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[ "overall , neuropsychiatric symptoms in pd have been shown to be negatively associated with cognitive performance . although anxiety and depression are often related and coexist in pd patients , recent research suggests that anxiety rather than depression is the most prominent and prevalent mood disorder in pd [ 5 ...
research on the implications of anxiety in parkinson 's disease ( pd ) has been neglected despite its prevalence in nearly 50% of patients and its negative impact on quality of life . previous reports have noted that neuropsychiatric symptoms impair cognitive performance in pd patients ; however , to date , no study ha...
[ "as small non - coding rnas regulate gene expression and tumorigenesis , they may represent a novel cancer therapy . mirnas regulate a broad range of biological processes including timing of development , cell cycle progression , stem cell self - renewal , differentiation , cancer initiation , cancer cell prolifera...
small non - coding rnas include sirna , mirna , pirna and snorna . the involvement of mirnas in the regulation of mammary gland tumorigenesis has been widely studied while the role for other small non - coding rnas remains unclear . here we summarize the involvement of mirna in breast cancer onset and progression throu...
[ "the aim of the current study was to evaluate the role of the pigtail catheter drainage in outpatient management of patients with early onset severe ohss . in this study we established the efficacy and safety of pigtail catheter drainage in the management of severe / critical ohss in patients who underwent in vitro...
objective : to evaluate the efficacy and safety of outpatient management of severe ovarian hyperstimulation syndrome ( ohss ) requiring placement of a pigtail catheter.methods : retrospective analysis of thirty - three consecutive patients who underwent in - vitro fertilization ( 2003 - 2009 ) and developed severe / ...
[ "congenital adrenal hyperplasia ( cah ) refers to a group of autosomal recessive disorders caused by an enzyme deficiency which leads to defects in biosynthesis of steroid precursors . however , the non classical cah variant is more common with a prevalence rate of 1 in 1000 . depending on the severity and degree o...
congenital adrenal hyperplasia is a group of autosomal recessive disorders caused by enzyme deficiency which leads to defects in biosynthesis of steroid precursors . most common is 21 hydroxylase deficiency . clinical spectrum varies from non - classical cah to classic cah , and it may be simple virilising form or salt...
[ ", we hypothesized that pentoxifylline , due to its anti - inflammatory and immunosuppressive activity , may affect autoimmune diabetes . consequently , we decided to investigate whether pentoxifylline treatment could prevent the development of mlds - induced diabetes in mice . it has been shown that some drugs suc...
objective(s):pentoxifylline is an immunomodulatory and anti - inflammatory agent and is used in vascular disorders . it has been shown that pentoxifylline inhibits proinflammatory cytokines production . the purpose of this study was to investigate the therapeutic effects of pentoxifylline on the treatment of autoimmune...
[ "determinar a presena de anticorpos ige especficos para superantgenos estafiloccicos e o grau de sensibilizao mediada por esses , assim como se esses esto associados gravidade da asma em pacientes adultos .", "estudo transversal incluindo asmticos adultos em acompanhamento ambulatorial em um hospital universitri...
abstractobjective : to determine the presence of staphylococcal superantigen - specific ige antibodies and degree of ige - mediated sensitization , as well as whether or not those are associated with the severity of asthma in adult patients . methods : this was a cross - sectional study involving outpatients with asthm...
[ "the purpose of the study was to determine the effectiveness of nursing interventions based on family needs on family satisfaction level of hospitalized patients in the neurosurgery intensive care unit of al - zahra hospital in 2010 . the aim of this study was to analyze the satisfaction of the families of icu pati...
background : since the family is a social system , the impairment in each of its component members may disrupt the entire family system . one of the stress sources for families is accidents leading to hospitalization particularly in the intensive care unit ( icu ) . in many cases , the families needs in patient care ar...
[ "accordingly , the objective of the present study is to examine the impact of peplau therapeutic communication model on anxiety and depression in patients who were candidate for coronary bypass surgery . coronary artery disease is the most cardiovascular disorder as a health problem in developing and developed coun...
background and objective : anxiety and depression are among the psychological disorders in heart surgeries . establishing a simple communication is essential to reduce anxiety and depression . hence , the objective of the present studywas to examine the impact of peplau therapeutic communication model on anxiety an...
[ "antigenic analysis of select isolates was performed at the centers for disease control and prevention ( cdc ) in atlanta , georgia , by using the hemagglutination inhibition ( hi ) assay and postinfection ferret antisera ( 11 ) . sixty - four patients in nepal that met us department of defense enrollment criteria ...
worldwide emergence of variant viruses has prompted a change in the 20052006 h3n2 influenza a vaccine strain .
[ "the aim of this paper is to investigate differences in how obesity relates to indicators of physiological dysregulation in men and women of diverse populations . we examine how elevated weight and obesity ( using an indicator that considers both bmi and waist circumference ) relate to having levels defined as clin...
excess weight has generally been associated with adverse health outcomes ; however , the link between overweight and health outcomes may vary with socioeconomic , cultural , and epidemiological conditions . we examine associations of weight with indicators of biological risk in three nationally representative populatio...
[ "male macroprolactinomas ( mprl ) are usually revealed by headaches , visual troubles and gonadal insufficiency . however , in some very rare cases it can be a primary presentation or appear after radiotherapy or medical treatment used for tumors destroying the sellar floor and/or the skull base . our aim was to an...
background : suppurative meningitis ( sm ) or bacterial meningitis is a life - threatening condition , which is exceptionally due to pituitary tumors ( pt ) . our aim was to analyze its frequency among male macroprolactinomas ( mprl ) deemed to be aggressive , to report the cases we observed in our practice and describ...
[ "we report a series of 300 patients operated for lumbar dissectomy by destandau endospine system . many studies have not been reported in literature for lumbar discectomy by destandau endospine system .", "a total of 300 patients suffering from lumbar disc herniations were operated between january 2002 and decemb...
background : posterior endoscopic discectomy is an established method for treatment of lumbar disc herniation . many studies have not been reported in literature for lumbar discectomy by destandau endospine system . we report a series of 300 patients operated for lumbar dissectomy by destandau endospine system.material...
[ "this article will draw a conceptual model based on patients source of information , perceived benefits , perceived risks , and medical tourism destination image with available literature that will be helpful to mangers to draw their future course of action for competitive advantage and at the same time fulfill the...
background : role of information source , perceived benefits and risks , and destination image has significantly been examined in travel and tourism literature ; however , in medical tourism it is yet to be examined thoroughly . the concept discussed in this article is drawn form well established models in tourism lite...
[ "this review highlights three rtk signaling pathways involved in head and neck squamous cell carcinoma ; egfr , the type 1 insulin - like growth factor receptor ( igf-1r ) and the hepatocyte growth factor ( hgf ) receptor ( met ) . this short review will explore the relative contribution of each signaling axis to d...
molecular therapeutics for treating epidermal growth factor receptor-(egfr- ) expressing cancers are a specific method for treating cancers compared to general cell loss with standard cytotoxic therapeutics . however , the finding that resistance to such therapy is common in clinical trials now dampens the initial enth...
[ "the second set of cultures was treated with tq ( 0.01 , 0.1 , 1 , and 10 m ) on the eighth div for 4 consecutive days to investigate the effect of tq on the survival of dopaminergic neurons . cultures were treated with 1 m of tq ( a concentration that significantly protected dopaminergic neurons in mpp - treated c...
objectives : to investigate potential mechanisms mediating the neuroprotective effect of thymoquinone ( tq ) on dopaminergic neurons.methods:this study was conducted in the chemistry and biochemistry institute , university of veterinary medicine , vienna , austria between june and august 2013 . primary cultures were pr...
[ "non - union usually can definitely diagnosed within a year of fracture fixation with the same being achieved within 3 months at times . after non - union has been established , intervention is inevitable . we report a case of non - union of the fracture of the neck of the femur , who refused additional procedures...
fracture of the femoral neck continues to be a vexing clinical and therapeutic challenge for the orthopedic surgeon . the fracture has a propensity for non - union and avascular necrosis . it is a challenge for the orthopedic surgeon to decide when to intervene in a case with non - union where the implant continues to ...
[ "granuloma faciale ( gf ) is an uncommon , benign , inflammatory skin disorder of unknown etiology . we present a patient with multiple lesions of gf and its response to topical tacrolimus . the disease is notoriously resistant to therapies and often tends to relapse when treatment is discontinued . it is character...
granuloma faciale ( gf ) is a chronic condition characterized by red - brown plaques with follicular accentuation present usually on the face . we present a case of 35-year - old female with 5 year history of plaques over cheek and extra facial sites consistent with gf and its response to topical tacrolimus . this case...
[ "chronic myelomonocytic leukaemia ( cmmol ) is a rare disease with an incidence of 0.370.72 per 100 000 population . the median age at diagnosis varies between 65 years and 75 years [ 14 ] . the radical treatment is allogeneic stem cell transplantation , although this treatment is unsuitable for most patients becau...
we report a case of chronic myelomonocytic leukaemia ( cmmol ) in a 68-year - old man who developed osteomyelitis of the mandible . at the initial visit , he reported uncontrolled gingival bleeding , despite self - administered haemostasis . he complained of severe pain in the socket , despite potent opioid analgesia ....
[ "in a recent issue of critical care , we presented a series of 13 patients undergoing post - cardiotomy extracorporeal membrane oxygenation ( ecmo ) with bivalirudin - based anticoagulation . however , we think that a word of caution should be added to our recently published experience . owing to its pharmacologica...
bivalirudin has been proposed as the sole anticoagulant in patients under extracorporeal membrane oxygenation ( ecmo ) or cardiopulmonary bypass . owing to the pharmacodynamic properties of bivalirudin , areas of blood stagnation should be carefully avoided in order to limit the risk of thrombosis . the ecmo circuit ha...
[ "the purpose of this study was to assess lv ejection fraction ( lvef ) using 64-slice as a byproduct of mdct coronary examination and to compare efficacy of technique with 2d - tte in a heterogeneous patient population . also , review the role of mdct lv function with a relation to evolution in the technology of co...
background : coronary computed tomography angiography ( ccta ) is a frequently performed examination for coronary artery disease . when performed with retrospective gating , there is an opportunity to derive functional parameters of left ventricle utilizing automated software . complementary information , if validated ...
[ "therefore , it was our objective to assess the potential antimicrobial activity of aristolochia bracteolata using a bioassay - guided fractionation , in order to produce pure compound that can act as the lead compound in developing new , safe , and effective drug to replace the use of the harmful crude plant mater...
a bioassay - guided fractionation of methanol extract of aristolochia bracteolata whole plant was carried out in order to evaluate its antimicrobial activity and to identify the active compounds in this extract . antibacterial and antifungal activities of methanol extract against gram - positive , gram - negative , and...
[ "several infections , particularly infective endocarditis , have been reported to show positive findings on anca tests ; furthermore , their clinical features have been acknowledged to mimic anca - associated vasculitis , which may lead to a misdiagnosis and inappropriate treatment ( 2,3 ) . we herein report a pati...
we herein report an unusual case of an infected descending aortic pseudoaneurysm with luminal pathognomonic oscillating vegetation with serological findings and clinical features mimicking anti - proteinase 3-antineutrophil cytoplasmic antibody - associated vasculitis . the positive blood cultures and imaging findings ...
[ "we explored the relationship between vitamin d and endometriosis in a double - blind , randomized clinical trial looking at the effect of vitamin d supplementation on cessation of pain in proven endometriosis after laparoscopic diagnosis and treatment . endometriosis is a prevalent cause of infertility , pelvic pa...
backgroundendometriosis is a disabling disease of reproductive - age women . dysmenorrhea , dyspareunia , and pelvic pain are the main symptoms of endometriosis . its etiology is not clear . endometriosis may have various causes , including vitamin d deficiency , but its effect is controversial.material/methodsin this ...
[ "the aim of this study was to compare the apical sealing and gap formation of ah \n plus / gutta - percha with epiphany system . the null hypotheses tested were as follows : ( 1 ) there is no \n difference in apical microleakage or ( 2 ) apical gap formation among the experimental \n groups and ( 3 ) there is no co...
objectivethe aim of this study was to compare the correspondence between gap formation and apical microleakage in root canals filled with epoxy resin - based ( ah plus ) combined or not with resinous primer or with a dimethacrylate - based root canal sealer ( epiphany ) . material and methodsthirty - nine lower s...
[ "we report a case of pndm caused by a novel p.h186d heterozygous mutation in the kcnj11 gene whose treatment was successfully transitioned from insulin to oral sulfonylurea . encoding the sulfonylurea receptor 1 ( sur1 ) of atp - sensitive potassium ( katp ) channel , which has a key role in insulin secretion in gl...
permanent neonatal diabetes mellitus refers to diabetes that occurs before the age of 6 months and persists through life . it is a rare disorder affecting one in 0.2 - 0.5 million live births . mutations in the gene kcnj11 , encoding the subunit kir6.2 , and abcc8 , encoding sur1 of the atp - sensitive potassium ( katp...
[ ", we aimed to compare the plasma creatinine levels with spot urine il-18 levels following radiocontrast administration . recent studies have reported that urine levels of il-18 ( a pro - inflammatory cytokine ) , kidney injury molecule-1 , and neutrophil gelatinase - associated lipocalin ( ngal ) levels are import...
radiocontrast administration is an important cause of acute renal failure . in this study , compared the plasma creatinine levels with spot urine il-18 levels following radiocontrast administration . twenty patients ( 11 males , 9 females ) underwent radiocontrast diagnostic and therapeutic - enhanced examinations . th...
[ "given its high biocompatibility and well known safety profile and the anti - adhesive capabilities , ha and its composites represent an attractive , non - antibiotic , option to mitigate the impact of biofilm - related infections in various clinical settings including implant - related infections . aim of this rev...
living in biofilms is probably the most common condition for bacteria and fungi and biofilm - related infections account for the majority of bacterial infectious diseases worldwide.among others biofilm - related infections , those associated with implanted biomaterials have an enormous and still largely underestimated ...
[ "hence , this short term study was undertaken to detect the incidence of mdr , xdr , and pdr bacterial isolates in a tertiary care hospital of central india . in the last two decades , there were so much increase of infectious diseases that the standard of public health in many parts of the world is equivalent to ...
background and objective . antimicrobial resistance is now a major challenge to clinicians for treating patients . hence , this short term study was undertaken to detect the incidence of multidrug - resistant ( mdr ) , extensively drug - resistant ( xdr ) , and pandrug - resistant ( pdr ) bacterial isolates in a tertia...
[ "ureterocele is a congenital urinary abnormality characterized by the presence of an intrabladder hernia or cystic ballooning of the lower end of a ureter lying between the mucosa and muscle of the bladder . usg and voiding cystourethrography ( vcug ) are essential initial procedures for a child suspected of having...
ureterocele is a common ureteric anomaly detected in pediatric population . ureterocele diagnosis and evaluation need a variety of radiological methods . we report a case of 5-year - old female child sent for 99mtc - diethylene triamine pentaacetic acid scan for evaluation of glomerular filtration rate and excretory fu...
[ "therefore , this study evaluated the impact of vertebral fractures on the quality of life of healthy , community - dwelling women aged 65 years or older using the qualeffo . the assessment of hrqol has been used as a measure complementary to bone mineral density to evaluate and monitor the burden of osteoporosis o...
objectives : the aim of this study was to investigate the impact of asymptomatic vertebral fractures on the quality of life in older women as part of the sao paulo ageing & health study.methods:this study was a cross - sectional study with a random sample of 180 women 65 years of age or older with or without vertebral ...
[ ". however , the needs for admission and general anesthesia and their associated costs have made this option less favorable . in the outpatient setting , endometrial sampling is an effective and acceptable method for obtaining endometrial samples for histopathological assessment [ 3 , 4 ] . inadequate sampling is m...
aims . our aim is to compare the adequacy and diagnostic yield of samples obtained by the endometrial explora sampler i - mx120 with endometrial specimens obtained by conventional dilatation and curettage ( d&c ) . methods . a total of 1270 endometrial samples were received in the histopathology laboratories at the kin...
[ "the present paper aims to contribute basic sedimentological data from a barely studied region ( eirunep , 2.000 km sw manaus ; fig . we demonstrate that there is no evidence for a long - lived lake ( sensu gorthner , 1994 ) or any marine influx . conversely , we document a well - structured , aggrading fluvial s...
in miocene times a vast wetland existed in western amazonia . whereas the general development of this amazing ecosystem is well established , many questions remain open on sedimentary environments , stratigraphical correlations as well as its palaeogeographical configuration . several outcrops located in a barely studi...
[ "with increasing availability , widened indications , and technical refinements of computed tomography ( ct ) and magnetic resonance imaging ( mri ) , the number of incidentally discovered adrenal lesions , such as adrenal incidentalomas and incidental adrenal enlargement , is increasing . in a recent study by tang...
aim . to investigate incidental adrenal enlargement clinical characteristics and functional status and analyze functional lesion risk factors . materials and methods . this retrospective study included 578 patients with adrenal imaging features showing enlargement . incidental adrenal enlargement cases ( 78 ) were cons...
[ "we decided to transfer health knowledge to families through altering this information to childish poems and teaching children at kindergartens . in this method the outcome of transferring health knowledge through childish poems has been assessed in this study . the findings from studies in this field have encourag...
objectivethe purpose of this study is to propose an innovative method of knowledge transfer that aims to improve health literacy about pediatric infectious diseases prevention in families . children have an appreciable role in this scheme.methodsthis study is a before and after trial that has been conducted in hamedan ...
[ "septic arthritis of the shoulder is uncommon in adults . it is a surgical emergency as joint destruction occurs rapidly and can lead to significant morbidity and mortality .", "a 43 years old male came to our outpatient department with complaints of pain and stiffness of his left shoulder . on examination , his ...
introduction : septic arthritis of the shoulder is uncommon in adults . it is a surgical emergency as joint destruction occurs rapidly and can lead to significant morbidity and mortality . accurate diagnosis can be particularly challenging in patients with underlying liver disease . mri is a useful adjunct in early det...
[ "split - liver transplantation ( slt ) is an attractive alternative procedure to expand the donor pool in patients waiting for liver transplantation . we describe an uncommon late biliary complication that occurred after slt and was successfully treated by a multidisciplinary approach . the standard split - l...
biliary complications continue to be a major cause of morbidity after split - liver transplantation ( slt ) . in this report we describe an uncommon late biliary complication . one year after slt the patient showed an intrahepatic bile dicy dilatation with severe cholangitis episodes . the segmentary bile duct of hepat...
[ "this review will synthesize the data detailing the response of rr to ionizing radiation ( ir ) and will provide a perspective on the use of rr inhibitors as radiosensitizers in the treatment of human cancers . over the years , many groups have explored the use of rr inhibitors as chemotherapeutics in their own rig...
ribonucleotide reductase ( rr ) , the rate limiting enzyme in the synthesis and repair of dna , has been studied as a target for inhibition in the treatment of cancer for many years . while some researchers have focused on rr inhibitors as chemotherapeutic agents , particularly in hematologic malignancies , some of the...
[ "the study of long bones and the cells of the bone marrow is central to a myriad of research disciplines , including , but not limited to , bone biology , cancer biology , immunology , hematology , and biomechanics . all of these disorders represent active areas of research with the goal of identifying new preventa...
investigation of the bone and the bone marrow is critical in many research fields including basic bone biology , immunology , hematology , cancer metastasis , biomechanics , and stem cell biology . despite the importance of the bone in healthy and pathologic states , however , it is a largely under - researched organ d...
[ "tuberculosis ( tb ) is a major health issue in developing countries with over two billion people being infected with tuberculosis bacilli world wide ( 1 ) . although tb was recently regarded primarily as a disease of the developing countries it is now also on the increase in developed countries such as the united ...
tuberculosis ( tb ) is a major health issue in both developing and developed countries such as the uk . healthy individuals who contract the infection have only 5 - 10% chance of converting to the active disease over their lifetime . we present the clinical history of a 76 year old female who attended the emergency dep...
[ "the value of the ketogenic diet ( kd ) has been recognized in the treatment of epilepsy , although the exact mechanisms by which it exerts its effect remain an enigma . cancer cells need high levels of ros for the induction of angiogenesis and the production of tumor growth factors , thus , through this mechanism ...
although the ketogenic diet ( kd ) has been widely accepted as a legitimate and successful therapy for epilepsy and other neurological disorders , its mechanism of action remains an enigma . the use of the kd causes major metabolic changes . the most significant of them seems to be the situation of chronic ketosis , bu...
[ "the endotracheal tube ( ett ) should be placed at the optimal level to avoid inadvertent complication . the purpose of this study was to determine whether surface anatomical landmarks can be used to predict the mid - tracheal level in adult patients . although chest radiography and bronchoscopy are considered an a...
abstractendotracheal tube ( ett ) should be placed at the optimal level to avoid single lung ventilation or accidental extubation . this study was performed to estimate the mid - tracheal level by using surface anatomical landmarks in adult patients.neck computed tomography images of 329 adult patients between the ages...
[ "the relative novelty of these practices and roles , complicated by the pace of change in technical possibility and regulation , mean that there is still uncertainty about how to conceptualise embryo donation , not just in terms of systematic ethics but as a sociomoral practice in everyday social life and morality ...
this paper is based on linked qualitative studies of the donation of human embryos to stem cell research carried out in the united kingdom , switzerland , and china . all three studies used semi - structured interview protocols to allow an in - depth examination of donors and non - donors rationales for their donation ...
[ ", we discuss the etiology of pediatric mtc and currently available therapeutic modality for the cancer . sporadic mtc is very rare ; the vast majority of mtc diagnosed in the childhood is hereditary . the early onset of mtc in hereditary syndromes makes it an important endocrine disease that is increasingly manage...
medullary thyroid carcinoma ( mtc ) , which originates from thyroid parafollicular c cells , accounts for 3 to 5% of thyroid malignancies . mtc occurs either sporadically or in an inherited autosomal dominant manner . hereditary mtc occurs as a familial mtc or as a part of multiple endocrine neoplasia ( men ) type 2a a...
[ "this paper presents a complete 3d framework for updating multimodal preoperative images with respect to surgical brain deformations , due to brain shift and successive resections , followed and quantified using imr images . we take into account successive deformations based on a linear elastic biomechanical model ...
current neuronavigation systems can not adapt to changing intraoperative conditions over time . to overcome this limitation , we present an experimental end - to - end system capable of updating 3d preoperative images in the presence of brain shift and successive resections . the heart of our system is a nonrigid regis...
[ "has reviewed prospective studies investigating the possible protective effects of the dietary intake of n-3 pufa on prostate cancer development.16 fasano et al also has reviewed a lot of in vivo and in vitro experimental studies providing strong indications of the anti - tumor action of n-3 pufa against lung cance...
omega-3 polyunsaturated fatty acids ( n-3 pufas ) , particularly eicosapentanoic acid ( epa ) and docosahexanoic acid ( dha ) , has been acknowledged as essential very long - chain fatty acids contributing to either achieving optimal health or protection against diseases , and even longevity . recent high impact studie...
[ "individuals diagnosed with 46xy dsd show an overlap in clinical and biochemical parameters which emphasizes the need for comprehensive evaluation with a multidisciplinary approach . sexual development in males is a multistep process , implying a delicate network of molecular events that directs the bipotential gon...
background and objectives:46 xy disorders of sexual development ( dsd ) cover a wide spectrum of phenotypes ranging from unambiguous female genitalia to ambiguous male genitalia with hypospadias or dysgenetic gonads . management of these patients depends on the cause of dsd , degree of feminization , age at presentatio...
[ "herein , we chronologically assessed the source , patient demographics , and antimicrobial susceptibilities of mrsa - positive isolates from the hospital and community setting over a 5-year period in university hospital waterford a tertiary referral hospital with the primary microbiology laboratory for 4 acute ho...
abstracturinary tract infections are one of the most common infectious diseases diagnosed in the community and in the hospital setting . their treatment is complicated by drug - resistant pathogens and the colonization by microbes of indwelling urinary catheters . this study assessed the occurrence and antimicrobial su...
[ "acquired angioedema ( aae ) , an acquired deficiency of c1esterase inhibitor , is a medically treatable condition which can cause severe abdominal pain mimicking an acute surgical abdomen . this disorder is strongly associated with chronic lymphocytic leukemia ( cll ) and other indolent lymphoplasmacytic disorders...
introductionacquired angioedema ( aae ) , an acquired deficiency of c1esterase inhibitor , is a medically treatable condition which can cause severe abdominal pain mimicking an acute surgical abdomen . this disorder is strongly associated with chronic lymphocytic leukemia ( cll ) and other indolent lymphoplasmacytic di...
[ "", "", "distal clavicle fractures associated with partial and complete coracoclavicular ligament disruption are potentially unstable , and non - operative treatment of these fractures is associated with a high non - union rate.[13 ] partial ligament disruptions ( conoid or trapezoid ) retain some inherent stab...
purpose : distal clavicle fracture associated with complete coracoclavicular ligament disruption represents an unstable injury , and osteosynthesis is recommended . this study was performed ( 1 ) to retrospectively analyse the clinico - radiological outcomes of two internal fixation techniques , and ( 2 ) to identify a...
[ "results revealed a deep vein thrombosis in the common femoral vein as well as in the superficial femoral vein ( fig . acute or sub - acute inflammation was diagnosed given the perfusion image of soft tissue in the left hip area as well as the blood pool image ( fig . a 68-year - old woman visited the clinic with t...
a 68-year - old woman who suffered from polycythemia vera presented at our clinic with the chief complaints of pain , swelling , and a warm sensation in her left thigh . she had undergone a left bipolar hemiarthroplasty following a hip fracture 24 days prior to this presentation . her erythrocyte sedimentation rate and...
[ "brachial plexus surgery using the da vinci surgical robot is a new procedure . to evaluate the advantages and the restrictions of the technique , a cadaveric study of supraclavicular and axillary approaches was conducted . a wide experience in open brachial surgery of the brachial plexus , reported that lower brac...
brachial plexus surgery using the da vinci surgical robot is a new procedure . although the supraclavicular approach is a well known described and used procedure for robotic surgery , axillary approach was unknown for brachial plexus surgery . a cadaveric study was planned to evaluate the robotic axillary approach for ...
[ "therefore , the present study aimed to explore the concept of spirituality from the perspectives of iranian healthy elderly people . the central question of the paper was what characterizes the spirituality in the iranian healthy older people ? the main strengths of the present study are that it focuses on the sp...
background : spirituality is recognized as a personally important matter to the elderly , and there are evidences of its impact on their health . the aim of this study was to explore the concept of spirituality from the perspectives of iranian healthy elderly individuals.materials and methods : a conventional qualitati...
[ "two of them , catheter angiography and computed tomographic angiography ( cta ) , are based on the detection of contrast enhancement of cerebral vessels . in these examinations , , we performed a dynamic evaluation of contrast enhancement of the cerebral and extracranial arteries in patients with bd and control su...
introductionstasis filling , defined as delayed , weak , and persistent opacification of proximal segments of the cerebral arteries , is frequently found in brain dead patients . this phenomenon causes a major problem in the development of reliable computed tomographic angiography ( cta ) protocol in the diagnosis of b...
[ "gastric cancer is the second most frequent neoplasm of the alimentary tract after the large intestine . 5,103 people in poland were affected by it in 2008 . the case - to - death ratio of around 1 indicates unfavourable prognosis as to recovery from this disease [ 1 , 2 ] . the existence of gastric cancer metastas...
the typical symptoms of advanced cancer of the stomach are well known in clinical practice . the presented case concerns a patient with symptoms of left - sided renal colic , caused by a malignant tumour involving the ureter , which was diagnosed with a ct scan . the multifocal process , involving the stomach , two par...
[ "eosinophilic gastritis is an extremely rare disease that is characterized by eosinophilic infiltration of the various layers of the gastrointestinal tract in the absence of any definite causes of eosinophilia . the disease has to be distinguished from generalized eosinophilic disorder presenting with involvement o...
eosinophilic gastroenteritis is very rare disorder that is characterized by eosinophilic infiltration of the gastrointestinal tract in the absence of any definite causes of eosinophilia . it is associated with various clinical gastrointestinal manifestations , and depends on the involved layer and site . we report a ca...
[ "in this review , we discuss current knowledge of the expression , regulation , and function of caspase-14 . see introduction for details . since the cloning of caspase-14 in the late nineties , it has become clear that this protease is a unique member of the caspase family . the signaling cascades involved in epid...
caspase-14 is a unique member of the evolutionarily conserved family of cysteinyl aspartate specific proteinases , which are mainly involved in inflammation and apoptosis . however , recent evidence also implicates these proteases in proliferation and differentiation . although most caspases are ubiquitously expressed ...
[ "gossypiboma ( retained surgical sponge ) describes a mass of cotton or sponge that is left behind in the body cavity during a surgical operation . in fact , surgical sponges without opaque markers are the leading cause for the difficulty of a correct diagnosis . here , we present a case in which a foreign body , g...
gossypiboma is a term used to describe a foreign mass within the body that is composed of a cotton matrix . gossypiboma can cause infection or abscess formation from an early stage , or it can remain clinically silent for many years . gossypiboma can be diagnosed using several methods including abdominal x - ray films ...
[ "to demonstrate the usefulness of enhanced depth imaging optical coherence tomography ( edi - oct ) in investigating choroidal lesions inaccessible to ultrasound sonography .", "in a 60-year - old woman with an asymptomatic choroidal nevus , normal oct was used to observe the macula and edi - oct to image the cho...
purposeto demonstrate the usefulness of enhanced depth imaging optical coherence tomography ( edi - oct ) in investigating choroidal lesions inaccessible to ultrasound sonography.methodsin a 60-year - old woman with an asymptomatic choroidal nevus , normal oct was used to observe the macula and edi - oct to image the c...
[ "paradoxically , recent researches demonstrated the dark side of nrf2.4 cancer cells acquire a growth advantage by eliminating keap1-mediated negative control of nrf2 , which leads to activation of the nrf2-dependent defense response.4 constitutive upregulation of nrf2 has been found in many types of cancers , incl...
nuclear factor e2-related factor 2 ( nrf2 ) is a transcription factor that upregulates expression of a battery of genes to combat oxidative and electrophilic stress . modification of kelch - like ech - associated protein 1 ( keap1 ) by reactive oxygen species stabilizes nrf2 by escaping from degradation . nrf2 then bin...
[ "a 3-year - old male , known to have isolated speech delay , presented to the emergency department with severe body aches and inability to walk . few days prior to his presentation , the child started to have flu - like symptoms in the form of rhinorrhea and low - grade fever . the creatine kinase and serum transam...
rhabdomyolysis is an acute life - threatening condition that can occur in childhood secondary to many causes . the authors report the case of a 3-year - old male child who presented with acute rhabdomyolysis . the peak plasma creatine kinase level was extremely high . the 2 main causes of rhabdomyolysis in childhood ar...
[ "the donors were selected based on these inclusion criteria : myopic spherical refractive error ranging from 0.5 d to 10.00 d with no astigmatism or astigmatism less than 0.5 d ; healthy eyes free from significant systemic and ocular diseases ; and ability to understand the content of the consent form and willingne...
purpose : to describe the technique of cryopreservation of corneal lenticules extracted after small incision refractive lenticule extraction ( relex smile ) and initial results of femtosecond laser intrastromal lenticular implantation for hyperopia.methods:lenticules were collected from patients undergoing relex smile ...
[ "the purpose of the study was to compare the prognostic value of biomarkers and cytokines versus clinical severity scores and improved death risk prediction . . indicated that strem-1 was more accurate than pct and crp in the diagnosis of sepsis , but others showed that the prognostic utility of serum strem-1 in ...
objective . to investigate the prognostic significance of serum soluble triggering receptor expressed on myeloid cells-1 ( strem-1 ) , procalcitonin ( pct ) , n - terminal probrain natriuretic peptide ( nt - pro - bnp ) , c - reactive protein ( crp ) , cytokines , and clinical severity scores in patients with sepsis . ...
[ "the first tt in hot conditions ( tth-1 ) was not preceded by any outdoor riding in hot conditions ; tth-2 was preceded by 5 d in hot ambient conditions , and tth-3 was preceded by 13 d in the heat . the cyclists performed 3 tt in hot ambient conditions ( tth , see following section ) . nine male competitive cyclis...
abstractpurposethis study aimed to determine the effects of heat acclimatization on performance and pacing during outdoor cycling time trials ( tt , 43.4 km ) in the heat.methodsnine cyclists performed three tt in hot ambient conditions ( tth , approximately 37c ) on the first ( tth-1 ) , sixth ( tth-2 ) , and 14th ( t...
[ "luminous transmittance ( \n v ) , ir transmittance within the 7801400 nm range ( \n a ) , ir transmittance within the 7802000 nm range ( \n n ) , ir reflectance within the 7802000 nm range ( r \n n ) , ir absorptance within the 7802000 nm range ( a \n n ) , the level of protection ( shade number ) is determ...
the paper analyses the selected optical parameters of protective optic filters used for protection of the eyes against hazardous radiation within the visible ( vis ) and near infrared ( nir ) spectrum range . the indexes characterizing transmission and reflection of optic radiation incident on the filter are compared ....
[ "this retrospective observational study was conducted using electronic medical records from the south central veterans affairs health care network ( visn 16 ) , one of the largest of the 23 visns in the veterans health administration ( vha ) . dollars according to the medical care services component of the consumer...
objectivethis study compared the clinical and economic benefits associated with dual - goal achievement , glycated hemoglobin ( hba1c ) < 7% ( 53 mmol / mol ) and ldl cholesterol ( ldl - c ) < 100 mg / dl , with achievement of only the ldl - c goal or only the hba1c goal in veterans with type 2 diabetes mellitus ( t2dm...
[ ", we evaluated the feasibility of ultrasound in predicting difficult laryngoscopy in a chinese han population . due to the portable , noninvasive characteristics , point - of - care ultrasound ( us ) technique has been widely used in the operating room for ultrasound - guided nerve block , central venous access , ...
backgroundthe aim of this study was to determine if ultrasound ( us ) measurements of anterior neck soft tissue thickness at hyoid bone ( dshb ) , thyrohyoid membrane ( dsem ) , and anterior commissure ( dsac ) levels can be used to predict difficult laryngoscopy.material/methodswe included 203 patients age 2065 years ...
[ "", "w celu oceny wpywu perikardiotomii tylnej na wystpowanie wysiku osierdziowego , tamponady oraz migotania przedsionkw przeprowadzono prospektywne badanie kliniczne z randomizacj .", "badana grupa skadaa si z 96 pacjentw ( 77 mczyzn i 19 kobiet ) w wieku rednio 58,1 9,8 roku . i , n = 30 ) , grupy kontrolne...
introductionpericardial effusion and atrial fibrillation occur commonly after coronary artery surgery.aim of the studya prospective randomized clinical trial was conducted to evaluate the effects of posterior pericardiotomy on the occurrence of pericardial effusion , tamponade , and atrial fibrillation.material and met...
[ "this review therefore aims to serve as resource for health professionals to enhance their understanding of ototoxicity as well as their roles within an ototoxicity monitoring programme by providing an overview and description of this condition in patients diagnosed with cancer and receiving cisplatin chemotherapy ...
cisplatin is an effective drug used in the treatment of many cancers , yet its ototoxic potential places cancer patients , exposed to this drug , at risk of hearing loss , thus negatively impacting further on a patient 's quality of life . it is paramount for health care practitioners managing such patients to be aware...
[ "was then evaluated to determine the sequence specificity of the reaction , \n leading to the identification of proline as the optimal n - terminal \n amino acid . this mild bioconjugation reaction enables the facile , \n rapid modification of proteins to create a well - defined and stable \n linkage in a single po...
the synthetic modification of proteins plays an important role in chemical biology and biomaterials science . these fields provide a constant need for chemical tools that can introduce new functionality in specific locations on protein surfaces . in this work , an oxidative strategy is demonstrated for the ef...
[ "the present study was carried out to explore the dimensionality of this scale in an attempt to identify a set of underlying factors that exist and can explain the interrelationships among various manifestations of acute alcohol withdrawal symptoms . the knowledge of these underlying factors may enhance our underst...
objective . to identify the underlying factor structure of alcohol withdrawal syndrome , as measured with ciwa - ar . methods . exploratory factor analysis was conducted on the items of ciwa - ar . on 201 alcohol - dependent male patients seeking treatment for alcohol withdrawal at 36 hours of abstinence . results . a ...
[ "information regarding the amount of liquid intake expressed ( in litres , l ) and daily productivity output ( in tons ) were recorded . wet bulb globe temperature ( wbgt ) values during the 2007 harvest season at montelimar farm descriptive statistics were used to analyse climate data ( temperature ( c ) ; relativ...
backgroundheat illness is a major cause of preventable morbidity worldwide . workers exposed to intense heat can become unable to activate compensation mechanisms , putting their health at risk . heat stress also has a direct impact on production by causing poor task performance and it increases the possibility of work...
[ "we report an adult case of densely calcified , atypical cpp originated from the cpa without connection to the forth ventricle . choroid plexus papilloma ( cpp ) is a rare benign tumor accounting for 0.5% of all intracranial tumors that is more common in childhood , consisting of 1.5 to 6.4% of pediatric intracrani...
choroid plexus papilloma is a rare benign tumor accounting for 0.5% of all intracranial tumors . the majority of choroid plexus papillomas occur during the first 2 years of life in the ventricular system . moreover , dense calcification of the tumor is uncommon . we report an adult case of densely calcified , atypical ...
[ "we demonstrate cases from our current imaging system , where the measurements indicate corruption of the desired signals from multipath signals associated with the base of the tank . we then show experiments that allow us to partially isolate the effects to surface waves propagating along other pathways . we prese...
microwave imaging techniques are prone to signal corruption from unwanted multipath signals . near - field systems are especially vulnerable because signals can scatter and reflect from structural objects within or on the boundary of the imaging zone . these issues are further exacerbated when surface waves are generat...
[ "jaw cysts are usually painless , but they can increase in size as they absorb neighboring structures . it has been reported that marsupialization and decompression , both of which are conservative treatments that create an opening to reduce pressure within a cystic cavity and induce bone formation , generate few p...
objectivesthe purpose of this study is to evaluate the treatment efficacy of enucleation after decompression.materials and methodsa total of 17 patients with cystic lesion of the jaw were treated with decompression followed by enucleation . pre- and postdecompression panoramic radiographs were analyzed.resultsthe mean ...
[ "for the first time , the presented data suggest that a variant in the retn gene plays a significant role in acne pathogenesis . we also demonstrate an excess transmission of mutant allele g at retn-420 from 130 trio families using tdt analysis . therefore , we suggest that inherited variation in retn at -420 appea...
resistin ( retn ) , recently found to be relevant to inflammation and inflammatory disorders . we , therefore , aimed to investigate the potential role of retn gene polymorphism in pathogenesis of acne vulgaris with familial history . we investigated the retn-420c / g polymorphism in 180 patients with acne vulgaris and...
[ "this paper reports on the use of nmf in barbier - style reactions with a focus on rates of reaction , stereochemistry , and its use to form enediyne and epoxydiyne skeletal structures.(9 ) we were interested in examining what effect the increase in dielectric constant at lower temperature could have on a barbier -...
indium - promoted coupling reactions between propargyl aldehydes ( 1 ) and -chloropropargylphenyl sulfide are reported . although water has been shown to accelerate indium metal promoted reactions , the reverse pattern was observed in this series . use of n - methylformamide ( nmf ) , which has not previously been a so...
[ "the baicalin adjunctive therapy was tested in pediatric sepsis patients , after which the effect was compared based on the renal function assessment from bun and serum creatinine ( cr ) . this study aimed to uncover the effects of baicalin in treating aki in pediatric sepsis patients . we also performed experiment...
backgroundpediatric sepsis has high morbidity in children , may lead to acute kidney injury ( aki ) , and further aggravate the disease . baicalin is a kind of flavonoid in scutellaria baicalensis georgi and has been reported to protect against several diseases , but its roles in septic aki remain unclear . this study ...
[ "however , the effects of glycer - ages on other cancer cells remains poorly understood , and the molecular mechanisms behind their effects have not been clarified . in the present study , we examined the effects of glycer - ages on cultured human lung adenocarcinoma a549 cells and showed that glycer - ages en...
the receptor for advanced glycation end - products ( rages ) is associated with the malignancy of cancer . a recent study has suggested that glyceraldehyde - derived ages ( glycer - ages ) enhanced the malignancy of melanoma cells , but glucose - derived ages did not . however , the effects of glycer - ages on other ca...
[ "osseointegrated implants are a practical alternative to traditional prosthodontics ; however , designing an implant - supported prosthesis with function and esthetics is a challenge . the aim of the study was to demonstrate the accuracy and clinical precision of conventional surgical stent protocol for optimum ins...
aim : demand from implant patients for quality and efficient treatment is increasing . fortunately dental implant treatment is evolving with patients expectations.materials and methods : the study comprised of 45 patients for whom 89 implants were placed at different sites . efficacy of the stents is evaluated in deter...
[ "this study investigated a change of peripheral b - cell subsets in patients with t1d , lada , and t2d compared with healthy control subjects . the results show altered frequencies of various b - cell subsets associated with autoimmune diabetes . we hypothesized that an altered phenotype of b - cell subsets is asso...
objectiveb lymphocytes play an important role in the immunopathogenesis of autoimmune diabetes . we hypothesized that the altered b - cell subset phenotype is associated with autoimmune diabetes.research design and methodspatients with type 1 diabetes ( t1d ) ( n = 81 ) , latent autoimmune diabetes in adults ( lada ) (...
[ "therefore , we proposed to develop a comprehensive reserve on hpv with maximum possible inputs and outputs for the end users . ; however , it is not customized to explore for data analysis , host - pathogen interaction , strain - disease association , drug designing , and sequence analysis , etc . human papillomav...
human papillomavirus ( hpv ) infection is the leading cause of cancer mortality among women worldwide . the molecular understanding of hpv proteins has significant connotation for understanding their intrusion in the host and designing novel protein vaccines and anti - viral agents , etc . genomic , proteomic , structu...
[ "according to numerous estimations , 15% to 29% of patients with cataract have 1.5 diopters ( d ) of refractive astigmatism.1,2 cataract surgeons usually prefer to treat cataract and correct refractive ( spherical and astigmatic ) disorders at the time of the surgery . the aim of this study is to report the clinica...
purpose : to present clinical results of toric intraocular lens ( iol ) implantation for preexisting astigmatism correction and determine the time of any postoperative rotation.patients and methods : twenty - nine eyes of 19 patients underwent uncomplicated phacoemulsification and were implanted with an acrysof toric ...
[ "here , we test the gain change of ra projection neurons after exogenous nmda was applied to selectively activate nmda receptors , using whole - cell current clamp recording in adult male zebra finch slices . lman - ra synaptic transmission is necessary for the variability of song in adult zebra finch , suggesting ...
the song of zebra finch is stable in life after it was learned successfully . vocal plasticity is thought to be a motor exploration that can support continuous learning and optimization of performance . the activity of ra , an important pre - motor nucleus in songbird 's brain , influences the song directly . this vari...
[ ", we present a unique case of vascular pythiosis managed with limb - sparing vascular bypass grafts complicated by pseudoaneurysm formation . first described by veterinarians , pythiosis is a serious life- and limb - threatening infection endemic to thailand , but rarely seen in the western hemisphere . known to i...
introductionpythiosis is a serious life- and limb - threatening infection endemic to thailand , but rarely seen in the western hemisphere . here , we present a unique case of vascular pythiosis initially managed with limb - sparing vascular bypass grafts complicated by a pseudoaneurysm in our repair.presentation of cas...
[ "", "goterm cc = gene ontology cellular component , mf = molecular function , bp = biological process , and up_seq_feature = uniprot sequence feature . goterm cc = gene ontology cellular component , mf = molecular function , bp = biological process , and up_seq_feature = uniprot sequence feature ....
we evaluated a three - dimensional ( 3d ) human oral cell culture that consisted of two types of cells , oral keratinocytes and fibroblasts as a model of oral mucositis which is a debilitating adverse effect of chemotherapy and radiation treatment . the 3d cell culture model was irradiated with 12 or 2 gy , and total ...
[ "moreover , including biomarker outcomes can greatly improve the credibility and legitimacy of hiv prevention research . to address the issue of feasibility , we present two case studies of prevention trials with biomarker data collection among adolescents in kenya and zimbabwe . together these studies provide a va...
self - report of sexual behavior among adolescents is notoriously inconsistent , yet such measures are commonly used as outcomes for human immunodeficiency virus ( hiv ) prevention intervention trials . there has been a growing interest in the use of hiv and other sexually transmitted disease biomarkers as more valid m...
[ "stroke is rare in children , however , a common cause of neurological disease , and it is a major cause of death ranks in the top ten in pediatric period11,15 ) . documented incidence has been reported as 2.5 - 8/100000 children / year12,13 ) . however , if all medical treatment is fail to drop the intracranial pr...
objectivelife - threatening hemispheric stroke is associated with a high mortality and morbidity . decompressive hemicraniectomy has been regarded as an effective treatment option for refractory intracranial hypertension . here , we reported the clinical course of 5 children with decompressive craniectomy and duroplast...
[ "the primary objective was to assess albuminuria during different treatments compared with that with placebo ; secondary objectives were to assess effect on 24-h blood pressure , glomerular filtration rate ( gfr ) , biomarkers , and raas components . after washout , patients attended a randomization visit before 2 ...
objectivewe investigated whether the antiproteinuric effect of the direct renin inhibitor aliskiren is comparable to that of irbesartan and the effect of the combination.research design and methodsthis was a double - blind , randomized , crossover trial . after a 1-month washout period , 26 patients with type 2 diabete...
[ "this review summarizes recent data of effects by nano- and \n microstructured biomaterials and particles in vitro designed for \n orthopaedic application to get a solid \n framework outlining the critical interactions that govern the \n cytocompatibility . \n because biomaterials in orthopaedics are predominantly ...
cell - surface interactions play a crucial role for biomaterial application in orthopaedics . it is evident that not only the chemical composition of solid substances influence cellular adherence , migration , proliferation and differentiation but also the surface topography of a biomaterial . the progressive applica...
[ "six a17 bac and one fosmid library were used to create mt3.5 ( table s1 ) . five tissues were used for rna - seq analysis with ~10 million illumina 36 bp reads per library ( table s12 ) . most were processed by sanger paired - end sequencing of 3 - 6 kb shotgun libraries . three tissues were used for small rna ana...
legumes ( fabaceae or leguminosae ) are unique among cultivated plants for their ability to carry out endosymbiotic nitrogen fixation with rhizobial bacteria , a process that takes place in a specialized structure known as the nodule . legumes belong to one of the two main groups of eurosids , the fabidae , which inclu...
[ "surgical treatment of avascular necrosis ( avn ) of head of femur include core decompression , osteotomies , nonvascularized bone grafting , free vascularized fibular grafts , hip resurfacing , bipolar hip arthroplasty ( bha ) and total hip arthroplasty ( tha).123 tha is indicated in the young individual in avn wi...
background : bipolar hip arthroplasty ( bha ) is one of the options for treatment of avascular necrosis ( avn ) of the femoral head . acetabular erosion and groin pain are the most allowing for gross motion between the common complications . we propose that these complications are secondary to improper acetabular prepa...
[ "the success of valproic acid ( vpa , 2-propylpentanoic acid ) , a short branched chain fatty acid , for the therapy of absence seizures , partial seizures , tonic - clonic seizures , bipolar disorder , schizoaffective disorder , social phobias , neuropathic pain and for the prophylaxis and treatment of migraine he...
valproic acid ( vpa ) has successfully been used in the therapy of a number of conditions including absence seizures , partial seizures , tonic - clonic seizures , bipolar disorder , schizoaffective disorder , social phobias , neuropathic pain and migraine headaches . there is a high rise in number of cases of toxicity...
[ "antimicrobials have been used to treat mastitis for more than fifty years , but consensus about the most efficient , safe , and economical treatment is still lacking . the aim of this article is to review current treatments of mastitis during lactation and seek for evidence - based , best practice treatment recomm...
treatment of mastitis should be based on bacteriological diagnosis and take national and international guidelines on prudent use of antimicrobials into account . in acute mastitis , where bacteriological diagnosis is not available , treatment should be initiated based on herd data and personal experience . rapid bacter...
[ "this current belief stems both from epidemiological data and experimental studies that directly examine the potential for hiv transmission via arthropods ( lawrence 1987 ; lifson 1988 ; bockarie and paru 1996 ) approximately 40 million people are infected with the human immunodeficiency virus ( hiv ) worldwide ( u...
abstractmany pathogens of humans are blood borne , including hiv , malaria , hepatitis b and c , west nile virus , dengue , and other viral hemorrhagic fevers . although several of these pathogens are transmitted by blood - feeding arthropods , hiv is not . a number of properties of hiv and its life cycle have been ide...
[ "in the normal kidney , immunohistochemical expression of contractile protein alpha - smooth muscle actin ( asma ) is limited to the vascular smooth muscle cells . in pathological conditions , the expression of asma the first experimental publication on this subject , by johnson et al , involved a series of clinica...
summarybackgroundin a healthy kidney , contractile protein alpha - smooth muscle actin ( asma ) is immunohistochemically strongly expressed only in the blood vessels , while in pathological conditions it can be visualized in glomerular mesangial cells and interstitial myofibroblasts . the aim of this study was to explo...
[ "we report cytomorphology in two cases of chondroblastoma confirmed by histopathology with a brief review of literature . chondroblastoma accounts for < 1% of all primary bone tumors . usually occurring in young adolescents , however , unusual sites of presentation such as patella , talocalcaneal , and temporomandi...
chondroblastoma is a rare , giant cell - rich , benign neoplasm of bone . since the past few decades fine needle aspiration cytology ( fnac ) has gained momentum in preoperative diagnosis of bone lesions . at cytology , other giant cell - rich tumors and tumorlike lesions such as aneurysmal bone cyst ( abc ) , giant ce...
[ "suicide is a grave public health issue with a global mortality rate of 16 per 100,000 individuals.1 suicide is one of the top three leading causes of death , particularly among individuals aged 1544 years , which is a productive age group.1 suicide is a complex event that is influenced by biological , cultural , p...
backgroundsuicide is a grave public health issue that is responsible for a high mortality rate among individuals aged 1544 years . attitudes toward suicide among medical staff members have been associated with appropriate therapeutic responses to suicidal individuals . the aim of this study was to examine the effects o...
[ "the low adherence to guideline treatment recommendations has been reported in several studies.46 under or overprescription cause the inappropriate treatment of the disease.4,7 undertreatment of copd has also been reported in turkey.8 the bold study in adana , turkey showed that only 12.3% of the adults with copd u...
backgroundlow adherence to global initiative for chronic obstructive lung disease ( gold ) guideline recommendations has been reported worldwide . there has been no study on the adherence to gold guidelines for copd treatment in turkey.objectivesto investigate the rates of adherence to gold 2010 guidelines for copd tre...
[ "amphotericin b ( amb ) , an amphoteric polyene macrolide , has been considered one of the main options of antifungal therapy for serious and life - threatening mycotic infections for over 50 years despite the introduction of newer antifungal medications such as the azoles ( e.g. , voriconazole ) and echinocandins ...
backgroundnephrotoxicity is the most clinically significant adverse reaction of amphotericin b. different aspects of amphotericin b ( amb ) nephrotoxicity have not been studied well in our population.objectivesthe purpose of this study was to assess the frequency , time onset , and possible associated factors of amb ne...
[ "in the course of the years , n - glycan patterns of several snail species have been presented [ 1417 ] . methylated mannose and galactose residues were found to be frequent constituents . in the present study we determine the main o - glycan structures in snails and characterize a common core - trisaccharide . we ...
the glycosylation abilities of snails deserve attention , because snail species serve as intermediate hosts in the developmental cycles of some human and cattle parasites . in analogy to many other host - pathogen relations , the glycosylation of snail proteins may likewise contribute to these host - parasite interacti...