103,339,367,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002022,S00103,621,648,Aspartate aminotransferase increased,Investigations,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002023,S00103,250,253,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002024,S00103,175,199,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002025,S00103,129,142,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,Hospitalization,Recovered,N,0,N,0,N,Y,Y
AE0002026,S00103,725,753,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0002027,S00103,517,546,Vomiting,Gastrointestinal disorders,1,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0002028,S00103,439,455,Seizure,Nervous system disorders,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002029,S00103,4,14,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002030,S00103,264,290,Tachycardia,Cardiac disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002031,S00103,589,610,Vomiting,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002032,S00104,701,714,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002033,S00104,581,601,Fatigue,General disorders,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0002034,S00104,642,669,Vomiting,Gastrointestinal disorders,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0002035,S00104,227,237,Tachycardia,Cardiac disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002036,S00104,341,352,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002037,S00104,58,76,Aphasia,Nervous system disorders,2,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0002038,S00104,656,662,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002039,S00104,131,147,Seizure,Nervous system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002040,S00104,53,69,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002041,S00104,627,656,Hypotension,Vascular disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002042,S00104,33,39,Cytomegalovirus infection,Infections and infestations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002043,S00104,267,275,Anaemia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002044,S00104,36,65,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002045,S00104,346,349,Anaemia,Blood and lymphatic system,3,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0002046,S00104,449,477,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0002047,S00105,6,19,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0002048,S00105,587,592,Anaemia,Blood and lymphatic system,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002049,S00105,367,379,Seizure,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002050,S00105,393,408,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002051,S00105,138,140,Neutropenia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002052,S00105,141,166,Tremor,Nervous system disorders,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002053,S00105,184,191,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0002054,S00105,687,710,Aspartate aminotransferase increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002055,S00105,340,352,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002056,S00105,426,443,Fatigue,General disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002057,S00105,300,312,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002058,S00105,297,310,Pyrexia,General disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002059,S00105,471,486,Confusional state,Psychiatric disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002060,S00105,63,71,Confusional state,Psychiatric disorders,4,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002061,S00105,653,670,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002062,S00105,414,434,Anaemia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002063,S00105,144,155,Complement activation,Immune system disorders,1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0002064,S00105,539,546,Complement activation,Immune system disorders,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002065,S00105,728,729,Seizure,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002066,S00105,704,713,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002067,S00105,416,438,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002068,S00106,1,16,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0002069,S00106,614,627,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0002070,S00106,422,428,Mucosal inflammation,Gastrointestinal disorders,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0002071,S00106,203,230,Headache,Nervous system disorders,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002072,S00106,444,468,Thrombotic microangiopathy,Blood and lymphatic system,3,Y,Y,Drug interrupted,Recovered,N,0,N,0,N,Y,Y
AE0002073,S00106,167,179,Nausea,Gastrointestinal disorders,4,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0002074,S00106,613,628,Aspartate aminotransferase increased,Investigations,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002075,S00106,465,487,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002076,S00106,40,57,Hypotension,Vascular disorders,3,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0002077,S00106,219,220,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002078,S00106,536,550,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002079,S00106,642,659,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002080,S00106,132,140,Cytomegalovirus infection,Infections and infestations,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002081,S00106,105,118,Aphasia,Nervous system disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002082,S00106,66,93,Fatigue,General disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002083,S00106,321,332,Vomiting,Gastrointestinal disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0002084,S00106,537,540,Aphasia,Nervous system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002085,S00106,146,172,Cytomegalovirus infection,Infections and infestations,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002086,S00106,659,676,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002087,S00106,644,662,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002088,S00106,226,250,Vomiting,Gastrointestinal disorders,2,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0002089,S00106,44,53,Anaemia,Blood and lymphatic system,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002090,S00107,592,613,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002091,S00107,411,414,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0002092,S00107,271,287,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002093,S00107,244,257,Confusional state,Psychiatric disorders,4,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0002094,S00107,709,711,Vomiting,Gastrointestinal disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002095,S00107,59,84,Aphasia,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002096,S00107,699,720,Infusion related reaction,"Injury, poisoning, procedural",4,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002097,S00107,286,301,Neutropenia,Blood and lymphatic system,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002098,S00107,627,637,Diarrhoea,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002099,S00108,453,461,Vomiting,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002100,S00108,298,301,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002101,S00108,34,50,Anaemia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002102,S00108,565,591,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002103,S00108,530,549,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002104,S00108,266,280,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002105,S00108,184,212,Thrombocytopenia,Blood and lymphatic system,2,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0002106,S00108,518,525,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002107,S00108,562,582,Pyrexia,General disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002108,S00108,182,190,Complement activation,Immune system disorders,3,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0002109,S00108,152,164,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002110,S00108,606,626,Complement activation,Immune system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002111,S00108,388,395,Fatigue,General disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002112,S00108,577,593,Fatigue,General disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002113,S00108,270,276,Aphasia,Nervous system disorders,4,N,N,Drug interrupted,Fatal,N,0,N,0,N,N,N
AE0002114,S00108,333,341,Tremor,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002115,S00108,619,642,Diarrhoea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002116,S00108,559,569,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002117,S00108,378,391,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002118,S00108,426,452,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002119,S00108,449,459,Anaemia,Blood and lymphatic system,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002120,S00108,388,395,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002121,S00108,168,193,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002122,S00108,222,234,Mucosal inflammation,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002123,S00108,473,499,Headache,Nervous system disorders,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002124,S00108,134,149,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002125,S00108,43,58,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002126,S00109,279,291,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002127,S00109,163,191,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002128,S00109,640,644,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002129,S00109,600,618,Hypotension,Vascular disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0002130,S00109,453,458,Tremor,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002131,S00109,67,87,Seizure,Nervous system disorders,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002132,S00109,476,484,Seizure,Nervous system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002133,S00109,260,281,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002134,S00109,418,428,Headache,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002135,S00110,3,15,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0002136,S00110,533,551,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002137,S00110,317,341,Aspartate aminotransferase increased,Investigations,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0002138,S00110,688,713,Nausea,Gastrointestinal disorders,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0002139,S00110,16,20,Seizure,Nervous system disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002140,S00110,468,493,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002141,S00110,622,646,Tremor,Nervous system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002142,S00110,465,466,Thrombocytopenia,Blood and lymphatic system,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0002143,S00110,446,447,Thrombocytopenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0002144,S00110,518,546,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002145,S00110,287,301,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002146,S00110,80,93,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002147,S00110,103,121,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002148,S00110,399,403,Vomiting,Gastrointestinal disorders,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002149,S00110,136,155,Tremor,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002150,S00110,469,475,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0002151,S00110,673,688,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002152,S00110,14,25,Aphasia,Nervous system disorders,3,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0002153,S00110,69,74,Nausea,Gastrointestinal disorders,2,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0002154,S00110,645,673,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002155,S00110,443,448,Seizure,Nervous system disorders,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002156,S00110,149,169,Aspartate aminotransferase increased,Investigations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002157,S00110,460,463,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002158,S00110,136,148,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002159,S00110,390,412,Thrombotic microangiopathy,Blood and lymphatic system,5,N,N,Drug interrupted,Recovered,N,0,N,0,N,Y,Y
AE0002160,S00110,73,81,Pyrexia,General disorders,3,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0002161,S00110,415,426,Fatigue,General disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002162,S00110,527,545,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002163,S00110,723,743,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002164,S00110,727,738,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002165,S00110,21,43,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0002166,S00110,58,74,Hypotension,Vascular disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002167,S00110,295,307,Complement activation,Immune system disorders,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002168,S00111,142,157,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002169,S00111,159,186,Bilirubin increased,Investigations,3,Y,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002170,S00111,194,214,Hypotension,Vascular disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002171,S00111,408,414,Fatigue,General disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002172,S00111,155,181,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002173,S00111,201,205,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0002174,S00111,150,179,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0002175,S00111,418,445,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002176,S00111,127,154,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0002177,S00111,450,469,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002178,S00111,399,425,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002179,S00112,235,238,Pyrexia,General disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002180,S00112,299,327,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002181,S00112,427,432,Vomiting,Gastrointestinal disorders,3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002182,S00112,220,239,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002183,S00112,260,271,Cytomegalovirus infection,Infections and infestations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002184,S00112,277,279,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002185,S00112,302,312,Nausea,Gastrointestinal disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002186,S00112,106,123,Mucosal inflammation,Gastrointestinal disorders,5,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0002187,S00112,343,361,Anaemia,Blood and lymphatic system,4,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002188,S00112,567,588,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002189,S00112,154,164,Sepsis,Infections and infestations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002190,S00112,80,86,Thrombocytopenia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002191,S00112,452,480,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002192,S00112,237,259,Neutropenia,Blood and lymphatic system,1,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0002193,S00112,645,669,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002194,S00112,570,588,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002195,S00112,477,499,Anaemia,Blood and lymphatic system,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002196,S00112,239,244,Complement activation,Immune system disorders,3,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0002197,S00112,230,237,Thrombocytopenia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002198,S00113,525,531,Cytomegalovirus infection,Infections and infestations,5,Y,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0002199,S00113,70,80,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Recovering,N,0,N,0,N,Y,Y
AE0002200,S00113,41,42,Anaemia,Blood and lymphatic system,3,Y,Y,None,Recovering,N,0,N,0,N,N,N
AE0002201,S00113,608,629,Aspartate aminotransferase increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002202,S00113,284,298,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002203,S00113,516,522,Aspartate aminotransferase increased,Investigations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002204,S00113,518,539,Anaemia,Blood and lymphatic system,2,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0002205,S00113,96,97,Confusional state,Psychiatric disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002206,S00113,320,343,Thrombocytopenia,Blood and lymphatic system,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002207,S00113,616,624,Complement activation,Immune system disorders,3,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0002208,S00113,486,495,Seizure,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002209,S00113,169,190,Bilirubin increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002210,S00113,577,602,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002211,S00113,165,181,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002212,S00113,272,284,Neutropenia,Blood and lymphatic system,5,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002213,S00113,518,522,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002214,S00113,668,680,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002215,S00113,179,181,Anaemia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002216,S00113,144,169,Fatigue,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002217,S00113,611,614,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002218,S00113,608,615,Tachycardia,Cardiac disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002219,S00113,54,70,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002220,S00113,554,572,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0002221,S00113,524,528,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002222,S00113,222,251,Aphasia,Nervous system disorders,5,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0002223,S00113,589,604,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Unknown,N,0,N,0,N,Y,Y
AE0002224,S00113,642,650,Thrombocytopenia,Blood and lymphatic system,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002225,S00113,105,119,Anaemia,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002226,S00113,597,606,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002227,S00114,704,709,Infusion related reaction,"Injury, poisoning, procedural",4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002228,S00114,238,252,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002229,S00114,173,194,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002230,S00114,524,531,Confusional state,Psychiatric disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002231,S00114,526,549,Fatigue,General disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002232,S00114,562,587,Fatigue,General disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002233,S00114,171,173,Alanine aminotransferase increased,Investigations,3,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0002234,S00114,475,500,Anaemia,Blood and lymphatic system,5,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002235,S00114,595,623,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0002236,S00115,118,132,Cough,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002237,S00115,345,357,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002238,S00115,260,279,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002239,S00115,131,132,Thrombocytopenia,Blood and lymphatic system,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002240,S00115,53,75,Tremor,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002241,S00115,552,554,Sepsis,Infections and infestations,4,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0002242,S00115,50,53,Tachycardia,Cardiac disorders,3,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0002243,S00115,376,385,Tremor,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002244,S00115,705,717,Mucosal inflammation,Gastrointestinal disorders,5,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0002245,S00115,482,486,Hypotension,Vascular disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002246,S00115,447,459,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002247,S00115,169,188,Headache,Nervous system disorders,2,N,Y,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0002248,S00115,713,738,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002249,S00115,591,606,Aspartate aminotransferase increased,Investigations,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002250,S00116,2,11,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0002251,S00116,226,242,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0002252,S00116,224,228,Diarrhoea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002253,S00116,75,89,Pyrexia,General disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002254,S00116,207,213,Anaemia,Blood and lymphatic system,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0002255,S00116,105,130,Hypogammaglobulinaemia,Immune system disorders,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002256,S00116,319,333,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002257,S00116,390,411,Anaemia,Blood and lymphatic system,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002258,S00116,108,133,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Not recovered,N,0,N,0,N,Y,Y
AE0002259,S00116,109,122,Seizure,Nervous system disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002260,S00116,27,41,Bilirubin increased,Investigations,3,N,N,Dose modification,Unknown,N,0,N,0,N,N,N
AE0002261,S00116,12,38,Mucosal inflammation,Gastrointestinal disorders,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002262,S00116,690,692,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002263,S00116,107,125,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0002264,S00116,649,652,Confusional state,Psychiatric disorders,3,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0002265,S00116,542,557,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002266,S00116,413,421,Tachycardia,Cardiac disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0002267,S00116,444,451,Neutropenia,Blood and lymphatic system,4,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0002268,S00116,393,404,Complement activation,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002269,S00116,631,635,Hypotension,Vascular disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002270,S00116,510,514,Confusional state,Psychiatric disorders,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002271,S00116,576,581,Nausea,Gastrointestinal disorders,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002272,S00116,544,567,Cytomegalovirus infection,Infections and infestations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002273,S00116,187,196,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002274,S00116,232,260,Aphasia,Nervous system disorders,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002275,S00116,403,410,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0002276,S00116,382,398,Diarrhoea,Gastrointestinal disorders,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002277,S00116,126,151,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002278,S00116,154,175,Thrombocytopenia,Blood and lymphatic system,2,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0002279,S00116,606,631,Vomiting,Gastrointestinal disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0002280,S00116,702,712,Aphasia,Nervous system disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002281,S00116,84,88,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002282,S00116,703,712,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002283,S00116,531,539,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002284,S00117,1,9,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0002285,S00117,675,695,Fatigue,General disorders,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002286,S00117,26,40,Alanine aminotransferase increased,Investigations,3,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0002287,S00117,102,110,Diarrhoea,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002288,S00117,496,511,Thrombocytopenia,Blood and lymphatic system,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002289,S00117,9,16,Hypotension,Vascular disorders,3,Y,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0002290,S00117,57,73,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002291,S00117,59,68,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0002292,S00117,133,136,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002293,S00117,259,278,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002294,S00117,503,532,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002295,S00117,696,703,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002296,S00117,33,43,Bilirubin increased,Investigations,2,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0002297,S00117,104,111,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002298,S00117,565,589,Aphasia,Nervous system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002299,S00117,12,20,Confusional state,Psychiatric disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002300,S00117,622,629,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002301,S00117,386,400,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Recovering,N,0,N,0,N,Y,Y
AE0002302,S00117,494,496,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002303,S00117,352,377,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0002304,S00117,51,67,Hypogammaglobulinaemia,Immune system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002305,S00117,477,503,Diarrhoea,Gastrointestinal disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002306,S00117,228,253,Fatigue,General disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002307,S00117,524,547,Vomiting,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002308,S00117,679,704,Neutropenia,Blood and lymphatic system,3,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002309,S00117,134,151,Aphasia,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002310,S00117,39,52,Aphasia,Nervous system disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002311,S00117,194,205,Aspartate aminotransferase increased,Investigations,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002312,S00117,557,564,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002313,S00118,5,15,Cytokine release syndrome,Immune system disorders,4,Y,Y,Tocilizumab,Recovered with sequelae,Y,4,N,0,N,N,Y
AE0002314,S00118,539,563,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002315,S00118,377,385,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002316,S00118,38,65,Fatigue,General disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002317,S00118,137,165,Bilirubin increased,Investigations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002318,S00118,84,97,Sepsis,Infections and infestations,4,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002319,S00118,100,119,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002320,S00118,26,48,Aspartate aminotransferase increased,Investigations,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002321,S00118,725,747,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002322,S00118,187,216,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0002323,S00118,557,569,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002324,S00118,612,618,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0002325,S00118,119,123,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002326,S00118,668,677,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002327,S00118,546,556,Complement activation,Immune system disorders,5,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0002328,S00118,420,449,Fatigue,General disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002329,S00118,216,233,Tremor,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002330,S00118,597,604,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002331,S00118,237,243,Thrombocytopenia,Blood and lymphatic system,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0002332,S00118,348,357,Tremor,Nervous system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002333,S00118,196,208,Headache,Nervous system disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002334,S00118,603,618,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002335,S00118,245,268,Alanine aminotransferase increased,Investigations,4,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002336,S00118,568,597,Hypotension,Vascular disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002337,S00119,45,64,Hepatocellular injury,Hepatobiliary disorders,3,Y,Y,Tocilizumab,Recovered,Y,0,N,0,Y,N,Y
AE0002338,S00119,705,729,Confusional state,Psychiatric disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002339,S00119,168,173,Hypotension,Vascular disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002340,S00119,535,549,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002341,S00119,62,65,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002342,S00119,435,447,Headache,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002343,S00119,125,137,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002344,S00119,72,77,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002345,S00120,515,532,Complement activation,Immune system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002346,S00120,141,146,Confusional state,Psychiatric disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002347,S00120,12,14,Seizure,Nervous system disorders,1,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0002348,S00120,329,335,Aspartate aminotransferase increased,Investigations,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0002349,S00120,567,594,Seizure,Nervous system disorders,4,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0002350,S00120,651,678,Confusional state,Psychiatric disorders,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0002351,S00120,218,233,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002352,S00120,1,19,Confusional state,Psychiatric disorders,1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0002353,S00120,558,581,Seizure,Nervous system disorders,5,N,N,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0002354,S00120,280,301,Alanine aminotransferase increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002355,S00120,224,236,Headache,Nervous system disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0002356,S00120,287,293,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002357,S00120,515,516,Hypogammaglobulinaemia,Immune system disorders,3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002358,S00120,125,145,Sepsis,Infections and infestations,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002359,S00120,175,176,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002360,S00120,166,168,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002361,S00120,362,372,Pyrexia,General disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002362,S00121,643,652,Aspartate aminotransferase increased,Investigations,4,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0002363,S00121,422,451,Hypotension,Vascular disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002364,S00121,332,359,Hypogammaglobulinaemia,Immune system disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0002365,S00121,115,130,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002366,S00121,570,598,Tachycardia,Cardiac disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002367,S00121,204,210,Thrombocytopenia,Blood and lymphatic system,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002368,S00121,154,160,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002369,S00121,203,218,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002370,S00121,535,545,Bilirubin increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002371,S00121,313,315,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002372,S00122,7,9,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0002373,S00122,11,25,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0002374,S00122,343,352,Pyrexia,General disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002375,S00122,634,660,Cough,"Respiratory, thoracic, mediastinal",3,Y,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002376,S00122,285,313,Neutropenia,Blood and lymphatic system,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002377,S00122,160,185,Aphasia,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002378,S00122,290,303,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002379,S00122,212,234,Complement activation,Immune system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0002380,S00122,478,481,Seizure,Nervous system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0002381,S00122,328,353,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002382,S00122,47,52,Confusional state,Psychiatric disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002383,S00122,371,386,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002384,S00122,227,242,Tremor,Nervous system disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002385,S00122,629,645,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002386,S00122,152,154,Nausea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002387,S00122,533,551,Fatigue,General disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002388,S00122,608,620,Seizure,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002389,S00122,29,42,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002390,S00122,103,109,Anaemia,Blood and lymphatic system,1,N,N,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0002391,S00122,501,509,Aphasia,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002392,S00122,525,541,Fatigue,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002393,S00122,49,75,Alanine aminotransferase increased,Investigations,1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0002394,S00122,333,336,Alanine aminotransferase increased,Investigations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002395,S00122,295,319,Sepsis,Infections and infestations,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002396,S00122,572,588,Tremor,Nervous system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002397,S00123,534,552,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002398,S00123,81,95,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002399,S00123,583,598,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,Drug interrupted,Recovered,N,0,N,0,N,Y,Y
AE0002400,S00123,614,629,Confusional state,Psychiatric disorders,5,N,N,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0002401,S00123,425,443,Neutropenia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002402,S00123,146,151,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002403,S00123,239,242,Complement activation,Immune system disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0002404,S00123,499,516,Neutropenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002405,S00123,579,582,Hypotension,Vascular disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002406,S00123,74,88,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002407,S00123,662,673,Fatigue,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002408,S00124,64,82,Hepatocellular injury,Hepatobiliary disorders,4,Y,Y,Tocilizumab,Recovered,Y,0,N,0,Y,N,Y
AE0002409,S00124,153,174,Bilirubin increased,Investigations,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002410,S00124,36,54,Sepsis,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002411,S00124,563,577,Pyrexia,General disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0002412,S00124,194,212,Pyrexia,General disorders,1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0002413,S00124,229,246,Anaemia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002414,S00124,42,58,Bilirubin increased,Investigations,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002415,S00124,592,611,Pyrexia,General disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002416,S00124,258,278,Confusional state,Psychiatric disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002417,S00124,158,186,Confusional state,Psychiatric disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002418,S00124,96,108,Aspartate aminotransferase increased,Investigations,2,N,N,None,Fatal,N,0,N,0,N,N,N
AE0002419,S00124,579,600,Pyrexia,General disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0002420,S00124,420,422,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,Dose modification,Recovered,N,0,N,0,N,Y,Y
AE0002421,S00124,657,670,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002422,S00124,588,602,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,Hospitalization,Recovered,N,0,N,0,N,Y,Y
AE0002423,S00124,314,324,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0002424,S00124,424,435,Hypotension,Vascular disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002425,S00124,607,630,Seizure,Nervous system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002426,S00125,227,238,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0002427,S00125,373,401,Diarrhoea,Gastrointestinal disorders,3,Y,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002428,S00125,385,386,Complement activation,Immune system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002429,S00125,511,532,Sepsis,Infections and infestations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002430,S00125,238,244,Tachycardia,Cardiac disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002431,S00125,376,386,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002432,S00125,683,699,Fatigue,General disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002433,S00125,635,662,Pyrexia,General disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002434,S00125,606,634,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002435,S00125,339,358,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002436,S00125,68,80,Bilirubin increased,Investigations,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002437,S00125,210,213,Cytomegalovirus infection,Infections and infestations,1,N,N,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0002438,S00125,624,631,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002439,S00125,44,60,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002440,S00125,106,107,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002441,S00125,365,385,Tremor,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002442,S00126,669,678,Vomiting,Gastrointestinal disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0002443,S00126,112,119,Vomiting,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002444,S00126,278,280,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002445,S00126,52,77,Aspartate aminotransferase increased,Investigations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002446,S00126,1,9,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,Dose modification,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0002447,S00126,179,196,Alanine aminotransferase increased,Investigations,1,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0002448,S00126,360,382,Bilirubin increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002449,S00126,303,325,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002450,S00126,24,25,Confusional state,Psychiatric disorders,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002451,S00126,45,68,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0002452,S00126,518,521,Tachycardia,Cardiac disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0002453,S00126,721,729,Aphasia,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002454,S00126,97,98,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002455,S00126,331,352,Thrombocytopenia,Blood and lymphatic system,3,N,N,None,Unknown,N,0,N,0,N,N,N
AE0002456,S00127,453,460,Neutropenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002457,S00127,30,31,Alanine aminotransferase increased,Investigations,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0002458,S00127,516,537,Mucosal inflammation,Gastrointestinal disorders,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0002459,S00127,103,118,Aphasia,Nervous system disorders,3,Y,N,None,Unknown,N,0,N,0,N,N,N
AE0002460,S00127,589,609,Vomiting,Gastrointestinal disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002461,S00127,141,155,Tachycardia,Cardiac disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002462,S00127,442,454,Fatigue,General disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002463,S00127,379,407,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002464,S00127,399,422,Hypotension,Vascular disorders,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002465,S00127,656,668,Tachycardia,Cardiac disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002466,S00127,465,466,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002467,S00127,80,103,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002468,S00127,548,560,Alanine aminotransferase increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002469,S00127,186,206,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002470,S00127,551,559,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0002471,S00127,518,520,Anaemia,Blood and lymphatic system,2,N,N,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0002472,S00127,544,547,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002473,S00127,506,523,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002474,S00127,414,430,Anaemia,Blood and lymphatic system,1,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0002475,S00127,397,413,Seizure,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002476,S00127,148,155,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002477,S00127,321,348,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002478,S00127,299,321,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002479,S00127,67,91,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002480,S00128,29,33,Seizure,Nervous system disorders,1,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0002481,S00128,334,338,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002482,S00128,120,146,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002483,S00128,624,637,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002484,S00128,689,697,Hypotension,Vascular disorders,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0002485,S00128,371,399,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002486,S00128,13,40,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002487,S00128,147,157,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002488,S00128,317,340,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002489,S00128,606,631,Confusional state,Psychiatric disorders,3,N,N,None,Unknown,N,0,N,0,N,N,N
AE0002490,S00128,384,398,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0002491,S00128,635,647,Diarrhoea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0002492,S00128,86,97,Tachycardia,Cardiac disorders,2,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0002493,S00128,570,584,Neutropenia,Blood and lymphatic system,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002494,S00130,535,540,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002495,S00130,453,482,Anaemia,Blood and lymphatic system,1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0002496,S00130,649,651,Aspartate aminotransferase increased,Investigations,4,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0002497,S00131,519,548,Bilirubin increased,Investigations,1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0002498,S00131,261,282,Headache,Nervous system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002499,S00131,322,345,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002500,S00131,152,156,Seizure,Nervous system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002501,S00131,536,539,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002502,S00131,534,560,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002503,S00131,198,214,Pyrexia,General disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0002504,S00131,581,606,Neutropenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002505,S00131,218,239,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002506,S00131,602,606,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002507,S00131,60,66,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002508,S00132,1,3,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0002509,S00132,168,177,Mucosal inflammation,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002510,S00132,688,707,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002511,S00132,338,348,Hypotension,Vascular disorders,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0002512,S00132,182,208,Tremor,Nervous system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002513,S00132,362,369,Thrombocytopenia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002514,S00132,99,123,Sepsis,Infections and infestations,3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002515,S00132,339,342,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002516,S00132,209,220,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002517,S00132,561,581,Aspartate aminotransferase increased,Investigations,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0002518,S00132,536,545,Bilirubin increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002519,S00132,641,652,Diarrhoea,Gastrointestinal disorders,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0002520,S00132,403,409,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0002521,S00132,178,181,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002522,S00132,650,672,Sepsis,Infections and infestations,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002523,S00132,600,615,Seizure,Nervous system disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002524,S00132,525,527,Hypotension,Vascular disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002525,S00132,450,476,Headache,Nervous system disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0002526,S00132,528,540,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002527,S00132,405,432,Aspartate aminotransferase increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002528,S00132,681,684,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002529,S00132,256,259,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002530,S00132,418,427,Hypogammaglobulinaemia,Immune system disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002531,S00132,592,596,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0002532,S00132,12,30,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002533,S00133,64,90,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002534,S00133,575,593,Neutropenia,Blood and lymphatic system,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002535,S00133,313,324,Thrombocytopenia,Blood and lymphatic system,5,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002536,S00134,576,590,Infusion related reaction,"Injury, poisoning, procedural",4,Y,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002537,S00134,302,330,Anaemia,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002538,S00134,686,710,Nausea,Gastrointestinal disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0002539,S00134,227,230,Cytomegalovirus infection,Infections and infestations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002540,S00134,257,264,Alanine aminotransferase increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002541,S00134,487,504,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002542,S00134,440,463,Thrombocytopenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002543,S00134,197,207,Thrombocytopenia,Blood and lymphatic system,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002544,S00134,444,467,Headache,Nervous system disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0002545,S00134,164,184,Vomiting,Gastrointestinal disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0002546,S00134,185,199,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002547,S00134,717,742,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002548,S00134,547,551,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002549,S00134,432,434,Tremor,Nervous system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002550,S00134,648,664,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0002551,S00134,707,724,Bilirubin increased,Investigations,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002552,S00134,272,293,Hypogammaglobulinaemia,Immune system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002553,S00134,469,471,Seizure,Nervous system disorders,5,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002554,S00134,377,395,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002555,S00134,209,225,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002556,S00135,124,138,Seizure,Nervous system disorders,4,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002557,S00135,254,280,Hypotension,Vascular disorders,2,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0002558,S00135,244,258,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002559,S00135,317,335,Aspartate aminotransferase increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002560,S00135,102,115,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0002561,S00135,182,190,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0002562,S00135,286,313,Neutropenia,Blood and lymphatic system,5,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002563,S00135,707,725,Fatigue,General disorders,4,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002564,S00135,405,420,Complement activation,Immune system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002565,S00135,99,128,Aphasia,Nervous system disorders,4,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002566,S00135,147,152,Cough,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002567,S00135,214,232,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002568,S00137,103,112,Aphasia,Nervous system disorders,5,Y,Y,None,Unknown,N,0,N,0,N,N,N
AE0002569,S00137,432,445,Thrombocytopenia,Blood and lymphatic system,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0002570,S00137,87,90,Confusional state,Psychiatric disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002571,S00137,416,424,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002572,S00137,693,720,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Unknown,N,0,N,0,N,Y,Y
AE0002573,S00137,238,247,Aphasia,Nervous system disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002574,S00137,32,57,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002575,S00137,406,426,Complement activation,Immune system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002576,S00137,517,527,Sepsis,Infections and infestations,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002577,S00137,359,380,Cytomegalovirus infection,Infections and infestations,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002578,S00137,295,306,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002579,S00137,505,525,Pyrexia,General disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002580,S00137,543,572,Alanine aminotransferase increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002581,S00137,427,450,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0002582,S00137,631,644,Neutropenia,Blood and lymphatic system,5,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002583,S00138,148,169,Thrombocytopenia,Blood and lymphatic system,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002584,S00138,125,144,Nausea,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002585,S00138,176,196,Headache,Nervous system disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0002586,S00138,346,349,Thrombocytopenia,Blood and lymphatic system,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002587,S00138,673,695,Confusional state,Psychiatric disorders,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002588,S00138,532,555,Bilirubin increased,Investigations,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002589,S00138,294,311,Vomiting,Gastrointestinal disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002590,S00138,92,94,Sepsis,Infections and infestations,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002591,S00138,263,281,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002592,S00138,125,134,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002593,S00138,301,302,Aphasia,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002594,S00138,544,568,Cytomegalovirus infection,Infections and infestations,3,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0002595,S00138,376,377,Diarrhoea,Gastrointestinal disorders,1,N,N,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0002596,S00139,2,21,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0002597,S00139,295,320,Tremor,Nervous system disorders,2,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0002598,S00139,395,424,Tremor,Nervous system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002599,S00139,444,447,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002600,S00139,432,449,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002601,S00139,451,453,Alanine aminotransferase increased,Investigations,5,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002602,S00139,470,479,Hypotension,Vascular disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002603,S00139,696,721,Bilirubin increased,Investigations,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002604,S00139,349,373,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002605,S00139,716,732,Neutropenia,Blood and lymphatic system,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002606,S00139,408,415,Seizure,Nervous system disorders,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002607,S00139,690,706,Cytomegalovirus infection,Infections and infestations,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002608,S00139,397,398,Anaemia,Blood and lymphatic system,3,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0002609,S00139,63,88,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002610,S00139,538,557,Hypotension,Vascular disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002611,S00139,452,476,Seizure,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002612,S00139,57,86,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002613,S00139,278,280,Headache,Nervous system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002614,S00139,157,166,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002615,S00139,637,651,Anaemia,Blood and lymphatic system,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002616,S00139,574,586,Sepsis,Infections and infestations,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0002617,S00139,306,320,Complement activation,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002618,S00139,675,691,Bilirubin increased,Investigations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002619,S00139,529,535,Bilirubin increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002620,S00139,368,379,Complement activation,Immune system disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0002621,S00139,632,639,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002622,S00139,311,321,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002623,S00139,24,25,Hypotension,Vascular disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002624,S00139,74,85,Headache,Nervous system disorders,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0002625,S00141,533,536,Cough,"Respiratory, thoracic, mediastinal",3,Y,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0002626,S00141,234,244,Cytomegalovirus infection,Infections and infestations,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002627,S00141,320,344,Hypotension,Vascular disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002628,S00141,104,131,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002629,S00141,216,241,Fatigue,General disorders,2,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0002630,S00141,653,665,Aphasia,Nervous system disorders,2,N,Y,Hospitalization,Fatal,N,0,N,0,N,N,N
AE0002631,S00141,395,399,Headache,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002632,S00141,175,191,Cytomegalovirus infection,Infections and infestations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002633,S00141,713,735,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002634,S00142,729,747,Diarrhoea,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002635,S00142,287,302,Confusional state,Psychiatric disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002636,S00142,80,88,Pyrexia,General disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0002637,S00142,713,731,Seizure,Nervous system disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002638,S00142,501,514,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002639,S00142,497,523,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002640,S00142,226,249,Aspartate aminotransferase increased,Investigations,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002641,S00142,250,276,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002642,S00142,300,329,Fatigue,General disorders,4,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002643,S00142,686,706,Sepsis,Infections and infestations,1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0002644,S00142,357,365,Aspartate aminotransferase increased,Investigations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002645,S00142,586,610,Diarrhoea,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002646,S00142,386,413,Neutropenia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002647,S00142,124,127,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002648,S00142,77,84,Headache,Nervous system disorders,1,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0002649,S00142,588,604,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002650,S00142,350,355,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002651,S00143,1,20,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0002652,S00143,4,22,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,3,Y,Y,Corticosteroids,Recovered,N,0,Y,3,N,N,Y
AE0002653,S00143,678,707,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0002654,S00143,396,406,Hypotension,Vascular disorders,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0002655,S00143,144,155,Pyrexia,General disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0002656,S00143,610,634,Neutropenia,Blood and lymphatic system,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002657,S00143,441,461,Aspartate aminotransferase increased,Investigations,4,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0002658,S00143,372,394,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0002659,S00143,426,441,Fatigue,General disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002660,S00143,11,27,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002661,S00143,211,216,Confusional state,Psychiatric disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002662,S00143,14,25,Fatigue,General disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002663,S00143,674,703,Tachycardia,Cardiac disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002664,S00143,571,597,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002665,S00143,180,192,Nausea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002666,S00143,229,246,Cytomegalovirus infection,Infections and infestations,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002667,S00143,289,309,Headache,Nervous system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002668,S00143,346,363,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002669,S00143,381,394,Pyrexia,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002670,S00143,8,25,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002671,S00143,121,141,Alanine aminotransferase increased,Investigations,4,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002672,S00143,87,112,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002673,S00144,495,512,Fatigue,General disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002674,S00144,511,521,Cytomegalovirus infection,Infections and infestations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002675,S00144,676,689,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0002676,S00144,682,701,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002677,S00144,184,212,Seizure,Nervous system disorders,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0002678,S00144,539,549,Cough,"Respiratory, thoracic, mediastinal",3,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0002679,S00144,131,159,Cytomegalovirus infection,Infections and infestations,5,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002680,S00144,6,15,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002681,S00144,488,511,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002682,S00144,483,509,Confusional state,Psychiatric disorders,4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002683,S00144,325,326,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0002684,S00144,284,285,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002685,S00144,27,28,Complement activation,Immune system disorders,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0002686,S00144,26,45,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002687,S00144,188,192,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002688,S00144,28,54,Fatigue,General disorders,2,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0002689,S00146,348,349,Confusional state,Psychiatric disorders,1,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0002690,S00146,222,223,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002691,S00146,173,183,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002692,S00146,122,147,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002693,S00146,300,306,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002694,S00146,221,236,Cytomegalovirus infection,Infections and infestations,4,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0002695,S00146,505,528,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002696,S00146,327,334,Neutropenia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002697,S00146,479,482,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0002698,S00146,323,328,Nausea,Gastrointestinal disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002699,S00146,45,62,Thrombocytopenia,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002700,S00146,328,355,Headache,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002701,S00146,230,239,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002702,S00146,687,699,Alanine aminotransferase increased,Investigations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002703,S00146,682,693,Sepsis,Infections and infestations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002704,S00147,222,224,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002705,S00147,98,110,Hypoxia,"Respiratory, thoracic, mediastinal",3,Y,N,None,Not recovered,N,0,N,0,N,N,N
AE0002706,S00147,555,556,Neutropenia,Blood and lymphatic system,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002707,S00147,48,74,Cytomegalovirus infection,Infections and infestations,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0002708,S00147,293,313,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002709,S00147,571,595,Anaemia,Blood and lymphatic system,5,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002710,S00147,166,170,Anaemia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002711,S00147,501,516,Vomiting,Gastrointestinal disorders,2,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0002712,S00147,677,701,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002713,S00147,213,215,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002714,S00147,294,305,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0002715,S00147,287,308,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002716,S00147,723,727,Infusion related reaction,"Injury, poisoning, procedural",3,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0002717,S00147,172,199,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0002718,S00147,691,703,Aspartate aminotransferase increased,Investigations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002719,S00147,373,375,Sepsis,Infections and infestations,5,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002720,S00149,297,322,Hypotension,Vascular disorders,3,Y,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002721,S00149,409,423,Alanine aminotransferase increased,Investigations,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002722,S00149,19,32,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002723,S00149,375,383,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002724,S00149,473,485,Confusional state,Psychiatric disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0002725,S00149,403,430,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002726,S00149,519,529,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002727,S00149,28,44,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002728,S00149,481,510,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002729,S00149,202,212,Seizure,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002730,S00150,369,392,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0002731,S00150,216,239,Mucosal inflammation,Gastrointestinal disorders,5,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002732,S00150,572,573,Nausea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0002733,S00150,35,46,Nausea,Gastrointestinal disorders,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002734,S00150,250,266,Seizure,Nervous system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002735,S00150,261,273,Confusional state,Psychiatric disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002736,S00150,257,275,Seizure,Nervous system disorders,2,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0002737,S00150,238,260,Aphasia,Nervous system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002738,S00151,4,24,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0002739,S00151,571,596,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002740,S00151,627,649,Mucosal inflammation,Gastrointestinal disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0002741,S00151,629,631,Alanine aminotransferase increased,Investigations,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0002742,S00151,547,568,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002743,S00151,289,315,Fatigue,General disorders,2,N,Y,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0002744,S00151,561,584,Tachycardia,Cardiac disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002745,S00151,467,473,Vomiting,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0002746,S00151,673,678,Tachycardia,Cardiac disorders,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0002747,S00151,444,465,Pyrexia,General disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002748,S00151,337,338,Sepsis,Infections and infestations,5,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0002749,S00151,75,99,Alanine aminotransferase increased,Investigations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002750,S00151,138,158,Tremor,Nervous system disorders,3,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002751,S00151,139,152,Alanine aminotransferase increased,Investigations,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002752,S00151,602,630,Vomiting,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002753,S00151,453,475,Headache,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002754,S00151,593,611,Infusion related reaction,"Injury, poisoning, procedural",3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0002755,S00151,238,250,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002756,S00151,4,5,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002757,S00151,576,582,Sepsis,Infections and infestations,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002758,S00151,77,81,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002759,S00151,17,19,Tachycardia,Cardiac disorders,4,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002760,S00151,186,202,Cytomegalovirus infection,Infections and infestations,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002761,S00151,231,260,Thrombocytopenia,Blood and lymphatic system,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002762,S00151,448,468,Headache,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002763,S00151,139,145,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002764,S00152,474,495,Sepsis,Infections and infestations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002765,S00152,158,175,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002766,S00152,163,176,Cough,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002767,S00152,538,567,Diarrhoea,Gastrointestinal disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0002768,S00152,168,185,Confusional state,Psychiatric disorders,3,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0002769,S00152,539,556,Tachycardia,Cardiac disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002770,S00152,598,625,Complement activation,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002771,S00152,42,64,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0002772,S00152,357,365,Hypotension,Vascular disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002773,S00152,233,259,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0002774,S00152,642,671,Vomiting,Gastrointestinal disorders,1,N,N,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0002775,S00152,711,736,Mucosal inflammation,Gastrointestinal disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002776,S00152,367,394,Thrombocytopenia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002777,S00152,31,33,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002778,S00152,295,313,Anaemia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002779,S00152,482,484,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002780,S00152,709,711,Tremor,Nervous system disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0002781,S00152,297,307,Alanine aminotransferase increased,Investigations,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002782,S00152,174,175,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002783,S00152,203,218,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0002784,S00152,55,81,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002785,S00152,134,156,Aphasia,Nervous system disorders,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0002786,S00152,397,418,Seizure,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002787,S00152,338,339,Cough,"Respiratory, thoracic, mediastinal",4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002788,S00152,443,469,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002789,S00152,77,101,Hypogammaglobulinaemia,Immune system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002790,S00152,510,532,Anaemia,Blood and lymphatic system,2,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0002791,S00156,534,537,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0002792,S00156,295,301,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,Y,Y
AE0002793,S00156,423,444,Seizure,Nervous system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002794,S00156,551,573,Bilirubin increased,Investigations,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0002795,S00156,20,26,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0002796,S00156,577,593,Confusional state,Psychiatric disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002797,S00156,682,699,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0002798,S00156,44,73,Tremor,Nervous system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0002799,S00156,406,417,Alanine aminotransferase increased,Investigations,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002800,S00156,336,347,Headache,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002801,S00156,653,657,Anaemia,Blood and lymphatic system,3,N,N,None,Unknown,N,0,N,0,N,N,N
AE0002802,S00156,612,623,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002803,S00156,107,127,Nausea,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002804,S00156,329,347,Confusional state,Psychiatric disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002805,S00156,179,202,Headache,Nervous system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002806,S00156,559,578,Anaemia,Blood and lymphatic system,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002807,S00156,529,534,Confusional state,Psychiatric disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002808,S00156,288,290,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0002809,S00156,293,313,Seizure,Nervous system disorders,3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002810,S00156,379,383,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002811,S00156,113,116,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002812,S00156,454,481,Vomiting,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002813,S00156,205,215,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002814,S00156,15,44,Neutropenia,Blood and lymphatic system,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002815,S00156,426,430,Seizure,Nervous system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002816,S00156,665,673,Hypotension,Vascular disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002817,S00156,358,372,Sepsis,Infections and infestations,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002818,S00156,520,540,Aspartate aminotransferase increased,Investigations,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002819,S00156,306,327,Seizure,Nervous system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002820,S00156,76,105,Hypotension,Vascular disorders,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002821,S00157,581,595,Thrombocytopenia,Blood and lymphatic system,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002822,S00157,321,349,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002823,S00157,209,221,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002824,S00157,679,689,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002825,S00157,627,631,Fatigue,General disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002826,S00157,391,404,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002827,S00157,634,660,Fatigue,General disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002828,S00157,685,701,Anaemia,Blood and lymphatic system,3,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0002829,S00157,37,65,Anaemia,Blood and lymphatic system,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002830,S00157,543,551,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002831,S00157,690,697,Fatigue,General disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002832,S00157,311,317,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Recovering,N,0,N,0,N,Y,Y
AE0002833,S00157,188,192,Tremor,Nervous system disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0002834,S00157,388,404,Complement activation,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002835,S00157,452,461,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002836,S00157,271,286,Hypogammaglobulinaemia,Immune system disorders,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002837,S00157,221,239,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002838,S00157,611,631,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002839,S00157,728,757,Confusional state,Psychiatric disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002840,S00157,119,135,Thrombocytopenia,Blood and lymphatic system,3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002841,S00157,432,450,Nausea,Gastrointestinal disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002842,S00157,715,735,Anaemia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002843,S00157,606,633,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0002844,S00157,504,512,Hypotension,Vascular disorders,2,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0002845,S00157,611,631,Pyrexia,General disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002846,S00157,106,111,Anaemia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002847,S00158,3,9,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0002848,S00158,235,244,Neutropenia,Blood and lymphatic system,3,Y,N,None,Not recovered,N,0,N,0,N,N,N
AE0002849,S00158,300,303,Aspartate aminotransferase increased,Investigations,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002850,S00158,69,87,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002851,S00158,695,706,Thrombotic microangiopathy,Blood and lymphatic system,3,Y,Y,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0002852,S00158,628,631,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002853,S00158,432,453,Aspartate aminotransferase increased,Investigations,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0002854,S00158,558,570,Bilirubin increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002855,S00158,70,71,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0002856,S00158,258,275,Mucosal inflammation,Gastrointestinal disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0002857,S00158,353,355,Sepsis,Infections and infestations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002858,S00158,654,660,Pyrexia,General disorders,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002859,S00158,585,598,Tachycardia,Cardiac disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002860,S00158,34,42,Seizure,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002861,S00158,507,529,Thrombocytopenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002862,S00158,8,24,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002863,S00158,219,234,Fatigue,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002864,S00158,557,582,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Dose modification,Recovered,N,0,N,0,N,Y,Y
AE0002865,S00158,688,691,Tremor,Nervous system disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0002866,S00158,116,120,Pyrexia,General disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002867,S00158,206,216,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002868,S00158,494,501,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,Dose modification,Recovered,N,0,N,0,N,Y,Y
AE0002869,S00158,1,12,Fatigue,General disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002870,S00158,27,43,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002871,S00158,450,474,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002872,S00158,179,188,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002873,S00158,153,154,Headache,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002874,S00158,581,596,Bilirubin increased,Investigations,3,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0002875,S00158,587,600,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002876,S00158,709,727,Alanine aminotransferase increased,Investigations,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002877,S00158,31,40,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002878,S00158,404,420,Hypotension,Vascular disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002879,S00158,130,154,Nausea,Gastrointestinal disorders,3,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0002880,S00158,638,645,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002881,S00158,55,63,Hypogammaglobulinaemia,Immune system disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002882,S00158,701,726,Pyrexia,General disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002883,S00158,569,571,Mucosal inflammation,Gastrointestinal disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002884,S00159,5,13,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0002885,S00159,453,478,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002886,S00159,691,701,Anaemia,Blood and lymphatic system,4,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0002887,S00159,682,687,Thrombocytopenia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002888,S00159,175,184,Pyrexia,General disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0002889,S00159,340,365,Diarrhoea,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002890,S00159,139,163,Tremor,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002891,S00159,398,417,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002892,S00159,194,223,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002893,S00159,523,537,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002894,S00159,271,274,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0002895,S00159,444,464,Hypotension,Vascular disorders,1,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0002896,S00159,7,24,Pyrexia,General disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0002897,S00159,456,483,Thrombocytopenia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002898,S00159,368,376,Hypogammaglobulinaemia,Immune system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002899,S00159,74,90,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002900,S00159,131,150,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002901,S00159,631,658,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002902,S00159,294,305,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002903,S00159,332,349,Sepsis,Infections and infestations,5,N,Y,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0002904,S00159,725,734,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002905,S00160,1,9,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0002906,S00160,5,16,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,4,Y,Y,Corticosteroids,Recovered,N,0,Y,4,N,N,Y
AE0002907,S00160,331,341,Neutropenia,Blood and lymphatic system,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002908,S00160,649,658,Anaemia,Blood and lymphatic system,2,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0002909,S00160,726,731,Complement activation,Immune system disorders,2,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0002910,S00160,621,632,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002911,S00160,436,437,Headache,Nervous system disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002912,S00160,199,227,Thrombocytopenia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002913,S00160,356,375,Confusional state,Psychiatric disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002914,S00160,702,716,Alanine aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002915,S00160,435,441,Seizure,Nervous system disorders,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002916,S00160,613,626,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002917,S00160,353,364,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002918,S00160,672,701,Diarrhoea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002919,S00160,129,141,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002920,S00160,455,480,Fatigue,General disorders,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0002921,S00160,421,448,Tremor,Nervous system disorders,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0002922,S00160,612,615,Headache,Nervous system disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002923,S00160,471,490,Neutropenia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002924,S00160,663,670,Anaemia,Blood and lymphatic system,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002925,S00160,47,48,Alanine aminotransferase increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002926,S00160,429,445,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002927,S00160,277,292,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002928,S00160,299,301,Aphasia,Nervous system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002929,S00160,490,515,Fatigue,General disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002930,S00160,673,686,Complement activation,Immune system disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002931,S00160,168,171,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002932,S00160,627,636,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002933,S00160,717,722,Cytomegalovirus infection,Infections and infestations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002934,S00160,488,493,Pyrexia,General disorders,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002935,S00160,448,466,Anaemia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002936,S00160,338,357,Headache,Nervous system disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002937,S00160,524,549,Nausea,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002938,S00160,667,687,Pyrexia,General disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002939,S00160,317,333,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002940,S00160,373,401,Neutropenia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002941,S00161,81,109,Cough,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002942,S00161,9,25,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002943,S00161,562,589,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0002944,S00161,359,377,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002945,S00161,235,251,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002946,S00161,706,730,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0002947,S00161,506,532,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002948,S00161,645,672,Vomiting,Gastrointestinal disorders,4,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002949,S00161,579,603,Aphasia,Nervous system disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0002950,S00161,16,29,Fatigue,General disorders,1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0002951,S00161,244,264,Complement activation,Immune system disorders,3,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0002952,S00161,432,440,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002953,S00161,309,322,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002954,S00162,6,19,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0002955,S00162,13,29,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0002956,S00162,112,120,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0002957,S00162,682,684,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002958,S00162,612,631,Seizure,Nervous system disorders,4,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0002959,S00162,723,727,Anaemia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002960,S00162,481,510,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002961,S00162,75,82,Seizure,Nervous system disorders,3,N,N,None,Unknown,N,0,N,0,N,N,N
AE0002962,S00162,9,28,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0002963,S00162,579,593,Aspartate aminotransferase increased,Investigations,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002964,S00162,74,96,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002965,S00162,381,391,Thrombotic microangiopathy,Blood and lymphatic system,5,N,N,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0002966,S00162,399,421,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002967,S00162,168,179,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0002968,S00162,630,635,Neutropenia,Blood and lymphatic system,1,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0002969,S00162,296,305,Sepsis,Infections and infestations,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002970,S00162,524,533,Cytomegalovirus infection,Infections and infestations,3,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0002971,S00162,99,112,Bilirubin increased,Investigations,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002972,S00162,453,481,Anaemia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002973,S00162,237,263,Cytomegalovirus infection,Infections and infestations,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0002974,S00162,35,51,Cytomegalovirus infection,Infections and infestations,4,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0002975,S00162,591,596,Sepsis,Infections and infestations,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002976,S00162,393,408,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002977,S00162,497,510,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002978,S00162,193,213,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0002979,S00162,404,430,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0002980,S00162,599,615,Complement activation,Immune system disorders,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0002981,S00162,186,193,Thrombocytopenia,Blood and lymphatic system,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002982,S00162,203,204,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002983,S00162,266,286,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002984,S00162,480,489,Cytomegalovirus infection,Infections and infestations,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0002985,S00163,655,669,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002986,S00163,471,500,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0002987,S00163,215,244,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0002988,S00163,640,654,Vomiting,Gastrointestinal disorders,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0002989,S00163,238,263,Sepsis,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002990,S00163,156,171,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002991,S00163,413,420,Nausea,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0002992,S00163,191,206,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0002993,S00163,549,575,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002994,S00163,68,93,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002995,S00163,218,235,Seizure,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0002996,S00163,513,514,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0002997,S00163,441,447,Nausea,Gastrointestinal disorders,1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0002998,S00163,658,668,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0002999,S00163,667,688,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003000,S00163,512,524,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003001,S00163,122,144,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003002,S00163,688,699,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003003,S00163,623,636,Seizure,Nervous system disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003004,S00163,492,505,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003005,S00163,71,77,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003006,S00163,176,178,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0003007,S00163,48,71,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003008,S00164,531,541,Neutropenia,Blood and lymphatic system,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003009,S00164,242,258,Sepsis,Infections and infestations,4,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003010,S00164,42,43,Hypotension,Vascular disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003011,S00164,428,456,Aphasia,Nervous system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003012,S00164,321,345,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003013,S00164,391,420,Neutropenia,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003014,S00164,95,103,Neutropenia,Blood and lymphatic system,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003015,S00164,673,691,Pyrexia,General disorders,4,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0003016,S00164,463,487,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0003017,S00164,25,43,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0003018,S00164,545,548,Headache,Nervous system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003019,S00164,612,635,Neutropenia,Blood and lymphatic system,4,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003020,S00164,80,85,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003021,S00166,17,25,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003022,S00166,477,491,Pyrexia,General disorders,3,Y,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003023,S00166,197,214,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003024,S00166,352,356,Complement activation,Immune system disorders,2,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0003025,S00166,518,525,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003026,S00166,525,543,Tachycardia,Cardiac disorders,1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0003027,S00166,406,409,Complement activation,Immune system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003028,S00166,194,209,Anaemia,Blood and lymphatic system,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003029,S00166,199,218,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0003030,S00166,477,499,Complement activation,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003031,S00166,553,575,Bilirubin increased,Investigations,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003032,S00166,556,585,Confusional state,Psychiatric disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003033,S00166,437,444,Seizure,Nervous system disorders,5,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003034,S00166,418,425,Sepsis,Infections and infestations,5,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003035,S00166,677,678,Complement activation,Immune system disorders,4,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0003036,S00166,85,88,Tremor,Nervous system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003037,S00166,124,139,Tachycardia,Cardiac disorders,1,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0003038,S00166,125,140,Neutropenia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003039,S00166,604,609,Fatigue,General disorders,2,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0003040,S00167,4,23,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0003041,S00167,6,21,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,2,N,Y,Corticosteroids,Recovered,N,0,Y,2,N,N,Y
AE0003042,S00167,148,152,Aspartate aminotransferase increased,Investigations,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0003043,S00167,492,511,Aspartate aminotransferase increased,Investigations,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003044,S00167,685,700,Sepsis,Infections and infestations,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003045,S00167,74,95,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003046,S00167,127,136,Neutropenia,Blood and lymphatic system,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003047,S00167,330,337,Headache,Nervous system disorders,3,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003048,S00167,419,436,Bilirubin increased,Investigations,1,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0003049,S00167,728,750,Fatigue,General disorders,3,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0003050,S00167,701,729,Seizure,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0003051,S00167,618,620,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003052,S00167,459,481,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003053,S00167,40,60,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003054,S00167,413,440,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003055,S00167,301,304,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003056,S00167,41,45,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003057,S00167,447,473,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003058,S00167,687,713,Infusion related reaction,"Injury, poisoning, procedural",5,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0003059,S00167,320,323,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0003060,S00167,248,259,Infusion related reaction,"Injury, poisoning, procedural",4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003061,S00167,167,182,Aphasia,Nervous system disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003062,S00167,374,382,Seizure,Nervous system disorders,5,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003063,S00167,674,678,Fatigue,General disorders,2,N,N,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0003064,S00167,448,466,Tremor,Nervous system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003065,S00168,2,7,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0003066,S00168,647,650,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003067,S00168,716,722,Hypoxia,"Respiratory, thoracic, mediastinal",3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0003068,S00168,457,484,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0003069,S00168,36,43,Aphasia,Nervous system disorders,3,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0003070,S00168,677,700,Hypotension,Vascular disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003071,S00168,312,336,Thrombocytopenia,Blood and lymphatic system,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003072,S00168,371,382,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003073,S00168,369,394,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003074,S00168,328,354,Alanine aminotransferase increased,Investigations,5,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003075,S00168,411,427,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003076,S00168,513,528,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0003077,S00168,17,19,Pyrexia,General disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003078,S00168,638,653,Infusion related reaction,"Injury, poisoning, procedural",4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003079,S00168,719,739,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003080,S00168,206,223,Thrombocytopenia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0003081,S00168,59,83,Hypotension,Vascular disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003082,S00168,315,342,Nausea,Gastrointestinal disorders,3,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0003083,S00168,349,351,Anaemia,Blood and lymphatic system,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003084,S00168,402,426,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003085,S00168,104,115,Seizure,Nervous system disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003086,S00168,590,600,Thrombocytopenia,Blood and lymphatic system,2,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0003087,S00168,602,616,Neutropenia,Blood and lymphatic system,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003088,S00168,723,743,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003089,S00168,307,327,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003090,S00168,584,592,Fatigue,General disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003091,S00168,323,339,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0003092,S00168,84,100,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003093,S00168,130,159,Bilirubin increased,Investigations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003094,S00168,550,573,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003095,S00168,123,124,Anaemia,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003096,S00168,576,578,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003097,S00168,716,738,Aspartate aminotransferase increased,Investigations,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003098,S00168,452,460,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003099,S00169,702,705,Fatigue,General disorders,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003100,S00169,314,319,Headache,Nervous system disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003101,S00169,402,404,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0003102,S00169,168,187,Seizure,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003103,S00169,218,227,Hypotension,Vascular disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003104,S00169,651,659,Hypogammaglobulinaemia,Immune system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003105,S00169,206,216,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003106,S00169,411,413,Bilirubin increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003107,S00169,697,724,Confusional state,Psychiatric disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003108,S00169,657,666,Cytomegalovirus infection,Infections and infestations,3,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0003109,S00169,135,152,Thrombocytopenia,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003110,S00169,167,191,Confusional state,Psychiatric disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003111,S00169,542,546,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003112,S00169,683,686,Headache,Nervous system disorders,1,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0003113,S00169,548,575,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003114,S00169,306,307,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003115,S00169,717,743,Tremor,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003116,S00169,403,424,Alanine aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0003117,S00170,661,675,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003118,S00170,137,144,Aspartate aminotransferase increased,Investigations,3,Y,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0003119,S00170,532,557,Anaemia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003120,S00170,217,245,Anaemia,Blood and lymphatic system,2,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0003121,S00170,297,322,Tachycardia,Cardiac disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003122,S00170,93,97,Fatigue,General disorders,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0003123,S00170,491,496,Hypogammaglobulinaemia,Immune system disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003124,S00170,495,520,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003125,S00170,658,686,Confusional state,Psychiatric disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003126,S00170,334,354,Seizure,Nervous system disorders,2,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0003127,S00170,566,576,Alanine aminotransferase increased,Investigations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003128,S00170,195,211,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0003129,S00170,414,436,Infusion related reaction,"Injury, poisoning, procedural",4,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003130,S00170,681,686,Mucosal inflammation,Gastrointestinal disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003131,S00170,330,345,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003132,S00171,93,101,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003133,S00171,93,104,Mucosal inflammation,Gastrointestinal disorders,4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003134,S00171,659,663,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0003135,S00171,460,468,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003136,S00171,539,542,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003137,S00171,657,660,Cough,"Respiratory, thoracic, mediastinal",4,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003138,S00171,684,698,Nausea,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003139,S00171,129,132,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003140,S00171,590,599,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0003141,S00171,226,242,Vomiting,Gastrointestinal disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003142,S00171,314,336,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003143,S00171,146,153,Headache,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0003144,S00171,587,597,Sepsis,Infections and infestations,3,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0003145,S00171,435,455,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003146,S00171,268,294,Sepsis,Infections and infestations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003147,S00171,579,590,Anaemia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003148,S00171,546,551,Mucosal inflammation,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003149,S00171,175,192,Pyrexia,General disorders,3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0003150,S00172,685,695,Sepsis,Infections and infestations,3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003151,S00172,298,316,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0003152,S00172,288,290,Tremor,Nervous system disorders,3,Y,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0003153,S00172,430,435,Headache,Nervous system disorders,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0003154,S00172,646,673,Confusional state,Psychiatric disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003155,S00172,649,655,Tremor,Nervous system disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0003156,S00172,110,122,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003157,S00172,148,171,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003158,S00172,113,114,Tachycardia,Cardiac disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0003159,S00172,200,227,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003160,S00172,19,20,Diarrhoea,Gastrointestinal disorders,1,N,Y,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0003161,S00172,344,357,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0003162,S00172,491,507,Pyrexia,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003163,S00172,380,399,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003164,S00173,390,391,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003165,S00173,221,236,Tremor,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003166,S00173,424,433,Neutropenia,Blood and lymphatic system,4,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0003167,S00173,569,598,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003168,S00173,718,727,Seizure,Nervous system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003169,S00173,161,172,Headache,Nervous system disorders,1,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0003170,S00173,279,303,Confusional state,Psychiatric disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003171,S00173,538,546,Aphasia,Nervous system disorders,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0003172,S00173,203,205,Fatigue,General disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003173,S00173,699,712,Aphasia,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003174,S00173,547,553,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0003175,S00173,610,611,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003176,S00173,559,577,Aphasia,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003177,S00173,456,478,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0003178,S00173,474,499,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003179,S00173,553,554,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003180,S00173,459,469,Nausea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0003181,S00173,169,192,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003182,S00173,264,293,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003183,S00174,2,4,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0003184,S00174,12,16,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,3,Y,Y,Corticosteroids,Recovered,N,0,Y,3,N,N,Y
AE0003185,S00174,484,486,Aphasia,Nervous system disorders,2,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0003186,S00174,164,176,Hypogammaglobulinaemia,Immune system disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003187,S00174,285,298,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,Y,Y
AE0003188,S00174,587,595,Mucosal inflammation,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003189,S00174,323,352,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003190,S00174,454,459,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003191,S00174,706,712,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003192,S00174,183,187,Tremor,Nervous system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003193,S00174,474,485,Hypotension,Vascular disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003194,S00174,486,487,Anaemia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003195,S00174,709,736,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003196,S00174,601,620,Fatigue,General disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003197,S00174,666,687,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0003198,S00174,490,497,Pyrexia,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003199,S00174,2,7,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003200,S00174,220,242,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003201,S00174,703,712,Seizure,Nervous system disorders,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003202,S00174,396,403,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003203,S00174,106,125,Anaemia,Blood and lymphatic system,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003204,S00174,278,300,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0003205,S00174,259,262,Pyrexia,General disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003206,S00174,468,477,Pyrexia,General disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003207,S00174,634,651,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003208,S00174,86,89,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0003209,S00174,189,214,Aspartate aminotransferase increased,Investigations,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003210,S00176,427,452,Bilirubin increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003211,S00176,454,472,Aspartate aminotransferase increased,Investigations,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003212,S00176,506,508,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003213,S00176,204,217,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003214,S00176,615,644,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003215,S00176,409,438,Thrombocytopenia,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003216,S00176,35,47,Complement activation,Immune system disorders,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003217,S00177,36,54,Aspartate aminotransferase increased,Investigations,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0003218,S00177,50,74,Tremor,Nervous system disorders,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0003219,S00177,594,609,Hypotension,Vascular disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003220,S00177,293,309,Aspartate aminotransferase increased,Investigations,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003221,S00177,549,563,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0003222,S00177,723,725,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003223,S00177,329,342,Anaemia,Blood and lymphatic system,3,N,Y,Dose modification,Fatal,N,0,N,0,N,N,N
AE0003224,S00177,158,177,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003225,S00177,28,57,Complement activation,Immune system disorders,2,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0003226,S00177,92,107,Hypogammaglobulinaemia,Immune system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003227,S00177,709,716,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003228,S00177,362,374,Headache,Nervous system disorders,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003229,S00177,433,450,Vomiting,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003230,S00177,466,487,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003231,S00177,513,514,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003232,S00177,704,707,Neutropenia,Blood and lymphatic system,5,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003233,S00177,293,318,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003234,S00178,567,589,Sepsis,Infections and infestations,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003235,S00178,279,299,Cytomegalovirus infection,Infections and infestations,3,Y,Y,None,Recovering,N,0,N,0,N,N,N
AE0003236,S00178,157,172,Tachycardia,Cardiac disorders,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0003237,S00178,670,696,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003238,S00178,80,97,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003239,S00178,681,687,Bilirubin increased,Investigations,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003240,S00178,603,629,Cytomegalovirus infection,Infections and infestations,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0003241,S00178,67,80,Cough,"Respiratory, thoracic, mediastinal",2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003242,S00178,80,90,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0003243,S00178,713,736,Mucosal inflammation,Gastrointestinal disorders,2,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0003244,S00178,4,13,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003245,S00178,615,625,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003246,S00178,514,515,Thrombocytopenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003247,S00178,112,117,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0003248,S00178,401,427,Seizure,Nervous system disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0003249,S00178,232,238,Hypotension,Vascular disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003250,S00178,521,522,Aphasia,Nervous system disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003251,S00178,223,224,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003252,S00178,56,57,Sepsis,Infections and infestations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003253,S00179,3,11,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0003254,S00179,5,6,Pyrexia,General disorders,3,Y,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0003255,S00179,474,478,Cytomegalovirus infection,Infections and infestations,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003256,S00179,452,468,Tremor,Nervous system disorders,1,N,N,Drug interrupted,Fatal,N,0,N,0,N,N,N
AE0003257,S00179,156,179,Neutropenia,Blood and lymphatic system,3,Y,Y,None,Recovering,N,0,N,0,N,N,N
AE0003258,S00179,392,405,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003259,S00179,449,469,Bilirubin increased,Investigations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003260,S00179,356,365,Seizure,Nervous system disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003261,S00179,286,308,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003262,S00179,633,662,Hypotension,Vascular disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003263,S00179,501,515,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003264,S00179,231,242,Headache,Nervous system disorders,1,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0003265,S00179,57,60,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003266,S00179,139,161,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Not recovered,N,0,N,0,N,Y,Y
AE0003267,S00179,411,419,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0003268,S00179,412,424,Aphasia,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003269,S00179,721,724,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003270,S00179,630,638,Tremor,Nervous system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003271,S00179,274,280,Headache,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003272,S00179,227,236,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0003273,S00179,437,439,Tachycardia,Cardiac disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0003274,S00179,22,51,Diarrhoea,Gastrointestinal disorders,1,N,N,Dose modification,Fatal,N,0,N,0,N,N,N
AE0003275,S00180,6,19,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0003276,S00180,125,126,Tachycardia,Cardiac disorders,2,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0003277,S00180,609,628,Complement activation,Immune system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003278,S00180,636,639,Fatigue,General disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003279,S00180,139,161,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003280,S00180,360,379,Complement activation,Immune system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003281,S00180,391,415,Thrombotic microangiopathy,Blood and lymphatic system,5,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0003282,S00180,592,621,Alanine aminotransferase increased,Investigations,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003283,S00180,259,268,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003284,S00180,144,146,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003285,S00180,5,34,Diarrhoea,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003286,S00180,453,470,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003287,S00180,434,461,Confusional state,Psychiatric disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003288,S00180,473,490,Diarrhoea,Gastrointestinal disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003289,S00180,662,663,Sepsis,Infections and infestations,3,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0003290,S00180,410,421,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003291,S00180,221,231,Sepsis,Infections and infestations,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003292,S00180,179,192,Neutropenia,Blood and lymphatic system,4,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0003293,S00180,171,199,Thrombocytopenia,Blood and lymphatic system,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003294,S00180,260,262,Pyrexia,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003295,S00180,53,75,Bilirubin increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003296,S00180,538,557,Pyrexia,General disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0003297,S00180,184,199,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003298,S00180,139,163,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003299,S00180,604,613,Aphasia,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003300,S00180,287,302,Tachycardia,Cardiac disorders,4,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003301,S00180,150,179,Seizure,Nervous system disorders,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003302,S00180,457,468,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003303,S00180,662,684,Aphasia,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0003304,S00180,151,156,Alanine aminotransferase increased,Investigations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003305,S00180,431,447,Alanine aminotransferase increased,Investigations,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003306,S00180,125,151,Neutropenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003307,S00180,607,635,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003308,S00180,636,655,Sepsis,Infections and infestations,3,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003309,S00180,157,173,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003310,S00180,462,473,Tachycardia,Cardiac disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003311,S00180,258,284,Neutropenia,Blood and lymphatic system,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003312,S00180,81,97,Aphasia,Nervous system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003313,S00180,92,113,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0003314,S00181,4,22,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0003315,S00181,372,401,Mucosal inflammation,Gastrointestinal disorders,5,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003316,S00181,693,720,Diarrhoea,Gastrointestinal disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003317,S00181,725,738,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003318,S00181,351,363,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,Y,Y
AE0003319,S00181,249,253,Confusional state,Psychiatric disorders,5,N,N,None,Unknown,N,0,N,0,N,N,N
AE0003320,S00181,392,421,Thrombocytopenia,Blood and lymphatic system,5,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0003321,S00181,58,79,Thrombocytopenia,Blood and lymphatic system,4,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0003322,S00181,378,393,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,Dose modification,Recovered,N,0,N,0,N,Y,Y
AE0003323,S00181,449,472,Sepsis,Infections and infestations,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003324,S00181,291,320,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003325,S00181,65,80,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003326,S00181,163,183,Complement activation,Immune system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003327,S00181,360,371,Vomiting,Gastrointestinal disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003328,S00181,413,438,Aspartate aminotransferase increased,Investigations,1,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0003329,S00181,683,712,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003330,S00181,374,379,Fatigue,General disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003331,S00181,178,186,Tachycardia,Cardiac disorders,3,N,N,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0003332,S00181,568,597,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003333,S00181,548,561,Fatigue,General disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003334,S00181,49,56,Tachycardia,Cardiac disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003335,S00181,355,360,Headache,Nervous system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003336,S00181,536,545,Tachycardia,Cardiac disorders,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003337,S00181,655,659,Thrombocytopenia,Blood and lymphatic system,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0003338,S00181,7,19,Aspartate aminotransferase increased,Investigations,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003339,S00181,249,273,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0003340,S00181,249,274,Nausea,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003341,S00181,602,631,Aphasia,Nervous system disorders,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003342,S00181,667,668,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003343,S00181,502,517,Bilirubin increased,Investigations,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0003344,S00181,161,165,Bilirubin increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003345,S00181,188,189,Anaemia,Blood and lymphatic system,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003346,S00181,290,308,Aspartate aminotransferase increased,Investigations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003347,S00181,660,672,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003348,S00181,657,684,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003349,S00181,176,195,Aphasia,Nervous system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003350,S00181,411,433,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0003351,S00181,0,16,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003352,S00182,3,15,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0003353,S00182,589,612,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003354,S00182,124,129,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003355,S00182,432,457,Aphasia,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003356,S00182,116,125,Fatigue,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003357,S00182,464,481,Alanine aminotransferase increased,Investigations,1,N,N,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0003358,S00182,602,622,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003359,S00182,78,92,Vomiting,Gastrointestinal disorders,2,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0003360,S00182,213,242,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003361,S00182,96,110,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003362,S00182,163,165,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003363,S00182,676,689,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003364,S00182,400,421,Anaemia,Blood and lymphatic system,5,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003365,S00182,717,734,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003366,S00182,296,310,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003367,S00182,470,499,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003368,S00182,437,446,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003369,S00182,106,112,Vomiting,Gastrointestinal disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003370,S00182,546,569,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003371,S00182,418,430,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003372,S00182,396,420,Sepsis,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003373,S00182,573,597,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003374,S00182,514,531,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003375,S00182,78,102,Aspartate aminotransferase increased,Investigations,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003376,S00182,252,256,Aphasia,Nervous system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003377,S00182,611,628,Tremor,Nervous system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003378,S00182,669,677,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003379,S00182,394,407,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003380,S00182,672,691,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003381,S00182,382,388,Confusional state,Psychiatric disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003382,S00182,182,191,Tachycardia,Cardiac disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003383,S00183,83,101,Hepatocellular injury,Hepatobiliary disorders,4,Y,Y,Tocilizumab,Recovered with sequelae,Y,0,N,0,Y,N,Y
AE0003384,S00183,331,358,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003385,S00183,103,108,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0003386,S00183,199,216,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003387,S00183,645,648,Neutropenia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003388,S00183,53,66,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003389,S00183,390,397,Aphasia,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003390,S00183,68,74,Vomiting,Gastrointestinal disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003391,S00183,431,449,Fatigue,General disorders,3,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0003392,S00183,249,271,Bilirubin increased,Investigations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003393,S00183,139,151,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0003394,S00184,84,106,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003395,S00184,89,115,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003396,S00184,667,676,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003397,S00184,181,208,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003398,S00184,226,237,Complement activation,Immune system disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0003399,S00184,336,347,Sepsis,Infections and infestations,5,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003400,S00184,178,191,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003401,S00184,374,395,Hypotension,Vascular disorders,1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0003402,S00184,705,731,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003403,S00184,113,114,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003404,S00184,166,194,Neutropenia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003405,S00184,697,717,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003406,S00184,544,567,Sepsis,Infections and infestations,3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0003407,S00184,286,287,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003408,S00184,505,525,Aphasia,Nervous system disorders,4,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003409,S00184,524,531,Headache,Nervous system disorders,3,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0003410,S00184,359,381,Tremor,Nervous system disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0003411,S00184,452,480,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003412,S00184,667,679,Neutropenia,Blood and lymphatic system,2,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0003413,S00184,174,202,Sepsis,Infections and infestations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003414,S00184,697,700,Nausea,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003415,S00184,498,522,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003416,S00185,7,24,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0003417,S00185,425,453,Aphasia,Nervous system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003418,S00185,144,168,Aspartate aminotransferase increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003419,S00185,247,275,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003420,S00185,588,614,Complement activation,Immune system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003421,S00185,522,533,Neutropenia,Blood and lymphatic system,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003422,S00185,649,669,Vomiting,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003423,S00185,544,556,Pyrexia,General disorders,3,Y,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0003424,S00185,283,312,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003425,S00185,326,330,Hypotension,Vascular disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003426,S00185,296,308,Sepsis,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003427,S00185,257,264,Aphasia,Nervous system disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003428,S00185,160,185,Headache,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003429,S00185,318,324,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0003430,S00185,633,638,Fatigue,General disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003431,S00185,57,80,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0003432,S00185,643,653,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0003433,S00185,4,7,Thrombocytopenia,Blood and lymphatic system,2,N,N,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0003434,S00185,329,341,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003435,S00185,175,178,Fatigue,General disorders,1,N,N,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0003436,S00185,165,194,Neutropenia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003437,S00185,64,65,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0003438,S00185,201,205,Bilirubin increased,Investigations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003439,S00185,632,635,Fatigue,General disorders,1,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0003440,S00185,431,438,Nausea,Gastrointestinal disorders,4,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003441,S00185,201,205,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003442,S00185,118,145,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003443,S00185,249,272,Sepsis,Infections and infestations,4,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0003444,S00185,251,262,Bilirubin increased,Investigations,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003445,S00185,666,679,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003446,S00185,318,322,Diarrhoea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003447,S00185,590,618,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0003448,S00185,382,399,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003449,S00185,309,328,Anaemia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003450,S00185,126,144,Aphasia,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003451,S00185,221,226,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003452,S00185,275,283,Cytomegalovirus infection,Infections and infestations,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003453,S00185,558,585,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003454,S00185,47,60,Anaemia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003455,S00185,77,101,Vomiting,Gastrointestinal disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003456,S00185,209,235,Tremor,Nervous system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003457,S00185,368,369,Sepsis,Infections and infestations,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003458,S00186,5,23,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0003459,S00186,7,16,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0003460,S00186,693,717,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003461,S00186,493,522,Aphasia,Nervous system disorders,3,Y,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0003462,S00186,516,530,Seizure,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003463,S00186,535,549,Seizure,Nervous system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003464,S00186,459,470,Complement activation,Immune system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003465,S00186,668,678,Pyrexia,General disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003466,S00186,700,704,Tachycardia,Cardiac disorders,3,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0003467,S00186,49,57,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003468,S00186,534,549,Thrombocytopenia,Blood and lymphatic system,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003469,S00186,292,314,Sepsis,Infections and infestations,4,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0003470,S00186,99,103,Vomiting,Gastrointestinal disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003471,S00186,491,503,Cough,"Respiratory, thoracic, mediastinal",2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003472,S00186,26,45,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003473,S00186,634,662,Alanine aminotransferase increased,Investigations,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0003474,S00186,324,352,Bilirubin increased,Investigations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003475,S00186,444,464,Tachycardia,Cardiac disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003476,S00186,625,639,Mucosal inflammation,Gastrointestinal disorders,2,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0003477,S00186,179,207,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003478,S00186,221,234,Alanine aminotransferase increased,Investigations,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003479,S00186,677,689,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003480,S00186,631,632,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003481,S00186,162,187,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003482,S00186,636,641,Neutropenia,Blood and lymphatic system,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003483,S00186,198,202,Pyrexia,General disorders,2,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0003484,S00186,578,602,Nausea,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003485,S00186,499,504,Nausea,Gastrointestinal disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003486,S00186,60,87,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003487,S00187,89,102,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003488,S00187,694,696,Tachycardia,Cardiac disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0003489,S00187,431,436,Headache,Nervous system disorders,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003490,S00187,21,30,Thrombocytopenia,Blood and lymphatic system,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003491,S00187,563,566,Nausea,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003492,S00187,56,81,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003493,S00187,249,255,Diarrhoea,Gastrointestinal disorders,2,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0003494,S00187,533,550,Seizure,Nervous system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003495,S00187,261,290,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003496,S00187,617,645,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003497,S00187,419,438,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003498,S00187,435,443,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003499,S00187,418,419,Pyrexia,General disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003500,S00187,471,496,Seizure,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003501,S00187,47,63,Confusional state,Psychiatric disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003502,S00187,150,165,Aphasia,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003503,S00187,273,292,Aphasia,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003504,S00187,171,176,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003505,S00187,57,66,Aspartate aminotransferase increased,Investigations,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003506,S00187,656,666,Aphasia,Nervous system disorders,5,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0003507,S00187,410,435,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0003508,S00187,113,130,Neutropenia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003509,S00187,702,722,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003510,S00188,475,496,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003511,S00188,2,3,Nausea,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003512,S00188,384,390,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0003513,S00188,73,92,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003514,S00188,350,361,Neutropenia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003515,S00188,635,638,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003516,S00188,570,589,Complement activation,Immune system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003517,S00188,603,624,Complement activation,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003518,S00188,256,285,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,Y,Y
AE0003519,S00188,372,395,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0003520,S00188,161,182,Thrombocytopenia,Blood and lymphatic system,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003521,S00189,6,20,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0003522,S00189,172,193,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003523,S00189,104,111,Thrombocytopenia,Blood and lymphatic system,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003524,S00189,197,224,Bilirubin increased,Investigations,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003525,S00189,25,38,Pyrexia,General disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003526,S00189,635,659,Aphasia,Nervous system disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003527,S00189,721,746,Anaemia,Blood and lymphatic system,3,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0003528,S00189,697,700,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003529,S00189,382,399,Fatigue,General disorders,2,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0003530,S00189,693,721,Neutropenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003531,S00189,461,482,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003532,S00189,5,30,Bilirubin increased,Investigations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003533,S00189,703,717,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,None,Recovering,N,0,N,0,N,Y,Y
AE0003534,S00189,179,182,Aphasia,Nervous system disorders,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003535,S00189,389,411,Sepsis,Infections and infestations,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003536,S00189,159,179,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,Dose modification,Recovered,N,0,N,0,N,Y,Y
AE0003537,S00189,717,737,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0003538,S00189,70,88,Seizure,Nervous system disorders,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003539,S00189,277,287,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003540,S00189,386,397,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003541,S00189,483,506,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003542,S00189,392,403,Hypotension,Vascular disorders,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003543,S00189,549,575,Hypotension,Vascular disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003544,S00189,632,656,Mucosal inflammation,Gastrointestinal disorders,2,N,N,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0003545,S00190,414,442,Cytomegalovirus infection,Infections and infestations,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003546,S00190,165,188,Thrombotic microangiopathy,Blood and lymphatic system,4,Y,N,None,Not recovered,N,0,N,0,N,Y,Y
AE0003547,S00190,194,219,Thrombotic microangiopathy,Blood and lymphatic system,5,N,N,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0003548,S00190,622,633,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0003549,S00190,87,93,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003550,S00190,54,75,Aspartate aminotransferase increased,Investigations,4,N,Y,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0003551,S00190,425,436,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003552,S00190,539,556,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003553,S00190,539,545,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003554,S00190,113,128,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003555,S00190,511,533,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003556,S00190,168,196,Pyrexia,General disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003557,S00190,361,387,Diarrhoea,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003558,S00190,550,569,Aphasia,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003559,S00190,32,35,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003560,S00190,483,500,Headache,Nervous system disorders,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003561,S00190,311,322,Bilirubin increased,Investigations,2,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0003562,S00190,472,488,Sepsis,Infections and infestations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003563,S00190,304,306,Infusion related reaction,"Injury, poisoning, procedural",4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003564,S00191,220,224,Bilirubin increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003565,S00191,276,297,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003566,S00191,616,621,Aphasia,Nervous system disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003567,S00191,483,490,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003568,S00191,255,266,Diarrhoea,Gastrointestinal disorders,3,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003569,S00191,68,82,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003570,S00191,371,393,Headache,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003571,S00191,598,612,Confusional state,Psychiatric disorders,3,Y,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003572,S00191,498,502,Confusional state,Psychiatric disorders,3,Y,N,None,Unknown,N,0,N,0,N,N,N
AE0003573,S00191,564,590,Sepsis,Infections and infestations,3,N,N,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0003574,S00191,306,322,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003575,S00191,169,180,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003576,S00191,578,585,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0003577,S00191,446,463,Aspartate aminotransferase increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003578,S00191,554,576,Nausea,Gastrointestinal disorders,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003579,S00191,468,494,Vomiting,Gastrointestinal disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003580,S00191,586,597,Cytomegalovirus infection,Infections and infestations,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003581,S00191,573,585,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003582,S00191,12,39,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003583,S00191,721,747,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,Y,Y
AE0003584,S00191,585,601,Fatigue,General disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003585,S00191,144,149,Sepsis,Infections and infestations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0003586,S00191,418,447,Aphasia,Nervous system disorders,5,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003587,S00191,264,281,Neutropenia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003588,S00191,718,740,Aphasia,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003589,S00192,511,518,Tremor,Nervous system disorders,3,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0003590,S00192,590,603,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003591,S00192,175,184,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003592,S00192,657,664,Confusional state,Psychiatric disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003593,S00192,197,204,Anaemia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003594,S00192,535,542,Pyrexia,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003595,S00192,677,683,Seizure,Nervous system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003596,S00192,37,40,Complement activation,Immune system disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003597,S00192,636,647,Headache,Nervous system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003598,S00192,322,348,Hypotension,Vascular disorders,3,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0003599,S00192,184,194,Tachycardia,Cardiac disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003600,S00192,604,624,Headache,Nervous system disorders,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0003601,S00192,603,605,Anaemia,Blood and lymphatic system,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0003602,S00192,241,255,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003603,S00192,41,46,Confusional state,Psychiatric disorders,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003604,S00192,348,366,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003605,S00192,122,149,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003606,S00193,385,399,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003607,S00193,82,99,Aspartate aminotransferase increased,Investigations,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003608,S00193,521,531,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003609,S00193,265,280,Hypogammaglobulinaemia,Immune system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003610,S00193,410,439,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0003611,S00193,63,85,Bilirubin increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003612,S00193,315,317,Fatigue,General disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003613,S00193,39,66,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003614,S00194,6,16,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0003615,S00194,724,728,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003616,S00194,690,704,Tachycardia,Cardiac disorders,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003617,S00194,97,101,Bilirubin increased,Investigations,2,N,Y,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0003618,S00194,598,600,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003619,S00194,190,215,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Not recovered,N,0,N,0,N,Y,Y
AE0003620,S00194,180,196,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0003621,S00194,148,160,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003622,S00194,142,165,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003623,S00194,520,536,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003624,S00194,235,257,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Hospitalization,Recovered,N,0,N,0,N,Y,Y
AE0003625,S00194,4,5,Anaemia,Blood and lymphatic system,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003626,S00194,170,187,Hypogammaglobulinaemia,Immune system disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0003627,S00194,530,542,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003628,S00194,354,359,Complement activation,Immune system disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003629,S00194,316,334,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0003630,S00194,12,40,Fatigue,General disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003631,S00194,167,195,Tachycardia,Cardiac disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003632,S00194,248,269,Fatigue,General disorders,2,N,Y,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0003633,S00194,629,652,Cytomegalovirus infection,Infections and infestations,3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0003634,S00194,661,690,Tachycardia,Cardiac disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003635,S00194,356,370,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003636,S00194,707,719,Aphasia,Nervous system disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003637,S00194,144,155,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003638,S00194,318,338,Sepsis,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003639,S00194,675,682,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003640,S00194,515,532,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003641,S00194,210,224,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003642,S00194,193,203,Aphasia,Nervous system disorders,4,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0003643,S00194,6,27,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Drug interrupted,Fatal,N,0,N,0,N,N,N
AE0003644,S00197,417,441,Tremor,Nervous system disorders,3,Y,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003645,S00197,88,106,Bilirubin increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003646,S00197,325,346,Bilirubin increased,Investigations,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0003647,S00197,444,450,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003648,S00197,172,196,Fatigue,General disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003649,S00197,537,561,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003650,S00197,485,507,Cytomegalovirus infection,Infections and infestations,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003651,S00197,598,616,Hypogammaglobulinaemia,Immune system disorders,2,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0003652,S00197,399,413,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,None,Fatal,N,0,N,0,N,N,N
AE0003653,S00197,194,203,Aphasia,Nervous system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003654,S00198,159,177,Hypoxia,"Respiratory, thoracic, mediastinal",3,Y,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003655,S00198,600,601,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003656,S00198,181,183,Hypogammaglobulinaemia,Immune system disorders,3,Y,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0003657,S00198,527,535,Neutropenia,Blood and lymphatic system,2,N,Y,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0003658,S00198,124,145,Alanine aminotransferase increased,Investigations,3,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003659,S00198,367,373,Aphasia,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003660,S00198,621,646,Complement activation,Immune system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003661,S00198,467,476,Cytomegalovirus infection,Infections and infestations,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003662,S00198,685,706,Headache,Nervous system disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003663,S00198,722,723,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,None,Recovering,N,0,N,0,N,Y,Y
AE0003664,S00198,36,60,Headache,Nervous system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003665,S00198,512,535,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003666,S00198,711,719,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003667,S00198,705,729,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003668,S00198,72,101,Pyrexia,General disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003669,S00198,98,119,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003670,S00198,519,529,Bilirubin increased,Investigations,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003671,S00198,560,568,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003672,S00198,496,503,Diarrhoea,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003673,S00198,167,181,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0003674,S00198,337,357,Alanine aminotransferase increased,Investigations,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003675,S00198,264,269,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003676,S00198,690,698,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003677,S00198,537,556,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003678,S00198,607,615,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003679,S00198,511,534,Tachycardia,Cardiac disorders,1,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0003680,S00198,293,305,Vomiting,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003681,S00198,350,365,Fatigue,General disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003682,S00198,581,594,Anaemia,Blood and lymphatic system,1,N,N,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0003683,S00198,174,183,Sepsis,Infections and infestations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003684,S00198,428,439,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,Hospitalization,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0003685,S00198,520,544,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003686,S00198,524,544,Confusional state,Psychiatric disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003687,S00198,490,509,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003688,S00198,55,61,Hypotension,Vascular disorders,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003689,S00199,488,495,Vomiting,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003690,S00199,527,536,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003691,S00199,709,727,Seizure,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003692,S00199,379,399,Cytomegalovirus infection,Infections and infestations,3,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0003693,S00199,170,185,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,Y,Y
AE0003694,S00199,203,213,Thrombocytopenia,Blood and lymphatic system,3,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0003695,S00199,280,306,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003696,S00199,17,32,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003697,S00199,98,123,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003698,S00199,456,469,Pyrexia,General disorders,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003699,S00199,336,351,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003700,S00199,205,212,Confusional state,Psychiatric disorders,4,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0003701,S00199,234,243,Pyrexia,General disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003702,S00199,294,314,Sepsis,Infections and infestations,1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0003703,S00199,501,509,Sepsis,Infections and infestations,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003704,S00199,430,443,Cytomegalovirus infection,Infections and infestations,5,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003705,S00199,242,257,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003706,S00199,129,134,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003707,S00199,67,83,Confusional state,Psychiatric disorders,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003708,S00200,662,682,Sepsis,Infections and infestations,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003709,S00200,193,212,Bilirubin increased,Investigations,3,N,N,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0003710,S00200,332,360,Aspartate aminotransferase increased,Investigations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003711,S00200,560,562,Complement activation,Immune system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003712,S00200,542,560,Cytomegalovirus infection,Infections and infestations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003713,S00200,358,387,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003714,S00200,412,420,Mucosal inflammation,Gastrointestinal disorders,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003715,S00200,406,424,Aphasia,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003716,S00200,329,337,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003717,S00200,65,76,Aphasia,Nervous system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003718,S00200,134,161,Vomiting,Gastrointestinal disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0003719,S00200,257,285,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003720,S00200,690,700,Thrombocytopenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0003721,S00200,674,683,Sepsis,Infections and infestations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003722,S00200,92,105,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003723,S00200,108,119,Tachycardia,Cardiac disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003724,S00200,137,159,Thrombocytopenia,Blood and lymphatic system,3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0003725,S00200,204,222,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003726,S00200,17,36,Aphasia,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003727,S00200,530,552,Aphasia,Nervous system disorders,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003728,S00200,271,272,Nausea,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003729,S00200,205,231,Sepsis,Infections and infestations,4,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0003730,S00200,712,724,Vomiting,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003731,S00200,662,688,Confusional state,Psychiatric disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003732,S00200,708,736,Seizure,Nervous system disorders,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003733,S00200,372,381,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003734,S00201,206,219,Hypotension,Vascular disorders,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003735,S00201,556,572,Hypoxia,"Respiratory, thoracic, mediastinal",3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0003736,S00201,670,675,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,Dose modification,Recovered,N,0,N,0,N,Y,Y
AE0003737,S00201,264,276,Nausea,Gastrointestinal disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003738,S00201,197,215,Tachycardia,Cardiac disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0003739,S00201,31,45,Complement activation,Immune system disorders,3,Y,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003740,S00201,453,462,Complement activation,Immune system disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003741,S00201,610,614,Neutropenia,Blood and lymphatic system,5,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003742,S00201,168,181,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003743,S00201,603,615,Neutropenia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0003744,S00201,369,391,Complement activation,Immune system disorders,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003745,S00201,290,304,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003746,S00201,517,546,Anaemia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003747,S00201,581,593,Headache,Nervous system disorders,1,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0003748,S00201,708,730,Seizure,Nervous system disorders,1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0003749,S00201,670,695,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003750,S00201,495,508,Thrombocytopenia,Blood and lymphatic system,1,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0003751,S00201,326,340,Alanine aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003752,S00201,553,556,Tremor,Nervous system disorders,2,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0003753,S00201,352,373,Neutropenia,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003754,S00201,24,36,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,None,Not recovered,N,0,N,0,N,Y,Y
AE0003755,S00201,76,90,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003756,S00201,683,694,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003757,S00201,134,142,Seizure,Nervous system disorders,4,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003758,S00202,226,227,Hypogammaglobulinaemia,Immune system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003759,S00202,35,53,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0003760,S00202,284,307,Infusion related reaction,"Injury, poisoning, procedural",3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003761,S00202,667,681,Seizure,Nervous system disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003762,S00202,324,338,Thrombocytopenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003763,S00202,237,258,Aphasia,Nervous system disorders,4,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0003764,S00202,582,588,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003765,S00202,95,110,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003766,S00202,114,142,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003767,S00202,144,158,Neutropenia,Blood and lymphatic system,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003768,S00202,69,97,Neutropenia,Blood and lymphatic system,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003769,S00202,628,639,Tachycardia,Cardiac disorders,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0003770,S00202,118,120,Hypotension,Vascular disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003771,S00202,582,603,Aspartate aminotransferase increased,Investigations,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0003772,S00202,241,257,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003773,S00202,476,492,Thrombocytopenia,Blood and lymphatic system,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003774,S00202,315,323,Tremor,Nervous system disorders,4,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0003775,S00203,533,535,Aspartate aminotransferase increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003776,S00203,66,70,Tachycardia,Cardiac disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003777,S00203,148,170,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0003778,S00203,249,262,Aspartate aminotransferase increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003779,S00203,346,369,Fatigue,General disorders,1,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0003780,S00203,78,99,Anaemia,Blood and lymphatic system,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003781,S00204,458,467,Bilirubin increased,Investigations,3,Y,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0003782,S00204,607,629,Tremor,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003783,S00204,266,291,Diarrhoea,Gastrointestinal disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003784,S00204,713,716,Vomiting,Gastrointestinal disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003785,S00204,168,170,Cytomegalovirus infection,Infections and infestations,3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003786,S00204,307,326,Fatigue,General disorders,3,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003787,S00204,717,737,Tremor,Nervous system disorders,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003788,S00204,95,122,Aphasia,Nervous system disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003789,S00204,417,434,Fatigue,General disorders,3,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003790,S00205,27,42,Hepatocellular injury,Hepatobiliary disorders,3,Y,Y,Tocilizumab,Recovered,Y,0,N,0,Y,N,Y
AE0003791,S00205,587,609,Cytomegalovirus infection,Infections and infestations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003792,S00205,473,497,Bilirubin increased,Investigations,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003793,S00205,576,584,Vomiting,Gastrointestinal disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003794,S00205,127,141,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0003795,S00205,19,37,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0003796,S00205,580,602,Aphasia,Nervous system disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003797,S00205,124,149,Aspartate aminotransferase increased,Investigations,3,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0003798,S00205,186,198,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003799,S00205,587,591,Fatigue,General disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003800,S00205,23,31,Anaemia,Blood and lymphatic system,5,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003801,S00205,600,624,Thrombocytopenia,Blood and lymphatic system,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003802,S00206,486,514,Aspartate aminotransferase increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003803,S00206,109,132,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0003804,S00206,631,656,Fatigue,General disorders,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0003805,S00206,541,543,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003806,S00206,5,26,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003807,S00206,218,244,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003808,S00206,385,414,Sepsis,Infections and infestations,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003809,S00206,470,476,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003810,S00206,228,250,Tachycardia,Cardiac disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003811,S00206,290,317,Alanine aminotransferase increased,Investigations,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003812,S00206,505,521,Neutropenia,Blood and lymphatic system,4,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0003813,S00206,638,659,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003814,S00206,262,270,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003815,S00206,311,327,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0003816,S00206,469,493,Thrombocytopenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003817,S00206,359,385,Alanine aminotransferase increased,Investigations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003818,S00206,569,575,Vomiting,Gastrointestinal disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003819,S00206,332,353,Complement activation,Immune system disorders,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003820,S00206,186,193,Pyrexia,General disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0003821,S00206,169,192,Anaemia,Blood and lymphatic system,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003822,S00206,427,446,Neutropenia,Blood and lymphatic system,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003823,S00206,3,24,Anaemia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003824,S00206,123,144,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003825,S00206,420,445,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003826,S00206,257,263,Nausea,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003827,S00208,1,17,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0003828,S00208,164,190,Cough,"Respiratory, thoracic, mediastinal",3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0003829,S00208,115,118,Aphasia,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003830,S00208,667,682,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003831,S00208,169,191,Sepsis,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003832,S00208,269,289,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003833,S00208,172,189,Vomiting,Gastrointestinal disorders,2,N,Y,Dose modification,Fatal,N,0,N,0,N,N,N
AE0003834,S00208,161,184,Vomiting,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003835,S00208,312,341,Complement activation,Immune system disorders,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003836,S00208,522,535,Vomiting,Gastrointestinal disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003837,S00208,449,478,Cytomegalovirus infection,Infections and infestations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003838,S00208,391,417,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003839,S00208,257,280,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003840,S00208,219,228,Headache,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0003841,S00208,709,711,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003842,S00208,468,478,Fatigue,General disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003843,S00208,558,577,Neutropenia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003844,S00208,327,330,Aphasia,Nervous system disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003845,S00208,0,17,Nausea,Gastrointestinal disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0003846,S00208,69,81,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003847,S00208,661,685,Aphasia,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003848,S00208,104,117,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0003849,S00208,141,170,Headache,Nervous system disorders,3,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0003850,S00208,550,556,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0003851,S00208,563,576,Thrombocytopenia,Blood and lymphatic system,3,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003852,S00208,451,464,Nausea,Gastrointestinal disorders,3,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0003853,S00208,489,503,Headache,Nervous system disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0003854,S00208,36,52,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0003855,S00208,248,274,Fatigue,General disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003856,S00208,683,702,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003857,S00208,245,274,Diarrhoea,Gastrointestinal disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003858,S00209,455,479,Thrombocytopenia,Blood and lymphatic system,3,Y,Y,None,Recovering,N,0,N,0,N,N,N
AE0003859,S00209,516,544,Cytomegalovirus infection,Infections and infestations,1,N,N,Drug interrupted,Fatal,N,0,N,0,N,N,N
AE0003860,S00209,25,53,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003861,S00209,53,60,Anaemia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003862,S00209,494,518,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003863,S00209,182,200,Tremor,Nervous system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003864,S00209,375,396,Hypotension,Vascular disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0003865,S00209,456,481,Nausea,Gastrointestinal disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003866,S00209,195,205,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003867,S00209,643,656,Bilirubin increased,Investigations,3,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0003868,S00210,215,241,Infusion related reaction,"Injury, poisoning, procedural",3,Y,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0003869,S00210,263,267,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003870,S00210,429,445,Aspartate aminotransferase increased,Investigations,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0003871,S00210,102,103,Aspartate aminotransferase increased,Investigations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0003872,S00210,234,261,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003873,S00210,143,163,Sepsis,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003874,S00210,40,56,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003875,S00210,50,75,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0003876,S00210,183,202,Thrombotic microangiopathy,Blood and lymphatic system,5,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0003877,S00210,576,602,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003878,S00211,2,11,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0003879,S00211,11,18,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0003880,S00211,354,357,Complement activation,Immune system disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003881,S00211,24,31,Pyrexia,General disorders,3,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0003882,S00211,241,256,Aspartate aminotransferase increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003883,S00211,611,624,Aphasia,Nervous system disorders,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003884,S00211,531,550,Aphasia,Nervous system disorders,2,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0003885,S00211,377,387,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003886,S00211,477,502,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003887,S00211,38,43,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003888,S00211,195,217,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003889,S00211,138,154,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003890,S00211,491,499,Pyrexia,General disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003891,S00211,572,595,Anaemia,Blood and lymphatic system,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003892,S00211,499,501,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003893,S00211,153,179,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003894,S00211,220,245,Aspartate aminotransferase increased,Investigations,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003895,S00211,184,185,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0003896,S00211,431,441,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,Hospitalization,Recovering,N,0,N,0,N,Y,Y
AE0003897,S00211,250,266,Neutropenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0003898,S00211,467,488,Sepsis,Infections and infestations,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003899,S00211,118,125,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0003900,S00211,609,622,Headache,Nervous system disorders,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003901,S00211,471,489,Anaemia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003902,S00211,490,492,Aspartate aminotransferase increased,Investigations,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003903,S00211,651,673,Alanine aminotransferase increased,Investigations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003904,S00211,503,527,Sepsis,Infections and infestations,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0003905,S00211,323,352,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003906,S00211,529,557,Seizure,Nervous system disorders,5,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0003907,S00211,24,38,Seizure,Nervous system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003908,S00211,460,467,Neutropenia,Blood and lymphatic system,3,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0003909,S00211,9,34,Seizure,Nervous system disorders,3,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003910,S00211,92,107,Diarrhoea,Gastrointestinal disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003911,S00212,260,286,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0003912,S00212,41,47,Sepsis,Infections and infestations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003913,S00212,187,208,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003914,S00212,187,192,Complement activation,Immune system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003915,S00212,425,440,Cough,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003916,S00212,659,670,Mucosal inflammation,Gastrointestinal disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003917,S00212,2,13,Hypotension,Vascular disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003918,S00212,454,475,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003919,S00212,330,338,Bilirubin increased,Investigations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003920,S00212,190,216,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003921,S00213,50,55,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003922,S00213,514,529,Aphasia,Nervous system disorders,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0003923,S00213,86,110,Tremor,Nervous system disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003924,S00213,14,31,Alanine aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003925,S00213,290,317,Vomiting,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003926,S00213,134,160,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003927,S00213,83,108,Neutropenia,Blood and lymphatic system,1,N,N,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0003928,S00213,494,506,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003929,S00213,34,55,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003930,S00213,323,325,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0003931,S00213,10,29,Pyrexia,General disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003932,S00213,17,35,Fatigue,General disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003933,S00213,457,462,Diarrhoea,Gastrointestinal disorders,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0003934,S00214,2,10,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0003935,S00214,8,18,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,3,Y,Y,Corticosteroids,Recovered,N,0,Y,3,N,N,Y
AE0003936,S00214,676,681,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003937,S00214,539,549,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003938,S00214,675,703,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003939,S00214,533,552,Tremor,Nervous system disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003940,S00214,131,143,Fatigue,General disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003941,S00214,138,152,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003942,S00214,618,637,Tachycardia,Cardiac disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003943,S00214,130,132,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0003944,S00214,398,407,Thrombocytopenia,Blood and lymphatic system,2,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0003945,S00214,443,452,Aphasia,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003946,S00214,382,403,Aphasia,Nervous system disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003947,S00214,37,57,Thrombocytopenia,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003948,S00214,674,691,Pyrexia,General disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0003949,S00214,32,54,Anaemia,Blood and lymphatic system,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0003950,S00214,646,655,Tremor,Nervous system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003951,S00214,32,43,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0003952,S00214,523,538,Pyrexia,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003953,S00214,322,326,Tachycardia,Cardiac disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003954,S00214,237,255,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0003955,S00214,589,614,Seizure,Nervous system disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003956,S00214,559,569,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003957,S00214,150,157,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0003958,S00214,525,546,Diarrhoea,Gastrointestinal disorders,2,N,N,Dose modification,Unknown,N,0,N,0,N,N,N
AE0003959,S00214,147,171,Fatigue,General disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0003960,S00214,580,608,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003961,S00214,60,69,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0003962,S00214,699,706,Thrombocytopenia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003963,S00215,295,305,Sepsis,Infections and infestations,3,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0003964,S00215,620,638,Vomiting,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003965,S00215,632,657,Fatigue,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003966,S00215,631,660,Aphasia,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003967,S00215,132,146,Thrombocytopenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0003968,S00215,652,660,Bilirubin increased,Investigations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003969,S00215,5,13,Tremor,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003970,S00215,243,250,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003971,S00215,220,228,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003972,S00215,698,702,Hypotension,Vascular disorders,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0003973,S00215,369,387,Sepsis,Infections and infestations,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0003974,S00215,208,218,Complement activation,Immune system disorders,2,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0003975,S00215,689,703,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003976,S00215,341,365,Aspartate aminotransferase increased,Investigations,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003977,S00215,585,588,Neutropenia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003978,S00215,495,503,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003979,S00215,146,161,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003980,S00215,158,165,Vomiting,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0003981,S00215,206,209,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003982,S00215,257,276,Tachycardia,Cardiac disorders,2,N,Y,Dose modification,Unknown,N,0,N,0,N,N,N
AE0003983,S00215,354,366,Aspartate aminotransferase increased,Investigations,1,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0003984,S00216,1,5,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0003985,S00216,144,171,Vomiting,Gastrointestinal disorders,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003986,S00216,239,264,Confusional state,Psychiatric disorders,3,Y,N,None,Recovering,N,0,N,0,N,N,N
AE0003987,S00216,322,334,Diarrhoea,Gastrointestinal disorders,3,Y,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0003988,S00216,550,551,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003989,S00216,479,496,Diarrhoea,Gastrointestinal disorders,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0003990,S00216,399,418,Complement activation,Immune system disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0003991,S00216,297,325,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0003992,S00216,123,146,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003993,S00216,242,264,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0003994,S00216,370,387,Thrombocytopenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003995,S00216,613,631,Fatigue,General disorders,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0003996,S00216,168,172,Headache,Nervous system disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0003997,S00216,530,536,Anaemia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003998,S00216,630,647,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0003999,S00216,387,402,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004000,S00216,600,611,Tremor,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004001,S00216,643,671,Pyrexia,General disorders,5,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004002,S00216,324,346,Alanine aminotransferase increased,Investigations,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004003,S00216,30,34,Hypotension,Vascular disorders,3,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004004,S00216,614,636,Fatigue,General disorders,1,N,N,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0004005,S00216,122,138,Seizure,Nervous system disorders,5,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004006,S00216,65,73,Confusional state,Psychiatric disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004007,S00216,583,604,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004008,S00216,464,468,Anaemia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004009,S00216,216,218,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004010,S00216,692,705,Tachycardia,Cardiac disorders,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0004011,S00216,335,347,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004012,S00216,153,166,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004013,S00218,472,479,Anaemia,Blood and lymphatic system,2,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0004014,S00218,443,457,Complement activation,Immune system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004015,S00218,307,329,Aspartate aminotransferase increased,Investigations,1,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0004016,S00218,363,390,Cough,"Respiratory, thoracic, mediastinal",2,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0004017,S00218,203,204,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004018,S00218,70,89,Alanine aminotransferase increased,Investigations,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004019,S00218,546,551,Bilirubin increased,Investigations,1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0004020,S00218,389,415,Thrombocytopenia,Blood and lymphatic system,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004021,S00218,722,739,Thrombocytopenia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004022,S00218,559,580,Sepsis,Infections and infestations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004023,S00218,350,373,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004024,S00219,3,21,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0004025,S00219,134,150,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004026,S00219,672,699,Tremor,Nervous system disorders,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004027,S00219,650,659,Seizure,Nervous system disorders,4,N,N,None,Unknown,N,0,N,0,N,N,N
AE0004028,S00219,200,208,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004029,S00219,6,19,Complement activation,Immune system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004030,S00219,395,398,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004031,S00219,585,613,Complement activation,Immune system disorders,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004032,S00219,470,476,Hypotension,Vascular disorders,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004033,S00219,209,220,Alanine aminotransferase increased,Investigations,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0004034,S00219,390,413,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0004035,S00219,454,480,Complement activation,Immune system disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004036,S00219,138,155,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004037,S00219,318,342,Cytomegalovirus infection,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004038,S00219,457,468,Bilirubin increased,Investigations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004039,S00219,644,663,Complement activation,Immune system disorders,1,N,N,Hospitalization,Fatal,N,0,N,0,N,N,N
AE0004040,S00219,85,101,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004041,S00219,312,314,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004042,S00219,32,42,Nausea,Gastrointestinal disorders,3,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0004043,S00219,567,590,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004044,S00219,727,748,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004045,S00219,576,594,Aphasia,Nervous system disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004046,S00219,538,554,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004047,S00219,311,333,Aphasia,Nervous system disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0004048,S00219,106,117,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004049,S00220,712,738,Hypotension,Vascular disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004050,S00220,301,306,Seizure,Nervous system disorders,1,N,N,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0004051,S00220,497,514,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004052,S00220,205,232,Cytomegalovirus infection,Infections and infestations,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004053,S00220,192,221,Tachycardia,Cardiac disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004054,S00220,90,119,Bilirubin increased,Investigations,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004055,S00220,261,262,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004056,S00220,138,160,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004057,S00220,295,306,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004058,S00220,25,46,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004059,S00220,181,203,Infusion related reaction,"Injury, poisoning, procedural",4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004060,S00220,267,276,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004061,S00220,322,339,Complement activation,Immune system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004062,S00220,158,162,Pyrexia,General disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004063,S00220,336,340,Aspartate aminotransferase increased,Investigations,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004064,S00220,211,216,Aphasia,Nervous system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004065,S00221,457,476,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004066,S00221,622,626,Cytomegalovirus infection,Infections and infestations,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004067,S00221,205,226,Tremor,Nervous system disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004068,S00221,308,319,Cough,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004069,S00221,620,646,Bilirubin increased,Investigations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004070,S00221,192,199,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004071,S00221,203,208,Cytomegalovirus infection,Infections and infestations,3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004072,S00221,206,220,Complement activation,Immune system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004073,S00221,200,203,Tremor,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004074,S00221,485,493,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004075,S00221,43,67,Hypogammaglobulinaemia,Immune system disorders,4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004076,S00221,357,365,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004077,S00221,60,76,Alanine aminotransferase increased,Investigations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004078,S00221,243,244,Alanine aminotransferase increased,Investigations,5,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0004079,S00221,444,452,Tremor,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004080,S00221,706,733,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004081,S00221,419,429,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004082,S00221,308,309,Cytomegalovirus infection,Infections and infestations,4,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004083,S00221,122,126,Seizure,Nervous system disorders,4,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0004084,S00223,8,15,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,3,Y,Y,Corticosteroids,Recovered,N,0,Y,3,N,N,Y
AE0004085,S00223,308,316,Complement activation,Immune system disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004086,S00223,0,21,Sepsis,Infections and infestations,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004087,S00223,715,733,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004088,S00223,173,194,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0004089,S00223,710,719,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004090,S00223,423,432,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0004091,S00223,407,435,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004092,S00223,29,43,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004093,S00223,198,222,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0004094,S00223,410,438,Diarrhoea,Gastrointestinal disorders,1,N,Y,Dose modification,Unknown,N,0,N,0,N,N,N
AE0004095,S00223,371,385,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004096,S00223,149,163,Pyrexia,General disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004097,S00223,509,530,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004098,S00223,196,204,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004099,S00223,15,19,Anaemia,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004100,S00223,222,236,Aspartate aminotransferase increased,Investigations,4,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004101,S00224,662,680,Cough,"Respiratory, thoracic, mediastinal",3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0004102,S00224,144,151,Neutropenia,Blood and lymphatic system,3,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0004103,S00224,272,288,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0004104,S00224,175,188,Aphasia,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004105,S00224,495,515,Anaemia,Blood and lymphatic system,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004106,S00224,531,550,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004107,S00224,59,80,Complement activation,Immune system disorders,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004108,S00224,580,593,Vomiting,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004109,S00224,399,417,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004110,S00224,354,382,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004111,S00224,485,488,Anaemia,Blood and lymphatic system,1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0004112,S00224,204,218,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004113,S00224,461,467,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004114,S00224,302,321,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004115,S00225,460,473,Pyrexia,General disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004116,S00225,664,692,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0004117,S00225,471,475,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0004118,S00225,427,435,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004119,S00225,423,442,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004120,S00225,306,307,Pyrexia,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004121,S00225,57,76,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004122,S00225,80,83,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004123,S00225,672,680,Hypotension,Vascular disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004124,S00225,28,52,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Recovering,N,0,N,0,N,Y,Y
AE0004125,S00225,510,523,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004126,S00225,177,185,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004127,S00225,88,94,Tachycardia,Cardiac disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004128,S00225,308,327,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004129,S00225,530,557,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0004130,S00225,363,368,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,Drug interrupted,Recovered,N,0,N,0,N,Y,Y
AE0004131,S00225,358,366,Diarrhoea,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004132,S00225,673,702,Tremor,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004133,S00225,242,268,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0004134,S00225,261,272,Thrombocytopenia,Blood and lymphatic system,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0004135,S00226,6,9,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0004136,S00226,315,317,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004137,S00226,79,97,Neutropenia,Blood and lymphatic system,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004138,S00226,689,713,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004139,S00226,591,593,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004140,S00226,343,354,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0004141,S00226,505,529,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004142,S00226,170,188,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004143,S00226,474,479,Bilirubin increased,Investigations,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004144,S00226,388,403,Seizure,Nervous system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004145,S00226,340,354,Tremor,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004146,S00226,273,274,Neutropenia,Blood and lymphatic system,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004147,S00226,626,642,Mucosal inflammation,Gastrointestinal disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004148,S00226,422,436,Pyrexia,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004149,S00226,608,631,Neutropenia,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004150,S00226,571,576,Aphasia,Nervous system disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004151,S00226,631,644,Confusional state,Psychiatric disorders,1,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0004152,S00226,505,521,Bilirubin increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004153,S00226,182,207,Pyrexia,General disorders,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004154,S00226,65,79,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004155,S00226,713,732,Neutropenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004156,S00226,163,192,Confusional state,Psychiatric disorders,2,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0004157,S00226,181,204,Aspartate aminotransferase increased,Investigations,4,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004158,S00226,237,260,Infusion related reaction,"Injury, poisoning, procedural",4,N,Y,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0004159,S00228,59,73,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004160,S00228,275,276,Alanine aminotransferase increased,Investigations,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0004161,S00228,327,342,Bilirubin increased,Investigations,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004162,S00228,159,175,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004163,S00228,279,305,Sepsis,Infections and infestations,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004164,S00228,146,149,Thrombotic microangiopathy,Blood and lymphatic system,5,N,N,Drug interrupted,Not recovered,N,0,N,0,N,Y,Y
AE0004165,S00228,266,275,Anaemia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004166,S00228,613,622,Hypotension,Vascular disorders,5,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0004167,S00228,626,636,Vomiting,Gastrointestinal disorders,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004168,S00228,499,510,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0004169,S00228,359,374,Anaemia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004170,S00228,537,539,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004171,S00228,547,557,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004172,S00229,3,20,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0004173,S00229,298,326,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004174,S00229,159,171,Tremor,Nervous system disorders,3,Y,N,None,Recovering,N,0,N,0,N,N,N
AE0004175,S00229,588,603,Bilirubin increased,Investigations,1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0004176,S00229,534,555,Fatigue,General disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004177,S00229,614,640,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,Y,Y
AE0004178,S00229,85,103,Sepsis,Infections and infestations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004179,S00229,213,238,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0004180,S00229,542,544,Mucosal inflammation,Gastrointestinal disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004181,S00229,600,611,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004182,S00229,257,280,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004183,S00229,58,83,Nausea,Gastrointestinal disorders,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004184,S00229,322,340,Vomiting,Gastrointestinal disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004185,S00229,448,449,Sepsis,Infections and infestations,5,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004186,S00229,685,694,Seizure,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004187,S00229,132,138,Fatigue,General disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004188,S00229,291,312,Confusional state,Psychiatric disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004189,S00229,142,171,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0004190,S00229,648,667,Thrombocytopenia,Blood and lymphatic system,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004191,S00229,266,277,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0004192,S00229,301,324,Sepsis,Infections and infestations,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004193,S00229,145,161,Cytomegalovirus infection,Infections and infestations,3,N,Y,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0004194,S00229,36,57,Diarrhoea,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004195,S00229,273,301,Anaemia,Blood and lymphatic system,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004196,S00229,358,363,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004197,S00229,348,358,Seizure,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004198,S00229,327,346,Aphasia,Nervous system disorders,5,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004199,S00229,273,289,Bilirubin increased,Investigations,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004200,S00229,290,302,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004201,S00229,391,410,Seizure,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004202,S00229,51,64,Tremor,Nervous system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004203,S00229,184,206,Neutropenia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004204,S00229,266,295,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004205,S00229,263,279,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004206,S00229,349,354,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004207,S00231,315,329,Tachycardia,Cardiac disorders,2,N,Y,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0004208,S00231,214,216,Complement activation,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004209,S00231,286,308,Alanine aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004210,S00231,729,744,Fatigue,General disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004211,S00231,618,621,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004212,S00231,110,139,Pyrexia,General disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004213,S00231,271,282,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004214,S00231,546,571,Fatigue,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004215,S00231,202,210,Aphasia,Nervous system disorders,2,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0004216,S00231,418,434,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004217,S00231,522,535,Complement activation,Immune system disorders,1,N,N,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0004218,S00231,579,603,Anaemia,Blood and lymphatic system,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004219,S00233,282,303,Seizure,Nervous system disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004220,S00233,501,515,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004221,S00233,249,272,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004222,S00233,196,217,Hypotension,Vascular disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004223,S00233,614,631,Aspartate aminotransferase increased,Investigations,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004224,S00233,84,107,Pyrexia,General disorders,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0004225,S00233,377,393,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004226,S00233,640,663,Fatigue,General disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004227,S00233,506,507,Alanine aminotransferase increased,Investigations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004228,S00233,636,649,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004229,S00233,190,213,Vomiting,Gastrointestinal disorders,1,N,Y,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0004230,S00233,568,590,Aspartate aminotransferase increased,Investigations,4,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004231,S00233,0,26,Bilirubin increased,Investigations,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004232,S00233,354,379,Thrombocytopenia,Blood and lymphatic system,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004233,S00233,461,475,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004234,S00234,402,422,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0004235,S00234,100,107,Neutropenia,Blood and lymphatic system,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004236,S00234,266,271,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004237,S00234,415,427,Hypotension,Vascular disorders,4,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0004238,S00234,103,115,Neutropenia,Blood and lymphatic system,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004239,S00234,441,456,Seizure,Nervous system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004240,S00234,123,132,Headache,Nervous system disorders,4,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004241,S00234,489,518,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004242,S00234,66,92,Thrombocytopenia,Blood and lymphatic system,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004243,S00234,572,597,Tachycardia,Cardiac disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004244,S00234,194,213,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004245,S00235,4,13,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0004246,S00235,251,279,Neutropenia,Blood and lymphatic system,3,Y,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0004247,S00235,84,95,Neutropenia,Blood and lymphatic system,3,Y,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004248,S00235,142,165,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004249,S00235,649,672,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004250,S00235,17,25,Aphasia,Nervous system disorders,5,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004251,S00235,651,658,Tremor,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004252,S00235,319,333,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004253,S00235,503,523,Seizure,Nervous system disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004254,S00235,320,343,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004255,S00235,215,239,Seizure,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004256,S00235,405,412,Neutropenia,Blood and lymphatic system,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004257,S00235,664,675,Nausea,Gastrointestinal disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004258,S00235,199,210,Confusional state,Psychiatric disorders,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0004259,S00235,482,498,Fatigue,General disorders,1,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0004260,S00235,396,407,Complement activation,Immune system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004261,S00235,676,688,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004262,S00235,526,536,Cytomegalovirus infection,Infections and infestations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004263,S00235,370,375,Alanine aminotransferase increased,Investigations,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004264,S00235,136,161,Vomiting,Gastrointestinal disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004265,S00235,524,544,Pyrexia,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004266,S00235,382,391,Nausea,Gastrointestinal disorders,1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0004267,S00235,469,494,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004268,S00235,197,222,Diarrhoea,Gastrointestinal disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004269,S00236,4,20,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0004270,S00236,606,628,Anaemia,Blood and lymphatic system,3,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0004271,S00236,557,563,Pyrexia,General disorders,1,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0004272,S00236,57,83,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004273,S00236,102,112,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004274,S00236,628,648,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004275,S00236,312,335,Aphasia,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004276,S00236,249,258,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004277,S00236,319,341,Headache,Nervous system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004278,S00236,580,593,Bilirubin increased,Investigations,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004279,S00236,304,323,Tremor,Nervous system disorders,1,N,N,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0004280,S00236,85,88,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0004281,S00236,6,34,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004282,S00236,41,57,Complement activation,Immune system disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004283,S00236,170,183,Hypotension,Vascular disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004284,S00236,551,558,Confusional state,Psychiatric disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004285,S00236,397,416,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004286,S00236,658,667,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004287,S00236,660,666,Aphasia,Nervous system disorders,4,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004288,S00236,236,261,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004289,S00236,631,633,Diarrhoea,Gastrointestinal disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004290,S00236,118,126,Bilirubin increased,Investigations,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004291,S00236,649,652,Sepsis,Infections and infestations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004292,S00236,310,321,Cytomegalovirus infection,Infections and infestations,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004293,S00236,291,319,Aphasia,Nervous system disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004294,S00236,315,323,Bilirubin increased,Investigations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004295,S00236,295,323,Bilirubin increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004296,S00236,634,660,Anaemia,Blood and lymphatic system,4,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0004297,S00236,163,180,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004298,S00236,411,416,Hypogammaglobulinaemia,Immune system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004299,S00236,306,311,Aphasia,Nervous system disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004300,S00236,707,723,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004301,S00236,41,55,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004302,S00236,127,132,Headache,Nervous system disorders,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004303,S00238,2,21,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0004304,S00238,10,19,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,3,Y,Y,Corticosteroids,Recovered,N,0,Y,3,N,N,Y
AE0004305,S00238,536,539,Confusional state,Psychiatric disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004306,S00238,525,554,Neutropenia,Blood and lymphatic system,5,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004307,S00238,157,184,Fatigue,General disorders,5,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004308,S00238,350,363,Nausea,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004309,S00238,356,370,Mucosal inflammation,Gastrointestinal disorders,5,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004310,S00238,416,426,Pyrexia,General disorders,2,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0004311,S00238,403,418,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004312,S00238,473,490,Hypotension,Vascular disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004313,S00238,705,720,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004314,S00238,542,556,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004315,S00238,201,224,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004316,S00238,43,53,Pyrexia,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004317,S00238,7,22,Neutropenia,Blood and lymphatic system,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004318,S00238,136,155,Bilirubin increased,Investigations,3,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0004319,S00238,334,357,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004320,S00238,82,88,Bilirubin increased,Investigations,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0004321,S00238,438,458,Alanine aminotransferase increased,Investigations,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004322,S00238,318,342,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004323,S00238,581,583,Anaemia,Blood and lymphatic system,2,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0004324,S00238,349,372,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004325,S00238,308,333,Sepsis,Infections and infestations,4,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004326,S00238,437,449,Neutropenia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004327,S00238,446,475,Anaemia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004328,S00238,38,54,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004329,S00238,39,54,Headache,Nervous system disorders,2,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0004330,S00238,650,656,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004331,S00238,178,197,Fatigue,General disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004332,S00238,579,594,Alanine aminotransferase increased,Investigations,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004333,S00239,424,453,Tremor,Nervous system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004334,S00239,668,684,Hypotension,Vascular disorders,3,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004335,S00239,295,297,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004336,S00239,504,505,Anaemia,Blood and lymphatic system,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004337,S00239,467,475,Fatigue,General disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004338,S00239,174,177,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004339,S00239,32,48,Pyrexia,General disorders,2,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0004340,S00239,268,271,Sepsis,Infections and infestations,4,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004341,S00239,350,376,Aphasia,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004342,S00239,210,225,Confusional state,Psychiatric disorders,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0004343,S00240,212,218,Thrombocytopenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004344,S00240,487,512,Confusional state,Psychiatric disorders,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004345,S00240,518,547,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0004346,S00240,466,484,Alanine aminotransferase increased,Investigations,3,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0004347,S00240,188,193,Sepsis,Infections and infestations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004348,S00240,322,342,Diarrhoea,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0004349,S00240,198,219,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0004350,S00240,685,713,Hypogammaglobulinaemia,Immune system disorders,3,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004351,S00240,256,273,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0004352,S00240,44,61,Bilirubin increased,Investigations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004353,S00240,423,433,Anaemia,Blood and lymphatic system,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004354,S00240,561,586,Cytomegalovirus infection,Infections and infestations,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004355,S00241,6,20,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0004356,S00241,7,9,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0004357,S00241,447,454,Seizure,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004358,S00241,427,451,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004359,S00241,695,723,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0004360,S00241,301,315,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004361,S00241,563,591,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004362,S00241,140,153,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0004363,S00241,57,76,Sepsis,Infections and infestations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004364,S00241,146,148,Bilirubin increased,Investigations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004365,S00241,48,73,Tachycardia,Cardiac disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004366,S00241,550,572,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0004367,S00241,591,615,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004368,S00241,673,676,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004369,S00241,421,440,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004370,S00241,184,212,Mucosal inflammation,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004371,S00241,291,304,Seizure,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004372,S00241,39,41,Cytomegalovirus infection,Infections and infestations,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004373,S00241,535,541,Hypotension,Vascular disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004374,S00241,515,536,Headache,Nervous system disorders,1,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0004375,S00241,611,634,Sepsis,Infections and infestations,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004376,S00241,235,246,Infusion related reaction,"Injury, poisoning, procedural",4,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004377,S00241,1,19,Confusional state,Psychiatric disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004378,S00241,568,585,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0004379,S00241,237,250,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004380,S00242,2,6,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0004381,S00242,3,10,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0004382,S00242,161,166,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004383,S00242,120,133,Seizure,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004384,S00242,455,475,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004385,S00242,390,418,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004386,S00242,403,407,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004387,S00242,370,392,Confusional state,Psychiatric disorders,3,Y,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004388,S00242,379,395,Aphasia,Nervous system disorders,3,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004389,S00242,86,101,Neutropenia,Blood and lymphatic system,3,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004390,S00242,131,155,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004391,S00242,192,207,Complement activation,Immune system disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004392,S00242,48,53,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004393,S00242,470,498,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004394,S00242,345,364,Sepsis,Infections and infestations,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004395,S00242,293,315,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004396,S00242,291,292,Alanine aminotransferase increased,Investigations,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004397,S00242,264,290,Hypotension,Vascular disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004398,S00242,537,562,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004399,S00242,17,20,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,None,Fatal,N,0,N,0,N,Y,Y
AE0004400,S00242,705,721,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004401,S00242,487,490,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0004402,S00242,485,498,Tachycardia,Cardiac disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004403,S00242,208,211,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004404,S00243,724,750,Thrombocytopenia,Blood and lymphatic system,3,Y,N,None,Recovering,N,0,N,0,N,N,N
AE0004405,S00243,72,98,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004406,S00243,509,519,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0004407,S00243,91,106,Bilirubin increased,Investigations,3,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004408,S00243,178,179,Fatigue,General disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004409,S00243,152,168,Sepsis,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004410,S00243,278,298,Cough,"Respiratory, thoracic, mediastinal",2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0004411,S00243,135,144,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004412,S00243,324,348,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004413,S00243,414,435,Bilirubin increased,Investigations,1,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0004414,S00243,468,474,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004415,S00243,68,93,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004416,S00243,726,738,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0004417,S00243,145,164,Tachycardia,Cardiac disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004418,S00243,517,540,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004419,S00243,413,431,Seizure,Nervous system disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004420,S00243,106,123,Hypogammaglobulinaemia,Immune system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004421,S00244,513,522,Cough,"Respiratory, thoracic, mediastinal",3,Y,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004422,S00244,609,625,Vomiting,Gastrointestinal disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004423,S00244,657,661,Cytomegalovirus infection,Infections and infestations,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004424,S00244,330,340,Sepsis,Infections and infestations,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004425,S00244,95,96,Complement activation,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004426,S00244,254,275,Infusion related reaction,"Injury, poisoning, procedural",3,Y,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004427,S00244,565,589,Complement activation,Immune system disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004428,S00244,80,108,Aspartate aminotransferase increased,Investigations,2,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0004429,S00244,690,716,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004430,S00245,325,350,Nausea,Gastrointestinal disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004431,S00245,376,383,Cough,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004432,S00245,401,417,Neutropenia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004433,S00245,55,69,Anaemia,Blood and lymphatic system,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004434,S00245,470,478,Sepsis,Infections and infestations,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004435,S00245,543,569,Complement activation,Immune system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004436,S00245,84,107,Tachycardia,Cardiac disorders,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004437,S00245,138,145,Headache,Nervous system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004438,S00245,30,33,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004439,S00246,1,13,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0004440,S00246,9,24,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,2,N,Y,Corticosteroids,Recovered,N,0,Y,2,N,N,Y
AE0004441,S00246,207,215,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004442,S00246,363,391,Complement activation,Immune system disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0004443,S00246,283,308,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004444,S00246,112,113,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004445,S00246,343,363,Seizure,Nervous system disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004446,S00246,354,370,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004447,S00246,97,107,Sepsis,Infections and infestations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004448,S00246,20,46,Diarrhoea,Gastrointestinal disorders,5,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004449,S00246,713,717,Complement activation,Immune system disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004450,S00246,284,309,Alanine aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004451,S00246,670,699,Fatigue,General disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004452,S00246,464,485,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004453,S00246,653,673,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004454,S00246,172,176,Sepsis,Infections and infestations,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004455,S00246,313,328,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004456,S00246,60,68,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004457,S00246,195,218,Bilirubin increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004458,S00246,132,159,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004459,S00246,654,674,Pyrexia,General disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004460,S00246,286,310,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,None,Not recovered,N,0,N,0,N,Y,Y
AE0004461,S00246,136,162,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004462,S00246,653,679,Sepsis,Infections and infestations,2,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0004463,S00246,230,249,Hypotension,Vascular disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004464,S00246,680,684,Complement activation,Immune system disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004465,S00246,606,625,Fatigue,General disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004466,S00246,209,232,Confusional state,Psychiatric disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004467,S00246,198,204,Pyrexia,General disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004468,S00246,349,367,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0004469,S00246,409,415,Thrombocytopenia,Blood and lymphatic system,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004470,S00246,222,249,Tachycardia,Cardiac disorders,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004471,S00246,481,508,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004472,S00247,478,489,Vomiting,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004473,S00247,282,296,Cytomegalovirus infection,Infections and infestations,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004474,S00247,271,284,Anaemia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004475,S00247,328,344,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004476,S00247,298,307,Seizure,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004477,S00247,243,267,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004478,S00247,252,280,Nausea,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004479,S00247,585,603,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004480,S00249,83,101,Seizure,Nervous system disorders,5,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004481,S00249,474,487,Bilirubin increased,Investigations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004482,S00249,726,745,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0004483,S00249,484,498,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004484,S00249,391,413,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004485,S00249,89,114,Nausea,Gastrointestinal disorders,2,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0004486,S00249,359,378,Complement activation,Immune system disorders,5,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004487,S00249,601,603,Hypotension,Vascular disorders,5,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004488,S00249,350,367,Sepsis,Infections and infestations,2,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0004489,S00249,145,163,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004490,S00249,549,556,Nausea,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0004491,S00249,661,680,Tachycardia,Cardiac disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004492,S00249,246,267,Confusional state,Psychiatric disorders,3,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0004493,S00249,619,632,Hypotension,Vascular disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004494,S00251,3,6,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0004495,S00251,253,258,Mucosal inflammation,Gastrointestinal disorders,3,Y,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004496,S00251,289,297,Alanine aminotransferase increased,Investigations,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004497,S00251,431,460,Aphasia,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004498,S00251,723,728,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,Y,Y
AE0004499,S00251,723,738,Hypotension,Vascular disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004500,S00251,570,578,Vomiting,Gastrointestinal disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004501,S00251,228,242,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004502,S00251,630,641,Sepsis,Infections and infestations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004503,S00251,389,390,Pyrexia,General disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004504,S00251,326,327,Tachycardia,Cardiac disorders,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0004505,S00251,360,364,Neutropenia,Blood and lymphatic system,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004506,S00251,348,352,Sepsis,Infections and infestations,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004507,S00251,347,359,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004508,S00251,76,98,Anaemia,Blood and lymphatic system,2,N,N,Dose modification,Unknown,N,0,N,0,N,N,N
AE0004509,S00251,350,376,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004510,S00251,349,352,Pyrexia,General disorders,1,N,Y,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0004511,S00251,85,89,Tremor,Nervous system disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0004512,S00251,207,222,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004513,S00251,47,72,Fatigue,General disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004514,S00251,267,292,Aphasia,Nervous system disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004515,S00251,715,721,Alanine aminotransferase increased,Investigations,3,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004516,S00251,466,481,Cytomegalovirus infection,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004517,S00251,48,49,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0004518,S00251,583,602,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004519,S00251,369,388,Nausea,Gastrointestinal disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004520,S00251,496,508,Sepsis,Infections and infestations,3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004521,S00251,667,694,Aphasia,Nervous system disorders,4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004522,S00251,281,298,Diarrhoea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0004523,S00251,354,357,Pyrexia,General disorders,4,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004524,S00251,719,724,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,Y,Y
AE0004525,S00252,491,518,Hypoxia,"Respiratory, thoracic, mediastinal",3,Y,Y,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0004526,S00252,160,189,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004527,S00252,247,252,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004528,S00252,49,55,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004529,S00252,655,666,Aphasia,Nervous system disorders,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004530,S00252,70,78,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004531,S00252,569,593,Headache,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004532,S00252,698,726,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004533,S00252,599,613,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004534,S00252,710,725,Headache,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004535,S00252,678,687,Neutropenia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004536,S00252,5,19,Headache,Nervous system disorders,3,N,N,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0004537,S00252,626,653,Hypotension,Vascular disorders,3,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004538,S00252,42,49,Hypoxia,"Respiratory, thoracic, mediastinal",5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004539,S00252,3,29,Tremor,Nervous system disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004540,S00252,650,673,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004541,S00252,635,655,Neutropenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004542,S00252,202,206,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004543,S00252,477,492,Anaemia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004544,S00252,82,86,Aspartate aminotransferase increased,Investigations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004545,S00252,619,622,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004546,S00252,274,278,Nausea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004547,S00252,269,278,Headache,Nervous system disorders,1,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0004548,S00252,55,65,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004549,S00252,522,541,Bilirubin increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004550,S00252,670,684,Tachycardia,Cardiac disorders,1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0004551,S00252,37,47,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004552,S00252,673,699,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004553,S00253,37,52,Hepatocellular injury,Hepatobiliary disorders,3,Y,Y,Tocilizumab,Recovered,Y,0,N,0,Y,N,Y
AE0004554,S00253,447,476,Alanine aminotransferase increased,Investigations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004555,S00253,331,339,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0004556,S00253,504,513,Pyrexia,General disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004557,S00253,641,646,Complement activation,Immune system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004558,S00253,350,359,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Dose modification,Recovering,N,0,N,0,N,Y,Y
AE0004559,S00253,355,369,Vomiting,Gastrointestinal disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004560,S00253,184,196,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004561,S00253,392,407,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004562,S00253,484,493,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004563,S00253,486,510,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004564,S00254,240,263,Nausea,Gastrointestinal disorders,2,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0004565,S00254,536,540,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004566,S00254,286,297,Anaemia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004567,S00254,651,661,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004568,S00254,204,215,Tremor,Nervous system disorders,3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004569,S00254,227,233,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004570,S00254,405,414,Nausea,Gastrointestinal disorders,3,Y,N,None,Recovering,N,0,N,0,N,N,N
AE0004571,S00254,501,527,Tachycardia,Cardiac disorders,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004572,S00254,522,546,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0004573,S00254,561,570,Seizure,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004574,S00254,604,631,Sepsis,Infections and infestations,5,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004575,S00254,460,461,Bilirubin increased,Investigations,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004576,S00254,118,136,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004577,S00254,74,81,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004578,S00254,325,354,Nausea,Gastrointestinal disorders,3,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004579,S00254,672,678,Thrombocytopenia,Blood and lymphatic system,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004580,S00254,481,506,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,Drug interrupted,Unknown,N,0,N,0,N,Y,Y
AE0004581,S00255,86,103,Sepsis,Infections and infestations,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004582,S00255,108,120,Tremor,Nervous system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004583,S00255,374,392,Fatigue,General disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004584,S00255,388,407,Pyrexia,General disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004585,S00255,15,30,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004586,S00255,122,126,Seizure,Nervous system disorders,3,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004587,S00255,635,644,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004588,S00255,288,314,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004589,S00255,299,305,Headache,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004590,S00255,167,182,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004591,S00255,642,651,Nausea,Gastrointestinal disorders,3,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004592,S00255,560,569,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004593,S00255,402,421,Vomiting,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004594,S00255,521,545,Aphasia,Nervous system disorders,1,N,Y,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0004595,S00255,233,247,Neutropenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004596,S00255,711,720,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004597,S00255,517,546,Bilirubin increased,Investigations,3,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004598,S00255,409,417,Sepsis,Infections and infestations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004599,S00255,321,331,Cytomegalovirus infection,Infections and infestations,1,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0004600,S00256,7,21,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0004601,S00256,8,25,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0004602,S00256,351,365,Aphasia,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004603,S00256,424,443,Alanine aminotransferase increased,Investigations,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0004604,S00256,699,722,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004605,S00256,656,683,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004606,S00256,303,306,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004607,S00256,525,541,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0004608,S00256,664,667,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004609,S00256,82,92,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004610,S00256,410,430,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004611,S00256,620,628,Fatigue,General disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004612,S00256,166,183,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004613,S00256,249,263,Neutropenia,Blood and lymphatic system,3,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004614,S00256,226,234,Mucosal inflammation,Gastrointestinal disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004615,S00256,423,450,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004616,S00256,617,625,Anaemia,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004617,S00256,438,467,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004618,S00256,106,127,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004619,S00256,157,185,Tremor,Nervous system disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004620,S00256,712,718,Alanine aminotransferase increased,Investigations,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004621,S00256,614,638,Diarrhoea,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004622,S00256,25,37,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004623,S00256,577,596,Alanine aminotransferase increased,Investigations,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004624,S00256,65,79,Seizure,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004625,S00256,227,255,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004626,S00256,26,35,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004627,S00256,16,23,Anaemia,Blood and lymphatic system,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004628,S00256,77,86,Aspartate aminotransferase increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004629,S00257,5,14,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0004630,S00257,108,137,Aphasia,Nervous system disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004631,S00257,344,361,Neutropenia,Blood and lymphatic system,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004632,S00257,289,311,Aspartate aminotransferase increased,Investigations,3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004633,S00257,626,653,Nausea,Gastrointestinal disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004634,S00257,344,367,Aspartate aminotransferase increased,Investigations,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004635,S00257,151,152,Tremor,Nervous system disorders,3,Y,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004636,S00257,665,675,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004637,S00257,72,94,Hypogammaglobulinaemia,Immune system disorders,3,Y,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004638,S00257,59,66,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004639,S00257,454,480,Bilirubin increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004640,S00257,323,349,Bilirubin increased,Investigations,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004641,S00257,369,379,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004642,S00257,501,504,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004643,S00257,391,419,Tachycardia,Cardiac disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004644,S00257,645,646,Complement activation,Immune system disorders,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0004645,S00257,365,386,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004646,S00257,146,174,Aspartate aminotransferase increased,Investigations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004647,S00257,471,500,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004648,S00257,485,488,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004649,S00257,200,215,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004650,S00257,641,657,Cytomegalovirus infection,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004651,S00257,47,62,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004652,S00257,192,208,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004653,S00257,294,313,Sepsis,Infections and infestations,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004654,S00257,616,645,Cough,"Respiratory, thoracic, mediastinal",2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004655,S00257,429,450,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004656,S00257,265,273,Seizure,Nervous system disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004657,S00259,452,462,Mucosal inflammation,Gastrointestinal disorders,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0004658,S00259,2,11,Hypotension,Vascular disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0004659,S00259,700,715,Hypotension,Vascular disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004660,S00259,319,334,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004661,S00259,572,579,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004662,S00259,472,485,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004663,S00259,353,375,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004664,S00259,376,378,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Recovering,N,0,N,0,N,Y,Y
AE0004665,S00259,626,645,Thrombocytopenia,Blood and lymphatic system,3,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0004666,S00259,72,98,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0004667,S00259,356,380,Cytomegalovirus infection,Infections and infestations,3,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0004668,S00259,341,370,Alanine aminotransferase increased,Investigations,1,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0004669,S00259,535,550,Cough,"Respiratory, thoracic, mediastinal",4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004670,S00259,259,275,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004671,S00259,259,273,Pyrexia,General disorders,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0004672,S00259,562,587,Bilirubin increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004673,S00260,154,180,Aphasia,Nervous system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004674,S00260,407,408,Pyrexia,General disorders,3,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0004675,S00260,515,516,Aphasia,Nervous system disorders,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004676,S00260,2,4,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004677,S00260,137,140,Confusional state,Psychiatric disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004678,S00261,595,601,Headache,Nervous system disorders,2,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0004679,S00261,619,624,Pyrexia,General disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004680,S00261,451,471,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004681,S00261,403,430,Bilirubin increased,Investigations,5,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004682,S00261,269,276,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004683,S00261,233,262,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0004684,S00261,150,159,Neutropenia,Blood and lymphatic system,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0004685,S00261,263,277,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0004686,S00261,117,145,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004687,S00261,208,213,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004688,S00261,523,551,Aspartate aminotransferase increased,Investigations,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0004689,S00261,220,224,Fatigue,General disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004690,S00261,645,647,Hypotension,Vascular disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004691,S00262,322,337,Alanine aminotransferase increased,Investigations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004692,S00262,67,80,Cytomegalovirus infection,Infections and infestations,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004693,S00262,35,46,Headache,Nervous system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004694,S00262,375,390,Vomiting,Gastrointestinal disorders,4,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004695,S00262,683,705,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Recovering,N,0,N,0,N,Y,Y
AE0004696,S00262,212,236,Thrombocytopenia,Blood and lymphatic system,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004697,S00262,662,673,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004698,S00262,6,22,Neutropenia,Blood and lymphatic system,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004699,S00262,414,423,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004700,S00262,383,406,Thrombocytopenia,Blood and lymphatic system,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004701,S00262,256,275,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004702,S00262,209,237,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004703,S00262,654,663,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004704,S00262,703,722,Aspartate aminotransferase increased,Investigations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004705,S00262,571,594,Alanine aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0004706,S00262,408,432,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004707,S00262,277,291,Hypotension,Vascular disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004708,S00262,505,528,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004709,S00262,145,163,Thrombocytopenia,Blood and lymphatic system,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004710,S00262,562,587,Tachycardia,Cardiac disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004711,S00262,507,515,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004712,S00262,658,661,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004713,S00262,418,430,Aphasia,Nervous system disorders,3,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0004714,S00262,620,627,Nausea,Gastrointestinal disorders,1,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0004715,S00262,429,454,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004716,S00262,512,533,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004717,S00262,728,729,Neutropenia,Blood and lymphatic system,2,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0004718,S00262,420,448,Tremor,Nervous system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004719,S00262,351,373,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004720,S00262,320,349,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,None,Not recovered,N,0,N,0,N,Y,Y
AE0004721,S00262,135,160,Confusional state,Psychiatric disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004722,S00262,601,625,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0004723,S00262,78,83,Hypotension,Vascular disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004724,S00262,197,224,Aspartate aminotransferase increased,Investigations,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0004725,S00262,247,276,Anaemia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004726,S00262,674,699,Headache,Nervous system disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004727,S00262,457,472,Hypotension,Vascular disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004728,S00262,278,290,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004729,S00263,618,626,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004730,S00263,678,687,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004731,S00263,287,296,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,None,Recovering,N,0,N,0,N,Y,Y
AE0004732,S00263,292,312,Seizure,Nervous system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004733,S00263,175,192,Anaemia,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004734,S00263,38,58,Tachycardia,Cardiac disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004735,S00263,527,553,Thrombocytopenia,Blood and lymphatic system,5,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0004736,S00263,251,262,Aphasia,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004737,S00263,601,622,Aphasia,Nervous system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004738,S00263,271,295,Bilirubin increased,Investigations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004739,S00263,700,721,Neutropenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004740,S00263,459,478,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004741,S00263,471,491,Anaemia,Blood and lymphatic system,1,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0004742,S00263,325,330,Anaemia,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004743,S00263,556,563,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004744,S00263,571,580,Complement activation,Immune system disorders,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004745,S00263,643,654,Aphasia,Nervous system disorders,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0004746,S00263,84,97,Nausea,Gastrointestinal disorders,1,N,Y,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0004747,S00264,475,494,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004748,S00264,521,534,Vomiting,Gastrointestinal disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0004749,S00264,185,209,Bilirubin increased,Investigations,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0004750,S00264,562,581,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004751,S00264,62,87,Aphasia,Nervous system disorders,5,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004752,S00264,441,463,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004753,S00264,271,273,Seizure,Nervous system disorders,5,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004754,S00264,278,294,Pyrexia,General disorders,3,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004755,S00264,322,331,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004756,S00265,1,14,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0004757,S00265,130,137,Pyrexia,General disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004758,S00265,291,294,Anaemia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004759,S00265,48,77,Thrombocytopenia,Blood and lymphatic system,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004760,S00265,158,180,Thrombocytopenia,Blood and lymphatic system,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004761,S00265,142,161,Alanine aminotransferase increased,Investigations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004762,S00265,369,391,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004763,S00265,380,404,Mucosal inflammation,Gastrointestinal disorders,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004764,S00265,174,191,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004765,S00265,725,752,Hypoxia,"Respiratory, thoracic, mediastinal",5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004766,S00265,611,631,Diarrhoea,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0004767,S00265,146,148,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004768,S00265,331,358,Aphasia,Nervous system disorders,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004769,S00265,66,69,Pyrexia,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004770,S00265,641,661,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004771,S00265,202,222,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004772,S00265,163,173,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004773,S00265,123,139,Bilirubin increased,Investigations,5,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004774,S00265,98,112,Diarrhoea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0004775,S00265,665,680,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004776,S00265,427,433,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004777,S00265,569,571,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004778,S00265,662,672,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0004779,S00265,133,158,Pyrexia,General disorders,2,N,N,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0004780,S00265,558,560,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0004781,S00265,199,219,Sepsis,Infections and infestations,1,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0004782,S00265,157,186,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004783,S00265,52,71,Nausea,Gastrointestinal disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004784,S00265,686,705,Seizure,Nervous system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004785,S00265,483,502,Anaemia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004786,S00265,52,65,Infusion related reaction,"Injury, poisoning, procedural",5,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004787,S00265,728,741,Aphasia,Nervous system disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004788,S00265,148,171,Bilirubin increased,Investigations,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004789,S00265,499,510,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004790,S00265,184,200,Sepsis,Infections and infestations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004791,S00266,613,628,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004792,S00266,218,243,Sepsis,Infections and infestations,3,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004793,S00266,92,103,Cough,"Respiratory, thoracic, mediastinal",2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004794,S00266,459,469,Neutropenia,Blood and lymphatic system,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004795,S00266,298,326,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004796,S00266,418,422,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004797,S00266,146,167,Anaemia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004798,S00266,215,224,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004799,S00266,101,125,Aphasia,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004800,S00266,163,188,Cytomegalovirus infection,Infections and infestations,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004801,S00267,48,62,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004802,S00267,139,165,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004803,S00267,86,113,Headache,Nervous system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004804,S00267,626,641,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004805,S00267,306,332,Confusional state,Psychiatric disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004806,S00267,70,99,Aspartate aminotransferase increased,Investigations,3,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0004807,S00267,320,343,Sepsis,Infections and infestations,5,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0004808,S00267,328,346,Anaemia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004809,S00267,633,639,Bilirubin increased,Investigations,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004810,S00267,524,539,Complement activation,Immune system disorders,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004811,S00267,584,594,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004812,S00267,33,55,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004813,S00267,428,436,Complement activation,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004814,S00267,569,576,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004815,S00267,131,155,Pyrexia,General disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004816,S00267,246,261,Anaemia,Blood and lymphatic system,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0004817,S00267,15,21,Confusional state,Psychiatric disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004818,S00267,30,44,Confusional state,Psychiatric disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004819,S00267,519,534,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004820,S00267,102,114,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0004821,S00267,237,243,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004822,S00267,671,689,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004823,S00270,351,356,Pyrexia,General disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004824,S00270,92,116,Sepsis,Infections and infestations,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004825,S00270,640,648,Seizure,Nervous system disorders,4,Y,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0004826,S00270,549,554,Sepsis,Infections and infestations,3,Y,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004827,S00272,162,174,Bilirubin increased,Investigations,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004828,S00272,361,390,Diarrhoea,Gastrointestinal disorders,2,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004829,S00272,190,191,Tachycardia,Cardiac disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0004830,S00272,713,732,Bilirubin increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004831,S00272,391,414,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0004832,S00272,722,723,Cytomegalovirus infection,Infections and infestations,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004833,S00272,148,152,Fatigue,General disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004834,S00272,639,643,Pyrexia,General disorders,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004835,S00272,384,411,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004836,S00273,11,14,Sepsis,Infections and infestations,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004837,S00273,523,533,Pyrexia,General disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004838,S00273,504,522,Pyrexia,General disorders,2,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0004839,S00273,11,15,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004840,S00273,575,594,Hypotension,Vascular disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004841,S00273,113,117,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004842,S00273,78,82,Thrombocytopenia,Blood and lymphatic system,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004843,S00273,541,549,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0004844,S00273,407,426,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004845,S00274,384,405,Seizure,Nervous system disorders,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0004846,S00274,703,712,Anaemia,Blood and lymphatic system,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004847,S00274,433,436,Complement activation,Immune system disorders,5,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0004848,S00274,322,337,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004849,S00274,678,683,Headache,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004850,S00274,210,223,Bilirubin increased,Investigations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004851,S00274,460,480,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,Y,Y
AE0004852,S00274,479,496,Fatigue,General disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004853,S00274,306,318,Complement activation,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004854,S00274,466,467,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004855,S00275,4,11,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0004856,S00275,622,623,Sepsis,Infections and infestations,3,Y,N,None,Fatal,N,0,N,0,N,N,N
AE0004857,S00275,49,78,Aphasia,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004858,S00275,306,325,Anaemia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004859,S00275,112,136,Hypoxia,"Respiratory, thoracic, mediastinal",5,Y,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004860,S00275,624,652,Fatigue,General disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004861,S00275,26,45,Neutropenia,Blood and lymphatic system,3,Y,N,None,Recovering,N,0,N,0,N,N,N
AE0004862,S00275,653,678,Confusional state,Psychiatric disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004863,S00275,559,561,Alanine aminotransferase increased,Investigations,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004864,S00275,616,625,Aphasia,Nervous system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004865,S00275,37,54,Sepsis,Infections and infestations,5,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004866,S00275,498,503,Sepsis,Infections and infestations,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004867,S00275,375,404,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,Y,Y
AE0004868,S00275,205,219,Fatigue,General disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004869,S00275,398,419,Confusional state,Psychiatric disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004870,S00275,425,437,Tremor,Nervous system disorders,1,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0004871,S00275,122,138,Sepsis,Infections and infestations,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004872,S00275,314,318,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004873,S00275,637,661,Tremor,Nervous system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004874,S00275,274,284,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004875,S00275,405,415,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004876,S00275,50,61,Tachycardia,Cardiac disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004877,S00275,668,685,Cough,"Respiratory, thoracic, mediastinal",4,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004878,S00275,240,266,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004879,S00275,314,333,Headache,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004880,S00275,280,304,Pyrexia,General disorders,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0004881,S00275,510,525,Pyrexia,General disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004882,S00275,119,137,Anaemia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004883,S00275,401,415,Neutropenia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004884,S00275,429,442,Hypotension,Vascular disorders,1,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0004885,S00275,229,240,Pyrexia,General disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004886,S00275,697,704,Neutropenia,Blood and lymphatic system,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004887,S00276,24,29,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004888,S00276,659,688,Thrombocytopenia,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004889,S00276,678,682,Fatigue,General disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004890,S00276,396,422,Hypotension,Vascular disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004891,S00276,531,542,Mucosal inflammation,Gastrointestinal disorders,2,N,N,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0004892,S00276,462,490,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004893,S00276,430,445,Headache,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004894,S00276,402,422,Alanine aminotransferase increased,Investigations,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004895,S00276,178,206,Anaemia,Blood and lymphatic system,5,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0004896,S00276,115,124,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004897,S00276,422,427,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004898,S00276,545,558,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0004899,S00276,623,640,Cytomegalovirus infection,Infections and infestations,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004900,S00276,464,485,Confusional state,Psychiatric disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004901,S00276,276,288,Bilirubin increased,Investigations,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004902,S00276,692,701,Vomiting,Gastrointestinal disorders,3,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004903,S00276,409,420,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004904,S00276,351,368,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004905,S00276,496,513,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004906,S00276,408,428,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004907,S00276,581,607,Fatigue,General disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004908,S00276,0,25,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004909,S00276,710,732,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004910,S00276,678,705,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004911,S00276,354,374,Hypotension,Vascular disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004912,S00276,287,302,Neutropenia,Blood and lymphatic system,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004913,S00276,47,49,Complement activation,Immune system disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004914,S00277,555,584,Tremor,Nervous system disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004915,S00277,302,326,Diarrhoea,Gastrointestinal disorders,1,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0004916,S00277,60,68,Thrombocytopenia,Blood and lymphatic system,5,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0004917,S00277,170,181,Aphasia,Nervous system disorders,4,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004918,S00277,23,32,Confusional state,Psychiatric disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004919,S00277,18,42,Neutropenia,Blood and lymphatic system,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004920,S00277,159,183,Nausea,Gastrointestinal disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0004921,S00277,140,152,Mucosal inflammation,Gastrointestinal disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004922,S00277,654,655,Nausea,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004923,S00277,684,693,Tachycardia,Cardiac disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004924,S00277,358,369,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004925,S00277,334,339,Cough,"Respiratory, thoracic, mediastinal",5,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004926,S00277,611,639,Seizure,Nervous system disorders,5,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0004927,S00277,92,105,Diarrhoea,Gastrointestinal disorders,3,N,N,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0004928,S00277,472,487,Aspartate aminotransferase increased,Investigations,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004929,S00277,722,735,Aspartate aminotransferase increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004930,S00277,190,217,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004931,S00277,42,61,Alanine aminotransferase increased,Investigations,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004932,S00277,327,341,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004933,S00277,673,702,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0004934,S00277,576,582,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004935,S00277,650,663,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004936,S00277,409,416,Complement activation,Immune system disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004937,S00278,531,552,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004938,S00278,165,175,Bilirubin increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004939,S00278,335,336,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004940,S00278,673,691,Complement activation,Immune system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004941,S00278,467,481,Mucosal inflammation,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0004942,S00278,503,531,Aphasia,Nervous system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004943,S00278,108,122,Tremor,Nervous system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004944,S00278,367,392,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004945,S00278,447,470,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0004946,S00279,6,12,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0004947,S00279,90,100,Alanine aminotransferase increased,Investigations,3,Y,Y,None,Recovering,N,0,N,0,N,N,N
AE0004948,S00279,367,385,Alanine aminotransferase increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004949,S00279,247,254,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0004950,S00279,256,283,Alanine aminotransferase increased,Investigations,3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004951,S00279,170,193,Anaemia,Blood and lymphatic system,4,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0004952,S00279,339,367,Tachycardia,Cardiac disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0004953,S00279,458,478,Hypogammaglobulinaemia,Immune system disorders,3,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004954,S00279,643,645,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004955,S00279,174,176,Hypotension,Vascular disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004956,S00279,719,733,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004957,S00279,408,430,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0004958,S00279,594,604,Fatigue,General disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0004959,S00279,278,293,Seizure,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004960,S00279,601,607,Aphasia,Nervous system disorders,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004961,S00279,420,431,Bilirubin increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004962,S00279,216,229,Diarrhoea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0004963,S00279,92,113,Diarrhoea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004964,S00279,224,250,Aphasia,Nervous system disorders,5,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0004965,S00279,429,437,Seizure,Nervous system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004966,S00279,67,80,Sepsis,Infections and infestations,3,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0004967,S00279,724,734,Tremor,Nervous system disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004968,S00279,250,276,Confusional state,Psychiatric disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004969,S00279,436,454,Seizure,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004970,S00279,229,251,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,None,Not recovered,N,0,N,0,N,Y,Y
AE0004971,S00280,1,9,Cytokine release syndrome,Immune system disorders,4,Y,Y,Tocilizumab,Recovered,Y,4,N,0,N,N,Y
AE0004972,S00280,43,52,Anaemia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004973,S00280,694,698,Cytomegalovirus infection,Infections and infestations,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0004974,S00280,470,499,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004975,S00280,414,415,Alanine aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0004976,S00280,279,301,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004977,S00280,77,104,Seizure,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004978,S00280,692,711,Anaemia,Blood and lymphatic system,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0004979,S00280,720,742,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0004980,S00280,261,273,Tachycardia,Cardiac disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004981,S00280,56,68,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,Hospitalization,Recovered,N,0,N,0,N,Y,Y
AE0004982,S00280,404,423,Confusional state,Psychiatric disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0004983,S00280,452,478,Complement activation,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004984,S00280,649,668,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004985,S00280,190,202,Vomiting,Gastrointestinal disorders,1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0004986,S00280,31,40,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004987,S00280,26,32,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004988,S00280,0,17,Seizure,Nervous system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0004989,S00280,134,146,Sepsis,Infections and infestations,4,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0004990,S00280,31,57,Cytomegalovirus infection,Infections and infestations,3,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0004991,S00280,159,181,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Dose modification,Recovering,N,0,N,0,N,Y,Y
AE0004992,S00280,384,408,Complement activation,Immune system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0004993,S00280,87,101,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,None,Recovering,N,0,N,0,N,Y,Y
AE0004994,S00280,182,207,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0004995,S00280,383,394,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004996,S00280,468,489,Hypotension,Vascular disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0004997,S00280,690,702,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004998,S00280,462,479,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0004999,S00280,428,455,Thrombocytopenia,Blood and lymphatic system,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0005000,S00281,528,533,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005001,S00281,329,343,Nausea,Gastrointestinal disorders,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005002,S00281,479,491,Aphasia,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005003,S00281,498,506,Complement activation,Immune system disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005004,S00281,88,105,Aphasia,Nervous system disorders,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005005,S00281,75,80,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005006,S00281,556,567,Aphasia,Nervous system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005007,S00281,154,165,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005008,S00281,116,123,Tremor,Nervous system disorders,2,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0005009,S00281,289,301,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0005010,S00281,150,174,Cytomegalovirus infection,Infections and infestations,4,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005011,S00281,443,455,Nausea,Gastrointestinal disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005012,S00281,62,85,Thrombocytopenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0005013,S00281,196,197,Tachycardia,Cardiac disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005014,S00282,702,722,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005015,S00282,409,428,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,Y,Y
AE0005016,S00282,235,246,Thrombocytopenia,Blood and lymphatic system,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005017,S00282,185,210,Pyrexia,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005018,S00282,84,86,Fatigue,General disorders,1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0005019,S00282,246,251,Confusional state,Psychiatric disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005020,S00282,404,424,Seizure,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005021,S00282,64,77,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005022,S00282,435,460,Neutropenia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005023,S00282,132,149,Complement activation,Immune system disorders,4,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005024,S00282,498,520,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005025,S00282,29,45,Fatigue,General disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005026,S00282,450,475,Aspartate aminotransferase increased,Investigations,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005027,S00282,589,611,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005028,S00283,366,386,Vomiting,Gastrointestinal disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0005029,S00283,445,472,Cough,"Respiratory, thoracic, mediastinal",3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005030,S00283,458,484,Cough,"Respiratory, thoracic, mediastinal",2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005031,S00283,275,289,Infusion related reaction,"Injury, poisoning, procedural",3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005032,S00283,140,157,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005033,S00283,505,519,Fatigue,General disorders,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005034,S00283,236,248,Aphasia,Nervous system disorders,3,Y,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005035,S00283,726,755,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005036,S00283,74,84,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Concomitant medication,Unknown,N,0,N,0,N,Y,Y
AE0005037,S00283,631,633,Headache,Nervous system disorders,2,N,Y,Dose modification,Unknown,N,0,N,0,N,N,N
AE0005038,S00283,676,696,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0005039,S00283,313,329,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005040,S00283,179,187,Thrombocytopenia,Blood and lymphatic system,4,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005041,S00283,514,540,Anaemia,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005042,S00283,63,92,Complement activation,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005043,S00283,215,233,Complement activation,Immune system disorders,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005044,S00283,105,117,Bilirubin increased,Investigations,2,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0005045,S00283,291,300,Anaemia,Blood and lymphatic system,2,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0005046,S00283,112,125,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005047,S00283,522,525,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005048,S00283,477,488,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005049,S00283,117,134,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0005050,S00283,222,233,Mucosal inflammation,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005051,S00284,367,389,Bilirubin increased,Investigations,1,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0005052,S00284,527,536,Neutropenia,Blood and lymphatic system,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0005053,S00284,685,700,Fatigue,General disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0005054,S00284,190,191,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0005055,S00284,185,194,Pyrexia,General disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005056,S00284,285,287,Seizure,Nervous system disorders,5,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0005057,S00284,469,486,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005058,S00284,596,617,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0005059,S00284,75,81,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005060,S00284,324,353,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005061,S00284,261,262,Aphasia,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005062,S00284,397,399,Diarrhoea,Gastrointestinal disorders,1,N,N,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0005063,S00284,579,582,Sepsis,Infections and infestations,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005064,S00284,343,366,Fatigue,General disorders,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005065,S00284,139,165,Hypotension,Vascular disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005066,S00284,576,597,Vomiting,Gastrointestinal disorders,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005067,S00284,513,536,Complement activation,Immune system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005068,S00284,78,100,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005069,S00284,416,434,Neutropenia,Blood and lymphatic system,3,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0005070,S00284,611,640,Complement activation,Immune system disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005071,S00284,364,391,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005072,S00284,664,668,Hypoxia,"Respiratory, thoracic, mediastinal",5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005073,S00284,664,668,Seizure,Nervous system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005074,S00284,92,103,Pyrexia,General disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005075,S00284,588,594,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005076,S00285,386,390,Complement activation,Immune system disorders,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005077,S00285,517,518,Fatigue,General disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0005078,S00285,711,739,Seizure,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005079,S00285,3,17,Cough,"Respiratory, thoracic, mediastinal",4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005080,S00285,290,306,Mucosal inflammation,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005081,S00285,370,374,Tremor,Nervous system disorders,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005082,S00285,533,553,Neutropenia,Blood and lymphatic system,5,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0005083,S00285,225,228,Sepsis,Infections and infestations,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005084,S00285,154,157,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005085,S00285,455,460,Anaemia,Blood and lymphatic system,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005086,S00285,638,643,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0005087,S00285,505,506,Tremor,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005088,S00285,2,18,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005089,S00285,518,541,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005090,S00285,111,131,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005091,S00285,652,660,Anaemia,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005092,S00285,480,500,Pyrexia,General disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005093,S00286,106,128,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005094,S00286,217,222,Tachycardia,Cardiac disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005095,S00286,276,285,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005096,S00286,692,713,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005097,S00286,564,584,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005098,S00286,78,80,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005099,S00286,173,194,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005100,S00286,348,359,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005101,S00286,480,493,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005102,S00286,453,464,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005103,S00286,526,553,Sepsis,Infections and infestations,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005104,S00286,572,576,Nausea,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005105,S00286,682,689,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0005106,S00286,288,298,Neutropenia,Blood and lymphatic system,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0005107,S00286,287,291,Thrombocytopenia,Blood and lymphatic system,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005108,S00286,89,118,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005109,S00286,70,90,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005110,S00286,128,142,Cytomegalovirus infection,Infections and infestations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005111,S00286,214,232,Complement activation,Immune system disorders,1,N,Y,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0005112,S00286,326,340,Neutropenia,Blood and lymphatic system,5,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0005113,S00286,66,80,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0005114,S00286,411,419,Alanine aminotransferase increased,Investigations,5,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0005115,S00288,216,229,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005116,S00288,66,73,Tachycardia,Cardiac disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005117,S00288,220,226,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0005118,S00288,577,597,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005119,S00288,473,499,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005120,S00288,540,563,Complement activation,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005121,S00288,205,214,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005122,S00288,658,677,Fatigue,General disorders,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0005123,S00288,168,195,Hypogammaglobulinaemia,Immune system disorders,4,N,Y,Dose modification,Unknown,N,0,N,0,N,N,N
AE0005124,S00288,68,96,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005125,S00288,153,167,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005126,S00288,424,427,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005127,S00288,707,730,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005128,S00288,697,716,Fatigue,General disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005129,S00288,226,231,Hypogammaglobulinaemia,Immune system disorders,2,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0005130,S00288,277,289,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005131,S00288,519,531,Hypotension,Vascular disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005132,S00288,689,705,Bilirubin increased,Investigations,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005133,S00288,664,682,Seizure,Nervous system disorders,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005134,S00288,412,438,Seizure,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005135,S00288,394,412,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Dose modification,Recovered,N,0,N,0,N,Y,Y
AE0005136,S00288,459,470,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005137,S00288,727,733,Sepsis,Infections and infestations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005138,S00288,110,137,Headache,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005139,S00288,45,51,Anaemia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005140,S00288,258,266,Neutropenia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005141,S00288,10,17,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005142,S00289,537,562,Headache,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005143,S00289,35,53,Cough,"Respiratory, thoracic, mediastinal",3,Y,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0005144,S00289,616,639,Complement activation,Immune system disorders,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0005145,S00289,637,656,Thrombocytopenia,Blood and lymphatic system,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005146,S00289,241,263,Aphasia,Nervous system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005147,S00289,290,313,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005148,S00289,557,584,Hypotension,Vascular disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0005149,S00289,524,546,Bilirubin increased,Investigations,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005150,S00291,3,17,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0005151,S00291,9,28,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0005152,S00291,594,598,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0005153,S00291,145,171,Seizure,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005154,S00291,149,178,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005155,S00291,646,660,Vomiting,Gastrointestinal disorders,3,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0005156,S00291,633,646,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Recovering,N,0,N,0,N,Y,Y
AE0005157,S00291,678,697,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005158,S00291,26,28,Tremor,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005159,S00291,630,635,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0005160,S00291,637,639,Aspartate aminotransferase increased,Investigations,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0005161,S00291,680,708,Aspartate aminotransferase increased,Investigations,1,N,N,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0005162,S00291,507,533,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005163,S00291,230,248,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005164,S00291,273,279,Aspartate aminotransferase increased,Investigations,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005165,S00291,202,227,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005166,S00291,562,566,Cytomegalovirus infection,Infections and infestations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005167,S00291,219,243,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005168,S00291,631,647,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005169,S00291,604,610,Aphasia,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005170,S00291,376,382,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005171,S00291,665,689,Headache,Nervous system disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005172,S00291,150,152,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005173,S00291,439,465,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005174,S00291,41,67,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005175,S00291,630,633,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005176,S00291,129,148,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005177,S00291,457,469,Complement activation,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005178,S00291,585,604,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005179,S00291,448,472,Fatigue,General disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0005180,S00291,704,709,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005181,S00291,293,305,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005182,S00291,672,673,Tachycardia,Cardiac disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005183,S00291,469,471,Sepsis,Infections and infestations,5,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0005184,S00291,26,45,Seizure,Nervous system disorders,4,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0005185,S00291,539,553,Cytomegalovirus infection,Infections and infestations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005186,S00291,277,283,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005187,S00291,159,172,Headache,Nervous system disorders,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0005188,S00292,533,555,Tremor,Nervous system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005189,S00292,514,543,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005190,S00292,444,451,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0005191,S00292,520,536,Nausea,Gastrointestinal disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005192,S00292,443,453,Complement activation,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005193,S00292,408,427,Hypotension,Vascular disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005194,S00292,217,226,Tremor,Nervous system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005195,S00292,570,599,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005196,S00292,344,355,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005197,S00292,437,438,Cytomegalovirus infection,Infections and infestations,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005198,S00292,3,25,Thrombocytopenia,Blood and lymphatic system,5,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005199,S00293,4,13,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0005200,S00293,238,242,Hypotension,Vascular disorders,3,Y,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005201,S00293,607,618,Seizure,Nervous system disorders,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005202,S00293,411,435,Confusional state,Psychiatric disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005203,S00293,565,579,Hypogammaglobulinaemia,Immune system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005204,S00293,623,652,Tremor,Nervous system disorders,1,N,N,Drug interrupted,Fatal,N,0,N,0,N,N,N
AE0005205,S00293,37,62,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005206,S00293,574,578,Fatigue,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005207,S00293,221,225,Hypotension,Vascular disorders,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005208,S00293,574,579,Vomiting,Gastrointestinal disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005209,S00293,574,588,Anaemia,Blood and lymphatic system,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0005210,S00293,487,506,Alanine aminotransferase increased,Investigations,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0005211,S00293,20,47,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005212,S00293,82,83,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,Y,Y
AE0005213,S00293,49,57,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0005214,S00293,382,406,Diarrhoea,Gastrointestinal disorders,4,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005215,S00293,452,460,Neutropenia,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005216,S00293,88,90,Aspartate aminotransferase increased,Investigations,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005217,S00293,316,324,Fatigue,General disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005218,S00293,652,670,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0005219,S00293,158,184,Aphasia,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005220,S00293,56,57,Fatigue,General disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0005221,S00293,149,173,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005222,S00293,222,230,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005223,S00293,505,507,Complement activation,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005224,S00293,297,320,Sepsis,Infections and infestations,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0005225,S00293,38,61,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005226,S00295,2,9,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0005227,S00295,540,553,Tachycardia,Cardiac disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005228,S00295,293,303,Aphasia,Nervous system disorders,3,Y,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0005229,S00295,664,674,Complement activation,Immune system disorders,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0005230,S00295,495,515,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005231,S00295,90,95,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005232,S00295,637,649,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005233,S00295,164,171,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005234,S00295,25,40,Anaemia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005235,S00295,306,317,Aphasia,Nervous system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005236,S00295,636,658,Aphasia,Nervous system disorders,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005237,S00295,362,365,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005238,S00295,6,19,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005239,S00295,568,597,Fatigue,General disorders,1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0005240,S00295,487,491,Sepsis,Infections and infestations,3,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0005241,S00295,443,460,Headache,Nervous system disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005242,S00295,65,69,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0005243,S00295,421,444,Fatigue,General disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005244,S00295,498,510,Confusional state,Psychiatric disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005245,S00295,106,109,Tremor,Nervous system disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005246,S00295,494,518,Anaemia,Blood and lymphatic system,4,N,N,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0005247,S00295,395,403,Sepsis,Infections and infestations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005248,S00295,478,480,Headache,Nervous system disorders,5,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005249,S00295,433,456,Tachycardia,Cardiac disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005250,S00295,211,235,Fatigue,General disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0005251,S00295,137,157,Pyrexia,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005252,S00295,1,15,Cytomegalovirus infection,Infections and infestations,2,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0005253,S00295,174,189,Headache,Nervous system disorders,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0005254,S00295,328,352,Fatigue,General disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005255,S00295,159,187,Hypogammaglobulinaemia,Immune system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005256,S00295,149,164,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0005257,S00296,4,23,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0005258,S00296,181,208,Vomiting,Gastrointestinal disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005259,S00296,463,472,Anaemia,Blood and lymphatic system,2,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0005260,S00296,500,508,Alanine aminotransferase increased,Investigations,5,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005261,S00296,134,151,Anaemia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005262,S00296,56,61,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005263,S00296,623,651,Confusional state,Psychiatric disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005264,S00296,82,104,Hypogammaglobulinaemia,Immune system disorders,2,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0005265,S00296,343,356,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005266,S00296,30,41,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0005267,S00296,564,572,Neutropenia,Blood and lymphatic system,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0005268,S00296,390,405,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005269,S00296,274,281,Bilirubin increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005270,S00296,12,35,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,None,Unknown,N,0,N,0,N,Y,Y
AE0005271,S00296,49,76,Mucosal inflammation,Gastrointestinal disorders,2,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0005272,S00296,229,235,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005273,S00296,6,20,Tachycardia,Cardiac disorders,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005274,S00296,150,176,Cytomegalovirus infection,Infections and infestations,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005275,S00296,235,253,Thrombotic microangiopathy,Blood and lymphatic system,5,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0005276,S00296,706,717,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0005277,S00296,671,678,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005278,S00296,670,681,Anaemia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005279,S00296,290,304,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005280,S00296,83,103,Anaemia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005281,S00296,455,456,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0005282,S00296,400,423,Seizure,Nervous system disorders,4,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0005283,S00297,569,570,Tremor,Nervous system disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005284,S00297,208,213,Sepsis,Infections and infestations,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005285,S00297,243,262,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0005286,S00297,563,565,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005287,S00297,113,138,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005288,S00297,554,555,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005289,S00297,531,555,Seizure,Nervous system disorders,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0005290,S00297,666,683,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005291,S00297,580,601,Hypotension,Vascular disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005292,S00297,131,149,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0005293,S00297,131,139,Diarrhoea,Gastrointestinal disorders,2,N,N,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0005294,S00297,604,630,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005295,S00297,591,616,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005296,S00297,213,229,Confusional state,Psychiatric disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005297,S00297,531,534,Anaemia,Blood and lymphatic system,1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0005298,S00297,473,498,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005299,S00298,5,20,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0005300,S00298,18,25,Thrombotic microangiopathy,Blood and lymphatic system,3,Y,Y,Drug interrupted,Recovering,N,0,N,0,N,Y,Y
AE0005301,S00298,354,360,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005302,S00298,347,372,Mucosal inflammation,Gastrointestinal disorders,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005303,S00298,402,407,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005304,S00298,527,536,Cytomegalovirus infection,Infections and infestations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005305,S00298,602,629,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005306,S00298,646,669,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005307,S00298,654,660,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005308,S00298,524,539,Complement activation,Immune system disorders,1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0005309,S00298,379,391,Vomiting,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0005310,S00298,190,209,Cytomegalovirus infection,Infections and infestations,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005311,S00298,483,489,Sepsis,Infections and infestations,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005312,S00298,80,85,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005313,S00298,51,74,Neutropenia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005314,S00298,143,151,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005315,S00298,60,66,Headache,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005316,S00298,658,679,Headache,Nervous system disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005317,S00298,573,593,Vomiting,Gastrointestinal disorders,2,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0005318,S00298,445,453,Thrombocytopenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005319,S00298,672,680,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005320,S00298,144,154,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005321,S00298,427,432,Nausea,Gastrointestinal disorders,1,N,N,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0005322,S00298,458,460,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005323,S00298,237,243,Nausea,Gastrointestinal disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0005324,S00298,18,32,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005325,S00298,133,149,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005326,S00298,88,108,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005327,S00298,591,617,Diarrhoea,Gastrointestinal disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0005328,S00298,373,389,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005329,S00298,717,734,Pyrexia,General disorders,2,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0005330,S00298,74,103,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005331,S00298,295,299,Cough,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005332,S00298,697,713,Nausea,Gastrointestinal disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005333,S00298,222,247,Neutropenia,Blood and lymphatic system,2,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0005334,S00298,555,584,Aphasia,Nervous system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005335,S00298,568,578,Anaemia,Blood and lymphatic system,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005336,S00298,11,33,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005337,S00298,253,279,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0005338,S00298,183,203,Aphasia,Nervous system disorders,4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005339,S00298,228,257,Aphasia,Nervous system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005340,S00298,133,145,Diarrhoea,Gastrointestinal disorders,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005341,S00299,2,16,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0005342,S00299,484,504,Pyrexia,General disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005343,S00299,688,701,Bilirubin increased,Investigations,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005344,S00299,294,321,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005345,S00299,603,608,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005346,S00299,168,187,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005347,S00299,364,372,Confusional state,Psychiatric disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005348,S00299,50,70,Cytomegalovirus infection,Infections and infestations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005349,S00299,199,208,Bilirubin increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005350,S00299,39,50,Hypogammaglobulinaemia,Immune system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005351,S00299,311,323,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005352,S00299,538,550,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005353,S00299,68,76,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005354,S00299,260,267,Seizure,Nervous system disorders,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0005355,S00299,109,113,Alanine aminotransferase increased,Investigations,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005356,S00299,219,248,Fatigue,General disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005357,S00299,478,483,Complement activation,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005358,S00299,367,368,Seizure,Nervous system disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005359,S00299,435,436,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005360,S00299,702,706,Vomiting,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005361,S00299,439,442,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005362,S00299,725,745,Tremor,Nervous system disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005363,S00299,283,286,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005364,S00299,188,206,Fatigue,General disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005365,S00299,696,699,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005366,S00299,717,737,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005367,S00299,555,560,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005368,S00299,726,755,Diarrhoea,Gastrointestinal disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005369,S00299,680,688,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0005370,S00299,414,415,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0005371,S00299,659,673,Complement activation,Immune system disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005372,S00299,336,365,Neutropenia,Blood and lymphatic system,5,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005373,S00299,196,198,Alanine aminotransferase increased,Investigations,2,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0005374,S00299,610,617,Thrombocytopenia,Blood and lymphatic system,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005375,S00299,604,633,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005376,S00300,7,24,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0005377,S00300,712,727,Tremor,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005378,S00300,500,512,Mucosal inflammation,Gastrointestinal disorders,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005379,S00300,108,126,Aphasia,Nervous system disorders,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0005380,S00300,2,23,Vomiting,Gastrointestinal disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005381,S00300,228,245,Complement activation,Immune system disorders,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005382,S00300,466,495,Headache,Nervous system disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005383,S00300,242,253,Neutropenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0005384,S00300,533,534,Vomiting,Gastrointestinal disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0005385,S00300,249,258,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,Y,Y
AE0005386,S00300,571,575,Cytomegalovirus infection,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005387,S00300,252,261,Tremor,Nervous system disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005388,S00300,333,346,Aspartate aminotransferase increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005389,S00300,660,673,Bilirubin increased,Investigations,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0005390,S00300,338,360,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Unknown,N,0,N,0,N,Y,Y
AE0005391,S00300,460,482,Bilirubin increased,Investigations,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005392,S00300,534,554,Sepsis,Infections and infestations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005393,S00300,473,494,Aspartate aminotransferase increased,Investigations,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005394,S00300,458,470,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005395,S00300,173,185,Fatigue,General disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005396,S00300,513,539,Neutropenia,Blood and lymphatic system,5,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005397,S00300,687,707,Seizure,Nervous system disorders,1,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0005398,S00300,212,227,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005399,S00300,8,29,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005400,S00300,615,644,Cytomegalovirus infection,Infections and infestations,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005401,S00300,449,467,Confusional state,Psychiatric disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005402,S00300,351,380,Complement activation,Immune system disorders,2,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0005403,S00301,191,196,Fatigue,General disorders,3,Y,Y,None,Recovering,N,0,N,0,N,N,N
AE0005404,S00301,277,278,Cytomegalovirus infection,Infections and infestations,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005405,S00301,134,142,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005406,S00301,570,580,Sepsis,Infections and infestations,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005407,S00301,348,377,Infusion related reaction,"Injury, poisoning, procedural",4,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005408,S00301,546,573,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005409,S00301,724,739,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005410,S00301,196,204,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005411,S00301,83,101,Diarrhoea,Gastrointestinal disorders,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005412,S00301,635,652,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005413,S00301,247,249,Nausea,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005414,S00301,543,545,Thrombocytopenia,Blood and lymphatic system,5,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005415,S00301,372,382,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005416,S00301,432,451,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005417,S00301,124,141,Thrombocytopenia,Blood and lymphatic system,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005418,S00301,401,414,Cough,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005419,S00301,45,49,Thrombocytopenia,Blood and lymphatic system,2,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0005420,S00301,572,600,Hypotension,Vascular disorders,3,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0005421,S00301,634,639,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005422,S00301,380,383,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005423,S00301,561,582,Sepsis,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005424,S00301,135,164,Thrombotic microangiopathy,Blood and lymphatic system,5,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0005425,S00301,552,567,Fatigue,General disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005426,S00301,604,622,Nausea,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005427,S00301,591,597,Mucosal inflammation,Gastrointestinal disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005428,S00301,307,332,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005429,S00301,302,322,Pyrexia,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005430,S00301,515,537,Thrombocytopenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005431,S00301,325,340,Headache,Nervous system disorders,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005432,S00305,2,14,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0005433,S00305,693,717,Sepsis,Infections and infestations,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005434,S00305,377,389,Tachycardia,Cardiac disorders,2,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0005435,S00305,518,545,Bilirubin increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005436,S00305,535,550,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005437,S00305,590,601,Sepsis,Infections and infestations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005438,S00305,358,377,Tremor,Nervous system disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0005439,S00305,641,645,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005440,S00305,58,80,Aphasia,Nervous system disorders,3,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0005441,S00305,505,528,Bilirubin increased,Investigations,5,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005442,S00305,695,702,Hypotension,Vascular disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005443,S00305,4,11,Vomiting,Gastrointestinal disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005444,S00305,301,302,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005445,S00305,209,221,Alanine aminotransferase increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005446,S00305,95,114,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005447,S00305,342,348,Hypotension,Vascular disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005448,S00305,606,618,Seizure,Nervous system disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005449,S00305,114,142,Bilirubin increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005450,S00305,221,241,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005451,S00305,106,117,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005452,S00305,693,717,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005453,S00305,285,309,Fatigue,General disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005454,S00305,47,63,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005455,S00305,24,40,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005456,S00305,551,564,Pyrexia,General disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005457,S00305,474,503,Alanine aminotransferase increased,Investigations,5,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005458,S00305,178,193,Anaemia,Blood and lymphatic system,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005459,S00305,257,262,Complement activation,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005460,S00305,485,487,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005461,S00305,235,263,Sepsis,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005462,S00305,110,129,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005463,S00305,624,635,Hypotension,Vascular disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005464,S00305,520,521,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005465,S00305,262,265,Aphasia,Nervous system disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0005466,S00305,449,450,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,Y,Y
AE0005467,S00305,592,603,Headache,Nervous system disorders,3,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0005468,S00305,707,735,Hypotension,Vascular disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005469,S00305,164,193,Nausea,Gastrointestinal disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0005470,S00307,576,592,Sepsis,Infections and infestations,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005471,S00307,345,356,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,Hospitalization,Recovered,N,0,N,0,N,Y,Y
AE0005472,S00307,352,373,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005473,S00307,436,465,Complement activation,Immune system disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005474,S00307,232,251,Pyrexia,General disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005475,S00307,49,67,Sepsis,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005476,S00307,624,631,Thrombocytopenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005477,S00307,658,683,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005478,S00307,606,626,Bilirubin increased,Investigations,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0005479,S00307,201,218,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005480,S00307,145,165,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005481,S00307,500,521,Hypotension,Vascular disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005482,S00307,144,161,Seizure,Nervous system disorders,4,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005483,S00307,567,586,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005484,S00307,397,408,Aphasia,Nervous system disorders,5,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005485,S00307,723,727,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005486,S00307,589,591,Aphasia,Nervous system disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0005487,S00307,213,219,Aspartate aminotransferase increased,Investigations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005488,S00307,377,406,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005489,S00307,349,354,Tachycardia,Cardiac disorders,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0005490,S00307,51,55,Tremor,Nervous system disorders,4,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005491,S00307,657,675,Anaemia,Blood and lymphatic system,3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005492,S00308,185,204,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005493,S00308,412,427,Tremor,Nervous system disorders,3,Y,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005494,S00308,673,685,Tremor,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005495,S00308,267,270,Nausea,Gastrointestinal disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005496,S00308,706,712,Tremor,Nervous system disorders,3,Y,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0005497,S00308,585,599,Confusional state,Psychiatric disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005498,S00308,374,388,Tremor,Nervous system disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005499,S00308,37,59,Seizure,Nervous system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005500,S00308,480,501,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005501,S00308,315,323,Tremor,Nervous system disorders,5,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0005502,S00308,542,545,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005503,S00308,176,197,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005504,S00308,555,559,Seizure,Nervous system disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005505,S00308,152,173,Hypogammaglobulinaemia,Immune system disorders,3,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0005506,S00308,639,660,Cytomegalovirus infection,Infections and infestations,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005507,S00308,19,33,Aphasia,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005508,S00308,294,317,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005509,S00308,257,286,Confusional state,Psychiatric disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005510,S00308,284,289,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005511,S00308,708,710,Nausea,Gastrointestinal disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005512,S00308,600,602,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005513,S00308,565,581,Thrombocytopenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005514,S00308,724,733,Aphasia,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005515,S00308,482,488,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0005516,S00309,263,275,Diarrhoea,Gastrointestinal disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005517,S00309,701,708,Complement activation,Immune system disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005518,S00309,625,635,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005519,S00309,567,572,Alanine aminotransferase increased,Investigations,3,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005520,S00309,483,484,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005521,S00309,281,294,Cytomegalovirus infection,Infections and infestations,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005522,S00309,123,134,Hypotension,Vascular disorders,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0005523,S00309,451,452,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005524,S00309,201,210,Hypotension,Vascular disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005525,S00309,48,54,Aspartate aminotransferase increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005526,S00309,152,165,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005527,S00309,633,646,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0005528,S00309,463,477,Seizure,Nervous system disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005529,S00309,340,349,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005530,S00309,640,652,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005531,S00309,142,158,Seizure,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005532,S00309,701,717,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005533,S00312,350,359,Diarrhoea,Gastrointestinal disorders,3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005534,S00312,608,620,Nausea,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0005535,S00312,643,658,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005536,S00312,189,213,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005537,S00312,413,433,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005538,S00312,176,198,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005539,S00312,597,625,Hypotension,Vascular disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005540,S00312,617,635,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0005541,S00312,569,584,Hypogammaglobulinaemia,Immune system disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005542,S00312,424,435,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0005543,S00312,219,248,Aphasia,Nervous system disorders,5,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005544,S00312,357,385,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005545,S00313,53,67,Pyrexia,General disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0005546,S00313,364,389,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005547,S00313,717,727,Bilirubin increased,Investigations,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005548,S00313,277,297,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005549,S00313,116,119,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0005550,S00313,608,627,Anaemia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005551,S00313,524,531,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005552,S00313,304,329,Pyrexia,General disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005553,S00313,323,336,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005554,S00313,692,693,Anaemia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005555,S00313,40,55,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005556,S00313,687,712,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005557,S00313,170,188,Headache,Nervous system disorders,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005558,S00313,297,299,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,Y,Y
AE0005559,S00313,34,58,Thrombotic microangiopathy,Blood and lymphatic system,5,N,N,None,Recovering,N,0,N,0,N,Y,Y
AE0005560,S00313,707,716,Aspartate aminotransferase increased,Investigations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005561,S00313,620,627,Thrombotic microangiopathy,Blood and lymphatic system,5,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0005562,S00313,552,567,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005563,S00313,116,130,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005564,S00313,606,631,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005565,S00313,223,243,Confusional state,Psychiatric disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005566,S00313,412,416,Hypotension,Vascular disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005567,S00313,401,409,Sepsis,Infections and infestations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005568,S00313,294,321,Anaemia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005569,S00314,173,182,Thrombotic microangiopathy,Blood and lymphatic system,5,Y,N,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0005570,S00314,368,390,Aphasia,Nervous system disorders,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005571,S00314,278,292,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005572,S00314,160,162,Pyrexia,General disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005573,S00314,344,369,Bilirubin increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005574,S00314,315,317,Confusional state,Psychiatric disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005575,S00314,254,258,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovering,N,0,N,0,N,Y,Y
AE0005576,S00314,633,656,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005577,S00314,508,525,Headache,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005578,S00314,37,41,Fatigue,General disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005579,S00314,319,333,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005580,S00314,178,196,Alanine aminotransferase increased,Investigations,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005581,S00314,426,443,Sepsis,Infections and infestations,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005582,S00314,336,344,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005583,S00314,588,599,Tachycardia,Cardiac disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0005584,S00314,550,565,Seizure,Nervous system disorders,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005585,S00314,714,738,Vomiting,Gastrointestinal disorders,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0005586,S00314,138,142,Diarrhoea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005587,S00314,18,29,Sepsis,Infections and infestations,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005588,S00314,641,647,Vomiting,Gastrointestinal disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005589,S00315,449,462,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005590,S00315,326,336,Headache,Nervous system disorders,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005591,S00315,526,550,Neutropenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005592,S00315,447,463,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005593,S00315,485,497,Seizure,Nervous system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005594,S00315,330,345,Headache,Nervous system disorders,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005595,S00315,683,712,Seizure,Nervous system disorders,2,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0005596,S00315,489,510,Diarrhoea,Gastrointestinal disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005597,S00315,243,267,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005598,S00315,565,581,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005599,S00315,346,366,Sepsis,Infections and infestations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005600,S00315,718,737,Hypotension,Vascular disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005601,S00315,24,33,Fatigue,General disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005602,S00315,637,648,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005603,S00315,154,178,Neutropenia,Blood and lymphatic system,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005604,S00315,722,723,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005605,S00315,537,555,Confusional state,Psychiatric disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005606,S00315,396,398,Aspartate aminotransferase increased,Investigations,1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0005607,S00316,454,483,Complement activation,Immune system disorders,2,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0005608,S00316,589,596,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,Y,Y
AE0005609,S00316,477,505,Sepsis,Infections and infestations,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005610,S00316,58,60,Alanine aminotransferase increased,Investigations,3,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0005611,S00316,605,619,Aspartate aminotransferase increased,Investigations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005612,S00316,450,455,Thrombocytopenia,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005613,S00316,715,741,Anaemia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005614,S00316,626,655,Aspartate aminotransferase increased,Investigations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005615,S00316,285,293,Tachycardia,Cardiac disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005616,S00316,257,275,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005617,S00316,142,154,Tachycardia,Cardiac disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005618,S00316,286,298,Seizure,Nervous system disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005619,S00316,210,217,Fatigue,General disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005620,S00316,17,38,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005621,S00316,708,718,Alanine aminotransferase increased,Investigations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005622,S00316,599,604,Tremor,Nervous system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005623,S00316,307,322,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005624,S00316,359,382,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005625,S00316,372,390,Complement activation,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005626,S00317,240,258,Hypotension,Vascular disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005627,S00317,683,712,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovering,N,0,N,0,N,Y,Y
AE0005628,S00317,303,311,Thrombocytopenia,Blood and lymphatic system,3,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0005629,S00317,227,249,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005630,S00317,651,666,Hypotension,Vascular disorders,3,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0005631,S00317,57,65,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0005632,S00317,53,82,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005633,S00317,482,495,Complement activation,Immune system disorders,3,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0005634,S00317,41,70,Tremor,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005635,S00317,283,305,Aphasia,Nervous system disorders,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005636,S00317,304,311,Seizure,Nervous system disorders,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005637,S00317,363,371,Infusion related reaction,"Injury, poisoning, procedural",4,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005638,S00317,285,310,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005639,S00317,154,171,Aspartate aminotransferase increased,Investigations,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0005640,S00317,53,74,Bilirubin increased,Investigations,2,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0005641,S00317,449,454,Hypotension,Vascular disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005642,S00317,367,369,Pyrexia,General disorders,5,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005643,S00317,520,526,Sepsis,Infections and infestations,4,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0005644,S00317,251,276,Fatigue,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005645,S00317,241,256,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005646,S00317,365,368,Complement activation,Immune system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005647,S00317,416,441,Aspartate aminotransferase increased,Investigations,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005648,S00317,58,73,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005649,S00317,284,293,Aphasia,Nervous system disorders,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0005650,S00317,340,343,Diarrhoea,Gastrointestinal disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005651,S00317,133,139,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005652,S00317,12,22,Neutropenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005653,S00317,536,565,Thrombocytopenia,Blood and lymphatic system,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005654,S00318,6,26,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0005655,S00318,5,9,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,2,N,Y,Corticosteroids,Recovered,N,0,Y,2,N,N,Y
AE0005656,S00318,50,70,Vomiting,Gastrointestinal disorders,3,Y,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005657,S00318,112,138,Tachycardia,Cardiac disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005658,S00318,583,588,Headache,Nervous system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005659,S00318,325,349,Bilirubin increased,Investigations,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005660,S00318,525,548,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0005661,S00318,442,462,Nausea,Gastrointestinal disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005662,S00318,547,551,Neutropenia,Blood and lymphatic system,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005663,S00318,496,514,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0005664,S00318,686,706,Complement activation,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005665,S00318,437,443,Nausea,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005666,S00318,109,136,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005667,S00318,111,136,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005668,S00318,461,489,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005669,S00318,322,340,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0005670,S00318,102,110,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0005671,S00318,54,81,Aphasia,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005672,S00318,183,188,Hypotension,Vascular disorders,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0005673,S00318,574,591,Tremor,Nervous system disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005674,S00318,136,154,Hypotension,Vascular disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0005675,S00318,626,650,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005676,S00318,75,101,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005677,S00318,24,47,Aphasia,Nervous system disorders,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005678,S00318,713,725,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005679,S00318,552,566,Hypogammaglobulinaemia,Immune system disorders,4,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005680,S00318,126,149,Aspartate aminotransferase increased,Investigations,2,N,Y,Drug interrupted,Fatal,N,0,N,0,N,N,N
AE0005681,S00318,470,481,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005682,S00318,495,523,Sepsis,Infections and infestations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005683,S00318,684,694,Tremor,Nervous system disorders,1,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0005684,S00318,246,254,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005685,S00318,716,724,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0005686,S00318,507,518,Aphasia,Nervous system disorders,5,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005687,S00318,460,484,Mucosal inflammation,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005688,S00318,433,441,Complement activation,Immune system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005689,S00318,468,482,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005690,S00318,498,504,Hypogammaglobulinaemia,Immune system disorders,5,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0005691,S00319,395,398,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005692,S00319,278,296,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005693,S00319,342,351,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005694,S00319,381,390,Complement activation,Immune system disorders,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0005695,S00319,362,390,Diarrhoea,Gastrointestinal disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005696,S00319,464,476,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005697,S00319,647,669,Anaemia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005698,S00319,401,426,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005699,S00319,216,243,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0005700,S00319,63,77,Complement activation,Immune system disorders,1,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0005701,S00319,454,455,Diarrhoea,Gastrointestinal disorders,1,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0005702,S00319,318,325,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005703,S00319,116,128,Fatigue,General disorders,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0005704,S00319,719,725,Nausea,Gastrointestinal disorders,5,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005705,S00319,523,527,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005706,S00319,287,292,Bilirubin increased,Investigations,3,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0005707,S00319,589,593,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005708,S00319,574,588,Sepsis,Infections and infestations,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005709,S00319,276,287,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005710,S00319,292,306,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005711,S00319,557,566,Bilirubin increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005712,S00319,121,124,Neutropenia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0005713,S00319,138,166,Thrombocytopenia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005714,S00320,437,451,Neutropenia,Blood and lymphatic system,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0005715,S00320,77,85,Sepsis,Infections and infestations,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005716,S00320,535,540,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005717,S00320,677,699,Bilirubin increased,Investigations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005718,S00320,563,586,Anaemia,Blood and lymphatic system,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005719,S00320,86,101,Complement activation,Immune system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005720,S00320,657,663,Cough,"Respiratory, thoracic, mediastinal",3,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0005721,S00320,703,709,Hypotension,Vascular disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005722,S00320,232,251,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005723,S00320,484,488,Aphasia,Nervous system disorders,4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005724,S00320,85,99,Bilirubin increased,Investigations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005725,S00320,261,284,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005726,S00320,103,126,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0005727,S00320,484,506,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0005728,S00320,657,664,Headache,Nervous system disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0005729,S00320,618,633,Sepsis,Infections and infestations,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005730,S00320,124,126,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,Concomitant medication,Recovering,N,0,N,0,N,Y,Y
AE0005731,S00320,39,62,Alanine aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0005732,S00320,605,611,Confusional state,Psychiatric disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005733,S00321,1,12,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0005734,S00321,8,11,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0005735,S00321,188,207,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005736,S00321,491,492,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005737,S00321,13,36,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005738,S00321,82,102,Bilirubin increased,Investigations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005739,S00321,490,503,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005740,S00321,587,588,Hypotension,Vascular disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005741,S00321,109,112,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005742,S00321,520,536,Neutropenia,Blood and lymphatic system,1,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0005743,S00321,363,378,Nausea,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005744,S00321,619,625,Headache,Nervous system disorders,3,N,N,None,Unknown,N,0,N,0,N,N,N
AE0005745,S00321,181,186,Tremor,Nervous system disorders,3,N,Y,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0005746,S00321,207,216,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005747,S00321,600,620,Confusional state,Psychiatric disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005748,S00321,47,71,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005749,S00321,35,51,Sepsis,Infections and infestations,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005750,S00321,617,619,Hypotension,Vascular disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005751,S00321,369,384,Sepsis,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005752,S00321,712,732,Aphasia,Nervous system disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005753,S00321,142,156,Aspartate aminotransferase increased,Investigations,1,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0005754,S00321,140,142,Cytomegalovirus infection,Infections and infestations,3,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0005755,S00321,350,376,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,Hospitalization,Recovering,N,0,N,0,N,Y,Y
AE0005756,S00321,586,613,Aspartate aminotransferase increased,Investigations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005757,S00321,165,186,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005758,S00321,668,672,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005759,S00323,543,553,Neutropenia,Blood and lymphatic system,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0005760,S00323,377,383,Vomiting,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005761,S00323,693,708,Mucosal inflammation,Gastrointestinal disorders,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0005762,S00323,689,707,Vomiting,Gastrointestinal disorders,3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005763,S00323,149,156,Headache,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005764,S00323,587,595,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005765,S00323,339,345,Seizure,Nervous system disorders,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005766,S00323,394,410,Fatigue,General disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005767,S00323,678,689,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005768,S00323,329,335,Sepsis,Infections and infestations,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005769,S00323,386,401,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005770,S00323,327,333,Aphasia,Nervous system disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005771,S00323,258,268,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005772,S00323,390,404,Nausea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005773,S00323,405,406,Alanine aminotransferase increased,Investigations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005774,S00323,549,565,Seizure,Nervous system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005775,S00323,84,112,Bilirubin increased,Investigations,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0005776,S00323,470,494,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005777,S00323,347,356,Seizure,Nervous system disorders,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005778,S00323,556,557,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005779,S00323,570,583,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005780,S00324,348,377,Cough,"Respiratory, thoracic, mediastinal",3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0005781,S00324,198,200,Vomiting,Gastrointestinal disorders,3,Y,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005782,S00324,486,511,Sepsis,Infections and infestations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005783,S00324,355,374,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005784,S00324,718,721,Aspartate aminotransferase increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005785,S00324,149,163,Hypotension,Vascular disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005786,S00324,434,453,Hypotension,Vascular disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005787,S00324,77,105,Anaemia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005788,S00324,583,589,Pyrexia,General disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005789,S00324,178,198,Sepsis,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005790,S00324,138,162,Vomiting,Gastrointestinal disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005791,S00325,6,18,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0005792,S00325,292,306,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005793,S00325,141,150,Vomiting,Gastrointestinal disorders,3,Y,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005794,S00325,138,140,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005795,S00325,666,675,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005796,S00325,235,239,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005797,S00325,63,84,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005798,S00325,112,134,Tremor,Nervous system disorders,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005799,S00325,338,366,Sepsis,Infections and infestations,5,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005800,S00325,378,396,Fatigue,General disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005801,S00325,712,715,Seizure,Nervous system disorders,5,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005802,S00325,276,285,Diarrhoea,Gastrointestinal disorders,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005803,S00325,284,300,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005804,S00325,233,253,Cough,"Respiratory, thoracic, mediastinal",3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005805,S00325,455,477,Nausea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005806,S00325,528,552,Vomiting,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0005807,S00325,257,284,Cough,"Respiratory, thoracic, mediastinal",4,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005808,S00325,696,703,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005809,S00325,712,727,Seizure,Nervous system disorders,2,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0005810,S00325,260,280,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005811,S00325,77,84,Bilirubin increased,Investigations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005812,S00325,511,514,Confusional state,Psychiatric disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005813,S00325,380,401,Cytomegalovirus infection,Infections and infestations,4,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0005814,S00325,209,223,Hypotension,Vascular disorders,3,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0005815,S00325,132,139,Hypotension,Vascular disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0005816,S00325,389,405,Seizure,Nervous system disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005817,S00325,217,229,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0005818,S00325,214,226,Fatigue,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005819,S00326,250,274,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005820,S00326,663,673,Cytomegalovirus infection,Infections and infestations,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005821,S00326,24,26,Complement activation,Immune system disorders,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005822,S00326,176,200,Mucosal inflammation,Gastrointestinal disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005823,S00326,141,144,Diarrhoea,Gastrointestinal disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005824,S00326,333,334,Sepsis,Infections and infestations,4,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0005825,S00326,568,577,Sepsis,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005826,S00326,310,317,Diarrhoea,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005827,S00326,236,262,Aphasia,Nervous system disorders,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005828,S00326,325,339,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005829,S00326,112,127,Anaemia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005830,S00326,143,170,Tremor,Nervous system disorders,4,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005831,S00326,428,442,Anaemia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005832,S00326,336,344,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0005833,S00326,687,697,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005834,S00326,449,452,Aphasia,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005835,S00326,207,223,Anaemia,Blood and lymphatic system,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005836,S00326,430,449,Tremor,Nervous system disorders,4,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0005837,S00326,101,127,Cytomegalovirus infection,Infections and infestations,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0005838,S00326,180,183,Pyrexia,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005839,S00326,449,473,Confusional state,Psychiatric disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005840,S00326,180,183,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0005841,S00326,237,256,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005842,S00326,414,430,Complement activation,Immune system disorders,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005843,S00326,144,148,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005844,S00326,182,197,Bilirubin increased,Investigations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005845,S00326,604,609,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005846,S00327,340,357,Aspartate aminotransferase increased,Investigations,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005847,S00327,213,237,Complement activation,Immune system disorders,4,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005848,S00327,456,475,Vomiting,Gastrointestinal disorders,3,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0005849,S00327,595,602,Headache,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005850,S00327,497,523,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005851,S00327,206,235,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005852,S00327,26,35,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005853,S00327,347,355,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005854,S00327,171,182,Nausea,Gastrointestinal disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005855,S00327,516,529,Neutropenia,Blood and lymphatic system,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005856,S00327,602,616,Neutropenia,Blood and lymphatic system,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005857,S00327,50,75,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005858,S00327,98,117,Vomiting,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005859,S00327,651,664,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005860,S00327,137,160,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005861,S00327,222,239,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005862,S00327,176,182,Nausea,Gastrointestinal disorders,3,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0005863,S00327,603,621,Complement activation,Immune system disorders,3,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005864,S00327,558,574,Hypoxia,"Respiratory, thoracic, mediastinal",5,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005865,S00327,260,288,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005866,S00327,69,93,Pyrexia,General disorders,2,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0005867,S00327,243,248,Anaemia,Blood and lymphatic system,5,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005868,S00327,8,20,Aphasia,Nervous system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005869,S00327,582,589,Aphasia,Nervous system disorders,3,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005870,S00327,443,445,Bilirubin increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005871,S00327,112,135,Pyrexia,General disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005872,S00327,361,389,Pyrexia,General disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005873,S00328,464,466,Anaemia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005874,S00328,255,263,Thrombocytopenia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005875,S00328,344,357,Anaemia,Blood and lymphatic system,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005876,S00328,287,290,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005877,S00328,52,53,Thrombocytopenia,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005878,S00328,76,101,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005879,S00328,358,383,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005880,S00328,373,389,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,None,Not recovered,N,0,N,0,N,Y,Y
AE0005881,S00328,194,216,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0005882,S00328,485,491,Mucosal inflammation,Gastrointestinal disorders,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005883,S00328,83,109,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005884,S00328,75,96,Bilirubin increased,Investigations,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005885,S00329,5,22,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0005886,S00329,376,388,Anaemia,Blood and lymphatic system,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0005887,S00329,645,673,Cytomegalovirus infection,Infections and infestations,3,Y,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005888,S00329,66,92,Headache,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005889,S00329,483,484,Seizure,Nervous system disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005890,S00329,583,597,Complement activation,Immune system disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0005891,S00329,497,522,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005892,S00329,542,571,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0005893,S00329,360,383,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005894,S00329,640,657,Vomiting,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005895,S00329,458,468,Cytomegalovirus infection,Infections and infestations,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005896,S00329,600,605,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005897,S00329,396,401,Nausea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005898,S00329,595,606,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005899,S00329,294,302,Bilirubin increased,Investigations,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0005900,S00329,458,470,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0005901,S00329,89,113,Pyrexia,General disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005902,S00329,44,60,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005903,S00329,30,51,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005904,S00329,610,618,Seizure,Nervous system disorders,3,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0005905,S00329,66,95,Diarrhoea,Gastrointestinal disorders,3,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005906,S00329,95,119,Hypotension,Vascular disorders,1,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0005907,S00329,709,732,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005908,S00329,594,616,Tremor,Nervous system disorders,2,N,N,None,Fatal,N,0,N,0,N,N,N
AE0005909,S00329,450,470,Confusional state,Psychiatric disorders,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005910,S00330,34,35,Cytomegalovirus infection,Infections and infestations,5,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005911,S00330,287,290,Tachycardia,Cardiac disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005912,S00330,419,441,Bilirubin increased,Investigations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005913,S00330,349,376,Hypotension,Vascular disorders,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0005914,S00330,575,594,Sepsis,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005915,S00330,491,507,Fatigue,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005916,S00330,229,246,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005917,S00330,209,223,Confusional state,Psychiatric disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005918,S00330,25,37,Fatigue,General disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0005919,S00330,496,502,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005920,S00330,495,505,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005921,S00330,202,206,Aphasia,Nervous system disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0005922,S00330,437,444,Sepsis,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005923,S00330,183,210,Hypotension,Vascular disorders,4,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005924,S00330,92,113,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005925,S00330,467,484,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0005926,S00330,532,535,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005927,S00330,106,118,Diarrhoea,Gastrointestinal disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005928,S00330,658,685,Sepsis,Infections and infestations,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0005929,S00330,214,220,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005930,S00330,536,564,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005931,S00330,205,213,Fatigue,General disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005932,S00330,726,742,Headache,Nervous system disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005933,S00330,514,524,Seizure,Nervous system disorders,3,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0005934,S00330,391,398,Hypoxia,"Respiratory, thoracic, mediastinal",5,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005935,S00330,439,446,Complement activation,Immune system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005936,S00330,514,522,Tachycardia,Cardiac disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005937,S00330,307,320,Fatigue,General disorders,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0005938,S00330,467,495,Complement activation,Immune system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005939,S00331,407,430,Fatigue,General disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005940,S00331,132,155,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0005941,S00331,563,583,Thrombotic microangiopathy,Blood and lymphatic system,5,Y,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0005942,S00331,322,333,Headache,Nervous system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005943,S00331,63,71,Alanine aminotransferase increased,Investigations,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005944,S00331,14,31,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005945,S00331,641,661,Bilirubin increased,Investigations,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005946,S00331,53,64,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005947,S00331,219,220,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005948,S00331,320,340,Aphasia,Nervous system disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005949,S00331,238,245,Hypotension,Vascular disorders,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0005950,S00331,698,716,Alanine aminotransferase increased,Investigations,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005951,S00331,467,492,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005952,S00331,472,485,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005953,S00331,283,299,Seizure,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005954,S00331,177,194,Neutropenia,Blood and lymphatic system,4,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005955,S00331,288,316,Seizure,Nervous system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0005956,S00331,542,550,Alanine aminotransferase increased,Investigations,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0005957,S00331,298,306,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005958,S00331,306,317,Tachycardia,Cardiac disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0005959,S00331,175,199,Cytomegalovirus infection,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005960,S00331,319,334,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005961,S00331,32,40,Vomiting,Gastrointestinal disorders,3,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0005962,S00331,269,271,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005963,S00331,604,607,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005964,S00331,314,319,Aphasia,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005965,S00331,407,428,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005966,S00331,332,347,Cytomegalovirus infection,Infections and infestations,3,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0005967,S00331,187,207,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0005968,S00332,133,159,Bilirubin increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005969,S00332,215,223,Aspartate aminotransferase increased,Investigations,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005970,S00332,336,344,Tremor,Nervous system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005971,S00332,433,441,Aspartate aminotransferase increased,Investigations,3,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0005972,S00332,540,549,Aspartate aminotransferase increased,Investigations,3,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0005973,S00332,379,387,Bilirubin increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005974,S00332,634,647,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005975,S00332,647,672,Pyrexia,General disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005976,S00332,616,634,Anaemia,Blood and lymphatic system,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0005977,S00332,575,576,Vomiting,Gastrointestinal disorders,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005978,S00332,549,560,Complement activation,Immune system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005979,S00333,5,8,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0005980,S00333,13,32,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0005981,S00333,623,649,Sepsis,Infections and infestations,3,Y,Y,None,Not recovered,N,0,N,0,N,N,N
AE0005982,S00333,618,627,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005983,S00333,611,637,Hypotension,Vascular disorders,4,Y,Y,None,Recovering,N,0,N,0,N,N,N
AE0005984,S00333,91,104,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,None,Recovering,N,0,N,0,N,Y,Y
AE0005985,S00333,122,131,Alanine aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005986,S00333,353,359,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005987,S00333,674,702,Vomiting,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0005988,S00333,346,364,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0005989,S00333,329,331,Bilirubin increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005990,S00333,710,716,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0005991,S00333,450,456,Confusional state,Psychiatric disorders,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0005992,S00333,163,178,Sepsis,Infections and infestations,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0005993,S00333,74,94,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0005994,S00333,130,149,Anaemia,Blood and lymphatic system,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0005995,S00333,231,235,Hypotension,Vascular disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005996,S00333,473,499,Headache,Nervous system disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0005997,S00333,134,138,Nausea,Gastrointestinal disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005998,S00333,39,63,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0005999,S00333,308,330,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,Dose modification,Recovered,N,0,N,0,N,Y,Y
AE0006000,S00333,347,349,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006001,S00333,189,212,Aspartate aminotransferase increased,Investigations,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006002,S00333,20,32,Tremor,Nervous system disorders,1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0006003,S00333,285,306,Pyrexia,General disorders,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006004,S00333,157,161,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0006005,S00333,193,210,Headache,Nervous system disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0006006,S00333,361,364,Hypoxia,"Respiratory, thoracic, mediastinal",5,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006007,S00334,7,21,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0006008,S00334,12,15,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,2,N,Y,Corticosteroids,Recovered,N,0,Y,2,N,N,Y
AE0006009,S00334,42,57,Fatigue,General disorders,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0006010,S00334,123,138,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0006011,S00334,638,660,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0006012,S00334,716,729,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006013,S00334,719,722,Alanine aminotransferase increased,Investigations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006014,S00334,690,715,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006015,S00334,306,317,Mucosal inflammation,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006016,S00334,436,458,Bilirubin increased,Investigations,3,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0006017,S00334,167,192,Confusional state,Psychiatric disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006018,S00334,88,89,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006019,S00334,359,388,Tremor,Nervous system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006020,S00334,168,180,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006021,S00334,246,264,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006022,S00334,235,262,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0006023,S00334,562,567,Tremor,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006024,S00334,686,699,Aphasia,Nervous system disorders,4,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006025,S00334,195,213,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006026,S00334,708,718,Hypogammaglobulinaemia,Immune system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006027,S00334,704,728,Vomiting,Gastrointestinal disorders,2,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0006028,S00334,431,454,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006029,S00334,460,473,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006030,S00334,711,718,Confusional state,Psychiatric disorders,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006031,S00334,331,356,Tremor,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006032,S00334,34,59,Aspartate aminotransferase increased,Investigations,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0006033,S00334,689,697,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006034,S00334,561,565,Neutropenia,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006035,S00334,12,14,Hypotension,Vascular disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006036,S00334,672,689,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006037,S00334,576,588,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006038,S00334,130,140,Aspartate aminotransferase increased,Investigations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006039,S00334,12,13,Anaemia,Blood and lymphatic system,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006040,S00334,188,202,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006041,S00334,115,120,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006042,S00334,74,103,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006043,S00334,400,425,Tremor,Nervous system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006044,S00334,586,603,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006045,S00334,284,304,Tachycardia,Cardiac disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006046,S00334,583,609,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Recovering,N,0,N,0,N,Y,Y
AE0006047,S00334,177,188,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006048,S00334,584,608,Anaemia,Blood and lymphatic system,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006049,S00335,61,67,Neutropenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006050,S00335,455,475,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006051,S00335,33,61,Diarrhoea,Gastrointestinal disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006052,S00335,220,244,Sepsis,Infections and infestations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006053,S00335,658,665,Bilirubin increased,Investigations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006054,S00335,266,286,Hypotension,Vascular disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006055,S00335,601,619,Aphasia,Nervous system disorders,4,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006056,S00335,281,290,Cytomegalovirus infection,Infections and infestations,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006057,S00335,206,234,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006058,S00335,508,519,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006059,S00335,580,595,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006060,S00335,634,655,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006061,S00336,211,233,Thrombotic microangiopathy,Blood and lymphatic system,3,Y,Y,Hospitalization,Recovered,N,0,N,0,N,Y,Y
AE0006062,S00336,452,460,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006063,S00336,133,151,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006064,S00336,502,531,Hypotension,Vascular disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006065,S00336,29,46,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,None,Not recovered,N,0,N,0,N,Y,Y
AE0006066,S00336,242,250,Vomiting,Gastrointestinal disorders,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006067,S00336,240,248,Bilirubin increased,Investigations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006068,S00336,63,76,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006069,S00336,666,683,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006070,S00337,31,50,Hepatocellular injury,Hepatobiliary disorders,5,Y,Y,Tocilizumab,Recovered,Y,0,N,0,Y,N,Y
AE0006071,S00337,417,427,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0006072,S00337,470,490,Aphasia,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006073,S00337,390,412,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006074,S00337,712,736,Alanine aminotransferase increased,Investigations,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006075,S00337,669,673,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006076,S00337,669,682,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006077,S00337,45,53,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006078,S00337,610,612,Hypotension,Vascular disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006079,S00337,720,727,Anaemia,Blood and lymphatic system,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006080,S00337,106,135,Aphasia,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006081,S00337,291,314,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006082,S00338,2,15,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0006083,S00338,12,30,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,3,Y,Y,Corticosteroids,Recovered,N,0,Y,3,N,N,Y
AE0006084,S00338,172,192,Headache,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006085,S00338,693,706,Diarrhoea,Gastrointestinal disorders,3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006086,S00338,442,448,Hypotension,Vascular disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006087,S00338,349,360,Confusional state,Psychiatric disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006088,S00338,149,164,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006089,S00338,346,361,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006090,S00338,203,223,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006091,S00338,654,658,Aphasia,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006092,S00338,298,326,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0006093,S00338,340,363,Seizure,Nervous system disorders,3,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006094,S00338,711,732,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006095,S00338,312,337,Aphasia,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006096,S00338,659,684,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006097,S00338,657,664,Hypotension,Vascular disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006098,S00338,308,322,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006099,S00338,248,257,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006100,S00338,21,36,Cytomegalovirus infection,Infections and infestations,2,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006101,S00338,537,557,Headache,Nervous system disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006102,S00338,295,322,Bilirubin increased,Investigations,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0006103,S00338,427,431,Fatigue,General disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006104,S00338,288,289,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006105,S00338,0,16,Diarrhoea,Gastrointestinal disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006106,S00338,523,542,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0006107,S00338,701,721,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0006108,S00338,190,213,Aphasia,Nervous system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006109,S00338,237,238,Pyrexia,General disorders,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006110,S00338,458,462,Diarrhoea,Gastrointestinal disorders,4,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006111,S00338,500,505,Vomiting,Gastrointestinal disorders,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0006112,S00338,39,40,Fatigue,General disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006113,S00338,333,354,Alanine aminotransferase increased,Investigations,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0006114,S00338,215,226,Complement activation,Immune system disorders,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0006115,S00338,99,120,Tremor,Nervous system disorders,4,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0006116,S00338,547,568,Nausea,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006117,S00340,8,27,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,3,Y,Y,Corticosteroids,Recovered,N,0,Y,3,N,N,Y
AE0006118,S00340,384,402,Cytomegalovirus infection,Infections and infestations,3,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0006119,S00340,170,194,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006120,S00340,227,230,Hypotension,Vascular disorders,3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006121,S00340,488,503,Thrombocytopenia,Blood and lymphatic system,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006122,S00340,423,431,Confusional state,Psychiatric disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006123,S00340,530,550,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006124,S00340,640,652,Confusional state,Psychiatric disorders,4,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006125,S00340,515,528,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006126,S00340,478,506,Thrombocytopenia,Blood and lymphatic system,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006127,S00340,637,661,Fatigue,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006128,S00340,121,123,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006129,S00340,335,339,Complement activation,Immune system disorders,5,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0006130,S00340,361,389,Seizure,Nervous system disorders,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006131,S00340,664,693,Sepsis,Infections and infestations,4,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006132,S00340,578,607,Cytomegalovirus infection,Infections and infestations,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006133,S00340,502,527,Mucosal inflammation,Gastrointestinal disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006134,S00340,46,55,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0006135,S00340,25,29,Neutropenia,Blood and lymphatic system,2,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0006136,S00340,245,256,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0006137,S00340,566,569,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006138,S00340,467,482,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006139,S00340,701,704,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006140,S00340,220,242,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006141,S00340,717,740,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006142,S00340,201,212,Aspartate aminotransferase increased,Investigations,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006143,S00340,156,184,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006144,S00340,108,115,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0006145,S00340,596,612,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006146,S00341,505,508,Tachycardia,Cardiac disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006147,S00341,451,453,Vomiting,Gastrointestinal disorders,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0006148,S00341,339,341,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0006149,S00341,608,612,Mucosal inflammation,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006150,S00341,650,679,Complement activation,Immune system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006151,S00341,553,558,Complement activation,Immune system disorders,1,N,Y,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0006152,S00341,231,250,Nausea,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006153,S00341,709,731,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006154,S00341,550,563,Seizure,Nervous system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006155,S00341,715,735,Anaemia,Blood and lymphatic system,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006156,S00341,547,562,Hypotension,Vascular disorders,3,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006157,S00341,359,375,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0006158,S00341,702,705,Bilirubin increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006159,S00341,497,506,Sepsis,Infections and infestations,5,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0006160,S00341,63,89,Diarrhoea,Gastrointestinal disorders,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006161,S00341,203,217,Fatigue,General disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006162,S00342,232,244,Fatigue,General disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006163,S00342,297,300,Alanine aminotransferase increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006164,S00342,329,358,Neutropenia,Blood and lymphatic system,4,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006165,S00342,300,321,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006166,S00342,143,160,Aphasia,Nervous system disorders,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006167,S00342,358,364,Fatigue,General disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006168,S00342,358,365,Headache,Nervous system disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006169,S00342,359,388,Seizure,Nervous system disorders,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0006170,S00342,231,256,Fatigue,General disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006171,S00342,406,418,Infusion related reaction,"Injury, poisoning, procedural",3,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0006172,S00342,213,225,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006173,S00342,268,295,Fatigue,General disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006174,S00342,15,21,Hypotension,Vascular disorders,4,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006175,S00342,598,622,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006176,S00342,313,335,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006177,S00342,152,166,Fatigue,General disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006178,S00342,118,123,Thrombocytopenia,Blood and lymphatic system,3,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0006179,S00342,52,63,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006180,S00342,129,131,Diarrhoea,Gastrointestinal disorders,2,N,N,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0006181,S00342,626,642,Vomiting,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006182,S00342,585,605,Confusional state,Psychiatric disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006183,S00343,5,9,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0006184,S00343,8,26,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0006185,S00343,252,266,Complement activation,Immune system disorders,2,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0006186,S00343,144,173,Confusional state,Psychiatric disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006187,S00343,624,650,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006188,S00343,296,319,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006189,S00343,217,230,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006190,S00343,291,320,Tremor,Nervous system disorders,3,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0006191,S00343,83,99,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006192,S00343,118,143,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006193,S00343,436,455,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006194,S00343,200,207,Headache,Nervous system disorders,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006195,S00343,597,618,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006196,S00343,413,421,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006197,S00343,56,66,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0006198,S00343,493,494,Alanine aminotransferase increased,Investigations,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0006199,S00343,496,502,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0006200,S00343,717,740,Hypotension,Vascular disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006201,S00343,1,8,Fatigue,General disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006202,S00343,446,472,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006203,S00343,246,267,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006204,S00343,322,350,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006205,S00343,309,313,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006206,S00343,114,136,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006207,S00343,144,152,Complement activation,Immune system disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006208,S00343,416,421,Cytomegalovirus infection,Infections and infestations,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006209,S00343,224,228,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0006210,S00343,542,543,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006211,S00343,302,308,Tremor,Nervous system disorders,4,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006212,S00343,503,505,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006213,S00343,227,230,Neutropenia,Blood and lymphatic system,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006214,S00343,23,31,Hypotension,Vascular disorders,4,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0006215,S00343,471,493,Sepsis,Infections and infestations,5,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006216,S00344,259,283,Hypotension,Vascular disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006217,S00344,87,115,Aspartate aminotransferase increased,Investigations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006218,S00344,589,607,Cytomegalovirus infection,Infections and infestations,4,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006219,S00344,726,744,Vomiting,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006220,S00344,202,216,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006221,S00344,365,385,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006222,S00344,381,410,Anaemia,Blood and lymphatic system,4,N,N,Dose modification,Unknown,N,0,N,0,N,N,N
AE0006223,S00344,464,481,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006224,S00344,69,75,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006225,S00344,251,257,Fatigue,General disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006226,S00344,479,493,Complement activation,Immune system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006227,S00344,48,65,Complement activation,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006228,S00345,6,13,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0006229,S00345,497,519,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006230,S00345,51,60,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006231,S00345,264,288,Anaemia,Blood and lymphatic system,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006232,S00345,414,433,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006233,S00345,501,520,Aphasia,Nervous system disorders,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006234,S00345,672,680,Nausea,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006235,S00345,234,247,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006236,S00345,713,739,Mucosal inflammation,Gastrointestinal disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006237,S00345,36,51,Complement activation,Immune system disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006238,S00345,480,497,Complement activation,Immune system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006239,S00345,516,543,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006240,S00345,253,260,Neutropenia,Blood and lymphatic system,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0006241,S00345,530,550,Thrombocytopenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006242,S00345,90,102,Thrombocytopenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0006243,S00345,588,615,Anaemia,Blood and lymphatic system,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006244,S00345,254,279,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0006245,S00346,3,10,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0006246,S00346,6,8,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,2,N,Y,Corticosteroids,Recovered,N,0,Y,2,N,N,Y
AE0006247,S00346,564,581,Seizure,Nervous system disorders,3,Y,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006248,S00346,36,59,Thrombotic microangiopathy,Blood and lymphatic system,3,Y,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0006249,S00346,361,364,Thrombocytopenia,Blood and lymphatic system,1,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0006250,S00346,383,391,Anaemia,Blood and lymphatic system,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006251,S00346,349,360,Fatigue,General disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006252,S00346,236,258,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Unknown,N,0,N,0,N,Y,Y
AE0006253,S00346,469,489,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0006254,S00346,545,565,Nausea,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006255,S00346,156,183,Bilirubin increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006256,S00346,131,132,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006257,S00346,658,675,Headache,Nervous system disorders,1,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0006258,S00346,636,640,Sepsis,Infections and infestations,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006259,S00346,720,721,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0006260,S00346,439,459,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006261,S00346,73,92,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006262,S00346,483,491,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006263,S00346,641,642,Fatigue,General disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006264,S00346,481,496,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006265,S00346,271,294,Infusion related reaction,"Injury, poisoning, procedural",4,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006266,S00346,71,73,Vomiting,Gastrointestinal disorders,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006267,S00346,619,638,Seizure,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006268,S00346,217,223,Tremor,Nervous system disorders,5,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0006269,S00346,161,167,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006270,S00346,347,358,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006271,S00346,483,494,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006272,S00346,523,545,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006273,S00346,222,225,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006274,S00346,130,131,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006275,S00346,643,670,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006276,S00346,597,623,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006277,S00347,471,479,Tremor,Nervous system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0006278,S00347,703,725,Aspartate aminotransferase increased,Investigations,3,Y,N,None,Not recovered,N,0,N,0,N,N,N
AE0006279,S00347,664,673,Anaemia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006280,S00347,248,273,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006281,S00347,5,10,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006282,S00347,621,637,Anaemia,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006283,S00347,408,422,Confusional state,Psychiatric disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0006284,S00347,169,190,Aspartate aminotransferase increased,Investigations,5,N,N,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0006285,S00347,97,113,Pyrexia,General disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006286,S00347,126,143,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006287,S00347,205,206,Confusional state,Psychiatric disorders,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006288,S00347,530,538,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006289,S00347,259,262,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0006290,S00347,713,729,Seizure,Nervous system disorders,5,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006291,S00347,556,564,Fatigue,General disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006292,S00347,577,606,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0006293,S00347,333,337,Hypotension,Vascular disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006294,S00347,394,395,Cytomegalovirus infection,Infections and infestations,5,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0006295,S00348,181,204,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006296,S00348,222,228,Fatigue,General disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006297,S00348,592,601,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006298,S00348,526,527,Mucosal inflammation,Gastrointestinal disorders,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006299,S00348,528,533,Complement activation,Immune system disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0006300,S00348,211,226,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006301,S00348,546,568,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006302,S00348,506,534,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006303,S00348,437,461,Tachycardia,Cardiac disorders,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006304,S00348,413,423,Neutropenia,Blood and lymphatic system,2,N,N,Dose modification,Unknown,N,0,N,0,N,N,N
AE0006305,S00348,564,565,Thrombocytopenia,Blood and lymphatic system,3,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0006306,S00348,399,410,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006307,S00348,175,178,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006308,S00348,601,612,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006309,S00348,367,372,Seizure,Nervous system disorders,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006310,S00348,451,455,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006311,S00348,60,78,Hypotension,Vascular disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006312,S00348,669,698,Alanine aminotransferase increased,Investigations,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006313,S00349,422,436,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006314,S00349,607,631,Alanine aminotransferase increased,Investigations,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006315,S00349,130,150,Infusion related reaction,"Injury, poisoning, procedural",3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006316,S00349,710,728,Anaemia,Blood and lymphatic system,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006317,S00349,364,389,Aspartate aminotransferase increased,Investigations,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006318,S00349,24,46,Anaemia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006319,S00349,686,687,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,Drug interrupted,Fatal,N,0,N,0,N,N,N
AE0006320,S00349,474,496,Neutropenia,Blood and lymphatic system,5,N,N,Dose modification,Unknown,N,0,N,0,N,N,N
AE0006321,S00349,408,429,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0006322,S00350,173,202,Pyrexia,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006323,S00350,283,290,Bilirubin increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006324,S00350,657,658,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006325,S00350,490,502,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006326,S00350,337,366,Pyrexia,General disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006327,S00350,146,171,Pyrexia,General disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006328,S00350,222,238,Tremor,Nervous system disorders,1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0006329,S00350,294,308,Aspartate aminotransferase increased,Investigations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006330,S00350,23,25,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006331,S00350,425,453,Anaemia,Blood and lymphatic system,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006332,S00350,203,216,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006333,S00350,203,223,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006334,S00350,526,540,Aspartate aminotransferase increased,Investigations,5,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006335,S00350,433,455,Seizure,Nervous system disorders,2,N,N,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0006336,S00351,652,672,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006337,S00351,90,105,Cytomegalovirus infection,Infections and infestations,4,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006338,S00351,332,351,Sepsis,Infections and infestations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006339,S00351,646,648,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006340,S00351,320,337,Fatigue,General disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006341,S00351,97,110,Cytomegalovirus infection,Infections and infestations,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006342,S00351,645,670,Seizure,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006343,S00351,555,561,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0006344,S00351,285,291,Anaemia,Blood and lymphatic system,1,N,Y,Dose modification,Unknown,N,0,N,0,N,N,N
AE0006345,S00351,16,40,Fatigue,General disorders,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0006346,S00351,704,732,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006347,S00351,586,594,Tachycardia,Cardiac disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006348,S00352,710,724,Bilirubin increased,Investigations,3,Y,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0006349,S00352,237,246,Bilirubin increased,Investigations,2,N,N,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0006350,S00352,443,453,Seizure,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006351,S00352,644,669,Aphasia,Nervous system disorders,5,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0006352,S00352,566,586,Hypotension,Vascular disorders,3,Y,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0006353,S00352,695,704,Fatigue,General disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006354,S00352,9,23,Pyrexia,General disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006355,S00352,493,505,Tremor,Nervous system disorders,3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006356,S00352,71,96,Thrombocytopenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006357,S00352,239,257,Thrombocytopenia,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006358,S00352,179,190,Thrombocytopenia,Blood and lymphatic system,5,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006359,S00352,37,53,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0006360,S00353,729,756,Cytomegalovirus infection,Infections and infestations,3,Y,Y,None,Recovering,N,0,N,0,N,N,N
AE0006361,S00353,627,631,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006362,S00353,607,626,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006363,S00353,166,190,Aphasia,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006364,S00353,62,65,Nausea,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006365,S00353,137,165,Confusional state,Psychiatric disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006366,S00353,32,37,Neutropenia,Blood and lymphatic system,5,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006367,S00353,488,513,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006368,S00354,366,371,Complement activation,Immune system disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0006369,S00354,602,630,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,Hospitalization,Recovered,N,0,N,0,N,Y,Y
AE0006370,S00354,419,447,Sepsis,Infections and infestations,3,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006371,S00354,568,589,Vomiting,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006372,S00354,646,648,Aphasia,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006373,S00354,297,325,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006374,S00354,714,742,Seizure,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006375,S00354,572,587,Aphasia,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006376,S00354,14,24,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0006377,S00354,141,144,Nausea,Gastrointestinal disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006378,S00354,645,652,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006379,S00354,467,483,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006380,S00354,374,380,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006381,S00355,291,299,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0006382,S00355,651,654,Confusional state,Psychiatric disorders,4,N,N,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0006383,S00355,203,211,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006384,S00355,656,662,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006385,S00355,662,664,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0006386,S00355,545,562,Bilirubin increased,Investigations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006387,S00355,341,350,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0006388,S00355,505,509,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Unknown,N,0,N,0,N,Y,Y
AE0006389,S00355,526,541,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006390,S00355,622,635,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006391,S00355,257,284,Confusional state,Psychiatric disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006392,S00355,717,729,Aphasia,Nervous system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006393,S00355,12,22,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0006394,S00356,368,381,Seizure,Nervous system disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0006395,S00356,199,219,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0006396,S00356,232,235,Bilirubin increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006397,S00356,681,696,Hypogammaglobulinaemia,Immune system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006398,S00356,126,143,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006399,S00356,395,397,Thrombocytopenia,Blood and lymphatic system,3,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0006400,S00356,642,647,Headache,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006401,S00356,61,86,Sepsis,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006402,S00356,619,625,Seizure,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006403,S00356,475,502,Anaemia,Blood and lymphatic system,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006404,S00357,6,9,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0006405,S00357,696,722,Hypoxia,"Respiratory, thoracic, mediastinal",5,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0006406,S00357,197,198,Fatigue,General disorders,3,Y,N,None,Recovering,N,0,N,0,N,N,N
AE0006407,S00357,93,120,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006408,S00357,585,586,Complement activation,Immune system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006409,S00357,296,318,Aspartate aminotransferase increased,Investigations,3,Y,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006410,S00357,106,109,Tremor,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006411,S00357,254,272,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006412,S00357,382,404,Aphasia,Nervous system disorders,5,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006413,S00357,698,712,Nausea,Gastrointestinal disorders,1,N,N,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0006414,S00357,203,229,Fatigue,General disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006415,S00357,203,223,Headache,Nervous system disorders,1,N,N,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0006416,S00357,232,254,Infusion related reaction,"Injury, poisoning, procedural",3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006417,S00357,198,205,Bilirubin increased,Investigations,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006418,S00357,87,92,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006419,S00357,368,369,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006420,S00357,108,124,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006421,S00357,433,457,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006422,S00357,424,433,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006423,S00357,357,372,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006424,S00357,199,215,Tachycardia,Cardiac disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006425,S00357,59,69,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006426,S00358,7,23,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0006427,S00358,10,12,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,2,N,Y,Corticosteroids,Recovered,N,0,Y,2,N,N,Y
AE0006428,S00358,558,568,Vomiting,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006429,S00358,672,674,Cytomegalovirus infection,Infections and infestations,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0006430,S00358,82,105,Tremor,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006431,S00358,478,503,Pyrexia,General disorders,3,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0006432,S00358,74,103,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006433,S00358,403,413,Fatigue,General disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006434,S00358,328,348,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006435,S00358,112,137,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0006436,S00358,726,728,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0006437,S00358,221,234,Thrombocytopenia,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006438,S00358,227,242,Thrombocytopenia,Blood and lymphatic system,3,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006439,S00358,582,600,Neutropenia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006440,S00358,284,299,Sepsis,Infections and infestations,3,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0006441,S00358,709,733,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006442,S00358,329,338,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0006443,S00358,201,203,Thrombocytopenia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006444,S00358,348,375,Cough,"Respiratory, thoracic, mediastinal",2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006445,S00358,205,213,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0006446,S00358,438,447,Pyrexia,General disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0006447,S00358,594,596,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006448,S00358,184,188,Seizure,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006449,S00358,231,250,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006450,S00358,81,87,Headache,Nervous system disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006451,S00358,558,562,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006452,S00359,60,67,Cough,"Respiratory, thoracic, mediastinal",3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006453,S00359,459,482,Cough,"Respiratory, thoracic, mediastinal",3,Y,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006454,S00359,98,99,Aspartate aminotransferase increased,Investigations,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006455,S00359,322,335,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006456,S00359,638,639,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006457,S00359,17,46,Seizure,Nervous system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006458,S00359,154,176,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006459,S00359,503,519,Aspartate aminotransferase increased,Investigations,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006460,S00359,242,261,Bilirubin increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006461,S00360,258,278,Pyrexia,General disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006462,S00360,639,650,Cytomegalovirus infection,Infections and infestations,3,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006463,S00360,346,369,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006464,S00360,278,298,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0006465,S00360,326,341,Hypotension,Vascular disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006466,S00360,628,652,Headache,Nervous system disorders,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0006467,S00360,259,260,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006468,S00360,33,60,Aspartate aminotransferase increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006469,S00361,4,22,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0006470,S00361,13,32,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,3,Y,Y,Corticosteroids,Recovered,N,0,Y,3,N,N,Y
AE0006471,S00361,218,245,Neutropenia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006472,S00361,34,45,Bilirubin increased,Investigations,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006473,S00361,479,503,Diarrhoea,Gastrointestinal disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006474,S00361,607,626,Aphasia,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006475,S00361,653,659,Aphasia,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006476,S00361,697,703,Bilirubin increased,Investigations,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006477,S00361,450,470,Cough,"Respiratory, thoracic, mediastinal",2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006478,S00361,415,424,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006479,S00361,239,241,Thrombocytopenia,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006480,S00361,160,176,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006481,S00361,537,546,Sepsis,Infections and infestations,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0006482,S00361,39,60,Tachycardia,Cardiac disorders,3,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0006483,S00361,292,309,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006484,S00361,399,411,Seizure,Nervous system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006485,S00361,405,424,Confusional state,Psychiatric disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006486,S00361,235,261,Aphasia,Nervous system disorders,3,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0006487,S00361,89,95,Aphasia,Nervous system disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006488,S00361,384,398,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006489,S00361,603,610,Fatigue,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006490,S00361,519,537,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006491,S00362,175,198,Cough,"Respiratory, thoracic, mediastinal",3,Y,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006492,S00362,452,477,Alanine aminotransferase increased,Investigations,3,Y,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006493,S00362,48,67,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006494,S00362,48,58,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0006495,S00362,501,516,Pyrexia,General disorders,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0006496,S00362,473,483,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006497,S00362,493,508,Alanine aminotransferase increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006498,S00362,391,417,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006499,S00362,490,513,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006500,S00362,233,240,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006501,S00362,515,517,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006502,S00362,600,611,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0006503,S00362,711,722,Fatigue,General disorders,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006504,S00363,350,363,Bilirubin increased,Investigations,3,Y,N,None,Recovering,N,0,N,0,N,N,N
AE0006505,S00363,544,566,Confusional state,Psychiatric disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006506,S00363,714,742,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006507,S00363,345,352,Aphasia,Nervous system disorders,5,N,N,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0006508,S00363,660,682,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006509,S00363,44,69,Alanine aminotransferase increased,Investigations,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0006510,S00363,27,46,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006511,S00363,12,19,Headache,Nervous system disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006512,S00363,386,411,Tremor,Nervous system disorders,1,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0006513,S00363,160,168,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006514,S00363,654,681,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006515,S00363,604,631,Aphasia,Nervous system disorders,2,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0006516,S00363,111,116,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006517,S00363,633,649,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006518,S00365,6,14,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0006519,S00365,282,291,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006520,S00365,440,458,Alanine aminotransferase increased,Investigations,3,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0006521,S00365,40,45,Mucosal inflammation,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006522,S00365,195,200,Confusional state,Psychiatric disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006523,S00365,654,680,Hypogammaglobulinaemia,Immune system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006524,S00365,264,278,Anaemia,Blood and lymphatic system,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006525,S00365,625,637,Neutropenia,Blood and lymphatic system,1,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0006526,S00365,251,262,Thrombocytopenia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006527,S00365,277,305,Anaemia,Blood and lymphatic system,3,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0006528,S00365,557,566,Complement activation,Immune system disorders,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0006529,S00365,470,479,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006530,S00365,550,559,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006531,S00365,454,470,Alanine aminotransferase increased,Investigations,1,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0006532,S00365,82,99,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0006533,S00365,562,588,Nausea,Gastrointestinal disorders,3,N,Y,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0006534,S00365,88,103,Complement activation,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006535,S00365,680,690,Alanine aminotransferase increased,Investigations,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006536,S00365,89,101,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006537,S00365,618,639,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006538,S00365,658,677,Cytomegalovirus infection,Infections and infestations,1,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0006539,S00365,377,397,Bilirubin increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006540,S00365,625,651,Thrombocytopenia,Blood and lymphatic system,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006541,S00365,520,530,Bilirubin increased,Investigations,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006542,S00365,115,122,Thrombocytopenia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006543,S00365,314,325,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006544,S00365,494,522,Neutropenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006545,S00365,403,416,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006546,S00365,573,577,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006547,S00365,513,538,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006548,S00366,64,75,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006549,S00366,173,179,Neutropenia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006550,S00366,205,231,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006551,S00366,595,623,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006552,S00366,624,653,Seizure,Nervous system disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006553,S00366,518,539,Nausea,Gastrointestinal disorders,4,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0006554,S00366,607,628,Vomiting,Gastrointestinal disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006555,S00367,7,18,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0006556,S00367,79,84,Mucosal inflammation,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006557,S00367,613,635,Aphasia,Nervous system disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006558,S00367,674,701,Thrombocytopenia,Blood and lymphatic system,3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006559,S00367,712,718,Nausea,Gastrointestinal disorders,2,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0006560,S00367,613,615,Cough,"Respiratory, thoracic, mediastinal",3,Y,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006561,S00367,354,370,Pyrexia,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006562,S00367,95,97,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006563,S00367,21,49,Fatigue,General disorders,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006564,S00367,677,703,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006565,S00367,498,501,Hypotension,Vascular disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006566,S00367,299,301,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006567,S00367,483,510,Bilirubin increased,Investigations,5,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006568,S00367,113,121,Diarrhoea,Gastrointestinal disorders,3,N,Y,Hospitalization,Fatal,N,0,N,0,N,N,N
AE0006569,S00367,372,399,Bilirubin increased,Investigations,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006570,S00367,475,496,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006571,S00367,497,501,Tremor,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006572,S00367,547,569,Sepsis,Infections and infestations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006573,S00367,108,132,Alanine aminotransferase increased,Investigations,4,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006574,S00367,304,330,Cytomegalovirus infection,Infections and infestations,5,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006575,S00367,234,250,Cytomegalovirus infection,Infections and infestations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006576,S00367,290,308,Aphasia,Nervous system disorders,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006577,S00367,719,741,Fatigue,General disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006578,S00367,662,665,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006579,S00367,399,400,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0006580,S00367,727,755,Tachycardia,Cardiac disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006581,S00367,329,358,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006582,S00367,213,229,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006583,S00367,177,184,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006584,S00367,131,145,Vomiting,Gastrointestinal disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006585,S00367,74,94,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0006586,S00367,17,24,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006587,S00367,629,637,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006588,S00367,438,466,Fatigue,General disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006589,S00368,6,23,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0006590,S00368,194,216,Bilirubin increased,Investigations,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006591,S00368,26,48,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0006592,S00368,586,595,Headache,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006593,S00368,326,345,Vomiting,Gastrointestinal disorders,2,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006594,S00368,212,221,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006595,S00368,606,615,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,None,Not recovered,N,0,N,0,N,Y,Y
AE0006596,S00368,576,584,Pyrexia,General disorders,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006597,S00368,39,65,Vomiting,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006598,S00368,120,133,Diarrhoea,Gastrointestinal disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006599,S00368,7,29,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006600,S00368,445,450,Diarrhoea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0006601,S00368,195,212,Hypotension,Vascular disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006602,S00368,60,80,Aspartate aminotransferase increased,Investigations,5,N,Y,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0006603,S00368,252,276,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006604,S00368,446,461,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006605,S00368,25,27,Thrombocytopenia,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006606,S00368,715,739,Fatigue,General disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006607,S00368,445,464,Hypotension,Vascular disorders,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0006608,S00368,653,680,Pyrexia,General disorders,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0006609,S00368,62,71,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006610,S00368,514,522,Fatigue,General disorders,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006611,S00368,329,352,Mucosal inflammation,Gastrointestinal disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006612,S00369,10,34,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006613,S00369,657,667,Hypotension,Vascular disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006614,S00369,273,293,Headache,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006615,S00369,493,515,Tachycardia,Cardiac disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006616,S00369,371,385,Mucosal inflammation,Gastrointestinal disorders,5,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0006617,S00369,506,511,Aphasia,Nervous system disorders,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0006618,S00369,682,711,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006619,S00369,642,658,Hypotension,Vascular disorders,4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006620,S00369,45,54,Aspartate aminotransferase increased,Investigations,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006621,S00369,241,247,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006622,S00369,606,609,Bilirubin increased,Investigations,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006623,S00369,513,522,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006624,S00369,121,142,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Unknown,N,0,N,0,N,Y,Y
AE0006625,S00369,179,184,Tachycardia,Cardiac disorders,3,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006626,S00369,521,533,Tremor,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006627,S00369,178,200,Vomiting,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006628,S00370,3,7,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0006629,S00370,4,11,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,2,N,Y,Corticosteroids,Recovered,N,0,Y,2,N,N,Y
AE0006630,S00370,700,724,Sepsis,Infections and infestations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006631,S00370,478,494,Nausea,Gastrointestinal disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006632,S00370,718,727,Seizure,Nervous system disorders,3,Y,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006633,S00370,538,548,Seizure,Nervous system disorders,2,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0006634,S00370,646,649,Thrombocytopenia,Blood and lymphatic system,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006635,S00370,621,641,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006636,S00370,213,222,Mucosal inflammation,Gastrointestinal disorders,3,Y,N,None,Fatal,N,0,N,0,N,N,N
AE0006637,S00370,77,100,Sepsis,Infections and infestations,3,Y,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006638,S00370,554,557,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006639,S00370,726,753,Tremor,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006640,S00370,133,138,Tachycardia,Cardiac disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006641,S00370,236,253,Seizure,Nervous system disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0006642,S00370,711,735,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,None,Recovering,N,0,N,0,N,Y,Y
AE0006643,S00370,23,47,Thrombocytopenia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006644,S00370,712,733,Neutropenia,Blood and lymphatic system,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0006645,S00370,375,398,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006646,S00370,508,531,Sepsis,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006647,S00370,255,281,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Hospitalization,Recovered,N,0,N,0,N,Y,Y
AE0006648,S00370,551,561,Aphasia,Nervous system disorders,2,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0006649,S00370,500,517,Pyrexia,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006650,S00370,710,715,Thrombocytopenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006651,S00370,330,351,Diarrhoea,Gastrointestinal disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006652,S00370,550,566,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006653,S00370,460,467,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,Y,Y
AE0006654,S00371,6,9,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0006655,S00371,365,367,Alanine aminotransferase increased,Investigations,5,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006656,S00371,256,279,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006657,S00371,255,283,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006658,S00371,628,633,Tremor,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006659,S00371,89,92,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006660,S00371,291,306,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006661,S00371,392,399,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006662,S00371,160,170,Aphasia,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006663,S00371,667,671,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006664,S00371,706,734,Alanine aminotransferase increased,Investigations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006665,S00371,232,260,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006666,S00371,39,42,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0006667,S00371,704,721,Sepsis,Infections and infestations,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006668,S00371,309,325,Nausea,Gastrointestinal disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006669,S00371,97,107,Nausea,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006670,S00371,100,128,Seizure,Nervous system disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006671,S00371,310,332,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0006672,S00371,278,304,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006673,S00371,57,78,Seizure,Nervous system disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006674,S00371,118,131,Pyrexia,General disorders,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006675,S00371,465,493,Confusional state,Psychiatric disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006676,S00371,688,713,Alanine aminotransferase increased,Investigations,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006677,S00371,678,694,Neutropenia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006678,S00371,413,440,Tremor,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006679,S00371,173,184,Aphasia,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006680,S00371,552,553,Aphasia,Nervous system disorders,3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006681,S00371,187,197,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006682,S00371,25,27,Nausea,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006683,S00371,164,186,Aphasia,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006684,S00371,550,559,Confusional state,Psychiatric disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0006685,S00371,566,586,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0006686,S00371,410,419,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006687,S00372,457,459,Headache,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006688,S00372,703,707,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0006689,S00372,319,346,Hypotension,Vascular disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006690,S00372,392,411,Bilirubin increased,Investigations,4,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0006691,S00372,619,638,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006692,S00372,694,708,Neutropenia,Blood and lymphatic system,4,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0006693,S00372,158,168,Aphasia,Nervous system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006694,S00372,425,432,Fatigue,General disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006695,S00372,298,315,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006696,S00372,408,414,Alanine aminotransferase increased,Investigations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006697,S00372,392,421,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006698,S00372,3,23,Cytomegalovirus infection,Infections and infestations,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006699,S00372,702,726,Tremor,Nervous system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006700,S00372,166,183,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006701,S00372,635,661,Pyrexia,General disorders,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006702,S00372,474,476,Confusional state,Psychiatric disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006703,S00372,140,160,Thrombotic microangiopathy,Blood and lymphatic system,5,N,N,Concomitant medication,Recovering,N,0,N,0,N,Y,Y
AE0006704,S00372,650,670,Fatigue,General disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006705,S00372,323,331,Complement activation,Immune system disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006706,S00373,637,650,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006707,S00373,387,392,Neutropenia,Blood and lymphatic system,2,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0006708,S00373,278,289,Sepsis,Infections and infestations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006709,S00373,154,167,Thrombocytopenia,Blood and lymphatic system,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006710,S00373,269,298,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0006711,S00373,431,439,Tremor,Nervous system disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006712,S00373,271,279,Diarrhoea,Gastrointestinal disorders,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006713,S00373,217,234,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006714,S00373,522,526,Tachycardia,Cardiac disorders,1,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0006715,S00373,5,32,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006716,S00373,481,504,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0006717,S00373,585,596,Complement activation,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006718,S00373,173,193,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006719,S00373,448,475,Cytomegalovirus infection,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006720,S00373,415,428,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006721,S00374,579,580,Nausea,Gastrointestinal disorders,3,Y,Y,None,Recovering,N,0,N,0,N,N,N
AE0006722,S00374,267,276,Cytomegalovirus infection,Infections and infestations,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006723,S00374,670,697,Fatigue,General disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006724,S00374,247,254,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006725,S00374,459,462,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,Y,Y
AE0006726,S00374,26,29,Bilirubin increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006727,S00374,319,342,Complement activation,Immune system disorders,2,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0006728,S00374,413,432,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006729,S00374,656,658,Sepsis,Infections and infestations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006730,S00374,87,104,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0006731,S00374,145,173,Confusional state,Psychiatric disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006732,S00374,460,488,Hypotension,Vascular disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006733,S00374,530,537,Diarrhoea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006734,S00374,118,139,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006735,S00374,705,722,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006736,S00374,26,43,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006737,S00374,2,25,Alanine aminotransferase increased,Investigations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006738,S00374,289,292,Hypotension,Vascular disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006739,S00374,248,265,Hypogammaglobulinaemia,Immune system disorders,2,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0006740,S00374,379,381,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Not recovered,N,0,N,0,N,Y,Y
AE0006741,S00375,285,304,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006742,S00375,718,728,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,Y,Y
AE0006743,S00375,653,671,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006744,S00375,182,198,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006745,S00375,256,276,Confusional state,Psychiatric disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006746,S00375,515,534,Sepsis,Infections and infestations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006747,S00377,4,20,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,2,N,Y,Corticosteroids,Recovered,N,0,Y,2,N,N,Y
AE0006748,S00377,606,613,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006749,S00377,262,273,Headache,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006750,S00377,714,729,Headache,Nervous system disorders,3,Y,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006751,S00377,643,652,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006752,S00377,683,705,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006753,S00377,105,129,Neutropenia,Blood and lymphatic system,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006754,S00377,661,674,Bilirubin increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006755,S00377,470,497,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006756,S00377,147,168,Pyrexia,General disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0006757,S00377,421,450,Cytomegalovirus infection,Infections and infestations,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006758,S00377,525,538,Hypotension,Vascular disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006759,S00377,111,128,Sepsis,Infections and infestations,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0006760,S00377,619,642,Fatigue,General disorders,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006761,S00377,315,323,Seizure,Nervous system disorders,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006762,S00377,11,23,Alanine aminotransferase increased,Investigations,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006763,S00377,239,247,Complement activation,Immune system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006764,S00377,276,283,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006765,S00377,223,244,Aspartate aminotransferase increased,Investigations,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006766,S00377,478,491,Nausea,Gastrointestinal disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006767,S00377,452,457,Aphasia,Nervous system disorders,5,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0006768,S00377,385,391,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006769,S00377,506,535,Fatigue,General disorders,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0006770,S00377,290,305,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006771,S00377,397,403,Confusional state,Psychiatric disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006772,S00377,81,98,Seizure,Nervous system disorders,1,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0006773,S00377,622,629,Headache,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006774,S00377,686,713,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0006775,S00377,646,668,Tremor,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006776,S00377,359,364,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006777,S00377,152,177,Fatigue,General disorders,5,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006778,S00377,618,632,Seizure,Nervous system disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006779,S00377,609,630,Cytomegalovirus infection,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006780,S00377,553,566,Sepsis,Infections and infestations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006781,S00377,1,14,Seizure,Nervous system disorders,5,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006782,S00377,225,229,Seizure,Nervous system disorders,4,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006783,S00377,432,434,Thrombocytopenia,Blood and lymphatic system,2,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0006784,S00377,609,638,Complement activation,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006785,S00377,585,611,Complement activation,Immune system disorders,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006786,S00377,509,521,Aspartate aminotransferase increased,Investigations,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006787,S00378,78,81,Hepatocellular injury,Hepatobiliary disorders,3,Y,Y,Tocilizumab,Recovered,Y,0,N,0,Y,N,Y
AE0006788,S00378,256,285,Headache,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006789,S00378,384,405,Bilirubin increased,Investigations,3,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006790,S00378,229,240,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006791,S00378,559,569,Nausea,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006792,S00378,18,19,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006793,S00378,728,757,Aspartate aminotransferase increased,Investigations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006794,S00378,317,325,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006795,S00378,585,605,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006796,S00378,411,437,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006797,S00378,388,401,Tachycardia,Cardiac disorders,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006798,S00378,178,189,Headache,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006799,S00378,50,74,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006800,S00379,714,737,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006801,S00379,223,231,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006802,S00379,149,155,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006803,S00379,649,667,Aphasia,Nervous system disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0006804,S00379,707,724,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006805,S00379,444,462,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,None,Not recovered,N,0,N,0,N,Y,Y
AE0006806,S00379,287,298,Sepsis,Infections and infestations,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006807,S00379,166,183,Anaemia,Blood and lymphatic system,2,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006808,S00379,487,516,Thrombocytopenia,Blood and lymphatic system,5,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006809,S00379,725,735,Hypogammaglobulinaemia,Immune system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006810,S00379,441,452,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0006811,S00379,629,657,Fatigue,General disorders,1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0006812,S00379,291,313,Sepsis,Infections and infestations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006813,S00379,560,582,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,Hospitalization,Recovering,N,0,N,0,N,Y,Y
AE0006814,S00379,503,511,Sepsis,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006815,S00379,77,95,Alanine aminotransferase increased,Investigations,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006816,S00379,711,717,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006817,S00379,260,265,Nausea,Gastrointestinal disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0006818,S00379,310,311,Alanine aminotransferase increased,Investigations,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0006819,S00379,413,439,Tremor,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006820,S00379,490,502,Hypotension,Vascular disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006821,S00380,5,22,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0006822,S00380,3,28,Nausea,Gastrointestinal disorders,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0006823,S00380,192,205,Hypogammaglobulinaemia,Immune system disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0006824,S00380,56,79,Aphasia,Nervous system disorders,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0006825,S00380,79,105,Fatigue,General disorders,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0006826,S00380,293,294,Alanine aminotransferase increased,Investigations,3,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0006827,S00380,92,107,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006828,S00380,235,243,Headache,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006829,S00380,177,200,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006830,S00380,481,504,Sepsis,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006831,S00380,201,229,Nausea,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006832,S00380,527,542,Diarrhoea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0006833,S00380,184,186,Infusion related reaction,"Injury, poisoning, procedural",3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006834,S00380,28,50,Fatigue,General disorders,1,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0006835,S00380,543,562,Anaemia,Blood and lymphatic system,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0006836,S00380,528,532,Neutropenia,Blood and lymphatic system,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006837,S00380,267,293,Diarrhoea,Gastrointestinal disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006838,S00380,675,693,Thrombocytopenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006839,S00380,481,506,Headache,Nervous system disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006840,S00380,140,169,Pyrexia,General disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006841,S00380,415,423,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006842,S00380,599,619,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0006843,S00380,626,633,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0006844,S00380,490,515,Tremor,Nervous system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006845,S00380,13,17,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006846,S00380,552,573,Aspartate aminotransferase increased,Investigations,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006847,S00380,467,479,Aphasia,Nervous system disorders,5,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006848,S00380,72,78,Seizure,Nervous system disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006849,S00381,45,53,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006850,S00381,621,625,Thrombocytopenia,Blood and lymphatic system,4,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0006851,S00381,333,361,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006852,S00381,417,442,Diarrhoea,Gastrointestinal disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006853,S00381,38,44,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006854,S00381,393,404,Complement activation,Immune system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006855,S00381,223,229,Confusional state,Psychiatric disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006856,S00381,394,416,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006857,S00381,164,165,Fatigue,General disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006858,S00381,679,681,Cytomegalovirus infection,Infections and infestations,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006859,S00381,167,196,Neutropenia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006860,S00382,1,15,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0006861,S00382,23,51,Vomiting,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006862,S00382,474,479,Alanine aminotransferase increased,Investigations,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006863,S00382,94,100,Pyrexia,General disorders,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0006864,S00382,315,334,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0006865,S00382,517,535,Aspartate aminotransferase increased,Investigations,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006866,S00382,346,367,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006867,S00382,550,554,Pyrexia,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006868,S00382,524,550,Aspartate aminotransferase increased,Investigations,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0006869,S00382,4,9,Anaemia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006870,S00382,55,84,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006871,S00382,267,280,Cytomegalovirus infection,Infections and infestations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006872,S00382,533,536,Diarrhoea,Gastrointestinal disorders,3,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006873,S00382,359,374,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0006874,S00382,114,115,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006875,S00382,69,94,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006876,S00382,24,47,Neutropenia,Blood and lymphatic system,5,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006877,S00382,482,499,Aphasia,Nervous system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006878,S00382,437,451,Sepsis,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006879,S00382,151,165,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006880,S00382,563,571,Anaemia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006881,S00382,10,26,Pyrexia,General disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0006882,S00382,276,303,Alanine aminotransferase increased,Investigations,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006883,S00382,636,649,Seizure,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006884,S00383,5,11,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0006885,S00383,641,647,Mucosal inflammation,Gastrointestinal disorders,3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006886,S00383,600,606,Thrombocytopenia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006887,S00383,421,424,Confusional state,Psychiatric disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006888,S00383,22,38,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006889,S00383,679,708,Cytomegalovirus infection,Infections and infestations,5,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0006890,S00383,405,427,Cytomegalovirus infection,Infections and infestations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006891,S00383,64,81,Anaemia,Blood and lymphatic system,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006892,S00383,368,371,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006893,S00383,119,137,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Recovering,N,0,N,0,N,Y,Y
AE0006894,S00383,238,255,Hypogammaglobulinaemia,Immune system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006895,S00383,101,106,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0006896,S00383,226,255,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006897,S00383,29,54,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006898,S00383,229,232,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0006899,S00383,523,548,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006900,S00383,38,61,Headache,Nervous system disorders,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0006901,S00383,151,165,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006902,S00383,410,421,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006903,S00383,452,458,Complement activation,Immune system disorders,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006904,S00383,609,618,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006905,S00383,168,192,Diarrhoea,Gastrointestinal disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006906,S00383,579,596,Pyrexia,General disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006907,S00383,603,626,Cytomegalovirus infection,Infections and infestations,5,N,Y,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0006908,S00383,171,172,Seizure,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006909,S00383,554,583,Confusional state,Psychiatric disorders,2,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0006910,S00385,586,613,Diarrhoea,Gastrointestinal disorders,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0006911,S00385,137,150,Complement activation,Immune system disorders,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006912,S00385,395,417,Pyrexia,General disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006913,S00385,658,674,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006914,S00385,585,613,Headache,Nervous system disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006915,S00385,56,75,Seizure,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006916,S00385,601,625,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006917,S00385,725,753,Tremor,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006918,S00385,474,490,Mucosal inflammation,Gastrointestinal disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006919,S00385,362,379,Vomiting,Gastrointestinal disorders,1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0006920,S00385,81,88,Tremor,Nervous system disorders,4,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006921,S00385,15,29,Aspartate aminotransferase increased,Investigations,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006922,S00385,93,121,Aphasia,Nervous system disorders,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006923,S00385,260,269,Complement activation,Immune system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006924,S00385,376,386,Neutropenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006925,S00385,254,278,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006926,S00385,21,43,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006927,S00385,446,452,Sepsis,Infections and infestations,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0006928,S00385,367,392,Complement activation,Immune system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006929,S00386,637,646,Headache,Nervous system disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0006930,S00386,97,109,Bilirubin increased,Investigations,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0006931,S00386,254,271,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006932,S00386,600,613,Fatigue,General disorders,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006933,S00386,97,104,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006934,S00386,191,206,Fatigue,General disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006935,S00386,685,696,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006936,S00386,204,211,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006937,S00386,501,507,Confusional state,Psychiatric disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006938,S00386,51,78,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006939,S00386,491,494,Pyrexia,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006940,S00386,584,611,Hypogammaglobulinaemia,Immune system disorders,3,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006941,S00386,678,679,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0006942,S00386,246,260,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006943,S00386,190,194,Pyrexia,General disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006944,S00386,486,513,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006945,S00386,112,141,Seizure,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006946,S00386,465,483,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006947,S00386,82,95,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006948,S00386,577,605,Aphasia,Nervous system disorders,2,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0006949,S00386,47,60,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0006950,S00386,599,627,Hypogammaglobulinaemia,Immune system disorders,3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0006951,S00386,523,546,Vomiting,Gastrointestinal disorders,2,N,Y,Dose modification,Unknown,N,0,N,0,N,N,N
AE0006952,S00386,634,647,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006953,S00386,42,65,Headache,Nervous system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006954,S00386,111,120,Headache,Nervous system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006955,S00387,4,20,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0006956,S00387,10,19,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0006957,S00387,523,542,Headache,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006958,S00387,81,93,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0006959,S00387,487,512,Thrombocytopenia,Blood and lymphatic system,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0006960,S00387,396,410,Aspartate aminotransferase increased,Investigations,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006961,S00387,691,706,Bilirubin increased,Investigations,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006962,S00387,425,454,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006963,S00387,247,256,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006964,S00387,98,120,Cytomegalovirus infection,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006965,S00387,385,394,Alanine aminotransferase increased,Investigations,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006966,S00387,150,173,Sepsis,Infections and infestations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0006967,S00387,129,145,Nausea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0006968,S00387,546,558,Seizure,Nervous system disorders,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006969,S00387,376,379,Anaemia,Blood and lymphatic system,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006970,S00387,721,746,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0006971,S00387,71,80,Complement activation,Immune system disorders,1,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0006972,S00387,319,346,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006973,S00387,139,159,Fatigue,General disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006974,S00387,106,119,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006975,S00387,104,122,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0006976,S00387,562,572,Headache,Nervous system disorders,3,N,N,None,Unknown,N,0,N,0,N,N,N
AE0006977,S00387,513,519,Nausea,Gastrointestinal disorders,1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0006978,S00387,613,625,Pyrexia,General disorders,3,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0006979,S00387,286,292,Aphasia,Nervous system disorders,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0006980,S00387,195,199,Hypogammaglobulinaemia,Immune system disorders,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006981,S00387,570,583,Aspartate aminotransferase increased,Investigations,2,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0006982,S00387,461,478,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006983,S00387,122,127,Diarrhoea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0006984,S00387,36,61,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006985,S00387,450,471,Bilirubin increased,Investigations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006986,S00387,583,598,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0006987,S00388,27,42,Alanine aminotransferase increased,Investigations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0006988,S00388,494,508,Confusional state,Psychiatric disorders,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006989,S00388,169,171,Thrombocytopenia,Blood and lymphatic system,2,N,Y,Dose modification,Unknown,N,0,N,0,N,N,N
AE0006990,S00388,671,686,Complement activation,Immune system disorders,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006991,S00388,47,54,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0006992,S00388,613,640,Seizure,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0006993,S00388,576,584,Complement activation,Immune system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006994,S00388,118,126,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006995,S00388,404,414,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0006996,S00388,551,573,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0006997,S00388,131,139,Tachycardia,Cardiac disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0006998,S00388,430,445,Complement activation,Immune system disorders,1,N,N,Drug interrupted,Fatal,N,0,N,0,N,N,N
AE0006999,S00388,151,168,Confusional state,Psychiatric disorders,3,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0007000,S00388,381,391,Sepsis,Infections and infestations,5,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0007001,S00388,606,618,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007002,S00388,588,617,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007003,S00388,542,544,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007004,S00388,330,335,Sepsis,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007005,S00388,48,62,Cytomegalovirus infection,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007006,S00388,437,465,Pyrexia,General disorders,2,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0007007,S00389,284,296,Nausea,Gastrointestinal disorders,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007008,S00389,700,712,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007009,S00389,713,728,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007010,S00389,720,741,Thrombocytopenia,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007011,S00389,660,686,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007012,S00389,165,176,Thrombocytopenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007013,S00389,577,581,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007014,S00389,651,673,Fatigue,General disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007015,S00389,169,177,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007016,S00389,372,380,Neutropenia,Blood and lymphatic system,4,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007017,S00389,171,188,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007018,S00389,578,589,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007019,S00389,407,418,Tremor,Nervous system disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007020,S00389,547,568,Neutropenia,Blood and lymphatic system,1,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0007021,S00389,682,698,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0007022,S00390,489,515,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007023,S00390,630,637,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007024,S00390,220,225,Vomiting,Gastrointestinal disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0007025,S00390,394,408,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007026,S00390,320,323,Cytomegalovirus infection,Infections and infestations,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007027,S00390,361,366,Aphasia,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007028,S00390,591,617,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007029,S00390,580,595,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007030,S00390,183,188,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007031,S00390,10,11,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007032,S00390,328,351,Headache,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007033,S00390,376,392,Sepsis,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007034,S00390,587,601,Diarrhoea,Gastrointestinal disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007035,S00390,336,355,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0007036,S00390,263,276,Thrombocytopenia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007037,S00390,227,237,Seizure,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007038,S00390,406,422,Complement activation,Immune system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0007039,S00390,72,88,Nausea,Gastrointestinal disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007040,S00390,15,31,Hypotension,Vascular disorders,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007041,S00390,361,383,Neutropenia,Blood and lymphatic system,5,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007042,S00390,118,135,Diarrhoea,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007043,S00390,231,260,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007044,S00390,347,371,Thrombocytopenia,Blood and lymphatic system,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007045,S00390,17,27,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007046,S00391,7,21,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0007047,S00391,8,12,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0007048,S00391,595,598,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007049,S00391,550,564,Cytomegalovirus infection,Infections and infestations,2,N,N,None,Fatal,N,0,N,0,N,N,N
AE0007050,S00391,656,667,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007051,S00391,428,455,Diarrhoea,Gastrointestinal disorders,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0007052,S00391,342,345,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007053,S00391,560,561,Neutropenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007054,S00391,15,22,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,None,Recovering,N,0,N,0,N,Y,Y
AE0007055,S00391,611,623,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007056,S00391,539,559,Confusional state,Psychiatric disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007057,S00391,130,133,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0007058,S00391,199,200,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,Dose modification,Recovered,N,0,N,0,N,Y,Y
AE0007059,S00391,604,633,Mucosal inflammation,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007060,S00391,307,336,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007061,S00391,716,743,Anaemia,Blood and lymphatic system,3,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0007062,S00391,317,335,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007063,S00391,164,193,Aphasia,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007064,S00391,569,591,Fatigue,General disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0007065,S00391,88,103,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007066,S00391,522,542,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007067,S00391,530,550,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007068,S00391,148,175,Hypogammaglobulinaemia,Immune system disorders,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007069,S00392,182,202,Hypotension,Vascular disorders,4,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007070,S00392,497,503,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007071,S00392,179,184,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007072,S00392,434,446,Fatigue,General disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007073,S00392,316,319,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007074,S00392,244,249,Bilirubin increased,Investigations,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007075,S00392,204,223,Sepsis,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007076,S00392,291,303,Seizure,Nervous system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007077,S00392,706,732,Infusion related reaction,"Injury, poisoning, procedural",4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007078,S00392,419,445,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007079,S00392,76,101,Hypogammaglobulinaemia,Immune system disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007080,S00392,144,150,Fatigue,General disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007081,S00392,152,173,Aphasia,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007082,S00393,179,196,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007083,S00393,70,89,Diarrhoea,Gastrointestinal disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007084,S00393,437,460,Fatigue,General disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007085,S00393,606,634,Alanine aminotransferase increased,Investigations,4,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007086,S00393,128,138,Tachycardia,Cardiac disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0007087,S00393,172,182,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007088,S00394,7,21,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0007089,S00394,660,682,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007090,S00394,589,618,Tremor,Nervous system disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0007091,S00394,429,443,Fatigue,General disorders,3,Y,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007092,S00394,26,42,Tachycardia,Cardiac disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007093,S00394,325,352,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,Hospitalization,Not recovered,N,0,N,0,N,Y,Y
AE0007094,S00394,201,230,Fatigue,General disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0007095,S00394,563,589,Neutropenia,Blood and lymphatic system,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007096,S00394,267,294,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007097,S00394,322,332,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Concomitant medication,Recovering,N,0,N,0,N,Y,Y
AE0007098,S00394,184,208,Pyrexia,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007099,S00394,194,208,Hypotension,Vascular disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007100,S00394,57,76,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,Y,Y
AE0007101,S00394,627,649,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007102,S00394,644,654,Confusional state,Psychiatric disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007103,S00394,425,431,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007104,S00394,526,545,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007105,S00394,159,166,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007106,S00394,271,273,Seizure,Nervous system disorders,5,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007107,S00394,343,346,Pyrexia,General disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007108,S00394,693,695,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0007109,S00394,722,742,Neutropenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007110,S00395,430,447,Sepsis,Infections and infestations,2,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0007111,S00395,467,490,Aphasia,Nervous system disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007112,S00395,619,646,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007113,S00395,205,221,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007114,S00395,300,322,Infusion related reaction,"Injury, poisoning, procedural",3,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0007115,S00395,396,418,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007116,S00395,642,670,Headache,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007117,S00395,584,587,Vomiting,Gastrointestinal disorders,1,N,Y,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0007118,S00395,662,670,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007119,S00395,33,45,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007120,S00395,65,81,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007121,S00395,34,57,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0007122,S00395,375,391,Sepsis,Infections and infestations,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007123,S00396,39,46,Hepatocellular injury,Hepatobiliary disorders,4,Y,Y,Tocilizumab,Recovered with sequelae,Y,0,N,0,Y,N,Y
AE0007124,S00396,391,406,Bilirubin increased,Investigations,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007125,S00396,230,233,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0007126,S00396,728,745,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007127,S00396,508,522,Bilirubin increased,Investigations,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007128,S00396,464,475,Neutropenia,Blood and lymphatic system,2,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0007129,S00396,126,129,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007130,S00397,3,9,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0007131,S00397,165,174,Anaemia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007132,S00397,266,286,Pyrexia,General disorders,1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0007133,S00397,501,527,Fatigue,General disorders,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007134,S00397,329,335,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0007135,S00397,626,634,Mucosal inflammation,Gastrointestinal disorders,2,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0007136,S00397,696,713,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007137,S00397,222,250,Pyrexia,General disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007138,S00397,337,364,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007139,S00397,562,567,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007140,S00397,241,252,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007141,S00397,585,610,Sepsis,Infections and infestations,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0007142,S00397,346,350,Confusional state,Psychiatric disorders,4,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0007143,S00397,203,217,Fatigue,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007144,S00397,593,605,Bilirubin increased,Investigations,3,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0007145,S00397,173,194,Sepsis,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007146,S00397,39,55,Seizure,Nervous system disorders,1,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0007147,S00397,634,659,Alanine aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007148,S00397,326,335,Aspartate aminotransferase increased,Investigations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007149,S00397,425,442,Sepsis,Infections and infestations,3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0007150,S00397,137,154,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007151,S00397,651,665,Tremor,Nervous system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007152,S00397,220,236,Vomiting,Gastrointestinal disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0007153,S00397,203,214,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007154,S00397,311,339,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0007155,S00398,464,468,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007156,S00398,650,651,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007157,S00398,406,424,Nausea,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007158,S00398,494,514,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007159,S00398,512,540,Cytomegalovirus infection,Infections and infestations,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007160,S00398,637,642,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0007161,S00398,254,271,Bilirubin increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007162,S00398,705,708,Tremor,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007163,S00398,295,315,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0007164,S00398,457,466,Diarrhoea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007165,S00398,251,274,Hypotension,Vascular disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0007166,S00398,62,70,Bilirubin increased,Investigations,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0007167,S00398,574,600,Fatigue,General disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007168,S00398,648,676,Complement activation,Immune system disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007169,S00398,598,610,Seizure,Nervous system disorders,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007170,S00398,141,168,Pyrexia,General disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007171,S00398,559,584,Complement activation,Immune system disorders,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007172,S00398,185,193,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007173,S00398,350,374,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007174,S00398,549,552,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007175,S00398,194,206,Aspartate aminotransferase increased,Investigations,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0007176,S00398,238,266,Pyrexia,General disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007177,S00398,627,651,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0007178,S00398,289,315,Hypogammaglobulinaemia,Immune system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007179,S00398,464,490,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007180,S00400,232,246,Complement activation,Immune system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007181,S00400,52,70,Anaemia,Blood and lymphatic system,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0007182,S00400,691,717,Vomiting,Gastrointestinal disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007183,S00400,325,329,Anaemia,Blood and lymphatic system,1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0007184,S00400,511,531,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007185,S00400,507,529,Seizure,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007186,S00400,168,177,Pyrexia,General disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007187,S00400,689,697,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007188,S00401,75,76,Alanine aminotransferase increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007189,S00401,688,691,Pyrexia,General disorders,4,N,Y,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0007190,S00401,485,502,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007191,S00401,303,322,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007192,S00401,531,560,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007193,S00401,118,134,Aphasia,Nervous system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007194,S00401,49,60,Hypotension,Vascular disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007195,S00401,431,456,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007196,S00401,232,251,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007197,S00401,445,458,Complement activation,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007198,S00401,188,196,Tachycardia,Cardiac disorders,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0007199,S00401,351,362,Seizure,Nervous system disorders,5,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007200,S00401,592,611,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007201,S00401,463,467,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0007202,S00402,7,19,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0007203,S00402,333,355,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007204,S00402,583,594,Bilirubin increased,Investigations,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007205,S00402,429,435,Hypoxia,"Respiratory, thoracic, mediastinal",3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007206,S00402,473,475,Confusional state,Psychiatric disorders,3,Y,Y,None,Recovering,N,0,N,0,N,N,N
AE0007207,S00402,328,342,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007208,S00402,561,574,Sepsis,Infections and infestations,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007209,S00402,244,255,Seizure,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007210,S00402,267,272,Pyrexia,General disorders,3,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0007211,S00402,443,471,Anaemia,Blood and lymphatic system,5,N,Y,Dose modification,Unknown,N,0,N,0,N,N,N
AE0007212,S00402,517,530,Anaemia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007213,S00402,345,363,Hypogammaglobulinaemia,Immune system disorders,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007214,S00402,668,678,Fatigue,General disorders,2,N,Y,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0007215,S00402,443,469,Sepsis,Infections and infestations,5,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007216,S00402,374,382,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007217,S00402,150,164,Complement activation,Immune system disorders,1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0007218,S00402,546,570,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0007219,S00402,535,542,Aphasia,Nervous system disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007220,S00402,105,111,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,None,Not recovered,N,0,N,0,N,Y,Y
AE0007221,S00402,355,369,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007222,S00402,599,623,Cytomegalovirus infection,Infections and infestations,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007223,S00402,409,416,Hypotension,Vascular disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007224,S00402,499,504,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007225,S00402,673,695,Thrombocytopenia,Blood and lymphatic system,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007226,S00402,152,163,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007227,S00402,500,517,Tachycardia,Cardiac disorders,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007228,S00402,442,447,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007229,S00402,101,104,Seizure,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007230,S00402,333,338,Alanine aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007231,S00402,454,483,Neutropenia,Blood and lymphatic system,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007232,S00403,5,18,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0007233,S00403,82,85,Vomiting,Gastrointestinal disorders,5,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007234,S00403,458,470,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0007235,S00403,694,706,Thrombotic microangiopathy,Blood and lymphatic system,3,Y,N,None,Recovered,N,0,N,0,N,Y,Y
AE0007236,S00403,520,534,Tachycardia,Cardiac disorders,2,N,N,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0007237,S00403,407,411,Seizure,Nervous system disorders,4,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007238,S00403,254,256,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007239,S00403,323,327,Mucosal inflammation,Gastrointestinal disorders,3,Y,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0007240,S00403,259,264,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007241,S00403,110,113,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007242,S00403,396,421,Pyrexia,General disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007243,S00403,214,236,Neutropenia,Blood and lymphatic system,4,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007244,S00403,311,326,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007245,S00403,138,164,Fatigue,General disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007246,S00403,248,250,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,Drug interrupted,Recovered,N,0,N,0,N,Y,Y
AE0007247,S00403,452,458,Seizure,Nervous system disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007248,S00403,23,30,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007249,S00403,586,591,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007250,S00403,362,367,Nausea,Gastrointestinal disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007251,S00403,367,374,Headache,Nervous system disorders,5,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0007252,S00403,208,227,Tachycardia,Cardiac disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007253,S00403,27,46,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007254,S00403,420,448,Aspartate aminotransferase increased,Investigations,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007255,S00403,666,691,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007256,S00405,568,588,Hypotension,Vascular disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0007257,S00405,370,390,Confusional state,Psychiatric disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007258,S00405,54,64,Neutropenia,Blood and lymphatic system,4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007259,S00405,623,630,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007260,S00405,136,141,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007261,S00405,48,61,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007262,S00405,456,462,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0007263,S00405,548,567,Nausea,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007264,S00405,422,431,Sepsis,Infections and infestations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007265,S00405,293,314,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0007266,S00405,184,200,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007267,S00405,489,503,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0007268,S00405,313,329,Anaemia,Blood and lymphatic system,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007269,S00405,409,422,Bilirubin increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007270,S00405,376,390,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007271,S00405,109,111,Neutropenia,Blood and lymphatic system,3,N,N,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0007272,S00406,1,12,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0007273,S00406,648,661,Aphasia,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007274,S00406,405,430,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007275,S00406,141,156,Neutropenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007276,S00406,698,702,Confusional state,Psychiatric disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007277,S00406,20,42,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007278,S00406,192,196,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007279,S00406,508,531,Fatigue,General disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007280,S00406,639,644,Tachycardia,Cardiac disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007281,S00406,637,654,Hypotension,Vascular disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007282,S00406,416,433,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007283,S00406,78,79,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007284,S00406,532,550,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007285,S00406,407,435,Nausea,Gastrointestinal disorders,3,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007286,S00406,255,282,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007287,S00406,204,206,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007288,S00406,369,372,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007289,S00406,177,178,Sepsis,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007290,S00406,360,382,Thrombocytopenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007291,S00406,452,472,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007292,S00406,352,377,Hypogammaglobulinaemia,Immune system disorders,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007293,S00406,165,194,Anaemia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007294,S00406,699,705,Aphasia,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007295,S00406,523,532,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007296,S00406,637,638,Seizure,Nervous system disorders,3,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0007297,S00406,209,229,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007298,S00406,125,148,Complement activation,Immune system disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007299,S00406,532,552,Headache,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007300,S00407,12,36,Thrombocytopenia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007301,S00407,631,654,Aspartate aminotransferase increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007302,S00407,254,268,Bilirubin increased,Investigations,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0007303,S00407,98,102,Mucosal inflammation,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007304,S00407,568,569,Fatigue,General disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007305,S00407,111,132,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007306,S00407,543,564,Diarrhoea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0007307,S00407,363,383,Complement activation,Immune system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007308,S00407,8,34,Aphasia,Nervous system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007309,S00407,558,572,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007310,S00407,433,454,Alanine aminotransferase increased,Investigations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007311,S00407,474,499,Sepsis,Infections and infestations,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007312,S00407,667,672,Hypotension,Vascular disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007313,S00408,265,286,Aphasia,Nervous system disorders,5,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0007314,S00408,481,492,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007315,S00408,599,624,Diarrhoea,Gastrointestinal disorders,1,N,N,Dose modification,Unknown,N,0,N,0,N,N,N
AE0007316,S00408,351,367,Anaemia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007317,S00408,81,96,Neutropenia,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007318,S00408,87,92,Pyrexia,General disorders,1,N,N,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0007319,S00408,555,573,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007320,S00408,259,263,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0007321,S00408,36,48,Pyrexia,General disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007322,S00408,64,91,Nausea,Gastrointestinal disorders,3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0007323,S00408,687,704,Alanine aminotransferase increased,Investigations,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007324,S00408,675,692,Anaemia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007325,S00408,218,223,Anaemia,Blood and lymphatic system,1,N,N,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0007326,S00408,249,267,Complement activation,Immune system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007327,S00408,175,194,Hypogammaglobulinaemia,Immune system disorders,3,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0007328,S00408,302,327,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007329,S00408,105,133,Hypotension,Vascular disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007330,S00408,122,124,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007331,S00408,83,91,Tremor,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0007332,S00408,520,522,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007333,S00408,287,309,Aphasia,Nervous system disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007334,S00408,60,84,Tremor,Nervous system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007335,S00408,150,177,Cough,"Respiratory, thoracic, mediastinal",2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0007336,S00408,311,337,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007337,S00408,442,465,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007338,S00408,288,302,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007339,S00408,633,642,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007340,S00408,67,91,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007341,S00408,154,171,Tremor,Nervous system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007342,S00408,606,626,Complement activation,Immune system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007343,S00408,676,688,Sepsis,Infections and infestations,2,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0007344,S00408,625,628,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007345,S00408,428,457,Confusional state,Psychiatric disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007346,S00408,698,703,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007347,S00408,457,472,Pyrexia,General disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007348,S00408,229,235,Neutropenia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007349,S00410,625,630,Thrombocytopenia,Blood and lymphatic system,2,N,N,Hospitalization,Fatal,N,0,N,0,N,N,N
AE0007350,S00410,660,678,Tachycardia,Cardiac disorders,3,Y,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007351,S00410,245,270,Alanine aminotransferase increased,Investigations,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0007352,S00410,343,365,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007353,S00410,341,350,Bilirubin increased,Investigations,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007354,S00410,725,729,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007355,S00410,202,227,Diarrhoea,Gastrointestinal disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007356,S00410,184,196,Bilirubin increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007357,S00410,493,517,Anaemia,Blood and lymphatic system,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007358,S00410,652,657,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007359,S00410,632,634,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007360,S00410,255,261,Mucosal inflammation,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007361,S00410,376,405,Complement activation,Immune system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007362,S00410,722,738,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007363,S00410,545,566,Seizure,Nervous system disorders,4,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0007364,S00410,448,462,Aphasia,Nervous system disorders,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007365,S00410,221,246,Neutropenia,Blood and lymphatic system,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007366,S00410,238,264,Complement activation,Immune system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007367,S00410,137,143,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007368,S00410,699,707,Bilirubin increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007369,S00410,554,566,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007370,S00410,258,283,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0007371,S00410,570,592,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007372,S00411,643,662,Confusional state,Psychiatric disorders,3,Y,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007373,S00411,706,714,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,Y,Y
AE0007374,S00411,317,341,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007375,S00411,100,105,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007376,S00411,292,310,Anaemia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007377,S00411,43,51,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007378,S00411,577,583,Vomiting,Gastrointestinal disorders,5,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0007379,S00411,75,83,Neutropenia,Blood and lymphatic system,1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0007380,S00411,612,633,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007381,S00411,439,465,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007382,S00411,302,329,Bilirubin increased,Investigations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007383,S00411,329,343,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007384,S00411,494,521,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0007385,S00411,603,625,Aspartate aminotransferase increased,Investigations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007386,S00411,83,109,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007387,S00411,331,345,Fatigue,General disorders,5,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007388,S00411,47,55,Hypogammaglobulinaemia,Immune system disorders,4,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007389,S00411,443,446,Pyrexia,General disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007390,S00411,658,672,Aspartate aminotransferase increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007391,S00411,318,339,Anaemia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007392,S00411,224,242,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007393,S00411,348,374,Aphasia,Nervous system disorders,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0007394,S00411,209,227,Thrombocytopenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007395,S00411,163,186,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007396,S00411,481,490,Aphasia,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007397,S00411,473,479,Sepsis,Infections and infestations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007398,S00411,152,160,Seizure,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007399,S00411,241,265,Aphasia,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007400,S00411,127,148,Vomiting,Gastrointestinal disorders,1,N,N,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0007401,S00411,711,721,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007402,S00411,723,732,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007403,S00412,5,17,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0007404,S00412,472,494,Anaemia,Blood and lymphatic system,3,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007405,S00412,479,508,Tremor,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007406,S00412,434,460,Confusional state,Psychiatric disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007407,S00412,353,355,Headache,Nervous system disorders,3,Y,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007408,S00412,686,697,Anaemia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007409,S00412,580,593,Complement activation,Immune system disorders,2,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0007410,S00412,567,571,Neutropenia,Blood and lymphatic system,4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007411,S00412,439,452,Confusional state,Psychiatric disorders,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007412,S00412,674,690,Cytomegalovirus infection,Infections and infestations,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007413,S00412,507,535,Bilirubin increased,Investigations,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007414,S00412,423,450,Diarrhoea,Gastrointestinal disorders,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007415,S00412,226,249,Aphasia,Nervous system disorders,3,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007416,S00412,17,45,Neutropenia,Blood and lymphatic system,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007417,S00412,239,253,Mucosal inflammation,Gastrointestinal disorders,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007418,S00412,314,332,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007419,S00412,144,146,Anaemia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007420,S00412,73,97,Cytomegalovirus infection,Infections and infestations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007421,S00412,510,523,Aphasia,Nervous system disorders,4,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0007422,S00413,436,465,Cytomegalovirus infection,Infections and infestations,5,Y,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007423,S00413,531,552,Headache,Nervous system disorders,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007424,S00413,174,197,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007425,S00413,508,517,Cough,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007426,S00413,274,288,Aspartate aminotransferase increased,Investigations,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007427,S00413,693,696,Vomiting,Gastrointestinal disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007428,S00413,36,47,Hypoxia,"Respiratory, thoracic, mediastinal",5,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007429,S00413,636,663,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0007430,S00413,291,302,Aspartate aminotransferase increased,Investigations,2,N,N,Drug interrupted,Fatal,N,0,N,0,N,N,N
AE0007431,S00413,610,627,Bilirubin increased,Investigations,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007432,S00413,228,257,Aspartate aminotransferase increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007433,S00414,3,16,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0007434,S00414,624,649,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007435,S00414,364,381,Diarrhoea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0007436,S00414,196,218,Hypoxia,"Respiratory, thoracic, mediastinal",3,Y,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007437,S00414,679,699,Bilirubin increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007438,S00414,503,519,Sepsis,Infections and infestations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007439,S00414,579,608,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007440,S00414,639,642,Headache,Nervous system disorders,1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0007441,S00414,112,132,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0007442,S00414,642,645,Seizure,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007443,S00414,345,349,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0007444,S00414,298,306,Anaemia,Blood and lymphatic system,3,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0007445,S00414,3,15,Nausea,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007446,S00414,40,61,Sepsis,Infections and infestations,2,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0007447,S00414,40,66,Cytomegalovirus infection,Infections and infestations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007448,S00414,9,16,Complement activation,Immune system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007449,S00414,158,163,Aspartate aminotransferase increased,Investigations,3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0007450,S00414,84,104,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007451,S00414,552,557,Alanine aminotransferase increased,Investigations,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007452,S00414,339,349,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007453,S00414,190,200,Alanine aminotransferase increased,Investigations,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0007454,S00414,693,701,Nausea,Gastrointestinal disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007455,S00414,316,341,Seizure,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0007456,S00414,79,80,Aphasia,Nervous system disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0007457,S00414,672,690,Neutropenia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007458,S00414,11,26,Seizure,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007459,S00414,410,421,Thrombocytopenia,Blood and lymphatic system,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007460,S00416,294,314,Headache,Nervous system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007461,S00416,302,314,Confusional state,Psychiatric disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007462,S00416,202,206,Fatigue,General disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0007463,S00416,281,304,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007464,S00416,34,45,Diarrhoea,Gastrointestinal disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007465,S00416,469,477,Complement activation,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007466,S00416,167,185,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007467,S00416,604,607,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0007468,S00416,151,177,Bilirubin increased,Investigations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007469,S00416,260,277,Aphasia,Nervous system disorders,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007470,S00416,164,179,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007471,S00416,583,586,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007472,S00416,161,182,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007473,S00416,225,246,Alanine aminotransferase increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007474,S00416,406,407,Fatigue,General disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007475,S00416,308,322,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007476,S00416,487,504,Hypogammaglobulinaemia,Immune system disorders,4,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007477,S00416,555,568,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007478,S00416,466,495,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0007479,S00416,314,342,Complement activation,Immune system disorders,2,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0007480,S00416,50,55,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,Concomitant medication,Fatal,N,0,N,0,N,Y,Y
AE0007481,S00416,636,644,Hypogammaglobulinaemia,Immune system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007482,S00417,350,365,Fatigue,General disorders,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0007483,S00417,566,584,Tachycardia,Cardiac disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007484,S00417,351,371,Alanine aminotransferase increased,Investigations,3,Y,Y,None,Unknown,N,0,N,0,N,N,N
AE0007485,S00417,173,178,Tachycardia,Cardiac disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0007486,S00417,628,638,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007487,S00417,84,110,Seizure,Nervous system disorders,5,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007488,S00417,274,276,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0007489,S00417,309,316,Cytomegalovirus infection,Infections and infestations,5,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007490,S00417,548,566,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0007491,S00417,185,204,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007492,S00417,188,209,Headache,Nervous system disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007493,S00417,212,225,Vomiting,Gastrointestinal disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007494,S00418,5,8,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0007495,S00418,60,85,Pyrexia,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007496,S00418,383,408,Complement activation,Immune system disorders,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007497,S00418,666,676,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007498,S00418,691,706,Tremor,Nervous system disorders,2,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0007499,S00418,713,716,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007500,S00418,25,40,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0007501,S00418,330,359,Seizure,Nervous system disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0007502,S00418,31,39,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007503,S00418,688,696,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007504,S00418,671,691,Pyrexia,General disorders,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0007505,S00418,530,559,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007506,S00418,40,69,Bilirubin increased,Investigations,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007507,S00418,318,334,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007508,S00418,215,219,Seizure,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007509,S00418,638,647,Sepsis,Infections and infestations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007510,S00418,339,354,Diarrhoea,Gastrointestinal disorders,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007511,S00418,191,202,Fatigue,General disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007512,S00418,637,639,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007513,S00418,304,310,Alanine aminotransferase increased,Investigations,5,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007514,S00418,223,234,Fatigue,General disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007515,S00418,87,112,Cough,"Respiratory, thoracic, mediastinal",2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007516,S00418,326,333,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007517,S00418,595,603,Aspartate aminotransferase increased,Investigations,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007518,S00418,103,125,Confusional state,Psychiatric disorders,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007519,S00418,618,638,Thrombocytopenia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007520,S00418,673,693,Confusional state,Psychiatric disorders,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0007521,S00418,99,109,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007522,S00418,635,643,Cytomegalovirus infection,Infections and infestations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007523,S00418,206,220,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007524,S00418,361,381,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007525,S00418,129,139,Hypogammaglobulinaemia,Immune system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007526,S00419,558,562,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007527,S00419,325,341,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007528,S00419,712,737,Hypogammaglobulinaemia,Immune system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007529,S00419,41,48,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007530,S00419,705,717,Pyrexia,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007531,S00419,647,676,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0007532,S00419,159,175,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007533,S00419,46,54,Hypogammaglobulinaemia,Immune system disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007534,S00419,453,462,Tachycardia,Cardiac disorders,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0007535,S00419,599,607,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007536,S00419,334,340,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0007537,S00419,274,284,Anaemia,Blood and lymphatic system,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007538,S00419,296,302,Sepsis,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007539,S00419,9,34,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0007540,S00420,5,25,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0007541,S00420,9,25,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,2,N,Y,Corticosteroids,Recovered,N,0,Y,2,N,N,Y
AE0007542,S00420,557,565,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0007543,S00420,390,392,Fatigue,General disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007544,S00420,222,233,Aphasia,Nervous system disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007545,S00420,326,353,Anaemia,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007546,S00420,653,679,Seizure,Nervous system disorders,3,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007547,S00420,73,95,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007548,S00420,13,23,Tachycardia,Cardiac disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007549,S00420,656,669,Headache,Nervous system disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007550,S00420,202,225,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007551,S00420,531,541,Pyrexia,General disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007552,S00420,324,344,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,Y,Y
AE0007553,S00420,643,649,Complement activation,Immune system disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0007554,S00420,663,684,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007555,S00420,408,417,Aphasia,Nervous system disorders,5,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0007556,S00420,10,37,Cytomegalovirus infection,Infections and infestations,4,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0007557,S00420,634,659,Nausea,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007558,S00420,608,622,Hypotension,Vascular disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007559,S00420,380,409,Vomiting,Gastrointestinal disorders,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007560,S00420,378,390,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,Y,Y
AE0007561,S00420,195,212,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007562,S00420,313,322,Anaemia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007563,S00420,270,271,Mucosal inflammation,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007564,S00420,85,111,Nausea,Gastrointestinal disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007565,S00420,498,518,Aphasia,Nervous system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007566,S00420,133,134,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007567,S00420,501,519,Aphasia,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007568,S00420,337,345,Aphasia,Nervous system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007569,S00420,422,446,Thrombocytopenia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007570,S00421,4,22,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0007571,S00421,5,24,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0007572,S00421,705,711,Tremor,Nervous system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007573,S00421,706,729,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007574,S00421,368,391,Cytomegalovirus infection,Infections and infestations,3,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0007575,S00421,195,217,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007576,S00421,653,666,Seizure,Nervous system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007577,S00421,262,284,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007578,S00421,279,296,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0007579,S00421,54,76,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007580,S00421,660,670,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007581,S00421,110,117,Sepsis,Infections and infestations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007582,S00421,375,382,Aphasia,Nervous system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007583,S00421,161,176,Neutropenia,Blood and lymphatic system,5,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0007584,S00421,685,700,Neutropenia,Blood and lymphatic system,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007585,S00421,408,416,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007586,S00421,58,76,Seizure,Nervous system disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007587,S00421,547,554,Neutropenia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007588,S00421,662,669,Hypotension,Vascular disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007589,S00421,524,541,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007590,S00421,368,381,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007591,S00422,266,291,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007592,S00422,672,695,Aphasia,Nervous system disorders,4,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007593,S00422,563,578,Alanine aminotransferase increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007594,S00422,75,82,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007595,S00422,462,471,Confusional state,Psychiatric disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007596,S00422,31,58,Bilirubin increased,Investigations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007597,S00422,68,82,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007598,S00422,582,603,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007599,S00422,312,316,Tachycardia,Cardiac disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007600,S00422,637,649,Cytomegalovirus infection,Infections and infestations,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007601,S00422,407,423,Complement activation,Immune system disorders,2,N,N,None,Fatal,N,0,N,0,N,N,N
AE0007602,S00424,620,637,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007603,S00424,411,428,Hypotension,Vascular disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0007604,S00424,389,418,Hypogammaglobulinaemia,Immune system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007605,S00424,702,723,Confusional state,Psychiatric disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007606,S00424,347,368,Tremor,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007607,S00424,29,45,Sepsis,Infections and infestations,5,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007608,S00424,282,310,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007609,S00424,490,502,Aphasia,Nervous system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007610,S00424,608,614,Nausea,Gastrointestinal disorders,1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0007611,S00424,718,722,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007612,S00424,606,627,Pyrexia,General disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007613,S00425,158,164,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007614,S00425,617,639,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007615,S00425,166,189,Tremor,Nervous system disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0007616,S00425,497,516,Hypogammaglobulinaemia,Immune system disorders,4,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007617,S00425,719,728,Pyrexia,General disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0007618,S00425,128,139,Aspartate aminotransferase increased,Investigations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007619,S00425,276,299,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007620,S00425,122,133,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007621,S00426,5,17,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0007622,S00426,3,12,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,2,N,Y,Corticosteroids,Recovered,N,0,Y,2,N,N,Y
AE0007623,S00426,285,300,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007624,S00426,351,356,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007625,S00426,50,77,Aphasia,Nervous system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007626,S00426,339,354,Cytomegalovirus infection,Infections and infestations,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007627,S00426,202,227,Bilirubin increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007628,S00426,648,672,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007629,S00426,683,706,Tachycardia,Cardiac disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007630,S00426,552,581,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0007631,S00426,618,644,Cytomegalovirus infection,Infections and infestations,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007632,S00426,614,622,Sepsis,Infections and infestations,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007633,S00426,498,526,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007634,S00426,17,18,Complement activation,Immune system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007635,S00426,402,417,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007636,S00426,479,480,Mucosal inflammation,Gastrointestinal disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007637,S00426,133,156,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007638,S00426,489,501,Hypotension,Vascular disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007639,S00426,334,342,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007640,S00426,110,130,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,Y,Y
AE0007641,S00426,636,657,Vomiting,Gastrointestinal disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007642,S00426,539,559,Aphasia,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007643,S00427,222,230,Mucosal inflammation,Gastrointestinal disorders,3,Y,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007644,S00427,196,200,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007645,S00427,413,437,Aphasia,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007646,S00427,193,214,Nausea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007647,S00427,379,400,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007648,S00427,396,407,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007649,S00427,450,464,Tremor,Nervous system disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007650,S00427,296,302,Confusional state,Psychiatric disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007651,S00427,311,313,Neutropenia,Blood and lymphatic system,5,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007652,S00427,292,321,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007653,S00427,82,107,Headache,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007654,S00427,547,548,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Not recovered,N,0,N,0,N,Y,Y
AE0007655,S00427,236,237,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007656,S00427,360,376,Tachycardia,Cardiac disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0007657,S00428,4,21,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0007658,S00428,422,446,Hypotension,Vascular disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007659,S00428,270,289,Confusional state,Psychiatric disorders,4,N,N,None,Unknown,N,0,N,0,N,N,N
AE0007660,S00428,259,283,Neutropenia,Blood and lymphatic system,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007661,S00428,380,386,Alanine aminotransferase increased,Investigations,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007662,S00428,399,411,Complement activation,Immune system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007663,S00428,284,288,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007664,S00428,246,263,Tremor,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007665,S00428,86,103,Anaemia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007666,S00428,92,110,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007667,S00428,520,533,Nausea,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007668,S00428,697,721,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0007669,S00428,95,114,Cough,"Respiratory, thoracic, mediastinal",2,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0007670,S00428,349,356,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007671,S00428,36,58,Bilirubin increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007672,S00428,366,380,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007673,S00428,544,559,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007674,S00428,630,641,Neutropenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007675,S00428,120,144,Complement activation,Immune system disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007676,S00428,100,124,Pyrexia,General disorders,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007677,S00428,390,397,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007678,S00428,64,89,Sepsis,Infections and infestations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007679,S00428,503,513,Bilirubin increased,Investigations,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007680,S00428,95,110,Nausea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0007681,S00428,560,579,Sepsis,Infections and infestations,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007682,S00428,512,524,Headache,Nervous system disorders,1,N,N,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0007683,S00428,11,33,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007684,S00428,600,617,Aphasia,Nervous system disorders,3,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007685,S00428,97,102,Neutropenia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007686,S00428,61,74,Seizure,Nervous system disorders,3,N,Y,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0007687,S00428,281,301,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007688,S00428,445,447,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0007689,S00428,669,673,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007690,S00428,197,207,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0007691,S00429,702,728,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007692,S00429,557,583,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007693,S00429,374,375,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007694,S00429,46,48,Alanine aminotransferase increased,Investigations,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007695,S00429,37,64,Seizure,Nervous system disorders,1,N,N,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0007696,S00429,2,10,Tachycardia,Cardiac disorders,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007697,S00429,309,320,Confusional state,Psychiatric disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0007698,S00429,184,192,Aspartate aminotransferase increased,Investigations,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007699,S00429,708,712,Neutropenia,Blood and lymphatic system,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007700,S00429,342,348,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0007701,S00430,2,16,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0007702,S00430,235,260,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Unknown,N,0,N,0,N,Y,Y
AE0007703,S00430,709,713,Aphasia,Nervous system disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0007704,S00430,690,699,Aspartate aminotransferase increased,Investigations,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007705,S00430,6,17,Pyrexia,General disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007706,S00430,529,535,Cytomegalovirus infection,Infections and infestations,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007707,S00430,503,504,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007708,S00430,297,319,Tremor,Nervous system disorders,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0007709,S00430,372,378,Aphasia,Nervous system disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007710,S00430,290,305,Bilirubin increased,Investigations,1,N,N,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0007711,S00430,146,159,Aspartate aminotransferase increased,Investigations,3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0007712,S00430,245,260,Hypoxia,"Respiratory, thoracic, mediastinal",5,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0007713,S00430,29,41,Complement activation,Immune system disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007714,S00430,136,165,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007715,S00430,324,336,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007716,S00430,206,213,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007717,S00430,239,251,Pyrexia,General disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0007718,S00430,714,716,Bilirubin increased,Investigations,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0007719,S00430,15,22,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007720,S00430,104,117,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007721,S00430,651,659,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007722,S00430,411,438,Neutropenia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007723,S00431,8,21,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0007724,S00431,24,32,Mucosal inflammation,Gastrointestinal disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007725,S00431,408,434,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007726,S00431,243,246,Headache,Nervous system disorders,1,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0007727,S00431,149,169,Complement activation,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007728,S00431,506,520,Bilirubin increased,Investigations,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007729,S00431,432,434,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007730,S00431,285,289,Complement activation,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007731,S00431,136,157,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007732,S00431,431,451,Nausea,Gastrointestinal disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0007733,S00431,12,34,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0007734,S00431,405,418,Seizure,Nervous system disorders,3,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0007735,S00431,416,425,Complement activation,Immune system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007736,S00431,415,436,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Recovering,N,0,N,0,N,Y,Y
AE0007737,S00431,239,258,Pyrexia,General disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007738,S00431,560,588,Tachycardia,Cardiac disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007739,S00431,485,496,Headache,Nervous system disorders,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007740,S00431,503,524,Sepsis,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007741,S00431,456,462,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007742,S00431,214,222,Fatigue,General disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007743,S00431,634,645,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007744,S00431,56,58,Sepsis,Infections and infestations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007745,S00431,659,676,Cytomegalovirus infection,Infections and infestations,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007746,S00431,310,335,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007747,S00431,619,637,Anaemia,Blood and lymphatic system,2,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0007748,S00431,320,323,Pyrexia,General disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007749,S00431,321,345,Vomiting,Gastrointestinal disorders,1,N,Y,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0007750,S00431,75,102,Vomiting,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007751,S00432,7,13,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0007752,S00432,615,643,Mucosal inflammation,Gastrointestinal disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007753,S00432,483,486,Pyrexia,General disorders,4,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007754,S00432,578,598,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0007755,S00432,348,363,Thrombocytopenia,Blood and lymphatic system,3,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0007756,S00432,678,695,Aspartate aminotransferase increased,Investigations,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007757,S00432,458,477,Complement activation,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007758,S00432,262,286,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007759,S00432,143,152,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007760,S00432,125,151,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007761,S00432,485,514,Anaemia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007762,S00432,159,162,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007763,S00432,469,496,Pyrexia,General disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007764,S00432,627,640,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007765,S00432,143,148,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007766,S00432,692,693,Pyrexia,General disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007767,S00432,515,518,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Not recovered,N,0,N,0,N,Y,Y
AE0007768,S00432,660,678,Complement activation,Immune system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007769,S00432,637,640,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,None,Recovering,N,0,N,0,N,Y,Y
AE0007770,S00432,686,696,Sepsis,Infections and infestations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007771,S00432,252,255,Bilirubin increased,Investigations,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007772,S00432,400,415,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0007773,S00432,213,236,Aphasia,Nervous system disorders,5,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007774,S00432,641,667,Tachycardia,Cardiac disorders,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0007775,S00432,101,123,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0007776,S00432,206,214,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007777,S00432,450,456,Confusional state,Psychiatric disorders,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007778,S00432,169,173,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007779,S00432,240,244,Alanine aminotransferase increased,Investigations,3,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0007780,S00432,726,743,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007781,S00432,661,664,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007782,S00433,3,15,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,3,Y,Y,Corticosteroids,Recovered,N,0,Y,3,N,N,Y
AE0007783,S00433,669,697,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0007784,S00433,514,530,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007785,S00433,420,426,Alanine aminotransferase increased,Investigations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007786,S00433,542,549,Cytomegalovirus infection,Infections and infestations,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007787,S00433,131,142,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007788,S00433,264,274,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007789,S00433,384,394,Sepsis,Infections and infestations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007790,S00433,563,585,Sepsis,Infections and infestations,3,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007791,S00433,131,142,Confusional state,Psychiatric disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007792,S00433,721,748,Sepsis,Infections and infestations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007793,S00433,252,281,Pyrexia,General disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007794,S00433,29,45,Thrombocytopenia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007795,S00433,197,205,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007796,S00433,613,629,Mucosal inflammation,Gastrointestinal disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007797,S00433,580,584,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007798,S00433,336,350,Infusion related reaction,"Injury, poisoning, procedural",4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007799,S00433,263,283,Alanine aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007800,S00433,647,655,Pyrexia,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007801,S00433,264,283,Aphasia,Nervous system disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007802,S00433,32,52,Headache,Nervous system disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0007803,S00433,254,271,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007804,S00433,515,517,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007805,S00433,201,225,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007806,S00433,36,59,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007807,S00434,152,167,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007808,S00434,51,66,Diarrhoea,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007809,S00434,607,630,Diarrhoea,Gastrointestinal disorders,3,N,N,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0007810,S00434,506,524,Vomiting,Gastrointestinal disorders,3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007811,S00434,182,187,Tremor,Nervous system disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007812,S00434,425,437,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007813,S00434,517,539,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007814,S00434,540,552,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007815,S00434,308,309,Tremor,Nervous system disorders,3,Y,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007816,S00434,75,77,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007817,S00434,592,594,Alanine aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0007818,S00434,149,176,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007819,S00434,433,460,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007820,S00434,639,659,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007821,S00434,527,529,Hypotension,Vascular disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007822,S00434,591,600,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007823,S00434,70,76,Aphasia,Nervous system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007824,S00434,475,477,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007825,S00434,162,174,Sepsis,Infections and infestations,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007826,S00434,580,593,Cytomegalovirus infection,Infections and infestations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007827,S00434,234,256,Complement activation,Immune system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007828,S00434,71,84,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007829,S00434,174,201,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007830,S00434,668,679,Bilirubin increased,Investigations,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007831,S00434,629,652,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007832,S00434,404,409,Anaemia,Blood and lymphatic system,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007833,S00434,720,746,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007834,S00434,35,57,Complement activation,Immune system disorders,2,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0007835,S00434,40,58,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007836,S00434,568,581,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007837,S00434,507,518,Seizure,Nervous system disorders,4,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007838,S00434,162,177,Pyrexia,General disorders,3,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007839,S00434,243,265,Headache,Nervous system disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007840,S00434,193,201,Confusional state,Psychiatric disorders,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0007841,S00435,277,279,Cytomegalovirus infection,Infections and infestations,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007842,S00435,700,714,Sepsis,Infections and infestations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007843,S00435,545,566,Sepsis,Infections and infestations,5,Y,N,None,Recovering,N,0,N,0,N,N,N
AE0007844,S00435,195,216,Complement activation,Immune system disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007845,S00435,18,40,Cough,"Respiratory, thoracic, mediastinal",3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007846,S00435,42,52,Confusional state,Psychiatric disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007847,S00435,519,536,Bilirubin increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007848,S00435,112,136,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007849,S00435,57,75,Mucosal inflammation,Gastrointestinal disorders,3,Y,N,None,Recovering,N,0,N,0,N,N,N
AE0007850,S00435,41,58,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007851,S00435,630,643,Headache,Nervous system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007852,S00435,542,563,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007853,S00435,712,728,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007854,S00436,326,354,Bilirubin increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007855,S00436,34,50,Confusional state,Psychiatric disorders,3,Y,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0007856,S00436,431,438,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007857,S00436,24,34,Hypotension,Vascular disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0007858,S00436,127,145,Nausea,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007859,S00436,644,650,Sepsis,Infections and infestations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007860,S00436,240,254,Nausea,Gastrointestinal disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007861,S00436,126,135,Complement activation,Immune system disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007862,S00437,698,710,Bilirubin increased,Investigations,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007863,S00437,303,314,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007864,S00437,697,716,Pyrexia,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007865,S00437,161,166,Aspartate aminotransferase increased,Investigations,3,Y,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007866,S00437,3,16,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007867,S00437,167,186,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007868,S00437,14,23,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007869,S00437,368,374,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007870,S00437,211,215,Sepsis,Infections and infestations,4,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007871,S00437,166,192,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007872,S00438,31,52,Confusional state,Psychiatric disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007873,S00438,51,73,Hypotension,Vascular disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007874,S00438,56,69,Seizure,Nervous system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007875,S00438,274,278,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007876,S00438,355,383,Diarrhoea,Gastrointestinal disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007877,S00438,564,573,Aphasia,Nervous system disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007878,S00438,370,388,Complement activation,Immune system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007879,S00438,605,613,Thrombocytopenia,Blood and lymphatic system,4,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0007880,S00438,494,506,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0007881,S00438,241,256,Tremor,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007882,S00438,682,685,Aphasia,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007883,S00438,605,607,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007884,S00438,3,17,Aphasia,Nervous system disorders,5,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007885,S00438,33,40,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007886,S00438,447,473,Thrombocytopenia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007887,S00438,685,708,Anaemia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007888,S00438,323,350,Bilirubin increased,Investigations,3,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007889,S00439,5,10,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0007890,S00439,596,619,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007891,S00439,542,563,Hypotension,Vascular disorders,5,Y,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007892,S00439,151,159,Anaemia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007893,S00439,445,459,Aphasia,Nervous system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007894,S00439,452,476,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007895,S00439,393,395,Sepsis,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007896,S00439,432,433,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007897,S00439,167,171,Tachycardia,Cardiac disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007898,S00439,42,44,Anaemia,Blood and lymphatic system,2,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007899,S00439,360,389,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0007900,S00439,214,235,Sepsis,Infections and infestations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007901,S00439,676,697,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0007902,S00439,42,47,Complement activation,Immune system disorders,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0007903,S00439,599,623,Tachycardia,Cardiac disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007904,S00439,389,407,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007905,S00439,587,589,Seizure,Nervous system disorders,4,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0007906,S00439,141,144,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007907,S00439,123,137,Vomiting,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007908,S00439,212,219,Hypotension,Vascular disorders,4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007909,S00439,593,619,Aphasia,Nervous system disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007910,S00439,63,81,Complement activation,Immune system disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007911,S00439,198,227,Sepsis,Infections and infestations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007912,S00439,396,409,Neutropenia,Blood and lymphatic system,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007913,S00439,353,356,Diarrhoea,Gastrointestinal disorders,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007914,S00439,334,356,Fatigue,General disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007915,S00439,513,542,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007916,S00439,584,596,Thrombocytopenia,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007917,S00440,238,267,Thrombocytopenia,Blood and lymphatic system,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007918,S00440,587,593,Infusion related reaction,"Injury, poisoning, procedural",3,Y,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0007919,S00440,465,475,Diarrhoea,Gastrointestinal disorders,3,Y,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0007920,S00440,535,559,Headache,Nervous system disorders,3,Y,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007921,S00440,650,671,Thrombocytopenia,Blood and lymphatic system,3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007922,S00440,218,223,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007923,S00440,439,463,Aphasia,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007924,S00440,226,241,Anaemia,Blood and lymphatic system,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0007925,S00440,668,684,Seizure,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007926,S00440,393,411,Aspartate aminotransferase increased,Investigations,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007927,S00440,8,31,Fatigue,General disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007928,S00440,328,355,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Not recovered,N,0,N,0,N,Y,Y
AE0007929,S00440,52,81,Headache,Nervous system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007930,S00440,510,517,Confusional state,Psychiatric disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007931,S00440,126,153,Cytomegalovirus infection,Infections and infestations,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007932,S00440,402,423,Bilirubin increased,Investigations,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0007933,S00440,220,227,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0007934,S00440,690,692,Tachycardia,Cardiac disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007935,S00440,481,508,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007936,S00440,15,17,Neutropenia,Blood and lymphatic system,1,N,Y,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0007937,S00440,205,223,Pyrexia,General disorders,2,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0007938,S00440,339,354,Tremor,Nervous system disorders,1,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0007939,S00440,548,564,Cytomegalovirus infection,Infections and infestations,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007940,S00440,75,98,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007941,S00440,341,370,Fatigue,General disorders,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007942,S00440,276,299,Nausea,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007943,S00440,360,379,Tachycardia,Cardiac disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0007944,S00440,548,570,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007945,S00441,5,18,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0007946,S00441,681,696,Seizure,Nervous system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007947,S00441,307,310,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007948,S00441,638,651,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007949,S00441,42,53,Complement activation,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007950,S00441,620,634,Alanine aminotransferase increased,Investigations,1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0007951,S00441,239,243,Thrombocytopenia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007952,S00441,501,504,Fatigue,General disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0007953,S00441,249,269,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007954,S00441,235,262,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0007955,S00441,275,286,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007956,S00441,207,223,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007957,S00441,294,323,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007958,S00441,702,711,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007959,S00443,7,25,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0007960,S00443,10,14,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0007961,S00443,681,690,Sepsis,Infections and infestations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007962,S00443,130,144,Infusion related reaction,"Injury, poisoning, procedural",3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007963,S00443,590,603,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007964,S00443,586,598,Tachycardia,Cardiac disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007965,S00443,390,419,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007966,S00443,551,572,Thrombocytopenia,Blood and lymphatic system,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007967,S00443,353,380,Confusional state,Psychiatric disorders,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0007968,S00443,182,187,Nausea,Gastrointestinal disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0007969,S00443,567,569,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0007970,S00443,597,607,Hypotension,Vascular disorders,2,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0007971,S00443,176,177,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007972,S00443,104,121,Fatigue,General disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007973,S00443,193,222,Tachycardia,Cardiac disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007974,S00444,93,112,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007975,S00444,500,527,Alanine aminotransferase increased,Investigations,4,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0007976,S00444,572,591,Thrombocytopenia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007977,S00444,564,590,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007978,S00444,97,118,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007979,S00444,444,459,Pyrexia,General disorders,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0007980,S00444,598,609,Hypogammaglobulinaemia,Immune system disorders,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007981,S00445,188,201,Thrombocytopenia,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007982,S00445,659,671,Bilirubin increased,Investigations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0007983,S00445,272,276,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007984,S00445,367,374,Neutropenia,Blood and lymphatic system,2,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0007985,S00445,234,235,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0007986,S00445,343,349,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0007987,S00445,333,335,Aphasia,Nervous system disorders,2,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0007988,S00445,332,356,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007989,S00445,646,667,Seizure,Nervous system disorders,3,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0007990,S00445,296,321,Seizure,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007991,S00445,410,427,Complement activation,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007992,S00445,84,100,Vomiting,Gastrointestinal disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0007993,S00445,348,354,Sepsis,Infections and infestations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0007994,S00445,674,691,Seizure,Nervous system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0007995,S00446,3,13,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0007996,S00446,479,496,Tremor,Nervous system disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0007997,S00446,72,100,Hypogammaglobulinaemia,Immune system disorders,3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0007998,S00446,353,354,Cough,"Respiratory, thoracic, mediastinal",3,Y,N,None,Recovering,N,0,N,0,N,N,N
AE0007999,S00446,713,742,Anaemia,Blood and lymphatic system,3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008000,S00446,101,122,Pyrexia,General disorders,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008001,S00446,548,560,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008002,S00446,226,246,Bilirubin increased,Investigations,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0008003,S00446,630,643,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008004,S00446,481,483,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0008005,S00446,126,135,Infusion related reaction,"Injury, poisoning, procedural",3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0008006,S00446,182,199,Thrombocytopenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008007,S00446,256,275,Sepsis,Infections and infestations,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008008,S00446,729,739,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008009,S00446,308,314,Confusional state,Psychiatric disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008010,S00446,241,256,Anaemia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008011,S00446,269,288,Diarrhoea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008012,S00446,258,269,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008013,S00446,611,623,Complement activation,Immune system disorders,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0008014,S00446,241,259,Tremor,Nervous system disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0008015,S00446,267,275,Hypogammaglobulinaemia,Immune system disorders,2,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0008016,S00446,383,396,Fatigue,General disorders,1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0008017,S00446,324,331,Tachycardia,Cardiac disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008018,S00446,395,418,Seizure,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008019,S00446,506,521,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008020,S00446,186,200,Neutropenia,Blood and lymphatic system,2,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0008021,S00446,700,717,Tremor,Nervous system disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0008022,S00446,92,117,Sepsis,Infections and infestations,4,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008023,S00446,468,483,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008024,S00446,559,586,Aphasia,Nervous system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008025,S00446,7,14,Bilirubin increased,Investigations,1,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0008026,S00446,457,479,Pyrexia,General disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008027,S00446,662,666,Pyrexia,General disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008028,S00446,317,344,Fatigue,General disorders,1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0008029,S00446,618,641,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0008030,S00446,181,207,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008031,S00446,76,90,Confusional state,Psychiatric disorders,3,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0008032,S00446,351,380,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008033,S00447,108,127,Fatigue,General disorders,1,N,Y,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0008034,S00447,54,63,Seizure,Nervous system disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008035,S00447,467,478,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0008036,S00447,475,484,Hypotension,Vascular disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008037,S00447,510,514,Fatigue,General disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008038,S00447,200,229,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008039,S00447,175,182,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008040,S00447,325,353,Diarrhoea,Gastrointestinal disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008041,S00447,46,50,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008042,S00447,172,185,Complement activation,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008043,S00447,274,296,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008044,S00447,312,332,Aphasia,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008045,S00447,476,492,Alanine aminotransferase increased,Investigations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008046,S00447,717,729,Vomiting,Gastrointestinal disorders,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008047,S00447,343,354,Tremor,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008048,S00447,492,518,Mucosal inflammation,Gastrointestinal disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008049,S00447,369,393,Fatigue,General disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008050,S00447,110,139,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008051,S00447,144,157,Confusional state,Psychiatric disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0008052,S00448,670,683,Pyrexia,General disorders,3,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0008053,S00448,329,352,Bilirubin increased,Investigations,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008054,S00448,539,547,Pyrexia,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008055,S00448,290,314,Sepsis,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008056,S00448,714,732,Hypotension,Vascular disorders,2,N,N,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0008057,S00448,450,457,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008058,S00448,54,77,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008059,S00448,613,636,Seizure,Nervous system disorders,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008060,S00448,599,608,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008061,S00448,725,747,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Dose modification,Recovered,N,0,N,0,N,Y,Y
AE0008062,S00449,499,527,Sepsis,Infections and infestations,4,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0008063,S00449,26,55,Vomiting,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008064,S00449,501,514,Neutropenia,Blood and lymphatic system,1,N,Y,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0008065,S00449,447,474,Hypotension,Vascular disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008066,S00449,342,349,Infusion related reaction,"Injury, poisoning, procedural",3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008067,S00449,327,355,Aphasia,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008068,S00449,326,344,Headache,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008069,S00449,538,554,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008070,S00449,431,445,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,Y,Y
AE0008071,S00449,692,714,Aspartate aminotransferase increased,Investigations,1,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0008072,S00449,523,544,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0008073,S00450,89,106,Neutropenia,Blood and lymphatic system,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0008074,S00450,193,210,Tremor,Nervous system disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0008075,S00450,241,242,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008076,S00450,605,607,Aphasia,Nervous system disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008077,S00450,699,714,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008078,S00451,496,518,Vomiting,Gastrointestinal disorders,3,Y,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0008079,S00451,434,440,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,Concomitant medication,Not recovered,N,0,N,0,N,Y,Y
AE0008080,S00451,1,22,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008081,S00451,472,497,Thrombocytopenia,Blood and lymphatic system,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0008082,S00451,353,357,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0008083,S00451,369,397,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008084,S00451,542,555,Hypotension,Vascular disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008085,S00451,171,192,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008086,S00451,587,597,Seizure,Nervous system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0008087,S00451,471,488,Neutropenia,Blood and lymphatic system,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008088,S00451,356,364,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0008089,S00451,84,89,Vomiting,Gastrointestinal disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008090,S00451,421,427,Vomiting,Gastrointestinal disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008091,S00452,5,18,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0008092,S00452,10,19,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,2,N,Y,Corticosteroids,Recovered,N,0,Y,2,N,N,Y
AE0008093,S00452,235,239,Diarrhoea,Gastrointestinal disorders,3,Y,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0008094,S00452,478,487,Mucosal inflammation,Gastrointestinal disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008095,S00452,278,286,Headache,Nervous system disorders,3,Y,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0008096,S00452,371,373,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008097,S00452,432,444,Nausea,Gastrointestinal disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008098,S00452,533,534,Thrombocytopenia,Blood and lymphatic system,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0008099,S00452,58,84,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008100,S00452,671,690,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008101,S00452,441,451,Tachycardia,Cardiac disorders,1,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0008102,S00452,446,448,Cytomegalovirus infection,Infections and infestations,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008103,S00452,325,338,Seizure,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008104,S00452,369,374,Bilirubin increased,Investigations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0008105,S00452,215,225,Fatigue,General disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008106,S00452,184,198,Aphasia,Nervous system disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008107,S00452,37,54,Nausea,Gastrointestinal disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0008108,S00452,549,578,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0008109,S00452,591,617,Aspartate aminotransferase increased,Investigations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008110,S00452,259,284,Complement activation,Immune system disorders,2,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0008111,S00452,249,269,Complement activation,Immune system disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0008112,S00452,499,511,Tremor,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008113,S00452,321,325,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0008114,S00452,415,432,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008115,S00452,103,128,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008116,S00452,194,196,Cytomegalovirus infection,Infections and infestations,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008117,S00452,510,528,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008118,S00452,138,157,Anaemia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008119,S00452,1,21,Tremor,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008120,S00452,54,66,Neutropenia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008121,S00452,264,266,Bilirubin increased,Investigations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008122,S00452,434,463,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008123,S00452,621,640,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008124,S00452,530,533,Aphasia,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008125,S00452,97,115,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008126,S00452,248,252,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Dose modification,Fatal,N,0,N,0,N,N,N
AE0008127,S00452,16,21,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,Y,Y
AE0008128,S00452,565,587,Sepsis,Infections and infestations,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008129,S00452,662,675,Complement activation,Immune system disorders,2,N,N,None,Fatal,N,0,N,0,N,N,N
AE0008130,S00452,382,383,Hypotension,Vascular disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008131,S00453,4,13,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0008132,S00453,4,23,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0008133,S00453,130,138,Alanine aminotransferase increased,Investigations,3,Y,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0008134,S00453,390,416,Neutropenia,Blood and lymphatic system,3,Y,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008135,S00453,615,637,Aphasia,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008136,S00453,723,745,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008137,S00453,493,512,Aphasia,Nervous system disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008138,S00453,698,720,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008139,S00453,233,258,Complement activation,Immune system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008140,S00453,573,583,Vomiting,Gastrointestinal disorders,2,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0008141,S00453,118,143,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008142,S00453,248,265,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008143,S00453,103,105,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008144,S00453,552,578,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Unknown,N,0,N,0,N,Y,Y
AE0008145,S00453,11,39,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008146,S00453,599,619,Neutropenia,Blood and lymphatic system,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008147,S00453,153,180,Pyrexia,General disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008148,S00453,363,376,Alanine aminotransferase increased,Investigations,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008149,S00453,591,598,Alanine aminotransferase increased,Investigations,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0008150,S00453,603,617,Anaemia,Blood and lymphatic system,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008151,S00453,74,80,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008152,S00453,44,53,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008153,S00453,137,161,Fatigue,General disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008154,S00453,62,82,Fatigue,General disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008155,S00453,483,488,Bilirubin increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008156,S00453,142,156,Tachycardia,Cardiac disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008157,S00453,90,107,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008158,S00453,58,72,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008159,S00453,468,495,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0008160,S00453,242,244,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008161,S00453,292,308,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008162,S00453,324,349,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008163,S00453,454,462,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008164,S00454,52,74,Headache,Nervous system disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008165,S00454,27,38,Alanine aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0008166,S00454,170,193,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008167,S00454,64,72,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008168,S00454,513,527,Sepsis,Infections and infestations,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008169,S00454,636,642,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008170,S00454,632,657,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0008171,S00454,571,599,Bilirubin increased,Investigations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008172,S00454,616,631,Neutropenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008173,S00454,706,717,Thrombocytopenia,Blood and lymphatic system,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008174,S00454,484,485,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008175,S00454,617,618,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008176,S00454,388,417,Cytomegalovirus infection,Infections and infestations,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008177,S00454,175,176,Anaemia,Blood and lymphatic system,1,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0008178,S00454,520,521,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008179,S00455,325,346,Tachycardia,Cardiac disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0008180,S00455,59,63,Confusional state,Psychiatric disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008181,S00455,316,318,Aspartate aminotransferase increased,Investigations,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008182,S00455,449,470,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008183,S00455,455,469,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,Drug interrupted,Recovering,N,0,N,0,N,Y,Y
AE0008184,S00455,25,31,Vomiting,Gastrointestinal disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008185,S00455,145,173,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008186,S00455,15,32,Anaemia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008187,S00455,492,505,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008188,S00455,205,233,Sepsis,Infections and infestations,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0008189,S00455,639,643,Aphasia,Nervous system disorders,1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0008190,S00455,365,381,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008191,S00455,592,619,Anaemia,Blood and lymphatic system,1,N,Y,Drug interrupted,Fatal,N,0,N,0,N,N,N
AE0008192,S00455,245,272,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008193,S00456,13,42,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008194,S00456,11,40,Fatigue,General disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008195,S00456,703,723,Cytomegalovirus infection,Infections and infestations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008196,S00456,450,469,Sepsis,Infections and infestations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008197,S00456,469,471,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0008198,S00456,117,123,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Recovering,N,0,N,0,N,Y,Y
AE0008199,S00456,4,16,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0008200,S00456,71,100,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0008201,S00456,4,29,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,Dose modification,Recovered,N,0,N,0,N,Y,Y
AE0008202,S00456,71,92,Confusional state,Psychiatric disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008203,S00456,196,219,Headache,Nervous system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008204,S00456,330,339,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008205,S00456,267,270,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0008206,S00457,517,520,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008207,S00457,564,577,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008208,S00457,73,100,Tachycardia,Cardiac disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008209,S00457,637,640,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008210,S00457,682,693,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008211,S00457,179,207,Cytomegalovirus infection,Infections and infestations,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008212,S00457,610,635,Seizure,Nervous system disorders,2,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0008213,S00457,652,656,Sepsis,Infections and infestations,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008214,S00457,619,631,Fatigue,General disorders,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008215,S00457,661,690,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008216,S00457,28,53,Tremor,Nervous system disorders,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0008217,S00457,318,320,Alanine aminotransferase increased,Investigations,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008218,S00457,281,294,Vomiting,Gastrointestinal disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008219,S00457,99,104,Thrombotic microangiopathy,Blood and lymphatic system,5,N,N,Drug interrupted,Recovering,N,0,N,0,N,Y,Y
AE0008220,S00457,635,662,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0008221,S00457,684,693,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008222,S00457,476,502,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008223,S00457,472,483,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008224,S00457,550,564,Mucosal inflammation,Gastrointestinal disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008225,S00457,247,265,Anaemia,Blood and lymphatic system,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0008226,S00457,560,582,Diarrhoea,Gastrointestinal disorders,1,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0008227,S00457,658,667,Aphasia,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008228,S00457,298,322,Anaemia,Blood and lymphatic system,3,N,N,None,Fatal,N,0,N,0,N,N,N
AE0008229,S00459,3,8,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0008230,S00459,31,50,Tremor,Nervous system disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0008231,S00459,728,743,Hypoxia,"Respiratory, thoracic, mediastinal",3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0008232,S00459,82,106,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0008233,S00459,171,180,Anaemia,Blood and lymphatic system,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0008234,S00459,283,307,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008235,S00459,58,81,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008236,S00459,250,261,Bilirubin increased,Investigations,4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008237,S00459,121,150,Vomiting,Gastrointestinal disorders,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0008238,S00459,542,571,Alanine aminotransferase increased,Investigations,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0008239,S00459,727,747,Tachycardia,Cardiac disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008240,S00459,525,528,Fatigue,General disorders,1,N,Y,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0008241,S00459,454,456,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008242,S00459,74,84,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008243,S00459,135,142,Pyrexia,General disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0008244,S00459,327,333,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008245,S00459,424,448,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008246,S00459,318,346,Complement activation,Immune system disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008247,S00459,104,130,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0008248,S00459,637,644,Seizure,Nervous system disorders,5,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0008249,S00459,170,185,Diarrhoea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008250,S00459,135,160,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008251,S00459,506,532,Pyrexia,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008252,S00459,522,550,Thrombocytopenia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008253,S00459,657,661,Complement activation,Immune system disorders,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008254,S00459,665,682,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008255,S00459,711,735,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008256,S00459,60,82,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008257,S00459,264,284,Sepsis,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008258,S00460,1,13,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0008259,S00460,214,232,Thrombocytopenia,Blood and lymphatic system,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008260,S00460,702,718,Fatigue,General disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008261,S00460,567,569,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008262,S00460,369,391,Hypotension,Vascular disorders,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0008263,S00460,486,499,Neutropenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008264,S00460,376,377,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008265,S00460,389,410,Mucosal inflammation,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008266,S00460,413,424,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008267,S00460,44,56,Vomiting,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008268,S00460,79,80,Confusional state,Psychiatric disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008269,S00460,307,321,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008270,S00460,322,350,Diarrhoea,Gastrointestinal disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0008271,S00460,171,190,Bilirubin increased,Investigations,1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0008272,S00460,670,696,Bilirubin increased,Investigations,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008273,S00460,5,9,Alanine aminotransferase increased,Investigations,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008274,S00460,16,42,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008275,S00460,167,184,Complement activation,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008276,S00460,163,168,Headache,Nervous system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008277,S00460,697,723,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008278,S00460,723,728,Thrombocytopenia,Blood and lymphatic system,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0008279,S00460,68,93,Diarrhoea,Gastrointestinal disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008280,S00460,285,300,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008281,S00460,202,216,Anaemia,Blood and lymphatic system,1,N,N,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0008282,S00460,405,406,Fatigue,General disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008283,S00460,12,22,Bilirubin increased,Investigations,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008284,S00460,172,180,Bilirubin increased,Investigations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008285,S00461,186,194,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008286,S00461,169,195,Mucosal inflammation,Gastrointestinal disorders,3,Y,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0008287,S00461,266,287,Aphasia,Nervous system disorders,5,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008288,S00461,376,402,Complement activation,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008289,S00461,468,485,Tachycardia,Cardiac disorders,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0008290,S00461,467,471,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008291,S00461,469,477,Nausea,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008292,S00461,726,745,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008293,S00461,339,366,Complement activation,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008294,S00461,427,439,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008295,S00461,206,211,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0008296,S00462,713,715,Cytomegalovirus infection,Infections and infestations,5,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0008297,S00462,650,675,Sepsis,Infections and infestations,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008298,S00462,693,714,Neutropenia,Blood and lymphatic system,1,N,Y,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0008299,S00462,185,214,Sepsis,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008300,S00462,567,589,Sepsis,Infections and infestations,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008301,S00462,575,601,Anaemia,Blood and lymphatic system,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0008302,S00462,643,661,Seizure,Nervous system disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008303,S00462,91,102,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008304,S00462,136,154,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0008305,S00462,216,230,Diarrhoea,Gastrointestinal disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008306,S00462,111,114,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,Concomitant medication,Fatal,N,0,N,0,N,Y,Y
AE0008307,S00462,390,401,Alanine aminotransferase increased,Investigations,4,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0008308,S00462,236,264,Bilirubin increased,Investigations,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008309,S00462,647,653,Anaemia,Blood and lymphatic system,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0008310,S00462,370,391,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008311,S00462,141,153,Complement activation,Immune system disorders,5,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008312,S00462,565,579,Pyrexia,General disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0008313,S00462,326,352,Anaemia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0008314,S00463,191,206,Confusional state,Psychiatric disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0008315,S00463,693,695,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008316,S00463,210,212,Vomiting,Gastrointestinal disorders,3,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0008317,S00463,531,559,Headache,Nervous system disorders,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008318,S00463,546,565,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008319,S00463,113,124,Sepsis,Infections and infestations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008320,S00463,33,36,Seizure,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008321,S00463,604,633,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008322,S00463,533,540,Thrombocytopenia,Blood and lymphatic system,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0008323,S00463,476,489,Vomiting,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008324,S00463,0,4,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008325,S00463,715,734,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008326,S00463,344,372,Seizure,Nervous system disorders,2,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0008327,S00463,367,388,Neutropenia,Blood and lymphatic system,4,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0008328,S00463,391,402,Alanine aminotransferase increased,Investigations,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008329,S00464,320,338,Sepsis,Infections and infestations,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008330,S00464,556,566,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008331,S00464,401,424,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008332,S00464,709,732,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0008333,S00464,178,192,Aphasia,Nervous system disorders,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008334,S00464,547,563,Aspartate aminotransferase increased,Investigations,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008335,S00464,558,564,Pyrexia,General disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008336,S00464,55,67,Cytomegalovirus infection,Infections and infestations,2,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0008337,S00464,570,573,Pyrexia,General disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008338,S00464,395,396,Aphasia,Nervous system disorders,5,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0008339,S00464,664,670,Fatigue,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008340,S00464,176,200,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008341,S00464,101,121,Seizure,Nervous system disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0008342,S00464,271,282,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008343,S00464,248,268,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008344,S00465,58,86,Headache,Nervous system disorders,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0008345,S00465,113,138,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008346,S00465,722,739,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008347,S00465,518,525,Alanine aminotransferase increased,Investigations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0008348,S00465,667,670,Cytomegalovirus infection,Infections and infestations,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008349,S00465,656,668,Pyrexia,General disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008350,S00465,111,132,Pyrexia,General disorders,2,N,N,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0008351,S00465,323,332,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008352,S00465,584,603,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Not recovered,N,0,N,0,N,Y,Y
AE0008353,S00465,380,397,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008354,S00465,190,210,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0008355,S00465,301,330,Tremor,Nervous system disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008356,S00465,415,431,Seizure,Nervous system disorders,5,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008357,S00465,429,434,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008358,S00465,322,342,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008359,S00466,1,12,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0008360,S00466,93,94,Complement activation,Immune system disorders,3,Y,N,None,Recovering,N,0,N,0,N,N,N
AE0008361,S00466,565,571,Anaemia,Blood and lymphatic system,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0008362,S00466,323,327,Headache,Nervous system disorders,2,N,N,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0008363,S00466,289,290,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008364,S00466,693,717,Anaemia,Blood and lymphatic system,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008365,S00466,133,136,Vomiting,Gastrointestinal disorders,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0008366,S00466,163,182,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0008367,S00466,600,629,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008368,S00466,198,216,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008369,S00466,145,170,Tachycardia,Cardiac disorders,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0008370,S00466,627,649,Diarrhoea,Gastrointestinal disorders,1,N,N,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0008371,S00466,474,486,Aphasia,Nervous system disorders,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0008372,S00466,705,714,Tachycardia,Cardiac disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008373,S00466,653,657,Hypotension,Vascular disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008374,S00466,547,576,Fatigue,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008375,S00466,349,356,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008376,S00466,425,436,Cytomegalovirus infection,Infections and infestations,3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008377,S00466,4,19,Nausea,Gastrointestinal disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008378,S00466,447,464,Sepsis,Infections and infestations,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008379,S00466,386,388,Tachycardia,Cardiac disorders,1,N,N,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0008380,S00466,448,469,Aphasia,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008381,S00466,456,477,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008382,S00466,663,686,Alanine aminotransferase increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008383,S00466,303,304,Neutropenia,Blood and lymphatic system,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0008384,S00466,646,659,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008385,S00466,405,407,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008386,S00466,720,738,Pyrexia,General disorders,1,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0008387,S00466,3,12,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008388,S00467,470,491,Vomiting,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0008389,S00467,471,477,Hypotension,Vascular disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008390,S00467,129,145,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0008391,S00467,566,587,Diarrhoea,Gastrointestinal disorders,3,Y,N,None,Recovering,N,0,N,0,N,N,N
AE0008392,S00467,280,308,Seizure,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008393,S00467,712,714,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0008394,S00467,579,583,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0008395,S00467,564,591,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008396,S00467,79,83,Alanine aminotransferase increased,Investigations,4,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0008397,S00467,372,386,Vomiting,Gastrointestinal disorders,1,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0008398,S00467,80,98,Confusional state,Psychiatric disorders,1,N,N,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0008399,S00467,607,628,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,Drug interrupted,Recovering,N,0,N,0,N,Y,Y
AE0008400,S00467,193,218,Nausea,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008401,S00467,220,233,Bilirubin increased,Investigations,1,N,N,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0008402,S00467,512,535,Neutropenia,Blood and lymphatic system,1,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0008403,S00467,436,447,Seizure,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008404,S00467,562,563,Headache,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008405,S00467,512,522,Confusional state,Psychiatric disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0008406,S00467,136,157,Vomiting,Gastrointestinal disorders,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0008407,S00467,362,388,Infusion related reaction,"Injury, poisoning, procedural",3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008408,S00467,295,299,Hypotension,Vascular disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008409,S00467,214,216,Infusion related reaction,"Injury, poisoning, procedural",4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008410,S00467,335,353,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008411,S00467,7,20,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0008412,S00467,588,607,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008413,S00467,424,431,Seizure,Nervous system disorders,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008414,S00467,642,652,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008415,S00467,162,185,Sepsis,Infections and infestations,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008416,S00467,594,600,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008417,S00467,440,454,Tachycardia,Cardiac disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008418,S00467,80,95,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0008419,S00467,395,396,Nausea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008420,S00467,454,456,Seizure,Nervous system disorders,3,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0008421,S00467,72,87,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008422,S00468,119,138,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0008423,S00468,728,730,Aphasia,Nervous system disorders,3,Y,Y,None,Recovering,N,0,N,0,N,N,N
AE0008424,S00468,712,717,Aspartate aminotransferase increased,Investigations,1,N,Y,Dose modification,Unknown,N,0,N,0,N,N,N
AE0008425,S00468,384,399,Pyrexia,General disorders,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0008426,S00468,467,476,Tachycardia,Cardiac disorders,3,Y,Y,None,Not recovered,N,0,N,0,N,N,N
AE0008427,S00468,617,635,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008428,S00468,391,420,Complement activation,Immune system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008429,S00468,360,374,Cough,"Respiratory, thoracic, mediastinal",3,Y,N,None,Recovering,N,0,N,0,N,N,N
AE0008430,S00468,135,140,Sepsis,Infections and infestations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008431,S00468,94,114,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008432,S00468,301,323,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0008433,S00468,212,216,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008434,S00468,394,421,Confusional state,Psychiatric disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008435,S00468,556,577,Aphasia,Nervous system disorders,5,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0008436,S00468,495,522,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008437,S00468,407,418,Nausea,Gastrointestinal disorders,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008438,S00468,156,161,Headache,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0008439,S00468,448,463,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008440,S00468,145,150,Pyrexia,General disorders,1,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0008441,S00468,470,485,Complement activation,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008442,S00468,661,666,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008443,S00468,390,398,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008444,S00468,202,231,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008445,S00468,409,425,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008446,S00470,531,534,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008447,S00470,431,446,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,Y,Y
AE0008448,S00470,134,137,Nausea,Gastrointestinal disorders,1,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0008449,S00470,176,202,Tremor,Nervous system disorders,3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008450,S00470,581,610,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008451,S00470,449,465,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008452,S00470,244,247,Tremor,Nervous system disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0008453,S00470,489,492,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008454,S00470,622,624,Nausea,Gastrointestinal disorders,4,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0008455,S00471,395,417,Infusion related reaction,"Injury, poisoning, procedural",4,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008456,S00471,160,177,Diarrhoea,Gastrointestinal disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008457,S00471,400,410,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008458,S00471,162,165,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008459,S00471,158,165,Pyrexia,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008460,S00471,617,632,Thrombocytopenia,Blood and lymphatic system,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008461,S00471,423,424,Confusional state,Psychiatric disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008462,S00471,154,166,Complement activation,Immune system disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008463,S00471,252,253,Headache,Nervous system disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0008464,S00471,22,33,Headache,Nervous system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008465,S00471,280,307,Confusional state,Psychiatric disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008466,S00471,498,509,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0008467,S00471,461,480,Confusional state,Psychiatric disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008468,S00471,318,336,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008469,S00472,384,390,Complement activation,Immune system disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008470,S00472,39,47,Seizure,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008471,S00472,722,746,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008472,S00472,3,14,Vomiting,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008473,S00472,161,168,Hypotension,Vascular disorders,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0008474,S00472,408,426,Fatigue,General disorders,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008475,S00472,485,495,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008476,S00472,415,423,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Concomitant medication,Recovering,N,0,N,0,N,Y,Y
AE0008477,S00472,80,83,Tremor,Nervous system disorders,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0008478,S00472,637,646,Aphasia,Nervous system disorders,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0008479,S00472,429,446,Aphasia,Nervous system disorders,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008480,S00473,252,263,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,Dose modification,Recovered,N,0,N,0,N,Y,Y
AE0008481,S00473,516,537,Thrombotic microangiopathy,Blood and lymphatic system,3,Y,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0008482,S00473,473,487,Fatigue,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008483,S00473,213,217,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,Hospitalization,Recovering,N,0,N,0,N,Y,Y
AE0008484,S00473,566,587,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008485,S00473,527,528,Hypogammaglobulinaemia,Immune system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008486,S00473,595,600,Seizure,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008487,S00473,160,185,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0008488,S00473,394,407,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008489,S00473,211,232,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008490,S00473,286,307,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,Y,Y
AE0008491,S00474,641,646,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008492,S00474,612,635,Diarrhoea,Gastrointestinal disorders,3,Y,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008493,S00474,253,278,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0008494,S00474,155,177,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008495,S00474,592,614,Confusional state,Psychiatric disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008496,S00474,597,620,Vomiting,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008497,S00475,389,407,Aphasia,Nervous system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008498,S00475,325,354,Tremor,Nervous system disorders,1,N,Y,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0008499,S00475,187,211,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0008500,S00475,262,272,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008501,S00475,399,406,Thrombocytopenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008502,S00475,678,684,Pyrexia,General disorders,1,N,N,Drug interrupted,Fatal,N,0,N,0,N,N,N
AE0008503,S00475,586,610,Hypotension,Vascular disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0008504,S00475,105,113,Complement activation,Immune system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008505,S00475,441,470,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008506,S00475,328,340,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0008507,S00475,396,400,Fatigue,General disorders,1,N,Y,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0008508,S00475,420,443,Tachycardia,Cardiac disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008509,S00475,288,307,Aphasia,Nervous system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008510,S00475,351,364,Anaemia,Blood and lymphatic system,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008511,S00475,250,262,Hypotension,Vascular disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008512,S00475,77,79,Headache,Nervous system disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0008513,S00475,574,585,Vomiting,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008514,S00475,399,423,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008515,S00476,421,427,Headache,Nervous system disorders,3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008516,S00476,671,673,Nausea,Gastrointestinal disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008517,S00476,677,700,Headache,Nervous system disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008518,S00476,311,331,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,Y,Y
AE0008519,S00476,81,96,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0008520,S00476,337,357,Tachycardia,Cardiac disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0008521,S00476,364,380,Nausea,Gastrointestinal disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008522,S00476,176,185,Hypogammaglobulinaemia,Immune system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008523,S00476,690,695,Sepsis,Infections and infestations,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0008524,S00476,705,725,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008525,S00476,557,560,Cough,"Respiratory, thoracic, mediastinal",2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008526,S00476,434,435,Hypotension,Vascular disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008527,S00476,209,235,Confusional state,Psychiatric disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008528,S00476,9,17,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008529,S00476,18,43,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0008530,S00476,532,551,Diarrhoea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008531,S00476,436,445,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008532,S00476,505,531,Alanine aminotransferase increased,Investigations,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008533,S00476,235,255,Pyrexia,General disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008534,S00476,245,246,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0008535,S00476,256,276,Thrombotic microangiopathy,Blood and lymphatic system,5,N,N,Concomitant medication,Recovering,N,0,N,0,N,Y,Y
AE0008536,S00476,640,641,Tachycardia,Cardiac disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008537,S00476,693,697,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008538,S00476,198,206,Cough,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008539,S00477,694,717,Complement activation,Immune system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008540,S00477,59,69,Bilirubin increased,Investigations,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008541,S00477,153,154,Fatigue,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008542,S00477,107,113,Confusional state,Psychiatric disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008543,S00477,302,327,Nausea,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008544,S00477,565,582,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008545,S00477,383,400,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0008546,S00477,338,364,Tachycardia,Cardiac disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008547,S00478,228,255,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0008548,S00478,445,447,Nausea,Gastrointestinal disorders,3,Y,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008549,S00478,574,581,Bilirubin increased,Investigations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008550,S00478,142,166,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008551,S00478,75,87,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0008552,S00478,41,45,Tremor,Nervous system disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0008553,S00478,237,249,Tachycardia,Cardiac disorders,2,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0008554,S00478,210,234,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008555,S00479,7,10,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0008556,S00479,185,186,Aphasia,Nervous system disorders,3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008557,S00479,17,25,Fatigue,General disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008558,S00479,196,220,Complement activation,Immune system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008559,S00479,677,695,Anaemia,Blood and lymphatic system,3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0008560,S00479,482,505,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008561,S00479,557,564,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008562,S00479,22,23,Nausea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008563,S00479,88,101,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008564,S00479,598,611,Sepsis,Infections and infestations,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008565,S00479,654,666,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008566,S00479,160,161,Cytomegalovirus infection,Infections and infestations,2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0008567,S00479,543,570,Cytomegalovirus infection,Infections and infestations,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008568,S00479,702,708,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008569,S00479,410,431,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008570,S00479,367,383,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008571,S00479,291,294,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008572,S00479,205,212,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0008573,S00479,413,425,Cytomegalovirus infection,Infections and infestations,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008574,S00479,428,442,Fatigue,General disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0008575,S00479,420,435,Fatigue,General disorders,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0008576,S00479,654,663,Anaemia,Blood and lymphatic system,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008577,S00479,519,539,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008578,S00479,538,559,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008579,S00481,225,243,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008580,S00481,509,524,Aphasia,Nervous system disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008581,S00481,315,317,Hypotension,Vascular disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008582,S00481,376,387,Diarrhoea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0008583,S00481,461,465,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008584,S00481,290,309,Aphasia,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008585,S00481,458,478,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008586,S00481,161,170,Aphasia,Nervous system disorders,1,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0008587,S00481,535,555,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008588,S00481,522,540,Mucosal inflammation,Gastrointestinal disorders,4,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0008589,S00481,667,695,Aspartate aminotransferase increased,Investigations,4,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0008590,S00481,488,506,Anaemia,Blood and lymphatic system,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0008591,S00481,589,607,Cytomegalovirus infection,Infections and infestations,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0008592,S00481,229,254,Neutropenia,Blood and lymphatic system,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0008593,S00481,544,564,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0008594,S00481,719,736,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,None,Recovering,N,0,N,0,N,Y,Y
AE0008595,S00481,692,700,Bilirubin increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008596,S00481,438,447,Bilirubin increased,Investigations,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008597,S00481,268,278,Tremor,Nervous system disorders,3,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0008598,S00481,65,67,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008599,S00481,656,684,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008600,S00482,523,525,Headache,Nervous system disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008601,S00482,375,398,Bilirubin increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008602,S00482,312,323,Aphasia,Nervous system disorders,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008603,S00482,151,160,Hypogammaglobulinaemia,Immune system disorders,3,Y,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0008604,S00482,72,90,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008605,S00482,49,51,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0008606,S00482,209,217,Headache,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008607,S00482,655,682,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008608,S00482,307,333,Seizure,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008609,S00482,274,282,Infusion related reaction,"Injury, poisoning, procedural",4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008610,S00482,584,594,Thrombocytopenia,Blood and lymphatic system,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0008611,S00482,385,386,Thrombocytopenia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008612,S00482,46,67,Sepsis,Infections and infestations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008613,S00482,282,294,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008614,S00482,709,738,Aphasia,Nervous system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008615,S00483,614,642,Hypogammaglobulinaemia,Immune system disorders,2,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0008616,S00483,293,295,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008617,S00483,457,477,Cytomegalovirus infection,Infections and infestations,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008618,S00483,205,216,Confusional state,Psychiatric disorders,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008619,S00483,409,420,Pyrexia,General disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008620,S00483,187,191,Vomiting,Gastrointestinal disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0008621,S00483,130,146,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008622,S00483,461,467,Anaemia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008623,S00483,504,528,Tremor,Nervous system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008624,S00483,104,129,Vomiting,Gastrointestinal disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0008625,S00483,233,250,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008626,S00483,722,748,Aspartate aminotransferase increased,Investigations,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008627,S00483,729,737,Tachycardia,Cardiac disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008628,S00483,373,389,Seizure,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008629,S00483,310,330,Complement activation,Immune system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008630,S00484,440,458,Alanine aminotransferase increased,Investigations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0008631,S00484,366,376,Anaemia,Blood and lymphatic system,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008632,S00484,566,575,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008633,S00484,238,244,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008634,S00484,483,508,Fatigue,General disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008635,S00484,130,148,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008636,S00484,415,426,Neutropenia,Blood and lymphatic system,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0008637,S00484,226,231,Tachycardia,Cardiac disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008638,S00484,648,677,Aphasia,Nervous system disorders,5,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0008639,S00484,652,664,Headache,Nervous system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008640,S00484,36,53,Nausea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0008641,S00484,293,304,Anaemia,Blood and lymphatic system,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0008642,S00484,141,149,Tachycardia,Cardiac disorders,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008643,S00484,685,702,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008644,S00484,494,501,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008645,S00484,644,648,Diarrhoea,Gastrointestinal disorders,1,N,N,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0008646,S00484,272,291,Fatigue,General disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008647,S00484,214,219,Neutropenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008648,S00485,281,310,Infusion related reaction,"Injury, poisoning, procedural",5,Y,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0008649,S00485,167,192,Thrombocytopenia,Blood and lymphatic system,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0008650,S00485,268,278,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008651,S00485,195,224,Anaemia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008652,S00485,34,58,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008653,S00485,717,741,Thrombocytopenia,Blood and lymphatic system,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008654,S00485,547,575,Thrombocytopenia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008655,S00485,163,182,Seizure,Nervous system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008656,S00485,265,292,Tremor,Nervous system disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0008657,S00485,691,698,Bilirubin increased,Investigations,2,N,Y,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0008658,S00485,624,642,Tremor,Nervous system disorders,4,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008659,S00485,670,696,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0008660,S00486,155,166,Diarrhoea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008661,S00486,143,160,Neutropenia,Blood and lymphatic system,3,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0008662,S00486,445,447,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008663,S00486,235,237,Hypotension,Vascular disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008664,S00486,729,732,Cytomegalovirus infection,Infections and infestations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008665,S00486,303,324,Complement activation,Immune system disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0008666,S00486,250,268,Neutropenia,Blood and lymphatic system,3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0008667,S00486,458,485,Tremor,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0008668,S00486,666,675,Diarrhoea,Gastrointestinal disorders,2,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0008669,S00486,343,344,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0008670,S00486,727,753,Vomiting,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008671,S00488,628,630,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0008672,S00488,661,668,Sepsis,Infections and infestations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008673,S00488,598,624,Aphasia,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008674,S00488,106,128,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008675,S00488,685,693,Hypogammaglobulinaemia,Immune system disorders,5,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008676,S00488,637,650,Aphasia,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008677,S00488,453,456,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008678,S00488,721,724,Diarrhoea,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008679,S00488,670,697,Nausea,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008680,S00488,396,413,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008681,S00488,323,340,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008682,S00488,74,86,Confusional state,Psychiatric disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008683,S00488,207,221,Pyrexia,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008684,S00488,546,557,Bilirubin increased,Investigations,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008685,S00488,422,433,Seizure,Nervous system disorders,5,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008686,S00488,51,65,Aspartate aminotransferase increased,Investigations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0008687,S00488,72,100,Seizure,Nervous system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008688,S00488,131,153,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008689,S00488,354,366,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0008690,S00488,599,622,Diarrhoea,Gastrointestinal disorders,2,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0008691,S00488,360,368,Cytomegalovirus infection,Infections and infestations,2,N,N,None,Fatal,N,0,N,0,N,N,N
AE0008692,S00488,680,687,Fatigue,General disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008693,S00488,190,202,Nausea,Gastrointestinal disorders,3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0008694,S00488,110,130,Neutropenia,Blood and lymphatic system,1,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0008695,S00488,9,36,Bilirubin increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008696,S00488,711,718,Cough,"Respiratory, thoracic, mediastinal",4,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008697,S00488,19,40,Tachycardia,Cardiac disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008698,S00488,421,441,Vomiting,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008699,S00488,135,137,Aphasia,Nervous system disorders,2,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0008700,S00489,558,572,Alanine aminotransferase increased,Investigations,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008701,S00489,572,581,Infusion related reaction,"Injury, poisoning, procedural",3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008702,S00489,222,235,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008703,S00489,642,670,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0008704,S00489,521,540,Neutropenia,Blood and lymphatic system,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008705,S00489,38,51,Aphasia,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008706,S00489,226,228,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008707,S00489,377,387,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,None,Recovering,N,0,N,0,N,Y,Y
AE0008708,S00489,13,39,Pyrexia,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008709,S00489,181,207,Aspartate aminotransferase increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008710,S00489,607,619,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008711,S00489,624,625,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,Y,Y
AE0008712,S00489,27,56,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0008713,S00489,514,523,Seizure,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008714,S00490,348,361,Nausea,Gastrointestinal disorders,2,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0008715,S00490,240,245,Complement activation,Immune system disorders,5,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008716,S00490,359,380,Tachycardia,Cardiac disorders,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008717,S00490,23,37,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008718,S00490,328,336,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0008719,S00490,602,624,Seizure,Nervous system disorders,1,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0008720,S00490,332,337,Seizure,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008721,S00490,524,535,Alanine aminotransferase increased,Investigations,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008722,S00490,414,434,Confusional state,Psychiatric disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008723,S00490,227,237,Tremor,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008724,S00490,728,745,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0008725,S00490,322,345,Mucosal inflammation,Gastrointestinal disorders,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008726,S00490,19,47,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008727,S00490,279,308,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008728,S00491,2,13,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0008729,S00491,602,631,Infusion related reaction,"Injury, poisoning, procedural",3,Y,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0008730,S00491,358,366,Sepsis,Infections and infestations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008731,S00491,469,472,Aspartate aminotransferase increased,Investigations,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008732,S00491,524,543,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008733,S00491,462,476,Bilirubin increased,Investigations,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0008734,S00491,510,527,Nausea,Gastrointestinal disorders,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0008735,S00491,182,188,Hypotension,Vascular disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008736,S00491,651,659,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008737,S00491,388,413,Cytomegalovirus infection,Infections and infestations,3,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0008738,S00491,281,293,Sepsis,Infections and infestations,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008739,S00491,499,520,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008740,S00491,460,462,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008741,S00491,463,482,Vomiting,Gastrointestinal disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008742,S00491,10,13,Thrombocytopenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008743,S00491,9,23,Seizure,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008744,S00491,288,315,Hypotension,Vascular disorders,4,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008745,S00491,85,101,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008746,S00491,208,234,Hypotension,Vascular disorders,4,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0008747,S00491,343,357,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0008748,S00492,3,20,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0008749,S00492,90,104,Tachycardia,Cardiac disorders,3,Y,N,None,Unknown,N,0,N,0,N,N,N
AE0008750,S00492,323,350,Confusional state,Psychiatric disorders,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0008751,S00492,443,471,Alanine aminotransferase increased,Investigations,3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008752,S00492,277,285,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0008753,S00492,353,362,Thrombocytopenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008754,S00492,393,394,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008755,S00492,592,602,Sepsis,Infections and infestations,4,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0008756,S00492,375,383,Sepsis,Infections and infestations,5,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0008757,S00492,89,90,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Not recovered,N,0,N,0,N,Y,Y
AE0008758,S00492,371,376,Pyrexia,General disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008759,S00492,658,679,Neutropenia,Blood and lymphatic system,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008760,S00492,174,177,Sepsis,Infections and infestations,4,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0008761,S00492,495,503,Aphasia,Nervous system disorders,4,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008762,S00492,23,41,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008763,S00492,457,481,Confusional state,Psychiatric disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008764,S00492,655,674,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008765,S00492,204,221,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0008766,S00492,278,295,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008767,S00492,19,31,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008768,S00492,290,309,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008769,S00492,489,518,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0008770,S00492,438,441,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0008771,S00492,622,643,Thrombotic microangiopathy,Blood and lymphatic system,5,N,N,Drug interrupted,Recovered,N,0,N,0,N,Y,Y
AE0008772,S00492,632,656,Neutropenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008773,S00492,553,575,Aspartate aminotransferase increased,Investigations,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008774,S00492,690,703,Bilirubin increased,Investigations,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0008775,S00492,23,50,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008776,S00492,372,379,Pyrexia,General disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008777,S00492,665,693,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008778,S00492,387,391,Infusion related reaction,"Injury, poisoning, procedural",3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0008779,S00492,378,405,Sepsis,Infections and infestations,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008780,S00493,1,8,Cytokine release syndrome,Immune system disorders,4,Y,Y,Tocilizumab,Recovered with sequelae,Y,4,N,0,N,N,Y
AE0008781,S00493,13,29,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,2,N,Y,Corticosteroids,Recovered,N,0,Y,2,N,N,Y
AE0008782,S00493,692,702,Bilirubin increased,Investigations,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0008783,S00493,229,256,Aspartate aminotransferase increased,Investigations,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0008784,S00493,43,56,Tachycardia,Cardiac disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008785,S00493,422,447,Nausea,Gastrointestinal disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008786,S00493,462,472,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008787,S00493,675,704,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008788,S00493,691,699,Aphasia,Nervous system disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008789,S00493,491,496,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008790,S00493,583,585,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008791,S00493,215,226,Neutropenia,Blood and lymphatic system,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0008792,S00493,717,739,Anaemia,Blood and lymphatic system,3,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0008793,S00493,659,662,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008794,S00493,385,394,Nausea,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008795,S00493,200,204,Aphasia,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008796,S00493,114,116,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008797,S00493,430,456,Complement activation,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008798,S00493,465,484,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008799,S00493,265,270,Fatigue,General disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008800,S00493,587,604,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008801,S00493,61,87,Tachycardia,Cardiac disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008802,S00493,35,51,Tachycardia,Cardiac disorders,2,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0008803,S00493,148,175,Bilirubin increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008804,S00493,449,472,Hypogammaglobulinaemia,Immune system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008805,S00493,637,639,Aspartate aminotransferase increased,Investigations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008806,S00493,209,234,Cytomegalovirus infection,Infections and infestations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008807,S00493,100,115,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008808,S00493,679,681,Hypoxia,"Respiratory, thoracic, mediastinal",5,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0008809,S00494,291,298,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008810,S00494,337,363,Hypoxia,"Respiratory, thoracic, mediastinal",3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008811,S00494,50,76,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008812,S00494,256,272,Tachycardia,Cardiac disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008813,S00494,151,165,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008814,S00494,596,600,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0008815,S00494,660,676,Seizure,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008816,S00494,127,151,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0008817,S00494,431,458,Thrombocytopenia,Blood and lymphatic system,2,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0008818,S00494,57,69,Complement activation,Immune system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008819,S00494,672,677,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008820,S00494,36,60,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008821,S00494,652,672,Hypotension,Vascular disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0008822,S00494,625,636,Hypotension,Vascular disorders,3,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0008823,S00494,44,69,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0008824,S00494,233,259,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008825,S00494,512,522,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008826,S00494,473,492,Seizure,Nervous system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008827,S00495,2,14,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0008828,S00495,513,539,Alanine aminotransferase increased,Investigations,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008829,S00495,404,421,Sepsis,Infections and infestations,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0008830,S00495,68,80,Cytomegalovirus infection,Infections and infestations,3,Y,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008831,S00495,469,494,Confusional state,Psychiatric disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0008832,S00495,161,175,Neutropenia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008833,S00495,360,366,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008834,S00495,129,131,Thrombotic microangiopathy,Blood and lymphatic system,5,N,N,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0008835,S00495,525,535,Pyrexia,General disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0008836,S00495,605,632,Anaemia,Blood and lymphatic system,5,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0008837,S00495,370,371,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008838,S00495,115,140,Complement activation,Immune system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008839,S00495,618,641,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0008840,S00495,670,678,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008841,S00495,387,409,Fatigue,General disorders,1,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0008842,S00495,396,416,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0008843,S00495,131,136,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0008844,S00495,507,517,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008845,S00495,563,568,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008846,S00495,67,93,Anaemia,Blood and lymphatic system,4,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008847,S00495,25,49,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008848,S00495,720,740,Alanine aminotransferase increased,Investigations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008849,S00495,584,592,Pyrexia,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008850,S00495,330,338,Complement activation,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008851,S00495,466,494,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0008852,S00495,454,483,Alanine aminotransferase increased,Investigations,3,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0008853,S00495,689,717,Seizure,Nervous system disorders,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0008854,S00495,357,367,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008855,S00495,683,707,Sepsis,Infections and infestations,2,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0008856,S00495,639,655,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008857,S00495,71,80,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0008858,S00495,446,466,Sepsis,Infections and infestations,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008859,S00496,466,467,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0008860,S00496,584,586,Anaemia,Blood and lymphatic system,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0008861,S00496,114,140,Thrombocytopenia,Blood and lymphatic system,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0008862,S00496,331,358,Anaemia,Blood and lymphatic system,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0008863,S00496,719,731,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008864,S00496,8,11,Hypotension,Vascular disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008865,S00496,362,375,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008866,S00496,146,154,Anaemia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008867,S00496,458,474,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008868,S00496,542,543,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008869,S00496,544,545,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0008870,S00498,322,342,Neutropenia,Blood and lymphatic system,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0008871,S00498,144,161,Nausea,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008872,S00498,76,97,Aphasia,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008873,S00498,348,350,Aphasia,Nervous system disorders,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008874,S00498,24,34,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008875,S00498,576,588,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008876,S00498,650,676,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008877,S00498,162,191,Confusional state,Psychiatric disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0008878,S00498,702,708,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008879,S00498,280,298,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008880,S00498,139,142,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008881,S00499,276,295,Aphasia,Nervous system disorders,2,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0008882,S00499,192,194,Anaemia,Blood and lymphatic system,2,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0008883,S00499,601,623,Confusional state,Psychiatric disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008884,S00499,469,494,Sepsis,Infections and infestations,5,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008885,S00499,374,381,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008886,S00499,302,312,Bilirubin increased,Investigations,5,N,N,Hospitalization,Fatal,N,0,N,0,N,N,N
AE0008887,S00499,421,444,Hypotension,Vascular disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008888,S00499,536,558,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0008889,S00499,617,644,Seizure,Nervous system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008890,S00499,232,244,Confusional state,Psychiatric disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008891,S00499,654,657,Fatigue,General disorders,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0008892,S00499,262,289,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008893,S00499,539,568,Confusional state,Psychiatric disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008894,S00499,710,738,Aphasia,Nervous system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008895,S00499,475,483,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008896,S00499,181,193,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008897,S00499,113,116,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008898,S00499,145,157,Cytomegalovirus infection,Infections and infestations,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008899,S00500,44,49,Pyrexia,General disorders,3,Y,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0008900,S00500,548,562,Sepsis,Infections and infestations,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008901,S00500,654,682,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008902,S00500,438,441,Cough,"Respiratory, thoracic, mediastinal",3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0008903,S00500,37,65,Aphasia,Nervous system disorders,1,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0008904,S00500,153,179,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008905,S00500,470,474,Tremor,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008906,S00500,217,226,Pyrexia,General disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008907,S00500,365,367,Seizure,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008908,S00500,511,538,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008909,S00500,485,495,Seizure,Nervous system disorders,5,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008910,S00500,533,540,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008911,S00501,3,21,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0008912,S00501,6,12,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0008913,S00501,271,273,Tremor,Nervous system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008914,S00501,613,634,Bilirubin increased,Investigations,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0008915,S00501,484,502,Sepsis,Infections and infestations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008916,S00501,335,342,Fatigue,General disorders,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0008917,S00501,88,94,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008918,S00501,552,564,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008919,S00501,247,268,Anaemia,Blood and lymphatic system,4,N,Y,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0008920,S00501,401,429,Diarrhoea,Gastrointestinal disorders,2,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0008921,S00501,425,453,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008922,S00501,571,600,Bilirubin increased,Investigations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008923,S00501,428,451,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008924,S00501,485,486,Infusion related reaction,"Injury, poisoning, procedural",4,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0008925,S00501,510,523,Aphasia,Nervous system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008926,S00501,190,192,Bilirubin increased,Investigations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008927,S00501,62,72,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008928,S00501,681,687,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008929,S00501,559,586,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,None,Recovering,N,0,N,0,N,Y,Y
AE0008930,S00501,619,645,Mucosal inflammation,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008931,S00501,517,519,Aspartate aminotransferase increased,Investigations,1,N,N,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0008932,S00501,467,489,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008933,S00501,293,309,Seizure,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008934,S00502,521,522,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008935,S00502,43,69,Neutropenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008936,S00502,456,479,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0008937,S00502,224,235,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008938,S00502,707,736,Confusional state,Psychiatric disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0008939,S00502,397,409,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008940,S00502,623,627,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008941,S00502,298,314,Anaemia,Blood and lymphatic system,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0008942,S00502,589,609,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0008943,S00502,380,398,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0008944,S00502,471,497,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0008945,S00502,258,284,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008946,S00502,77,94,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0008947,S00502,681,693,Cough,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008948,S00502,364,376,Pyrexia,General disorders,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0008949,S00502,726,751,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008950,S00502,35,56,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008951,S00502,165,169,Nausea,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008952,S00502,477,499,Pyrexia,General disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008953,S00502,261,289,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008954,S00502,270,276,Seizure,Nervous system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008955,S00502,318,333,Tachycardia,Cardiac disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008956,S00502,179,195,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,Dose modification,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0008957,S00502,518,530,Tachycardia,Cardiac disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008958,S00502,711,740,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008959,S00502,546,553,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008960,S00502,16,28,Bilirubin increased,Investigations,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008961,S00502,19,35,Hypotension,Vascular disorders,2,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0008962,S00502,317,338,Aphasia,Nervous system disorders,3,N,N,Dose modification,Unknown,N,0,N,0,N,N,N
AE0008963,S00502,170,184,Hypotension,Vascular disorders,1,N,N,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0008964,S00503,5,20,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0008965,S00503,87,107,Vomiting,Gastrointestinal disorders,3,Y,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0008966,S00503,171,192,Hypotension,Vascular disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008967,S00503,446,452,Thrombocytopenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008968,S00503,720,746,Neutropenia,Blood and lymphatic system,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0008969,S00503,249,276,Aphasia,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008970,S00503,555,565,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Recovering,N,0,N,0,N,Y,Y
AE0008971,S00503,601,609,Diarrhoea,Gastrointestinal disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0008972,S00503,52,53,Tachycardia,Cardiac disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008973,S00503,259,264,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008974,S00503,244,269,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008975,S00503,375,390,Aphasia,Nervous system disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008976,S00503,622,645,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008977,S00503,680,690,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008978,S00503,289,314,Headache,Nervous system disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008979,S00503,554,561,Aphasia,Nervous system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0008980,S00503,59,82,Anaemia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008981,S00503,581,608,Neutropenia,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008982,S00503,68,96,Aspartate aminotransferase increased,Investigations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008983,S00503,452,462,Tachycardia,Cardiac disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0008984,S00503,246,249,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008985,S00503,33,37,Vomiting,Gastrointestinal disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0008986,S00503,718,740,Seizure,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0008987,S00503,130,140,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008988,S00503,418,444,Hypotension,Vascular disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008989,S00503,413,416,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0008990,S00503,72,95,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0008991,S00503,39,42,Complement activation,Immune system disorders,1,N,Y,Drug interrupted,Fatal,N,0,N,0,N,N,N
AE0008992,S00505,194,203,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0008993,S00505,22,48,Aspartate aminotransferase increased,Investigations,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0008994,S00505,705,728,Thrombotic microangiopathy,Blood and lymphatic system,3,Y,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0008995,S00505,626,631,Vomiting,Gastrointestinal disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0008996,S00505,411,427,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0008997,S00505,225,230,Sepsis,Infections and infestations,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0008998,S00505,92,100,Anaemia,Blood and lymphatic system,5,N,N,None,Recovering,N,0,N,0,N,N,N
AE0008999,S00505,454,483,Diarrhoea,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009000,S00505,432,434,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009001,S00505,368,372,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009002,S00505,29,35,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009003,S00505,393,400,Neutropenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009004,S00505,602,625,Sepsis,Infections and infestations,5,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009005,S00505,270,293,Complement activation,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009006,S00505,520,533,Aspartate aminotransferase increased,Investigations,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0009007,S00506,3,18,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0009008,S00506,559,563,Headache,Nervous system disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0009009,S00506,516,520,Cytomegalovirus infection,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009010,S00506,406,412,Complement activation,Immune system disorders,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0009011,S00506,728,741,Seizure,Nervous system disorders,3,Y,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009012,S00506,62,79,Complement activation,Immune system disorders,5,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009013,S00506,315,329,Neutropenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0009014,S00506,677,703,Thrombocytopenia,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009015,S00506,182,205,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009016,S00506,97,105,Aspartate aminotransferase increased,Investigations,3,Y,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009017,S00506,397,414,Cough,"Respiratory, thoracic, mediastinal",3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0009018,S00506,160,175,Anaemia,Blood and lymphatic system,3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009019,S00506,386,407,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009020,S00506,282,292,Hypotension,Vascular disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009021,S00506,234,242,Neutropenia,Blood and lymphatic system,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009022,S00506,0,1,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009023,S00506,669,674,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009024,S00506,238,254,Neutropenia,Blood and lymphatic system,1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0009025,S00506,164,183,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009026,S00506,43,64,Neutropenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009027,S00506,430,435,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,None,Fatal,N,0,N,0,N,Y,Y
AE0009028,S00506,225,248,Confusional state,Psychiatric disorders,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009029,S00506,482,497,Alanine aminotransferase increased,Investigations,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0009030,S00506,260,265,Thrombocytopenia,Blood and lymphatic system,2,N,N,None,Fatal,N,0,N,0,N,N,N
AE0009031,S00506,111,119,Fatigue,General disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009032,S00506,697,711,Sepsis,Infections and infestations,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009033,S00506,640,663,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009034,S00506,62,76,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0009035,S00507,390,418,Complement activation,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009036,S00507,348,366,Neutropenia,Blood and lymphatic system,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0009037,S00507,88,101,Aphasia,Nervous system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009038,S00507,467,496,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0009039,S00507,60,80,Fatigue,General disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009040,S00507,461,466,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009041,S00507,221,224,Seizure,Nervous system disorders,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009042,S00507,637,662,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009043,S00507,625,639,Headache,Nervous system disorders,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009044,S00507,360,366,Sepsis,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009045,S00507,519,521,Pyrexia,General disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009046,S00507,552,581,Tremor,Nervous system disorders,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0009047,S00507,149,157,Sepsis,Infections and infestations,4,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0009048,S00507,196,204,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009049,S00507,283,284,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009050,S00507,656,681,Aphasia,Nervous system disorders,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009051,S00507,149,154,Tachycardia,Cardiac disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0009052,S00507,606,619,Sepsis,Infections and infestations,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009053,S00507,314,332,Seizure,Nervous system disorders,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009054,S00507,622,634,Nausea,Gastrointestinal disorders,4,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009055,S00507,698,724,Vomiting,Gastrointestinal disorders,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0009056,S00507,188,213,Alanine aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009057,S00507,707,714,Complement activation,Immune system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009058,S00507,31,55,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009059,S00507,433,457,Complement activation,Immune system disorders,4,N,N,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0009060,S00508,6,24,Cytokine release syndrome,Immune system disorders,4,Y,Y,Tocilizumab,Recovered,Y,4,N,0,N,N,Y
AE0009061,S00508,463,485,Diarrhoea,Gastrointestinal disorders,2,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0009062,S00508,472,487,Bilirubin increased,Investigations,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009063,S00508,564,574,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009064,S00508,52,63,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009065,S00508,367,394,Diarrhoea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0009066,S00508,126,152,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0009067,S00508,140,147,Vomiting,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009068,S00508,583,586,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009069,S00508,140,155,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0009070,S00508,63,74,Fatigue,General disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009071,S00508,306,322,Alanine aminotransferase increased,Investigations,4,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009072,S00508,256,283,Aphasia,Nervous system disorders,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009073,S00508,447,461,Anaemia,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009074,S00508,4,24,Hypotension,Vascular disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0009075,S00508,340,362,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009076,S00508,258,261,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009077,S00508,583,598,Diarrhoea,Gastrointestinal disorders,4,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009078,S00508,368,374,Mucosal inflammation,Gastrointestinal disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009079,S00508,49,74,Alanine aminotransferase increased,Investigations,1,N,Y,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0009080,S00508,58,84,Seizure,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009081,S00508,34,48,Mucosal inflammation,Gastrointestinal disorders,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009082,S00508,552,559,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009083,S00508,579,584,Thrombocytopenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009084,S00508,676,704,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009085,S00508,7,8,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009086,S00508,308,333,Confusional state,Psychiatric disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009087,S00508,507,508,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009088,S00508,471,494,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009089,S00508,575,600,Pyrexia,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009090,S00508,566,579,Aspartate aminotransferase increased,Investigations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009091,S00508,421,429,Hypotension,Vascular disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009092,S00508,168,173,Thrombocytopenia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009093,S00508,726,753,Infusion related reaction,"Injury, poisoning, procedural",4,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0009094,S00509,451,466,Nausea,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009095,S00509,261,278,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009096,S00509,577,588,Headache,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009097,S00509,198,224,Bilirubin increased,Investigations,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009098,S00509,394,412,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009099,S00509,429,458,Neutropenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009100,S00509,588,599,Cough,"Respiratory, thoracic, mediastinal",4,N,N,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0009101,S00509,114,125,Complement activation,Immune system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009102,S00509,218,230,Tachycardia,Cardiac disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009103,S00509,2,18,Confusional state,Psychiatric disorders,2,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0009104,S00509,330,340,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009105,S00509,378,379,Pyrexia,General disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009106,S00509,423,439,Neutropenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009107,S00509,538,552,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0009108,S00509,37,50,Headache,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009109,S00509,315,341,Cytomegalovirus infection,Infections and infestations,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009110,S00509,486,488,Pyrexia,General disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009111,S00509,685,710,Aphasia,Nervous system disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0009112,S00510,358,361,Sepsis,Infections and infestations,5,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0009113,S00510,109,120,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009114,S00510,3,17,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009115,S00510,315,330,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009116,S00510,31,57,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009117,S00510,248,269,Anaemia,Blood and lymphatic system,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009118,S00510,106,110,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009119,S00510,521,541,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009120,S00510,246,259,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0009121,S00510,701,710,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009122,S00512,9,29,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,2,N,Y,Corticosteroids,Recovered,N,0,Y,2,N,N,Y
AE0009123,S00512,170,187,Aphasia,Nervous system disorders,3,Y,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009124,S00512,283,293,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009125,S00512,13,30,Hypotension,Vascular disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0009126,S00512,547,561,Pyrexia,General disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009127,S00512,446,459,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009128,S00512,365,382,Neutropenia,Blood and lymphatic system,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009129,S00512,717,724,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0009130,S00512,236,251,Aspartate aminotransferase increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009131,S00512,628,630,Alanine aminotransferase increased,Investigations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009132,S00512,446,447,Pyrexia,General disorders,2,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0009133,S00512,334,340,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,None,Not recovered,N,0,N,0,N,Y,Y
AE0009134,S00512,482,488,Complement activation,Immune system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009135,S00512,499,517,Aphasia,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009136,S00512,323,335,Pyrexia,General disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009137,S00512,725,738,Fatigue,General disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009138,S00512,569,598,Confusional state,Psychiatric disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0009139,S00512,711,739,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009140,S00512,607,610,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0009141,S00512,693,712,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009142,S00513,487,493,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009143,S00513,424,433,Seizure,Nervous system disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0009144,S00513,84,86,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009145,S00513,327,356,Mucosal inflammation,Gastrointestinal disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009146,S00513,580,586,Pyrexia,General disorders,2,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0009147,S00513,52,66,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0009148,S00513,482,511,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009149,S00513,59,74,Hypoxia,"Respiratory, thoracic, mediastinal",5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009150,S00513,288,293,Thrombocytopenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009151,S00513,41,57,Complement activation,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009152,S00513,698,722,Hypotension,Vascular disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009153,S00513,289,313,Tachycardia,Cardiac disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0009154,S00513,161,187,Confusional state,Psychiatric disorders,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0009155,S00513,308,319,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009156,S00513,418,436,Seizure,Nervous system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009157,S00514,524,525,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009158,S00514,577,594,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009159,S00514,485,514,Thrombocytopenia,Blood and lymphatic system,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009160,S00514,86,114,Tremor,Nervous system disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0009161,S00514,329,330,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009162,S00514,561,567,Anaemia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009163,S00514,312,329,Complement activation,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009164,S00514,457,475,Neutropenia,Blood and lymphatic system,4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009165,S00514,631,633,Pyrexia,General disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009166,S00514,254,263,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0009167,S00514,170,174,Fatigue,General disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0009168,S00514,48,60,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009169,S00514,493,500,Infusion related reaction,"Injury, poisoning, procedural",4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009170,S00514,632,650,Tremor,Nervous system disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009171,S00514,318,320,Sepsis,Infections and infestations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009172,S00514,457,471,Aspartate aminotransferase increased,Investigations,1,N,N,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0009173,S00514,496,511,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009174,S00514,470,493,Seizure,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009175,S00514,556,579,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009176,S00514,105,122,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009177,S00514,19,27,Hypotension,Vascular disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009178,S00515,647,659,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009179,S00515,207,230,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009180,S00515,158,175,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009181,S00515,687,707,Headache,Nervous system disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009182,S00515,173,178,Neutropenia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009183,S00515,262,280,Sepsis,Infections and infestations,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009184,S00515,599,622,Hypogammaglobulinaemia,Immune system disorders,4,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0009185,S00515,160,175,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009186,S00515,290,299,Nausea,Gastrointestinal disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009187,S00515,252,279,Mucosal inflammation,Gastrointestinal disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009188,S00515,511,525,Anaemia,Blood and lymphatic system,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0009189,S00515,376,404,Bilirubin increased,Investigations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009190,S00515,593,597,Diarrhoea,Gastrointestinal disorders,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009191,S00515,686,715,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009192,S00515,497,508,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009193,S00515,654,681,Cytomegalovirus infection,Infections and infestations,5,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009194,S00515,285,310,Tremor,Nervous system disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009195,S00515,49,75,Confusional state,Psychiatric disorders,2,N,Y,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0009196,S00515,37,56,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009197,S00516,500,516,Hypogammaglobulinaemia,Immune system disorders,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009198,S00516,204,211,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009199,S00516,240,259,Aphasia,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009200,S00516,282,290,Seizure,Nervous system disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009201,S00516,707,709,Complement activation,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009202,S00516,365,378,Sepsis,Infections and infestations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009203,S00516,132,161,Thrombocytopenia,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009204,S00516,179,208,Fatigue,General disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009205,S00516,6,24,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0009206,S00516,630,645,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009207,S00516,346,368,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009208,S00516,652,659,Seizure,Nervous system disorders,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009209,S00516,719,744,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009210,S00516,299,309,Confusional state,Psychiatric disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009211,S00516,630,644,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009212,S00517,508,518,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,Hospitalization,Recovered,N,0,N,0,N,Y,Y
AE0009213,S00517,35,37,Seizure,Nervous system disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009214,S00517,54,73,Alanine aminotransferase increased,Investigations,5,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009215,S00517,373,376,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009216,S00517,4,5,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009217,S00517,333,361,Alanine aminotransferase increased,Investigations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009218,S00517,140,151,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009219,S00517,255,261,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009220,S00517,233,248,Sepsis,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009221,S00517,180,195,Aspartate aminotransferase increased,Investigations,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0009222,S00517,372,393,Thrombocytopenia,Blood and lymphatic system,2,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0009223,S00517,355,366,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0009224,S00517,566,588,Pyrexia,General disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0009225,S00517,250,252,Tachycardia,Cardiac disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009226,S00517,471,486,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0009227,S00517,527,542,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0009228,S00517,495,512,Confusional state,Psychiatric disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009229,S00517,699,710,Confusional state,Psychiatric disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009230,S00517,101,115,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009231,S00517,202,217,Tremor,Nervous system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009232,S00517,496,511,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0009233,S00517,94,120,Aphasia,Nervous system disorders,3,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0009234,S00517,553,562,Vomiting,Gastrointestinal disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0009235,S00517,320,339,Hypogammaglobulinaemia,Immune system disorders,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009236,S00517,376,396,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009237,S00517,482,487,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009238,S00517,203,220,Sepsis,Infections and infestations,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009239,S00517,103,119,Pyrexia,General disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009240,S00517,85,100,Cytomegalovirus infection,Infections and infestations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009241,S00518,2,21,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0009242,S00518,8,20,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0009243,S00518,271,292,Headache,Nervous system disorders,3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009244,S00518,4,27,Hypogammaglobulinaemia,Immune system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009245,S00518,271,283,Pyrexia,General disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009246,S00518,291,299,Complement activation,Immune system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009247,S00518,570,584,Tremor,Nervous system disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009248,S00518,521,545,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009249,S00518,326,335,Anaemia,Blood and lymphatic system,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009250,S00518,24,49,Cytomegalovirus infection,Infections and infestations,3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009251,S00518,628,650,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0009252,S00518,455,469,Neutropenia,Blood and lymphatic system,1,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0009253,S00518,88,108,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009254,S00518,178,184,Complement activation,Immune system disorders,1,N,Y,Dose modification,Unknown,N,0,N,0,N,N,N
AE0009255,S00518,265,281,Bilirubin increased,Investigations,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009256,S00518,164,192,Alanine aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009257,S00518,108,127,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009258,S00518,479,484,Tremor,Nervous system disorders,1,N,N,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0009259,S00518,300,315,Thrombocytopenia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009260,S00518,522,541,Bilirubin increased,Investigations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009261,S00518,602,614,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009262,S00518,717,735,Nausea,Gastrointestinal disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009263,S00518,233,260,Nausea,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009264,S00518,289,306,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0009265,S00518,17,46,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0009266,S00518,489,511,Tachycardia,Cardiac disorders,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009267,S00518,420,426,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,Concomitant medication,Unknown,N,0,N,0,N,Y,Y
AE0009268,S00518,154,170,Hypotension,Vascular disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009269,S00518,65,93,Confusional state,Psychiatric disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009270,S00518,177,180,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009271,S00518,89,97,Confusional state,Psychiatric disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0009272,S00518,220,235,Diarrhoea,Gastrointestinal disorders,2,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0009273,S00518,676,700,Seizure,Nervous system disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009274,S00518,421,447,Fatigue,General disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009275,S00518,364,378,Bilirubin increased,Investigations,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009276,S00519,77,80,Seizure,Nervous system disorders,3,Y,Y,None,Recovering,N,0,N,0,N,N,N
AE0009277,S00519,477,493,Aphasia,Nervous system disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009278,S00519,372,390,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009279,S00519,389,406,Vomiting,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009280,S00519,256,260,Fatigue,General disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009281,S00519,14,30,Hypotension,Vascular disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0009282,S00519,544,555,Sepsis,Infections and infestations,3,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0009283,S00519,97,107,Thrombocytopenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009284,S00519,722,735,Thrombocytopenia,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009285,S00519,468,496,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009286,S00519,204,211,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009287,S00519,273,299,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0009288,S00519,607,634,Anaemia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009289,S00520,1,7,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0009290,S00520,433,439,Hypotension,Vascular disorders,3,Y,Y,None,Fatal,N,0,N,0,N,N,N
AE0009291,S00520,487,502,Diarrhoea,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009292,S00520,430,431,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009293,S00520,654,671,Complement activation,Immune system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009294,S00520,356,381,Tachycardia,Cardiac disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009295,S00520,557,576,Confusional state,Psychiatric disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009296,S00520,382,400,Fatigue,General disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009297,S00520,29,38,Sepsis,Infections and infestations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009298,S00520,497,513,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009299,S00520,583,605,Complement activation,Immune system disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009300,S00520,1,26,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009301,S00520,280,308,Alanine aminotransferase increased,Investigations,3,N,Y,None,Fatal,N,0,N,0,N,N,N
AE0009302,S00520,37,49,Alanine aminotransferase increased,Investigations,5,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009303,S00520,185,211,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009304,S00520,56,61,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009305,S00520,16,40,Neutropenia,Blood and lymphatic system,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009306,S00520,341,350,Nausea,Gastrointestinal disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009307,S00520,296,316,Cough,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009308,S00520,414,431,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009309,S00520,460,481,Aspartate aminotransferase increased,Investigations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009310,S00520,178,187,Thrombocytopenia,Blood and lymphatic system,2,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0009311,S00520,724,753,Fatigue,General disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0009312,S00520,253,265,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009313,S00520,566,580,Fatigue,General disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009314,S00520,461,465,Sepsis,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009315,S00520,95,122,Aspartate aminotransferase increased,Investigations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009316,S00520,127,147,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009317,S00520,63,81,Neutropenia,Blood and lymphatic system,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009318,S00520,513,516,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009319,S00520,613,621,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009320,S00521,673,690,Alanine aminotransferase increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009321,S00521,728,751,Tachycardia,Cardiac disorders,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0009322,S00521,154,179,Nausea,Gastrointestinal disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009323,S00521,225,238,Nausea,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009324,S00521,100,110,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009325,S00521,563,578,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009326,S00521,581,595,Sepsis,Infections and infestations,5,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0009327,S00521,629,650,Tremor,Nervous system disorders,2,N,N,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0009328,S00521,176,185,Bilirubin increased,Investigations,4,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009329,S00521,449,467,Confusional state,Psychiatric disorders,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0009330,S00521,258,260,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,Hospitalization,Recovered,N,0,N,0,N,Y,Y
AE0009331,S00521,235,242,Cytomegalovirus infection,Infections and infestations,3,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0009332,S00521,63,73,Diarrhoea,Gastrointestinal disorders,4,N,Y,Dose modification,Fatal,N,0,N,0,N,N,N
AE0009333,S00521,673,699,Hypotension,Vascular disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009334,S00521,705,713,Pyrexia,General disorders,1,N,N,Drug interrupted,Fatal,N,0,N,0,N,N,N
AE0009335,S00521,93,114,Cytomegalovirus infection,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009336,S00521,81,85,Pyrexia,General disorders,4,N,Y,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0009337,S00521,413,425,Cytomegalovirus infection,Infections and infestations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009338,S00521,81,99,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009339,S00521,501,529,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0009340,S00521,237,255,Vomiting,Gastrointestinal disorders,2,N,N,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0009341,S00521,495,501,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0009342,S00521,602,625,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009343,S00521,692,707,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009344,S00521,675,678,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0009345,S00521,370,378,Aphasia,Nervous system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009346,S00521,601,608,Aphasia,Nervous system disorders,5,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009347,S00522,177,184,Aphasia,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009348,S00522,422,443,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009349,S00522,664,678,Sepsis,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009350,S00522,382,399,Anaemia,Blood and lymphatic system,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009351,S00522,158,160,Nausea,Gastrointestinal disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009352,S00522,303,318,Thrombotic microangiopathy,Blood and lymphatic system,5,N,N,Dose modification,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0009353,S00522,500,507,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009354,S00522,320,347,Pyrexia,General disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009355,S00522,708,715,Headache,Nervous system disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009356,S00522,685,711,Pyrexia,General disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009357,S00522,344,353,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009358,S00522,27,49,Tremor,Nervous system disorders,2,N,N,None,Fatal,N,0,N,0,N,N,N
AE0009359,S00522,235,251,Confusional state,Psychiatric disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009360,S00522,52,77,Sepsis,Infections and infestations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009361,S00522,520,533,Infusion related reaction,"Injury, poisoning, procedural",3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009362,S00522,292,299,Tachycardia,Cardiac disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009363,S00522,611,621,Headache,Nervous system disorders,1,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0009364,S00522,298,324,Pyrexia,General disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009365,S00522,205,224,Sepsis,Infections and infestations,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009366,S00522,284,305,Cytomegalovirus infection,Infections and infestations,3,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0009367,S00522,517,537,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009368,S00524,619,648,Pyrexia,General disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009369,S00524,41,55,Thrombocytopenia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009370,S00524,702,718,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009371,S00524,353,368,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009372,S00524,171,174,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009373,S00524,156,168,Fatigue,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009374,S00524,38,39,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0009375,S00524,185,196,Pyrexia,General disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009376,S00524,693,698,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009377,S00524,15,27,Tachycardia,Cardiac disorders,1,N,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0009378,S00524,584,595,Sepsis,Infections and infestations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009379,S00524,436,439,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Not recovered,N,0,N,0,N,Y,Y
AE0009380,S00524,34,51,Headache,Nervous system disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0009381,S00524,727,750,Bilirubin increased,Investigations,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009382,S00524,242,269,Anaemia,Blood and lymphatic system,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0009383,S00525,462,472,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0009384,S00525,198,199,Seizure,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009385,S00525,273,298,Tachycardia,Cardiac disorders,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0009386,S00525,128,142,Hypoxia,"Respiratory, thoracic, mediastinal",3,Y,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009387,S00525,572,595,Tremor,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009388,S00525,222,239,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009389,S00525,493,505,Aspartate aminotransferase increased,Investigations,3,Y,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009390,S00525,617,642,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009391,S00525,179,181,Bilirubin increased,Investigations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009392,S00525,183,200,Hypotension,Vascular disorders,1,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0009393,S00525,8,18,Alanine aminotransferase increased,Investigations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009394,S00525,659,685,Seizure,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009395,S00525,578,586,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0009396,S00526,467,472,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009397,S00526,212,229,Bilirubin increased,Investigations,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0009398,S00526,554,565,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009399,S00526,387,392,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,Y,Y
AE0009400,S00526,382,396,Infusion related reaction,"Injury, poisoning, procedural",4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009401,S00526,536,539,Thrombotic microangiopathy,Blood and lymphatic system,4,N,Y,Drug interrupted,Recovered,N,0,N,0,N,Y,Y
AE0009402,S00526,445,451,Infusion related reaction,"Injury, poisoning, procedural",3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009403,S00526,262,282,Confusional state,Psychiatric disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009404,S00526,17,42,Seizure,Nervous system disorders,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009405,S00526,723,724,Thrombocytopenia,Blood and lymphatic system,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009406,S00526,10,36,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009407,S00526,392,400,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0009408,S00526,197,210,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0009409,S00526,81,102,Sepsis,Infections and infestations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009410,S00526,606,625,Confusional state,Psychiatric disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009411,S00526,706,708,Aphasia,Nervous system disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009412,S00526,52,72,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009413,S00526,116,126,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0009414,S00526,585,590,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009415,S00526,28,49,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009416,S00526,471,493,Tremor,Nervous system disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009417,S00526,409,424,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009418,S00526,659,679,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009419,S00527,317,340,Tremor,Nervous system disorders,3,Y,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0009420,S00527,643,659,Bilirubin increased,Investigations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009421,S00527,127,146,Alanine aminotransferase increased,Investigations,5,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0009422,S00527,627,652,Neutropenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009423,S00527,88,91,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009424,S00527,340,361,Complement activation,Immune system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009425,S00527,77,98,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009426,S00527,686,713,Thrombotic microangiopathy,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0009427,S00527,286,290,Diarrhoea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009428,S00527,395,408,Nausea,Gastrointestinal disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009429,S00527,149,173,Fatigue,General disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009430,S00527,480,481,Aspartate aminotransferase increased,Investigations,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009431,S00527,459,466,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009432,S00527,27,39,Complement activation,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009433,S00527,388,397,Diarrhoea,Gastrointestinal disorders,3,N,N,None,Fatal,N,0,N,0,N,N,N
AE0009434,S00527,359,372,Aphasia,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009435,S00527,614,618,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009436,S00527,421,435,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009437,S00527,463,480,Tachycardia,Cardiac disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009438,S00527,709,734,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009439,S00527,105,132,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009440,S00528,196,197,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009441,S00528,456,470,Cytomegalovirus infection,Infections and infestations,2,N,Y,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0009442,S00528,494,523,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0009443,S00528,583,599,Headache,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009444,S00528,103,129,Hypotension,Vascular disorders,1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0009445,S00528,72,96,Cytomegalovirus infection,Infections and infestations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009446,S00528,712,735,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009447,S00528,697,721,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009448,S00528,626,643,Bilirubin increased,Investigations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009449,S00528,457,469,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009450,S00528,289,316,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009451,S00528,243,253,Alanine aminotransferase increased,Investigations,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009452,S00528,370,396,Bilirubin increased,Investigations,4,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009453,S00528,35,48,Headache,Nervous system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009454,S00529,6,12,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0009455,S00529,517,538,Confusional state,Psychiatric disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009456,S00529,408,418,Infusion related reaction,"Injury, poisoning, procedural",3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009457,S00529,132,136,Sepsis,Infections and infestations,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0009458,S00529,662,682,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009459,S00529,471,473,Neutropenia,Blood and lymphatic system,5,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009460,S00529,147,153,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,None,Recovering,N,0,N,0,N,Y,Y
AE0009461,S00529,496,508,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009462,S00529,703,726,Fatigue,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009463,S00529,420,449,Fatigue,General disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0009464,S00529,601,616,Neutropenia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009465,S00529,171,197,Bilirubin increased,Investigations,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009466,S00529,313,324,Neutropenia,Blood and lymphatic system,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009467,S00529,619,629,Complement activation,Immune system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009468,S00529,80,87,Sepsis,Infections and infestations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009469,S00529,432,457,Anaemia,Blood and lymphatic system,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009470,S00529,493,510,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009471,S00529,325,347,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009472,S00529,474,486,Hypotension,Vascular disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009473,S00529,456,482,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009474,S00529,680,687,Confusional state,Psychiatric disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009475,S00529,589,597,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009476,S00529,397,425,Anaemia,Blood and lymphatic system,3,N,Y,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0009477,S00529,264,284,Complement activation,Immune system disorders,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009478,S00529,0,27,Pyrexia,General disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009479,S00529,253,258,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009480,S00529,360,372,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009481,S00529,681,687,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009482,S00529,729,743,Headache,Nervous system disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009483,S00529,215,218,Hypogammaglobulinaemia,Immune system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009484,S00530,421,431,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0009485,S00530,52,74,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0009486,S00530,176,195,Vomiting,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009487,S00530,19,27,Cytomegalovirus infection,Infections and infestations,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009488,S00530,9,27,Seizure,Nervous system disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009489,S00530,78,105,Complement activation,Immune system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009490,S00530,492,507,Tremor,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009491,S00530,426,450,Hypotension,Vascular disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009492,S00530,441,456,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009493,S00530,22,31,Bilirubin increased,Investigations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009494,S00530,167,193,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009495,S00530,273,291,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009496,S00530,74,90,Neutropenia,Blood and lymphatic system,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009497,S00530,416,419,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009498,S00530,137,144,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009499,S00531,7,14,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0009500,S00531,5,25,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,1,N,Y,Corticosteroids,Recovered,N,0,Y,1,N,N,Y
AE0009501,S00531,405,424,Complement activation,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009502,S00531,198,214,Sepsis,Infections and infestations,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009503,S00531,664,682,Tachycardia,Cardiac disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009504,S00531,195,218,Headache,Nervous system disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009505,S00531,713,734,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009506,S00531,273,297,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,None,Recovering,N,0,N,0,N,Y,Y
AE0009507,S00531,555,561,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0009508,S00531,205,231,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009509,S00531,628,632,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009510,S00531,251,268,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009511,S00531,506,520,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009512,S00531,7,26,Thrombocytopenia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009513,S00531,102,127,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009514,S00531,520,530,Thrombocytopenia,Blood and lymphatic system,2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009515,S00531,468,475,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009516,S00531,197,200,Headache,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009517,S00531,603,614,Anaemia,Blood and lymphatic system,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009518,S00531,473,497,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009519,S00531,639,651,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009520,S00531,169,171,Seizure,Nervous system disorders,5,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0009521,S00531,230,249,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009522,S00531,394,417,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009523,S00531,54,82,Aspartate aminotransferase increased,Investigations,2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0009524,S00531,148,169,Alanine aminotransferase increased,Investigations,3,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009525,S00531,199,214,Sepsis,Infections and infestations,3,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0009526,S00531,619,624,Complement activation,Immune system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009527,S00532,377,379,Seizure,Nervous system disorders,4,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009528,S00532,263,266,Aspartate aminotransferase increased,Investigations,3,Y,N,None,Not recovered,N,0,N,0,N,N,N
AE0009529,S00532,566,590,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009530,S00532,45,52,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009531,S00532,523,550,Alanine aminotransferase increased,Investigations,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009532,S00532,597,622,Thrombocytopenia,Blood and lymphatic system,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009533,S00532,276,302,Headache,Nervous system disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009534,S00532,651,680,Pyrexia,General disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009535,S00532,186,196,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009536,S00532,344,349,Cytomegalovirus infection,Infections and infestations,5,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009537,S00532,503,517,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Hospitalization,Recovered,N,0,N,0,N,Y,Y
AE0009538,S00532,599,619,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009539,S00532,431,459,Neutropenia,Blood and lymphatic system,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009540,S00532,678,703,Anaemia,Blood and lymphatic system,3,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0009541,S00532,412,441,Hypotension,Vascular disorders,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0009542,S00532,93,120,Neutropenia,Blood and lymphatic system,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009543,S00532,631,642,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009544,S00532,228,245,Complement activation,Immune system disorders,3,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0009545,S00532,100,111,Tachycardia,Cardiac disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009546,S00532,566,572,Hypogammaglobulinaemia,Immune system disorders,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009547,S00532,203,232,Tachycardia,Cardiac disorders,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009548,S00532,565,577,Tremor,Nervous system disorders,1,N,Y,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0009549,S00532,38,49,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009550,S00532,677,686,Sepsis,Infections and infestations,5,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0009551,S00532,639,665,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009552,S00532,88,99,Tremor,Nervous system disorders,2,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009553,S00532,429,434,Nausea,Gastrointestinal disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009554,S00532,670,689,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009555,S00532,519,525,Anaemia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009556,S00532,64,71,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Recovered,N,0,N,0,N,Y,Y
AE0009557,S00532,560,571,Fatigue,General disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009558,S00532,103,116,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009559,S00532,270,294,Fatigue,General disorders,3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009560,S00532,551,576,Confusional state,Psychiatric disorders,1,N,Y,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0009561,S00532,221,239,Tremor,Nervous system disorders,2,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009562,S00533,3,21,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009563,S00533,106,128,Nausea,Gastrointestinal disorders,1,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0009564,S00533,261,283,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009565,S00533,715,730,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,Concomitant medication,Not recovered,N,0,N,0,N,Y,Y
AE0009566,S00533,605,626,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009567,S00533,405,417,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009568,S00533,701,708,Seizure,Nervous system disorders,4,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0009569,S00533,142,167,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009570,S00533,286,308,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0009571,S00533,297,299,Bilirubin increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009572,S00533,81,89,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009573,S00533,271,272,Pyrexia,General disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009574,S00533,643,659,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0009575,S00533,443,445,Pyrexia,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009576,S00533,254,267,Pyrexia,General disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009577,S00534,1,20,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0009578,S00534,331,334,Seizure,Nervous system disorders,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0009579,S00534,54,80,Hypogammaglobulinaemia,Immune system disorders,3,Y,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009580,S00534,324,332,Cytomegalovirus infection,Infections and infestations,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009581,S00534,369,394,Tachycardia,Cardiac disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009582,S00534,425,434,Bilirubin increased,Investigations,5,Y,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009583,S00534,535,553,Pyrexia,General disorders,3,Y,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009584,S00534,577,589,Alanine aminotransferase increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009585,S00534,335,357,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009586,S00534,289,307,Bilirubin increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009587,S00534,373,396,Tachycardia,Cardiac disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009588,S00534,681,682,Tachycardia,Cardiac disorders,2,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0009589,S00534,695,698,Seizure,Nervous system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009590,S00534,250,254,Aphasia,Nervous system disorders,2,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0009591,S00534,391,396,Sepsis,Infections and infestations,5,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009592,S00534,609,624,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009593,S00534,491,508,Tremor,Nervous system disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009594,S00534,274,275,Thrombocytopenia,Blood and lymphatic system,1,N,N,Hospitalization,Fatal,N,0,N,0,N,N,N
AE0009595,S00534,86,114,Tremor,Nervous system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009596,S00534,720,749,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0009597,S00535,113,123,Headache,Nervous system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009598,S00535,45,48,Complement activation,Immune system disorders,5,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0009599,S00535,667,684,Anaemia,Blood and lymphatic system,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009600,S00535,126,132,Cytomegalovirus infection,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009601,S00535,320,344,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009602,S00535,469,492,Anaemia,Blood and lymphatic system,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009603,S00535,586,604,Thrombocytopenia,Blood and lymphatic system,5,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009604,S00535,333,334,Thrombotic microangiopathy,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0009605,S00536,337,340,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009606,S00536,291,308,Anaemia,Blood and lymphatic system,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009607,S00536,209,236,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009608,S00536,441,466,Cough,"Respiratory, thoracic, mediastinal",3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009609,S00536,318,333,Bilirubin increased,Investigations,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009610,S00536,290,316,Mucosal inflammation,Gastrointestinal disorders,5,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009611,S00536,32,49,Complement activation,Immune system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009612,S00536,321,328,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009613,S00536,104,128,Confusional state,Psychiatric disorders,3,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0009614,S00536,39,62,Headache,Nervous system disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009615,S00536,627,644,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009616,S00538,607,625,Hypogammaglobulinaemia,Immune system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009617,S00538,624,640,Fatigue,General disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009618,S00538,82,109,Tachycardia,Cardiac disorders,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0009619,S00538,663,675,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009620,S00538,553,561,Fatigue,General disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009621,S00538,692,698,Neutropenia,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009622,S00538,695,723,Fatigue,General disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009623,S00538,673,679,Headache,Nervous system disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009624,S00538,682,711,Neutropenia,Blood and lymphatic system,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009625,S00538,608,629,Tachycardia,Cardiac disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0009626,S00538,649,668,Complement activation,Immune system disorders,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0009627,S00538,657,663,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0009628,S00538,307,318,Alanine aminotransferase increased,Investigations,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009629,S00538,170,191,Confusional state,Psychiatric disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009630,S00538,82,88,Mucosal inflammation,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009631,S00538,437,440,Mucosal inflammation,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0009632,S00538,66,89,Cytomegalovirus infection,Infections and infestations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009633,S00540,3,6,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0009634,S00540,62,73,Thrombotic microangiopathy,Blood and lymphatic system,5,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0009635,S00540,205,228,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009636,S00540,218,247,Thrombocytopenia,Blood and lymphatic system,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009637,S00540,128,134,Aphasia,Nervous system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009638,S00540,338,349,Hypotension,Vascular disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009639,S00540,16,43,Tachycardia,Cardiac disorders,3,Y,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009640,S00540,577,582,Diarrhoea,Gastrointestinal disorders,3,Y,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009641,S00540,297,323,Bilirubin increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009642,S00540,556,559,Thrombocytopenia,Blood and lymphatic system,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009643,S00540,471,496,Complement activation,Immune system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009644,S00540,590,602,Tachycardia,Cardiac disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009645,S00540,707,732,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,None,Recovering,N,0,N,0,N,Y,Y
AE0009646,S00540,201,220,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009647,S00540,246,265,Tachycardia,Cardiac disorders,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0009648,S00540,643,661,Complement activation,Immune system disorders,3,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0009649,S00540,433,439,Sepsis,Infections and infestations,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009650,S00540,598,602,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009651,S00540,231,244,Aphasia,Nervous system disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009652,S00540,389,409,Aspartate aminotransferase increased,Investigations,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009653,S00540,167,196,Complement activation,Immune system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009654,S00540,80,93,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009655,S00540,587,592,Fatigue,General disorders,1,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0009656,S00540,253,260,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009657,S00540,197,213,Hypotension,Vascular disorders,5,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0009658,S00540,580,605,Vomiting,Gastrointestinal disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009659,S00540,421,447,Thrombotic microangiopathy,Blood and lymphatic system,2,N,Y,None,Recovering,N,0,N,0,N,Y,Y
AE0009660,S00540,706,735,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009661,S00540,182,202,Nausea,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009662,S00540,442,460,Hypotension,Vascular disorders,2,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009663,S00541,128,141,Aspartate aminotransferase increased,Investigations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009664,S00541,676,690,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009665,S00541,662,679,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009666,S00541,381,388,Aphasia,Nervous system disorders,3,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0009667,S00541,381,410,Aspartate aminotransferase increased,Investigations,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009668,S00541,507,525,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009669,S00541,293,307,Fatigue,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009670,S00541,266,272,Seizure,Nervous system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009671,S00541,307,309,Fatigue,General disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009672,S00541,213,239,Tachycardia,Cardiac disorders,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0009673,S00541,163,168,Confusional state,Psychiatric disorders,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009674,S00541,174,194,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009675,S00541,630,654,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0009676,S00541,655,670,Seizure,Nervous system disorders,5,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009677,S00541,629,641,Alanine aminotransferase increased,Investigations,1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0009678,S00541,614,643,Sepsis,Infections and infestations,4,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0009679,S00541,278,300,Neutropenia,Blood and lymphatic system,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0009680,S00541,41,68,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009681,S00541,706,722,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009682,S00542,469,473,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,None,Recovering,N,0,N,0,N,Y,Y
AE0009683,S00542,164,169,Hypotension,Vascular disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009684,S00542,201,224,Tremor,Nervous system disorders,1,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0009685,S00542,148,154,Neutropenia,Blood and lymphatic system,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009686,S00542,214,221,Complement activation,Immune system disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009687,S00542,721,729,Aspartate aminotransferase increased,Investigations,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009688,S00542,319,323,Alanine aminotransferase increased,Investigations,3,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009689,S00542,625,649,Aphasia,Nervous system disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009690,S00542,231,249,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009691,S00542,676,705,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0009692,S00542,417,442,Nausea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009693,S00542,447,474,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009694,S00542,568,596,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009695,S00542,43,48,Seizure,Nervous system disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009696,S00542,632,643,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0009697,S00542,535,555,Hypogammaglobulinaemia,Immune system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009698,S00542,333,335,Hypotension,Vascular disorders,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009699,S00542,359,386,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009700,S00542,28,50,Confusional state,Psychiatric disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009701,S00543,5,19,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0009702,S00543,9,15,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,3,Y,Y,Corticosteroids,Recovered,N,0,Y,3,N,N,Y
AE0009703,S00543,48,75,Thrombotic microangiopathy,Blood and lymphatic system,3,Y,N,Drug interrupted,Recovering,N,0,N,0,N,Y,Y
AE0009704,S00543,123,139,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009705,S00543,239,250,Tremor,Nervous system disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009706,S00543,229,231,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009707,S00543,2,3,Hypotension,Vascular disorders,3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009708,S00543,23,31,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009709,S00543,593,607,Infusion related reaction,"Injury, poisoning, procedural",2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009710,S00543,650,654,Headache,Nervous system disorders,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009711,S00543,461,466,Anaemia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009712,S00543,47,66,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009713,S00543,506,509,Thrombocytopenia,Blood and lymphatic system,3,N,Y,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0009714,S00543,6,25,Nausea,Gastrointestinal disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0009715,S00543,154,174,Neutropenia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009716,S00543,247,256,Anaemia,Blood and lymphatic system,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009717,S00543,255,274,Alanine aminotransferase increased,Investigations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009718,S00543,8,11,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009719,S00543,251,270,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009720,S00543,702,712,Confusional state,Psychiatric disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009721,S00543,657,672,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009722,S00544,375,388,Hypogammaglobulinaemia,Immune system disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009723,S00544,489,499,Aphasia,Nervous system disorders,5,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009724,S00544,591,609,Cytomegalovirus infection,Infections and infestations,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009725,S00544,25,46,Neutropenia,Blood and lymphatic system,4,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009726,S00544,213,234,Tremor,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009727,S00544,378,404,Confusional state,Psychiatric disorders,1,N,N,Dose modification,Recovered with sequelae,N,0,N,0,N,N,N
AE0009728,S00544,714,723,Aphasia,Nervous system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009729,S00544,70,85,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009730,S00544,489,512,Aphasia,Nervous system disorders,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0009731,S00544,322,324,Sepsis,Infections and infestations,4,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009732,S00544,241,250,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009733,S00544,219,236,Complement activation,Immune system disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009734,S00544,15,42,Diarrhoea,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009735,S00544,696,712,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,Hospitalization,Recovering,N,0,N,0,N,Y,Y
AE0009736,S00544,685,705,Vomiting,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009737,S00544,98,113,Confusional state,Psychiatric disorders,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0009738,S00545,681,682,Pyrexia,General disorders,3,Y,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0009739,S00545,461,483,Aspartate aminotransferase increased,Investigations,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009740,S00545,632,641,Alanine aminotransferase increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009741,S00545,240,265,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009742,S00545,10,39,Neutropenia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009743,S00545,260,289,Neutropenia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009744,S00545,318,344,Complement activation,Immune system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009745,S00546,50,58,Hepatocellular injury,Hepatobiliary disorders,4,Y,Y,Tocilizumab,Recovered with sequelae,Y,0,N,0,Y,N,Y
AE0009746,S00546,431,437,Vomiting,Gastrointestinal disorders,1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0009747,S00546,455,484,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009748,S00546,128,147,Complement activation,Immune system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009749,S00546,345,352,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0009750,S00546,675,691,Pyrexia,General disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009751,S00546,722,728,Tachycardia,Cardiac disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009752,S00546,547,558,Tremor,Nervous system disorders,1,N,Y,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0009753,S00546,634,653,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009754,S00546,388,404,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009755,S00546,193,209,Hypogammaglobulinaemia,Immune system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009756,S00546,0,17,Fatigue,General disorders,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0009757,S00547,370,389,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0009758,S00547,96,110,Fatigue,General disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009759,S00547,177,193,Sepsis,Infections and infestations,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009760,S00547,685,691,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0009761,S00547,684,694,Thrombocytopenia,Blood and lymphatic system,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009762,S00547,587,609,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009763,S00547,305,327,Pyrexia,General disorders,4,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009764,S00547,276,279,Vomiting,Gastrointestinal disorders,2,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0009765,S00547,354,364,Aphasia,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009766,S00547,623,651,Hypogammaglobulinaemia,Immune system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009767,S00547,380,400,Bilirubin increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009768,S00547,135,136,Hypotension,Vascular disorders,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009769,S00547,244,251,Headache,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009770,S00547,157,182,Fatigue,General disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009771,S00547,106,134,Complement activation,Immune system disorders,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009772,S00547,601,622,Headache,Nervous system disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009773,S00547,710,716,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0009774,S00547,374,401,Nausea,Gastrointestinal disorders,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0009775,S00547,249,270,Tremor,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009776,S00547,161,164,Headache,Nervous system disorders,1,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009777,S00548,577,581,Headache,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009778,S00548,277,289,Fatigue,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009779,S00548,328,336,Thrombocytopenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0009780,S00548,454,479,Diarrhoea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009781,S00548,398,422,Diarrhoea,Gastrointestinal disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009782,S00548,262,268,Nausea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009783,S00548,316,326,Diarrhoea,Gastrointestinal disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009784,S00549,5,7,Cytokine release syndrome,Immune system disorders,1,N,Y,Tocilizumab,Recovered,Y,1,N,0,N,N,Y
AE0009785,S00549,143,167,Headache,Nervous system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009786,S00549,497,525,Fatigue,General disorders,3,Y,Y,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0009787,S00549,370,396,Hypotension,Vascular disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009788,S00549,586,591,Tremor,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009789,S00549,79,97,Alanine aminotransferase increased,Investigations,4,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009790,S00549,310,330,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0009791,S00549,167,169,Neutropenia,Blood and lymphatic system,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009792,S00549,224,242,Bilirubin increased,Investigations,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009793,S00549,136,143,Complement activation,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009794,S00549,460,475,Aspartate aminotransferase increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009795,S00549,250,272,Complement activation,Immune system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009796,S00549,624,635,Anaemia,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009797,S00549,392,415,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Unknown,N,0,N,0,N,N,N
AE0009798,S00549,644,672,Sepsis,Infections and infestations,3,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009799,S00549,307,312,Anaemia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009800,S00549,119,132,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009801,S00549,682,701,Bilirubin increased,Investigations,2,N,N,Dose modification,Unknown,N,0,N,0,N,N,N
AE0009802,S00549,299,326,Pyrexia,General disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009803,S00549,618,621,Confusional state,Psychiatric disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009804,S00549,353,374,Cytomegalovirus infection,Infections and infestations,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009805,S00549,659,670,Cytomegalovirus infection,Infections and infestations,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009806,S00549,260,261,Anaemia,Blood and lymphatic system,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009807,S00549,532,544,Diarrhoea,Gastrointestinal disorders,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009808,S00549,164,168,Cytomegalovirus infection,Infections and infestations,2,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009809,S00549,34,52,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009810,S00549,178,189,Alanine aminotransferase increased,Investigations,4,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009811,S00549,698,699,Infusion related reaction,"Injury, poisoning, procedural",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009812,S00549,444,470,Diarrhoea,Gastrointestinal disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009813,S00549,246,264,Headache,Nervous system disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009814,S00549,681,701,Vomiting,Gastrointestinal disorders,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0009815,S00549,559,563,Neutropenia,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009816,S00549,681,697,Diarrhoea,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009817,S00550,588,611,Diarrhoea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0009818,S00550,88,93,Aspartate aminotransferase increased,Investigations,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0009819,S00550,24,41,Anaemia,Blood and lymphatic system,1,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0009820,S00550,637,660,Confusional state,Psychiatric disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009821,S00550,378,381,Headache,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009822,S00550,270,293,Pyrexia,General disorders,1,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009823,S00550,153,180,Tremor,Nervous system disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009824,S00550,207,225,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009825,S00550,15,37,Confusional state,Psychiatric disorders,3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009826,S00550,372,397,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009827,S00550,585,605,Sepsis,Infections and infestations,4,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0009828,S00551,559,573,Headache,Nervous system disorders,3,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009829,S00551,577,597,Tachycardia,Cardiac disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009830,S00551,14,28,Vomiting,Gastrointestinal disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009831,S00551,29,30,Hypogammaglobulinaemia,Immune system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009832,S00551,524,550,Cytomegalovirus infection,Infections and infestations,4,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0009833,S00551,715,729,Aphasia,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009834,S00551,574,600,Sepsis,Infections and infestations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009835,S00551,365,379,Thrombotic microangiopathy,Blood and lymphatic system,4,N,N,Hospitalization,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0009836,S00551,455,460,Tachycardia,Cardiac disorders,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009837,S00551,446,470,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009838,S00551,677,687,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,Y,Y
AE0009839,S00551,341,359,Cytomegalovirus infection,Infections and infestations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009840,S00551,164,190,Nausea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009841,S00551,387,402,Aphasia,Nervous system disorders,5,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0009842,S00551,187,193,Bilirubin increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009843,S00551,666,686,Aphasia,Nervous system disorders,4,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0009844,S00551,476,487,Alanine aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009845,S00554,1,16,Cytokine release syndrome,Immune system disorders,2,N,Y,Tocilizumab,Recovered,Y,2,N,0,N,N,Y
AE0009846,S00554,13,27,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,2,N,Y,Corticosteroids,Recovered,N,0,Y,2,N,N,Y
AE0009847,S00554,368,393,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009848,S00554,277,300,Vomiting,Gastrointestinal disorders,2,N,N,Hospitalization,Recovered with sequelae,N,0,N,0,N,N,N
AE0009849,S00554,405,426,Bilirubin increased,Investigations,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0009850,S00554,370,385,Tachycardia,Cardiac disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009851,S00554,230,254,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009852,S00554,118,141,Confusional state,Psychiatric disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009853,S00554,528,550,Cytomegalovirus infection,Infections and infestations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009854,S00554,537,553,Hypotension,Vascular disorders,5,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0009855,S00554,452,459,Complement activation,Immune system disorders,3,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0009856,S00554,513,537,Cough,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009857,S00554,323,326,Pyrexia,General disorders,1,N,N,None,Fatal,N,0,N,0,N,N,N
AE0009858,S00554,605,624,Hypoxia,"Respiratory, thoracic, mediastinal",5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009859,S00554,327,353,Thrombocytopenia,Blood and lymphatic system,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0009860,S00554,338,343,Confusional state,Psychiatric disorders,2,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0009861,S00554,319,339,Vomiting,Gastrointestinal disorders,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0009862,S00554,174,176,Bilirubin increased,Investigations,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009863,S00554,582,606,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,Y,Y
AE0009864,S00554,385,400,Anaemia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009865,S00554,597,611,Vomiting,Gastrointestinal disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009866,S00554,716,736,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009867,S00554,161,182,Sepsis,Infections and infestations,3,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009868,S00554,349,353,Seizure,Nervous system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009869,S00554,306,314,Vomiting,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009870,S00554,631,636,Nausea,Gastrointestinal disorders,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009871,S00554,419,438,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009872,S00554,13,28,Headache,Nervous system disorders,1,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0009873,S00554,193,205,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Concomitant medication,Recovered,N,0,N,0,N,Y,Y
AE0009874,S00554,267,281,Diarrhoea,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009875,S00554,526,550,Complement activation,Immune system disorders,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009876,S00554,165,184,Tachycardia,Cardiac disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0009877,S00554,301,324,Hypotension,Vascular disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009878,S00554,618,623,Tachycardia,Cardiac disorders,1,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0009879,S00554,483,501,Confusional state,Psychiatric disorders,3,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009880,S00554,192,207,Nausea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009881,S00554,174,193,Hypotension,Vascular disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009882,S00554,60,84,Cytomegalovirus infection,Infections and infestations,1,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0009883,S00554,77,83,Hypoxia,"Respiratory, thoracic, mediastinal",5,N,Y,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0009884,S00554,719,729,Hypoxia,"Respiratory, thoracic, mediastinal",4,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0009885,S00555,590,606,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009886,S00555,6,32,Hypotension,Vascular disorders,2,N,N,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0009887,S00555,313,326,Nausea,Gastrointestinal disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009888,S00555,16,17,Seizure,Nervous system disorders,5,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009889,S00555,245,259,Sepsis,Infections and infestations,5,N,N,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0009890,S00555,697,705,Bilirubin increased,Investigations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009891,S00555,598,610,Bilirubin increased,Investigations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009892,S00555,199,213,Complement activation,Immune system disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009893,S00555,172,187,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009894,S00555,471,484,Alanine aminotransferase increased,Investigations,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009895,S00555,434,438,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009896,S00555,168,191,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009897,S00556,184,208,Complement activation,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009898,S00556,122,150,Hypoxia,"Respiratory, thoracic, mediastinal",3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009899,S00556,278,288,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009900,S00556,9,14,Infusion related reaction,"Injury, poisoning, procedural",2,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009901,S00556,108,122,Cytomegalovirus infection,Infections and infestations,4,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009902,S00556,232,248,Bilirubin increased,Investigations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009903,S00556,413,420,Sepsis,Infections and infestations,5,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009904,S00556,347,366,Cytomegalovirus infection,Infections and infestations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009905,S00556,58,69,Diarrhoea,Gastrointestinal disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009906,S00556,707,727,Aphasia,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009907,S00556,432,458,Seizure,Nervous system disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009908,S00556,706,708,Tremor,Nervous system disorders,2,N,N,Dose modification,Recovered,N,0,N,0,N,N,N
AE0009909,S00556,266,284,Cytomegalovirus infection,Infections and infestations,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009910,S00556,617,636,Tremor,Nervous system disorders,3,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009911,S00556,640,649,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009912,S00556,636,638,Cytomegalovirus infection,Infections and infestations,4,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009913,S00556,290,315,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,None,Recovering,N,0,N,0,N,Y,Y
AE0009914,S00556,676,700,Cough,"Respiratory, thoracic, mediastinal",1,N,Y,None,Unknown,N,0,N,0,N,N,N
AE0009915,S00556,578,579,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0009916,S00557,536,548,Tachycardia,Cardiac disorders,2,N,N,Hospitalization,Recovering,N,0,N,0,N,N,N
AE0009917,S00557,442,462,Tachycardia,Cardiac disorders,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0009918,S00557,445,466,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,None,Recovered with sequelae,N,0,N,0,N,Y,Y
AE0009919,S00557,624,631,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009920,S00557,337,345,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0009921,S00557,667,671,Pyrexia,General disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009922,S00557,491,502,Mucosal inflammation,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009923,S00557,608,619,Aspartate aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009924,S00557,30,43,Anaemia,Blood and lymphatic system,3,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009925,S00557,705,710,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Drug interrupted,Unknown,N,0,N,0,N,N,N
AE0009926,S00557,102,104,Seizure,Nervous system disorders,3,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009927,S00557,708,716,Sepsis,Infections and infestations,3,N,N,None,Unknown,N,0,N,0,N,N,N
AE0009928,S00557,473,496,Headache,Nervous system disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009929,S00557,238,254,Confusional state,Psychiatric disorders,2,N,N,Hospitalization,Not recovered,N,0,N,0,N,N,N
AE0009930,S00557,141,163,Anaemia,Blood and lymphatic system,4,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009931,S00557,239,259,Tremor,Nervous system disorders,4,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0009932,S00557,196,208,Diarrhoea,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009933,S00557,510,521,Sepsis,Infections and infestations,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009934,S00558,4,8,Complement activation,Immune system disorders,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009935,S00558,512,514,Cytomegalovirus infection,Infections and infestations,1,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0009936,S00558,386,389,Vomiting,Gastrointestinal disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009937,S00558,600,604,Thrombotic microangiopathy,Blood and lymphatic system,5,N,Y,Drug interrupted,Recovered,N,0,N,0,N,Y,Y
AE0009938,S00558,373,401,Vomiting,Gastrointestinal disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0009939,S00558,549,576,Headache,Nervous system disorders,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009940,S00558,58,64,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009941,S00558,9,20,Diarrhoea,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0009942,S00558,69,76,Tachycardia,Cardiac disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0009943,S00558,648,659,Seizure,Nervous system disorders,5,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0009944,S00559,399,410,Aspartate aminotransferase increased,Investigations,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0009945,S00559,310,316,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009946,S00559,234,247,Aphasia,Nervous system disorders,5,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009947,S00559,344,352,Hypoxia,"Respiratory, thoracic, mediastinal",2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009948,S00559,115,125,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009949,S00559,136,154,Aspartate aminotransferase increased,Investigations,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009950,S00559,674,694,Tremor,Nervous system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009951,S00559,644,656,Neutropenia,Blood and lymphatic system,4,N,Y,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009952,S00559,76,87,Vomiting,Gastrointestinal disorders,2,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0009953,S00559,620,638,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0009954,S00559,655,665,Tremor,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009955,S00560,194,222,Aphasia,Nervous system disorders,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009956,S00560,450,451,Aspartate aminotransferase increased,Investigations,3,N,N,Hospitalization,Unknown,N,0,N,0,N,N,N
AE0009957,S00560,490,509,Headache,Nervous system disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009958,S00560,644,663,Hypotension,Vascular disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009959,S00560,365,393,Vomiting,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009960,S00560,374,379,Diarrhoea,Gastrointestinal disorders,1,N,Y,Hospitalization,Fatal,N,0,N,0,N,N,N
AE0009961,S00560,146,169,Alanine aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009962,S00560,18,37,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,None,Unknown,N,0,N,0,N,Y,Y
AE0009963,S00560,590,616,Diarrhoea,Gastrointestinal disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009964,S00560,139,155,Confusional state,Psychiatric disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009965,S00560,267,296,Aspartate aminotransferase increased,Investigations,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0009966,S00560,182,186,Seizure,Nervous system disorders,4,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009967,S00561,325,345,Seizure,Nervous system disorders,3,Y,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0009968,S00561,435,452,Diarrhoea,Gastrointestinal disorders,5,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0009969,S00561,62,72,Nausea,Gastrointestinal disorders,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0009970,S00561,103,105,Confusional state,Psychiatric disorders,2,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009971,S00561,678,704,Pyrexia,General disorders,2,N,Y,Drug interrupted,Fatal,N,0,N,0,N,N,N
AE0009972,S00561,706,732,Seizure,Nervous system disorders,3,Y,Y,Dose modification,Not recovered,N,0,N,0,N,N,N
AE0009973,S00561,565,571,Tachycardia,Cardiac disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009974,S00561,154,168,Cytomegalovirus infection,Infections and infestations,1,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0009975,S00561,311,323,Thrombotic microangiopathy,Blood and lymphatic system,1,N,N,None,Not recovered,N,0,N,0,N,Y,Y
AE0009976,S00562,555,583,Anaemia,Blood and lymphatic system,2,N,N,Dose modification,Unknown,N,0,N,0,N,N,N
AE0009977,S00562,711,731,Thrombotic microangiopathy,Blood and lymphatic system,3,Y,N,Hospitalization,Not recovered,N,0,N,0,N,Y,Y
AE0009978,S00562,209,232,Anaemia,Blood and lymphatic system,4,N,N,Drug interrupted,Recovered with sequelae,N,0,N,0,N,N,N
AE0009979,S00562,464,475,Hypotension,Vascular disorders,2,N,N,Concomitant medication,Not recovered,N,0,N,0,N,N,N
AE0009980,S00562,394,406,Bilirubin increased,Investigations,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0009981,S00562,636,660,Hypoxia,"Respiratory, thoracic, mediastinal",1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009982,S00562,243,254,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,Dose modification,Recovered,N,0,N,0,N,N,N
AE0009983,S00562,97,101,Seizure,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009984,S00562,34,49,Mucosal inflammation,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0009985,S00562,315,333,Fatigue,General disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009986,S00562,471,494,Anaemia,Blood and lymphatic system,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0009987,S00562,257,272,Cytomegalovirus infection,Infections and infestations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009988,S00562,481,497,Vomiting,Gastrointestinal disorders,1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0009989,S00562,153,170,Thrombocytopenia,Blood and lymphatic system,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009990,S00562,294,312,Fatigue,General disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009991,S00562,498,514,Hypotension,Vascular disorders,4,N,N,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0009992,S00562,388,397,Tachycardia,Cardiac disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009993,S00562,103,130,Aphasia,Nervous system disorders,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0009994,S00563,4,16,Immune effector cell-associated neurotoxicity syndrome,Nervous system disorders,3,Y,Y,Corticosteroids,Recovered,N,0,Y,3,N,N,Y
AE0009995,S00563,110,132,Aspartate aminotransferase increased,Investigations,3,Y,N,None,Recovered,N,0,N,0,N,N,N
AE0009996,S00563,581,608,Complement activation,Immune system disorders,1,N,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0009997,S00563,292,298,Tremor,Nervous system disorders,5,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0009998,S00563,589,596,Thrombocytopenia,Blood and lymphatic system,3,Y,Y,None,Recovered,N,0,N,0,N,N,N
AE0009999,S00563,339,351,Complement activation,Immune system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0010000,S00563,558,565,Headache,Nervous system disorders,3,Y,N,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0010001,S00563,346,358,Tachycardia,Cardiac disorders,3,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0010002,S00563,514,543,Aphasia,Nervous system disorders,1,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0010003,S00563,253,254,Complement activation,Immune system disorders,1,N,Y,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0010004,S00563,424,444,Neutropenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0010005,S00563,645,661,Thrombotic microangiopathy,Blood and lymphatic system,1,N,Y,Hospitalization,Recovering,N,0,N,0,N,Y,Y
AE0010006,S00563,203,232,Thrombotic microangiopathy,Blood and lymphatic system,3,N,N,None,Recovered,N,0,N,0,N,Y,Y
AE0010007,S00563,315,341,Complement activation,Immune system disorders,5,N,Y,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0010008,S00563,139,146,Nausea,Gastrointestinal disorders,2,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0010009,S00563,62,88,Tremor,Nervous system disorders,1,N,N,None,Recovering,N,0,N,0,N,N,N
AE0010010,S00563,99,100,Neutropenia,Blood and lymphatic system,2,N,Y,Concomitant medication,Unknown,N,0,N,0,N,N,N
AE0010011,S00563,192,193,Cough,"Respiratory, thoracic, mediastinal",1,N,N,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0010012,S00563,95,96,Hypogammaglobulinaemia,Immune system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0010013,S00563,85,101,Mucosal inflammation,Gastrointestinal disorders,3,N,Y,Dose modification,Recovering,N,0,N,0,N,N,N
AE0010014,S00563,719,735,Fatigue,General disorders,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0010015,S00563,169,180,Alanine aminotransferase increased,Investigations,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0010016,S00563,71,93,Infusion related reaction,"Injury, poisoning, procedural",1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0010017,S00563,652,665,Thrombocytopenia,Blood and lymphatic system,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0010018,S00563,8,14,Tachycardia,Cardiac disorders,2,N,Y,Drug interrupted,Recovering,N,0,N,0,N,N,N
AE0010019,S00563,629,636,Aspartate aminotransferase increased,Investigations,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0010020,S00563,289,299,Bilirubin increased,Investigations,2,N,N,Hospitalization,Recovered,N,0,N,0,N,N,N
AE0010021,S00563,555,576,Aphasia,Nervous system disorders,1,N,Y,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0010022,S00563,513,536,Aspartate aminotransferase increased,Investigations,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0010023,S00563,549,554,Aphasia,Nervous system disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0010024,S00563,54,78,Aphasia,Nervous system disorders,1,N,N,None,Not recovered,N,0,N,0,N,N,N
AE0010025,S00563,427,453,Tachycardia,Cardiac disorders,3,N,N,None,Recovered,N,0,N,0,N,N,N
AE0010026,S00563,421,440,Pyrexia,General disorders,2,N,Y,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0010027,S00563,473,501,Tremor,Nervous system disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0010028,S00563,638,666,Anaemia,Blood and lymphatic system,5,N,N,None,Recovered,N,0,N,0,N,N,N
AE0010029,S00563,495,512,Anaemia,Blood and lymphatic system,2,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0010030,S00563,497,518,Alanine aminotransferase increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0010031,S00563,468,492,Complement activation,Immune system disorders,2,N,Y,Concomitant medication,Fatal,N,0,N,0,N,N,N
AE0010032,S00564,1,11,Cytokine release syndrome,Immune system disorders,3,Y,Y,Tocilizumab,Recovered,Y,3,N,0,N,N,Y
AE0010033,S00564,717,727,Diarrhoea,Gastrointestinal disorders,1,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0010034,S00564,598,604,Cytomegalovirus infection,Infections and infestations,4,Y,N,Drug interrupted,Recovered,N,0,N,0,N,N,N
AE0010035,S00564,304,312,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0010036,S00564,207,225,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0010037,S00564,500,512,Bilirubin increased,Investigations,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0010038,S00564,699,700,Alanine aminotransferase increased,Investigations,1,N,N,None,Recovered with sequelae,N,0,N,0,N,N,N
AE0010039,S00564,590,602,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0010040,S00564,238,245,Mucosal inflammation,Gastrointestinal disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0010041,S00564,437,454,Aspartate aminotransferase increased,Investigations,1,N,N,Drug interrupted,Not recovered,N,0,N,0,N,N,N
AE0010042,S00564,177,205,Tachycardia,Cardiac disorders,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0010043,S00564,196,202,Cytomegalovirus infection,Infections and infestations,2,N,Y,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0010044,S00564,516,519,Bilirubin increased,Investigations,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0010045,S00564,340,345,Vomiting,Gastrointestinal disorders,3,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0010046,S00564,418,426,Sepsis,Infections and infestations,4,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0010047,S00564,459,481,Anaemia,Blood and lymphatic system,2,N,N,None,Unknown,N,0,N,0,N,N,N
AE0010048,S00564,665,666,Thrombocytopenia,Blood and lymphatic system,3,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0010049,S00564,163,189,Hypotension,Vascular disorders,2,N,Y,None,Recovering,N,0,N,0,N,N,N
AE0010050,S00564,310,324,Bilirubin increased,Investigations,2,N,N,None,Recovered,N,0,N,0,N,N,N
AE0010051,S00564,163,184,Vomiting,Gastrointestinal disorders,1,N,N,None,Recovered,N,0,N,0,N,N,N
AE0010052,S00564,331,340,Fatigue,General disorders,1,N,Y,None,Not recovered,N,0,N,0,N,N,N
AE0010053,S00564,29,56,Complement activation,Immune system disorders,2,N,N,Dose modification,Recovering,N,0,N,0,N,N,N
AE0010054,S00564,123,130,Anaemia,Blood and lymphatic system,3,N,N,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0010055,S00564,503,515,Headache,Nervous system disorders,1,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0010056,S00564,85,89,Cough,"Respiratory, thoracic, mediastinal",2,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N
AE0010057,S00564,250,262,Vomiting,Gastrointestinal disorders,2,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0010058,S00564,527,550,Seizure,Nervous system disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0010059,S00564,553,579,Tachycardia,Cardiac disorders,1,N,Y,Concomitant medication,Recovered,N,0,N,0,N,N,N
AE0010060,S00564,124,146,Aphasia,Nervous system disorders,2,N,N,Concomitant medication,Recovering,N,0,N,0,N,N,N
AE0010061,S00564,486,499,Neutropenia,Blood and lymphatic system,2,N,N,None,Recovering,N,0,N,0,N,N,N
AE0010062,S00564,506,534,Hypogammaglobulinaemia,Immune system disorders,4,N,Y,None,Recovered,N,0,N,0,N,N,N
AE0010063,S00564,477,501,Complement activation,Immune system disorders,1,N,Y,Concomitant medication,Recovered with sequelae,N,0,N,0,N,N,N