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license: mit
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---
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---
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license: mit
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+
language:
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- en
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metrics:
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- f1
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- accuracy
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- roc_auc
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base_model:
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- microsoft/deberta-v3-base
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pipeline_tag: text-classification
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tags:
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- medical
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- pharmacovigilance
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- clinical-nlp
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- drug-safety
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- adverse-drug-reactions
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- deberta
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- classification
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datasets:
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- custom
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model-index:
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- name: MedSentinel ADR Severity Classifier
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results:
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- task:
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type: text-classification
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name: ADR Severity Classification
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metrics:
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- type: f1
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value: 0.9272
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name: Accuracy (Kaggle)
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- type: accuracy
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value: 0.9440
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name: Accuracy (Test set)
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---
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# MedSentinel — ADR Severity Classifier
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**MedSentinel** is a fine-tuned [DeBERTa-v3-Base](https://huggingface.co/microsoft/deberta-v3-base)
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model for classifying the severity of Adverse Drug Reactions (ADRs) from patient-reported
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narrative text. It is the core AI component of the MedSentinel ADR Intelligence Platform,
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designed to assist clinical practitioners in triaging pharmacovigilance signals.
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## Model Details
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| Property | Value |
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|---|---|
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| **Base model** | microsoft/deberta-v3-base |
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| **Architecture** | DeBERTa-v3 (12 layers, 768 hidden, ~86M params) |
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| **Task** | Binary text classification (Severe / Non-Severe) |
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| **Training strategy** | 5-fold stratified cross-validation ensemble |
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| **Kaggle score** | 0.92720 (ensemble) · 0.91544 (single model) |
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| **Tokenizer** | SentencePiece (max length 256) |
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## Intended Use
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This model is intended for **research and clinical decision support** in the context of
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pharmacovigilance. It classifies free-text patient ADR reports as either severe or
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non-severe to help clinicians prioritize signals requiring immediate attention.
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**Intended users:** Clinical practitioners, pharmacovigilance researchers, healthcare data scientists.
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**Out-of-scope uses:** This model should not be used as a sole basis for clinical decisions.
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It is a decision-support tool and should always be reviewed by a qualified healthcare professional.
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## Training Data
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The model was trained on a dataset of **8,153 patient-reported drug experience narratives**
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sourced from drug review platforms. Labels indicate ADR severity:
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- `0` — Non-severe adverse drug reaction
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- `1` — Severe adverse drug reaction
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**Class distribution:** 53.4% severe · 46.6% non-severe (near-balanced)
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## Training Configuration
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```python
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# Key hyperparameters
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learning_rate = 2e-5
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optimizer = "adafactor"
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batch_size = 16 # effective 64 with gradient accumulation
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gradient_accumulation = 4
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epochs = 8 # with early stopping (patience=3)
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warmup_ratio = 0.1
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lr_scheduler = "cosine"
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weight_decay = 0.01
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max_seq_length = 256
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fp16 = False # DeBERTa-v3 incompatibility
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cv_folds = 5
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```
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## Evaluation Results
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| Metric | Score |
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|---|---|
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| **Kaggle F1 (ensemble)** | **0.92720** |
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| Kaggle F1 (single model) | 0.91544 |
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| Validation F1 (macro) | 0.9050 |
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| Validation accuracy | 94.4% |
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## How to Use
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```python
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from transformers import AutoTokenizer, AutoModelForSequenceClassification
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import torch
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from scipy.special import softmax
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model_id = "Izziemirg/medsentinel-adr-deberta"
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tokenizer = AutoTokenizer.from_pretrained(model_id)
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model = AutoModelForSequenceClassification.from_pretrained(model_id)
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model.eval()
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def classify_adr(text):
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inputs = tokenizer(
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text,
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return_tensors="pt",
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truncation=True,
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max_length=256,
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padding=True
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)
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with torch.no_grad():
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logits = model(**inputs).logits.numpy()
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probs = softmax(logits, axis=-1)[0]
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label = "Severe" if probs[1] > 0.5 else "Non-Severe"
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return {"label": label, "confidence": round(float(probs.max()), 4)}
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# Example
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text = "I experienced severe insomnia, heart palpitations, and extreme anxiety
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after taking this medication for two weeks."
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print(classify_adr(text))
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# {'label': 'Severe', 'confidence': 0.9731}
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```
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## Limitations
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- Trained on English-language patient-reported text only
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- Performance may degrade on formal clinical notes (different register than training data)
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- Mixed-sentiment texts (severe symptoms but positive drug efficacy) remain a known
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edge case — the model may under-predict severity in these cases
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- Not validated on real-world clinical deployment data
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## Citation
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If you use this model in your research, please cite:
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```bibtex
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@misc{mirghani2025medsentinel,
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title = {MedSentinel: ADR Severity Classification with DeBERTa-v3},
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author = {Mirghani, Izzie},
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year = {2026},
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howpublished = {HuggingFace Hub},
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url = {https://huggingface.co/Izziemirg/medsentinel-adr-deberta}
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}
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```
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## Developed By
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**Izzie Mirghani** MS Business Analytics, UVA Darden
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Part of the **MedSentinel ADR Intelligence Platform** project.
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