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3420 3421 3422 3423 3424 3425 3426 3427 3428 3429 3430 3431 3432 3433 3434 3435 3436 3437 3438 3439 3440 3441 3442 3443 3444 3445 3446 3447 3448 3449 3450 3451 3452 3453 3454 3455 3456 3457 3458 3459 3460 3461 3462 3463 3464 3465 3466 3467 3468 3469 3470 3471 3472 3473 3474 3475 3476 3477 3478 3479 3480 3481 3482 3483 3484 3485 3486 3487 3488 3489 3490 3491 3492 3493 3494 3495 3496 3497 3498 3499 3500 3501 3502 3503 3504 3505 3506 3507 3508 3509 3510 3511 3512 3513 3514 3515 3516 3517 3518 3519 3520 3521 3522 3523 3524 3525 3526 3527 3528 3529 3530 3531 3532 3533 3534 3535 3536 3537 3538 3539 3540 3541 3542 3543 3544 3545 3546 3547 3548 3549 3550 3551 3552 3553 3554 3555 3556 3557 3558 3559 3560 3561 3562 3563 3564 3565 3566 3567 3568 3569 3570 3571 3572 3573 3574 3575 3576 3577 3578 3579 3580 3581 3582 3583 3584 3585 3586 3587 3588 3589 3590 3591 3592 3593 3594 3595 3596 3597 3598 3599 3600 3601 3602 3603 3604 3605 3606 3607 3608 3609 3610 3611 3612 3613 3614 3615 3616 3617 3618 3619 3620 3621 3622 3623 3624 3625 3626 3627 3628 3629 3630 3631 3632 3633 3634 3635 3636 3637 3638 3639 3640 3641 3642 3643 3644 3645 3646 3647 3648 3649 3650 3651 3652 3653 3654 3655 3656 3657 3658 3659 3660 3661 3662 3663 3664 3665 3666 3667 3668 3669 3670 3671 3672 3673 3674 3675 3676 3677 3678 3679 3680 3681 3682 3683 3684 3685 3686 3687 3688 3689 3690 3691 3692 3693 3694 3695 3696 3697 3698 3699 3700 3701 3702 3703 3704 3705 3706 3707 3708 3709 3710 3711 3712 3713 3714 3715 3716 3717 3718 3719 3720 3721 3722 3723 3724 3725 3726 3727 3728 3729 3730 3731 3732 3733 3734 3735 3736 3737 3738 3739 3740 3741 | #version: 0.2 c c C C ( = cc c C c + ] CC C cc ccc N H N C O C n c CC CC ) ( C l cc cc O c N c ) [ - ] -] ) O CC C Oc ) (= ( [ n H ) = B r CC N +] ( C N c n CC CCC CC c C OC +] ) s c C O 1 2 n n N CC n cc C S CC OC +] (= 2 1 o c c nc C NC N Cc CCCC CCCC n nc CC OCC O Cc C n CC Oc CCC N C OCC CC NC S C ccc nc 2 3 3 2 CC O CS c CC S cc nc N S CCCC CC S i ccc s CC n C Nc N N cc n ] ( )= [ +] = S c c sc cccc n cn n CC Cc CCC O ccc o c s N CCC nc nc cc ncc S CC n o = [ n oc N NC n ccc N CCc O CCC nc n CCC NC )( [ OC O OCC O cn cc cc sc n cccc CCC Oc 3 4 4 3 CC l CS C CC Nc CCCC CCC CCCC N S Cc ccc n OCC OCC CCC n s ccc (= [ CO Cc F c +] ([ CCCC CCCCC CCC OC O CCCC o n CCC S C Br CCCCCCCC CCCCCCCC CC SC -] )[ CN S CCCC O ncc n CCCC c Cl c CCC Nc ncc s N O CO P c oc cc oc F C cnc n CCS c CS CC 5 4 COCC N ) - O P CCCC Oc CCCC NC 1 3 cc nn nn n nccc n -]) = cn ccc N CCCC CCS CC CO CCC N Nc nn nn O S s cc CCCCCCCC CCCC CCN S +] )( cn nc 4 5 CCC l CCCCCCCC CC cn ccn O N OCC OC O CCCO ncc nc OCC c o nc NCC NC nn nc CCCC OC o ccc 1 0 CS CCC N OC CCCCCCCC CCC N CCN OCC N OCC Oc N n 3 1 Br c CS Cc +]= [ CCCC n n s nc nn NCC Cc -] )( n sc cn nn O O OCC NC C F COCC NC NCC Oc CCCC S nnc n CO N c o CCCCC N OC OC OCCOCC OCCOCC cnc nc cs cn NCC n # [ CCC OCC NCC O COCC n 6 5 N CCCCC ] [ NCC S CCO P 1 1 -] #[ CCCCCCCC CCCCC C P nc sc S CCC CCCCCCCC CCCCCC CCCCC NC CCCC Cc O B COCC Oc Si H NCCC n no nc CC OCc CCCCC Oc NCC OC nn cc CC Br CCCCCCCC CCCCCCC C H CCC Sc N CCCN 2 4 ccnc n S e CCCCCCCC CCCCCCCCC 5 6 CCCCCCCCCCCCCCCC CC NCC Nc cnc s sc nc OCC n CCCC CCOc CO CCCNC COCC OC ns nc OCC CCC COCC O CCCN S cc on O CCCCCC CCCC l C I OCC Cc cs cc 4 2 CO CCCN CCC SC CO S nn sc -] =[ CCCC CCc s ccn ccc nn N OCC nc ncc O CCCCCCCC +] )= CN CC CCCC Nc NCCC OC O OC N OCc 7 6 CCO CCC N P s nc OCCC NC o cc S S 1 4 S n CO CCCC nnc s CCCC CCN NCC OCC N CCCCCC COCC c CCCCC O ] (= CCCCC OC COCC OCC N CCCO cn oc nc oc CCCCC n NCCC OCC S CCS COCC Nc Cl C +] )[ OCCC Oc CO NC ] ) s nnc CCCC CCNC NCCC NC CCCC OCC CCCCCCCC c CCCCCCCC Oc s n CCO CCCNC CCCCCCCCCCCCCCCC CCC -] )([ NCC SCc CS CCN ccn o nc on OCC S CC F ncc o 3 5 CCCCCCCCCCCCCCCC CCCCC NCC Sc O CCCCCCCCCCCC OCCC OC CCN CC cnc o 6 7 CC P CCO N OCCC n S CCN CCS Cc OO O B c N NS NCC OCCOCC CCC SCC COCC OCCOCC OCCOCCOCCOCC OCCOCCOCCOCC cs nn CCOCC Oc CCOCC N cc nnc COC Oc Cl Cc oc nc CCC Br NCCC Oc S CCCC CN N N CCNS CO CCCn CN NC CCCC CCCOc OCC Nc CCCC CCOC o ncc CCCC Sc CCS CCC O CCCN COC OC CCOCC OC 5 3 S CCCS O NC CCO S OCC OCCO CCCCC Nc O n CCCCCC Cc -] [ CCC OCc -] ( CCCCCCCC OC A s 8 7 CCOCC n NCC SC CCOCC O C B CS CCS 1 5 S OOO CCCC CCO I c cnn s S N CS CN CS SCC NCCC S CCOCC OCCOCC OCCC l CCCCCC n CCCCCCCC N O CCCCCCCCCC OCC Sc CCCCCCCCCCCCCCCC CCCC 6 4 nnc o OC n S CCOc s e OCCC S CCCCC l CCCO CCC CCCCCCCC CCOc CO CCCNc 4 1 B C CCC F Br C CO CCCOc CCCC NS CCCCCCCC CCCCOc OC N S CCc NC N CCCCC S Cl CC S CCNC ncn s S CCO CCCC CCCN S Sc CCCCCCCC Cc CCO CCCC 1 6 N NCC G e OC OCC OC Oc nn ccc CCCCCCCC CCCCc CCOCC OCC OCCOCC OC O CCCCCCC CCCCCCCC CCc OCCCC Oc CCO CCCN N CCCCc COCC NS NCC OCCO NCCC Nc cn sn CCO NC SCC SC COCC S CCOCC NC O CCCCCCCCC CCCCCCC OC P c OCC F CCCCCCCCCCCC OC T e +] [ 7 8 N CCCCCCC OCCCC O CS CCO CS CCNC OCCCC OC OCCC Nc CCCCCCCCCCCCCCCC CCCCCC S SC CN Cc OCCCC n OCCCC CCOc OCCOCC OCCOC COCC OCCNC nc no CCCCCCCC CCOC CCOC n CCCC SC CCCCCCCC NC +] # CCCCCCCCC OC CS CCCC 4 6 COC O I H ( # COCC CCC NCCCC n co cn CO O N Oc N NCc NCCC l A l 9 8 1 7 O CCCCCCCCCCCCCCCC CCCCCC Nc COCC Cc CCN Cc Br CC CCCC OCCCNC CCOCC c CCS S CCCC Br COCC OCCC NS c CCC P NCCCCC O OCC SC CCCO P OCC OCCC NCCC Sc CCO CCCn OCCCC CCOC OCCOCC Oc OCC NS NC l 2 5 CCCCCCCCC Oc cccc cc CCCC OCCC NCCCC CCNC OCC OCc N CCCCO N CCCCCCCC P C CC I CCCC CCCNC CCCCCCCCCCCCCCCC CCCCCCC c onc COC N OCCCC c OC F SS SS ] ([ CN n OCC Br CO B 1 8 Br Cc CCC OCCOC ] )( OCC CCCOc CO CCCS CCCCO P CCCCC Sc OO OO +] #[ CO n no cc COC n 3 7 co cc OCCOCC OCCO ] = CCCCCCCC n N CCCCN OC P CN CCS O CCCCCCCCCCC CCCC OCCOCC NCCCC Cc H g CCN N N CCCCNC S CCCCC CO OC OCCCC NC CCC SCc NCC F CCOCC S CCCCC NS CCCC OCc CCCCCCCCCCCCCCCC CCCCCCCC CCCO N CCCCCCCCCCCC CCOc N CCCCOc 7 5 NCCC OCc CCOCC Nc 5 2 OC NC NO S OCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOCCOCCOCCOCCOCC CCOCC OCCOCCOCCOCC 8 9 NC NC CCCCCCCCCCCCCCCC CCOC CCCCCCCCCCCCCCCC OC N SC OCCOCC OCCOCCO COCC OCc CCCCCCCC CCCCN CO NCc CCCC P CCCC CCOCC CCCCCCCC CCCCNC 1 9 CCC NCC S CCCc O CCCCN O Oc COCC OCCOC NCCCC CCO O F 5 1 CCCC CCS CCCCC Br CCCCCCCC CCCc NCCC OCCO 31 4 O CCCCCCCCCCCCCCCCCC COC OCC NCCOCCOCC NC cn sc CCCCCCCCCCCC CCOC S CCOC S CCCO ncnc n COCC OCCCC CS N OCCCC l NCCCN S B B CCCCCCCCCCCCCCCC CCCCCCCCCCCCCCCC ccn s S NC CCCCCCCC CCCOC NCC OCc CCO CCCNc CCCCCCCCCCCCCC Cc NCCCC SC 2 0 s ncc NCCCC l S CCCN CCCCC OCC CCCO S COCC OCCOc Cl CCc CS CCCNC CCCCCCCCCCCCCCCC CCCCCCCCC O OCC NC S CCCC SCC P P nnn s OC l CCCC OCCOc CCCCCC l CCCCCCCC CCN CS CCc CCCCCCC n S CCCCCC CCCCCCCC CCNC OC OCc CCCCCCCCCCCCCCCC CCNC CN CCC S P NCCC SC CO CCCOC I C NCCS CCCO CCS CCNC O CCCCCCCCCCCCCC NCC OCCOC N CCCCCCCCCCCC CN OC COCCOCCOCC OC CCC OCCOCC 10 9 CCCCCCCCCCCCCCCC Oc cc sn CCCCCCCCCCCCCCCC CCN OCCCC Cc COCC OCCOCCOCCOCC CCCCCCCC Nc NCCC OCCOC CS CCOc CCC I CCOCC OCCOC P H CCCCCCCCC N NC Oc NCCC OCCOCC CCCC OCCOC CS SC NCCCC OC CC B OCCC Sc 8 6 O Nc s sc -]) =[ CS CCn CCC OCCOc OCO P CCCCCCCCCCCCCCCC OCC ncc nn n scc NCC OCCC OCC l COCC Sc OCCCC CCO 5 7 - % O I NC O F CC CCS SCC S CN OCCC OCC OCCOCC OCCOc CCOCC OCCNC CCCCC SC OCCC Br COCCOCCOCC Oc CCS CCN S CCn OC S 3 6 CCCCCCCC S OCC CCCO CCCO CCCO OCCO P B N S CCCOc OC OCCOC OCCOCC OCC 2 2 CCOC Oc CCCCCCCCCCCC CCc CCOCC OCc CCCC CCCO CCCC CCSc OCCC F N OCCO cn ncc NCCC SCc CCCC OCCNC CS CCNc CCCCCCCC CCn CCCCCCCCCCCCCCCC CCOCC CCCCCCCCC NC CCN CCS NCCCC Nc F Cc 2 6 NCCCOCCOCC OCCCNC CCCCCCCCCCCC n CO CCCNS NC n CCCCCCCC O CO CCCCNC CCOC O CCCCCCCCCCCCCCC OC B OC N I S O S b S Nc CCCCCCCCCCCCCCCC CCOc NCC SCC CCC OCCO S H CS S CS CS NCCCCC NC 6 3 CCN CCC CCCCCCCCCCCCCCCC c CO CCCCOc OCCOCCOCCOCC OC CN CCN CCS CCNc OCC SCC CCOC OC CCCCCCCCCCCC S COCCO NC CCOC N OCCC OCc OCCCC S NN N CCCCCCCCCCCCC OC N OCCC S F CS CCCCC CCCCCCCCCCCC Cc CS P CCO O P b CCCCCCCC OCC CO CCCCCC CCCCCC SC CCCCCCC l CO Nc CCCCCCCCCCCCCCCC CCc CCCCCCCCC n CCCCO N OCCOCC NC OCCOCC OCCNC CCS CCCC CCOCCOCCOCC OCC OOOO OOOO COCC OCCCNC COCCC OCC N B CCCC B SSSS SSSS COCCOC Oc CN P CCCCCCCCCCCCCCCC CCCCCCCCCC CCCCCCCC CCS OCCO S CS CCCN B H NCCCCC OC CCC OCCc CN OCC O Sc S CCCCCCCC CCCC CCNS OCCCC CCc ] )[ CCCCCC Br S SCC CCC OCCN CS CCOC 6 2 CO CCCCn CCCCCCCCC O NCCCC CCN CCCCCCCC CCCOc CCCCCCCC CCCCO CCCCCCCCCCCCCCCC NC OO OC NCC OCCOCCOCCOCC CCC OCCNC OCCCC Nc Cl CCC OCC CCCOC CCCCC OCc 2 7 CCO CCCOc CCCCCCCCC OCC COC OCc CO OCC CS CCCNc SCC Nc CCCS CCC S OC S CCSc NC OC CCCCCCCC CCNc CCS Sc O NN NCC Br CCO CCCOC OCCO CCCC CCCCOCC Nc CN OCc CS CCCO CCO OC CCCCCCCCC S S Cl COC NC O p CCCCCCCC CCO OCCCC OCCCC OCCCCCCCC Oc CS CCSC CO NS CN Nc CCOCC NS 2 8 p H OCCOCCOCCOCC Oc NCCOCCOCC OC CCOCC OCCN CO CCCCN CCCCCC OCc CCCCCCC Nc CCCCO CCCN CCOCCOCCOCC OC CCCS P S Cn N OCCOc COCC OCOC CCS CCOc OCCOCCOCCOCC OCCO CCCCCCCC CCCNC CCCO CCCNC I n CCCC F OCC CCCN CCOC P COCC OCCN C Bc O CCCCCCCCCCCCC CO OCc CCCCCCCCCCCCCCCC N NCC OP CCCCCCCCCCCC SC 2 9 S I CCS CCCO 34 1 7 3 N CCCCCCCCCCC CS CCCCCC OB Oc NC P CO CCCO OCCO N CCCCCCCCCCCC OCC B i CS CCCCNC OCCC SCC COCCC OCCOc CCOCC Cc CCC NCCS OC I OCCCC OCC CCCCCCCCCCCCCCCC Cc S CCOCC cs nc CCCOCC n NCCC F OCCOCC N Cl CCCc 4 8 S CS OCCCC CCNC CCO CCCCNC CCS CCS COCC OCCCOc OCCCCCCCC CCOc CCOCCOCCOCC OCCNC O OCc 3 0 COC P OCCC SC o p OCC SS COCCC Sc 6 8 CCCC I CCCO CCCNc CCCC OCCCNc CCOCC OCCC CCCCCCCCCCCCCCCCC OC B CC N OCCc OCCCC Br N F S CCCn CCN NC OCCCO P 4 7 ] % CS CCCCNc COCC OCCO CS Sc CCCN N CS CCCn CCO CCCNS NN CCc CCCCCCCC CCCO CCCC OCCN CCO CCCl 6 1 G a OC Nc CO CCCCNc OCC SCc COCC OCCCOC CCCOCC Nc CCCCOCCOCC NC COCC SCC COCC CCCNC NCC OCCNC COCC OCCn CCCCCCC S O Br ] )= CCCO CCCC CCS P OCCCC CCN O SC 7 4 NC Nc Br CCC OCCCCCCCC OC COCCOCC Nc CCOCC OCCO CCCCCC P 1 32 +](= [ NCCS SCCNC CCCC OCCn CN O CS CCCOc CCCCCCCC Sc CCCCCCCCCCCCCCCC S S CCCOC s s CCS SC COCC OCCCNc p c CCN CCN CCOCC Sc CCCCCCC OCC COCCC OCCOC COO Sc I CC CO CCCCCCCCCCCCCCCCCC NCCOCCOCC OCCNC 3 12 CCC NCc COCC OCCOCCOCCOCCOCCOCCOCCOCC CCO n SC F CCCCCCCCC Br NCCCC OCCOC CCCCCCCCCCCC CCNC O NS NCCC Br Cl P CCO B CCS CCOC COCCOCCOCC OCC OCC CCCl CCS CCc CCCCO S NCCCCCC Nc 12 3 N CCCCCN O OP NS N N CCCCCCCCNC CCS SCCC S CSC OCC CCCNC S CCCCCCCCCCCC CCCC SCc CCCCC OP CCS CCn CCS CCCNc CCCCCCCCCCCCCCCC Nc OCCCCCCCC CCCOc 9 7 CN CCc CCCCC P CS CCCCCNC CCCCCCCCCCCC CCN CCCCC F CO CCCCc CCCCCCCC CCOCC OCCOCCOCCOCC OCCOCCO OC SC CNC l NCCCC OCC OCC P CCN P CO Oc CCOCC OCCOCCOCCOCCOCCOCCOCCOCC NCCOCCOCC OCCOCCC N CCCCCCCCCC O OS S CCCl CCCCCCCCCCCCCCCC CCCCCCCCCCCC CCCC OCCCCC NO P O NCC CCCCCCC Sc 3 3 3 8 F CCC COCC NCC CCCC CCOP COCCOCC OCCO t e CCS CCCOc OCCOCC OCCOCCC OCCCC CCS OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC O NCc P CC CO NCC CS NC NCCCCC SC Se H COCCOCC OCCC COCCOCCOCC OCCOC CCOCCOCCOCC NC CS CCCCCNc CCCCCCCC SC o ccn OC Br CCCCS CCC S CCNS S CCCCl CO CCCOCCC CCCCCCCC P NN NC O CCCNS CCOCC OCCOc NCCC OCCc OCCOCC OCCN N OCCCC CCCCC SCC COCC OCCc CCCCCCCCCCCCCCCC n NCCCC CCOC N Br S COC S CCCNC OCC I CN NN CCCO NC CS CCCCCCNC CCCCCCCC CCCS OCCC OCCOC CCOS OOO CCC B CS CCNS CCCCCCCC CCCn CCCCCCCCCCCC CCOCC B Cc N CCCCCCCCC O CCCCCCCCCCCCCCC -]) - COCC CCCNc CO CCCCCCCC OCO N OS OOO NCCOCC S CCCOCCCO CCCOCCCO OCC OCCCOC CCS CCCN NCCCCC l SS N CCCCC ON NN OC NCCCCC Nc 8 5 Cl CCN CCCCCCC OCc COCCOCC S COCCOCC OCc CCCC OCCCC CS COC COCC OCCCCNC COCCOCCOCC N 3 21 N CCCCCCCCCCCCCCCC S CCOP OCC CCCS OB c O ON CN CCCNC CO CCCCOC NCC OCCOCCOCCOCCOCCOCCOCCOCC CCO OCC CCS N OCCOCCOCCOCC OCCOC COCCOCCOCC OCCO B P N CCCCCCCCCCCCCCCCCC s cnn cn on CCCCCCCC OP CCOCC CCC CCOCCOCCOCC OCCC N OCCOC P N cc occ 31 5 NCCCCCCC l R u S CSc CCS CCCn SSSSSSSS SSSSSSSS CCN CCNCC NCC I CCCCCCCC CCSc COCC SC OCCCC Sc NCCOCC OCCC OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOCC 3 9 S CCCCCCCCCC OCC CCCn 21 3 CCCCCCCC CCCN CCS CCO CCCCCCCCCCCC Nc CP C NCCCO CCCl 8 4 S OCC OB O CCCCCCO CCCCc CCOC OCC NCC OCCCl CCCCCCCCCCCCCCCC CCn OP Oc NO N B O CN Sc CS CCCCCCNc CCOCC OCCNc OCCCC ON COCCOCCCC Nc OOOOOOOO OOOOOOOO Cl N -]) (= NCCCC Br OCCCCCC n OCCCCCCCC CCOC NCCCCCC SC cc ccccc CCCCCCCCCCCCCCCC CCCCCCCCCCC OCCCCC Br CCCCC OCCC CCCCCCCCCCCCCCCC CCCc COCCCC NS CCCCOCCOCC OCC CCO Nc SS S NCCCCCC l Cl CCCC NN CCC OCCCC CCOCC NCCCC I COCCOCC NS Ge H 5 8 F CCOc Br CCc CCN CCc OCCOCC S CCCCCCCCCCCC CCO OCCOCCOCCOCC OCCOc F N CCCO CCCNS CCCCCCCCCCCC Sc OCCCCCCCC CCCCOc OCCS SCC OCCCCCCC l CO CCCCCCOc ccnn n OCCCCCCCCC Oc N OCCCc CO CCCCCCCCCCCCCCCC CCO NCc NCCC I OCC CCCNc COC S SS SSC OCCSS CCOC C r O CCCCCCCCCCCCCCCCC CO Sc CO OS COCC OCCCn CCCO CCCN OCCCC CCCOc COCCC OCc BB BB 4 0 5 9 CCCCCCCC NS S OO ] =[ -] ([ CCS CCNS SS SC NCCOCC Br NCCCCCC Br CCCC CCOCCC CCCCC I CO CCCCCCCCCCCC CCOCC OCCOCCO OCCOCC n 10 8 COCCOCCOCC OCCOc S CO CCC OCCOCCOCCOCC CS CSC CCCCCCCC OCc CCCCCCCCCCCCCCCC CCCCCCCCCCCCCC OCCOC n CS SCCC CCCCCCCCC OP NCCCCC Br CP c CCOC S CCCOC n CCCCCCCCCCCCCCCC CCCCOC OCCCO N T l OCCCCCC Br NCCOCCOCC N NCCOCCOCC OCCC SCC F CCCCCCCCCCCCCCCC CCS CCOCCOCCOCCOCCOCC OCCOCCOCCNC S Oc S CCCCCCC OCC OCCCl CCCCCCC P OCCOCC Nc OCCOCC OCCC CCCCCCCCCC Br CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC NCC OCCN CS CCCc CS CCCNS NCCCCC I NCCCOCC Br N NCCO S nH CCCCCC I CCCS OOO NCCCCCC I OCCOCCO CCCC O CCCCCCCCCCCCCCCCCCCC CN CCNC NCC P CS OOO NCCCCC Oc SCCC Sc CCCCOCC NS NCCOCCOCC Nc 7 9 OC Sc CCCCC SCc CCCCCCCCCCCCCCCC CCOP NCCCC CCCNC CCCCCCCCCCCCC O OCCCCCCCC CCCOC CCOCCOCCOCC N CCOCCOCC OCCC CCO OCc NS CC CCCCCCCCCCCCCCCC O NCCCCCC n OCCCCCCCCCCCC OC CCN OC COC Nc NCC OCCOc CCCCCCCCC Nc NOC OC 4 32 S CCCCOc CS CCOCC COCCC SC CCCOCC OCc COCCO NCc SO ON I N CO OO CS Cn CS CCCS CCO CCCCCC OCCC P CCCCO CCCNS CCOCCOCCOCC Oc OCCCCOCCCC OCCCCOCCCC OCC NCC CS Nc CCOCC OCCn CCCCCCCCCCCCCCCC CCCCCCCCCCCCC NO O NCCCC CCc B n CS n CCCCCCCC CCSC CCCCCCCCCCCCCCCC SCC NCCCC NS OCCCO S OCCCCCCCC O CB C S CCCCN +] )=[ cccc ccccc COC OCCC CS CCCOC CCCN P CCCCCCC Br CCCCCCCCCCCC CCCO OCCCCCC l NCCOCCOCC OCC COCCOCCOCC NC F COc S CCCCCO nc nnc Br CCCC COC Sc CO CCCCCCCCC CS CO CCCCCCCC CCCCOP NCCCC OCc NCCN CC OCCS CCO OCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOCC OCCOCCO N S CCCCCCCCCCCCCCCC CCCC OCCc -] = CS SCc CS CCCCNS SCC l CCCCCCCCCCCCCCCC CCO S CCCCO nnc nc COCCC l CCCC OCCCn CO CCCCCCC CCS CCSCC CCCCO CCCCCC CCCCCCCCCCCC CCCOc 4 9 CCCS CCCC CCCCO NC OCCCCCC Cc COCCCC OCC CO CCCOP CS CNC CCCO CCCn CCCCCCCCCCCCCCCC OP CCCCCCCCCCCCCCCCC O COCCO NS 7 2 CCCC CCCOP CS CCCCCNS CCO NS CCCOCC OCCC COCCO CCCNS OCCCCCCCC CCO 4 4 S Br CCN n CCCCC OS CS OC CCS CCCOC NCCCC CCOc NCCS SCC COCCOC n CCCC NCC CNC S COCC OP COCC ON COCCC SCC COCCOCCOCC OCCOCCO CCOCCOCCOCC Nc N CCCCCCCCCCCCCC CCC OCCOCCOC CCCCCCCC CCOP COCC CCCn CCCCCCCCCCCC SCC OCCCO CCC NOC F SCCC SC F P N OCCCOc S CCOCCO ] )([ CCN CCO NCC l 23 1 CCS CCCNC COCCC OCCN ) # ccc oc OCC CCCOCC CO CCCCS CCCCCCCCCCCCC Oc CCCCOCC OCc OCCS Sc 9 6 F CCn S CCCCS nc sn Br CCN CS CCCCN COCC SCc COCC CCCNS COCCC OCCn F S N OCCNC O OCCC S CSCS NCC ON CS CCSCC CS CCCCn CCOCC Br NCCCC S CCCOCC CCC NCCS Sc COCCO CCCN NCCOCCOCC NS COCCOCCOCC n COCCOCCOCC OCCC P OC S OOC CCCN NC CCS CCCS CCCCCCCCCCC OCC OCCCCCCCC c NCCCCCCCC CCCCNC P Oc S CCCOCC OCC CCCSc cnc nn OCCCC OCc CCCCCCCCCCCC NS CCCCOC N CSCCC SC OCCOCCOCCOCC NC OCCOCCOCCOCC OCCOCCOC NOCC F COCCOCCOCC OCc OCCCCCCC OC OCCCCCCCCC l 7 13 S SCCC NC OCC COCC F OCO S CCCCCCC SC NCCCC CCOP co nn OCCOCCOCCOCC OCC CCOCCOCCOCC OCCOC n p CO CCCCCCCCCC NCC OS CCS SCCN NN NN CCCO O CCCCO n CCCCCCCCCCCCC NC B NC M o S COCC c p OC OCCC Cl B CCN Nc COC ON CCCCCCCC Br CCOCC OCCCC OCCC NCc CCCCN P CCCCCCCCC Sc CCCCO OC COCCOC N COCCOC OCC NCCOCCOCC OCCOC NCCCCCCCC CCNC P Cc S CNC S CCCCc CN SC OCCC SCc OCCOCC c CCCCCCCCCCCCCCCC CCCCc NCCCC OCCc OS N 10 7 CCCCCCCCCCCCCC n CCCCCCCCCCCCCCC n S SCc CCC OCCOCCOCCOCCOCCOCCOCCOCC CN CCO CO OP CS CCSc CCO NCC OCCC I OCCCC NS CCCCCCCCCCCC P NCCCCC NS CCP C I Cc S CCCCCn CN I OP P OCCCCCC Nc CSCCCC CCNS COCCOCCC OCC 8 1 S CCCCCCCCCCCCCCCCCC CCO OP NS NC CNS N CCCCCCCCCCCC CCCNC COCCOCCC OCc NCCCOCCOCC OCCC 9 5 S CCCCCCCCC o nnc NC SCC Br CCCc COCC CCCOc CCNC l cnn o CCCO n NO OSc CCCCCCCCCC P NCCCCC n NCCOCCOCC OCCN OCCCCCCCCC OC CCCCCCCCCCCCO S F B F CCCNc P I S CCCCCc CCCC CCSCC NS Cc CCCCCCCCCCCCCCCC CCCCCCOC OO Sc CCCCS P 11 8 COCCOC NC SS CCCC SS Sc COCCOCCOCC OCCNC N OCCCCC S NCC NC SC COC SC NCC OCCn CCCCCCCC ON CCCCCCCC CCCCCN COCC CCCN CCS CCCCC OCCOCC F CCCCCCCCCCCCCCCC CCCCOc COCCC SCc COCCC OCCOCC NCCN P CCCOCC Cc 7 1 P O S CCCCCCCCCCC Z r c occc NC Sc CCCC NN CO I OCCCC OP COCCCC CCOC OCCSS CCO cn nnc CCO CCCS OCCCC CCOP As H F CCNc O CCCCCCCCCCCCCCCCCCCCCC s snc +] % CN CCCC CCOC OCc CCCN n CCS SCCNC CCCOC OC CCCS SC OO OOC OCOC OCOC OCCCCCCCC CCCS NCCOCC OCCO NCCCO CCC CCOCCOCCOCC OCCOCCC F e o cccc CCCC CCON CCCC CCCOCCC Cl CCCCC 12 9 CS COc CS CSCC CCCCCCCC OCCC CCCO OC NCCC P OCCOCC OCc NO NC COCCC OCCOCc OS O CCCCCCCCCCCCCCC S OCCCCCCCC CCCCO NCCOCCOCC OCCn BB B CCCOCCOCC OCCCNC 5 0 O SCC ] )=[ CCCO CCCCCC CCCCCCCCCCCCCCCC CCSCC NCCCC Sc CCCCCCCCCCCC CCCN OCOC OC SS SSc NCCCO P SCCCC CCO NCCOCCO CCCCCCCl OCCOCCOCCO CCCC CCCCOCCOCC OCCC COCCOCCOCCOCCOCC OC CCCC OCCOCCOC OCC NN CN CCNCC CCOC Sc CCCCCCCC CCNS CCOCC SC CCS CCSc NN P OCO O OCCOCC OCCOCc CCCS CCCNC NCCOCCOCC Oc NC B CCCC CCOS Br N CO CCCCCCCCCCCCCC CO CCCCCc CO CCCCCCc OCCCC CCCO CCCCCCCCCCCCCCCC CCCn CCCCCCCCCCCCCCCC CCCCCCCCCCCCCCC CCCCO B CCCCCCCCCCCCCCCCC NC NCCCOCC OCCO COCCOCCOCC OCCn SCCCC Sc CCOCCOCCOCC OCCO B CCCCC )(= [ CN NCc CS SS SCC Br OCCOCC SC CCCOC N CCCS N CCCCCCCCCCCCCCCC CCNc CCCCCCCCCCCC CCS CCCCCCCCCCCC CCOP CCCCCCCCCCCCC n NCCOCCOCC OCCNS COCCOCCOCC Nc COCCOCCOCC OCCN CCCOCCOCC OCC I CCC O OCCCC P OCC S B CN NCC CO SC CCCO CCCOC OCCCC SC CCCCCCCCCCCCCCCC SC CCCCCCCCCCCCCCCC CCSC 10 3 CCCOCC NS CCCCCCCCCCCCC OCC NCCCCCCCC Nc SSSSSSSSSSSSSSSS SSSSSSSSSSSSSSSS 6 9 8 2 S CCCNc CCC OCCOCCOCCOC OCC SCCC Br P CCN CCCC CN Oc CCCCC OCCCC CS Oc CS CCCCCCn CCS OOO OCCO NC OCCO CCCCCC 43 1 CCCCCCCCCCCCCCCC CCSc CCCCCCCCCCCCCCCC OCCCOP NCCCC CCS OCCCO CCCOC OCCCCCCCC CCCO SS CCNC COCCOCCOCC S OCCCCCCCCCC Br CCNCCN CCNCC N CCCCCCCCCCCCC CCC OCO CN CCCO CO CCCCCCCCCCC COCC CCCOCC 23 4 OCCO OC OCCO OCCO NCCS SC SCCC F N OCCN O SCc NC Br Cl CCCOc CCN OCC CCN CCCc CCCCCCCC SCC CCCCCCCC OS COCC OCCCCn CCS CCCc OCCOCC OCCn CCCCCCCCC SC CCCS Sc CCCS SCC NCCS CCCOC CCCCCCCCCCCCCCCCC N CCCCCCCCCCCCCCCCC n OCCOCCO P F CCCC F CCCOc N CCCCCCCCN CCC OCCOCCOc Cl CCCCc Br CCCCC CCN O CNC N nnc nn COCC OS NNC l OCCO O CCCCCCCCC P CCCS S NO CCCCCC OS OC CCOCCOCCOCC OCCN OCCCCCCCCC S CCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCNC P t S OOc CCCC OCCOCCOCCOCC Cl CCOc CCOCC OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC COCC OCCCCC CCO Oc CCO CCCO CCCO B OCCOCC OCCF OCCCC OS CCCS CCO CCCCCCCCCCCCCCCC CCCCCCOc 11 9 COCCO NCC CCCCOCC OCCC NCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOCCC F CCc N CCCCCCCCCCCCCCC c H o oc NC NS CN ON CS CCCCCn CCOC NC COCC P NS S CCCCCC F OCCC SCCC COCCC OCCNc CCCCCCCCCCC Br CCCCCCCCCCC SC CCCOCC S CCCOCC OCCO CCCCCCCCCCCCCC P CCCCCCCCCCCCCC Nc OCCCCCCCC Br CCP CCC CCOCCOCCOCCOCCOCC OCCO NCCOCCOCCOCCOCC OCCOCCOCCOCCC CCCOCCCOCCCOCCCO CCCOCCCOCCCOCCCO cccc cccc CS O CS CCCCCCCCCCCC CCCCCCCC CCCNc CCO CCCOCCC CCCCCCCCCCCCCCC OCC COCCCC CCOCC NCCCO N OCCOCCOCCOCCOCCOCCOCCOCC OC COB NC CCOCCOCCOCCOCCOCC OC PP P F OC O H P Cl Cl CCOC CN CCCN CO CCCCO nn oc CS SCCOC CCCCCCCC CCCOP COCC OCCCS CCS Nc cs sc OCCOCC Sc CCCS CCN CCCS SCCC CCCCCCCCCCCCCCCC Sc CCCCCCCCCCCCCCCC CCCCCCO OP O CCCCOC OC 10 6 NCCS S CP CC OCCS CCOC OCCCCCCCCC Br OOOO OO CCCOCCOCC NC COCCOCCOCCOCCOCC OCC COCCOCCOCCOCCOCC OCCOC OOOOOOOOOOOOOOOO OOOOOOOOOOOOOOOO N CCCCCCCCCNC P CCC S CCCCCOc ] #[ CCCC OCCCc OCC CCCON COC OCCCC COC OCCOC CS CSc CCCN OC COCC CCCOC CCS Cn OCCC SOOO OCCOCC OCCCl NCCS SCCC NCCOCC Nc CCCCOCC S OCCOCCOCCOCCOCCOCCOCCOCC OCCOCCO COCCOCCOCCOCCOCC Oc BBBB BBBB B CCC B Oc S CCCNS CCCC OCCOCCOCCOC CCN OS CN B CN NS CCCCC SCCC CS I CS CCCl CCCCCCCC l CCCCCCCCCCCC Br OCCOCCOCCOCC N OCCOCCOCCOCC OCCOCCOCCOC CCCOCC CCCOCC OB OC CCCCOCC Sc OCCS SC CB CC OCCCCCCCCC O S CCSCC S CCOCCC +] )([ CCCC CCOCCc Cl CCCNc CO p CS SCCNC CCNC S CCS CSCS 34 2 CCCCCCCCC OCc CCCS SS CCCCCCCCCCCCCCCC CCCOC CCCCCCCCCCCCCCCC CCCCCCCCCCCCCCCCC 13 1 NCCCC CCCN NCCCC CCNS CCCCCCCCCCCC OCCCNC CCCCS CCCCC OCCOCCOCCOCC OCCOCCOCCOCCO CCCCCCCCCCCCC OP CCCCCCCCCCCCCCCCCC P OCCCCC F COCCO CCCCN NCCCO CCCNC CCP c CCCCCCO CCCC NCCCCCCC Nc NOCCO N 5 5 O CCCCCCCCCCCCCCCCCCC S CCOCCOCC a s Br CCCOc CN CCl CCCCC OCCc CS CCSCc CCCCN OC CCCCCCCCC l OCCCC OCCC NO CCCO CCCCCCCCCCCC SCCC CCCCCCCCCC OCc CCCCOC n OCCOCCOCCOCC OCCOCCOc CCCCCCCCCCCCC S CB N CCOCCOCCOCC n SSSS S CCOCCOCCOCCOCCOCC OCC COCCOCCCC NS OCS CSCO CSCS CSC 1 12 9 3 F CCN O NCCC O OCCO cc p CCCC NNC CCCC OCCOCCOc CCOC Nc CCCCCCCC CCSCC CCOCC SCC CCOCC OP CCOCC ON COCC OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC 32 4 CCCO CCCCOCCC OCCO CCCO CCCCCCCCC OS OCCCC CCON NOC N CCCCS CCCNC NCCS CCNC SCCC SCC NCCOCCOCC OCCO NCCOCCOCC OCCOCc OCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOC OCCOCCO S NCCCCCCCC CCNc CCOCCOCCOCCOCCOCC OCCNC CCCCCCOCC Cc B BC C p S OCc OC OCO CCCC CCCNS Cl CCNc CO NN CO ON nn nnc NCC OCCCOC NCC OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC CS OCC CS CCCCCCCC CCOCC P CCCN CCC COCC Br SC P CCO SC CCS NC CCS CCSCCC OCCOCC Br OCCCC F OCCCC CCSc CCCS SCCCC CCCCCCCCCCCCCCCC CCCCOCC COCCC OCCS OCCCCCC OCc OCCCCCCCC Cc OCCS SCCC OCCCCCCC Br CCCCCCOCC CCC CCCOCCOCC OCCC CCCCCCCCCCCCCCCCCCOCC OP COOO Sc - [ 4 23 9 2 = % B CCCC NC I CCCC CCOCCOC Br CCOC CCN OCc CCN CCNC CCCCC B CCCCC NNC COC l nn ncc COCC OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC SC Nc CCS CCSC CCCO CCCl OS OON ON CCCCC CCCCS OOO 11 7 NOCC S OCCCCCCCC CCCl COCCCC CCO OCCOCCO CCCCCC OCCCS CCNC CCOCCOCC OCc COCCCS CCC CCOCCOCCOCCOCCOCC OCCN CCCOCCOCC OCCOCCC S CCCCCl cc s CCCC OCCO CCCC CCSCCC Cl CCCCCC CCN CCCNCC CCCCC OCCOc NCC OCCc CS CCCCCN CCCCCCCC CCOS CCOCC OCCc COCC OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC NN Nc SCC P OCO n OCCOCC CCC CCCCCCCCCCCCCCCC CCCCCCCCCCCCCCCCCCCC OP C OO F OCCOCCOCCOCC OCc OCCOCCOCCOCC OCCOCCOCCO NCCS CCC OCCCCCC SC OOO Sc OCCOCCOCCOCCOCCOCCOCCOCC OCCO CCCCCCOCC OCc CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC CCCCCCCCCCCCCCCC NCCOCCOCCOCCOCC NC OCCCCOCCCCOCCCCOCCCC OCCCCOCCCCOCCCCOCCCC 8 24 N OCCCCOc O NCCCC S ON T i ] (=[ cc o NC OCc cccc nc OCC SCCS Br CCOc CCCCC NCC CCCCC NN CCCCC OCCCCC COC F COC OCCc CO OCCC CO OCCOC CO CCCCCCCCCCCCC 12 1 CS CCCCCCN CNC NC CCOCC OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC CCS CN NCCC SCC CCCCCCC I CCCCCCCCC OCCC OCCCC I OCCCC P CCCS CCS CCCCCCCCCCCCCCCC CCCCN CCCCCCCCCCCCCCCC CCCCCCN NO Oc OCCOC OC COCCCC CCNC OCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOCCOC COCCOCCOCCOCCOCC OCCO 1 34 1 42 B I N NCCCc O OCCOC R h S NCc S CCCCNC S CCOCCOCCOCC CCC OCCOCCOCCO Cl S Cl CCOCC CN CCOC COC OP 12 4 CS CCCCCCCCCCCCCC CCCCCCCC CCOCCC COCC SCCC CCO CCCSc CCS CCCCCCCCCCCC CSC P CCCS CCc CCCCCCCCCCCCCCCC CCCCO CCCCCCCCCCCCCCCC CCCCCCc NO OC OP N OCCCO OCCCO CCCCCCCCCCC Sc SCCC Br NOCC Br SS Cl SCCCC CCSc CCCCCCCCCCCCCCCCCCCC CCCNC CCOCCOCCOCCOCCOCC OCCOC NCCOCCOCCOCCOCC OCCNC 2 43 I P N OCCn N CCCCCCCCOc O NNC S COCc S CCCCCCCCCCCCCC Cl COc OCC NCCS OCC OCCCNc CCN Sc CN OCCC CN CCCn NCC OCCCC CCCCCCCC OCCCNC COCC CCCO COCC CCCOCc CCO CCCCCCCC CCO CCCCOC CCO CCCOCC CCS CCCSc OS I CCCCCCCCCCCC OCCC OCCCO CCCC OO B OO OS CCCCS CCCC CCCCS CCN NCCO NC CCCCCCCCCCCCCCC Nc OCCCCC OCc OCCCCCCCC N OCCCCCCCC CCN COCCCC CCCOc CCP CC SCCCC Br COB N OCCOCCOCCO S CCOCCOCCOCCOCCOCC OCCC CCCOCCO CCCC SCCOCC Sc SSS SCCC COOS N np n NCCCOCCOCCO CCCN 6 0 8 3 N CCCCCCCCCCCCCCCCC O s S CCCCCCOc Cl CCCN Br CCCCOc CCN CCn CN F CN OCCOC cn ncn CO CCCCCCCCOc CO OCN CS CSCCO CCCCCCCC I CCCCCCCC SCc CCCCCCCC CCSS CCOCC OCCS CCS CS CCCCCC B OCCO OCCOc CCCCCCC F CCCS NC CCCS CCNC CCCS CCCO CCCCCCCCCCCCCCCC CCCCCCCCCCCCCCCCCC CCCCCCCCCCCCCCCC CCCCCCCCCCCCCCCCCCC CCCCCCCCCCCCCCCC CCCCCCCCCCCCCCCCCCCCC COCCC P COCCC OCCSc OS S OCCOC N OO Nc OCCOCCOCCOCC OCCC OB C OCCCCC I SS P 14 1 NCCCO CCCCOCCCNC OCCCCCCCCCCCC Br OCCOCCOCCOCCOCCOCCOCCOCC OCCOC CCSS CCOC CCCP C COB Nc SCCCCCC SC CCSCCS CCSCC SCCOCCOCC SC 5 13 9 1 F CCCCC N p N OCCCl O OCOC S CCCCCSc S OOOC n ccccc s p CCCC NCCS Cl Nc Cl CCSc CCN SC CN CCCCC CN CCOCC CN CCn CCCCC SS +]) - CO NCCC CS CCCCO CS CCCCl CS CSCCS CCCCCCCC OOC CCOCC OS CCOCC OCCCOC COCC l CCO CCCCc CCS CCCCCC NN n NN CCCC CCCO CCCOc OCCO B OCCO n CCCS Nc OP c COCCC OCCOCCC CCCCCCCCCCCC OCc 10 1 NOC OCCOC OO Oc CCCCS SC CCCOCC Sc OCCCCCC F COS N OCCCCCCCC CCc COCCCC Sc COCCOCC SC NCCCOCC OCCCNC CB Cc NCCOCCO N Te H OCCOCCOCCOCCO CCCCCCCCCCCC COCCOCCOCCOCCOCC OCCOCCOC OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC F CCCn S CCCCCCN S CCOCCOC s scc CCCC OCCCOC CCCC OCCCCOc CCCC CCCON Cl n Cl NC Cl CCn Cl CCCCOc CCN NCC NCC OCCCc CS SCCCC CCCCCCCC OCCCC CCO CCCCOc CCO OO CCS SS CCS SSC NS CCC CCCCCCC SCC CCCCN n CCCCCCCCC F CCCCO O 13 3 CCCCCCCCCCCC CCSCC CCCCCCCCCCCC CCCOP CCCCS Sc OCCOCCOCCOCC n OCCOCCOCCOCC OCCOCC CCCCCCCCCCCCCCCCC Oc OCCCCCCCC NC OCCCCCCCC CCS NCCCO CCCC OCCS CCOCC COCCOCCOCC OCCOCc CCCCCS Sc OCCCCCCCCCCCCCCCC CCCCCCC OOOO OOO CCCCOCCOCC OCCN CCOCCOCCOCCOCCOCC OCCOCCC NCS CSCN NCCCOCCOCC OCCCNc CCCCCCCO CCCC SO SC A u B Nc F CCCN N BC O NCCc O OCCc O OCCCCC P NC S COc S CCOCCS p n NC F OC OCCO Br CCCCCC CCCCC OOC CS CCCCCCc CS SN CS OOc CCCN B COCC OCCOCCCC SC I CCS OC NS CCc NNC O CCCNC l OCO OC CCCCCCCCC NS CCCCCCCCCCCCCCCC CCOS NO Nc NO OS OO CCCCCC NCCS CCc NCCS SCCN CP n OCCCCCCCC CCOCC OCCCCCCCC CCCc NCCOCC OCCON NCCCCCC Cc OCCS CCOc OCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOCCO 15 2 16 2 CCOCCOCC NS SSSS SC CCOCCOCCOCCOCCOCC OCCOCC CCCOCCCO CCCC OCCOCCOCC P CSS SCc COCCCO CCCCOc OCCOCCOCCOCCOCCOCCO P CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCNC 5 43 B Bc I CCCC N OCCCCCCOc O NO O NNc P S P n P CCCC S CSCC S CCCCOC OC SCC CCCC OCCOCCCC Cl CCCn Cl CCOCCC Cl CCOCCOc OCC OCO Br n CN CCOc CCCCC SCCN CCCCC SCCCC CO CCCCCCCCCCCCCCCCCCCC CS NN CS CCCCCOC CCCCCCCC F CCCCCCCC CCl CCCCCCCC CCNCC CCO CCCCCCCCCCCC NCCC NCC OCCOCC Cc CCCS CCCN CCCCCCCCCCCCCCCC P CCCCCCCCCCCCCCCC CCCN CCCCCCCCCCCCCCCC CCOCCC )- [ OCCOC P ns sc CP Oc CCCCCCCCCCCCCC SC NCCCN Sc CCCCCCCCCCCCCCCCC OCC COCCO CCCCCC OCCCCCCCC CCn SS CCOC COCCCC OCc SCCS Cc SCCS CO SCCS CCS CCCCCS P CCCCOCCC OCCCCC OCCOCCOCCOCCO S CCCCCCS SC COCCOCCOCCOCCOCC OCCOCC CCNCCN CCNCCN CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC SCSCS CO CSSS SCC 1 53 B S N i P o S NS S OS S CCCCCCn X e c pc NC SN CCCC CCSS Br CCCCCCC CCN CCOc CCN CCCN CO NCCc 12 5 CS CCCCCCCCCC CS CON CS SNC 21 4 CCCCCCCC NN CCCCCCCC CCCOS CCOCC l CCO Sc CCO CCCCCCCCC CCS CCCCCCCC CCCO Nc CCCCN B OCCOCC OCCSC OCCCC CCCN CCCS O CCCS CCOC CCCCCCCCCCCCCCCC CCCCCOC CCCCCCCCCCCCCCCC CCCCCCNC CCCCCCCCCCCCCCCC CCCCCCCCc NO B COCCC NCC OS P CCCCCCCCCCCC CCSc OCCCO CCCO OO OOO COCCNC S CCCCS N OCOC Oc NCCCCC S NCCS CCN NCCS CCO NCCS OOO NCCS SCCNc 11 4 CP Cc CP CCC SCCC OCc COCCOC OCCC OCCCCCCCC OP SS CCO CCCCCCN CC CCCCOCC OCCO OCCS P NCCCCCCCC CCCCN SCCCCC Br CCCCCCOCC OCCOC CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC CCCCCCCCC CCCOCCOCC OCCNC OCCOCCOCC I SO Sc CSS SCC CCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOC CCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOC OCCOOCCO OCCOOCCO CCCSSS SCCC 1 43 B OCC C o I CCc N CCCCCCCCc N OCCCCc O CCCCCCCCCCCCCCCCCCCCC S NN T a o o NC OCCOC OC NS OC SP CCCC CCOCCOc Cl CCOCCNc Br B Br CCCN CCN Oc CN CCCc CN CCCNc COC ONC CO F CS COCC CCCCCCCC B CCCCCCCC NCC CCCCCCCC CCCNS CCOCC F CCO I CCO ON CCS n CCS SCc CCS SSSC NS P NS OOC NS CCSCc CCCO OCC CCCO CCCCCCC cs n OCCC SS OCCC SCCNc OCO CCCC OCCO OCC CCCCCCCCC SCCCC OCCCC OCCCCOC CCCS CCCCCSC CCCS CCCSCCC CCCCCCCCCCCCCCCC NS CCCCCCCCCCCCCCCC CCCOc CCCCCCCCCCCCCCCC CCCCCc CCCCCCCCCCCCCCCC CCCCCCCCOC CCCCCCCCCCCCCCCC CCCCCCCCCCCCCCCCCCCCCC CCCCO OOC OP OC CCCCCCCCCCC P CCCCCCCCCCC OCc OO NC OO OCC OO OP OCCOCCOCCOCC OCCOCCOCCOc NCCS CCOc CP OC CCCCCCCCCCCCCCCCC Nc CCCCCCCCCCCCCCCCC OP COCCO n NOCC Sc OCCCCCCCC CCNC OCCCCCCCC CCCn CCOCCC OCCOC NP OC SS NC SCCS N OOO SC NCCOCCOCC OCCOc NCCOCCOCC OCCNc OCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOCCOCCOCCO SCCCC CCS CCCCCCO CCCCCC CCOCCOCCOCC OCCOc CCOCCOCCOCC OCCOCCO CCCCCS CCCCC COO OS OCCCCCCCCCCCCCCCC OC COCCOCCC Sc NCCCCO P NCCCCCCCC O NCCCCCCCC CCCNC SSSS SS OCCOCCOCCO P CCCCOCCOCC OCCn CCOCCOCCOCCOCCOCC NC CCCCCCS P CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC CCCCCCCCCCCCCCCCC NCS CN CCCOCCOCC N COCCOCCOCCOCCOCC OCCOCCO NCCOCCOCCOCCOCC OCCOCCOCCNC SCCOCC OCCO SCS CO COCCOCCOCCOCCOCCOCCOCCOCCOCC OC NCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCNC OOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO OOOOOOOO 9 35 B NPOC F CCCc F CCSc I CCCCC M n N NCCOc N CCCCCCCCCCOc P SOCC R e S CCCCCCCCCCCCCCC S CCCCCCc S CCOCCOc NC OP Cl CSc -] (= Br CCCCc CCN B CCN CCCCC CCCCC OCCOC COC OCCOc CO Br CO OCCCCOc 12 2 CS CCCCOc CCOC OCCOC CCOCC CCCOc COCC OCCOP CCO CCCCCCOc CCS CCCl CCS CSCCC CCS CCCSCCC NNC S OCCOCC OCCS CCCCCCCCC SCC CCCCCCCCC OCOC OCCCC OOC OCCCC OCCCCO CCCS CCCCC CCCCCCCCCCCCCCCC CCCCS CCCCCCCCCCCCCCCC CCCCOP COP OC NCCCC F CCCCCCCCCCCC OCCOC ON OC 10 2 CSCCC OCC CSCCC SCC CCCCCCCCCCC NCC OO SC CCCCS CSc NCCCCC OP 11 1 CP O COCCOC OCc NOCC Nc OCCCCCCCC S OCCCCCCCC n COCCCC CCS 35 1 COCCOCCOCC Sc CCCCCCO OC CCCCCS CCCCCC 17 3 OCCCCCCCCCCCCCCCC CCCCCCCC CCSS CCn SSSS SSS CCCCCCCCCCS CCCCCCCCCC CCCCCCCCCCCCO CCCN NCCOCCOCCOCCOCC OCCO COCCCO CCCC COCCCO CCCOC COCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCC COCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCCC OOS N NNNN NNNN CCCOCCCCCOCC CCCOCCCCCOCC CCSCSCS CCSC COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCNC 4 13 7 23 B COc H f N CCCCCCCCCCCCCCCCCCCCCCCC N BN P CCP S OP S CCCCCN S CCCCCCCCCCCCC S CCCCCCCCCCCCCCCCCCC S CCOS Z n ] )(= s cn s ssc CCCC CCSCc CCCC OCCCCOC CCCC OCCCCc CCCC CCCOS Cl Oc Cl CN Cl CCCSc Br CCCCCCc CCN CCOC CN OS CCCCC OCCN CCCCC OCCCCCC CCCCC OCCCc COC SCC COC OCOC COC OCCn CO OCCCC CO NCCOc CO CCCCCCCOC CO CCCCCCCCCCOC NCC OCCCO CS CCCCCCCCCCCCCCCC CS CCCCc CS CCOCCOCC CCOC OCCC CCCCCCCC OCCOCC CCCCCCCC OO CCCCCCCC OCOC CCCCCCCC CCSCCC CCOCC OCCCNC CCCN CCNCC COCC I COCC OCO COCC OCCCOCCC CCS COC CCS CCCSCC CCS CSCCCS NS SN NN CCCCC ]( # CCCO CCCCOc CCCO CCCOCC NCCC OCCOCCOCCOCC OCCC OCCOCC OCCC OCCCCC CCCCCCCCC ON CCCS CCCc CCCCCCCCCCCCCCCC CCOCc CCCCCCCCCCCCCCCC CCCCCCCCCCCCCCCCCCCCCCC CCCCO Nc NO CCCON CCCCNC l 13 5 13 6 NCCCC CCON CCCCCCCCCCCC SCc CCCCCCCCCCCC SS OCCCO CCCOCC OCCCO CCCOCCCOCCCOCCCO 10 4 OCCN P CCCCS NC NCCCCC OCC NCCS CSCCN CCCCCCCCCCCCCCC Br NOCC CCCOc OCCCCCCCC CCCN NP N SS O SS COC COCCCC CCN CCCCCCN N CCCCCO NC SCCS CCSC CCCCOCC OCCOCCCC OCCS CO OCCCCCCCCCCCC S NCCOCCOCC OCc SCCCC SC OCCOCCO OCCOCCO CSCCS CCS CCOCCOCCOCC c CCOCCOCCOCC NS OCCCCO OCC NCCCCCCCC CCCCOP SSSS Sc CCCCOCCOCC OCCOc CCOCCOCCOCCOCCOCC OCCOCCOCCOCCO OCCOCCOCCOCCO B SCCCCCC Br COCCOCCOCCOCCOCC OCCN OCS CO SO OCCS COCCCO CCCOc NCCCCCCCCC Nc np npn 6 6 F COC F CCCCCC I r I OC P d S CCCCCS S CCCCCCCl S CCCCCCCCCBr ] # OC OCCc OC SCCO Cl Sc Cl CCCCCOc OCC NOC Br CCCCCCCCC Br CCCCn Br CCCCCCOc CN CCCOc CN CCCCCCOCCCCc CO SCC 12 6 12 8 NCC OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC CS OCc CS COCc CS CCCCS CCOC ON CCOCC OCCCCC CCOCC OCCOS CCOCC OCCOCCCC COCC CCCl COCC OCCCc CCO CCCCCCC CCO CCCCOCC CCS CCCOCC CCS SCCc NS CCN NS Sc NN SC NN CCCCc CCCO CCCCCCOc SCC I CCCCCCC OCCCCC CCCCCCCCC I CCCOC Oc CCCOC OCC CCCCCCCCCCCCCCCC OS CCCCCCCCCCCCCCCC OCCCOC CCCCCCCCCCCCCCCC CCCCCCCOC NO Sc 13 8 COCCC Br COCCC OCCNC OS OOC OCCCO CCCOc NOC n NCCS CS CCCCCCCCCCCCC Nc CCCCCCCCCCCCC Br CCCCCCCCCCCCC SC CP N CP P CP Nc CCCCCCCCCCCCCCCCC S CCCCCCCCCCCCCCCCC Sc COCCOC P OCCCCC SC COCCO OC OCCCCCC I 42 5 NP Oc CCCCCOC N NCCCOCC OCc OCCCCCCCCCCCC n OCCCCCCCCCCCC CCOC OCCCN NC CB OC 15 8 CCCCCCO NC CCCCCCCCCCCCCCCCCCCC CCCO CCCCCCCCCCCCCCCCCCCC CCOP 16 3 NNCC F CCOCCOCC OCCCNC OCCCCCCC n NCCOCCO F CSCCCC CCSCC OCCCCCCCCCCCCCCCC CCCCCCCCCCCCCCCC OCCCCCCCCCCCCCCCC CCCCCCCCCCCC NCCCCO N 18 1 SCCCCC SC OCCOCCOCCOCCO P CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC CCCCCCCCCCCCCC NCCCCCCCCCCCC Nc CCCOCCOCC CCC COCCOCCOCCOCCOCC N COCCOCCOCCOCCOCC OCCOCCOc OCS CSCCO CSCS CSCSC CSCS CSCSCSC NCCOCCOCCOCCOCC OCC COCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOC CCCCCCCCCCCS SCCCCCCCCCCC CSCCOCC SCC NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOC 1 13 1 78 B COC C u F CCOC I CCCCCC P CCPc S NCCC S CCCCCCCCCCCCCCCCCCCCCC NC SCCC OC B OC SCCSCO CCCC NCc CCCC OCCCOc CCCC CCOCCOCC Cl CCSCc Cl CCCCCCNc CCN NS CCN CCl CN CCNc CN OCCCC CCCCC OO COC Br COC On CO OCCc CO CCCCCCCCCCCCCCCCC CO OCCSCCO NCC OCCOCCOCCOCCOC CS CNc CS CCCCCCCCC CS OS CS OO CS CCON CS SCCO CS SSC CS SSSS CS CCCCCSC CCOC SC CCCCCCCC SCCC CCOCC ONC COCC NCc COCC NN CCO OS CCO CCCSC CCS O CCS CCOCC NS O NS CCCC NN OCC CCCO CCCS SCC OCc NNC Oc OCCO CCCCS CCCCCCCCC OCCc OCCCC CCOCCC OCCCC CCCON OCCCC CCOCCOCCOCCOC CCCCCCCCCCCCCCCC Br CCCCCCCCCCCCCCCC OCc CCCCCCCCCCCCCCCC OCCC CCCCCCCCCCCCCCCC CCCOCC CCCCCCCCCCCCCCCC SCCC CCCCCCCCCCCCCCCC CCSCCC CCCCCCCCCCCCCCCC CCCCCCCc CCCCCCCCCCCCCCCC CCCCCCCCCCOC CCCCCCCCCCCCCCCC CCCCCCCCCCCCCCCCCCCCCCCC NO I NO CCCN CSCC F OP OCC COCCC OCCCCCOc OS CCC scc s CCCCCCCCCCCC NCC CCCCCCCCCCCC OCOC CCCCCCCCCCCC CCOCCC CCCCCCCCCCCC SSc CCCCCCCCCCCC CCCOS CCCCCCCCCCCC OCCOCCOCCOCCOC 45 3 CCCCCCCCCC I ON n CSCCC Sc CCCCS S CCCCS CCOC CCCCCN P CCCOCC OCCOCCCC 11 5 24 1 OCCCCCCCC CCOCCOCCOCCOC COCCOCC Sc COCCOCC SCC COCCOCC OCCOCCCC SCCS CCO CCCSCC SC COCCOCCOCC c COCCOCCOCC OCCOCCC OCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOC SCCCC F SCCCC CCOC CSCCS CCSC CCCCCCCCCCOC OC 17 1 18 8 COCCCS CCCC OCCOCCOCCO N OCCCCCCCCCCC SC CCOCCOCCOCCOCCOCC OCCOCCNC CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC CCCCCCCCCCCC CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC CCCCCCCCCCCCC CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC CCCCCCCCCCCCCCCCCCC 20 1 COCCOCCOCCOCCOCC OCCOCCOCCC CNCCN CCNCC NCCOCCOCCOCCOCC OCCOc SCCOCC OCCS COCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOCC SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS SSSSSSSSSSSSSSSS BBBBBBBB BBBBBBBB OCCCOOCCCO OCCCOOCCCO ( #[ B CCCCCC I Oc N OCO N OCCCNC N CCCCCCCCCCCCCCCCCCCC N OCCCCO N OCOP N BOC O OCO O NCCO S CCON S CCCCCCCCCCCCCCCCCCCC S NCN NC OCCC NC ON OC SSC CCCC OCCOP Cl Cn Cl CCCCSc Cl CNCCc cccc p OCC CCCOP Br COc Br CCCn CCN NCc CCN CCCCc CCN OP CN OCCCc CCCCC Nn COC NS COC OCCCCC COC OCCCCCCOc COC OCOCOC CO NCCCC CO CCCCCCCCOC CO CCCCCCCCCCOc CO BC CO CCCCCCCCOCC CO OOOOOOOO CO OOOOOO 12 7 nn no NCC OCCCCC CS B CS NCC CS ON CS CCCCCCO CS CCOCCOCCOCC CCOC l CCCCCCCC CCCl CCCCCCCC OCCOC CCCCCCCC SSc CCCCCCCC CCCON CCOCC OCCCCCC CCOCC OCCCc CCCN CCc CCCN SC COCC OCCCl CCS Oc CCS CCCNS CCS SN CCS CCOCCSCC NS OC NS NS ccn ccc OCCC SCCN OCO CCCCCCCCC CCCCCCC NCC CCCCCCC OCCOc CCCCCCCCC OCCCC OCCCC SCc OCCCC OCCCCC OCCCC CCOS CCCS CCOc CCCS CCCCCC CCCS CCCS CCCS SSSS CCCCCCCCCCCCCCCC CCCCNC CCCCCCCCCCCCCCCC CCNS CCCCCCCCCCCCCCCC CCCCCCCCCCCCc CCCCCCCCCCCCCCCC CCCCCCCCCCCCCCOC CCCCO OCC OP I 13 9 NCCCC CCCOc CCSCC P OS SOC CCCCCCCCCCCC CCOS ON CCN OCCOC Oc NOC l CCCCCCCCCCC I NCCN OC OO CCCCCCCC CCCCS Nc CCCCS CCOc CCCCS SCC OCCOCCOCCOCC Br OCCOCCOCCOCC OCCOCCOCC OCCOCCOCCOCC OCCOCCN NCCS P CP CCCC OB OBO CCCCCCCCCCCCCCC Sc CCCCCCCCCCCCCCC OCOC COCCOC Sc OCCCCCCCC CCl CCCCCCN P SCCS CCSCCS OCCS CCCC OCCOCCOCCOCCOCCOCCOCCOCC OCC OCCOCCOCCOCCOCCOCCOCCOCC OCCC OCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCO OCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOCCOCCO OCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOCCOCCOC CCCCCCCCOC n CB NC CSCCS CCSCC CCCCCCCCCCCCCCCCCCCC P OCCCS CCO CCOCCOCC F OCCCCCCCCC n CSCCCC SCC COO Nc NCCCCCCCC CCN NCCCCCCCC CCCS NCCCCCCCC CCCCO SCCCCC F CCCCCCCCCCCCCCCCCCCCCCCC CCO OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOC OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCO OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOCCO CCOCCOCCOCCOCCOCC OCCOCCOC CCOCCOCCOCCOCCOCC OCCOCCOCCOC CCOCCOCCOCCOCCOCC OCCOCCOCC CCCCCCOCC OCCOc SCCCCCC F CCCOCCOCC OCCOc COCCOCCOCCOCCOCC OCCC COCCOCCOCCOCCOCC OCCNC COCCOCCOCCOCCOCC OCCOCCOCCOC COCCOCCOCCOCCOCC OCCOCCOCCO COCCOCCOCCOCCOCC OCCOCCN 36 1 CSCS CSCSCC CCOO Sc COCCCCCC Br SCCCCCCCC Sc COCCOCCO NC COCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCC CCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCCC NOCCCC CCCOc SCOC OCOP CCCOCCOCCOCCOCC OCC CCSSS SCCC 1 45 4 12 6 54 F CN F Sc I Nc N b N CCCCCCCCCCCCCCCCCCCCCCCCCCCC O NCCS P SC P OCCC S CCCCCOC S CCCCCCCCc S CCNCC S CSN S OOCC o s o ccoc p nc CC p ccc pc NC OCCOCC OC NN CCCC PC Cl COC Cl NCC Cl CNc Cl CCCCCc Cl CCCCCNc OCC CCCOS CN CCSc CN OCCOc cn nnn CCCCC OCCO CCCCC OCOC CCCCC PC COC I COC OCCCc COC SS COC OCCCS COC OCCOCCNC CO OOC CO CCCCCCCc CO CCCCCCn CO CCCOS CS Cl CS CCCCCCC CS CCCCCCCCCCC CS SCN CS CCCCCCSC CCCCCCCC OCCOc CCCCCCCC CCON CCCCCCCC CCOCCOCCOCCOC CCOCC NCC CCCN OCC COCC SCCOc CCO p CCO CCCCO CCO CCCCCCCCCC CCO CCCCCCCCCCC CCO CCCCCCBr CCS CSC CCS SCCO NS I NS Cl NN F NN NNC NN OS ccn sc CCCO Sc CCCO CCCCc no n NNC NNC 34 5 CCCCCCC OCCOC OCCOCC OCCCCC CCCCCCCCC NN OCCCC SCC CCCS CCCOC CCCS SCCNC CCCS CCCSCCCC CCCCCCCCCCCCCCCC CCCCCO CCCCCCCCCCCCCCCC CCCCCCCCCCCCOC CCCCO CCCCN OP n OP Cl NCCCC CCCNS COCCC OCCCCC OS F CCCCCCCCCCCC l CCCCCCCCCCCC OCCCC 45 2 CCCCCCCCCC F OCCCO O OCCCO NC OCCCO CCCOCCCO CCCCOC Nc 10 46 NOC S NOC OCC OO I CCCCS CCc CCCCS CCCOC CCCCS SSCCCC OCCOCCOCCOCC OCCOCc OCCOCCOCCOCC OCCOCCF NCCCCC F NCCS SCCOC CCOP c CCCCCCCCCCCCC OS SCCC I SCCC P SCCC SCc CCCCCCCCCCCCCCC I CCCCCCCCCCCCCCCCC OCOCC COCCO F COS P OCCCCCCCC CCCCN OCCCCCCCC CCCCNC OCCCCCCCC CCOP CCOCCC NCC NP C 14 4 14 8 NCCOCC Sc NCCCO S NCCCO CCCCOCCC NCCCO CCCCOCCCN CSCCN CC OCCS CCCCCCCC OCCS CCON OCCS CSCO OCCCCCCCCCCCC CCO NCCOCCOCC n NCCOCCOCC OCCOO COCCOCCOCC OCCCCC COCCOCCOCC OCCCNC COCCOCCOCC OCCS SCCCC CCOP CCOS P CB B 15 5 CCCCCCO CCCOC CCOCCOCCOCC OCCn OCCCCCCCCCC F OCCCS CCCCCCCCCCCC 16 9 NCCOCCO CCCC Al H 17 4 CCCOP I COB OC OCCCCCCCCCCC Br CCCCOCCOCC OCCOCCO CCCCOCCOCC OCCOCCC CCOCCOCCOCCOCCOCC OCCOCCO CCOCCOCCOCCOCCOCC OCCOCCOCCN OCCOCCOCCOCCO N CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC CCCCCCCCCCCCCCCCCC COCCOCCOCCOCCOCC OCCOc CCCOCCCO CCCOC CCCCCCCO CCCCCC CSS COC CSCS CSCCS CCCCCCCCCCS CCO CCCCCCCCCCS Sc NCCCCCCN OCc NCCOCCOCCOCCOCC OCCOCCOCCOC NCCOCCOCCOCCOCC OCCOCCC NCCOCCOCCOCCOCC OCCOCCNC CCCCCCCCCCO CCCCCCCCCCO Bi H SCCOCC OP 30 1 NCCCCCCCCCCCCCCCC O COOO SC OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOC CCCOCCCOCCCOCCCOCCCOCCCOCCCOCCCO CCCOCCCO OOOOOO OOO NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOCCC COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC SCCOCCOCCOCC S OCCSCCOCC SCCO NCCSCS CSCCN 2 24 A t B CN B SOC B CSOCC F Oc F CCOCC F CCCSc I S I Sc I CCCc N CCCCCCCCCCCCCCCCCCC N CCCCCCCCOC N OCCCCNC N OCON P Nc S OCCC S CSCc S NCCO S CCCCCCCCCOc S CCOCCOCCOCCOCCOCC S CCCCCCCCCCCCCCCCCCCCCCCCCCCC S CCCCCCCSc T c c on CC BC ccc sc NC SCCS NC SOOO OC SN Cl OC Cl CCCSCc Cl CCCCCCSc Cl CCOCCSc OCC NNC OCC OCCCOc Br Nc Br CCn Br CCSc Br CCCCCOc Br CCCCSc CCN CCNc CCN SCc CCN CCSc CN CCCCCCC CN OP CCCCC OB COC SSC CO OCCO CO NCCN CO NCCOC CO OCCCc CO CCCCCCCCCCCCOc CO CCCCCCCCCCCOc nn ccn NCC OCCCCO CS NCc CS CCCCCCCCCCCCCCCCCC CS CCOCCS CS OOOC CS OON CCOC I CCCCCCCC OCCCCC CCCCCCCC OCCCN CCCCCCCC CCCOCCC CCOCC I CCOCC SCc CCOCC OCCCl CCOCC OCCSc CCOCC OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC CCCN Nc COCC CCCS COCC NCCS COCC SCCCC COCC OCCOS SC Br 23 5 CCO OCCC CCO OCCCC CCO CCCCCc CCO CCCCNc CCO CCCCCCOC CCO CCCCCCO CCO OCCCCOc CCO OCCCCCCOc CCS I CCS CCCCO CCS OS CCS CCOP CCS SCCCC CCS CSCCCO CCS CSCCSC NS SC NS SNC CCCO CCCCCCCCC CCCO CCCCO OCCC OCCOc OCO I OCO OCc CCCCCCC B CCCCCCC OCCCc CCCCCCC SS CCCCN OCc OCCOCC NS OCCOCC OCCBr CCCCCCCCC OCCCCCCCCC CCCCCCCCC OCCOP OCCCC OCCCO CCCS CS CCCS CCCOc CCCS SN CCCCCCCCCCCCCCCC l CCCCCCCCCCCCCCCC CCCNC CCCCCCCCCCCCCCCC CCCS CCCCCCCCCCCCCCCC CCCNc CCCCCCCCCCCCCCCC CCOCCCC CCSC Nc COP C NCCCC P NCCCC CCSc COCCC OCCO COCCC OCCOCCOc OS Oc OS SC CCCCCCCCCCCC SP OCCCO OC OCCCO CCCCCCCCCCCCCCCC OCCCO CCCOCCCOC CCCCCCCCCCC SCC ns n OO OCCCC CCCCS CCO CCCCS CCS CCCCS CCCO OCOC P OCOC OCC NCCS SNC CCOP C 11 6 CCCCCCCCCCCCC l CCCCCCCCCCCCC Sc CCCCCCCCCCCCCC Br CCCCCCCCCCCCCCCCC SCC COCCCN NC COS I COS OOO OCCCCCCCC CCCNC OCCCCCCCC CCCCc NP I SS SSCC SS COCCCCOC COCCCC OCCC CCCCCCN CCS NCCOCC OCc NCCCCCC P CCCCCOC n NCCCO n NCCCO CCCCOCCCNc CCCCOCC P OCCCCCCCCCCCC OCc OCCCCCCCCCCCC CCOc CCP P OOO OCC COCCOCCOCC F COCCOCCOCC SCC OCCCN N SCCCS CCC CCOS I 15 1 CCCCCCO CCCN CCOCCOCCOCC OCCCc OCCCCCCCCCC OCc SCCO CCCl 16 6 17 7 OCCCCCCCCCCCCCCCC O NCCCCCCCC CCCc OCP CC OCCCCCCCCCCC OCC CCCCOCCOCC c COOC SCO COOC SCSCO CCCCCCCCCCCCCCCCCCCCCCCC CCCCO COCCOCCOC OC CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC CCCCCCCCCCCCCCC NCS CSCS PP PP COCCOCCOCCOCCOCC OCCOCCOCCOCc COCCOCCOCCOCCOCC OCCOCCOCCP CCB CC OCCCCCCO OCC NOCCO S Sb H CSS CCCOC CSCS COC CSCS CO CSCS CSCC CSCS CSCCO Pb H COCCCCCC OCc CCCCCCCCCCS P SCCOCC SC CCSCCS CCSCCC CCSCCS CCSCCSCC OCCSS CCNC COCCOCCO CCCCCC CCCCCCCCCCCO CCCC CCCCCCCS CCCCCCC COCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOC COCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOc CCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOCC CCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCC CCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCC OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC NCCOCCOCCOCCOCCOCCOCCOCCOCC NC NCCOCCOCCOCCOCCOCCOCCOCCOCC OCCOCCOCCOC CCOCCOCCOCCO P SCCCCCCC F CSCCOCC SCc CCCOCCOCCO CCCN ccp cc CCCCCCCCCCSS CCCCCCCCCCC CCCCCSS CCCCCC OCCSCCOCC OCCSCCO 2 45 5 12 5 34 6 13 7 0 B F B CCN B CNC B CCOc B Sc B OO B OCCNc E u F NC F Nc F CCSC F CCCCc F CCCCOc F CCCCCc F CCOCCOCCOc I CCOc I SC L i N a N OCCOCC N NCCSCc N Bc N OCCCS N CCCCCCCCCCCCCCCCCCCCCC N CCCCCCCCCCCCCCCCCCCCCCC N OCCCCCc N CCCCCCCCCN O OCCCCO P Br P CCCCC P CCc P OCc P BB P BI S CCCCCNC S CCCCCCCCCCCCCCCCC S CCCCCCCCOc S CCOCCN S CCCCCCCCCCCCCCCCCCCCCCCC S CCOCCOCCOC p p p cc CCC p CCC OCCOP CCC OCCOCCOCCOCCOC CCC OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC NC OCCO NC OS OC OCCOCCOCC CCCC OCCOCCOCCO CCCC OCCCCS Cl CCCCCCOc Cl CNCc cccc ccn OCC OCCCNC |